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Conserved domains on  [gi|1413839121|emb|SQL58147|]
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putative phage tail length tape measure protein [Escherichia coli]

Protein Classification

phage tail tape measure protein( domain architecture ID 11474537)

phage tail tape measure protein similar to Escherichia virus Lambda tape measure protein, also called minor tail protein H, which controls tail length by stopping tail tube protein polymerization

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TMP_2 pfam06791
Prophage tail length tape measure protein; This family represents a conserved region located ...
12-215 2.73e-87

Prophage tail length tape measure protein; This family represents a conserved region located towards the N-terminal end of prophage tail length tape measure protein (TMP). TMP is important for assembly of phage tails and involved in tail length determination. Mutated forms TMP cause tail fibres to be shortened.


:

Pssm-ID: 429120  Cd Length: 205  Bit Score: 275.36  E-value: 2.73e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  12 LSKTGMSAKQTAFAMRMLPAQMTDIVVGLSTGQSPFMVLMQQGGQLKDMFGGIGPAIKGVGSYVLGLINPFTLA--AAAV 89
Cdd:pfam06791   1 MEAAGKSAKQTAAAMRNLPAQFTDIATSLAGGQSPLTVLLQQGGQIKDMFGGIGPALKALGGYVLGLINPLTLAaaAAAV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  90 GVLGLAYYKGSQEQDEFNKSLILTGNQLGTTSGQLGDIAQRAGNAAdSTTGAAAAVLNQLVRSGKVASSSLEQVTTAIVK 169
Cdd:pfam06791  81 GALALAYYKGAEEADAFNKALILTGNAAGTTASQLAAMAEAIAAAG-GTQGAAAEALAALASTGKIGGEQLEGVIRAAAR 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1413839121 170 TSEVTGISTEQLVNDFNEIAKDPVSAISKLNDQYHFLTLATYNQIK 215
Cdd:pfam06791 160 MEKATGQSVDETAKDFAKLADDPLKAALKLNEQYHFLTAATYEQIK 205
tape_meas_lam_C super family cl36929
phage tail tape measure protein, lambda family; This model represents a relatively ...
448-784 6.03e-52

phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]


The actual alignment was detected with superfamily member TIGR01541:

Pssm-ID: 273681 [Multi-domain]  Cd Length: 332  Bit Score: 184.66  E-value: 6.03e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 448 ELVKWRQRIADLESRpssKLTQDQKSLLLHREEITALMEKnVAIEKNNrlikESAEITAWRDSLQASIDNRQQGYDIQIA 527
Cdd:TIGR01541   2 QLLLLTQQIADRKLK---KLNTADEKSLQSRSDEIIALIK-LEKLLEE----AEQKALEALKKLAEATASIRAQNKRQLD 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 528 GYGVGDKNQQRQQELLRIEHGYNNQRLQLERDYaDKSRGMSDHVFQEKMQALNDALEREKEIVRQKNEQLDIQAGDWVSG 607
Cdd:TIGR01541  74 RFGLGDKQRERLDARLQIDRTFRKQQRDLNKAM-TAKGLAGSDLYKEQLAAIKASLNEALAELHAYYAAEDALQGDWLAG 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 608 ASQGFNNWLDDTKDISEQIKSTTTQMFDGMTDALGDFVTTGKANFRSFATSVISDLSRIALKASITGIFDSI------SN 681
Cdd:TIGR01541 153 ARSGLADYGETATNVASATAQLATNAFGGMASNIAQMATTGKANFKSFAVSVLSDIADIIAKLAIAGLAQSIgsliggAA 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 682 SSSGGILGTIGSAISKFIPNAKGGVYeSPSLSTYSNGIYDSPQFFAFAKGAGVFGEAGPEAIMPLTRTSDGSLGVRAinS 761
Cdd:TIGR01541 233 SGGNSSSGAMASYGAAYVPNFAGGGY-TAGGGKYEPSGVVHPGEFVFTKGATRIGEGNLYAIMRGYAGGGGVLGVVA--A 309
                         330       340
                  ....*....|....*....|...
gi 1413839121 762 KSGNGGGDITYAPVYQITIQNDG 784
Cdd:TIGR01541 310 GSGGLGPNGMFGGETAISINNDG 332
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
278-546 1.60e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  278 SLDQKISDVLRQIDEIEKNTRPGVFGLGGIGDGGAQ--------NKRL--------ARLKQQLGVLQAEkIAQdvLNSSI 341
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEieqlleelNKKIkdlgeeeqLRVKEKIGELEAE-IAS--LERSI 310
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  342 NDYNKRQQEGIELRQRADAFSKQYQTR----EQQRASELAKLEKLKNQYS--KEEYNNLIAQINERYKDPKQPKAKgySD 415
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEieelEREIEEERKRRDKLTEEYAelKEELEDLRAELEEVDKEFAETRDE--LK 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  416 DAAQRMIDHLNQQNALLSSQAELTVKLSSSEQELVKWRQRIADLESRpsskltqdqkslllHREEITALMEKNVAIEKNN 495
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK--------------INELEEEKEDKALEIKKQE 454
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1413839121  496 RLIKESAEItawRDSLQASIDNRQQGYDIqiagygVGDKNQQRQQELLRIE 546
Cdd:TIGR02169  455 WKLEQLAAD---LSKYEQELYDLKEEYDR------VEKELSKLQRELAEAE 496
 
