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Conserved domains on  [gi|1606147603|gb|TFR41263|]
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colanic acid biosynthesis glycosyltransferase WcaC [Escherichia coli]

Protein Classification

colanic acid biosynthesis glycosyltransferase WcaC( domain architecture ID 11499294)

colanic acid biosynthesis glycosyltransferase WcaC is involved in the biosynthesis of colanic acid, an exopolysaccharide

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WcaC TIGR04015
colanic acid biosynthesis glycosyl transferase WcaC; This gene is one of the glycosyl ...
 1-405 0e+00

colanic acid biosynthesis glycosyl transferase WcaC; This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.


:

Pssm-ID: 274919  Cd Length: 405  Bit Score: 899.73  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603   1 MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGKESVSHQNYPQVIKHTPRMTAMANIALFRLLNRDLFG 80
Cdd:TIGR04015   1 MNILQFNVRLAEGGAAGVALDLHQRALQKGLTSHFVYGYGKGGKKSVSHDNYPQVIKHTPRLTSIANIALFRFFNRDLFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  81 NFNELYRTITRTPGPVVLHFHVLHSYWLNLKSVVRFCEKVKNHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160
Cdd:TIGR04015  81 NLDNLYRTITRTPGPVVLHFHVLHSYWLNLAKVVAFCEKVKAHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 161 TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIINNGIDMATEAILADLPPVRETQG 240
Cdd:TIGR04015 161 TLDNYPPVKIDRAHQLVDGKRQRFRDMLALGCQFISPSQHVADAFNSLYGAGRCRIINNGIDVATEAILAELPPVPEGQG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 241 KPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHTFGKFSPFTAGNVVNHGFETDKRKLMSVLNQMDALVFSSRVDNYP 320
Cdd:TIGR04015 241 KPKIAVVAHDLRYDGKTNQRLVRDMMALGDKIELHTFGKFSPFTGTNVVNHGFETDKRKLMSALNQMDALVFSSRVDNYP 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 321 LILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEDVLQLVQLSKPEIAQAIFGTTLAEFSQRSRAAYSGQQMLEEYVN 400
Cdd:TIGR04015 321 LILCEALSIGVPVIATHSEAAQEVLAKSGGKTVSESEVLQLAQRSKPEIAQAVFGTTLEAFRARSREAYSGQQMLEEYVS 400


                  ....*
gi 1606147603 401 FYQNL 405
Cdd:TIGR04015 401 FYQNL 405
 
Name Accession Description Interval E-value
WcaC TIGR04015
colanic acid biosynthesis glycosyl transferase WcaC; This gene is one of the glycosyl ...
 1-405 0e+00

colanic acid biosynthesis glycosyl transferase WcaC; This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.


Pssm-ID: 274919  Cd Length: 405  Bit Score: 899.73  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603   1 MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGKESVSHQNYPQVIKHTPRMTAMANIALFRLLNRDLFG 80
Cdd:TIGR04015   1 MNILQFNVRLAEGGAAGVALDLHQRALQKGLTSHFVYGYGKGGKKSVSHDNYPQVIKHTPRLTSIANIALFRFFNRDLFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  81 NFNELYRTITRTPGPVVLHFHVLHSYWLNLKSVVRFCEKVKNHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160
Cdd:TIGR04015  81 NLDNLYRTITRTPGPVVLHFHVLHSYWLNLAKVVAFCEKVKAHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 161 TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIINNGIDMATEAILADLPPVRETQG 240
Cdd:TIGR04015 161 TLDNYPPVKIDRAHQLVDGKRQRFRDMLALGCQFISPSQHVADAFNSLYGAGRCRIINNGIDVATEAILAELPPVPEGQG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 241 KPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHTFGKFSPFTAGNVVNHGFETDKRKLMSVLNQMDALVFSSRVDNYP 320
Cdd:TIGR04015 241 KPKIAVVAHDLRYDGKTNQRLVRDMMALGDKIELHTFGKFSPFTGTNVVNHGFETDKRKLMSALNQMDALVFSSRVDNYP 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 321 LILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEDVLQLVQLSKPEIAQAIFGTTLAEFSQRSRAAYSGQQMLEEYVN 400
Cdd:TIGR04015 321 LILCEALSIGVPVIATHSEAAQEVLAKSGGKTVSESEVLQLAQRSKPEIAQAVFGTTLEAFRARSREAYSGQQMLEEYVS 400


                  ....*
gi 1606147603 401 FYQNL 405
Cdd:TIGR04015 401 FYQNL 405
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 1-405 1.93e-121

