|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
47-741 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 1151.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 47 ALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEE---GRHLAIEAPTGVGKTLSYLIPGIAIAREEQKT 123
Cdd:PRK11747 1 MLTDALKAQIRQAYKALQEQLPGFIPRAGQRQMIAEVAKTLAGEYlkdGRILVIEAGTGVGKTLSYLLAGIPIARAEKKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 124 LVVSTANVALQDQIYSKDLPLLKKIIP-DLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCA 202
Cdd:PRK11747 81 LVISTATVALQEQLVSKDLPLLLKISGlDFKFTLAKGRGRYVCPRKLAALASDEGTQQDLLLFLDDELTPPDEEEQKLLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 203 KLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAME--SEA 280
Cdd:PRK11747 161 RLAKALATGKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLElgGGV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 281 VLPDPKNLLLVLDEGHHLPDVARDALEMSAEI--TAPWYRLQLDLFTKLVATCMEqfrpktiPPLAIPERLNAHCEELYE 358
Cdd:PRK11747 241 VLPDPENLLYVLDEGHHLPDVARDHFAASAELkgTADWLEKLLKLLTKLVALIME-------PPLALPERLNAHCEELRE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 359 LIASLNNILNLYMPAG-QEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSE--KTGSHDIVRLHRLILQMN 435
Cdd:PRK11747 314 LLASLNQILNLFLPAGgEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEamKTGKIDIVRLERLLLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 436 RALGMFEAQSKLWRLAS-LAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFS 514
Cdd:PRK11747 394 RALGRLEALSKLWRLAAkEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 515 RLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPsiDNEEQHIAEMAAFFRKQVESKKhlGMLVLFASGRAMQR 594
Cdd:PRK11747 474 RFQEQSGLPEKDGDRFLALPSPFDYPNQGKLVIPKMRAEP--DNEEAHTAEMAEFLPELLEKHK--GSLVLFASRRQMQK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 595 FLDYV-TDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGE 673
Cdd:PRK11747 550 VADLLpRDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAE 629
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1415711384 674 WLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPE 741
Cdd:PRK11747 630 WLKSRGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIEE 697
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
58-751 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 573.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 58 AWYKALQEQIPDFIPRAPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQI 137
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARAL--AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 138 YSKDLPLLKKIIP-DLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELtpnnqeeqkrcaklkgDLDTYKWDGL 216
Cdd:COG1199 79 VEKDLPLLRKALGlPLRVALLKGRSNYLCLRRLEQALQEGDDLDDEELLLARIL----------------AWASETWTGD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 217 RDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMES-EAVLPDpkNLLLVLDEG 295
Cdd:COG1199 143 RDELPLPEDDELWRQVTSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALgEELLPE--DDVLIIDEA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 296 HHLPDVARDALemSAEITAPWYRLQLDLFTKLVAtcmeqfRPKTIPPLAIPERLNAHCEELYELIaslnnilnlympaGQ 375
Cdd:COG1199 221 HNLPDRARDMF--SAELSSRSLLRLLRELRKLGL------RPGLKKLLDLLERLREALDDLFLAL-------------EE 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 376 EAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTgshDIVRLHRLILQMNRALGMFeaqsklwrlasLAQ 455
Cdd:COG1199 280 EEELRLALGELPDEPEELLEALDALRDALEALAEALEEELERLA---ELDALLERLEELLFALARF-----------LRI 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 456 SSGAPVTKWATREERegqlHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAgdRFVALDS 535
Cdd:COG1199 346 AEDEGYVRWLEREGG----DVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDA--RTLSLPS 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 536 PFNHCEQGKIVIPRMRVEPSidNEEQHIAEMAAFFRKQVESKKHlGMLVLFASGRAMQRFLDYVTD-LRLMLLVQGDQPR 614
Cdd:COG1199 420 PFDYENQALLYVPRDLPRPS--DRDGYLEAIAEAIAELLEASGG-NTLVLFTSYRALEQVAELLRErLDIPVLVQGDGSR 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 615 YRLVELHRKrvanGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFN 694
Cdd:COG1199 497 EALLERFRE----GGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVIK 572
