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Conserved domains on  [gi|1631493464|gb|TJX79493|]
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shikimate kinase [Staphylococcus aureus]

Protein Classification

shikimate kinase( domain architecture ID 10087464)

shikimate kinase catalyzes the specific phosphorylation of the 3-hydroxylgroup of shikimic acid using ATP as a cosubstrate

EC:  2.7.1.71

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
7-159 9.54e-62

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


:

Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 187.76  E-value: 9.54e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   7 PIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEF-TCLQECINTADIIATGGGII 85
Cdd:cd00464     1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEReVLLLLLTKENAVIATGGGAV 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1631493464  86 ESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISE 159
Cdd:cd00464    81 LREENRRLLLENGIVVWLDASPEELLERLARDKTRPLLQDEDPERLRELLEEREPLYREVADLTIDTDELSPEE 154
 
Name Accession Description Interval E-value
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
7-159 9.54e-62

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 187.76  E-value: 9.54e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   7 PIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEF-TCLQECINTADIIATGGGII 85
Cdd:cd00464     1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEReVLLLLLTKENAVIATGGGAV 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1631493464  86 ESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISE 159
Cdd:cd00464    81 LREENRRLLLENGIVVWLDASPEELLERLARDKTRPLLQDEDPERLRELLEEREPLYREVADLTIDTDELSPEE 154
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
8-170 8.50e-57

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 175.70  E-value: 8.50e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIATGGGIIE 86
Cdd:COG0703     1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEEENaVIATGGGAVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  87 SEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQ-LNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELL 165
Cdd:COG0703    81 SPENRELLKEHGTVVYLDASPETLLERLRRDDNRPLLQGEDPRErLEELLAEREPLYREVADITVDTDGRSPEEVVDEIL 160

                  ....*
gi 1631493464 166 NLIKA 170
Cdd:COG0703   161 EALEE 165
SKI pfam01202
Shikimate kinase;
14-169 1.51e-56

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 174.69  E-value: 1.51e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  14 MGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIATGGGIIESEEAFN 92
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEHGlVIATGGGAVLSEENRD 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1631493464  93 FLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTI--KQLNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELLNLIK 169
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKRDKTRPLLQNKDPeeELLELLFEERDPLYEEAADIVIDTDESSPEEVATEILEALE 159
aroK PRK00131
shikimate kinase; Reviewed
1-146 6.82e-50

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 158.43  E-value: 6.82e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   1 MNHDKSpIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIA 79
Cdd:PRK00131    1 MLKGPN-IVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARHNlVIS 79
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1631493464  80 TGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRP-NANNKTIKQLNDLYCSRNLRYNEIA 146
Cdd:PRK00131   80 TGGGAVLREENRALLRERGTVVYLDASFEELLRRLRRDRNRPlLQTNDPKEKLRDLYEERDPLYEEVA 147
 
Name Accession Description Interval E-value
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
7-159 9.54e-62

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 187.76  E-value: 9.54e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   7 PIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEF-TCLQECINTADIIATGGGII 85
Cdd:cd00464     1 NIVLIGMMGAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEEGFRELEReVLLLLLTKENAVIATGGGAV 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1631493464  86 ESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISE 159
Cdd:cd00464    81 LREENRRLLLENGIVVWLDASPEELLERLARDKTRPLLQDEDPERLRELLEEREPLYREVADLTIDTDELSPEE 154
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
8-170 8.50e-57

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 175.70  E-value: 8.50e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIATGGGIIE 86
Cdd:COG0703     1 IVLIGMMGAGKSTVGRLLAKRLGLPFVDTDAEIEERAGMSIPEIFAEEGEAGFRELEREVLAELLEEENaVIATGGGAVL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  87 SEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQ-LNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELL 165
Cdd:COG0703    81 SPENRELLKEHGTVVYLDASPETLLERLRRDDNRPLLQGEDPRErLEELLAEREPLYREVADITVDTDGRSPEEVVDEIL 160