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 356.64  E-value: 1.93e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603   1 MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKggkesvshqnypqvikhtprmtamanialfrllNRDLFG 80
Cdd:cd03825     1 MKVLHINTVDLSGGAARAAYRLHQALLAYGIDSTMLVGRKK---------------------------------NLISKP 47

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  81 NFNElyrtitrtpgPVVLHFHVLHSYWLNLKSVVRFCekvknhkPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160
Cdd:cd03825    48 EFIE----------ADIIHLHWIHGGYLSLKALFKLL-------RRKPVVWTLHDMWPFTGGCHYPMECEGWKTGCGNCP 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 161 TLNNYPPVKIDRAHQLVAGKRQLFRemlALGCQFISPSQHVADAFNS--LYGPGRCRIINNGIDMA--TEAILADLPPVR 236
Cdd:cd03825   111 NLNSYPPAKKDLSRQLFRRKREALA---KKRLTIVAPSRWLADMVRRspLLKGLPVVVIPNGIDTEifAPVDKAKARKRL 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 237 ETQGkPKIAVVAHDLRYD--GKTNQQLVREMMALG--DKIELHTFGKFSPFTA---GNVVNHGFETDKRKLMSVLNQMDA 309
Cdd:cd03825   188 GIPQ-DKKVILFGAESVTkpRKGFDELIEALKLLAtkDDLLLVVFGKNDPQIVilpFDIISLGYIDDDEQLVDIYSAADL 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 310 LVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQ-KSGGKTVSEEDVlqlvqlskPEIAQAIFGTTL-----AEFSQ 383
Cdd:cd03825   267 FVHPSLADNLPNTLLEAMACGTPVVAFDTGGSPEIVQhGVTGYLVPPGDV--------QALAEAIEWLLAnpkerESLGE 338

                         410       420
                  ....*....|....*....|....*.
gi 1606147603 384 RSRAA----YSGQQMLEEYVNFYQNL 405
Cdd:cd03825   339 RARALaenhFDQRVQAQRYLELYKDL 364
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 304-405 7.50e-11

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 59.23  E-value: 7.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 304 LNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSG-GKTVSEEDVLQLVQ-----LSKPEIAQAifgtt 377
Cdd:COG0438    18 LAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGEtGLLVPPGDPEALAEailrlLEDPELRRR----- 92

                          90       100
                  ....*....|....*....|....*....
gi 1606147603 378 LAEFS-QRSRAAYSGQQMLEEYVNFYQNL 405
Cdd:COG0438    93 LGEAArERAEERFSWEAIAERLLALYEEL 121
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
285-373 8.66e-09

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 53.67  E-value: 8.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 285 AGNVVNHGFETDKRKLmsvLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEDVlqlvql 364
Cdd:pfam13692  55 EDRVIFTGFVEDLAEL---LAAADVFVLPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELVDGENGLLVPPGDP------ 125


                  ....*....
gi 1606147603 365 skPEIAQAI 373
Cdd:pfam13692 126 --EALAEAI 132
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 304-403 5.14e-06

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 48.49  E-value: 5.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 304 LNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKS-GGKTVSEEDVlqlvqlSKPEIAQAI--------F 374
Cdd:PRK15179  589 LTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLAGGAGEAVQEGvTGLTLPADTV------TAPDVAEALarihdmcaA 662

                          90       100       110
                  ....*....|....*....|....*....|
gi 1606147603 375 GTTLAEFSQ-RSRAAYSGQQMLEEYVNFYQ 403
Cdd:PRK15179  663 DPGIARKAAdWASARFSLNQMIASTVRCYQ 692
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 292-402 7.99e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 41.45  E-value: 7.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 292 GFetdkRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSGGktvsEEDVL----QLVQLSKP 367
Cdd:NF038011  373 GF----QKIDDLLPQVGLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQLIEGLDE----EDRALgaagEVVAIADP 444

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1606147603 368 E-IAQAIFGttLAEFSQRSRAA-----------YSGQQMLEEYVNFY 402
Cdd:NF038011  445 QaLARAALD--LLRDPQRWQAAqaaglarveryYTEELMFDRYRELY 489
 
Name Accession Description Interval E-value
WcaC TIGR04015
colanic acid biosynthesis glycosyl transferase WcaC; This gene is one of the glycosyl ...
 1-405 0e+00

colanic acid biosynthesis glycosyl transferase WcaC; This gene is one of the glycosyl transferases involved in the biosynthesis of colanic acid, an exopolysaccharide expressed in Enterobacteraceae species.


