NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1590143752|gb|TDA20557|]
View 

winged helix family transcriptional regulator [Extibacter muris]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 10452771)

helix-turn-helix (HTH) domain-containing protein may bind DNA and function as a transcriptional regulator

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Trans_reg_C pfam00486
Transcriptional regulatory protein, C terminal;
53-129 4.62e-37

Transcriptional regulatory protein, C terminal;


:

Pssm-ID: 425712 [Multi-domain]  Cd Length: 77  Bit Score: 121.08  E-value: 4.62e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1590143752  53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDNPQYILTVWGVGYKF 129
Cdd:pfam00486   1 GEEVELTPKEFKLLELLAENPGRVVSREQLLEEVWGEDYDVDDNTVDVHISRLRKKLEDDPRDPRLIKTVRGVGYRL 77
 
Name Accession Description Interval E-value
Trans_reg_C pfam00486
Transcriptional regulatory protein, C terminal;
53-129 4.62e-37

Transcriptional regulatory protein, C terminal;


Pssm-ID: 425712 [Multi-domain]  Cd Length: 77  Bit Score: 121.08  E-value: 4.62e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1590143752  53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDNPQYILTVWGVGYKF 129
Cdd:pfam00486   1 GEEVELTPKEFKLLELLAENPGRVVSREQLLEEVWGEDYDVDDNTVDVHISRLRKKLEDDPRDPRLIKTVRGVGYRL 77
trans_reg_C cd00383
DNA-binding effector domain of two-component system response regulators; Bacteria and some ...
 39-129 7.22e-37

DNA-binding effector domain of two-component system response regulators; Bacteria and some eukaryotes use two-component signal transduction systems to detect and respond to changes in the environment. The systems consists of a sensor histidine kinase and a response regulator. The former autophosphorylates a histidine residue on detecting an external stimulus. The phosphate is then transferred to an invariant aspartate residue in a highly conserved receiver domain of the response regulator. Phosphorylation activates a variable effector domain of the response regulator, which triggers the cellular response. This C-terminal effector domain belongs to the winged helix-turn-helix family of transcriptional regulators and contains DNA and RNA polymerase binding sites. Several dimers or monomers bind head to tail to small tandem repeats upstream of the genes. The RNA polymerase binding sites interact with the alpha or sigma subunit of RNA polymerase.


Pssm-ID: 294013 [Multi-domain]  Cd Length: 89  Bit Score: 121.05  E-value: 7.22e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  39 FDIDPLTRTFTNEeGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPdNPQY 118
Cdd:cd00383     1 LRLDPARREVTVD-GEEVELTPKEFELLELLARNPGRVVSREELLEAVWGYDYEVDDRTVDVHISRLRKKLEDDP-EPRL 78

                          90
                  ....*....|.
gi 1590143752 119 ILTVWGVGYKF 129
Cdd:cd00383    79 IKTVRGVGYRL 89
Trans_reg_C smart00862
Transcriptional regulatory protein, C terminal; This domain is almost always found associated ...
 53-129 3.70e-34

Transcriptional regulatory protein, C terminal; This domain is almost always found associated with the response regulator receiver domain. It may play a role in DNA binding.


Pssm-ID: 214866 [Multi-domain]  Cd Length: 76  Bit Score: 113.80  E-value: 3.70e-34
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1590143752   53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDnPQYILTVWGVGYKF 129
Cdd:smart00862   1 GEPIKLTPKEFRLLELLLRNPGRVVSREELLEAVWGDDEDVDDNTLDVHISRLRKKLEDDGD-PRLIETVRGVGYRL 76
CadC1 COG3710
DNA-binding winged helix-turn-helix (wHTH) domain [Transcription];
38-132 4.98e-25

DNA-binding winged helix-turn-helix (wHTH) domain [Transcription];


Pssm-ID: 442924 [Multi-domain]  Cd Length: 106  Bit Score: 91.50  E-value: 4.98e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  38 GFDIDPLTRTFTNEeGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGfHNAPEGNNLTSFIRKLRKKIEPSPDNPQ 117
Cdd:COG3710     7 DFRLDPARRELLRD-GEPVRLSPRAFDLLLLLLEHPGRVVSRDELLAAVWP-GRVVSDNSLTQAISRLRKALGDDGLEPR 84

