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Conserved domains on  [gi|1429757499|emb|SSI23756|]
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serine transporter [Klebsiella pneumoniae]

Protein Classification

amino acid permease( domain architecture ID 11435282)

amino acid permease similar to Schizosaccharomyces pombe vacuolar amino acid transporter 5 that is involved in the vacuolar uptake of histidine, glutamate, tyrosine, arginine, lysine, and serine, and required for sporulation

Gene Ontology:  GO:0006865

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
1-409 1.87e-90

Amino acid permease [Amino acid transport and metabolism];


:

Pssm-ID: 440576  Cd Length: 401  Bit Score: 278.56  E-value: 1.87e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499   1 MSKIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiaPGTGITGAVNHY 80
Cdd:COG0814     4 KAMKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSSP--PGADITTVVEEY 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499  81 YGKKIGNLITGLYFLAFFVVVLIYAVAITNSLAEQVAHRTPMTPGlRALLSLGVVLVLNLIFLMGRQVTIKVMGFLVFPL 160
Cdd:COG0814    82 LGKGGGILIGLLYFFLLYPLLLAYISGGGNILASFLVNQLGLTIP-RWLLSLIFILVLGAIVWLGTRLVDRVNRILVFPK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 161 IACFLFLSLYLIRDWHPEHLTSQMqfSPQTLHQVWISIPVMVFAFSHTPIISTFAIDQQEKhgdlaMGKCKKIMKVAYTI 240
Cdd:COG0814   161 IIAFLLLSLYLIPHWNLANLLNSA--LPSYLKYLWLALPVLLTSFGFHPIIPSLVKYYRKD-----AKKLRRAILIGSLI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 241 ICASVLFFVFSCLLAIPATYIETARDQGVTILSALSMVPGAPgWLAVTGIIVAVVAMSKSFLGTYFGVIEGASEIVKssl 320
Cdd:COG0814   234 PLVIYLFWVFSCLGSLPPEEFAEAKAQNISLLSALANVFNSP-LISYLGPLFAFFAIATSFLGVYLGLFDFLADLFK--- 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 321 gllgvRKSRAFNRAMSILLVSAFTFAVCFINPNAISMIYAISGPLIAMILFIMPTLSTWLIPALKP--YRSVG----NAI 394
Cdd:COG0814   310 -----KKKSKKGRLKTALLTFLPPWIVALLNPSIFILALGYAGPIIAILLFILPALLVWKVRARFPlkYRVPGgklsLIF 384

                         410
                  ....*....|....*
gi 1429757499 395 TLVVGLLCVSVMFFG 409
Cdd:COG0814   385 VILFGLLAISAQILS 399
 
Name Accession Description Interval E-value
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
1-409 1.87e-90

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440576  Cd Length: 401  Bit Score: 278.56  E-value: 1.87e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499   1 MSKIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiaPGTGITGAVNHY 80
Cdd:COG0814     4 KAMKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSSP--PGADITTVVEEY 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499  81 YGKKIGNLITGLYFLAFFVVVLIYAVAITNSLAEQVAHRTPMTPGlRALLSLGVVLVLNLIFLMGRQVTIKVMGFLVFPL 160
Cdd:COG0814    82 LGKGGGILIGLLYFFLLYPLLLAYISGGGNILASFLVNQLGLTIP-RWLLSLIFILVLGAIVWLGTRLVDRVNRILVFPK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 161 IACFLFLSLYLIRDWHPEHLTSQMqfSPQTLHQVWISIPVMVFAFSHTPIISTFAIDQQEKhgdlaMGKCKKIMKVAYTI 240
Cdd:COG0814   161 IIAFLLLSLYLIPHWNLANLLNSA--LPSYLKYLWLALPVLLTSFGFHPIIPSLVKYYRKD-----AKKLRRAILIGSLI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 241 ICASVLFFVFSCLLAIPATYIETARDQGVTILSALSMVPGAPgWLAVTGIIVAVVAMSKSFLGTYFGVIEGASEIVKssl 320
Cdd:COG0814   234 PLVIYLFWVFSCLGSLPPEEFAEAKAQNISLLSALANVFNSP-LISYLGPLFAFFAIATSFLGVYLGLFDFLADLFK--- 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 321 gllgvRKSRAFNRAMSILLVSAFTFAVCFINPNAISMIYAISGPLIAMILFIMPTLSTWLIPALKP--YRSVG----NAI 394
Cdd:COG0814   310 -----KKKSKKGRLKTALLTFLPPWIVALLNPSIFILALGYAGPIIAILLFILPALLVWKVRARFPlkYRVPGgklsLIF 384

                         410
                  ....*....|....*
gi 1429757499 395 TLVVGLLCVSVMFFG 409
Cdd:COG0814   385 VILFGLLAISAQILS 399
PRK13629 PRK13629
threonine/serine transporter TdcC; Provisional
 5-403 3.71e-59

