|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
20-486 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 968.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 20 VYLPEEFLAQMRAAMPTHLSFDDFIAACQRPLRRSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIEREDEDDLP 99
Cdd:PRK11933 2 VYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEDALP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 100 LGSAAEHLSGLFYIQEASSMLPVAALFADGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRC 179
Cdd:PRK11933 82 LGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISRC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 180 GISNVALTHFDGRVFGAALPECFDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYS 259
Cdd:PRK11933 162 GVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVYS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 260 TCTLNRQENEEVVNGLLARYPQAVEVVPLGSLFPQASEALTEEGFLHVFPQIFDCEGFFVARLRKTAAIDPLPAPGYKVG 339
Cdd:PRK11933 242 TCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKVG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 340 KFPFTPLKTRESAAVIAAAAAVGLQWTADHTLWQRDKEIWLFPQALEALFGKVRFSRIGIRLAETHNKGYRWQHEAVIAL 419
Cdd:PRK11933 322 KFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIAL 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1031301922 420 AAPTAPLALT--EAEAEEWYRGRDIYPETLPQKDDAIVTYQGAPIGLAKKVGSRLKNSYPRELVRDGKL 486
Cdd:PRK11933 402 ASPDNANAFEltPQEAEEWYMGRDIYPQTAPPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGKL 470
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
55-324 |
8.18e-135 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 389.90 E-value: 8.18e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 55 IRVNTLKITVADFLQLVAPYRWQLtpVPWCEEGFWieREDEDDLPLGSAAEHLSGLFYIQEASSMLPVAALFADGqmPKR 134
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVL--EPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPRE--DER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 135 VMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEcFDAILLDAPCSGE 214
Cdd:TIGR00446 75 VLDMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 215 GVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNRQENEEVVNGLLARYPQAVEVVPLGSLFPQ 294
Cdd:TIGR00446 154 GVIRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFG 233
|
250 260 270
....*....|....*....|....*....|.
gi 1031301922 295 ASEAL-TEEGFLHVFPQIFDCEGFFVARLRK 324
Cdd:TIGR00446 234 INIGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Ncl1 |
COG3270 |
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and ... |
26-482 |
5.24e-104 |
|
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442501 [Multi-domain] Cd Length: 452 Bit Score: 318.18 E-value: 5.24e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 26 FLAQMRAAMPTHLSFDDFIAACQRPLRRSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIEREDEDDLPLGSAAE 105
Cdd:COG3270 3 PLLELFQLMMLLLLEEEAAFAAALRLLRRSSLRVLLLKAAEDLALRLLAPPPLLPPPPWPEGGGYEEDEELGGPLGLAAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 106 HLSGLFYIQEASSMLPVAALFADGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVA 185
Cdd:COG3270 83 ALYYLQEAAAASSALPVAALPGLLLLLAAAAGGAAATAAAAAQGGLLLNLLNIILALELLASSVEVLHANIVVVVNTNTP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 186 LTHFDGRVFGAALPECFDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNR 265
Cdd:COG3270 163 LAELAGFVFFDALDADADASLLGGGFPREGAAAKEADPLRKASAEIQLEIEAAAAAALLLGGGALLLTTTTEPSEEEEEE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 266 QENEEVVNGLLARYPQAVEVVPLGSLFPQASEALTEEGFLHVFPQIFDCEGFFVARLRKTAAIDPLPAPGYKVGKFPftp 345
Cdd:COG3270 243 EELLLLLEELDLALEPAVEEGAGEGGDPEAAAALTELLGLHRFPPHGEGGGGFFAALKKKAGDEPSPKKKKKKKKPK--- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 346 lktrESAAVIAAAAAVGLQWTADHTLWQRDKEIWLFPQALEALfGKVRFSRIGIRLAETHNKGYRWQHEAVIALAAPTAP 425
Cdd:COG3270 320 ----QAKEVLRAFAEEGLPLPEVGRLWERGGKLYLLPEELPDL-SGLKVLRIGLKLGEIKKKRFEPSHALALALGPEATK 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1031301922 426 LAL--TEAEAEEWYRGRDIYPETlPQKDDAIVTYQGAPIGLAKKVGSRLKNSYPRELVR 482
Cdd:COG3270 395 NVVelDAEEALRYLKGEDIELED-GDKGWVLVTYDGYPLGWGKYVGGRLKNHYPKGLRR 452
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
134-323 |
1.05e-52 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 176.85 E-value: 1.05e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 134 RVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEC-FDAILLDAPCS 212
Cdd:pfam01189 11 TILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGVlFDRILLDAPCS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 213 GEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNRQENEEVVNGLLARYPQaVEVVPLGSLF 292
Cdd:pfam01189 91 GTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHPD-VELVPTPLFE 169
|
170 180 190
....*....|....*....|....*....|.
