|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
13-401 |
0e+00 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 782.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 13 DDLEYQLDTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAV 92
Cdd:PRK08133 1 DDDSLGFDTLAVRAGQLRSPFGEHSEALFLTSSFVFESAAEAAARFAGEEPGNIYSRFTNPTVTMFQERLAALEGAEACV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 93 ATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLA 172
Cdd:PRK08133 81 ATASGMAAILAVVMALLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 173 EIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSVVRTLGPS 252
Cdd:PRK08133 161 ELADIAALAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGFLRTAGPT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 253 MSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAW 332
Cdd:PRK08133 241 LSPFNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKGGREAAW 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1660651604 333 KVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK08133 321 RVIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGLA 389
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
17-403 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 603.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 17 YQLDTLAIRTGH-TRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATS 95
Cdd:COG0626 1 MGPATRAVHAGRdPDPQTGAVSPPIYLTSTFVFPSAEALAARFAGEEGGYIYSRYGNPTRRALEEALAALEGGEAALAFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 96 SGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIA 175
Cdd:COG0626 81 SGMAAISAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 176 DIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLL-EEVFSVVRTLGPSMS 254
Cdd:COG0626 161 DIAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELaERLRFLQNALGAVLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 255 PFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKV 334
Cdd:COG0626 241 PFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGREAARRF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1660651604 335 IDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLDLI 403
Cdd:COG0626 321 LDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
20-400 |
0e+00 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 564.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 20 DTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 99
Cdd:TIGR01325 1 ATLAVRGGMLRSGFEETAEALYLTSGYVYDSAAVAAKRFAGELPGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 100 AILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQA 179
Cdd:TIGR01325 81 AIFAALMALLGAGDHVVASRSLFGSCFVVCSEILPRFGVQTVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 180 LADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSV-VRTLGPSMSPFNA 258
Cdd:TIGR01325 161 VAELAHAAGAKVVVDNVFATPLLQQPLKLGADVVVYSATKHIDGQGRVLGGAILGSEEYMDEPVQKlLRHTGPAMSPFNA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 259 WIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGeREGAWKVIDNT 338
Cdd:TIGR01325 241 WVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYPGLPSHPQHELAKRQMSGGGTVVTFDLDC-RQAAFKVLDAM 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1660651604 339 KFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:TIGR01325 320 RLVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVGLEDVDDLIADIDRAL 381
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
20-401 |
5.58e-180 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 505.61 E-value: 5.58e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 20 DTLAIRTGHTRSF-EGEHGEPIFLTSSFVYenaaeaaaKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGM 98
Cdd:pfam01053 1 DTLAVHAGQRPDPqTGAVSVPIYLTSTYVF--------DFAGEEGGYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 99 GAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQ 178
Cdd:pfam01053 73 AAITAAILALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 179 ALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQ-LLEEVFSVVRTLGPSMSPFN 257
Cdd:pfam01053 153 AIAKLAKKHGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEeLGKELYFLQNATGAVLSPFD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 258 AWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVIDN 337
Cdd:pfam01053 233 AWLLLRGLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGLEAAKKFLDN 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1660651604 338 TKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:pfam01053 313 LKLFSLAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQALE 376
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
16-401 |
7.08e-172 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 486.84 E-value: 7.08e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 16 EYQLDTLAIRTGHTRsfeGEHGE----PIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERA 91
Cdd:COG2873 5 KYGFETLALHAGQEP---DPTTGaravPIYQTTSYVFDDAEHAADLFALKEPGNIYTRIMNPTTDVLEKRIAALEGGVAA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 92 VATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPL 171
Cdd:COG2873 82 LATASGQAAITLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 172 AEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV--GN---------HQLLE 240
Cdd:COG2873 162 LDVLDIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVdgGNfdwaangkfPELTE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 241 -----------EVF-----------SVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYG 298
Cdd:COG2873 242 pdpsyhglvytEAFgnaafitkarvQLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 299 GLPTHEGHELAAKQ-QNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQE 377
Cdd:COG2873 322 GLPSHPYHELAQKYlPKGAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGVTP 401
|
410 420
....*....|....*....|....