                  ....*
gi 1631493464 166 NLIKA 170
Cdd:COG0703   161 EALEE 165
SKI pfam01202
Shikimate kinase;
14-169 1.51e-56

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 174.69  E-value: 1.51e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  14 MGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIATGGGIIESEEAFN 92
Cdd:pfam01202   1 MGAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEGFRRLESEVLKELLAEHGlVIATGGGAVLSEENRD 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1631493464  93 FLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTI--KQLNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELLNLIK 169
Cdd:pfam01202  81 LLKERGIVIYLDAPLEVLLERLKRDKTRPLLQNKDPeeELLELLFEERDPLYEEAADIVIDTDESSPEEVATEILEALE 159
aroK PRK00131
shikimate kinase; Reviewed
1-146 6.82e-50

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 158.43  E-value: 6.82e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   1 MNHDKSpIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIA 79
Cdd:PRK00131    1 MLKGPN-IVLIGFMGAGKSTIGRLLAKRLGYDFIDTDHLIEARAGKSIPEIFEEEGEAAFRELEEEVLAELLARHNlVIS 79
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1631493464  80 TGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRP-NANNKTIKQLNDLYCSRNLRYNEIA 146
Cdd:PRK00131   80 TGGGAVLREENRALLRERGTVVYLDASFEELLRRLRRDRNRPlLQTNDPKEKLRDLYEERDPLYEEVA 147
PRK13946 PRK13946
shikimate kinase; Provisional
4-131 2.45e-28

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 103.85  E-value: 2.45e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   4 DKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEftclQECI-----NTADII 78
Cdd:PRK13946    9 GKRTVVLVGLMGAGKSTVGRRLATMLGLPFLDADTEIERAARMTIAEIFAAYGEPEFRDLE----RRVIarllkGGPLVL 84
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1631493464  79 ATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRP---NANNK-TIKQL 131
Cdd:PRK13946   85 ATGGGAFMNEETRAAIAEKGISVWLKADLDVLWERVSRRDTRPllrTADPKeTLARL 141
PRK13947 PRK13947
shikimate kinase; Provisional
8-121 1.63e-26

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 98.63  E-value: 1.63e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTClqeCINTAD----IIATGGG 83
Cdd:PRK13947    4 IVLIGFMGTGKTTVGKRVATTLSFGFIDTDKEIEKMTGMTVAEIFEKDGEVRFRSEEKLL---VKKLARlknlVIATGGG 80
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1631493464  84 IIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRP 121
Cdd:PRK13947   81 VVLNPENVVQLRKNGVVICLKARPEVILRRVGKKKSRP 118
PRK13949 PRK13949
shikimate kinase; Provisional
7-144 3.27e-26

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 97.88  E-value: 3.27e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   7 PIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIATGGGII 85
Cdd:PRK13949    3 RIFLVGYMGAGKTTLGKALARELGLSFIDLDFFIENRFHKTVGDIFAERGEAVFRELERNMLHEVAEFEDvVISTGGGAP 82
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1631493464  86 ESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPH-RPNANNKTIKQLNDLYCS----RNLRYNE 144
Cdd:PRK13949   83 CFFDNMELMNASGTTVYLKVSPEVLFVRLRLAKQqRPLLKGKSDEELLDFIIEalekRAPFYRQ 146
aroK PRK05057
shikimate kinase AroK;
4-146 2.47e-25

shikimate kinase AroK;


Pssm-ID: 235335 [Multi-domain]  Cd Length: 172  Bit Score: 95.55  E-value: 2.47e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   4 DKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTADII-ATGG 82
Cdd:PRK05057    3 EKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADIGWVFDVEGEEGFRDREEKVINELTEKQGIVlATGG 82
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1631493464  83 GIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQ-LNDLYCSRNLRYNEIA 146
Cdd:PRK05057   83 GSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQVDDPREvLEALANERNPLYEEIA 147
aroL PRK03731
shikimate kinase AroL;
7-146 8.87e-21