gi 1031301922 293 PQAsEALTEEGFLHVFPQIFDCEGFFVARLR 323
Cdd:pfam01189 170 PVG-LAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
134-259 |
8.13e-04 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 38.95 E-value: 8.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 134 RVMDVAAAPGSKTTQIAARMGNEggILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPECFDAILLDAPCSg 213
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGAR--VTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESFDVIISDPPLH- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1031301922 214 egvvrkdpdalknWSPESnaeiavtQRELIDSAFHALRPGGTLVYS 259
Cdd:cd02440 78 -------------HLVED-------LARFLEEARRLLKPGGVLVLT 103
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| yebU |
PRK11933 |
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed |
20-486 |
0e+00 |
|
rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed
Pssm-ID: 183387 [Multi-domain] Cd Length: 470 Bit Score: 968.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 20 VYLPEEFLAQMRAAMPTHLSFDDFIAACQRPLRRSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIEREDEDDLP 99
Cdd:PRK11933 2 VYLPDAFLTQMREAMPSHLSMDDFIAACQRPLRRSIRVNTLKISVADFLQLMAPYGWTLTPIPWCEEGFWIERDDEDALP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 100 LGSAAEHLSGLFYIQEASSMLPVAALFADGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRC 179
Cdd:PRK11933 82 LGNTAEHLSGLFYIQEASSMLPVAALFADDNAPQRVLDMAAAPGSKTTQIAALMNNQGAIVANEYSASRVKVLHANISRC 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 180 GISNVALTHFDGRVFGAALPECFDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYS 259
Cdd:PRK11933 162 GVSNVALTHFDGRVFGAALPETFDAILLDAPCSGEGTVRKDPDALKNWSPESNLEIAATQRELIESAFHALKPGGTLVYS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 260 TCTLNRQENEEVVNGLLARYPQAVEVVPLGSLFPQASEALTEEGFLHVFPQIFDCEGFFVARLRKTAAIDPLPAPGYKVG 339
Cdd:PRK11933 242 TCTLNREENQAVCLWLKETYPDAVEFEPLGDLFPGAEKALTEEGFLHVFPQIYDSEGFFVARLRKTASVPRLPAPKYKVG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 340 KFPFTPLKTRESAAVIAAAAAVGLQWTADHTLWQRDKEIWLFPQALEALFGKVRFSRIGIRLAETHNKGYRWQHEAVIAL 419
Cdd:PRK11933 322 KFPFTPAKDKEAQEIRQAAASVGLSWPENLRLWQRDKEVWLFPAGIEPLIGKVRFSRIGIKLAETHKKGYRWQHEAVIAL 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1031301922 420 AAPTAPLALT--EAEAEEWYRGRDIYPETLPQKDDAIVTYQGAPIGLAKKVGSRLKNSYPRELVRDGKL 486
Cdd:PRK11933 402 ASPDNANAFEltPQEAEEWYMGRDIYPQTAPPAGEVIVTYQGQPIGLAKRVGNRLKNSLPRELVRDGKL 470
|
|
| nop2p |
TIGR00446 |
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base ... |
55-324 |
8.18e-135 |
|
NOL1/NOP2/sun family putative RNA methylase; [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 188051 [Multi-domain] Cd Length: 264 Bit Score: 389.90 E-value: 8.18e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 55 IRVNTLKITVADFLQLVAPYRWQLtpVPWCEEGFWieREDEDDLPLGSAAEHLSGLFYIQEASSMLPVAALFADGqmPKR 134
