|
Name |
Accession |
Description |
Interval |
E-value |
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-434 |
5.08e-162 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 464.15 E-value: 5.08e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 1 MGKIHFigiggigV-------SALAKYYLKKGFQVFGSDLVSSEIIDSLKKQGARIFVGkHSGKNLARSTgLVIYSPAVN 73
Cdd:COG0773 4 IMHIHF-------IgiggigmSGLAEILLALGYKVSGSDLAESPMTERLEALGIPVFIG-HDAENIDDAD-LVVVSSAIP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 74 PGNPELKEARRRKLKIQSYPEALGQLTKEYFTIAVSGTHGKSTTTAMLGLLFIKAGFDPTIILGTKLKELGnSNCRVGKS 153
Cdd:COG0773 75 RDNPELVAARERGIPVLSRAEMLAELMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFG-TNARLGDG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 154 QYLIIEADEHFASFLNYWPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKIKSTV-Y 232
Cdd:COG0773 154 DYFVAEADESDGSFLHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRPViT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 233 YSLK---------------------QKEAKKLKSI-LRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHAWRRFe 290
Cdd:COG0773 234 YGFSedadyraeniridgggstfdvLRRGEELGEVeLNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRF- 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 291 thEIKIKGKKITLISDYGHHPTEVRVTLKAAREKYPKKKILCVFQPHQYQRTYYLFKDFVKVLKMApvDKVVITDIYdvA 370
Cdd:COG0773 313 --ELKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSRTRDFLDEFAEALSLA--DEVILLDIY--A 386
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1604555053 371 GREENDikKKVSAEKLVKAIG--GNKTIYVP-KKEILGYLEKNLEKGEVLIIMGAGDIYSLTLRLTE 434
Cdd:COG0773 387 AREKPI--PGVSSEDLAEAIRkrGKDVVYVPdLDELVEALAEIARPGDVVLTMGAGDIGGLGEKLLE 451
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
3-428 |
1.39e-130 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 384.35 E-value: 1.39e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 3 KIHFIGIGGIGVSALAKYYLKKGFQVFGSDLVSSEIIDSLKKQGARIFVGkHSGKNLARSTgLVIYSPAVNPGNPELKEA 82
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENATTKRLEALGIPIYIG-HSAENLDDAD-VVVVSAAIKDDNPEIVEA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 83 RRRKLKIQSYPEALGQLTKEYFTIAVSGTHGKSTTTAMLGLLFIKAGFDPTIILGTKLKELGnSNCRVGKSQYLIIEADE 162
Cdd:TIGR01082 79 KERGIPVIRRAEMLAELMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAG-TNARLGSGEYLVAEADE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 163 HFASFLNYWPRIIVLTAVEKDHLD-YYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKI--KSTVYYS----- 234
Cdd:TIGR01082 158 SDASFLHLQPNVAIVTNIEPDHLDtYGSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKAteQVITYGGsgeda 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 235 -------------------LKQKEAKKLKsiLRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHAWRRFethEIK 295
Cdd:TIGR01082 238 dyraeniqqsgaegkfsvrGKGKLYLEFT--LNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRRF---EIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 296 IKGKKITLISDYGHHPTEVRVTLKAAREKYPKKKILCVFQPHQYQRTYYLFKDFVKVLKMApvDKVVITDIYdvAGREEN 375
Cdd:TIGR01082 313 GEFGGVLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHRYSRTRDLFDDFAKVLSDA--DELILLDIY--AAGEEP 388
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1604555053 376 diKKKVSAEKLVKAIGGNK---TIYVPKKEILG-YLEKNLEKGEVLIIMGAGDIYSL 428
Cdd:TIGR01082 389 --INGIDGKSLARKITQLGkiePYFVPDLAELVeFLAAVLQSGDLILTMGAGDIIKL 443
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
1-428 |