Pssm-ID: 274919  Cd Length: 405  Bit Score: 899.73  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603   1 MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGKESVSHQNYPQVIKHTPRMTAMANIALFRLLNRDLFG 80
Cdd:TIGR04015   1 MNILQFNVRLAEGGAAGVALDLHQRALQKGLTSHFVYGYGKGGKKSVSHDNYPQVIKHTPRLTSIANIALFRFFNRDLFG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  81 NFNELYRTITRTPGPVVLHFHVLHSYWLNLKSVVRFCEKVKNHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160
Cdd:TIGR04015  81 NLDNLYRTITRTPGPVVLHFHVLHSYWLNLAKVVAFCEKVKAHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 161 TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIINNGIDMATEAILADLPPVRETQG 240
Cdd:TIGR04015 161 TLDNYPPVKIDRAHQLVDGKRQRFRDMLALGCQFISPSQHVADAFNSLYGAGRCRIINNGIDVATEAILAELPPVPEGQG 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 241 KPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHTFGKFSPFTAGNVVNHGFETDKRKLMSVLNQMDALVFSSRVDNYP 320
Cdd:TIGR04015 241 KPKIAVVAHDLRYDGKTNQRLVRDMMALGDKIELHTFGKFSPFTGTNVVNHGFETDKRKLMSALNQMDALVFSSRVDNYP 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 321 LILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEDVLQLVQLSKPEIAQAIFGTTLAEFSQRSRAAYSGQQMLEEYVN 400
Cdd:TIGR04015 321 LILCEALSIGVPVIATHSEAAQEVLAKSGGKTVSESEVLQLAQRSKPEIAQAVFGTTLEAFRARSREAYSGQQMLEEYVS 400


                  ....*
gi 1606147603 401 FYQNL 405
Cdd:TIGR04015 401 FYQNL 405
GT4_WcaC-like cd03825
putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family ...
 1-405 1.93e-121

putative colanic acid biosynthesis glycosyl transferase WcaC and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Escherichia coli WcaC has been predicted to function in colanic acid biosynthesis. WcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis.


Pssm-ID: 340851 [Multi-domain]  Cd Length: 364  Bit Score: 356.64  E-value: 1.93e-121
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603   1 MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKggkesvshqnypqvikhtprmtamanialfrllNRDLFG 80
Cdd:cd03825     1 MKVLHINTVDLSGGAARAAYRLHQALLAYGIDSTMLVGRKK---------------------------------NLISKP 47

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  81 NFNElyrtitrtpgPVVLHFHVLHSYWLNLKSVVRFCekvknhkPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP 160
Cdd:cd03825    48 EFIE----------ADIIHLHWIHGGYLSLKALFKLL-------RRKPVVWTLHDMWPFTGGCHYPMECEGWKTGCGNCP 110

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 161 TLNNYPPVKIDRAHQLVAGKRQLFRemlALGCQFISPSQHVADAFNS--LYGPGRCRIINNGIDMA--TEAILADLPPVR 236
Cdd:cd03825   111 NLNSYPPAKKDLSRQLFRRKREALA---KKRLTIVAPSRWLADMVRRspLLKGLPVVVIPNGIDTEifAPVDKAKARKRL 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 237 ETQGkPKIAVVAHDLRYD--GKTNQQLVREMMALG--DKIELHTFGKFSPFTA---GNVVNHGFETDKRKLMSVLNQMDA 309
Cdd:cd03825   188 GIPQ-DKKVILFGAESVTkpRKGFDELIEALKLLAtkDDLLLVVFGKNDPQIVilpFDIISLGYIDDDEQLVDIYSAADL 266

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 310 LVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQ-KSGGKTVSEEDVlqlvqlskPEIAQAIFGTTL-----AEFSQ 383
Cdd:cd03825   267 FVHPSLADNLPNTLLEAMACGTPVVAFDTGGSPEIVQhGVTGYLVPPGDV--------QALAEAIEWLLAnpkerESLGE 338

                         410       420
                  ....*....|....*....|....*.
gi 1606147603 384 RSRAA----YSGQQMLEEYVNFYQNL 405
Cdd:cd03825   339 RARALaenhFDQRVQAQRYLELYKDL 364
GT4_PimA-like cd03801
phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 ...
 13-403 8.31e-17

phosphatidyl-myo-inositol mannosyltransferase; This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.