Cdd:TIGR00446 1 IRVNTLKINVEDLLERLENRGVVL--EPTCEEYFF--EVKESPFSIGSTPEYLFGYYYPQEASSMIPPIALEPRE--DER 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 135 VMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEcFDAILLDAPCSGE 214
Cdd:TIGR00446 75 VLDMAAAPGGKTTQISQLMKNKGCIVANEISKSRTKALISNINRMGVLNTIVINADGRKFGAYLLK-FDAILLDAPCSGE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 215 GVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNRQENEEVVNGLLARYPQAVEVVPLGSLFPQ 294
Cdd:TIGR00446 154 GVIRKDPSRKRNWSEEDIKYCSLLQKELIDAAIDALKPGGVLVYSTCSLEVEENEEVIDYILRKRPDVVEEIIKGDEFFG 233
|
250 260 270
....*....|....*....|....*....|.
gi 1031301922 295 ASEAL-TEEGFLHVFPQIFDCEGFFVARLRK 324
Cdd:TIGR00446 234 INIGKgEVKGALRVFPQNYDCEGFFVAKLRK 264
|
|
| Ncl1 |
COG3270 |
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and ... |
26-482 |
5.24e-104 |
|
Ribosome biogenesis protein, NOL1/NOP2/FMU family [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442501 [Multi-domain] Cd Length: 452 Bit Score: 318.18 E-value: 5.24e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 26 FLAQMRAAMPTHLSFDDFIAACQRPLRRSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIEREDEDDLPLGSAAE 105
Cdd:COG3270 3 PLLELFQLMMLLLLEEEAAFAAALRLLRRSSLRVLLLKAAEDLALRLLAPPPLLPPPPWPEGGGYEEDEELGGPLGLAAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 106 HLSGLFYIQEASSMLPVAALFADGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVA 185
Cdd:COG3270 83 ALYYLQEAAAASSALPVAALPGLLLLLAAAAGGAAATAAAAAQGGLLLNLLNIILALELLASSVEVLHANIVVVVNTNTP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 186 LTHFDGRVFGAALPECFDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNR 265
Cdd:COG3270 163 LAELAGFVFFDALDADADASLLGGGFPREGAAAKEADPLRKASAEIQLEIEAAAAAALLLGGGALLLTTTTEPSEEEEEE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 266 QENEEVVNGLLARYPQAVEVVPLGSLFPQASEALTEEGFLHVFPQIFDCEGFFVARLRKTAAIDPLPAPGYKVGKFPftp 345
Cdd:COG3270 243 EELLLLLEELDLALEPAVEEGAGEGGDPEAAAALTELLGLHRFPPHGEGGGGFFAALKKKAGDEPSPKKKKKKKKPK--- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 346 lktrESAAVIAAAAAVGLQWTADHTLWQRDKEIWLFPQALEALfGKVRFSRIGIRLAETHNKGYRWQHEAVIALAAPTAP 425
Cdd:COG3270 320 ----QAKEVLRAFAEEGLPLPEVGRLWERGGKLYLLPEELPDL-SGLKVLRIGLKLGEIKKKRFEPSHALALALGPEATK 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 1031301922 426 LAL--TEAEAEEWYRGRDIYPETlPQKDDAIVTYQGAPIGLAKKVGSRLKNSYPRELVR 482
Cdd:COG3270 395 NVVelDAEEALRYLKGEDIELED-GDKGWVLVTYDGYPLGWGKYVGGRLKNHYPKGLRR 452
|
|
| RsmB |
COG0144 |
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and ... |
11-326 |
3.96e-94 |
|
16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 439914 [Multi-domain] Cd Length: 441 Bit Score: 292.30 E-value: 3.96e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 11 GALPVAQNAVY--LPEEFLAQMRAAM-PTHLsfDDFIAACQRPLRRSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEG 87
Cdd:COG0144 134 AADPVERLAVRysHPEWLVERLRAAYgPEEA--EALLAALNEPPPLDLRVNTLKASREELLARLAEEGIEAEPTPLSPDG 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 88 FWIEredeDDLPLGSAAEHLSGLFYIQEASSMLPVAALfaDGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSAS 167