Name Accession Description Interval E-value
TMP_2 pfam06791
Prophage tail length tape measure protein; This family represents a conserved region located ...
12-215 2.73e-87

Prophage tail length tape measure protein; This family represents a conserved region located towards the N-terminal end of prophage tail length tape measure protein (TMP). TMP is important for assembly of phage tails and involved in tail length determination. Mutated forms TMP cause tail fibres to be shortened.


Pssm-ID: 429120  Cd Length: 205  Bit Score: 275.36  E-value: 2.73e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  12 LSKTGMSAKQTAFAMRMLPAQMTDIVVGLSTGQSPFMVLMQQGGQLKDMFGGIGPAIKGVGSYVLGLINPFTLA--AAAV 89
Cdd:pfam06791   1 MEAAGKSAKQTAAAMRNLPAQFTDIATSLAGGQSPLTVLLQQGGQIKDMFGGIGPALKALGGYVLGLINPLTLAaaAAAV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  90 GVLGLAYYKGSQEQDEFNKSLILTGNQLGTTSGQLGDIAQRAGNAAdSTTGAAAAVLNQLVRSGKVASSSLEQVTTAIVK 169
Cdd:pfam06791  81 GALALAYYKGAEEADAFNKALILTGNAAGTTASQLAAMAEAIAAAG-GTQGAAAEALAALASTGKIGGEQLEGVIRAAAR 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1413839121 170 TSEVTGISTEQLVNDFNEIAKDPVSAISKLNDQYHFLTLATYNQIK 215
Cdd:pfam06791 160 MEKATGQSVDETAKDFAKLADDPLKAALKLNEQYHFLTAATYEQIK 205
tape_meas_lam_C TIGR01541
phage tail tape measure protein, lambda family; This model represents a relatively ...
448-784 6.03e-52

phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273681 [Multi-domain]  Cd Length: 332  Bit Score: 184.66  E-value: 6.03e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 448 ELVKWRQRIADLESRpssKLTQDQKSLLLHREEITALMEKnVAIEKNNrlikESAEITAWRDSLQASIDNRQQGYDIQIA 527
Cdd:TIGR01541   2 QLLLLTQQIADRKLK---KLNTADEKSLQSRSDEIIALIK-LEKLLEE----AEQKALEALKKLAEATASIRAQNKRQLD 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 528 GYGVGDKNQQRQQELLRIEHGYNNQRLQLERDYaDKSRGMSDHVFQEKMQALNDALEREKEIVRQKNEQLDIQAGDWVSG 607
Cdd:TIGR01541  74 RFGLGDKQRERLDARLQIDRTFRKQQRDLNKAM-TAKGLAGSDLYKEQLAAIKASLNEALAELHAYYAAEDALQGDWLAG 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 608 ASQGFNNWLDDTKDISEQIKSTTTQMFDGMTDALGDFVTTGKANFRSFATSVISDLSRIALKASITGIFDSI------SN 681
Cdd:TIGR01541 153 ARSGLADYGETATNVASATAQLATNAFGGMASNIAQMATTGKANFKSFAVSVLSDIADIIAKLAIAGLAQSIgsliggAA 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 682 SSSGGILGTIGSAISKFIPNAKGGVYeSPSLSTYSNGIYDSPQFFAFAKGAGVFGEAGPEAIMPLTRTSDGSLGVRAinS 761
Cdd:TIGR01541 233 SGGNSSSGAMASYGAAYVPNFAGGGY-TAGGGKYEPSGVVHPGEFVFTKGATRIGEGNLYAIMRGYAGGGGVLGVVA--A 309
                         330       340
                  ....*....|....*....|...
gi 1413839121 762 KSGNGGGDITYAPVYQITIQNDG 784
Cdd:TIGR01541 310 GSGGLGPNGMFGGETAISINNDG 332
Tape_meas_lam_C pfam09718
Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively ...
602-676 1.21e-24

Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively well-conserved region near the C terminus of the tape measure protein of a lambda and related phage. The protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behaviour is attributed to proteins from distantly related or unrelated families in other phage.


Pssm-ID: 430770 [Multi-domain]  Cd Length: 76  Bit Score: 97.73  E-value: 1.21e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1413839121 602 GDWVSGASQGFNNWLDDTKDISEQIKSTTTQMFDGMTDALGDFVTTGKANFRSFATSVISDLSRIALKASITGIF 676
Cdd:pfam09718   1 GDWTDGAKRALAEYAEEASNAAGQVEEAFTSAFSGMEDALVEFVTTGKLNFSDFADSIIADLARIAARQAITGPL 75
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
220-821 7.07e-23

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 103.92  E-value: 7.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 220 EGNQQEAARIATEEYSSSMIQRTNQIKENLGYLETAWKAVADSAKWAWDSMLDIGRETSLDQKISDVLRQIDEIEKNTRP 299
Cdd:COG5281     2 AALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 300 GVFGLGGIGDGGAQNKRLARLKQQLGVLQAEKIAQDVLNSSINDYNKRQQEGIELRQRADAFSKQYQtREQQRASELAKL 379
Cdd:COG5281    82 AALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAK-AAAAAAAAAALA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 380 EKLKNQYSKEEYNNLIAQINERYKDPKQPKAKGYSDDAAQRMIDHLNQQNALLSSQAELTVKLSSSEQELVKWRQRIADL 459
Cdd:COG5281   161 AAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 460 ESRPSSKLTQDQKSLLLHREEITALMEKNVAIEKNNRLIKESAEITAWRDSLQASIDNRQQGYDIQIAGYGVGDKNQQRQ 539
Cdd:COG5281   241 SAAAQALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 540 QELLRIEhgynNQRLQLERDYADKSRGMSDHVFQEKMQALNDALEREKEIVRQKNEQLDIQAGDWVSGASQGFNNWLDDT 619
Cdd:COG5281   321 AQALRAA----AQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSA 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 620 KDISEQIKSTTTQMFDGMTDALGDFVTTGKANFRSFATSVISDLSRIALKASITGIfdsisnsssGGILGTIGSAISKFI 699
Cdd:COG5281   397 TNVAAQVAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIADALANAALASAA---------DALGGALAGALGGLF 467
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 700 PNAKG-----GVYESPSLSTYSNGIYDSPQFFAFAKGAGVFGEAGPEAIMPLTRTSDGSLGVRAInskSGNGGGDITYAP 774
Cdd:COG5281   468 GGGGGaaagaAVYAGALGPFASGGVVSGPTFFAMAGGAGLMGEAGPEAIMPLARGADGRLGVAAA---GGGGGAAVVVNI 544
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 1413839121 775 VYQITIQNDGQNGEIGPQAIKALMGMVDQRVQGNLLNMRRDGGMLSG 821
Cdd:COG5281   545 TTPDAAGFRRSQAQIAAQVARAVARGGRGLAAAAAAAGAADGGAGGG 591
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
278-546 1.60e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  278 SLDQKISDVLRQIDEIEKNTRPGVFGLGGIGDGGAQ--------NKRL--------ARLKQQLGVLQAEkIAQdvLNSSI 341
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEieqlleelNKKIkdlgeeeqLRVKEKIGELEAE-IAS--LERSI 310
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  342 NDYNKRQQEGIELRQRADAFSKQYQTR----EQQRASELAKLEKLKNQYS--KEEYNNLIAQINERYKDPKQPKAKgySD 415
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEieelEREIEEERKRRDKLTEEYAelKEELEDLRAELEEVDKEFAETRDE--LK 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  416 DAAQRMIDHLNQQNALLSSQAELTVKLSSSEQELVKWRQRIADLESRpsskltqdqkslllHREEITALMEKNVAIEKNN 495
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK--------------INELEEEKEDKALEIKKQE 454
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1413839121  496 RLIKESAEItawRDSLQASIDNRQQGYDIqiagygVGDKNQQRQQELLRIE 546
Cdd:TIGR02169  455 WKLEQLAAD---LSKYEQELYDLKEEYDR------VEKELSKLQRELAEAE 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
312-503 1.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 312 AQNKRLARLKQQLGVLQAE-KIAQDVLNSSINDYNKRQQEGIELRQRADAFSKQYQTREQQRASELAKLEKLKNQYS--- 387
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEiAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAelr 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 388 ---KEEYNNLIAQINERYKDPKQPKAKGY--SDDAAQ-----RMIDHLNQQ---------------NALLSSQAELTVKL 442
Cdd:COG4942    97 aelEAQKEELAELLRALYRLGRQPPLALLlsPEDFLDavrrlQYLKYLAPArreqaeelradlaelAALRAELEAERAEL 176
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1413839121 443 SSSEQELVKWRQRIADLESRPSSKLTQDQKSLLLHREEITALMEKNVAIEKN-NRLIKESAE 503
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALiARLEAEAAA 238
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
241-601 1.78e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  241 RTNQIKENLGYLETAWKAVADSAKwawdsmldiGRETSLDQKISDVLRQIDEIEknTRPGVFGLGGIGDGGAQNKRL--- 317
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELN---------GELSAADAAVAKDRSELEALE--DQHGAFLDADIETAAADQEQLpsw 352
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  318 --------ARLKQQLGVLQAEKIAQDVLNSSINDYNKRQQEGIELRQradafSKQYQTREQQRASELAKLEKLKNQYsKE 389
Cdd:pfam12128  353 qselenleERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKL-----AKIREARDRQLAVAEDDLQALESEL-RE 426
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  390 EYNNLIAQINE---RYK---------------DPKQPKAKGYSDDAAQRMIDHLNQQNA-LLSSQAELTVKLSSSEQELV 450
Cdd:pfam12128  427 QLEAGKLEFNEeeyRLKsrlgelklrlnqataTPELLLQLENFDERIERAREEQEAANAeVERLQSELRQARKRRDQASE 506
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  451 KWRQRIADLESRPS--------------------SKLTQDQK--------SLLLHREEITALMEKNVAIEKNN----RLI 498
Cdd:pfam12128  507 ALRQASRRLEERQSaldelelqlfpqagtllhflRKEAPDWEqsigkvisPELLHRTDLDPEVWDGSVGGELNlygvKLD 586
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  499 KESAEITAWRDS---LQASID----------NRQQGYDIQIAGYGVGDKNQQRQQELLRieHGYNNQRLQLERdyadksr 565
Cdd:pfam12128  587 LKRIDVPEWAASeeeLRERLDkaeealqsarEKQAAAEEQLVQANGELEKASREETFAR--TALKNARLDLRR------- 657
                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1413839121  566 gMSDHVFQEKMQaLNDALEREKEIVRQKNEQLDIQA 601
Cdd:pfam12128  658 -LFDEKQSEKDK-KNKALAERKDSANERLNSLEAQL 691
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
98-281 5.47e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 40.42  E-value: 5.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121   98 KGSQEQDEFNKSLILTGNQLGTTSGQLGDIAQRAGNAADSTTGAAAAV--LNQLVRSGKVASSSLEQVTTAIVKTSEVTg 175
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVqsLIREIKDAKEQDSPLETFLEKDQQEKEEL- 928
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  176 ISTEqlvNDFNEIAKDPVSAISKLNDQYHFLTLATYNQIKALQDEGNQQEAARIATEEYS-SSMIQRTNQIKENLGYLET 254
Cdd:TIGR00606  929 ISSK---ETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQlEECEKHQEKINEDMRLMRQ 1005
                          170       180
                   ....*....|....*....|....*..
gi 1413839121  255 AWKAVADSAKWAWDSMLDIGRETSLDQ 281
Cdd:TIGR00606 1006 DIDTQKIQERWLQDNLTLRKRENELKE 1032
 
Name Accession Description Interval E-value
TMP_2 pfam06791
Prophage tail length tape measure protein; This family represents a conserved region located ...
12-215 2.73e-87

Prophage tail length tape measure protein; This family represents a conserved region located towards the N-terminal end of prophage tail length tape measure protein (TMP). TMP is important for assembly of phage tails and involved in tail length determination. Mutated forms TMP cause tail fibres to be shortened.