                          90
                  ....*....|....*
gi 1590143752 118 YILTVWGVGYKFNEE 132
Cdd:COG3710    85 LIRTVPRRGYRLVAP 99
orf27 CHL00148
Ycf27; Reviewed
 56-129 3.31e-16

Ycf27; Reviewed


Pssm-ID: 214376 [Multi-domain]  Cd Length: 240  Bit Score: 72.06  E-value: 3.31e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1590143752  56 IYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFhnAPEGNNLTS----FIRKLRKKIEPSPDNPQYILTVWGVGYKF 129
Cdd:CHL00148  160 IRLTGMEFSLLELLISKSGEIFSRATILKEVWGY--TPERHIDTRvvdvHISRLRAKLEDDPSNPDLILTARGTGYLF 235
 
Name Accession Description Interval E-value
Trans_reg_C pfam00486
Transcriptional regulatory protein, C terminal;
53-129 4.62e-37

Transcriptional regulatory protein, C terminal;


Pssm-ID: 425712 [Multi-domain]  Cd Length: 77  Bit Score: 121.08  E-value: 4.62e-37
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1590143752  53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDNPQYILTVWGVGYKF 129
Cdd:pfam00486   1 GEEVELTPKEFKLLELLAENPGRVVSREQLLEEVWGEDYDVDDNTVDVHISRLRKKLEDDPRDPRLIKTVRGVGYRL 77
trans_reg_C cd00383
DNA-binding effector domain of two-component system response regulators; Bacteria and some ...
 39-129 7.22e-37

DNA-binding effector domain of two-component system response regulators; Bacteria and some eukaryotes use two-component signal transduction systems to detect and respond to changes in the environment. The systems consists of a sensor histidine kinase and a response regulator. The former autophosphorylates a histidine residue on detecting an external stimulus. The phosphate is then transferred to an invariant aspartate residue in a highly conserved receiver domain of the response regulator. Phosphorylation activates a variable effector domain of the response regulator, which triggers the cellular response. This C-terminal effector domain belongs to the winged helix-turn-helix family of transcriptional regulators and contains DNA and RNA polymerase binding sites. Several dimers or monomers bind head to tail to small tandem repeats upstream of the genes. The RNA polymerase binding sites interact with the alpha or sigma subunit of RNA polymerase.


Pssm-ID: 294013 [Multi-domain]  Cd Length: 89  Bit Score: 121.05  E-value: 7.22e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  39 FDIDPLTRTFTNEeGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPdNPQY 118
Cdd:cd00383     1 LRLDPARREVTVD-GEEVELTPKEFELLELLARNPGRVVSREELLEAVWGYDYEVDDRTVDVHISRLRKKLEDDP-EPRL 78

                          90
                  ....*....|.
gi 1590143752 119 ILTVWGVGYKF 129
Cdd:cd00383    79 IKTVRGVGYRL 89
Trans_reg_C smart00862
Transcriptional regulatory protein, C terminal; This domain is almost always found associated ...
 53-129 3.70e-34

Transcriptional regulatory protein, C terminal; This domain is almost always found associated with the response regulator receiver domain. It may play a role in DNA binding.


Pssm-ID: 214866 [Multi-domain]  Cd Length: 76  Bit Score: 113.80  E-value: 3.70e-34
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1590143752   53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDnPQYILTVWGVGYKF 129
Cdd:smart00862   1 GEPIKLTPKEFRLLELLLRNPGRVVSREELLEAVWGDDEDVDDNTLDVHISRLRKKLEDDGD-PRLIETVRGVGYRL 76
CadC1 COG3710
DNA-binding winged helix-turn-helix (wHTH) domain [Transcription];
38-132 4.98e-25

DNA-binding winged helix-turn-helix (wHTH) domain [Transcription];


Pssm-ID: 442924 [Multi-domain]  Cd Length: 106  Bit Score: 91.50  E-value: 4.98e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  38 GFDIDPLTRTFTNEeGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGfHNAPEGNNLTSFIRKLRKKIEPSPDNPQ 117
Cdd:COG3710     7 DFRLDPARRELLRD-GEPVRLSPRAFDLLLLLLEHPGRVVSRDELLAAVWP-GRVVSDNSLTQAISRLRKALGDDGLEPR 84