Cdd:COG0144 212 LRLE----GPGPVTALPGFREGLFSVQDEASQLVALLL--DPKPGERVLDLCAAPGGKTLHLAELMGNKGRVVAVDISEH 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 168 RVKVLHANISRCGISNVALTHFDGRVFGAALPECFDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAF 247
Cdd:COG0144 286 RLKRLRENLARLGLSNVEVVVADARELLEWLPGKFDRVLLDAPCSGTGTLRRHPDIKWRRTPEDIAELAALQRELLDAAA 365
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1031301922 248 HALRPGGTLVYSTCTLNRQENEEVVNGLLARYPQAvEVVPLGSLFPQAseALTEEGFLHVFPQIFDCEGFFVARLRKTA 326
Cdd:COG0144 366 RLLKPGGRLVYSTCSLLPEENEEVVEAFLARHPDF-ELVPLAELLPGL--ALTDGGYLRLLPHRHGTDGFFIARLRKKA 441
|
|
| PRK14902 |
PRK14902 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
54-324 |
9.43e-75 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 237857 [Multi-domain] Cd Length: 444 Bit Score: 242.00 E-value: 9.43e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 54 SIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIERededdlplGSAAEH---LSGLFYIQEASSMLPVAALFADGQ 130
Cdd:PRK14902 180 SIRVNTLKISVEELIEKLEEEGYEVEESLLSPEALVIEK--------GNIAGTdlfKDGLITIQDESSMLVAPALDPKGG 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 131 MpkRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPECFDAILLDAP 210
Cdd:PRK14902 252 D--TVLDACAAPGGKTTHIAELLKNTGKVVALDIHEHKLKLIEENAKRLGLTNIETKALDARKVHEKFAEKFDKILVDAP 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 211 CSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNRQENEEVVNGLLARYPQaVEVVPLGS 290
Cdd:PRK14902 330 CSGLGVIRRKPDIKYNKTKEDIESLQEIQLEILESVAQYLKKGGILVYSTCTIEKEENEEVIEAFLEEHPE-FELVPLQH 408
|
250 260 270
....*....|....*....|....*....|....
gi 1031301922 291 LFPQASEALTEEGFLHVFPQIFDCEGFFVARLRK 324
Cdd:PRK14902 409 EKPDELVYEVKDGYLQILPNDYGTDGFFIAKLRK 442
|
|
| Methyltr_RsmB-F |
pfam01189 |
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ... |
134-323 |
1.05e-52 |
|
16S rRNA methyltransferase RsmB/F; This is the catalytic core of this SAM-dependent 16S ribosomal methyltransferase RsmB/F enzyme. There is a catalytic cysteine residue at 180 in UniProtKB:Q5SII2, with another highly conserved cysteine at residue 230. It methylates the C(5) position of cytosine 2870 (m5C2870) in 25S rRNA.
Pssm-ID: 426109 [Multi-domain] Cd Length: 199 Bit Score: 176.85 E-value: 1.05e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 134 RVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEC-FDAILLDAPCS 212
Cdd:pfam01189 11 TILDMCAAPGGKTTHIAELMKNQGTVVAVDINKHRLKRVAENIHRLGVTNTIILNGDGRQPDQWLGGVlFDRILLDAPCS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 213 GEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNRQENEEVVNGLLARYPQaVEVVPLGSLF 292
Cdd:pfam01189 91 GTGVIRRHPDVKWLRQEADIAQLAQLQKELLSAAIDLLKPGGVLVYSTCSVLPEENEAVIEYFLQKHPD-VELVPTPLFE 169
|
170 180 190
....*....|....*....|....*....|.