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1415711384 695 LIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPEVPEGIVKKKE 751
Cdd:COG1199 573 LKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTRPEELRAFLERLD 629
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
73-750 |
1.99e-46 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 178.07 E-value: 1.99e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 73 RAPQRQMIADVAKTLAGEEgrHLAIEAPTGVGKTLSYLIPGIAIAREEqKTLVVSTANVALQDQIYSKDLPLLKKIIP-D 151
Cdd:TIGR01407 247 RPEQLKLAELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAITE-KPVVISTNTKVLQSQLLEKDIPLLNEILNfK 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 152 LKFTAAFGRGRYVcprnltalasteptqqDLLAFlddELTPNNQEEQKRCAKLK------------GDLDTYKWDGLRDH 219
Cdd:TIGR01407 324 INAALIKGKSNYL----------------SLGKF---SQILKDNTDNYEFNIFKmqvlvwltetetGDLDELNLKGGNKM 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 220 tdiaidddLWRRLSTDKAscLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPdPKNLLLVLDEGHHLP 299
Cdd:TIGR01407 385 --------FFAQVRHDGN--LSKKDLFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNPELF-PSFRDLIIDEAHHLP 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 300 DVARDALEMSAEITAPWYrlQLDLFTKL----VATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYmpagq 375
Cdd:TIGR01407 454 DIAENQLQEELDYADIKY--QIDLIGKGeneqLLKRIQQLEKQEILEKLFDFETKDILKDLQAILDKLNKLLQIF----- 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 376 eaehrfamgelpdevleicqrlakltemlrglAELFLNDLSEktgshdivrlhrLILQMNRALGMFeaqsklWRLAslaQ 455
Cdd:TIGR01407 527 --------------------------------SELSHKTVDQ------------LRKFDLALKDDF------KNIE---Q 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 456 SSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKagdRFVALD- 534
Cdd:TIGR01407 554 SLKEGHTSWISIENLQQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFPQLLGLTDV---HFNTIEp 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 535 SPFNHCEQGKIVIPRMRV---EPSIDNEEQHIAEMAAFFRKQVESKkhlgMLVLFASGRAMQRFLDYVTDLRLM----LL 607
Cdd:TIGR01407 631 TPLNYAENQRVLIPTDAPaiqNKSLEEYAQEIASYIIEITAITSPK----ILVLFTSYEMLHMVYDMLNELPEFegyeVL 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 608 VQG-DQPRYRLVelhrKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQ 686
Cdd:TIGR01407 707 AQGiNGSRAKIK----KRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEGKNPFYDY 782
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1415711384 687 SLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFP----IEQPEVPEGIVKKK 750
Cdd:TIGR01407 783 VLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLPEYLqvkgDILGELLEAIKEFL 850
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
573-735 |
1.43e-45 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 160.42 E-value: 1.43e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 573 QVESKKHLGMLVLFASGRAMQRFLDYVTD----LRLMLLVQ-GDQPRYRLVELHRKRvanGERSVLVGLQ--SFAEGLDL 645
Cdd:pfam13307 2 RLLKVIPGGVLVFFPSYSYLEKVAERLKEsgleKGIEIFVQpGEGSREKLLEEFKKK---GKGAVLFGVCggSFSEGIDF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 646 KGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYG 725
Cdd:pfam13307 79 PGDLLRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYG 158
|
170
....*....|
gi 1415711384 726 KRLLDALPVF 735
Cdd:pfam13307 159 KLLPKWLPPG 168
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
590-721 |
2.55e-30 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 116.22 E-value: 2.55e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 590 RAMQRFLDYVTD-----LRLMLLVQGDQPRYRlVELHRKRVANGER--SVLVGLQS--FAEGLDLKGDLLSQVHIHKIAF 660
Cdd:smart00491 2 RYLEQVVEYWKEngileINKPVFIEGKDSGET-EELLEKYSAACEArgALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1415711384 661 PPIDSPVVITEGEWLKS-LNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLT 721
Cdd:smart00491 81 PNPDSPILRARLEYLDEkGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
640-718 |
2.16e-05 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 45.29 E-value: 2.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 640 AEGLDLKGDLLSQVHIHKIAFPPIDSPVVItegewLKSLNRYPFEVQSLPSASFNLIQQ--------VGRLIRSHGCWGE 711
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILK-----LKMDDLEYLRDKGLLTGEDWYTFQamravnqaIGRAIRHKNDYGA 151
|
....*..