4.74e-71 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 239.33 E-value: 4.74e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 1 MGKI--HFIGIGGIGVSALAKYYLKKGFQVFGSDLVSSEIIDSLKKQGARIFVGKHsgKNLARSTGLVIYSPAVNPGNPE 78
Cdd:PRK14573 2 MKSLfyHFIGIGGIGMSALAHILLDRGYSVSGSDLSEGKTVEKLKAKGARFFLGHQ--EEHVPEDAVVVYSSSISKDNVE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 79 LKEARRRKLKIQSYPEALGQLTKEYFTIAVSGTHGKSTTTAMLGLLFIKAGFDPTIILGtKLKELGnSNCRVGKSQYLII 158
Cdd:PRK14573 80 YLSAKSRGNRLVHRAELLAELMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIG-GLNQEG-LNGYSGSSEYFVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 159 EADEHFASFLNYWPRIIVLTAVEKDHLDYYK-NLKNIISAFKKYLGRLDKDGILIANKDdnnVLSLSRKIKSTVY----- 232
Cdd:PRK14573 158 EADESDGSLKHYTPEFSVITNIDNEHLSNFEgDRELLLASIQDFARKVQQINKCFYNGD---CPRLKGCLQGHSYgfsss 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 233 -----YSLKQKEAKKLKSI-----------LRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHAWRRFETHEIKi 296
Cdd:PRK14573 235 cdlhiLSYYQEGWRSYFSAkflgvvyqdieLNLVGMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRRLERKNSS- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 297 kgKKITLISDYGHHPTEVRVTLKAAREKYPKKKILCVFQPHQYQRTYYLFKDFVKVLKMApvDKVVITDIYDvAGREEND 376
Cdd:PRK14573 314 --ETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLRECLDSFPSAFQDA--DEVILTDVYS-AGEEPED 388
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1604555053 377 IkkkVSAEKLVKAIGGNKTI---YVPKKEILGYLEKNLEKGEVLIIMGAGDIYSL 428
Cdd:PRK14573 389 S---ISYQKLAEAISQSSIVkctYVPFHEIQRYLEQSIRVHDVCVSLGAGNIYTL 440
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
108-265 |
2.28e-19 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 85.82 E-value: 2.28e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 108 VSGTHGKSTTTAMLGLLFIKAGFdPTIILGTKLKELGNS------------NCRVGKSQYLIIEADEH------FASFLN 169
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGG-VIGTIGTYIGKSGNTtnnaiglpltlaEMVEAGAEYAVLEVSSHglgegrLSGLLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 170 ywPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDN---NVLSLSRKIKSTVY-YSLKQKEAKKLKS 245
Cdd:pfam08245 80 --PDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPygaFLIAKLKKAGVRVItYGIEGEADLRAAN 157
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1604555053 246 I----------------------LRAPGDHNISNALAALSVA 265
Cdd:pfam08245 158 IelssdgtsfdlftvpggeleieIPLLGRHNVYNALAAIAAA 199
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-434 |
5.08e-162 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 464.15 E-value: 5.08e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 1 MGKIHFigiggigV-------SALAKYYLKKGFQVFGSDLVSSEIIDSLKKQGARIFVGkHSGKNLARSTgLVIYSPAVN 73
Cdd:COG0773 4 IMHIHF-------IgiggigmSGLAEILLALGYKVSGSDLAESPMTERLEALGIPVFIG-HDAENIDDAD-LVVVSSAIP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 74 PGNPELKEARRRKLKIQSYPEALGQLTKEYFTIAVSGTHGKSTTTAMLGLLFIKAGFDPTIILGTKLKELGnSNCRVGKS 153
Cdd:COG0773 75 RDNPELVAARERGIPVLSRAEMLAELMRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFG-TNARLGDG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 154 QYLIIEADEHFASFLNYWPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKIKSTV-Y 232
Cdd:COG0773 154 DYFVAEADESDGSFLHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPRCGRPViT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 233 YSLK---------------------QKEAKKLKSI-LRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHAWRRFe 290