gi 1660651604 378 GLIRVSVGLEDINDIIGDISRGLD 401
Cdd:COG2873 402 DLIRLSVGIEDIDDIIADLDQALA 425
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
39-401 |
3.41e-171 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 482.86 E-value: 3.41e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICS 118
Cdd:cd00614 6 PIYQTSTFVFPSPAEAADLFALREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLALLKAGDHVVAS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 119 RAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 198
Cdd:cd00614 86 DDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVVDNTFA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 199 TPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGN-HQLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCE 277
Cdd:cd00614 166 TPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSgEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRMERHSE 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 278 NAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHP 357
Cdd:cd00614 246 NALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGLEAAKKFLNALKLFSLAVSLGGVESLVEHP 325
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1660651604 358 ATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:cd00614 326 ASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
17-401 |
1.99e-154 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 441.50 E-value: 1.99e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 17 YQLDTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSS 96
Cdd:PRK07504 9 WRPATRLVHSGTLRSQFGETSEALFLTQGFVYDTAEAAEARFKGEDPGFIYSRYSNPTVDMFEKRMCALEGAEDARATAS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 97 GMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIAD 176
Cdd:PRK07504 89 GMAAVTAAILCQVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVID 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 177 IQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEE-VFSVVRTLGPSMSP 255
Cdd:PRK07504 169 IAAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGRCLGGVVLSDKAWIEEhLQDYFRHTGPSLSP 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 256 FNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVI 335
Cdd:PRK07504 249 FNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGRADHPQADIIAKQMTGGSTLVAFELKGGKEAAFRFL 328
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1660651604 336 DNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK07504 329 NALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALK 394
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
20-400 |
2.98e-151 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 433.78 E-value: 2.98e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 20 DTLAIRTGHTRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 99
Cdd:PRK07810 17 ATIGVRGGLLRSGFEETAEALYLTSGYVYESAAAAEAAFTGELDRFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 100 AILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQA 179
Cdd:PRK07810 97 AVFTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 180 LADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEE-VFSVVRTLGPSMSPFNA 258
Cdd:PRK07810 177 VSELAHAAGAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGpVQKLMRHTGPALSAFNA 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 259 WIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGE----REGAWKV 334
Cdd:PRK07810 257 WVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPedaaKKRAFEV 336
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1660651604 335 IDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK07810 337 LDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
19-400 |
4.06e-144 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 415.99 E-value: 4.06e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 19 LDTLAIRTGHT-RSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSG 97
Cdd:TIGR01326 2 FETLQLHAGQEpDPTTGSRAVPIYQTTSYVFDSTEHAAALFGLQEPGNIYSRLMNPTTDVLEQRIAALEGGVAALAVASG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 98 MGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADI 177
Cdd:TIGR01326 82 QAAITYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVLDI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 178 QALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV--GN------------------HQ 237
Cdd:TIGR01326 162 EAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVdgGKfdwnngrfplfttpdpsyHG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 238 L-LEEVF-----------SVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEG 305
Cdd:TIGR01326 242 LvFTETLgnpafilkarvQLLRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASHPH 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 306 HELAAK-QQNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSV 384
Cdd:TIGR01326 322 HALAKKyLPKGFGAVLSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLIRLSV 401
|
410
....*....|....*.