gi 1415711384 712 VVIYDKR 718
Cdd:cd18788 152 IVLLDKR 158
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
47-741 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 1151.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 47 ALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEE---GRHLAIEAPTGVGKTLSYLIPGIAIAREEQKT 123
Cdd:PRK11747 1 MLTDALKAQIRQAYKALQEQLPGFIPRAGQRQMIAEVAKTLAGEYlkdGRILVIEAGTGVGKTLSYLLAGIPIARAEKKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 124 LVVSTANVALQDQIYSKDLPLLKKIIP-DLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCA 202
Cdd:PRK11747 81 LVISTATVALQEQLVSKDLPLLLKISGlDFKFTLAKGRGRYVCPRKLAALASDEGTQQDLLLFLDDELTPPDEEEQKLLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 203 KLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAME--SEA 280
Cdd:PRK11747 161 RLAKALATGKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLElgGGV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 281 VLPDPKNLLLVLDEGHHLPDVARDALEMSAEI--TAPWYRLQLDLFTKLVATCMEqfrpktiPPLAIPERLNAHCEELYE 358
Cdd:PRK11747 241 VLPDPENLLYVLDEGHHLPDVARDHFAASAELkgTADWLEKLLKLLTKLVALIME-------PPLALPERLNAHCEELRE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 359 LIASLNNILNLYMPAG-QEAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSE--KTGSHDIVRLHRLILQMN 435
Cdd:PRK11747 314 LLASLNQILNLFLPAGgEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEamKTGKIDIVRLERLLLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 436 RALGMFEAQSKLWRLAS-LAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFS 514
Cdd:PRK11747 394 RALGRLEALSKLWRLAAkEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 515 RLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPsiDNEEQHIAEMAAFFRKQVESKKhlGMLVLFASGRAMQR 594
Cdd:PRK11747 474 RFQEQSGLPEKDGDRFLALPSPFDYPNQGKLVIPKMRAEP--DNEEAHTAEMAEFLPELLEKHK--GSLVLFASRRQMQK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 595 FLDYV-TDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGE 673
Cdd:PRK11747 550 VADLLpRDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAE 629
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1415711384 674 WLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPE 741
Cdd:PRK11747 630 WLKSRGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIEE 697
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
58-751 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 573.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 58 AWYKALQEQIPDFIPRAPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQI 137
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARAL--AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 138 YSKDLPLLKKIIP-DLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELtpnnqeeqkrcaklkgDLDTYKWDGL 216
Cdd:COG1199 79 VEKDLPLLRKALGlPLRVALLKGRSNYLCLRRLEQALQEGDDLDDEELLLARIL----------------AWASETWTGD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 217 RDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMES-EAVLPDpkNLLLVLDEG 295
Cdd:COG1199 143 RDELPLPEDDELWRQVTSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALgEELLPE--DDVLIIDEA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 296 HHLPDVARDALemSAEITAPWYRLQLDLFTKLVAtcmeqfRPKTIPPLAIPERLNAHCEELYELIaslnnilnlympaGQ 375
Cdd:COG1199 221 HNLPDRARDMF--SAELSSRSLLRLLRELRKLGL------RPGLKKLLDLLERLREALDDLFLAL-------------EE 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 376 EAEHRFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTgshDIVRLHRLILQMNRALGMFeaqsklwrlasLAQ 455
Cdd:COG1199 280 EEELRLALGELPDEPEELLEALDALRDALEALAEALEEELERLA---ELDALLERLEELLFALARF-----------LRI 345