Pssm-ID: 340831 [Multi-domain]  Cd Length: 366  Bit Score: 81.04  E-value: 8.31e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  13 GGAAGVALDLHQRALQQGLASHFVYGYGKGGKESVSHQNYPQVIKHTPRMTAMANialfRLLNRdlfgnfnelYRTITRT 92
Cdd:cd03801    14 GGAERHVRELARALAARGHDVTVLTPADPGEPPEELEDGVIVPLLPSLAALLRAR----RLLRE---------LRPLLRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  93 PGPVVLHFHVLHSYWLNLksvvrfcekVKNHKPDVTLVWTLHDHWsvtgrcaftdgcegwktgcqkcptlnnyppvkIDR 172
Cdd:cd03801    81 RKFDVVHAHGLLAALLAA---------LLALLLGAPLVVTLHGAE--------------------------------PGR 119

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 173 AHQLVAGKRQLFREMLALG---CQFISPSQHVADAFNSLYGPGRCRI--INNGIDmATEAILADLPPVRETQGKPKIAVV 247
Cdd:cd03801   120 LLLLLAAERRLLARAEALLrraDAVIAVSEALRDELRALGGIPPEKIvvIPNGVD-LERFSPPLRRKLGIPPDRPVLLFV 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 248 AHDLRYDGKtnQQLVREMMALGDK---IELHTFG----------KFSPFTAGNVVNHGFETDKRkLMSVLNQMDALVFSS 314
Cdd:cd03801   199 GRLSPRKGV--DLLLEALAKLLRRgpdVRLVIVGgdgplraeleELELGLGDRVRFLGFVPDEE-LPALYAAADVFVLPS 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 315 RVDNYPLILCEALSIGVPVIATHSDAAREVLQ-KSGGKTVSEEDVLQLVQ-----LSKPEIAQAIfgttLAEFSQRSRAA 388
Cdd:cd03801   276 RYEGFGLVVLEAMAAGLPVVATDVGGLPEVVEdGEGGLVVPPDDVEALADallrlLADPELRARL----GRAARERVAER 351

                         410
                  ....*....|....*
gi 1606147603 389 YSGQQMLEEYVNFYQ 403
Cdd:cd03801   352 FSWERVAERLLDLYR 366
GT4_GT28_WabH-like cd03811
family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most ...
 107-398 9.52e-14

family 4 and family 28 glycosyltransferases similar to Klebsiella WabH; This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core.


Pssm-ID: 340839 [Multi-domain]  Cd Length: 351  Bit Score: 72.01  E-value: 9.52e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 107 WLNLKSVVRFCEKVKNHKPDVtlvwtLHDHWSVTGRCAFTDGCEGWKtgcqKCPTLNNYPPvKIDRAHQLVAGKRQLFRE 186
Cdd:cd03811    66 LGLLKAILKLKRILKRAKPDV-----VISFLGFATYIVAKLAAARSK----VIAWIHSSLS-KLYYLKKKLLLKLKLYKK 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 187 MLALGCQfispSQHVADAFNSLYGPGRCRI--INNGIDMATEAILADLPPVRETQGKPKIAVVAhdlRYDGKTNQQLVRE 264
Cdd:cd03811   136 ADKIVCV----SKGIKEDLIRLGPSPPEKIevIYNPIDIDRIRALAKEPILNEPEDGPVILAVG---RLDPQKGHDLLIE 208

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 265 MMAL----GDKIELHTFGKFSPFT-----------AGNVVNHGFETDKRKLMSvlnQMDALVFSSRVDNYPLILCEALSI 329
Cdd:cd03811   209 AFAKlrkkYPDVKLVILGDGPLREeleklakelglAERVIFLGFQSNPYPYLK---KADLFVLSSRYEGFPNVLLEAMAL 285

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 330 GVPVIATHSDAAREVLQKSGGKT-VSEEDVLQLVQLSKpEIAQAIfgttlAEFSQRSRAAYSGQQMLEEY 398
Cdd:cd03811   286 GTPVVSTDCPGPREILDDGENGLlVPDGDAAALAGILA-ALLQKK-----LDAALRERLAKAQEAVFREY 349
RfaB COG0438
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 304-405 7.50e-11

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440207 [Multi-domain]  Cd Length: 123  Bit Score: 59.23  E-value: 7.50e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 304 LNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSG-GKTVSEEDVLQLVQ-----LSKPEIAQAifgtt 377
Cdd:COG0438    18 LAAADVFVLPSRSEGFGLVLLEAMAAGLPVIATDVGGLPEVIEDGEtGLLVPPGDPEALAEailrlLEDPELRRR----- 92

                          90       100
                  ....*....|....*....|....*....
gi 1606147603 378 LAEFS-QRSRAAYSGQQMLEEYVNFYQNL 405
Cdd:COG0438    93 LGEAArERAEERFSWEAIAERLLALYEEL 121
GT4_WlbH-like cd03798
Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the ...
 87-390 6.26e-09

Bordetella parapertussis WlbH and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. Staphylococcus aureus CapJ may be involved in capsule polysaccharide biosynthesis. WlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS.