gi 1660651604 385 GLEDINDIIGDISRGL 400
Cdd:TIGR01326 402 GIENIDDIIADLEQAL 417
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
21-403 |
2.21e-138 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 400.74 E-value: 2.21e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 21 TLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 99
Cdd:PRK06234 11 TKAIHGGHIGDKQfGSLATPIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 100 AILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQA 179
Cdd:PRK06234 91 AISSSLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTDIKA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 180 LADIAHAN--GALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEV--FSVVRTLGPSMSP 255
Cdd:PRK06234 171 ISNIAHENnkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVklFGIKDMTGSVIGP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 256 FNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVI 335
Cdd:PRK06234 251 FEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKGGVEEGKVVM 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1660651604 336 DNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLDLI 403
Cdd:PRK06234 331 NNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALDLI 398
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
21-401 |
4.75e-134 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 389.63 E-value: 4.75e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 21 TLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 99
Cdd:TIGR01328 6 TRAIHAGYPPKDQfGALTPPIYQTSTFVFDSCEQGGNRFAGQESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATSSGMG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 100 AILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQA 179
Cdd:TIGR01328 86 AIAATLLTILKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLIDMER 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 180 LADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEV--FSVVRTLGPSMSPFN 257
Cdd:TIGR01328 166 VCRDAHSQGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQIrmVGIKDMTGSVISPFD 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 258 AWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVIDN 337
Cdd:TIGR01328 246 AWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAGAKKLLNN 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1660651604 338 TKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:TIGR01328 326 LKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALD 389
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
16-403 |
2.72e-127 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 372.25 E-value: 2.72e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 16 EYQLDTLAIRTGHTrsfEGEH----GEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERA 91
Cdd:PRK06767 3 KKHMETALIHHGYT---SEEHkgslTPPLFQTSTFTFETAQQGEASFAGVDPSYIYSRLGNPTVKLFEERMAVLEGGEEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 92 VATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPL 171
Cdd:PRK06767 80 LAFGSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 172 AEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSVVRT-LG 250
Cdd:PRK06767 160 MKLIDLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKdIG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 251 PSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYgglpthEGHELAAKQQNGFGGIVSFVVKGEREG 330
Cdd:PRK06767 240 GIMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY------PEGELASRQMKRGGGVISFSIKGGKEE 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1660651604 331 AWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLDLI 403
Cdd:PRK06767 314 TQAFINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
21-401 |
1.89e-126 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 370.67 E-value: 1.89e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 21 TLAIRTGHT-RSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 99
Cdd:PRK07503 12 TRAIHHGYDpLDHGGALVPPVYLTATFAFPTAEYGAECFAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALASGMG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 100 AILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQA 179
Cdd:PRK07503 92 AITATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 180 LADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEV--FSVVRTLGPSMSPFN 257
Cdd:PRK07503 172 VAEIAHGAGAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRIrlEGLKDMTGAVMSPFD 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 258 AWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVIDN 337
Cdd:PRK07503 252 AFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKGGIAAGRRFMNA 331
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1660651604 338 TKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK07503 332 LQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALD 395
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
8-401 |
6.49e-126 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 368.59 E-value: 6.49e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 8 LMNQSDDLEYQ-LDTLAIRTGHT-RSFEGEHGEPIFLTSSFVYENAAeaaakfsGQVQGNIYSRFTNPTVSMFEKRLAAL 85
Cdd:PRK07811 1 SEDMSDHHANQgFATRAIHAGYEpDPATGAVNPPIYASSTFAQDGVG-------GLRGGYEYARTGNPTRTALEEQLAAL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 86 DGAERAVATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVE 165
Cdd:PRK07811 74 EGGAYGRAFSSGMAATDCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 166 SPSNPLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSV 245
Cdd:PRK07811 154 TPTNPLLSITDIAALAELAHDAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAF 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 246 VR-TLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVV 324
Cdd:PRK07811 234 LQnGAGAVPGPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 325 KGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGklsveakEAAGIQ----EGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK07811 314 AGGEEAARDFCARTKVFTLAESLGGVESLIEHPSAMTHA-------STAGSQlevpDDLVRLSVGIEDVADLLADLEQAL 386
|
.
gi 1660651604 401 D 401
Cdd:PRK07811 387 G 387
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
39-401 |
1.59e-122 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 360.60 E-value: 1.59e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICS 118
Cdd:PRK08249 30 PVVLSVAYGYDDIDEWYDVALGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFSTGMAAISNTLYTFLKPGDRVVSI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 119 RAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 198
Cdd:PRK08249 110 KDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVDIERLAAAAKKVGALVVVDNTFA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 199 TPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCEN 278
Cdd:PRK08249 190 TPINQNPLALGADLVIHSATKFLSGHADALGGVVCGSKELMEQVYHYREINGATMDPMSAYLILRGMKTLKLRVRQQQES 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 279 AQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPA 358
Cdd:PRK08249 270 AMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKGGMDTVKRLLPKLRYAHRAANLGAVETIYGPAR 349
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1660651604 359 TTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK08249 350 TTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFA 392
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
20-400 |
1.59e-119 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 354.04 E-value: 1.59e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 20 DTLAIRTG-HTRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGM 98
Cdd:PRK08134 10 DTLALHAGaAPDPATGARAVPIHLTTSFVFRDSDHAAALFNLERAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 99 GAI-LSIAmAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADI 177
Cdd:PRK08134 90 AALhLAIA-TLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 178 QALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV---------------------GNH 236
Cdd:PRK08134 169 PTVAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVdggrfdweasgkfpeltepyaGFH 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 237 QL-LEEVFSV-----------VRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHE 304
Cdd:PRK08134 249 GMvFAEESTVaafllrarregLRDFGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESHP 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 305 GHELAAK-QQNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVS 383
Cdd:PRK08134 329 DHALAKRlLPRGAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRLS 408
|
410
....*....|....*..
gi 1660651604 384 VGLEDINDIIGDISRGL 400
Cdd:PRK08134 409 IGLEDADDLIDDLKRAL 425
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
39-400 |
3.29e-119 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 353.29 E-value: 3.29e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGA----ILSIAmaylKAGDH 114
Cdd:PRK07812 35 PIYQTTSYTFDDTDHAAALFGLAEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASGQAAetfaILNLA----GAGDH 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 115 VICSRAVFGSIVALFEKYIAKFGVDITFV-DLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAV 193
Cdd:PRK07812 111 IVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQIDVLDIPGVAEVAHEAGVPLIV 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 194 DNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV---------GNHQLLEE--------VFS------------ 244
Cdd:PRK07812 191 DNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdggtfdwtqGRFPGFTTpdpsyhgvVFAelgppayalkar 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 245 --VVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAK-QQNGFGGIVS 321
Cdd:PRK07812 271 vqLLRDLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSPWYERAKRlAPKGTGAVLS 350
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1660651604 322 FVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK07812 351 FELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAVGIEGIDDILADLEAGF 429
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
12-400 |
1.68e-114 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 341.05 E-value: 1.68e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 12 SDDLEYQLDTLAIRTGHT-RSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAER 90
Cdd:PRK08248 2 SEERTFRLETLAIHAGQEiDPTTGSRAVPIYQTTSYGFRDSEHAANLFSLKEFGNIYTRIMNPTTDVFEKRIAALEGGIG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 91 AVATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNP 170
Cdd:PRK08248 82 ALAVSSGQAAITYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 171 LAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV----------GNHQLLE 240
Cdd:PRK08248 162 KGDVLDIEAVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVdsgkfdwkgsGKFPGLT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 241 EV-----------------------FSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYY 297
Cdd:PRK08248 242 EPdpsyhglvytdavgeaayitkarVQLLRDLGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 298 GGLPTHEGHELAAKQ-QNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQ 376
Cdd:PRK08248 322 PGLPSHPSYELAKKYlPKGQGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVT 401
|
410 420
....*....|....*....|....
gi 1660651604 377 EGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK08248 402 PGLVRLSVGTEAIDDILDDLRQAI 425
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
39-401 |
6.11e-112 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 332.84 E-value: 6.11e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFVYENAaeaaakfsGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMaYLKAGDHVICS 118
Cdd:PRK07671 24 PIYQVSTYKQEAV--------GKHQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAITAVMM-LFSSGDHVILT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 119 RAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 198
Cdd:PRK07671 95 DDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTIAKEKGLLTIVDNTFM 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 199 TPVLQQPLKLGADLVIYSATKYLDGQGRALGG-AVVGNHQLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCE 277
Cdd:PRK07671 175 TPYWQSPISLGADIVLHSATKYLGGHSDVVAGlVVVNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLKTLGIRMEEHET 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 278 NAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVkGEREGAWKVIDNTKFISITGNLGDVKSTITHP 357
Cdd:PRK07671 255 NSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDV-GSEETANKVLERLQYFTLAESLGAVESLISIP 333
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 1660651604 358 ATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK07671 334 SQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
19-403 |
9.51e-111 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 331.29 E-value: 9.51e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 19 LDTLAIRTG-HTRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSG 97
Cdd:PRK05994 8 FATLAVHAGaQPDPTTGARATPIYQTTSFVFNDADHAASLFGLQAFGNIYTRITNPTNAVLEERVAALEGGTAALAVASG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 98 MGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADI 177
Cdd:PRK05994 88 HAAQFLVFHTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTDI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 178 QALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV----------GNHQLLEE------ 241
Cdd:PRK05994 168 AAIAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIVdggtfdwsksGKYPMLSEprpeyh 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 242 -----------VFSV------VRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHE 304
Cdd:PRK05994 248 glvlhetfgnfAFAIaarvlgLRDLGPAISPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPDDP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 305 GHELAAK-QQNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVS 383
Cdd:PRK05994 328 YHALAQKySPKGAGAVFTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVRLS 407
|
410 420
....*....|....*....|
gi 1660651604 384 VGLEDINDIIGDISRGLDLI 403
Cdd:PRK05994 408 IGIEDVDDIIADLEQALAKA 427
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
10-403 |
6.12e-105 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 316.81 E-value: 6.12e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 10 NQSDDLEYQLDTLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGA 88
Cdd:PRK05613 5 DNSNADQWGFETRSIHAGQSVDSDtSARNLPIYQTTSYVFDSAEHAKQRFALEDLGPIYSRLTNPTVEALENRIASLEGG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 89 ERAVATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFV-DLSDLNAWKNAVRPETKLLFVESP 167
Cdd:PRK05613 85 VHAVAFASGQAAETAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETF 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 168 SNPLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV--GNHQLLEE---- 241
Cdd:PRK05613 165 ANPQADVLDIPAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIdgGKFDWTVErdgk 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 242 -VF-----------------------------SVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEK 291
Cdd:PRK05613 245 pVFpyfvtpdpayhglkyadlgapafglkaraGLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEK 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 292 VEKVYYGGLPTHEGHelAAKQQNGF---GGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVE 368
Cdd:PRK05613 325 VAKVNFAGLKDSPWY--ATKEKLGLkytGSVLSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEA 402
|
410 420 430
....*....|....*....|....*....|....*
gi 1660651604 369 AKEAAGIQEGLIRVSVGLEDINDIIGDISRGLDLI 403
Cdd:PRK05613 403 GLARAGITQATVRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
21-400 |
4.79e-102 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 307.76 E-value: 4.79e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 21 TLAIRtGHTRSFE-GEHGEPIFLTSsfVYENAAEAAAKFSGQVQGniYSRFTNPTVSMFEKRLAALDGAERAVATSSGMG 99
Cdd:PRK08574 5 TDAVR-GYRGSDPyGSLQPPIYLTA--LFRQEGEAYPSDRGFDLK--YSREENPTLRPLEEALAKLEGGVDALAFNSGMA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 100 AILSIAMAYLKAGDHVICSRAVFGSIVALFEKyIAKFGVDI--TFVDLSDLNAWKNAVRPetKLLFVESPSNPLAEIADI 177
Cdd:PRK08574 80 AISTLFFSLLKAGDRVVLPMEAYGTTLRLLKS-LEKFGVKVvlAYPSTEDIIEAIKEGRT--KLVFIETMTNPTLKVIDV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 178 QALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGG-AVVGNHQLLEEVFSVVRTLGPSMSPF 256
Cdd:PRK08574 157 PEVAKAAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGvAVAWSGEFLEELWEWRRRLGTIMQPF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 257 NAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAK--QQNGFGGIVSFVVKGEREGAWKV 334
Cdd:PRK08574 237 EAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGVAKRlfGKDLYGGVVSFRVKGGRDAVLKF 316
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1660651604 335 IDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK08574 317 LRSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQAL 382