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 456 SSGAPVTKWATREERegqlHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAgdRFVALDS 535
Cdd:COG1199 346 AEDEGYVRWLEREGG----DVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDA--RTLSLPS 419
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 536 PFNHCEQGKIVIPRMRVEPSidNEEQHIAEMAAFFRKQVESKKHlGMLVLFASGRAMQRFLDYVTD-LRLMLLVQGDQPR 614
Cdd:COG1199 420 PFDYENQALLYVPRDLPRPS--DRDGYLEAIAEAIAELLEASGG-NTLVLFTSYRALEQVAELLRErLDIPVLVQGDGSR 496
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 615 YRLVELHRKrvanGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFN 694
Cdd:COG1199 497 EALLERFRE----GGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVIK 572
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 1415711384 695 LIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPIEQPEVPEGIVKKKE 751
Cdd:COG1199 573 LKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTRPEELRAFLERLD 629
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
60-737 |
2.42e-66 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 236.77 E-value: 2.42e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 60 YKALQEQIPDFIPRAPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYS 139
Cdd:PRK08074 246 EEKLSLAMPKYEKREGQQEMMKEVYTAL--RDSEHALIEAGTGTGKSLAYLLPAAYFAKKKEEPVVISTYTIQLQQQLLE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 140 KDLPLLKKIIPdLKFTAAF--GRGRYVCPRNLTALASTEPTQQD-------LLAFLDDELTpnnqeeqkrcaklkGDLDT 210
Cdd:PRK08074 324 KDIPLLQKIFP-FPVEAALlkGRSHYLCLRKFEQALQEEDDNYDvaltkaqLLVWLTETET--------------GDLDE 388
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 211 ykwdgLRDHTDIAIdddLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEA-VLPDPKNLl 289
Cdd:PRK08074 389 -----LNLPSGGKL---LWNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEEpLLPSYEHI- 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 290 lVLDEGHHLPDVARDALEMSA---EITAPWYRL----QLDLFTKLvATCMEQFRPKTIPPLA-IPERLNAHCEELYELIA 361
Cdd:PRK08074 460 -IIDEAHHFEEAASRHLGEQFsymSFQLLLSRLgtleEDGLLSKL-AKLFKKSDQASRSSFRdLDESLKELKFEADELFQ 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 362 SLNNILNLYMPAGQEAEHRFAM------GELPDEVLEICQRL----AKLTEMLRGLAELFLNDLSEKtgSHDIVRLHRLI 431
Cdd:PRK08074 538 MLRSFVLKRKKQEQNGRLIYRYntesekGKLWDAITELANRLcydlRDLLTLLEAQKKELQEKMESE--SAFLTGEYAHL 615
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 432 LQMNRalgmFEAQsklwrLASLAQSSGAPVTKWATREEReGQLHLWF-HCVGIRVSDQLERLLWRSIPHIIVTSATLRSL 510
Cdd:PRK08074 616 IDLLE----KMAQ-----LLQLLFEEDPDYVTWIEIDAK-GAINATRlYAQPVEVAERLADEFFAKKKSVILTSATLTVN 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 511 NSFSRLQEMSGLkEKAGDRFVALDSPFNHCEQGKIVIPR-MrvePSI--DNEEQHIAEMAAFFRKQVESKKhlG-MLVLF 586
Cdd:PRK08074 686 GSFDYIIERLGL-EDFYPRTLQIPSPFSYEEQAKLMIPTdM---PPIkdVPIEEYIEEVAAYIAKIAKATK--GrMLVLF 759
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 587 ASGRAMQRFLDYVTDL----RLMLLVQGDQ--PRYRLVelhrKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAF 660
Cdd:PRK08074 760 TSYEMLKKTYYNLKNEeeleGYVLLAQGVSsgSRARLT----KQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPF 835
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1415711384 661 PPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFPI 737
Cdd:PRK08074 836 APPDQPVMEAKSEWAKEQGENPFQELSLPQAVLRFKQGFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVPV 912
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
73-750 |
1.99e-46 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 178.07 E-value: 1.99e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 73 RAPQRQMIADVAKTLAGEEgrHLAIEAPTGVGKTLSYLIPGIAIAREEqKTLVVSTANVALQDQIYSKDLPLLKKIIP-D 151