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 83.84  E-value: 8.87e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   7 PIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIE 86
Cdd:PRK03731    4 PLFLVGARGCGKTTVGMALAQALGYRFVDTDQWLQSTSNMTVAEIVEREGWAGFRARESAALEAVTAPSTVIATGGGIIL 83
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1631493464  87 SEEAFNFLKNQKNIIWLDCNIDIIYSRINDDP---HRPNANNKTI-KQLNDLYCSRNLRYNEIA 146
Cdd:PRK03731   84 TEENRHFMRNNGIVIYLCAPVSVLANRLEANPeedQRPTLTGKPIsEEVAEVLAEREALYREVA 147
PRK13948 PRK13948
shikimate kinase; Provisional
10-114 2.00e-20

shikimate kinase; Provisional


Pssm-ID: 184413 [Multi-domain]  Cd Length: 182  Bit Score: 83.30  E-value: 2.00e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  10 LIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-IIATGGGIIESE 88
Cdd:PRK13948   15 LAGFMGTGKSRIGWELSRALMLHFIDTDRYIERVTGKSIPEIFRHLGEAYFRRCEAEVVRRLTRLDYaVISLGGGTFMHE 94
                          90       100
                  ....*....|....*....|....*.
gi 1631493464  89 EAFNFLKNQKNIIWLDCNIDIIYSRI 114
Cdd:PRK13948   95 ENRRKLLSRGPVVVLWASPETIYERT 120
PRK13951 PRK13951
bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;
8-165 2.03e-20

bifunctional shikimate kinase AroK/3-dehydroquinate synthase AroB;


Pssm-ID: 172457 [Multi-domain]  Cd Length: 488  Bit Score: 87.27  E-value: 2.03e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECI-NTADIIATGGGIIE 86
Cdd:PRK13951    3 IFLVGMMGSGKSTIGKRVSEVLDLQFIDMDEEIERREGRSVRRIFEEDGEEYFRLKEKELLRELVeRDNVVVATGGGVVI 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  87 SEEAFNFLKnQKNIIWLDCNIDIIYSRINDDPHRPNANNKtiKQLNDLYCSRNLRYNEiaFKKFDSHLL----SISEIYY 162
Cdd:PRK13951   83 DPENRELLK-KEKTLFLYAPPEVLMERVTTENRPLLREGK--ERIREIWERRKQFYTE--FRGIDTSKLneweTTALVVL 157

                  ...
gi 1631493464 163 ELL 165
Cdd:PRK13951  158 EAL 160
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
8-103 1.08e-18

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 81.15  E-value: 1.08e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD--IIATGGGII 85
Cdd:PRK08154  136 IALIGLRGAGKSTLGRMLAARLGVPFVELNREIEREAGLSVSEIFALYGQEGYRRLERRALERLIAEHEemVLATGGGIV 215
                          90
                  ....*....|....*...
gi 1631493464  86 ESEEAFNFLKNQKNIIWL 103
Cdd:PRK08154  216 SEPATFDLLLSHCYTVWL 233
PRK14021 PRK14021
bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional
1-146 1.98e-14

bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional


Pssm-ID: 184458 [Multi-domain]  Cd Length: 542  Bit Score: 69.89  E-value: 1.98e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   1 MNHDKSPI-ILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTAD-II 78
Cdd:PRK14021    1 GKPTRRPQaVIIGMMGAGKTRVGKEVAQMMRLPFADADVEIEREIGMSIPSYFEEYGEPAFREVEADVVADMLEDFDgIF 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1631493464  79 ATGGG---IIESEEAF-NFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIA 146
Cdd:PRK14021   81 SLGGGapmTPSTQHALaSYIAHGGRVVYLDADPKEAMERANRGGGRPMLNGDANKRWKKLFKQRDPVFRQVA 152
PLN02199 PLN02199
shikimate kinase
10-114 6.42e-14