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
16-403 |
1.61e-100 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 304.00 E-value: 1.61e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 16 EYQLDTLAIRTGH-TRSFEGEHGEPIFLTSSFvYENAAEAAAKFSgqvqgniYSRFTNPTVSMFEKRLAALDGAERAVAT 94
Cdd:PRK08064 4 SYSIDTLLLHNQYkHDKQTGAVNVPIYHASTF-HQFDFDTFGKYD-------YSRSGNPTREALEDIIAELEGGTKGFAF 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 95 SSGMGAIlSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEI 174
Cdd:PRK08064 76 ASGMAAI-STAFLLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 175 ADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGG-AVVGNHQLLEEVFSVVRTLGPSM 253
Cdd:PRK08064 155 TDIRGVVKLAKAIGCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGlAVVKDEELAQKLYFLQNSFGAVL 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 254 SPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGErEGAWK 333
Cdd:PRK08064 235 GVQDCWLVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSE-EAVRQ 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 334 VIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLDLI 403
Cdd:PRK08064 314 FVSHVKLPVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYV 383
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
39-400 |
5.58e-100 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 302.14 E-value: 5.58e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFVYEnaaeAAAKFSgqvqgniYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICS 118
Cdd:PRK06460 22 PIYQTTAYHYP----EGEKYR-------YSREANPTVLELTKKIVELENAEMGVAFSSGMGAISTTALALLKPGNSVLVH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 119 RAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 198
Cdd:PRK06460 91 RDMFGRSYRFFTDYLKNWGVNVDASNPGSDNIIEKAKSKRYDVVFVENITNPLLRVVDITELSKVCKENGSILIVDATFS 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 199 TPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCEN 278
Cdd:PRK06460 171 TPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGKLLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDVINRN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 279 AQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPA 358
Cdd:PRK06460 251 AEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNGGQESALKVMKSLKLIIPAQTLGGVNSVISHPA 330
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1660651604 359 TTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK06460 331 TMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRAL 372
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
16-400 |
7.16e-100 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 301.62 E-value: 7.16e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 16 EYQLDTLAIRTGHtRSFE--GEHGEPIFLTSSFVYENAAEAAakfsgqvqGNIYSRFTNPTVSMFEKRLAALDGAERAVA 93
Cdd:PRK08247 2 MSTIETKLAQIGN-RSDErtGTVNPPVYFSTAYRHEGIGEST--------GFDYSRTGNPTRGVLEQAIADLEGGDQGFA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 94 TSSGMGAILSIaMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAE 173
Cdd:PRK08247 73 CSSGMAAIQLV-MSLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQ 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 174 IADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQ-LLEEVFSVVRTLGPS 252
Cdd:PRK08247 152 ETDIAAIAKIAKKHGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQeLCERLAYYQNAAGAV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 253 MSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLptheghelaakqqngfGGIVSFVVKGEregAW 332
Cdd:PRK08247 232 LSPFDSWLLIRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLYPGR----------------GGMLSFRLQDE---EW 292
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 333 --KVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK08247 293 vnPFLKSLKLITFAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAF 362
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
18-401 |
7.30e-100 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 303.36 E-value: 7.30e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 18 QLDTLAIRTGHTRSFEGEH-GEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSS 96
Cdd:PRK06084 2 KLETLAIHAGYSPDPTTKAvAVPIYQTTSYAFDDTQHGADLFDLKVPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 97 GMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIAD 176
Cdd:PRK06084 82 GMAAITYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNIID 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 177 IQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV-------GNHQLLEEVFSV---- 245
Cdd:PRK06084 162 IQALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVdsgkfpwAEHKERFALLNTpdps 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 246 -----------------------VRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPT 302
Cdd:PRK06084 242 yhgvtyteafgpaafigrcrvvpLRNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLPD 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 303 HEGHELAAKQQNGF-GGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIR 381
Cdd:PRK06084 322 HPEHELARRYMGGKpASILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMVR 401
|
410 420
....*....|....*....|
gi 1660651604 382 VSVGLEDINDIIGDISRGLD 401
Cdd:PRK06084 402 LSIGIEHIDDIIADLAQALD 421
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
39-400 |
5.05e-99 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 299.89 E-value: 5.05e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFvYENAAeaaakfsGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIaMAYLKAGDHVICS 118
Cdd:PRK06176 24 PIYQTSTY-RQDAI-------GRPKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAV-FSLFQSGDHVLLG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 119 RAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 198
Cdd:PRK06176 95 DDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 199 TPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNH-QLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCE 277
Cdd:PRK06176 175 TPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNeALAQEIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAHQK 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 278 NAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREgAWKVIDNTKFISITGNLGDVKSTITHP 357
Cdd:PRK06176 255 NALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSE-AVAFVESLKLFILGESLGGVESLVGIP 333
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1660651604 358 ATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK06176 334 AFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAF 376
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
39-400 |
4.39e-97 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 297.71 E-value: 4.39e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFVYENAAEaaakfSGQVQgniYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAiLSIAMAYLKAGDHVICS 118
Cdd:PLN02509 107 PLYQTATFKQPSAIE-----NGPYD---YTRSGNPTRDALESLLAKLDKADRAFCFTSGMAA-LSAVTHLIKNGEEIVAG 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 119 RAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 198
Cdd:PLN02509 178 DDVYGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLVDNSIM 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 199 TPVLQQPLKLGADLVIYSATKYLDGQGRALGGAV-VGNHQLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCE 277
Cdd:PLN02509 258 SPVLSRPLELGADIVMHSATKFIAGHSDVMAGVLaVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQE 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 278 NAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVkGEREGAWKVIDNTKFISITGNLGDVKSTITHP 357
Cdd:PLN02509 338 NARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFIT-GSVALSKHLVETTKYFSIAVSFGSVKSLISMP 416
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 1660651604 358 ATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PLN02509 417 CFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAF 459
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
21-400 |
6.71e-97 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 295.36 E-value: 6.71e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 21 TLAIRTGHTRsfEGEHGE---PIFLTSSFVYEnaaeaaaKFSGQVQGNiYSRFTNPTVSMFEKRLAALDGAERAVATSSG 97
Cdd:PRK08776 15 TAAVRAGIDR--DTAYGAvtpPIVLSSNFSFD-------GFGNKRQYD-YTRSGNPTRDLLGEALAELEGGAGGVITATG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 98 MGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADI 177
Cdd:PRK08776 85 MGAINLVLNALLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 178 QALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVG-NHQLLEEVFSVVRTLGPSMSPF 256
Cdd:PRK08776 165 RFVIEAAHKVGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVArDAELHQQLVWWANALGLTGSPF 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 257 NAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKVID 336
Cdd:PRK08776 245 DAFLTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAVRAFVD 324
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1660651604 337 NTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK08776 325 GLRYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGL 388
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
19-400 |
4.10e-96 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 292.12 E-value: 4.10e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 19 LDTLAIRTGHTRSFEGEHGEPIFLTSSFVyENAAEAAAKFSgqvqgniYSRFTNPTVSMFEKRLAALDGAERAVATSSGM 98
Cdd:TIGR01329 1 LSTLLVNTDNKNDPYDASSMPIYQTATFK-QPLAIENGPYD-------YTRSGNPTRTALESLLAKLDKADRAFAFSSGM 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 99 GAiLSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQ 178
Cdd:TIGR01329 73 AA-LDVITRLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 179 ALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAV-VGNHQLLEEVFSVVRTLGPSMSPFN 257
Cdd:TIGR01329 152 KISEMAHAQNALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLaVKGEEIAKKVYFLQNSTGSGLAPFD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 258 AWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVkGEREGAWKVIDN 337
Cdd:TIGR01329 232 CWLLLRGIKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFET-GSVALSKRLVEA 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1660651604 338 TKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:TIGR01329 311 TKLFSITVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
33-401 |
7.79e-92 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 283.10 E-value: 7.79e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 33 EGEHGEPIFLTSSFVYENAAEAAAKF----------SGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAIL 102
Cdd:PRK07049 33 EGAVKPPVFLTSTFVFRSAEDGRDFFdyvsgrkeppAGEGAGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 103 SIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVD-ITFVDLSDLNAWKNAV-----RPETKLLFVESPSNPLAEIAD 176
Cdd:PRK07049 113 TTLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAeaaaaKGRVSLILIETPANPTNSLVD 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 177 IQALADIAHANGA------LLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSVVRTLG 250