Cdd:COG0773 234 YGFSedadyraeniridgggstfdvLRRGEELGEVeLNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRRF- 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 291 thEIKIKGKKITLISDYGHHPTEVRVTLKAAREKYPKKKILCVFQPHQYQRTYYLFKDFVKVLKMApvDKVVITDIYdvA 370
Cdd:COG0773 313 --ELKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYSRTRDFLDEFAEALSLA--DEVILLDIY--A 386
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1604555053 371 GREENDikKKVSAEKLVKAIG--GNKTIYVP-KKEILGYLEKNLEKGEVLIIMGAGDIYSLTLRLTE 434
Cdd:COG0773 387 AREKPI--PGVSSEDLAEAIRkrGKDVVYVPdLDELVEALAEIARPGDVVLTMGAGDIGGLGEKLLE 451
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
3-428 |
1.39e-130 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 384.35 E-value: 1.39e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 3 KIHFIGIGGIGVSALAKYYLKKGFQVFGSDLVSSEIIDSLKKQGARIFVGkHSGKNLARSTgLVIYSPAVNPGNPELKEA 82
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENATTKRLEALGIPIYIG-HSAENLDDAD-VVVVSAAIKDDNPEIVEA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 83 RRRKLKIQSYPEALGQLTKEYFTIAVSGTHGKSTTTAMLGLLFIKAGFDPTIILGTKLKELGnSNCRVGKSQYLIIEADE 162
Cdd:TIGR01082 79 KERGIPVIRRAEMLAELMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAG-TNARLGSGEYLVAEADE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 163 HFASFLNYWPRIIVLTAVEKDHLD-YYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKI--KSTVYYS----- 234
Cdd:TIGR01082 158 SDASFLHLQPNVAIVTNIEPDHLDtYGSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKAteQVITYGGsgeda 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 235 -------------------LKQKEAKKLKsiLRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHAWRRFethEIK 295
Cdd:TIGR01082 238 dyraeniqqsgaegkfsvrGKGKLYLEFT--LNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRRF---EIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 296 IKGKKITLISDYGHHPTEVRVTLKAAREKYPKKKILCVFQPHQYQRTYYLFKDFVKVLKMApvDKVVITDIYdvAGREEN 375
Cdd:TIGR01082 313 GEFGGVLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHRYSRTRDLFDDFAKVLSDA--DELILLDIY--AAGEEP 388
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1604555053 376 diKKKVSAEKLVKAIGGNK---TIYVPKKEILG-YLEKNLEKGEVLIIMGAGDIYSL 428
Cdd:TIGR01082 389 --INGIDGKSLARKITQLGkiePYFVPDLAELVeFLAAVLQSGDLILTMGAGDIIKL 443
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
1-428 |
4.74e-71 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 239.33 E-value: 4.74e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 1 MGKI--HFIGIGGIGVSALAKYYLKKGFQVFGSDLVSSEIIDSLKKQGARIFVGKHsgKNLARSTGLVIYSPAVNPGNPE 78
Cdd:PRK14573 2 MKSLfyHFIGIGGIGMSALAHILLDRGYSVSGSDLSEGKTVEKLKAKGARFFLGHQ--EEHVPEDAVVVYSSSISKDNVE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 79 LKEARRRKLKIQSYPEALGQLTKEYFTIAVSGTHGKSTTTAMLGLLFIKAGFDPTIILGtKLKELGnSNCRVGKSQYLII 158
Cdd:PRK14573 80 YLSAKSRGNRLVHRAELLAELMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIG-GLNQEG-LNGYSGSSEYFVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 159 EADEHFASFLNYWPRIIVLTAVEKDHLDYYK-NLKNIISAFKKYLGRLDKDGILIANKDdnnVLSLSRKIKSTVY----- 232
Cdd:PRK14573 158 EADESDGSLKHYTPEFSVITNIDNEHLSNFEgDRELLLASIQDFARKVQQINKCFYNGD---CPRLKGCLQGHSYgfsss 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 233 -----YSLKQKEAKKLKSI-----------LRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHAWRRFETHEIKi 296
Cdd:PRK14573 235 cdlhiLSYYQEGWRSYFSAkflgvvyqdieLNLVGMHNVANAAAAMGIALTLGIDEGAIRNALKGFSGVQRRLERKNSS- 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 297 kgKKITLISDYGHHPTEVRVTLKAAREKYPKKKILCVFQPHQYQRTYYLFKDFVKVLKMApvDKVVITDIYDvAGREEND 376