                          90
                  ....*....|....*
gi 1590143752 118 YILTVWGVGYKFNEE 132
Cdd:COG3710    85 LIRTVPRRGYRLVAP 99
OmpR COG0745
DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain ...
 41-121 1.65e-20

DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription];


Pssm-ID: 440508 [Multi-domain]  Cd Length: 204  Bit Score: 82.70  E-value: 1.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  41 IDPLTRTFTNEeGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFhNAPEGNNLTSFIRKLRKKIEpspdnPQYIL 120
Cdd:COG0745   131 LDLAAREVTRD-GEPVELTPKEFRLLELLMRNPGRVVSREQLLEEVWGY-DYGDDRTVDVHISRLRKKLE-----DDLIE 203


                  .
gi 1590143752 121 T 121
Cdd:COG0745   204 T 204
orf27 CHL00148
Ycf27; Reviewed
 56-129 3.31e-16

Ycf27; Reviewed


Pssm-ID: 214376 [Multi-domain]  Cd Length: 240  Bit Score: 72.06  E-value: 3.31e-16
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1590143752  56 IYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFhnAPEGNNLTS----FIRKLRKKIEPSPDNPQYILTVWGVGYKF 129
Cdd:CHL00148  160 IRLTGMEFSLLELLISKSGEIFSRATILKEVWGY--TPERHIDTRvvdvHISRLRAKLEDDPSNPDLILTARGTGYLF 235
ompR PRK09468
osmolarity response regulator; Provisional
 39-129 1.27e-13

osmolarity response regulator; Provisional


Pssm-ID: 181883 [Multi-domain]  Cd Length: 239  Bit Score: 65.00  E-value: 1.27e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  39 FDIDPLTRTFTnEEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDNPQY 118
Cdd:PRK09468  144 FKLNLGTRELF-RGDEPMPLTTGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRLIEEDPAHPRY 222

                          90
                  ....*....|.
gi 1590143752 119 ILTVWGVGYKF 129
Cdd:PRK09468  223 IQTVWGLGYVF 233
PRK10161 PRK10161
phosphate response regulator transcription factor PhoB;
35-130 2.27e-12

phosphate response regulator transcription factor PhoB;


Pssm-ID: 182277 [Multi-domain]  Cd Length: 229  Bit Score: 61.66  E-value: 2.27e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  35 QKKGFDIDPLT-RTFTNEegTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSP 113
Cdd:PRK10161  133 EMQGLSLDPTShRVMAGE--EPLEMGPTEFKLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGG 210

                          90
                  ....*....|....*..
gi 1590143752 114 DNpQYILTVWGVGYKFN 130
Cdd:PRK10161  211 HD-RMVQTVRGTGYRFS 226
PRK10529 PRK10529
DNA-binding transcriptional activator KdpE; Provisional
 41-129 5.64e-12

DNA-binding transcriptional activator KdpE; Provisional


Pssm-ID: 182522 [Multi-domain]  Cd Length: 225  Bit Score: 60.20  E-value: 5.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  41 IDPLTRTFTNEEgTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGfHNAPEGNN-LTSFIRKLRKKIEPSPDNPQYI 119
Cdd:PRK10529  136 VDLAARVIHRGE-EEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQVWG-PNAVEHSHyLRIYMGHLRQKLEQDPARPRHF 213

                          90
                  ....*....|
gi 1590143752 120 LTVWGVGYKF 129
Cdd:PRK10529  214 ITETGIGYRF 223
PRK11517 PRK11517
DNA-binding response regulator HprR;
27-133 4.17e-11

DNA-binding response regulator HprR;


Pssm-ID: 183172 [Multi-domain]  Cd Length: 223  Bit Score: 57.99  E-value: 4.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  27 YTPASFNQQKKGFDIDPlTRTFTNEEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLR 106
Cdd:PRK11517  118 HHALNSTLEISGLRMDS-VSQSVSRDNISITLTRKEFQLLWLLASRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLR 196

                          90       100
                  ....*....|....*....|....*..
gi 1590143752 107 KKIEpSPDNPQYILTVWGVGYKFNEEK 133
Cdd:PRK11517  197 AKVD-DPFPEKLIATIRGMGYSFVAVK 222
PRK09836 PRK09836
DNA-binding transcriptional activator CusR; Provisional
 41-127 7.55e-11