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 67.80  E-value: 6.42e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  10 LIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLT-IPEIFSKHGEQYFRNLEFTCLQECINTAD-IIATGGGIIes 87
Cdd:PLN02199  107 LVGMMGSGKTTVGKLMSKVLGYTFFDCDTLIEQAMNGTsVAEIFVHHGENFFRGKETDALKKLSSRYQvVVSTGGGAV-- 184
                          90       100
                  ....*....|....*....|....*...
gi 1631493464  88 EEAFNFLKNQKNI-IWLDCNIDIIYSRI 114
Cdd:PLN02199  185 IRPINWKYMHKGIsIWLDVPLEALAHRI 212
PRK00625 PRK00625
shikimate kinase; Provisional
8-167 1.19e-12

shikimate kinase; Provisional


Pssm-ID: 134335 [Multi-domain]  Cd Length: 173  Bit Score: 62.47  E-value: 1.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIP----EIFSKHGEQYFRNLEFTCLQECINTADIIATGGG 83
Cdd:PRK00625    3 IFLCGLPTVGKTSFGKALAKFLSLPFFDTDDLIVSNYHGALYsspkEIYQAYGEEGFCREEFLALTSLPVIPSIVALGGG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464  84 IIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDP------HRPNANNKTIKQLNDL--YCSRNLRYNEIAFkkFDSH-L 154
Cdd:PRK00625   83 TLMIEPSYAHIRNRGLLVLLSLPIATIYQRLQKRGlperlkHAPSLEEILSQRIDRMrsIADYIFSLDHVAE--TSSEsL 160
                         170
                  ....*....|...
gi 1631493464 155 LSISEIYYELLNL 167
Cdd:PRK00625  161 MRACQSFCTLLLS 173
AAA_18 pfam13238
AAA domain;
8-132 6.99e-05

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 40.49  E-value: 6.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGE--QYFRNLEFTCLQECINTAD----IIATG 81
Cdd:pfam13238   1 ILITGTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPETRESKRldEDKLDRLLDLLEENAALEEggnlIIDGH 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1631493464  82 GGIIESEEAFnflknQKNIIWLDCNIDIIYSRINDDPHRPN--ANNKTIKQLN 132
Cdd:pfam13238  81 LAELEPERAK-----DLVGIVLRASPEELLERLEKRGYEEAkiKENEEAEILG 128
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
8-37 5.30e-04

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 38.74  E-value: 5.30e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDID 37
Cdd:COG0645     2 ILVCGLPGSGKSTLARALAERLGAVRLRSD 31
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
8-39 1.31e-03

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 37.42  E-value: 1.31e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSY 39
Cdd:COG3265     4 IVVMGVSGSGKSTVGQALAERLGWPFIDGDDF 35
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
8-39 3.00e-03

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 36.46  E-value: 3.00e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDIDSY 39
Cdd:cd02021     2 IVVMGVSGSGKSTVGKALAERLGAPFIDGDDL 33
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
8-54 8.78e-03

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 34.88  E-value: 8.78e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1631493464   8 IILIGFMGTGKSTIGKYVADEQNLSFIDI------DSYIEEKYKLTIpEIFSK 54
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEIsgselvSKYVGESEKRLR-ELFEA 52
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
8-108 9.84e-03

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 35.19  E-value: 9.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1631493464   8 IILI-GFMGTGKSTIGKYVADEQNLSFID--IDSYIEEKYKLTiPEIFSKHGEQYFRNL-EFTCLQECIN------TADI 77
Cdd:COG1102     2 VITIsREPGSGGTTIAKRLAEKLGLPLYDgeILREAAKERGLS-EEEFEKLDEKAPSLLyRDTAEEDEIDraldkvIREL 80
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1631493464  78 IATGGGIIESEEAFNFLKNQKNI--IWLDCNID 108
Cdd:COG1102    81 ARKGNCVIVGRLADWILRDRPNVlkVFLTAPLE 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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