Cdd:PRK14573 314 --ETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFSRLRECLDSFPSAFQDA--DEVILTDVYS-AGEEPED 388
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 1604555053 377 IkkkVSAEKLVKAIGGNKTI---YVPKKEILGYLEKNLEKGEVLIIMGAGDIYSL 428
Cdd:PRK14573 389 S---ISYQKLAEAISQSSIVkctYVPFHEIQRYLEQSIRVHDVCVSLGAGNIYTL 440
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
16-283 |
2.74e-32 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 127.50 E-value: 2.74e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 16 ALAKYYLKKGFQVFGSDLVSSEII--DSLKKQGARIFVGKHSGKNLARSTgLVIYSPAVNPGNPELKEARRRKLKIQSYP 93
Cdd:COG0771 18 AAARLLAKLGAEVTVSDDRPAPELaaAELEAPGVEVVLGEHPEELLDGAD-LVVKSPGIPPDHPLLKAARAAGIPVIGEI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 94 EALGQLTKEYFtIAVSGTHGKSTTTAMLGLLFIKAGFDPtiILGtklkelGNsncrVGKS-----------QYLIIEade 162
Cdd:COG0771 97 ELAYRLSPAPI-IAITGTNGKTTTTTLIGHILKAAGLRV--AVG------GN----IGTPlldlllepeppDVYVLE--- 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 163 hFASF-L----NYWPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKIKSTVY-YSLK 236
Cdd:COG0771 161 -LSSFqLettpSLRPDVAVILNITPDHLDRHGSMEAYAAAKARIFANQTPDDYAVLNADDPLTRALAEEAKARVVpFSLK 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1604555053 237 QK----------------EAKKLKSI--LRAPGDHNISNALAALSVARTLKIPDKISFQALSGYT 283
Cdd:COG0771 240 EPleggagledgklvdraSGEELLPVddLRLPGRHNLENALAALAAARALGVPPEAIREALRSFK 304
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
16-291 |
2.62e-27 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 113.20 E-value: 2.62e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 16 ALAKYYLKKGFQVFGSDLVSSEIIDSLKKQ-GARIFVGKHSGKNLARSTG--LVIYSPAVNPGNPELKEARRRKLKIQSY 92
Cdd:TIGR01087 13 AVARFLHKKGAEVTVTDLKPNEELEPSMGQlRLNEGSVLHTGLHLEDLNNadLVVKSPGIPPDHPLVQAAAKRGIPVVGD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 93 PEALGQLTKEYFtIAVSGTHGKSTTTAMLGLLFIKAGFdPTII---LGTKLKELGNSNcrvgKSQYLIIEadehFASFLN 169
Cdd:TIGR01087 93 IELFLRLVPLPV-VAITGTNGKTTTTSLLYHLLKAAGL-KAFLggnIGTPALEVLDQE----GAELYVLE----LSSFQL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 170 YW-----PRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKIKSTVYYSLKQKEAKK-- 242
Cdd:TIGR01087 163 ETteslrPEIALILNISEDHLDWHGSFEDYVAAKLKIFARQTEGDVAVLNADDPRFARLAQKSKAQVIWFSVEKDAERgl 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 243 --------LKS---ILRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHAWRRFET 291
Cdd:TIGR01087 243 cirdgglyLKPndlEGSLLGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLPHRLEY 302
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
16-274 |
1.46e-20 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 93.50 E-value: 1.46e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 16 ALAKYYLKKGFQVFGSDLVSS----EIIDSLKKQGARIFVGKHSGKNLARSTgLVIYSPAVNPGNPELKEARRRKLKIQS 91
Cdd:PRK14106 19 ALAKFLKKLGAKVILTDEKEEdqlkEALEELGELGIELVLGEYPEEFLEGVD-LVVVSPGVPLDSPPVVQAHKKGIEVIG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 92 YPEALGQLTKEyFTIAVSGTHGKSTTTAMLGLLFIKAGFDpTIILG-------TKLKELGNSNCRVGKSQYLIIEADEHF 164
Cdd:PRK14106 98 EVELAYRFSKA-PIVAITGTNGKTTTTTLLGEIFKNAGRK-TLVAGnigypliDAVEEYGEDDIIVAEVSSFQLETIKEF 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 165 AsflnywPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKIKSTVYY----------- 233
Cdd:PRK14106 176 K------PKVGCILNITPDHLDRHKTMENYIKAKARIFENQRPSDYTVLNYDDPRTRSLAKKAKARVIFfsrkslleegv 249
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1604555053 234 ---------SLKQKEAKKLKS-ILRAPGDHNISNALAALSVARTLKI-PDKI 274