DNA-binding transcriptional activator CusR; Provisional


Pssm-ID: 182102 [Multi-domain]  Cd Length: 227  Bit Score: 57.24  E-value: 7.55e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  41 IDPLTRTFTnEEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDnPQYIL 120
Cdd:PRK09836  135 VDLVSRKVT-RSGTRITLTSKEFTLLEFFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFE-PKLIQ 212


                  ....*..
gi 1590143752 121 TVWGVGY 127
Cdd:PRK09836  213 TVRGVGY 219
PRK10153 PRK10153
DNA-binding transcriptional activator CadC; Provisional
 40-128 6.34e-09

DNA-binding transcriptional activator CadC; Provisional


Pssm-ID: 236658 [Multi-domain]  Cd Length: 517  Bit Score: 52.74  E-value: 6.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  40 DIDPLTRtftneEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWgfhnapEGNNLTSF-----IRKLRKKI-EPSP 113
Cdd:PRK10153   16 SENKISR-----QGREVTLEPRLIDLLVFFAQHSGEVLSRDELIDHVW------DRAIVTDHvvtqsISELRKSLkDGRE 84

                          90
                  ....*....|....*
gi 1590143752 114 DNPQYILTVWGVGYK 128
Cdd:PRK10153   85 DNPEYIVTVPKRGYK 99
PRK10710 PRK10710
DNA-binding transcriptional regulator BaeR; Provisional
 58-128 7.76e-09

DNA-binding transcriptional regulator BaeR; Provisional


Pssm-ID: 182665 [Multi-domain]  Cd Length: 240  Bit Score: 51.99  E-value: 7.76e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1590143752  58 LTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDNPQYILTVWGVGYK 128
Cdd:PRK10710  161 LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYR 231
PRK11173 PRK11173
two-component response regulator; Provisional
 31-129 1.48e-08

two-component response regulator; Provisional


Pssm-ID: 183013 [Multi-domain]  Cd Length: 237  Bit Score: 51.17  E-value: 1.48e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  31 SFNqqkkGFDIDPLTRTFTNEEGTSIYLTAKEFD-LLHFLMlHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKI 109
Cdd:PRK11173  138 KFN----GWELDINSRSLISPDGEQYKLPRSEFRaMLHFCE-NPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHF 212

                          90       100
                  ....*....|....*....|
gi 1590143752 110 EPSPDNPQYILTVWGVGYKF 129
Cdd:PRK11173  213 ESTPDTPEIIATIHGEGYRF 232
PRK10643 PRK10643
two-component system response regulator PmrA;
53-127 2.61e-08

two-component system response regulator PmrA;


Pssm-ID: 182612 [Multi-domain]  Cd Length: 222  Bit Score: 50.42  E-value: 2.61e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1590143752  53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSpdnpqYILTVWGVGY 127
Cdd:PRK10643  145 GQELILTPKEFALLSRLMLKAGSPVHREILYQDIYNWDDEPSSNTLEVHIHNLRDKVGKD-----RIRTVRGFGY 214
PRK10701 PRK10701
DNA-binding transcriptional regulator RstA; Provisional
 41-129 2.70e-08

DNA-binding transcriptional regulator RstA; Provisional


Pssm-ID: 236738 [Multi-domain]  Cd Length: 240  Bit Score: 50.41  E-value: 2.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  41 IDPLTRTFTnEEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDNPQYIL 120
Cdd:PRK10701  146 IDPVNRQVT-LAGEEISLSTADFDLLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIK 224


                  ....*....
gi 1590143752 121 TVWGVGYKF 129
Cdd:PRK10701  225 TVRNKGYLF 233
PRK13856 PRK13856
two-component response regulator VirG; Provisional
 46-130 5.16e-08

two-component response regulator VirG; Provisional


Pssm-ID: 172377 [Multi-domain]  Cd Length: 241  Bit Score: 49.81  E-value: 5.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  46 RTFTNEEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLY-------ENVWGfhnapegNNLTSFIRKLRKKIEPSPDNPQY 118
Cdd:PRK13856  144 RRLISEAGGEVKLTAGEFNLLVAFLEKPRDVLSREQLLiasrvreEEVYD-------RSIDVLILRLRRKLEQDPANPQL 216