Cdd:TIGR01407 247 RPEQLKLAELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAITE-KPVVISTNTKVLQSQLLEKDIPLLNEILNfK 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 152 LKFTAAFGRGRYVcprnltalasteptqqDLLAFlddELTPNNQEEQKRCAKLK------------GDLDTYKWDGLRDH 219
Cdd:TIGR01407 324 INAALIKGKSNYL----------------SLGKF---SQILKDNTDNYEFNIFKmqvlvwltetetGDLDELNLKGGNKM 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 220 tdiaidddLWRRLSTDKAscLNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPdPKNLLLVLDEGHHLP 299
Cdd:TIGR01407 385 --------FFAQVRHDGN--LSKKDLFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNPELF-PSFRDLIIDEAHHLP 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 300 DVARDALEMSAEITAPWYrlQLDLFTKL----VATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYmpagq 375
Cdd:TIGR01407 454 DIAENQLQEELDYADIKY--QIDLIGKGeneqLLKRIQQLEKQEILEKLFDFETKDILKDLQAILDKLNKLLQIF----- 526
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 376 eaehrfamgelpdevleicqrlakltemlrglAELFLNDLSEktgshdivrlhrLILQMNRALGMFeaqsklWRLAslaQ 455
Cdd:TIGR01407 527 --------------------------------SELSHKTVDQ------------LRKFDLALKDDF------KNIE---Q 553
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 456 SSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKagdRFVALD- 534
Cdd:TIGR01407 554 SLKEGHTSWISIENLQQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFPQLLGLTDV---HFNTIEp 630
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 535 SPFNHCEQGKIVIPRMRV---EPSIDNEEQHIAEMAAFFRKQVESKkhlgMLVLFASGRAMQRFLDYVTDLRLM----LL 607
Cdd:TIGR01407 631 TPLNYAENQRVLIPTDAPaiqNKSLEEYAQEIASYIIEITAITSPK----ILVLFTSYEMLHMVYDMLNELPEFegyeVL 706
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 608 VQG-DQPRYRLVelhrKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQ 686
Cdd:TIGR01407 707 AQGiNGSRAKIK----KRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEGKNPFYDY 782
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1415711384 687 SLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDALPVFP----IEQPEVPEGIVKKK 750
Cdd:TIGR01407 783 VLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLPEYLqvkgDILGELLEAIKEFL 850
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
573-735 |
1.43e-45 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 160.42 E-value: 1.43e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 573 QVESKKHLGMLVLFASGRAMQRFLDYVTD----LRLMLLVQ-GDQPRYRLVELHRKRvanGERSVLVGLQ--SFAEGLDL 645
Cdd:pfam13307 2 RLLKVIPGGVLVFFPSYSYLEKVAERLKEsgleKGIEIFVQpGEGSREKLLEEFKKK---GKGAVLFGVCggSFSEGIDF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 646 KGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYG 725
Cdd:pfam13307 79 PGDLLRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYG 158
|
170
....*....|
gi 1415711384 726 KRLLDALPVF 735
Cdd:pfam13307 159 KLLPKWLPPG 168
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
590-721 |
2.55e-30 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 116.22 E-value: 2.55e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 590 RAMQRFLDYVTD-----LRLMLLVQGDQPRYRlVELHRKRVANGER--SVLVGLQS--FAEGLDLKGDLLSQVHIHKIAF 660
Cdd:smart00491 2 RYLEQVVEYWKEngileINKPVFIEGKDSGET-EELLEKYSAACEArgALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1415711384 661 PPIDSPVVITEGEWLKS-LNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLT 721
Cdd:smart00491 81 PNPDSPILRARLEYLDEkGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| PRK07246 |
PRK07246 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
97-732 |
4.48e-19 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain] Cd Length: 820 Bit Score: 92.44 E-value: 4.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 97 IEAPTGVGKTLSYLIPgiAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKI----IPDLKftaafGRGRYVcprNLTAL 172
Cdd:PRK07246 269 IEAQTGIGKTYGYLLP--LLAQSDQRQIIVSVPTKILQDQIMAEEVKAIQEVfhidCHSLK-----GPQNYL---KLDAF 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 173 ASTEPTQQD----------LLAFLDdELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRlSTDKAsclnr 242
Cdd:PRK07246 339 YDSLQQNDDnrlvnrykmqLLVWLT-ETETGDLDEIKQKQRYAAYFDQLKHDGNLSQSSLFYDYDFWKR-SYEKA----- 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 243 ncyyyrecpffvarreiQEAEVVVANHALVMAAMESeavlpDP---KNLLLVLDEGHHLpdvardalemsaeitapwyRL 319
Cdd:PRK07246 412 -----------------KTARLLITNHAYFLTRVQD-----DKdfaRNKVLVFDEAQKL-------------------ML 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 320 QLDLFTKlvatcmeqfrpktipplaipERLNahceeLYELIASLNNILNlympagqeaehrfamGELPdeVLEicQRLAK 399
Cdd:PRK07246 451 QLEQLSR--------------------HQLN-----ITSFLQTIQKALS---------------GPLP--LLQ--KRLLE 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 400 -LTEMLRGLAELFLNDLSEKTGSHDIVRLHRLI-------LQMNRALgmFEAQSKLWRLASLAQSSGAPVTKWATREER- 470
Cdd:PRK07246 487 sISFELLQLSEQFYQGKERQLIHDSLSRLHQYFselevagFQELQAF--FATAEGDYWLESEKQSEKRVTYLNSASKAFt 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 471 EGQLHLWFHCVGIRVSDQLErllwrsiphiIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFnhceqgkiviprm 550
Cdd:PRK07246 565 HFSQLLPETCKTYFVSATLQ----------ISPRVSLADLLGFEEYLFHKIEKDKKQDQLVVVDQDM------------- 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 551 rvePSID--NEEQHIAEMAaffrKQVESKKHLG--MLVLFASGRAMQRFLDYVTDLRLMLLVQG-DQPRYRLvelhRKRV 625
Cdd:PRK07246 622 ---PLVTetSDEVYAEEIA----KRLEELKQLQqpILVLFNSKKHLLAVSDLLDQWQVSHLAQEkNGTAYNI----KKRF 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 626 ANGERSVLVGLQSFAEGLDL-KGDLLSQVhihkIAFPPIDSPvvitEGEWLKSLNRY-------PFEVQSLPSASFNLIQ 697
Cdd:PRK07246 691 DRGEQQILLGLGSFWEGVDFvQADRMIEV----ITRLPFDNP----EDPFVKKMNQYllqegknPFYDYFLPMTILRLKQ 762
|
650 660 670
....*....|....*....|....*....|....*
gi 1415711384 698 QVGRLIRSHGCWGEVVIYDKRLLTKNYGKRLLDAL 732
Cdd:PRK07246 763 AIGRTMRREDQKSAVLILDRRILTKSYGKQILASL 797
|
|
| DEXDc2 |
smart00488 |
DEAD-like helicases superfamily; |
70-313 |
1.48e-08 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214693 [Multi-domain] Cd Length: 289 Bit Score: 56.62 E-value: 1.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 70 FIPRAPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSyLIPGI---AIAREEQKTLVVstanVALQDQIYSKdlplLK 146
Cdd:smart00488 7 YEPYPIQYEFMEELKRVL--DRGKIGILESPTGTGKTLS-LLCLTltwLRSFPERIQKIK----LIYLSRTVSE----IE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 147 KIIPDLKFTAAFGRGRYVCPRNLTA--LASTEPTQQDllaFLDDELTPN-----NQEEQK----------RCAKLK-GDL 208
Cdd:smart00488 76 KRLEELRKLMQKVEYESDEESEKQAqlLHELGREKPK---VLGLSLTSRknlclNPEVRTlkqnglvvdeVCRSLTaSKA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 209 DTYKWDGLRDHTDI--AIDDDLWRR-------LSTDKASCLNRNCyyyRECPFFVARREIQEAEVVVANHALVMAAMESE 279
Cdd:smart00488 153 RKYRYENPKVERCPfyENTEFLLVRdllpaevYDIEDLLELGKRL---GGCPYFASRKAIEFANVVVLPYQYLLDPKIRQ 229
|
250 260 270
....*....|....*....|....*....|....
gi 1415711384 280 AVLPDPKNLLLVLDEGHHLPDVARDALemSAEIT 313
Cdd:smart00488 230 ALSIELKDSIVIFDEAHNLDNVCISAL--SSELS 261
|
|
| rad3 |
TIGR00604 |
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are ... |
73-728 |
1.48e-06 |
|
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273169 [Multi-domain] Cd Length: 705 Bit Score: 51.64 E-value: 1.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 73 RAPQRQMIADVAKTLagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVstanvalqdqIY-SKDLPLLKKIIPD 151
Cdd:TIGR00604 12 YPEQRSYMRDLKRSL--DRGDEAILEMPSGTGKTISLLSLILAYQQEKPEVRKI----------IYaSRTHSQLEQATEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 152 LKFTAAFGRGRYVCPRNLTALASTEptQQDL-LAFLDDELTPNNQEEQKrCAKLKGDL------------------DTYK 212
Cdd:TIGR00604 80 LRKLMSYRTPRIGEESPVSGLSLAS--RKNLcLHPEVSKERQGKVVNGK-CIKLTVSKikeqrtekpnvescefyeNFDE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 213 WDGLRDHTDIAIDD-----DLWRRLSTdkasclnrncyyyreCPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKN 287
Cdd:TIGR00604 157 LREVEDLLLSEIMDiedlvEYGELLGL---------------CPYFATRKMLPFANIVLLPYQYLLDPKIRSAVSIELKD 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 288 LLLVLDEGHHLPDVARDALemSAEIT----------------------APWYRLQLDLFTKLV--------ATCMEQF-- 335
Cdd:TIGR00604 222 SIVIFDEAHNLDNVCISSL--SSNLSvrslkrcskeiaeyfekieerkEVDARKLLDELQKLVeglkqedlLTDEDIFla 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 336 ---RPKTIPPLAIPERLNahceelyelIASLNNI-LNLYMPAGQEAE--HRFaMGELPDEVLEICQRLAKLTEMLRGLAE 409
Cdd:TIGR00604 300 npvLPKEVLPEAVPGNIR---------IAEIFLHkLSRYLEYLKDALkvLGV-VSELPDAFLEHLKEKTFIDRPLRFCSE 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 410 LFLNDLSEKTGSHdivrlhrlilqmnraLGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQL 489
Cdd:TIGR00604 370 RLSNLLRELEITH---------------PEDFSALVLLFTFATLVLTYTNGFLEGIEPYENKTVPNPILKFMCLDPSIAL 434
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 490 ERLLWRsIPHIIVTSATLRSLNSFSRLqemsglkekAGDRFVALDSPfNHceqgkiVIPRMRVEPSIDNEEQHIAEMAAF 569
Cdd:TIGR00604 435 KPLFER-VRSVILASGTLSPLDAFPRN---------LGFNPVSQDSP-TH------ILKRENLLTLIVTRGSDQVPLSST 497
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 570 FRKQ-------------VESKKHL--GMLVLFASGRAMQRF---------LDYVTDLRLMLLVQGD-QPRYRLVELHRKR 624
Cdd:TIGR00604 498 FEIRndpslvrnlgellVEFSKIIpdGIVVFFPSYSYLENIvstwkemgiLENIEKKKLIFVETKDaQETSDALERYKQA 577
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 625 VANGERSVLVGLQ--SFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVITEGEWLKSL-----NRYPFEVQSLPSASfnliQ 697
Cdd:TIGR00604 578 VSEGRGAVLLSVAggKVSEGIDFCDDLGRAVIMVGIPYEYTESRILLARLEFLRDQypireNQDFYEFDAMRAVN----Q 653
|
730 740 750
....*....|....*....|....*....|.
gi 1415711384 698 QVGRLIRSHGCWGEVVIYDKRLLTKNYGKRL 728
Cdd:TIGR00604 654 AIGRVIRHKDDYGSIVLLDKRYARSNKRKKL 684
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
640-718 |
2.16e-05 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 45.29 E-value: 2.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 640 AEGLDLKGDLLSQVHIHKIAFPPIDSPVVItegewLKSLNRYPFEVQSLPSASFNLIQQ--------VGRLIRSHGCWGE 711
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILK-----LKMDDLEYLRDKGLLTGEDWYTFQamravnqaIGRAIRHKNDYGA 151
|
....*..
gi 1415711384 712 VVIYDKR 718
Cdd:cd18788 152 IVLLDKR 158
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
70-174 |
1.22e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 44.02 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 70 FIPRAPQRQMIADVAktlagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQ--KTLVVStANVALQDQIYSKdlplLKK 147
Cdd:smart00487 7 EPLRPYQKEAIEALL-----SGLRDVILAAPTGSGKTLAALLPALEALKRGKggRVLVLV-PTRELAEQWAEE----LKK 76
|
90 100
....*....|....*....|....*..
gi 1415711384 148 IIPDLKFTAAFGRGRYVCPRNLTALAS 174
Cdd:smart00487 77 LGPSLGLKVVGLYGGDSKREQLRKLES 103
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
73-161 |
2.59e-04 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 42.23 E-value: 2.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 73 RAPQRQMIADVaktlagEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQ---KTLVVS-TanVALQDQIYSKdlplLKKI 148
Cdd:pfam00270 1 TPIQAEAIPAI------LEGRDVLVQAPTGSGKTLAFLLPALEALDKLDngpQALVLApT--RELAEQIYEE----LKKL 68
|
90
....*....|...