Cdd:PRK14106 250 fvkngkiviSLGGKEEEVIDIdEIFIPGEHNLENALAATAAAYLLGIsPDVI 301
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
108-265 |
2.28e-19 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 85.82 E-value: 2.28e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 108 VSGTHGKSTTTAMLGLLFIKAGFdPTIILGTKLKELGNS------------NCRVGKSQYLIIEADEH------FASFLN 169
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGG-VIGTIGTYIGKSGNTtnnaiglpltlaEMVEAGAEYAVLEVSSHglgegrLSGLLK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 170 ywPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDN---NVLSLSRKIKSTVY-YSLKQKEAKKLKS 245
Cdd:pfam08245 80 --PDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPygaFLIAKLKKAGVRVItYGIEGEADLRAAN 157
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 1604555053 246 I----------------------LRAPGDHNISNALAALSVA 265
Cdd:pfam08245 158 IelssdgtsfdlftvpggeleieIPLLGRHNVYNALAAIAAA 199
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
94-334 |
4.48e-19 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 88.98 E-value: 4.48e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 94 EALGQLTKEYF--------TIAVSGTHGKSTTTAMLGLLFIKAGFdPTIILGT-------KLKELGN------------S 146
Cdd:COG0769 63 AALALLAAAFYghpsqklkLIGVTGTNGKTTTTYLLAQILRALGK-KTGLIGTvgngiggELIPSSLttpealdlqrllA 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 147 NCRVGKSQYLIIEA-----DEH------F--ASFLNywpriivLTaveKDHLDYYKNLKNIISAFKKYLGRLDKDGILIA 213
Cdd:COG0769 142 EMVDAGVTHVVMEVsshalDQGrvdgvrFdvAVFTN-------LT---RDHLDYHGTMEAYFAAKARLFDQLGPGGAAVI 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 214 NKDDNNVLSLSRKIKSTVY-YSLKQKEAKKLKSI---------------------LRAPGDHNISNALAALSVARTLKIP 271
Cdd:COG0769 212 NADDPYGRRLAAAAPARVItYGLKADADLRATDIelsadgtrftlvtpggevevrLPLIGRFNVYNALAAIAAALALGID 291
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1604555053 272 -DKIsFQALSGYTHAWRRFEtheiKIK-GKKITLISDYGHHPTEVRVTLKAAREkYPKKKILCVF 334
Cdd:COG0769 292 lEEI-LAALEKLKGVPGRME----RVDgGQGPTVIVDYAHTPDALENVLEALRP-HTKGRLIVVF 350
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
94-306 |
6.29e-15 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 76.29 E-value: 6.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 94 EALGQLTKEYF------TIAVSGTHGKSTTTAMLGLlfikagfdptiILGTK---LKELGNSN---------CRVGKS-Q 154
Cdd:COG0770 85 KALQQLAAAHRarfnipVIAITGSNGKTTTKEMLAA-----------VLSTKgkvLATPGNFNneigvpltlLRLPEDhE 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 155 YLIIE--ADeHF------ASFLNywPRIIVLTAVEKDHLDYYKNLKNIISA----FKKylgrLDKDGILIANKDDNNVLS 222
Cdd:COG0770 154 FAVLEmgMN-HPgeiaylARIAR--PDIAVITNIGPAHLEGFGSLEGIARAkgeiFEG----LPPGGVAVLNADDPLLAA 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 223 LSRKIKS-TVYYSLKQKEAKKLKSI---------------------LRAPGDHNISNALAALSVARTLKIPDKISFQALS 280
Cdd:COG0770 227 LAERAKArVLTFGLSEDADVRAEDIeldedgtrftlhtpggelevtLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLA 306
|
250 260
....*....|....*....|....*.
gi 1604555053 281 GYTHAWRRFethEIKIKGKKITLISD 306
Cdd:COG0770 307 AFQPVKGRL---EVIEGAGGVTLIDD 329
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
287-377 |
1.95e-12 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 62.75 E-value: 1.95e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 287 RRFEtheIKIKGKKITLISDYGHHPTEVRVTLKAAREKYPKKKILcVFQPHQyQRTYYLFKDFVKVLKMaPVDKVVITDI 366
Cdd:pfam02875 3 GRLE---VVGENNGVLVIDDYAHNPDAMEAALRALRNLFPGRLIL-VFGGMG-DRDAEFHALLGRLAAA-LADVVILTGD 76
|
90
....*....|.