gi 1031301922 293 PQAsEALTEEGFLHVFPQIFDCEGFFVARLR 323
Cdd:pfam01189 170 PVG-LAIGEQPTLRLLPHTHNGDGFFIAKLR 199
|
|
| PRK14901 |
PRK14901 |
16S rRNA methyltransferase B; Provisional |
45-326 |
1.82e-47 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237856 [Multi-domain] Cd Length: 434 Bit Score: 169.72 E-value: 1.82e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 45 AACQRPLRRSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIE--REDEDDLPlGSAAehlsGLFYIQEASSMLpV 122
Cdd:PRK14901 171 KWFNQPPSLDLRINPLRTSLEEVQAALAEAGITATPIPGLPQGLRLTgnPGSIRQLP-GYEE----GWWTVQDRSAQL-V 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 123 AALFaDGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPEC- 201
Cdd:PRK14901 245 APLL-DPQPGEVILDACAAPGGKTTHIAELMGDQGEIWAVDRSASRLKKLQENAQRLGLKSIKILAADSRNLLELKPQWr 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 202 --FDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNRQENEEVVNGLLARY 279
Cdd:PRK14901 324 gyFDRILLDAPCSGLGTLHRHPDARWRQTPEKIQELAPLQAELLESLAPLLKPGGTLVYATCTLHPAENEAQIEQFLARH 403
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1031301922 280 PQAVEVVPlgslfPQasealteegflHVFPQIFDCEGFFVARLRKTA 326
Cdd:PRK14901 404 PDWKLEPP-----KQ-----------KIWPHRQDGDGFFMAVLRKKS 434
|
|
| PRK14904 |
PRK14904 |
16S rRNA methyltransferase B; Provisional |
49-326 |
7.36e-38 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 237858 [Multi-domain] Cd Length: 445 Bit Score: 143.66 E-value: 7.36e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 49 RPLRRSIRVNTLKITVADFLQLVApyrwqLTPVPWCEEG---FWIEREDEDDLPLGSaaehlSGLFYIQEASSMLPVaaL 125
Cdd:PRK14904 177 QAPLFGFRINRLKTTPEKFLAAPA-----DASVTFEKSGlpnFFLSKDFSLFEPFLK-----LGLVSVQNPTQALAC--L 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 126 FADGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRCGISNVALTHFDGRVFgaaLPEC-FDA 204
Cdd:PRK14904 245 LLNPQPGSTVLDLCAAPGGKSTFMAELMQNRGQITAVDRYPQKLEKIRSHASALGITIIETIEGDARSF---SPEEqPDA 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 205 ILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYSTCTLNRQENEEVVNGLLARYPQAVE 284
Cdd:PRK14904 322 ILLDAPCTGTGVLGRRAELRWKLTPEKLAELVGLQAELLDHAASLLKPGGVLVYATCSIEPEENELQIEAFLQRHPEFSA 401
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 1031301922 285 VVPLGSLFPQASEALTEEGFLHVFPQifDCEGF---FVARLRKTA 326
Cdd:PRK14904 402 EPSPGSLPEPFHEVAHPKGAILTLPG--EHEGFdggFAQRLRKNA 444
|
|
| rsmB |
TIGR00563 |
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. ... |
23-324 |
1.57e-36 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase; This protein is also known as sun protein. The reading frame was originally interpreted as two reading frames, fmu and fmv. The recombinant protein from E. coli was shown to methylate only C967 of small subunit (16S) ribosomal RNA and to produce only m5C at that position. The seed alignment is built from bacterial sequences only. Eukaryotic homologs include Nop2, a protein required for processing pre-rRNA, that is likely also a rRNA methyltransferase, although the fine specificity may differ. Cutoff scores are set to avoid treating archaeal and eukaroytic homologs automatically as functionally equivalent, although they may have very similar roles. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 273141 [Multi-domain] Cd Length: 426 Bit Score: 140.00 E-value: 1.57e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 23 PEEFLAQMRAAMPTHlsFDDFIAACQRPLRRSIRVNTLKITVADFLQLVApyrwqltpvpwcEEGFWIEREDEDD----L 98
Cdd:TIGR00563 138 PEWLVKRLQKAYPGQ--WQSICEANNQRPPMWLRINRTKHSRDEWLALLA------------EAGMKGFPHDLAPdavrL 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 99 PLGSAAEHL----SGLFYIQEASSMLPVAALfaDGQMPKRVMDVAAAPGSKTTQIAARMGnEGGILANEYSASRVKVLHA 174
Cdd:TIGR00563 204 ETPAAVHALpgfeEGWVTVQDASAQWVATWL--APQNEETILDACAAPGGKTTHILELAP-QAQVVALDIHEHRLKRVYE 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 175 NISRCGISNVALThFDGRVFG---AALPECFDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALR 251
Cdd:TIGR00563 281 NLKRLGLTIKAET-KDGDGRGpsqWAENEQFDRILLDAPCSATGVIRRHPDIKWLRKPRDIAELAELQSEILDAIWPLLK 359
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1031301922 252 PGGTLVYSTCTLNRQENEEVVNGLLARYPQAVEVVPLGSLFPQAsealteeGFLHVFPQIFDCEGFFVARLRK 324
Cdd:TIGR00563 360 TGGTLVYATCSVLPEENSEQIKAFLQEHPDFPFEKTGTPEQVRD-------GGLQILPHAEEGDGFFYAKLIK 425
|
|
| Methyltr_RsmF_N |
pfam17125 |
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the ... |
22-118 |
5.60e-36 |
|
N-terminal domain of 16S rRNA methyltransferase RsmF; This is the N-terminal domain of the RsmF methyl transferase. RsmF is a multi-site-specific methyltransferase that is responsible for the synthesis of three modifications on cytidines in 16S ribosomal RNA. The N-terminus is critical for stabilising the catalytic core of the enzyme.
Pssm-ID: 465356 [Multi-domain] Cd Length: 88 Bit Score: 128.36 E-value: 5.60e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 22 LPEEFLAQMRAAMPThlSFDDFIAACQRPLRRSIRVNTLKITVADFLQLVApyrWQLTPVPWCEEGFWIEREDEddlpLG 101
Cdd:pfam17125 1 LPEAFIERMRALLGD--EYEAFLAAYDEPRPVGLRVNTLKISVEEFLKLSP---FELEPVPWCEEGFYLEERPR----PG 71
|
90
....*....|....*..
gi 1031301922 102 SAAEHLSGLFYIQEASS 118
Cdd:pfam17125 72 KHPYHHAGLYYIQEPSA 88
|
|
| PRK10901 |
PRK10901 |
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB; |
17-324 |
1.40e-35 |
|
16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB;
Pssm-ID: 236790 [Multi-domain] Cd Length: 427 Bit Score: 137.24 E-value: 1.40e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 17 QNAVYL-PEEFLAQMRAAMPTHlsFDDFIAACQR--PLrrSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIER- 92
Cdd:PRK10901 137 PVARYNhPSWLIKRLKKAYPEQ--WQAILAANNQrpPM--WLRVNRRHHSRDAYLALLAEAGIEAFPHAVGPDAIRLETp 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 93 EDEDDLPlGSAAehlsGLFYIQEASSMLpvAALFADGQMPKRVMDVAAAPGSKTTQIAARMGNEGgILANEYSASRVKVL 172