gi 1415711384 149 IPDLKFTAAFGRG 161
Cdd:pfam00270 69 GKGLGLKVASLLG 81
|
|
| DEXHc_Hrq1-like |
cd17923 |
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a ... |
88-160 |
2.04e-03 |
|
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. Hrq1 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350681 [Multi-domain] Cd Length: 182 Bit Score: 39.88 E-value: 2.04e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1415711384 88 AGEEGRHLAIEAPTGVGKTLSYLIPGI-AIAREEQ-KTLVVSTANvAL-QDQIYSkdlplLKKIIPDLKFTAAFGR 160
Cdd:cd17923 11 AARAGRSVVVTTGTASGKSLCYQLPILeALLRDPGsRALYLYPTK-ALaQDQLRS-----LRELLEQLGLGIRVAT 80
|
|
| DEXHc_RE |
cd17926 |
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ... |
72-140 |
2.67e-03 |
|
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350684 [Multi-domain] Cd Length: 146 Bit Score: 38.83 E-value: 2.67e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 72 PRAPQRQMIAdvaKTLAGEEGRHLAIEAPTGVGKTLSYLipGIAIAREEQKTL-VVSTanVALQDQIYSK 140
Cdd:cd17926 1 LRPYQEEALE---AWLAHKNNRRGILVLPTGSGKTLTAL--ALIAYLKELRTLiVVPT--DALLDQWKER 63
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
92-167 |
5.59e-03 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 38.15 E-value: 5.59e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1415711384 92 GRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPdlkfTAAFGRGRYVCPR 167
Cdd:cd00046 1 GENVLITAPTGSGKTLAALLAALLLLLKKGKKVLVLVPTKALALQTAERLRELFGPGIR----VAVLVGGSSAEER 72
|
|
| DEADc |
cd00268 |
DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family ... |
91-114 |
5.71e-03 |
|
DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350669 [Multi-domain] Cd Length: 196 Bit Score: 38.58 E-value: 5.71e-03
|
| Lhr |
COG1201 |
Lhr-like helicase [Replication, recombination and repair]; |
72-108 |
6.65e-03 |
|
Lhr-like helicase [Replication, recombination and repair];
Pssm-ID: 440814 [Multi-domain] Cd Length: 850 Bit Score: 40.09 E-value: 6.65e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1415711384 72 PRAPQRQMIADVAktlageEGRHLAIEAPTGVGKTLS 108
Cdd:COG1201 25 PTPPQREAWPAIA------AGESTLLIAPTGSGKTLA 55
|
|
| DEADc_DDX51 |
cd17956 |
DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by ... |
60-112 |
6.71e-03 |
|
DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by regulating multiple signalling pathways. Mammalian DEAD box protein Ddx51 acts in 3' end maturation of 28S rRNA by promoting the release of U8 snoRNA.It is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350714 [Multi-domain] Cd Length: 231 Bit Score: 38.77 E-value: 6.71e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 1415711384 60 YKALQEQ-IPDFIPraPQRQMIADVAKTLAGEEGRH---LAIEAPTGVGKTLSYLIP 112
Cdd:cd17956 2 LKNLQNNgITSAFP--VQAAVIPWLLPSSKSTPPYRpgdLCVSAPTGSGKTLAYVLP 56
|
|
| Cas3 |
COG1203 |
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; ... |
42-122 |
6.83e-03 |
|
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]; CRISPR-Cas type I system-associated endonuclease/helicase Cas3 is part of the Pathway/BioSystem: CRISPR-Cas system
Pssm-ID: 440816 [Multi-domain] Cd Length: 535 Bit Score: 39.68 E-value: 6.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 42 SGFLMALTAALKAQIAAWYKALQEQIPDFI-PRAPQRQMIADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREE 120
Cdd:COG1203 96 SANFDMARQALDHLLAERLERLLPKKSKPRtPINPLQNEALELALEAAEEEPGLFILTAPTGGGKTEAALLFALRLAAKH 175
|
..
gi 1415711384 121 QK 122
Cdd:COG1203 176 GG 177
|
|
| DEADc_DDX55 |
cd17960 |
DEAD-box helicase domain of DEAD box protein 55; DDX55 is a member of the DEAD-box helicases, ... |
96-153 |
7.43e-03 |
|
DEAD-box helicase domain of DEAD box protein 55; DDX55 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350718 [Multi-domain] Cd Length: 202 Bit Score: 38.33 E-value: 7.43e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1415711384 96 AIEAPTGVGKTLSYLIPGIAI--AREEQKT------LVVSTANvALQDQIYSKDLPLLKKIIPDLK 153
Cdd:cd17960 31 VVEAVTGSGKTLAFLIPVLEIllKRKANLKkgqvgaLIISPTR-ELATQIYEVLQSFLEHHLPKLK 95
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
56-140 |
9.29e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 39.24 E-value: 9.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1415711384 56 IAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAGEEGRHLaIEAPTGVGKTLSylipGIAIARE---EQKTLVVSTaNVA 132
Cdd:COG1061 65 AEALEAGDEASGTSFELRPYQQEALEALLAALERGGGRGL-VVAPTGTGKTVL----ALALAAEllrGKRVLVLVP-RRE 138
|
....*...
gi 1415711384 133 LQDQIYSK 140
Cdd:COG1061 139 LLEQWAEE 146
|
|
| |