Pssm-ID: 340828 [Multi-domain]  Cd Length: 376  Bit Score: 57.39  E-value: 6.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  87 RTITRTPGPVVLHFHVL-----HSYWLNLKSVVRFCEKVKNHKPDVtlvwtLHDHWSVTGRCAFTdgCEGWKTGCQKCPT 161
Cdd:cd03798    53 LLGEAVPPRDGRRLLPLkprlrLLAPLRAPSLAKLLKRRRRGPPDL-----IHAHFAYPAGFAAA--LLARLYGVPYVVT 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 162 L-----NNYPPVK---------IDRAHQLVAGKRQLFREMLALGcqfispsqhvADAFNSlygpgrcRIINNGIDMATEA 227
Cdd:cd03798   126 EhgsdiNVFPPRSllrkllrwaLRRAARVIAVSKALAEELVALG----------VPRDRV-------DVIPNGVDPARFQ 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 228 ILADLPPVREtqGKPKIAVVAHDLRYDGktnQQLVREMMALGDK----IELHTFGKFSPFTA-----------GNVVNHG 292
Cdd:cd03798   189 PEDRGLGLPL--DAFVILFVGRLIPRKG---IDLLLEAFARLAKarpdVVLLIVGDGPLREAlralaedlglgDRVTFTG 263

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 293 FeTDKRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSG-GKTVSEED-------VLQLVQL 364
Cdd:cd03798   264 R-LPHEQVPAYYRACDVFVLPSRHEGFGLVLLEAMACGLPVVATDVGGIPEVVGDPEtGLLVPPGDadalaaaLRRALAE 342

                         330       340       350
                  ....*....|....*....|....*....|..
gi 1606147603 365 S-KPEIAQAIFGTTLAEFS-----QRSRAAYS 390
Cdd:cd03798   343 PyLRELGEAARARVAERFSwvkaaDRIAAAYR 374
Glyco_trans_1_4 pfam13692
Glycosyl transferases group 1;
285-373 8.66e-09

Glycosyl transferases group 1;


Pssm-ID: 463957 [Multi-domain]  Cd Length: 138  Bit Score: 53.67  E-value: 8.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 285 AGNVVNHGFETDKRKLmsvLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEDVlqlvql 364
Cdd:pfam13692  55 EDRVIFTGFVEDLAEL---LAAADVFVLPSLYEGFGLKLLEAMAAGLPVVATDVGGIPELVDGENGLLVPPGDP------ 125


                  ....*....
gi 1606147603 365 skPEIAQAI 373
Cdd:pfam13692 126 --EALAEAI 132
GT4_WbnK-like cd03807
Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 ...
 303-402 3.83e-08

Shigella dysenteriae WbnK and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.


Pssm-ID: 340836 [Multi-domain]  Cd Length: 362  Bit Score: 54.63  E-value: 3.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 303 VLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEDVLQLVQLSkpeIAQAIFGTTLAEFS 382
Cdd:cd03807   261 LLPAMDIFVLSSRTEGFPNALLEAMACGLPVVATDVGGAAELVDDGTGFLVPAGDPQALADAI---RALLEDPEKRARLG 337

                          90       100
                  ....*....|....*....|....
gi 1606147603 383 QRSRA----AYSGQQMLEEYVNFY 402
Cdd:cd03807   338 RAARErianEFSIDAMVRRYETLY 361
GT4_UGDG-like cd03817
UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most ...
 177-402 7.52e-08

UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins; This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.


Pssm-ID: 340844 [Multi-domain]  Cd Length: 372  Bit Score: 53.82  E-value: 7.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 177 VAGKRQLFREMLALGCQFISPSQHVADAFNSlYGPGRC-RIINNGIDMA------TEAILADLPPvreTQGKPKIAVVAh 249
Cdd:cd03817   134 KAVVRKLVRRFYNHTDAVIAPSEKIKDTLRE-YGVKGPiEVIPNGIDLDkfekplNTEERRKLGL---PPDEPILLYVG- 208

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 250 dlRYDGKTNQQLVREMMAL------------GDKIELHTFGKFSPFT--AGNVVNHGFeTDKRKLMSVLNQMDALVFSSR 315
Cdd:cd03817   209 --RLAKEKNIDFLLRAFAElkkepniklvivGDGPEREELKELARELglADKVIFTGF-VPREELPEYYKAADLFVFAST 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 316 VDNYPLILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEDVLQLVQLSKPEIAQAIFGTTLAEFSQRSRAAYSGQQML 395
Cdd:cd03817   286 TETQGLVYLEAMAAGLPVVAAKDPAASELVEDGENGFLFEPNDETLAEKLLHLRENLELLRKLSKNAEISAREFAFAKSV 365


                  ....*..
gi 1606147603 396 EEYVNFY 402
Cdd:cd03817   366 EKLYEEV 372
GT4_ExpE7-like cd03823
glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 ...
 10-402 4.94e-06

glycosyltransferase ExpE7 and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).