Pssm-ID: 429120  Cd Length: 205  Bit Score: 275.36  E-value: 2.73e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  12 LSKTGMSAKQTAFAMRMLPAQMTDIVVGLSTGQSPFMVLMQQGGQLKDMFGGIGPAIKGVGSYVLGLINPFTLA--AAAV 89
Cdd:pfam06791   1 MEAAGKSAKQTAAAMRNLPAQFTDIATSLAGGQSPLTVLLQQGGQIKDMFGGIGPALKALGGYVLGLINPLTLAaaAAAV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  90 GVLGLAYYKGSQEQDEFNKSLILTGNQLGTTSGQLGDIAQRAGNAAdSTTGAAAAVLNQLVRSGKVASSSLEQVTTAIVK 169
Cdd:pfam06791  81 GALALAYYKGAEEADAFNKALILTGNAAGTTASQLAAMAEAIAAAG-GTQGAAAEALAALASTGKIGGEQLEGVIRAAAR 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1413839121 170 TSEVTGISTEQLVNDFNEIAKDPVSAISKLNDQYHFLTLATYNQIK 215
Cdd:pfam06791 160 MEKATGQSVDETAKDFAKLADDPLKAALKLNEQYHFLTAATYEQIK 205
tape_meas_lam_C TIGR01541
phage tail tape measure protein, lambda family; This model represents a relatively ...
448-784 6.03e-52

phage tail tape measure protein, lambda family; This model represents a relatively well-conserved region near the C-terminus of the tape measure protein of a lambda and related phage. This protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behavior is attributed to proteins from distantly related or unrelated families in other phage. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 273681 [Multi-domain]  Cd Length: 332  Bit Score: 184.66  E-value: 6.03e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 448 ELVKWRQRIADLESRpssKLTQDQKSLLLHREEITALMEKnVAIEKNNrlikESAEITAWRDSLQASIDNRQQGYDIQIA 527
Cdd:TIGR01541   2 QLLLLTQQIADRKLK---KLNTADEKSLQSRSDEIIALIK-LEKLLEE----AEQKALEALKKLAEATASIRAQNKRQLD 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 528 GYGVGDKNQQRQQELLRIEHGYNNQRLQLERDYaDKSRGMSDHVFQEKMQALNDALEREKEIVRQKNEQLDIQAGDWVSG 607
Cdd:TIGR01541  74 RFGLGDKQRERLDARLQIDRTFRKQQRDLNKAM-TAKGLAGSDLYKEQLAAIKASLNEALAELHAYYAAEDALQGDWLAG 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 608 ASQGFNNWLDDTKDISEQIKSTTTQMFDGMTDALGDFVTTGKANFRSFATSVISDLSRIALKASITGIFDSI------SN 681
Cdd:TIGR01541 153 ARSGLADYGETATNVASATAQLATNAFGGMASNIAQMATTGKANFKSFAVSVLSDIADIIAKLAIAGLAQSIgsliggAA 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 682 SSSGGILGTIGSAISKFIPNAKGGVYeSPSLSTYSNGIYDSPQFFAFAKGAGVFGEAGPEAIMPLTRTSDGSLGVRAinS 761
Cdd:TIGR01541 233 SGGNSSSGAMASYGAAYVPNFAGGGY-TAGGGKYEPSGVVHPGEFVFTKGATRIGEGNLYAIMRGYAGGGGVLGVVA--A 309
                         330       340
                  ....*....|....*....|...
gi 1413839121 762 KSGNGGGDITYAPVYQITIQNDG 784
Cdd:TIGR01541 310 GSGGLGPNGMFGGETAISINNDG 332
Tape_meas_lam_C pfam09718
Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively ...
602-676 1.21e-24

Lambda phage tail tape-measure protein (Tape_meas_lam_C); This represents a relatively well-conserved region near the C terminus of the tape measure protein of a lambda and related phage. The protein, which controls phage tail length, is typically about 1000 residues in length. Both low-complexity sequence and insertion/deletion events appear common in this family. Mutational studies suggest a ruler or template role in the determination of phage tail length. Similar behaviour is attributed to proteins from distantly related or unrelated families in other phage.