gi 1604555053 367 YDVAGREENDI 377
Cdd:pfam02875 77 YPRAEDPGAII 87
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
94-334 |
3.03e-12 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 68.96 E-value: 3.03e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 94 EALGQLTKEYFT--------IAVSGTHGKSTT----TAMLGLLFIKAGFDPTIILGTKLKELGNSN-------------- 147
Cdd:PRK11929 95 KALGELAARWYGrpseqlslVAVTGTNGKTSCaqllAQLLTRLGKPCGSIGTLGARLDGRLIPGSLttpdaiilhrilar 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 148 CRVGKSQYLIIEADEH-------------FASFLNywpriivLTaveKDHLDYYKNLKNIISAFKKYLGRLDKDGILIAN 214
Cdd:PRK11929 175 MRAAGADAVAMEASSHgleqgrldglriaVAGFTN-------LT---RDHLDYHGTMQDYEEAKAALFSKLPGLGAAVIN 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 215 KDDNNVLSLSRKIKSTVYYSLKQKEA------------------------KKLKSILRAPGDHNISNALAALSVARTLKI 270
Cdd:PRK11929 245 ADDPAAARLLAALPRGLKVGYSPQNAgadvqardlratahgqvftlatpdGSYQLVTRLLGRFNVSNLLLVAAALKKLGL 324
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1604555053 271 PDKISFQALSGYTHAWRRFE--THEIKIKGKKITLisDYGHHPTEVRVTLKAAR--EKYPKKKILCVF 334
Cdd:PRK11929 325 PLAQIARALAAVSPVPGRMErvGPTAGAQGPLVVV--DYAHTPDALAKALTALRpvAQARNGRLVCVF 390
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
45-334 |
6.54e-12 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 66.96 E-value: 6.54e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 45 QGARIFVGKHSGKNLARSTGLVIYSPAVN---PGNPELKEARRRKlkiqsypeALGQLTKEYF--------TIAVSGTHG 113
Cdd:TIGR01085 24 KGTHVDGHDFIHDAIANGAVAVVVERDVDfyvAPVPVIIVPDLRH--------ALSSLAAAFYghpskklkVIGVTGTNG 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 114 KSTTTAMLGLLFIKAGfDPTIILGTKLKELGN----------------------SNCRVGKSQYLIIEADEHFASF---- 167
Cdd:TIGR01085 96 KTTTTSLIAQLLRLLG-KKTGLIGTIGYRLGGndliknpaalttpealtlqstlAEMVEAGAQYAVMEVSSHALAQgrvr 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 168 -LNYwpRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDD------NNVLSLSRKIKSTVYYSLKQKEA 240
Cdd:TIGR01085 175 gVRF--DAAVFTNLSRDHLDFHGTMENYFAAKASLFTELGLKRFAVINLDDeygaqfVKRLPKDITVSAITQPADGRAQD 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 241 KKLKSI---------------------LRAPGDHNISNALAALSVARTLKI--PDKI-----SFQALSGythawrRFETH 292
Cdd:TIGR01085 253 IKITDSgysfegqqftfetpageghlhTPLIGRFNVYNLLAALATLLHLGGidLEDIvaaleKFRGVPG------RMELV 326
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1604555053 293 EIkikGKKITLISDYGHHPTEVRVTLKAAReKYPKKKILCVF 334
Cdd:TIGR01085 327 DG---GQKFLVIVDYAHTPDALEKALRTLR-KHKDGRLIVVF 364
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
3-103 |
1.12e-11 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 60.33 E-value: 1.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 3 KIHFIGIGGIGVSALAKYYLKKGFQVFGSDlvsseIIDSLKKQGARIFVGkHSGKNlarstglviyspAVNPGNPELKEA 82
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSD-----FIESLIALGAAAVVG-HDAAN------------NISPDNPELEAA 62
|
90 100
....*....|....*....|.