                          90
                  ....*....|..
gi 1590143752 119 ILTVWGVGYKFN 130
Cdd:PRK13856  217 IKTARGAGYFFD 228
PRK10816 PRK10816
two-component system response regulator PhoP;
39-130 3.92e-06

two-component system response regulator PhoP;


Pssm-ID: 182755 [Multi-domain]  Cd Length: 223  Bit Score: 44.34  E-value: 3.92e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  39 FDIDpLTRTFTNEEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEpSPDNPQY 118
Cdd:PRK10816  132 FQVD-LSRRELSINDEVIKLTAFEYTIMETLIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQ-AQYPQEV 209

                          90
                  ....*....|..
gi 1590143752 119 ILTVWGVGYKFN 130
Cdd:PRK10816  210 ITTVRGQGYRFD 221
PRK12370 PRK12370
HilA/EilA family virulence transcriptional regulator;
56-130 5.82e-06

HilA/EilA family virulence transcriptional regulator;


Pssm-ID: 237080 [Multi-domain]  Cd Length: 553  Bit Score: 44.07  E-value: 5.82e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1590143752  56 IYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEgNNLTSFIRKLRKKIEPSPDNpQYILTVWGVGYKFN 130
Cdd:PRK12370   34 VNIPPKEYAVLVILLEAAGEIVSKNTLLDQVWGDAEVNE-ESLTRCIYALRRILSEDKEH-RYIETLYGQGYRFN 106
PRK10955 PRK10955
envelope stress response regulator transcription factor CpxR;
52-127 7.37e-06

envelope stress response regulator transcription factor CpxR;


Pssm-ID: 182864 [Multi-domain]  Cd Length: 232  Bit Score: 43.64  E-value: 7.37e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1590143752  52 EGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSPDNPQYILTVWGVGY 127
Cdd:PRK10955  151 DGQTLELTGTEFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWFKTLRGRGY 226
PRK15479 PRK15479
transcriptional regulator TctD;
58-127 8.37e-06

transcriptional regulator TctD;


Pssm-ID: 185376 [Multi-domain]  Cd Length: 221  Bit Score: 43.17  E-value: 8.37e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  58 LTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIEPSpdNPQyILTVWGVGY 127
Cdd:PRK15479  149 LTPREQALLTVLMYRRTRPVSRQQLFEQVFSLNDEVSPESIELYIHRLRKKLQGS--DVR-ITTLRGLGY 215
PRK10336 PRK10336
two-component system response regulator QseB;
41-131 1.25e-05

two-component system response regulator QseB;


Pssm-ID: 182387 [Multi-domain]  Cd Length: 219  Bit Score: 42.96  E-value: 1.25e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  41 IDPLTRTFTnEEGTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIepspdNPQYIL 120
Cdd:PRK10336  134 LDPGKRIAT-LAGEPLTLKPKEFALLELLMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKL-----GSDFIR 207

                          90
                  ....*....|.
gi 1590143752 121 TVWGVGYKFNE 131
Cdd:PRK10336  208 TVHGIGYTLGE 218
PRK11083 PRK11083
DNA-binding response regulator CreB; Provisional
 53-127 3.93e-05

DNA-binding response regulator CreB; Provisional


Pssm-ID: 236838 [Multi-domain]  Cd Length: 228  Bit Score: 41.49  E-value: 3.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1590143752  53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWgfHNAPEGNNLT--SFIRKLRKKI-----EPSPdnpqyILTVWGV 125
Cdd:PRK11083  150 GTPLTLTRYEFLLLKTLLLSPGRVFSRQQLMDIVW--EDAQDSYDRTvdTHIKTLRAKLrainpDLSP-----INTHRGM 222


                  ..
gi 1590143752 126 GY 127
Cdd:PRK11083  223 GY 224
PRK10766 PRK10766
two-component system response regulator TorR;
53-124 3.72e-04

two-component system response regulator TorR;


Pssm-ID: 182711 [Multi-domain]  Cd Length: 221  Bit Score: 38.48  E-value: 3.72e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1590143752  53 GTSIYLTAKEFDLLHFLMLHKGQVFTKDQLYENVWGFHNAPEGNNLTSFIRKLRKKIepspdNPQYILTVWG 124
Cdd:PRK10766  155 GEPIKLTKAEYELLVAFVTNPGQVLSRERLLRMLSHRVENPNDRTIDVLIRRLRHKL-----NPDLFVTQHG 221
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH