|
Name |
Accession |
Description |
Interval |
E-value |
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
7-525 |
6.45e-145 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 427.27 E-value: 6.45e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 7 QAFWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQKEAEE 86
Cdd:COG5841 4 QSFLKGALILTAAGLISKILGAIYRIPLQNIIGDEGFGLYQMAYPIYGLFLTLATAGIPVAISKLVAEYNALGDYKGARR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 87 IICVSFWFLLGIGFIGFFTLFFGAETIASA-MGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTI 165
Cdd:COG5841 84 IFRVSLLLLLILGLVFFLLLFFGAPFIARLlLGDPRAYYSLRALAPALLIVPVMSVLRGYFQGLQNMTPTAVSQVIEQIV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 166 RVSIIVFLSLFLIAHGfdLYTVGAGAMLGSIAGGLIGIIVLLLYMRHDFRAIFFKSLKRVGGK----RRIVKILFWQGIA 241
Cdd:COG5841 164 RVIFILLLAYLLLPYG--LEYAAAGATFGAVIGALAGLLVLLYYYRKRKKKLKRLLEKSKTKSkessKDILKELLRIAIP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 242 ICVSNLVLIFIQMADSVSFYTLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLAFIQE 320
Cdd:COG5841 242 ITLSSLVLPLFQLIDSFTVPRRLQAAGLSASEATSLYGILSgMAQPLVNLPTVLATALATSLVPAISEAFAKKDRKLVRR 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 321 KVKLAMKITLVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCL 400
Cdd:COG5841 322 RINQALRLTLLIGLPAAVGLAVLAEPINTLLFGNPEGGGILAILAPSAIFLSLQQVTTGILQGLGKQKIPVINLLIGLLV 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 401 KLVLNYMLMPHFGVKGAAIATLIALVVIALLNSVLLMQSVSGSLINKQKMFGIVISGISMGFVLIMFIRVLQMsglvIDG 480
Cdd:COG5841 402 KIILNYLLVPLFGIYGAALATVIGYLVAAILNLAALKKYTGFKLDLRRRLLKPLLASLIMGIVVLLLYRLLSL----FLP 477
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1586385907 481 NHRGIATFEALLGVAIGGLTYMFLILKLRVFTKEELGSVMKKEKK 525
Cdd:COG5841 478 ESRLGALLATLIAVLVGAIVYLLLLLKLGLITKEELRRLPKGGKK 522
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
14-436 |
1.18e-135 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 399.92 E-value: 1.18e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 14 IILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQKEAEEIICVSFW 93
Cdd:cd13124 1 LILTIAGLISKILGAIYRIPLQNIIGDEGMGLYQMAYPIYGIFLTLATAGIPVAISKLVAEYNALGDYKGARRIFRVSLI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 94 FLLGIGFIGFFTLFFGAETIASA-MGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVSIIVF 172
Cdd:cd13124 81 LLLILGLVFFLLLFFGAPFLAQLlLGDPRLAPVIRALAPAILIVPLLSVLRGYFQGLQNMTPTAVSQVIEQIVRVIVILV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 173 LSLFLIAHGFDLYTVGAGAMLGSIAGGLIGIIVLLLYM---RHDFRAIFFKSLKRVGGKRRIVKILFWQGIAICVSNLVL 249
Cdd:cd13124 161 LAYLLLPVGGGLYYAAAGATFGAVIGALAGLLVLLYYYrkkRRELKRLLRKSPRSKISTKEILKELLSYAIPITLSSLIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 250 IFIQMADSVSFYTLLIGAGEQAESAKVLKGVY-DRSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLAFIQEKVKLAMKI 328
Cdd:cd13124 241 PLLQLIDSFTVPRRLQAAGLSESEATALYGILtGRAQPLVQLPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 329 TLVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCLKLVLNYML 408
Cdd:cd13124 321 TLLIGLPAAVGLAVLAEPINTLLFGDSEGGLILQILAPSILFLSLQQVTAAILQGLGKVKIPVINLLIGLLVKIVLNYVL 400
|
410 420
....*....|....*....|....*...
gi 1586385907 409 MPHFGVKGAAIATLIALVVIALLNSVLL 436
Cdd:cd13124 401 IPIFGIYGAAIATVIGFLVAALLNLRAL 428
|
|
| spore_V_B |
TIGR02900 |
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial ... |
9-432 |
4.21e-40 |
|
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial endopore formation program in Bacillus subtilis and various other Firmcutes. It is nearly universal among endospore-formers. Paralogs with rather high sequence similarity to SpoVB exist, including YkvU in B. subtilis and a number of proteins in the genus Clostridium. [Cellular processes, Sporulation and germination]
Pssm-ID: 274343 [Multi-domain] Cd Length: 488 Bit Score: 151.68 E-value: 4.21e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 9 FWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQKEAEEII 88
Cdd:TIGR02900 1 FLKGTFILTIANLITRILGFIFRIVLSRILGAEGVGLYGMAMPIYFLFITLTTGGLPVAISKFVAEASAKNDRKNIKKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 89 CVSFWFLLGIGFIGFFTLFFGAETIASAM-GDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:TIGR02900 81 KVSLIFTLIWSLIVTAIVFLLSPFIASTLlKDERSLYSLLVICPAMPFIALSSVLKGYFQGISNMKPPAYIQVIEQIVRI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 168 SI-IVFLSLFLIAhgfDLYTVGAGAMLGSIAGGLIGIIVLL-LYMRHDFRAIFFKSLKRVGGKRRIVKILFWQGIAICVS 245
Cdd:TIGR02900 161 SVvALLISAFLPY---GLEYAVAGAYLSLVLGELVSLLYLYfFFKRKKSFSIRFPFFDYKSEGKALLFDLFSVSLPLTLS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 246 NLVLIFIQMADSVSFYTLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLAFIQEKVKL 324
Cdd:TIGR02900 238 RFIGSLLYFLETLLVPQRLVIAGVTYREATSLYGKLSgMAMPLLTFPAVITSSLSTALVPDISEAMAKKNYSSIEKRINQ 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 325 AMKITLVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCLKLVL 404
Cdd:TIGR02900 318 AIKISLLLGLITTVILLVIPDELGALFYGRPDAGNFIRVLAPSFPFLYFSAPLQSILQGLGKQKVALRNSLIGAIVKIIL 397
|
410 420 430
....*....|....*....|....*....|
gi 1586385907 405 NYML--MPHFGVKGAAIATLIALVVIALLN 432
Cdd:TIGR02900 398 LFVLtsIPSINIYGYAITFIITSVLVTILN 427
|
|
| Polysacc_synt |
pfam01943 |
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. ... |
9-307 |
3.45e-20 |
|
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis, which is involved in spore cortex biosynthesis.
Pssm-ID: 426523 [Multi-domain] Cd Length: 274 Bit Score: 90.44 E-value: 3.45e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 9 FWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKqkeaeeiI 88
Cdd:pfam01943 1 LLKNVIVLLLSQLITYLLAFVTLPYLARILGPEGFGLYAFALAFVGLLTIFTDFGFNAALVREIAKYREKYE-------L 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 89 CVSFWFLLGIGFIGFFTLFFGAETIASAMGDVHLYKLLRVISFSSILMPF-LSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:pfam01943 74 VSLYWLNALLVKLVLVLLFLLLPLIAAFLGLPELAVLYRILALMFLLLPGvVQFRRGLFQGLERMKYALISQIVESLSRV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 168 SiivfLSLFLIAHGFDLYTVGAGAMLGSIAGGLIGIIVLllymRHDFRAIFFKSlkrvggKRRIVKILFWQGIAICVSNL 247
Cdd:pfam01943 154 I----LVFIAVFLPGDIVAALLYQVLAALVGGIIALAVL----RKIFRPRFVFP------SLKLVRKLLSFGAPLFISSL 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1586385907 248 VLIFIQMADSVsFYTLLIGAGEqaesakvlKGVYDRSIPLMQLGT-VVTTSFSLSLIPIIT 307
Cdd:pfam01943 220 AISLYTYIDSI-LLGLLLGAGA--------VGIYNAAYQLLVAIQgLLNPIVTAVLFPVFS 271
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
7-525 |
6.45e-145 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 427.27 E-value: 6.45e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 7 QAFWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQKEAEE 86
Cdd:COG5841 4 QSFLKGALILTAAGLISKILGAIYRIPLQNIIGDEGFGLYQMAYPIYGLFLTLATAGIPVAISKLVAEYNALGDYKGARR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 87 IICVSFWFLLGIGFIGFFTLFFGAETIASA-MGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTI 165
Cdd:COG5841 84 IFRVSLLLLLILGLVFFLLLFFGAPFIARLlLGDPRAYYSLRALAPALLIVPVMSVLRGYFQGLQNMTPTAVSQVIEQIV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 166 RVSIIVFLSLFLIAHGfdLYTVGAGAMLGSIAGGLIGIIVLLLYMRHDFRAIFFKSLKRVGGK----RRIVKILFWQGIA 241
Cdd:COG5841 164 RVIFILLLAYLLLPYG--LEYAAAGATFGAVIGALAGLLVLLYYYRKRKKKLKRLLEKSKTKSkessKDILKELLRIAIP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 242 ICVSNLVLIFIQMADSVSFYTLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLAFIQE 320
Cdd:COG5841 242 ITLSSLVLPLFQLIDSFTVPRRLQAAGLSASEATSLYGILSgMAQPLVNLPTVLATALATSLVPAISEAFAKKDRKLVRR 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 321 KVKLAMKITLVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCL 400
Cdd:COG5841 322 RINQALRLTLLIGLPAAVGLAVLAEPINTLLFGNPEGGGILAILAPSAIFLSLQQVTTGILQGLGKQKIPVINLLIGLLV 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 401 KLVLNYMLMPHFGVKGAAIATLIALVVIALLNSVLLMQSVSGSLINKQKMFGIVISGISMGFVLIMFIRVLQMsglvIDG 480
Cdd:COG5841 402 KIILNYLLVPLFGIYGAALATVIGYLVAAILNLAALKKYTGFKLDLRRRLLKPLLASLIMGIVVLLLYRLLSL----FLP 477
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 1586385907 481 NHRGIATFEALLGVAIGGLTYMFLILKLRVFTKEELGSVMKKEKK 525
Cdd:COG5841 478 ESRLGALLATLIAVLVGAIVYLLLLLKLGLITKEELRRLPKGGKK 522
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
14-436 |
1.18e-135 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 399.92 E-value: 1.18e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 14 IILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQKEAEEIICVSFW 93
Cdd:cd13124 1 LILTIAGLISKILGAIYRIPLQNIIGDEGMGLYQMAYPIYGIFLTLATAGIPVAISKLVAEYNALGDYKGARRIFRVSLI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 94 FLLGIGFIGFFTLFFGAETIASA-MGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVSIIVF 172
Cdd:cd13124 81 LLLILGLVFFLLLFFGAPFLAQLlLGDPRLAPVIRALAPAILIVPLLSVLRGYFQGLQNMTPTAVSQVIEQIVRVIVILV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 173 LSLFLIAHGFDLYTVGAGAMLGSIAGGLIGIIVLLLYM---RHDFRAIFFKSLKRVGGKRRIVKILFWQGIAICVSNLVL 249
Cdd:cd13124 161 LAYLLLPVGGGLYYAAAGATFGAVIGALAGLLVLLYYYrkkRRELKRLLRKSPRSKISTKEILKELLSYAIPITLSSLIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 250 IFIQMADSVSFYTLLIGAGEQAESAKVLKGVY-DRSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLAFIQEKVKLAMKI 328
Cdd:cd13124 241 PLLQLIDSFTVPRRLQAAGLSESEATALYGILtGRAQPLVQLPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 329 TLVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCLKLVLNYML 408
Cdd:cd13124 321 TLLIGLPAAVGLAVLAEPINTLLFGDSEGGLILQILAPSILFLSLQQVTAAILQGLGKVKIPVINLLIGLLVKIVLNYVL 400
|
410 420
....*....|....*....|....*...
gi 1586385907 409 MPHFGVKGAAIATLIALVVIALLNSVLL 436
Cdd:cd13124 401 IPIFGIYGAAIATVIGFLVAALLNLRAL 428
|
|
| spore_V_B |
TIGR02900 |
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial ... |
9-432 |
4.21e-40 |
|
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial endopore formation program in Bacillus subtilis and various other Firmcutes. It is nearly universal among endospore-formers. Paralogs with rather high sequence similarity to SpoVB exist, including YkvU in B. subtilis and a number of proteins in the genus Clostridium. [Cellular processes, Sporulation and germination]
Pssm-ID: 274343 [Multi-domain] Cd Length: 488 Bit Score: 151.68 E-value: 4.21e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 9 FWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQKEAEEII 88
Cdd:TIGR02900 1 FLKGTFILTIANLITRILGFIFRIVLSRILGAEGVGLYGMAMPIYFLFITLTTGGLPVAISKFVAEASAKNDRKNIKKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 89 CVSFWFLLGIGFIGFFTLFFGAETIASAM-GDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:TIGR02900 81 KVSLIFTLIWSLIVTAIVFLLSPFIASTLlKDERSLYSLLVICPAMPFIALSSVLKGYFQGISNMKPPAYIQVIEQIVRI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 168 SI-IVFLSLFLIAhgfDLYTVGAGAMLGSIAGGLIGIIVLL-LYMRHDFRAIFFKSLKRVGGKRRIVKILFWQGIAICVS 245
Cdd:TIGR02900 161 SVvALLISAFLPY---GLEYAVAGAYLSLVLGELVSLLYLYfFFKRKKSFSIRFPFFDYKSEGKALLFDLFSVSLPLTLS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 246 NLVLIFIQMADSVSFYTLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLAFIQEKVKL 324
Cdd:TIGR02900 238 RFIGSLLYFLETLLVPQRLVIAGVTYREATSLYGKLSgMAMPLLTFPAVITSSLSTALVPDISEAMAKKNYSSIEKRINQ 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 325 AMKITLVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCLKLVL 404
Cdd:TIGR02900 318 AIKISLLLGLITTVILLVIPDELGALFYGRPDAGNFIRVLAPSFPFLYFSAPLQSILQGLGKQKVALRNSLIGAIVKIIL 397
|
410 420 430
....*....|....*....|....*....|
gi 1586385907 405 NYML--MPHFGVKGAAIATLIALVVIALLN 432
Cdd:TIGR02900 398 LFVLtsIPSINIYGYAITFIITSVLVTILN 427
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
11-436 |
1.92e-28 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 116.87 E-value: 1.92e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 11 RGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLErgkqKEAEEIICV 90
Cdd:cd13128 3 KNSGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFSIFADLGLPTALVREIARYRK----EKIREIIST 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 91 SFWFLLGIGFIGFFTLFFGAETIASamGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVSII 170
Cdd:cd13128 79 SLVLKLILGILALLLLFLFAFLIAF--YDPELVLLLYILALSLPFSALNSLFRGIFQGFEKMKYIVIARIIESVLSLILA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 171 VFLSLFliahGFDLYtvgaGAMLGSIAGGLIGIIVLLLYMRHDFRAIFFKSLKRvggkrRIVKILFWQGIAICVSNLVLI 250
Cdd:cd13128 157 LILVLL----GGGLI----GFALAYLIASVLSAILLLYIYRKKILLPKFFSFDL-----KLAKELLRFSIPLALSGIFSL 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 251 FIQMADSVsfytlLIGAGEQAESAkvlkGVYDRSIPLMQLGTVVTTSFSLSLIPIITAAKERgDLAFIQEKVKLAMKITL 330
Cdd:cd13128 224 IYTRIDTI-----MLGYFLGDAAV----GIYNAAYRIAELLLFIPSAISTALFPRISELYKN-DKDELKKLLKKSFKYLF 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 331 VIGFAAAIGLTCIIQPTNIMLF--ENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCLKLVLNYML 408
Cdd:cd13128 294 LISLPIAIGLFLFAEPIITLLFgeEYLPAALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGALLNVILNLLL 373
|
410 420
....*....|....*....|....*...