gi 1604555053 83 RRRKLKIQSYPEALGQLTKEY 103
Cdd:pfam01225 63 KVPGIPVIDRREALAELAAAF 83
|
|
| murF |
TIGR01143 |
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the ... |
94-333 |
1.54e-11 |
|
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; This family consists of the strictly bacterial MurF gene of peptidoglycan biosynthesis. This enzyme is almost always UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, but in a few species, MurE adds lysine rather than diaminopimelate. This enzyme acts on the product from MurE activity, and so is also subfamily rather than equivalog. Staphylococcus aureus is an example of species in this MurF protein would differ. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273468 [Multi-domain] Cd Length: 417 Bit Score: 65.75 E-value: 1.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 94 EALGQLTKEY------FTIAVSGTHGKSTTTAMLGllfikagfdptIILGTK---LKELGNSNCRVG----------KSQ 154
Cdd:TIGR01143 59 EALQALARAKrakfsgKVIGITGSSGKTTTKEMLA-----------AILSHKykvFATPGNFNNEIGlpltllrapgDHD 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 155 YLIIE--ADE-----HFASFLNywPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDDNNVLSLSRKI 227
Cdd:TIGR01143 128 YAVLEmgASHpgeiaYLAEIAK--PDIAVITNIGPAHLEGFGSLEGIAEAKGEILQGLKENGIAVINADDPAFADLAKRL 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 228 KS--TVYYSLKQKEAKkLKSILRAP----------------------GDHNISNALAALSVARTLKIPDKISFQALSGYT 283
Cdd:TIGR01143 206 PNrnILSFGFEGGDFV-AKDISYSAlgstsftlvapggefevslpllGRHNVMNALAAAALALELGIPLEEIAEGLAELK 284
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1604555053 284 HAWRRFETHEIkikgKKITLISD-YGHHPTEVRVTLKAArEKYPKKKILCV 333
Cdd:TIGR01143 285 LVKGRFEVQTK----NGLTLIDDtYNANPDSMRAALDAL-ARFPGKKILVL 330
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
97-334 |
5.84e-11 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 64.00 E-value: 5.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 97 GQLTKEYFTIAVSGTHGKSTTTAMLGLLFIKAGFdPTIILGT------------------------KLKELGNSNCrvgk 152
Cdd:PRK00139 89 GHPSDKLKLIGVTGTNGKTTTAYLLAQILRLLGE-KTALIGTlgngiggelipsglttpdaldlqrLLAELVDAGV---- 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 153 sQYLIIEADEH-----------F--ASFLNywpriivLTaveKDHLDYYKNLKNIISAfKKylgRL--DKDGILIANKDD 217
Cdd:PRK00139 164 -TYAAMEVSSHaldqgrvdglkFdvAVFTN-------LS---RDHLDYHGTMEDYLAA-KA---RLfsELGLAAVINADD 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 218 NNvlslSRK-IKSTVYYSLKQKEAK-KLKSI----------------LRAPGDHNISNALAALSVARTLKIPDKISFQAL 279
Cdd:PRK00139 229 EV----GRRlLALPDAYAVSMAGADlRATDVeytdsgqtftlvteveSPLIGRFNVSNLLAALAALLALGVPLEDALAAL 304
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 1604555053 280 SGYTHAWRRFETheIKIkGKKITLISDYGHHPTEVRVTLKAAREkYPKKKILCVF 334
Cdd:PRK00139 305 AKLQGVPGRMER--VDA-GQGPLVIVDYAHTPDALEKVLEALRP-HAKGRLICVF 355
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
95-331 |
1.36e-07 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 53.94 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 95 ALGQLTKEY---FT---IAVSGTHGKSTTTAMLGLLFIKAGFDptiilGTKLKELGNSNCRVGKSQYLI-IEADEHFASF 167
Cdd:PRK11929 589 ALGRLATAWrarFSlpvVAITGSNGKTTTKEMIAAILAAWQGE-----DRVLATEGNFNNEIGVPLTLLrLRAQHRAAVF 663
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 168 ---LNY-----------WPRIIVLTAVEKDHLDYYKNLKNIISAFKKYLGRLDKDGILIANKDD------------NNVL 221
Cdd:PRK11929 664 elgMNHpgeiaylaaiaAPTVALVTNAQREHQEFMHSVEAVARAKGEIIAALPEDGVAVVNGDDpytaiwaklagaRRVL 743
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1604555053 222 SLSRKIKSTVYY-----SLKQKEAKKLK--------SI---LRAPGDHNISNALAALSVARTLKIPDKISFQALSGYTHA 285
Cdd:PRK11929 744 RFGLQPGADVYAekiakDISVGEAGGTRcqvvtpagSAevyLPLIGEHNLRNALAAIACALAAGASLKQIRAGLERFQPV 823
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1604555053 286 WRRFETHEIKikgKKITLISD-YGHHPTEVRVTLKAAREKYPKKKIL 331
Cdd:PRK11929 824 AGRMQRRRLS---CGTRIIDDtYNANPDSMRAAIDVLAELPNGPRAL 867
|
|
| |