Cdd:PRK10901 213 VPVHQLP-GFAE----GWVSVQDAAAQL--AATLLAPQNGERVLDACAAPGGKTAHILELAPQAQ-VVALDIDAQRLERV 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 173 HANISRCGIsNVALTHFDGRVFGAALP-ECFDAILLDAPCSGEGVVRKDPDaLKnW--SPESNAEIAVTQRELIDSAFHA 249
Cdd:PRK10901 285 RENLQRLGL-KATVIVGDARDPAQWWDgQPFDRILLDAPCSATGVIRRHPD-IK-WlrRPEDIAALAALQSEILDALWPL 361
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1031301922 250 LRPGGTLVYSTCTLNRQENEEVVNGLLARYPQAVEvVPLGSlfPQASEalteegfLHVFPQIFDCEGFFVARLRK 324
Cdd:PRK10901 362 LKPGGTLLYATCSILPEENEQQIKAFLARHPDAEL-LDTGT--PQQPG-------RQLLPGEEDGDGFFYALLIK 426
|
|
| PRK14903 |
PRK14903 |
16S rRNA methyltransferase B; Provisional |
21-288 |
9.14e-35 |
|
16S rRNA methyltransferase B; Provisional
Pssm-ID: 184896 [Multi-domain] Cd Length: 431 Bit Score: 135.00 E-value: 9.14e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 21 YLPEEFLAQMraampthLSFDdfiaacQRPLRRSIRVNTLKITVADFLQLVAPYRWQLTPVPWCEEGFWIEREDEddlPL 100
Cdd:PRK14903 145 FLPEEAVLRI-------MEWN------QEPLPTMLRVNSLAITREEVIKILAEEGTEAVPGKHSPFSLIVRKLGV---NM 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 101 GSAAEHLSGLFYIQ-EASSMLPvaaLFADGQMPKRVMDVAAAPGSKTTQIAARMGNEGGILANEYSASRVKVLHANISRC 179
Cdd:PRK14903 209 NDSRVIKDGLATVQgESSQIVP---LLMELEPGLRVLDTCAAPGGKTTAIAELMKDQGKILAVDISREKIQLVEKHAKRL 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 180 GISNVALTHFDGRVFGAALPECFDAILLDAPCSGEGVVRKDPDALKNWSPESNAEIAVTQRELIDSAFHALRPGGTLVYS 259
Cdd:PRK14903 286 KLSSIEIKIADAERLTEYVQDTFDRILVDAPCTSLGTARNHPEVLRRVNKEDFKKLSEIQLRIVSQAWKLLEKGGILLYS 365
|
250 260
....*....|....*....|....*....
gi 1031301922 260 TCTLNRQENEEVVNGLLARYPQaVEVVPL 288
Cdd:PRK14903 366 TCTVTKEENTEVVKRFVYEQKD-AEVIDI 393
|
|
| Methyltranf_PUA |
pfam13636 |
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two ... |
433-482 |
1.13e-11 |
|
RNA-binding PUA-like domain of methyltransferase RsmF; Methyltranf_PUA is the second of two C-terminal domains found on bacterial methyltransferase RsmF that modifies the 16S ribosomal RNA. It has some structural similarity to the RNA-binding PUA domains suggesting that it is involved in RNA recognition. It lies downstream of the catalytic centre of this methyltransferase, family pfam01189.
Pssm-ID: 433368 [Multi-domain] Cd Length: 50 Bit Score: 59.46 E-value: 1.13e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 1031301922 433 AEEWYRGRDIYPETLPQKDDAIVTYQGAPIGLAKKVGSRLKNSYPRELVR 482
Cdd:pfam13636 1 ALRYLRGETIELDGDLKAGWVLVTYDGFPLGWGKLLGGRLKNLYPKGLRI 50
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
134-259 |
8.13e-04 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 38.95 E-value: 8.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1031301922 134 RVMDVAAAPGSKTTQIAARMGNEggILANEYSASRVKVLHANISRCGISNVALTHFDGRVFGAALPECFDAILLDAPCSg 213
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGAR--VTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESFDVIISDPPLH- 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1031301922 214 egvvrkdpdalknWSPESnaeiavtQRELIDSAFHALRPGGTLVYS 259
Cdd:cd02440 78 -------------HLVED-------LARFLEEARRLLKPGGVLVLT 103
|
|
| |