gi 1586385907 409 MPHFGVKGAAIATLIALVVIALLNSVLL 436
Cdd:cd13128 374 IPKYGIIGAAIATLISEFIIFILLLYLL 401
|
|
| Polysacc_synt |
pfam01943 |
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. ... |
9-307 |
3.45e-20 |
|
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis, which is involved in spore cortex biosynthesis.
Pssm-ID: 426523 [Multi-domain] Cd Length: 274 Bit Score: 90.44 E-value: 3.45e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 9 FWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKqkeaeeiI 88
Cdd:pfam01943 1 LLKNVIVLLLSQLITYLLAFVTLPYLARILGPEGFGLYAFALAFVGLLTIFTDFGFNAALVREIAKYREKYE-------L 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 89 CVSFWFLLGIGFIGFFTLFFGAETIASAMGDVHLYKLLRVISFSSILMPF-LSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:pfam01943 74 VSLYWLNALLVKLVLVLLFLLLPLIAAFLGLPELAVLYRILALMFLLLPGvVQFRRGLFQGLERMKYALISQIVESLSRV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 168 SiivfLSLFLIAHGFDLYTVGAGAMLGSIAGGLIGIIVLllymRHDFRAIFFKSlkrvggKRRIVKILFWQGIAICVSNL 247
Cdd:pfam01943 154 I----LVFIAVFLPGDIVAALLYQVLAALVGGIIALAVL----RKIFRPRFVFP------SLKLVRKLLSFGAPLFISSL 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1586385907 248 VLIFIQMADSVsFYTLLIGAGEqaesakvlKGVYDRSIPLMQLGT-VVTTSFSLSLIPIIT 307
Cdd:pfam01943 220 AISLYTYIDSI-LLGLLLGAGA--------VGIYNAAYQLLVAIQgLLNPIVTAVLFPVFS 271
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
9-431 |
2.56e-19 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 89.62 E-value: 2.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 9 FWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERgkqkEAEEII 88
Cdd:COG2244 4 LLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLFALALSIVALLSVLADLGLSTALVRFIAEYREE----ELRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 89 CVSFWFLLGIGFIGFFTLFFGAETIASAMGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRvs 168
Cdd:COG2244 80 STALLLRLLLSLLLALLLLLLAPFIAALLGEPELALLLLLLALALLLSALSAVLLALLRGLERFKLLALINILSSLLS-- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 169 iivflslfliahgfdlytvgagamlgsiagglIGIIVLLLYMRHDFRAIFFKslkrvggkrrivkilfwQGIAICVSNLV 248
Cdd:COG2244 158 --------------------------------LLLALLLALLGLGLWGLVLK-----------------YSLPLLLSGLL 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 249 LIFIQMADsvsfyTLLIGAGEQAESAkvlkGVYDRSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLAFIQEKVKLAMKI 328
Cdd:COG2244 189 GLLLTNLD-----RLLLGALLGPAAV----GIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRL 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 329 TLVIGFAAAIGLTCIIQPTNIMLF--ENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVVFGGCLKLVLNY 406
Cdd:COG2244 260 LLLLGLPLALGLALLAPPLLSLLFgpEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNL 339
|
410 420
....*....|....*....|....*
gi 1586385907 407 MLMPHFGVKGAAIATLIALVVIALL 431
Cdd:COG2244 340 LLIPRYGLVGAAIATLLSYLVLLLL 364
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
376-510 |
3.76e-13 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 66.83 E-value: 3.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 376 TTASILQGLGQTLKPAIFVVFGGCLKLVLNYMLMPHFGVKGAAIATLIALVVIALLNSVLLMQSVSGSLINKqKMFGIVI 455
Cdd:pfam14667 17 VLTSILQGLGRTKLALIALLIGALVKLILNLLLIPLFGIVGAAIATVISLLVVALLNLYYLRRYLGLRLLLR-RLLKPLL 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1586385907 456 SGISMGFVLIMFIRVLQMSGLVidgnhrgiaTFEALLGVAIGGLTYMFLILKLRV 510
Cdd:pfam14667 96 AALVMGIVVYLLLLLLGLLLGL---------ALALLLAVLVGALVYLLLLLLLKL 141
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
57-431 |
3.20e-12 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 68.50 E-value: 3.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 57 LILATYGFPIIISKMVAERLERGKQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAMGDVHLY-----KLLRVISF 131