Pssm-ID: 340850 [Multi-domain]  Cd Length: 357  Bit Score: 48.09  E-value: 4.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  10 LAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGKESVSHQnypqvikHTPRMTAMANIALFRLlnRDLFGNFNELYRti 89
Cdd:cd03823    28 LVAEGHEVAVLTAGVGPPGQATVARSVVRYRRAPDETLPLA-------LKRRGYELFETYNPGL--RRLLARLLEDFR-- 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  90 trtpgPVVLHFHVLhsywLNL-KSVVRFCEKVKnhkpdVTLVWTLHDHWSvtgrcaftdgcegwktgcqKCPtlnnyppv 168
Cdd:cd03823    97 -----PDVVHTHNL----SGLgASLLDAARDLG-----IPVVHTLHDYWL-------------------LCP-------- 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 169 kidRAHQLVAGKRQlfremlalgcqFISPSQHVADAF-NSLYGPGRCRIINNGIDMAteaiLADLPPVRETQGKPKIAVV 247
Cdd:cd03823   136 ---RQFLFKKGGDA-----------VLAPSRFTANLHeANGLFSARISVIPNAVEPD----LAPPPRRRPGTERLRFGYI 197

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 248 AHDLRYDG-----KTNQQLVREMmalgdkIELHTFGKFS------PFTAGNVVNHG-FETDKRKlmSVLNQMDALVFSSR 315
Cdd:cd03823   198 GRLTEEKGidllvEAFKRLPRED------IELVIAGHGPlsderqIEGGRRIAFLGrVPTDDIK--DFYEKIDVLVVPSI 269

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 316 -VDNYPLILCEALSIGVPVIATHSDAAREVLQ-KSGGKTVSEEDVLQLV----QLSKPEIAQAifgttLAEFSQRSRAAY 389
Cdd:cd03823   270 wPEPFGLVVREAIAAGLPVIASDLGGIAELIQpGVNGLLFAPGDAEDLAaamrRLLTDPALLE-----RLRAGAEPPRST 344

                         410
                  ....*....|...
gi 1606147603 390 SGQqmLEEYVNFY 402
Cdd:cd03823   345 ESQ--AEEYLKLY 355
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 304-403 5.14e-06

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 48.49  E-value: 5.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 304 LNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKS-GGKTVSEEDVlqlvqlSKPEIAQAI--------F 374
Cdd:PRK15179  589 LTQFNAFLLLSRFEGLPNVLIEAQFSGVPVVTTLAGGAGEAVQEGvTGLTLPADTV------TAPDVAEALarihdmcaA 662

                          90       100       110
                  ....*....|....*....|....*....|
gi 1606147603 375 GTTLAEFSQ-RSRAAYSGQQMLEEYVNFYQ 403
Cdd:PRK15179  663 DPGIARKAAdWASARFSLNQMIASTVRCYQ 692
GT4_CapM-like cd03808
capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This ...
 286-344 2.52e-05

capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.


Pssm-ID: 340837 [Multi-domain]  Cd Length: 358  Bit Score: 46.05  E-value: 2.52e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1606147603 286 GNVVNHGFETDKRKLmsvLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREV 344
Cdd:cd03808   246 GRIEFLGFRSDVPEL---LAESDVFVLPSYREGLPRSLLEAMAAGRPVITTDVPGCREL 301
Glycos_transf_1 pfam00534
Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease ...
 286-345 3.16e-05

Glycosyl transferases group 1; Mutations in this domain of Swiss:P37287 lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family.


Pssm-ID: 425737 [Multi-domain]  Cd Length: 158  Bit Score: 43.80  E-value: 3.16e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 286 GNVVNHGFETDKRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVL 345
Cdd:pfam00534  58 GDNVIFLGFVSDEDLPELLKIADVFVLPSRYEGFGIVLLEAMACGLPVIASDVGGPPEVV 117
GT4_WavL-like cd03819
Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 ...
 209-347 5.03e-05

Vibrio cholerae WavL and similar sequences; This family is most closely related to the GT4 family of glycosyltransferases. WavL in Vibrio cholerae has been shown to be involved in the biosynthesis of the lipopolysaccharide core.


Pssm-ID: 340846 [Multi-domain]  Cd Length: 345  Bit Score: 45.04  E-value: 5.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 209 YGPGRCRIINNGIDM------ATEAILADLPPVRetqGKPKIAVVAhdlRYDGKTNQQLVREMMAL------------GD 270
Cdd:cd03819   147 VDPERIRVIPNGVDTdrfppeAEAEERAQLGLPE---GKPVVGYVG---RLSPEKGWLLLVDAAAElkdepdfrllvaGD 220

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1606147603 271 KIELHTFGKF--SPFTAGNVVNHGFETDKRKLMSvlnQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQK 347
Cdd:cd03819   221 GPERDEIRRLveRLGLRDRVTFTGFREDVPAALA---ASDVVVLPSLHEEFGRVALEAMACGTPVVATDVGGAREIVVH 296
Glyco_transf_4 pfam13439
Glycosyltransferase Family 4;
13-222 3.40e-04

Glycosyltransferase Family 4;


Pssm-ID: 463877 [Multi-domain]  Cd Length: 169  Bit Score: 40.98  E-value: 3.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  13 GGAAGVALDLHQRALQQGLASHfVYGYGKGGKESVSHQNYPQVIKHTPrmtamaniaLFRLLNRDLFGNFNELYRTITRT 92
Cdd:pfam13439   1 GGVERYVLELARALARRGHEVT-VVTPGGPGPLAEEVVRVVRVPRVPL---------PLPPRLLRSLAFLRRLRRLLRRE 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603  93 pGPVVLHFHVLHSYWLNLKSVVRfcekvknhKPDVTLVWTLHDHWsvtgrcaftdgcegwktgcqkcptlNNYPPVKIDR 172
Cdd:pfam13439  71 -RPDVVHAHSPFPLGLAALAARL--------RLGIPLVVTYHGLF-------------------------PDYKRLGARL 116

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1606147603 173 AHQLVAGKRqLFREMLALGCQFISPSQHVADAFNSLYG--PGRCRIINNGID 222
Cdd:pfam13439 117 SPLRRLLRR-LERRLLRRADRVIAVSEAVADELRRLYGvpPEKIRVIPNGVD 167
Glycosyltransferase_GTB-type cd01635
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 287-350 3.74e-04

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340816 [Multi-domain]  Cd Length: 235  Bit Score: 41.62  E-value: 3.74e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1606147603 287 NVVNHGFETDKRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSGG 350
Cdd:cd01635   168 RVVIIGGLVDDEVLELLLAAADVFVLPSRSEGFGLVLLEAMAAGKPVIATDVGGIPEFVVDGEN 231
PelF NF038011
GT4 family glycosyltransferase PelF; Proteins of this family are components of the ...
 292-402 7.99e-04

GT4 family glycosyltransferase PelF; Proteins of this family are components of the exopolysaccharide Pel transporter. It has been reported that PelF is a soluble glycosyltransferase that uses UDP-glucose as the substrate for the synthesis of exopolysaccharide Pel, whereas PelG is a Wzx-like and PST family exopolysaccharide transporter.


Pssm-ID: 411604 [Multi-domain]  Cd Length: 489  Bit Score: 41.45  E-value: 7.99e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 292 GFetdkRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSGGktvsEEDVL----QLVQLSKP 367
Cdd:NF038011  373 GF----QKIDDLLPQVGLMVLSSISEALPLVVLEAFAAGVPVVTTDVGSCRQLIEGLDE----EDRALgaagEVVAIADP 444

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1606147603 368 E-IAQAIFGttLAEFSQRSRAA-----------YSGQQMLEEYVNFY 402
Cdd:NF038011  445 QaLARAALD--LLRDPQRWQAAqaaglarveryYTEELMFDRYRELY 489
GT4_AmsD-like cd03820
amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most ...
 308-335 1.02e-03

amylovoran biosynthesis glycosyltransferase AmsD and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be responsible for the formation of galactose alpha-1,6 linkages in amylovoran.


Pssm-ID: 340847 [Multi-domain]  Cd Length: 351  Bit Score: 41.07  E-value: 1.02e-03
                          10        20
                  ....*....|....*....|....*...
gi 1606147603 308 DALVFSSRVDNYPLILCEALSIGVPVIA 335
Cdd:cd03820   257 SIFVLSSRYEGFPMVLLEAMAYGLPIIS 284
GT4-like cd03814
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 287-349 1.14e-03

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.


Pssm-ID: 340842 [Multi-domain]  Cd Length: 365  Bit Score: 40.74  E-value: 1.14e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1606147603 287 NVVNHGFETDkRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSG 349
Cdd:cd03814   249 DVIFTGFLTG-EELARAYASADVFVFPSRTETFGLVVLEAMASGLPVVAADAGGPRDIVRPGG 310
GT4-like cd03813
glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family ...
 211-402 1.55e-03

glycosyltransferase family 4 proteins; This family is most closely related to the GT4 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria, while some of them are also found in Archaea and eukaryotes.


Pssm-ID: 340841 [Multi-domain]  Cd Length: 474  Bit Score: 40.40  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 211 PGRCRIINNGIDMAteailaDLPPVRETQGKPKIAVVAHDLRY----DGKTnqqLVREMMALGDKIELHTFGKFSPFTAG 286
Cdd:cd03813   266 PDKTRVIPNGIDIQ------RFAPAREERPEKEPPVVGLVGRVvpikDVKT---FIRAFKLVRRAMPDAEGWLIGPEDED 336

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 287 --------NVVNHGFETDKRKLMSVLN------QMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLqksGGKT 352
Cdd:cd03813   337 peyaqeckRLVASLGLENKVKFLGFQNikeyypKLGLLVLTSISEGQPLVILEAMASGVPVVATDVGSCRELI---YGAD 413

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 353 VSEEDVLQLVQLSKPE-IAQAIF-----GTTLAEFSQRSRAA----YSGQQMLEEYVNFY 402
Cdd:cd03813   414 DALGQAGLVVPPADPEaLAEALIkllrdPELRQAFGEAGRKRvekyYTLEGMIDSYRKLY 473
GT4_MtfB-like cd03809
glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to ...
 296-373 2.53e-03

glycosyltransferases MtfB, WbpX, and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.


Pssm-ID: 340838 [Multi-domain]  Cd Length: 362  Bit Score: 39.65  E-value: 2.53e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1606147603 296 DKRKLMSVLNQMDALVFSSRVDNYPLILCEALSIGVPVIATHSDAAREVLQKSgGKTVSEEDVlqlvqlskPEIAQAI 373
Cdd:cd03809   259 SDEDLPALYRGARAFVFPSLYEGFGLPVLEAMACGTPVIASNISVLPEVAGDA-ALYFDPLDP--------ESIADAI 327
PRK09922 PRK09922
lipopolysaccharide 1,6-galactosyltransferase;
216-336 2.97e-03

lipopolysaccharide 1,6-galactosyltransferase;


Pssm-ID: 182148 [Multi-domain]  Cd Length: 359  Bit Score: 39.31  E-value: 2.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 216 IINNGIDMATEAIladlPPVREtqGKPKIAVVAHDLRYDGKTN-QQLVREMMALGDKIELHTFGKFSPFT---------- 284
Cdd:PRK09922  160 VIYNPVEIKTIII----PPPER--DKPAVFLYVGRLKFEGQKNvKELFDGLSQTTGEWQLHIIGDGSDFEkckaysrelg 233

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1606147603 285 -AGNVVNHGFetdKRKLMSVLNQ----MDALVFSSRVDNYPLILCEALSIGVPVIAT 336
Cdd:PRK09922  234 iEQRIIWHGW---QSQPWEVVQQkiknVSALLLTSKFEGFPMTLLEAMSYGIPCISS 287
GT4_AviGT4-like cd03802
UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is ...
 193-405 8.53e-03

UDP-Glc:tetrahydrobiopterin alpha-glucosyltransferase and similar proteins; This family is most closely related to the GT4 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant that accumulated a novel avilamycin derivative lacking the terminal eurekanate residue.


Pssm-ID: 340832 [Multi-domain]  Cd Length: 333  Bit Score: 38.04  E-value: 8.53e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 193 QFISPSQHVADAFNSLYGPGrcrIINNGIDmateaiLADLPPVRETQG-----------K-PKIAV-VAHdlrydgKTNQ 259
Cdd:cd03802   132 NYVSISDAQRAATPPIDYLT---VVHNGLD------PADYRFQPDPEDylaflgriapeKgLEDAIrVAR------RAGL 196

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1606147603 260 QLVremMALGDKIELHTFGKFSPFTAGNVVNHGFETDKRKlMSVLNQMDALVFSSRVDN-YPLILCEALSIGVPVIATHS 338
Cdd:cd03802   197 PLK---IAGKVRDEDYFYYLQEPLPGPRIEFIGEVGHDEK-QELLGGARALLFPINWDEpFGLVMIEAMACGTPVIAYRR 272

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1606147603 339 DAAREVLQKsgGKTVseedvlQLVQlSKPEIAQAIFGttLAEFS-----QRSRAAYSGQQMLEEYVNFYQNL 405
Cdd:cd03802   273 GGLPEVIQH--GETG------FLVD-SVEEMAEAIAN--IDRIDraacrRYAEDRFSAARMADRYEALYRKV 333
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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