Pssm-ID: 430770 [Multi-domain]  Cd Length: 76  Bit Score: 97.73  E-value: 1.21e-24
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1413839121 602 GDWVSGASQGFNNWLDDTKDISEQIKSTTTQMFDGMTDALGDFVTTGKANFRSFATSVISDLSRIALKASITGIF 676
Cdd:pfam09718   1 GDWTDGAKRALAEYAEEASNAAGQVEEAFTSAFSGMEDALVEFVTTGKLNFSDFADSIIADLARIAARQAITGPL 75
COG5281 COG5281
Phage-related minor tail protein [Mobilome: prophages, transposons];
220-821 7.07e-23

Phage-related minor tail protein [Mobilome: prophages, transposons];


Pssm-ID: 444092 [Multi-domain]  Cd Length: 603  Bit Score: 103.92  E-value: 7.07e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 220 EGNQQEAARIATEEYSSSMIQRTNQIKENLGYLETAWKAVADSAKWAWDSMLDIGRETSLDQKISDVLRQIDEIEKNTRP 299
Cdd:COG5281     2 AALAAAAALAAAAAAAAASAAAAAAAAALAAAAAAAAAAAGLAAAAAAAAAASLAAAAAAAALAAAAAAAAAAAAADALA 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 300 GVFGLGGIGDGGAQNKRLARLKQQLGVLQAEKIAQDVLNSSINDYNKRQQEGIELRQRADAFSKQYQtREQQRASELAKL 379
Cdd:COG5281    82 AALAEDAAAAAAAAEAALAALAAAALALAAAALAEAALAAAAAAAAAAAAAAAAAAAAAAAAAEAAK-AAAAAAAAAALA 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 380 EKLKNQYSKEEYNNLIAQINERYKDPKQPKAKGYSDDAAQRMIDHLNQQNALLSSQAELTVKLSSSEQELVKWRQRIADL 459
Cdd:COG5281   161 AAAAAAAAAAAAAAAAAALAAASAAAAAAAAKAAAEAAAEAAAAAEAAAAAAAAAAEAAAAEAQALAAAALAEQAALAAA 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 460 ESRPSSKLTQDQKSLLLHREEITALMEKNVAIEKNNRLIKESAEITAWRDSLQASIDNRQQGYDIQIAGYGVGDKNQQRQ 539
Cdd:COG5281   241 SAAAQALAALAAAAAAAALALAAAAELALTAQAEAAAAAAAAAAAAAQAAEAAAAAAEAQALAAAAAAAAAQLAAAAAAA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 540 QELLRIEhgynNQRLQLERDYADKSRGMSDHVFQEKMQALNDALEREKEIVRQKNEQLDIQAGDWVSGASQGFNNWLDDT 619
Cdd:COG5281   321 AQALRAA----AQALAALAQRALAAAALAAAAQEAALAAAAAALQAALEAAAAAAAAELAAAGDWAAGAKAALAEYADSA 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 620 KDISEQIKSTTTQMFDGMTDALGDFVTTGKANFRSFATSVISDLSRIALKASITGIfdsisnsssGGILGTIGSAISKFI 699
Cdd:COG5281   397 TNVAAQVAQAATSAFSGLTDALAGAVTTGKLLFDALASSIASIADALANAALASAA---------DALGGALAGALGGLF 467
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 700 PNAKG-----GVYESPSLSTYSNGIYDSPQFFAFAKGAGVFGEAGPEAIMPLTRTSDGSLGVRAInskSGNGGGDITYAP 774
Cdd:COG5281   468 GGGGGaaagaAVYAGALGPFASGGVVSGPTFFAMAGGAGLMGEAGPEAIMPLARGADGRLGVAAA---GGGGGAAVVVNI 544
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*..
gi 1413839121 775 VYQITIQNDGQNGEIGPQAIKALMGMVDQRVQGNLLNMRRDGGMLSG 821
Cdd:COG5281   545 TTPDAAGFRRSQAQIAAQVARAVARGGRGLAAAAAAAGAADGGAGGG 591
COG1340 COG1340
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
314-593 1.87e-05

Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];


Pssm-ID: 440951 [Multi-domain]  Cd Length: 297  Bit Score: 47.21  E-value: 1.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 314 NKRLARLKQQLGVLQAE----KIAQDVLNSSINDY-NKRQqegiELRQRADAFSKQYQTREQQRASELAKLEKLKNQYS- 387
Cdd:COG1340     7 SSSLEELEEKIEELREEieelKEKRDELNEELKELaEKRD----ELNAQVKELREEAQELREKRDELNEKVKELKEERDe 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 388 -KEEYNNLIAQINERYKDPKQPKAKGYSDDAAQRMIDHL--NQQNALLSSQAeltvklsssEQELVkwrQRIADLESRPS 464
Cdd:COG1340    83 lNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERLewRQQTEVLSPEE---------EKELV---EKIKELEKELE 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 465 SKLTQDQKSLLLhREEITALMEKNVAIEKNNRLIKESAE--------ITAW---RDSLQASIDNRQQgydiqiagygvgd 533
Cdd:COG1340   151 KAKKALEKNEKL-KELRAELKELRKEAEEIHKKIKELAEeaqelheeMIELykeADELRKEADELHK------------- 216
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 534 KNQQRQQELLRIEHGYNNQRLQLeRDYADKSRGMSDHVFQEKMQALNDALEREKEIVRQK 593
Cdd:COG1340   217 EIVEAQEKADELHEEIIELQKEL-RELRKELKKLRKKQRALKREKEKEELEEKAEEIFEK 275
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
315-601 1.28e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 1.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 315 KRLARLKQQLGVLQAEKIAQDvLNSSINDYNKRQQEGIELRQRADAFSKQYQTREQQRASELAKLEKLKNQYSK--EEYN 392
Cdd:COG1196   213 ERYRELKEELKELEAELLLLK-LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqAEEY 291
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 393 NLIAQINERYKDpkqpkakgySDDAAQRMIDHLNQQNALLSSQAELTVKLSSSEQELVKWRQRIADLESRPSSKLTQDQK 472
Cdd:COG1196   292 ELLAELARLEQD---------IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 473 SLLLHREEITALMEKNVAIEKNNRLIKESAEITAWRDSLQASIDNRQQGYDIQIAgygvgdKNQQRQQELLRIEHGYNNQ 552
Cdd:COG1196   363 AEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLE------RLEEELEELEEALAELEEE 436
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1413839121 553 RLQLERDYADKSRGMSDHVfQEKMQALNDALEREKEIVRQKNEQLDIQA 601
Cdd:COG1196   437 EEEEEEALEEAAEEEAELE-EEEEALLELLAELLEEAALLEAALAELLE 484
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
278-546 1.60e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 1.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  278 SLDQKISDVLRQIDEIEKNTRPGVFGLGGIGDGGAQ--------NKRL--------ARLKQQLGVLQAEkIAQdvLNSSI 341
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEieqlleelNKKIkdlgeeeqLRVKEKIGELEAE-IAS--LERSI 310
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  342 NDYNKRQQEGIELRQRADAFSKQYQTR----EQQRASELAKLEKLKNQYS--KEEYNNLIAQINERYKDPKQPKAKgySD 415
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEieelEREIEEERKRRDKLTEEYAelKEELEDLRAELEEVDKEFAETRDE--LK 388
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  416 DAAQRMIDHLNQQNALLSSQAELTVKLSSSEQELVKWRQRIADLESRpsskltqdqkslllHREEITALMEKNVAIEKNN 495
Cdd:TIGR02169  389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK--------------INELEEEKEDKALEIKKQE 454
                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1413839121  496 RLIKESAEItawRDSLQASIDNRQQGYDIqiagygVGDKNQQRQQELLRIE 546
Cdd:TIGR02169  455 WKLEQLAAD---LSKYEQELYDLKEEYDR------VEKELSKLQRELAEAE 496
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
312-503 1.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 1.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 312 AQNKRLARLKQQLGVLQAE-KIAQDVLNSSINDYNKRQQEGIELRQRADAFSKQYQTREQQRASELAKLEKLKNQYS--- 387
Cdd:COG4942    17 AQADAAAEAEAELEQLQQEiAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAelr 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 388 ---KEEYNNLIAQINERYKDPKQPKAKGY--SDDAAQ-----RMIDHLNQQ---------------NALLSSQAELTVKL 442
Cdd:COG4942    97 aelEAQKEELAELLRALYRLGRQPPLALLlsPEDFLDavrrlQYLKYLAPArreqaeelradlaelAALRAELEAERAEL 176
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1413839121 443 SSSEQELVKWRQRIADLESRPSSKLTQDQKSLLLHREEITALMEKNVAIEKN-NRLIKESAE 503
Cdd:COG4942   177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALiARLEAEAAA 238
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
241-601 1.78e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 1.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  241 RTNQIKENLGYLETAWKAVADSAKwawdsmldiGRETSLDQKISDVLRQIDEIEknTRPGVFGLGGIGDGGAQNKRL--- 317
Cdd:pfam12128  284 TSAELNQLLRTLDDQWKEKRDELN---------GELSAADAAVAKDRSELEALE--DQHGAFLDADIETAAADQEQLpsw 352
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  318 --------ARLKQQLGVLQAEKIAQDVLNSSINDYNKRQQEGIELRQradafSKQYQTREQQRASELAKLEKLKNQYsKE 389
Cdd:pfam12128  353 qselenleERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKL-----AKIREARDRQLAVAEDDLQALESEL-RE 426
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  390 EYNNLIAQINE---RYK---------------DPKQPKAKGYSDDAAQRMIDHLNQQNA-LLSSQAELTVKLSSSEQELV 450
Cdd:pfam12128  427 QLEAGKLEFNEeeyRLKsrlgelklrlnqataTPELLLQLENFDERIERAREEQEAANAeVERLQSELRQARKRRDQASE 506
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  451 KWRQRIADLESRPS--------------------SKLTQDQK--------SLLLHREEITALMEKNVAIEKNN----RLI 498
Cdd:pfam12128  507 ALRQASRRLEERQSaldelelqlfpqagtllhflRKEAPDWEqsigkvisPELLHRTDLDPEVWDGSVGGELNlygvKLD 586
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  499 KESAEITAWRDS---LQASID----------NRQQGYDIQIAGYGVGDKNQQRQQELLRieHGYNNQRLQLERdyadksr 565
Cdd:pfam12128  587 LKRIDVPEWAASeeeLRERLDkaeealqsarEKQAAAEEQLVQANGELEKASREETFAR--TALKNARLDLRR------- 657
                          410       420       430
                   ....*....|....*....|....*....|....*.
gi 1413839121  566 gMSDHVFQEKMQaLNDALEREKEIVRQKNEQLDIQA 601
Cdd:pfam12128  658 -LFDEKQSEKDK-KNKALAERKDSANERLNSLEAQL 691
Taxilin pfam09728
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ...
334-503 3.69e-03

Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.


Pssm-ID: 462861 [Multi-domain]  Cd Length: 302  Bit Score: 40.32  E-value: 3.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 334 QDVLNSSINDYNKRQQEGIELRQRADAFSKQYQTREQQRASELAKLEkLKNQYSKEEYNNLIAQINERYKDPKQPKAKGY 413
Cdd:pfam09728 116 QDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKTKE-LEVQLAEAKLQQATEEEEKKAQEKEVAKAREL 194
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121 414 sddaaQRMIDHLNQQNALLSSQAELTVK--------LSSSEQELVKWRQRIADLesrpSSKLTQDQKslllhreEITALM 485
Cdd:pfam09728 195 -----KAQVQTLSETEKELREQLNLYVEkfeefqdtLNKSNEVFTTFKKEMEKM----SKKIKKLEK-------ENLTWK 258
                         170
                  ....*....|....*...
gi 1413839121 486 EKNvaiEKNNRLIKESAE 503
Cdd:pfam09728 259 RKW---EKSNKALLEMAE 273
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
98-281 5.47e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 40.42  E-value: 5.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121   98 KGSQEQDEFNKSLILTGNQLGTTSGQLGDIAQRAGNAADSTTGAAAAV--LNQLVRSGKVASSSLEQVTTAIVKTSEVTg 175
Cdd:TIGR00606  850 KLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVqsLIREIKDAKEQDSPLETFLEKDQQEKEEL- 928
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1413839121  176 ISTEqlvNDFNEIAKDPVSAISKLNDQYHFLTLATYNQIKALQDEGNQQEAARIATEEYS-SSMIQRTNQIKENLGYLET 254
Cdd:TIGR00606  929 ISSK---ETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQlEECEKHQEKINEDMRLMRQ 1005
                          170       180
                   ....*....|....*....|....*..
gi 1413839121  255 AWKAVADSAKWAWDSMLDIGRETSLDQ 281
Cdd:TIGR00606 1006 DIDTQKIQERWLQDNLTLRKRENELKE 1032
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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