Cdd:cd12082 43 LIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVLAILLGLLLAALLLFFSPLILSLLGAEEEVielaaTYLTILIL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 132 SSILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVSIIVFLSLFLIAHGFDLytvgAGAMLGSIAGGLIGIIVLLLYMR 211
Cdd:cd12082 123 GLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNILLDPLLIFGLGPPELGI----AGAALATVISYVIGALLLLIYLR 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 212 HDFRAIFFKSLKRVGGK---RRIVKILFWQGIAICVSNLVLIFIqmadsVSFYTLLIGAGEQAesakvlkgVYDRSIPLM 288
Cdd:cd12082 199 KGKKILKFKLSLLKPDLellRRLLRIGLPSAIQNSLLSLGLLII-----VAIVAAFGGAAALA--------AYTVAFRIA 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 289 QLGTVVTTSFSLSLIPIITAAKERGDLAFIQEKVKLAMKITLVIGfaAAIGLTCIIQPTNIM-LFENSD-----GSDVLS 362
Cdd:cd12082 266 SLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIG--AVLGLLILLFPEPILsLFTNDPeflelAVSYLR 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1586385907 363 ILSLSILFSSLSITTASILQGLGQTLKPAIFV-VFGGCLKLVLNYMLMP-HFGVKGAAIATLIALVVIALL 431
Cdd:cd12082 344 ILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSlLSYWVVRLPLAYVLAYlGLGLYGIWLALVISLILAALV 414
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
71-431 |
4.61e-12 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 67.86 E-value: 4.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 71 MVAERLERGKQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAMG-DVHLYKL----LRVISFSSILMPFLSVARGY 145
Cdd:COG0534 70 LVAQALGAGDREEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGaDPEVLALardyLRIILLGLPFLLLFNVLNGI 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 146 FQGFNNMMPTAVSQVIeqtirVSII-VFLSLFLIaHGFDLYTVGAGamLGSIAGGLIGIIVLLLYMRHDFRAIFFkSLKR 224
Cdd:COG0534 150 LRGLGDTKTPMIIMLI-----GNVLnIVLDPLLI-FGGGLGVAGAA--LATVISQAVSALLLLYYLFRKRSLLRL-RLRD 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 225 VGGKRRIVKILFWQGIAICVSNLVLIFIQMAdsvsFYTLLIGAGEQAESAKVLkgvydrSIPLMQLGTVVTTSFSLSLIP 304
Cdd:COG0534 221 LRPDRKILKRILRIGLPAGLQQLAESLGFLV----LNALVARLGTAAVAAYGI------ALRIESLAFMPALGLGQAAQP 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 305 IITAAKERGDLAFIQEKVKLAMKITLVIGFAAAIgLTCIIQPTNIMLFENSD-----GSDVLSILSLSILFSSLSITTAS 379
Cdd:COG0534 291 LVGQNLGAGDYDRARRAARLALLLALGIGLLLAL-LLFLFPEPIIGLFTDDPevialAATYLRIAALFQPFDGLQFVLSG 369
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1586385907 380 ILQGLGQTLKPAIFVVFGGCLKLVLNYMLMPH--FGVKGAAIATLIALVVIALL 431
Cdd:COG0534 370 ALRGAGDTRFPMIISLLRLWLVRLPLAYLLAFlgLGLTGVWLALPIGEVLRALL 423
|
|
| MATE_tuaB_like |
cd13127 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This ... |
80-445 |
1.74e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240532 [Multi-domain] Cd Length: 406 Bit Score: 59.81 E-value: 1.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 80 KQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAMGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAVSQ 159
Cdd:cd13127 63 RKDLTEEDLSTVFWLNLLLGLLLYLLLFLLAPLIAAFYNEPELIPLLRVLSLSFLLSGLGSVPRALLQRELRFKKLAIIE 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 160 VIEQTIRVSIIVFLSLFliahgfdlytvGAGAM---LGSIAGGLIGIIVLLLYMRHDFRAIFfkslkrvggKRRIVKILF 236
Cdd:cd13127 143 LISTLVSGVVAIVLALL-----------GFGVWalvAQQLVGALVSTVLLWILSRWRPRLSF---------SLASLKELL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 237 WQGIAICVSNLVLIFiqmadSVSFYTLLIGAgeqAESAKVLkGVYDRSIPLMQLG-TVVTTSFSLSLIPIItaAKERGDL 315
Cdd:cd13127 203 SFGSKLLGSNLLNYF-----SRNLDNLIIGK---FLGAAAL-GYYSRAYRLALLPvQNITGPITRVLFPAL--SRLQDDP 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 316 AFIQEKVKLAMKITLVIGFAAAIGLTCIIQP-TNIMLFEN-SDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIF 393
Cdd:cd13127 272 ERLRRAYLKALRLLALITFPLMVGLALLAEPlVLLLLGEKwLPAVPILQILALAGLFQPLSSLNGSLLLALGRTDLLLKL 351
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1586385907 394 VVFGGCLKLVLnYMLMPHFGVKGAAIATLIALVVIALLNSVLLMQSVSGSLI 445
Cdd:cd13127 352 GLIKAVLTVLA-LLIGIPYGIIGVAIAYVIASLLSFPLNLYLAGRLIGISLL 402
|
|
| MurJ |
COG0728 |
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
71-510 |
3.64e-09 |
|
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 59.01 E-value: 3.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 71 MVAERLERGKQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAM-GDVHLYKLLRVISFSSILMPFL------SVAR 143
Cdd:COG0728 64 VLAEALEKEGEEEARRFASRVLTLLLLVLLVLTLLGILFAPLLVKLLaPGFDPEKFALAVALTRIMFPYIlfiglsALLG 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 144 GYFQGFNNMMPTAVSQVIeqtIRVSIIVFLSLFLIAHGFDLYTVGAGAMLGSIAGGLIGIIVLLlymRHDFRAIFFKSLK 223
Cdd:COG0728 144 GVLNARGRFAAPALAPVL---LNLVIIAGLLLLAPLFGPGIYALAWGVLLGGVLQLLIQLPALR---RLGLRLRPRFDLR 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 224 RVGGkRRIVKILFWQGIAICVSNLVLIFIQMadsvsfytLLIGAGEQAESAkvlkgvYDRSIPLMQLGT-VVTTSFSLSL 302
Cdd:COG0728 218 DPGV-RRVLKLMLPALLGVSVSQINLLVDTI--------LASFLPEGSVSA------LYYADRLYQLPLgLFGVAIGTAL 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 303 IPIITAAKERGDLAFIQEKVKLAMKITLVIGFAAAIGLTCIIQPTNIMLFE--NSDGSDVLSilslsilfsslsitTASI 380
Cdd:COG0728 283 LPRLSRAAAAGDLEEFRRTLSRGLRLVLLLTLPAAVGLIVLAEPIVRLLFErgAFTAEDTAL--------------TALA 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 381 LQG--------------------LGQTLKPAIFVVFGGCLKLVLNYMLMPHFGVKGAAIATLIALVVIALLNSVLLMQSV 440
Cdd:COG0728 349 LAAyalglpafalvkvlarafyaRQDTRTPVRIAVIAVVVNIVLNLLLVPPLGHAGLALATSLSALVNALLLLVLLRRRL 428
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1586385907 441 SGSLINKQKMFG--IVISGISMGFVLIMFIRVLQMsglvIDGNHRGIATFEALLGVAIGGLTYMFLILKLRV 510
Cdd:COG0728 429 GGLPLRGILRTLlkLLLASLVMGAVLWLLLRLLGD----WLGGGLLGRLLALALLILVGAAVYFALLLLLGV 496
|
|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
72-437 |
4.77e-07 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 52.13 E-value: 4.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 72 VAERLERGKQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAMG-DVHLYKL----LRVISFSSILMPFLSVARGYF 146
Cdd:cd13143 68 ISRRLGAGDREKANRIFSTALLLSLILGLLLTILGLLFLDPLLRLLGaSGELLPYavdyLRIILLGAPFTILSSVLNNLL 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 147 QGFNN----MMPTAVSQVIEqtirvsiIVFLSLFLIAHGFDLytvgAGAMLGSIAGGLIGIIVLLLYMRHdFRAIFFKSL 222
Cdd:cd13143 148 RAEGKpklaMLGMLIGAVLN-------IILDPLFIFVLGLGI----AGAALATVIAQLISLLLLLLYFFR-GKSLLKLSL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 223 KRVGGKRRIVKILFWQGIAICVSNLVLIFIQMadsVSFYTLLIGAGEQAESAkvlkgvYDRSIPLMQLGTVVTTSFSLSL 302
Cdd:cd13143 216 LRFKLSLKIIKEILALGFPSFLMQLSSSVVTI---VLNLTLLGYGGDIGVAA------FGIVTRILTFLFLPLIGLSQGL 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 303 IPIITAAKERGDLAFIQEKVKLAMKITLVIGFAAAIglTCIIQPTNIMLFENSD------GSDVLSILSLSILFSSLSIT 376
Cdd:cd13143 287 QPIIGYNYGAGNYDRVKQALKLALIVALIYGLVLFL--ILLLFPEQIVSLFTDDpelialAARILRIFLLAFPLAGINIV 364
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1586385907 377 TASILQGLGQTLKPAIFVVFGGCLKLVLNYMLMPH-FGVKGAAIATLIALVVIALLNSVLLM 437
Cdd:cd13143 365 LSGYFQAIGKAKRAALLSLLRQGLFLIPLLLILPRlFGLDGIWLAFPLAEILTLLLALILLK 426
|
|
| Polysacc_synt_3 |
pfam13440 |
Polysaccharide biosynthesis protein; |
80-340 |
1.15e-06 |
|
Polysaccharide biosynthesis protein;
Pssm-ID: 404342 [Multi-domain] Cd Length: 293 Bit Score: 50.28 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 80 KQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAMGDVHLYKLLRVISFSSILMPFLSVARGYFQgfnnmmpTAVSQ 159
Cdd:pfam13440 39 KKDITETDYSTVFTFNLIFGALIYLILFALAPLIASFYNQPELVPVLRVLALVLILNGLSSVQTALLR-------RDLRF 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 160 VIEQTIRVSIIVFLSLFLIAHGFDLYTVGAGAmLGSIAGGLigIIVLLLYMRHDFRAiffkslkRVGGKRRIVKILFWQG 239
Cdd:pfam13440 112 KKLFKITLTSSVIGGIVGIVLAYLGFGVWALV-IGTLAQQL--LSLVLLWLASDWRP-------RLTFSLKVIKELFSFG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 240 IAICVSNLVLIFIQMADSvsfytLLIGageQAESAKVLkGVYDRSIPLMQL-GTVVTTSFSLSLIPIITAAKErgDLAFI 318
Cdd:pfam13440 182 SWLLLSNLLNYLARNLDN-----LIIG---KVLGTAAL-GLYSVAYRLALLpTANITSVITKVLFPALSRIQD--DKAKL 250
|
250 260
....*....|....*....|..
gi 1586385907 319 QEKVKLAMKITLVIGFAAAIGL 340
Cdd:pfam13440 251 RELYLRVLRLIAFIVFPIMAGL 272
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
54-212 |
7.32e-06 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 48.61 E-value: 7.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 54 GFCLILATyGFPIIISKMVAERLERGKQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAM-GDVHLYKL----LRV 128
Cdd:cd13138 271 SFAFLPPS-AIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLIIILLVFFFAPQLLGLFtSDPEVIEIgaeyLRI 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 129 ISFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEQ-TIRVSIIVFLSLFLiahGFDLYTVGAGAMLGSIAGGLIGIIVLL 207
Cdd:cd13138 350 YSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLwLVRIPLAYLLSRLT---GLGLFGIWLAMPISNILSAIICIIYYR 426
|
....*
gi 1586385907 208 LYMRH 212
Cdd:cd13138 427 KGRWK 431
|
|
| MATE_epsE_like |
cd13129 |
Multidrug and toxic compound extrusion family and similar proteins; This model represents a ... |
9-216 |
1.49e-05 |
|
Multidrug and toxic compound extrusion family and similar proteins; This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins, including Ralstonia solanaceraum GMI1000 epsE, which may be involved in exporting exopolysaccharide EPS I, a virulence factor. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240534 [Multi-domain] Cd Length: 411 Bit Score: 47.48 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 9 FWRGAIILTIASFITKVLSAFYRIPYQNIAGDVGFYIYQQIYPFYGFCLILATYGFPIIISKMVAErLERGKQKEAEEII 88
Cdd:cd13129 2 FASGSFWSLGGLVASRGAVFLTNIMVARSLGKHVFGEFGVIQVTIGLLGTFAGFGLGLAATKVIAE-TKDVDPERAGRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 89 CVSFWFLLGIGFIGFFTLFFGAETIA-SAMGDVHLYKLLRVISFSSILMPFLSVARGYFQGFNNMMPTAvsqvieqtiRV 167
Cdd:cd13129 81 GLSILLAVVTGALAATVLFLSATWIAiATLNAPHLAELLRIAAIILILTAFTGAQTGFLSGFEAFRAIA---------RV 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1586385907 168 SIIVFLSLFLIAHGFDLYTVGAGAMLGSIAGGLIGIIVLLLYMRHDFRA 216
Cdd:cd13129 152 NIWAGLLLLPLMWIGVYIRGLVGAVVILLASAAGNVASNSLILRRECQN 200
|
|
| MATE_MurJ_like |
cd13123 |
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
73-436 |
1.97e-05 |
|
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240528 [Multi-domain] Cd Length: 420 Bit Score: 47.06 E-value: 1.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 73 AERLERGKQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAM-GDVHLYKLLRVISFSSILMPFL------SVARGY 145
Cdd:cd13123 59 SEYLEKEGEEEARRFASRVLTLLLLVLLLLTLLGILFAPLLVKLLaPGFSGDKFELAVALTRIMFPYLlfislsALLGGI 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 146 FQGFNNMMPTAVSQVIeqtIRVSIIVFLSLFLIAHGFDLYTVGAGAMLGSIAGGLIGIIVLLlymRHDFRaIFFKSLKRV 225
Cdd:cd13123 139 LNAHGRFFAPALAPVL---LNLVIIAGLLLLAPLFDLGIYALAWGVLLGGVLQLLVQLPALR---RLGFR-FRPRLDFRD 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 226 GGKRRIVKILFWQGIAICVSNLVLIFIQMADSvsfytlliGAGEQAESAkvlkgvYDRSIPLMQLGT-VVTTSFSLSLIP 304
Cdd:cd13123 212 PGVRRVLKLMLPALLGVSVSQINLLVDTILAS--------FLPEGSISA------LYYADRLYQLPLgIFGVAIATALLP 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 305 IITAAKERGDLAFIQEKVKLAMKITLVIGFAAAIGLTCIIQPTNIMLFE--NSDGSDVLSilslsilfsslsitTASILQ 382
Cdd:cd13123 278 RLSRLAAAGDLDEFRRTLSRGLRLVLFLLLPAAVGLIVLAEPIVRLLFErgAFTAEDTLM--------------TASALA 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1586385907 383 G--------------------LGQTLKPAIFVVFGGCLKLVLNYMLMPHFGVKGAAIATLIALVVIALLNSVLL 436
Cdd:cd13123 344 AyalglpafalvkllsrafyaLKDTKTPVKIAVIAVAVNILLNLLLIKPLGHVGLALATSLSAWVNALLLLVLL 417
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
378-431 |
2.22e-05 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 47.07 E-value: 2.22e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1586385907 378 ASILQGLGQTLKPAIFVVFGGCLKLVLNYMLM--PHFGVKGAAIATLIALVVIALL 431
Cdd:cd13138 143 SAILRGLGDSKTPLYFVIIACVLNIILDLLFIavFHMGVAGAALATVIAQAISVLL 198
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
55-342 |
7.06e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 45.21 E-value: 7.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 55 FCLILATYGFPIIISKMVAERLERGKQKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAMG-DVHLYKL----LRVI 129
Cdd:cd13133 51 FAILMLFFGLSSGVQVFVAQYNGAGRYSRIGRVLWQGLYFSLLLAPLLALLSALAAPLLFLLLGhSPEVQALeveyFRIR 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 130 SFSSILMPFLSVARGYFQGFNNMMPTAVSQVIEqtirVSIIVFLSLFLIAHGFDLYTVG-AGAMLGSIAGGLIGIIVLLL 208
Cdd:cd13133 131 ILGAPFSLLGAALRAFFSGIGRTRVVMVANLVM----VVVNIVLDYALIFGKLGFPAMGiAGAAIATVIAEAVSLLFFLL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 209 YM--RHDFRAIFFKSLKRVGGK--RRIVKILFWQGIAICVSNL-VLIFIQMADSV------------SFYTLL------- 264
Cdd:cd13133 207 LLfrRKNRRRFGLRRAWRFDREllRRILRLGLPSGLQFFLDVGaFTVFFLLIGRLgttelaatnivfSINSLAflpmigl 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 265 -----------IGAGEQAESAKVLkgvydRSIPLMQLGTVVTTSFSLSLIP--IITAAKERGDLAFIQEKVKLAMKITLV 331
Cdd:cd13133 287 giavsslvgqaLGAGRPDLAMRVT-----RRGLKLALAYMLLLGILFLLFPelLLSIFTPGADFALIAELAVPLLRFVAA 361
|
330
....*....|.
gi 1586385907 332 IGFAAAIGLTC 342
Cdd:cd13133 362 YILFDALALVF 372
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
378-437 |
2.68e-04 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 43.59 E-value: 2.68e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1586385907 378 ASILQGLGQTLKPAIFVVFGGCLKLVLNYMLM--PHFGVKGAAIATLIALVVIALLNSVLLM 437
Cdd:COG0534 147 NGILRGLGDTKTPMIIMLIGNVLNIVLDPLLIfgGGLGVAGAALATVISQAVSALLLLYYLF 208
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
376-437 |
4.22e-04 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 42.88 E-value: 4.22e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1586385907 376 TTASILQGLGQTLKPAIFVVFGGCLKLVLNYMLM------PHFGVKGAAIATLIALVVIALLNSVLLM 437
Cdd:cd13137 138 VGNAALRGAGDTKTPMYIMIIVNVLNIVLDYVLIfglwgfPGLGVAGAALATVISRVVGALLLLFLLL 205
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
56-225 |
3.69e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 39.97 E-value: 3.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 56 CLILATYGFPIIISKMVAERLErgkqKEAEEIICVSFWFLLGIGFIGFFTLFFGAETIASAMG---DVHLYKL--LRVIS 130
Cdd:cd13135 52 FLGSISIGFTILGSQSVGAKDI----KRINDYAISSIVYNSIIGVILFLLWLFGARIIFVLFGvdgQILGYSInyVRIFS 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 131 FSSILMPFLSVARGYFQGFNNMMPTavsqVIEQTIRVSIIVFLSLFLIAHGFDLYTVG-AGAMLGSIAGGLIGIIVLLLY 209
Cdd:cd13135 128 IYLLLLGILFTFSSILQGIGETKPI----MYGGIIKNLLNVILDYVLIFGNFGFPRLGiIGAAIATTIANVLNLIILVYL 203
|
170
....*....|....*.
gi 1586385907 210 MRHDFRAIFFKSLKRV 225
Cdd:cd13135 204 CRKIKKLTFKLSNTKV 219
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
380-471 |
7.50e-03 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 38.70 E-value: 7.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1586385907 380 ILQGLGQTLKPAIFVVFGGCLKLVLNYMLMPHF--GVKGAAIATLIALVVIALLNSVLLMQSVSGSLINK-QKMFGIVIS 456
Cdd:cd13136 145 WFRGLQDTRTPLILQIVGNVVNIVLDPLFVFGLgwGVAGAALATVIAQYLGALLGLWLLRRRVRLLGKSLsRRLPSKAAL 224
|
90
....*....|....*
gi 1586385907 457 GISMGFVLIMFIRVL 471
Cdd:cd13136 225 KRLFKLNRDIFIRTL 239
|
|
| |