threonine/serine transporter TdcC; Provisional


Pssm-ID: 184191  Cd Length: 443  Bit Score: 198.92  E-value: 3.71e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499   5 WSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiAPGTGITGAVNHYYGKK 84
Cdd:PRK13629   17 WRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGS-NPSGNITETVEEHFGKT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499  85 IGNLITGLYFLAFFVVVLIYAVAITNSLAEQVAHRTPMTPGLRALLSLGVVLVLNLIFLMGRQVTIKVMGFLVFPLIACF 164
Cdd:PRK13629   96 GGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 165 LFLSLYLIRDWHPEHLT----SQMQFSPQ--TLHQVWISIPVMVFAFSHTPIISTFAIDQQEKH-----GDLAMGKCKKI 233
Cdd:PRK13629  176 VLISLSLIPYWNSAVIDqvdlGSLSLTGHdgILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYekdfgRDFTERKCSQI 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 234 MKVAYTIICASVLFFVFSCLLAIPATYIETARDQGVTILSAL----SMVPGAPGWLAVT----GIIVAVVAMSKSFLGTY 305
Cdd:PRK13629  256 ISRASMLMVAVVMFFAFSCLFTLSPQNMAEAKAQNIPVLSYLanhfASMTGTKSTFAITleyaASIIALVAIFKSFFGHY 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 306 FGVIEGASEIVkSSLGLLGVRKSRAFNR--AMSILLVSAFTFAVCFINPNAISMIYAISGPLIAMILFIMPTLSTWLIPA 383
Cdd:PRK13629  336 LGTLEGLNGLI-LKFGYKGDKTKVSLGKlnTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPS 414

                         410       420
                  ....*....|....*....|.
gi 1429757499 384 LKPYRS-VGNAITLVVGLLCV 403
Cdd:PRK13629  415 LAKYRGrLDNVFVTVIGLLTI 435
 
Name Accession Description Interval E-value
SdaC COG0814
Amino acid permease [Amino acid transport and metabolism];
1-409 1.87e-90

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440576  Cd Length: 401  Bit Score: 278.56  E-value: 1.87e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499   1 MSKIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiaPGTGITGAVNHY 80
Cdd:COG0814     4 KAMKWRKSDLGWVLLIAGTAIGAGMLALPIAAGGGGFWPSLLLLLLAWPLMYLSHLLLLEVNLSSP--PGADITTVVEEY 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499  81 YGKKIGNLITGLYFLAFFVVVLIYAVAITNSLAEQVAHRTPMTPGlRALLSLGVVLVLNLIFLMGRQVTIKVMGFLVFPL 160
Cdd:COG0814    82 LGKGGGILIGLLYFFLLYPLLLAYISGGGNILASFLVNQLGLTIP-RWLLSLIFILVLGAIVWLGTRLVDRVNRILVFPK 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 161 IACFLFLSLYLIRDWHPEHLTSQMqfSPQTLHQVWISIPVMVFAFSHTPIISTFAIDQQEKhgdlaMGKCKKIMKVAYTI 240
Cdd:COG0814   161 IIAFLLLSLYLIPHWNLANLLNSA--LPSYLKYLWLALPVLLTSFGFHPIIPSLVKYYRKD-----AKKLRRAILIGSLI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 241 ICASVLFFVFSCLLAIPATYIETARDQGVTILSALSMVPGAPgWLAVTGIIVAVVAMSKSFLGTYFGVIEGASEIVKssl 320
Cdd:COG0814   234 PLVIYLFWVFSCLGSLPPEEFAEAKAQNISLLSALANVFNSP-LISYLGPLFAFFAIATSFLGVYLGLFDFLADLFK--- 309

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 321 gllgvRKSRAFNRAMSILLVSAFTFAVCFINPNAISMIYAISGPLIAMILFIMPTLSTWLIPALKP--YRSVG----NAI 394
Cdd:COG0814   310 -----KKKSKKGRLKTALLTFLPPWIVALLNPSIFILALGYAGPIIAILLFILPALLVWKVRARFPlkYRVPGgklsLIF 384

                         410
                  ....*....|....*
gi 1429757499 395 TLVVGLLCVSVMFFG 409
Cdd:COG0814   385 VILFGLLAISAQILS 399
PRK13629 PRK13629
threonine/serine transporter TdcC; Provisional
 5-403 3.71e-59

threonine/serine transporter TdcC; Provisional


Pssm-ID: 184191  Cd Length: 443  Bit Score: 198.92  E-value: 3.71e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499   5 WSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITALVAWPLTYWPHKALSQFILSANiAPGTGITGAVNHYYGKK 84
Cdd:PRK13629   17 WRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGS-NPSGNITETVEEHFGKT 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499  85 IGNLITGLYFLAFFVVVLIYAVAITNSLAEQVAHRTPMTPGLRALLSLGVVLVLNLIFLMGRQVTIKVMGFLVFPLIACF 164
Cdd:PRK13629   96 GGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASL 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 165 LFLSLYLIRDWHPEHLT----SQMQFSPQ--TLHQVWISIPVMVFAFSHTPIISTFAIDQQEKH-----GDLAMGKCKKI 233
Cdd:PRK13629  176 VLISLSLIPYWNSAVIDqvdlGSLSLTGHdgILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYekdfgRDFTERKCSQI 255

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 234 MKVAYTIICASVLFFVFSCLLAIPATYIETARDQGVTILSAL----SMVPGAPGWLAVT----GIIVAVVAMSKSFLGTY 305
Cdd:PRK13629  256 ISRASMLMVAVVMFFAFSCLFTLSPQNMAEAKAQNIPVLSYLanhfASMTGTKSTFAITleyaASIIALVAIFKSFFGHY 335

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1429757499 306 FGVIEGASEIVkSSLGLLGVRKSRAFNR--AMSILLVSAFTFAVCFINPNAISMIYAISGPLIAMILFIMPTLSTWLIPA 383
Cdd:PRK13629  336 LGTLEGLNGLI-LKFGYKGDKTKVSLGKlnTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPS 414

                         410       420
                  ....*....|....*....|.
gi 1429757499 384 LKPYRS-VGNAITLVVGLLCV 403
Cdd:PRK13629  415 LAKYRGrLDNVFVTVIGLLTI 435
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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