Cdd:PRK07049 193 VAAVRRVADAIEArqghrpIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAVLGRKALIRQVRALRSAIG 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 251 PSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYggLPTHEGHELAAK----QQNGFGGIVSFVVKG 326
Cdd:PRK07049 273 TQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHY--LPFLDPDSAYGAvykrQCTGAGSTFSFDIKG 350
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1660651604 327 EREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK07049 351 GQAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPDDLIADLAQALD 425
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
21-400 |
1.49e-91 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 281.01 E-value: 1.49e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 21 TLAIRTGHTRsfEGEHG---EPIFLTSSFvyenaaeaaaKFSG--QVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATS 95
Cdd:PRK08045 7 TIAVRSGLND--DEQYGcvvPPIHLSSTY----------NFTGfnEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 96 SGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIA 175
Cdd:PRK08045 75 TGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 176 DIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVG-NHQLLEEVFSVVRTLGPSMS 254
Cdd:PRK08045 155 DIAKICHLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAkDPDVVTELAWWANNIGVTGG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 255 PFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWKV 334
Cdd:PRK08045 235 AFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRF 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1660651604 335 IDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK08045 315 LGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGF 380
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
35-403 |
3.85e-91 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 280.04 E-value: 3.85e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 35 EHG---EPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYLKA 111
Cdd:PRK05939 6 EHGavhKPIHTSVTYGYEDARDLIDVFQGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLTLLRA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 112 GDHVICSRAVFGSIVALFEKyIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALL 191
Cdd:PRK05939 86 GDHLVSSQFLFGNTNSLFGT-LRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLY 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 192 AVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV--------GNHQLLEEVFSV--------------VRTL 249
Cdd:PRK05939 165 VVDNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdtglfdwsAYPNIFPAYRKGdpqqwgltqirkkgLRDM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 250 GPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKgERE 329
Cdd:PRK05939 245 GATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELA-DGI 323
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1660651604 330 GAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLDLI 403
Cdd:PRK05939 324 DCFDFLNRLKLVIKATHLGDTRTLVIPVAPTIYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
16-398 |
2.75e-88 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 272.54 E-value: 2.75e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 16 EYQLDTLAIRTG-HTRSFEGEHGEPIFLTSSFVYenaaeaaAKFsGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVAT 94
Cdd:PRK08861 3 TRKPATIAVRTGiESDSQYHAVVPPIYLSTNYGF-------PAF-GEVPKYDYTRSGNPNRGLLEQTLSELESGKGAVVT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 95 SSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEI 174
Cdd:PRK08861 75 NCGTSALNLWVSALLGPDDLIVAPHDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 175 ADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNH-QLLEEVFSVVRTLGPSM 253
Cdd:PRK08861 155 VDIAELCQKAKAVGALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTkEHAEELAWWGNCIGATG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 254 SPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREGAWK 333
Cdd:PRK08861 235 TPFDSYMTLRGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSFEQLKV 314
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1660651604 334 VIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISR 398
Cdd:PRK08861 315 FVKALALFSLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQ 379
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
19-401 |
2.54e-86 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 267.54 E-value: 2.54e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 19 LDTLAIRTGHTRSFE-GEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSG 97
Cdd:PRK06434 9 FNTRAVQSGELRDPRfGNVTTPIFETSTFVYPNSEKEAYMDSTRGMPYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 98 MGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKnaVRPET-KLLFVESPSNPLAEIAD 176
Cdd:PRK06434 89 MGAITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSLD--FDPSNyDLIYAESITNPTLKVPD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 177 IQALADIAHANgaLLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAV-VGNHQLLEEVFSVVRTLGPSMSP 255
Cdd:PRK06434 167 IKNVSSFCHEN--DVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAgTNNKSIFNNLVERRKTLGSNPDP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 256 FNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLptheghELAAKQQNGFGGIVSFVVKGEREgAWKVI 335
Cdd:PRK06434 245 IQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDT------EIGKKVLRGFGGMLSFELRSMED-VHKFI 317
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1660651604 336 DNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK06434 318 RNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALS 383
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
9-400 |
4.00e-86 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 266.95 E-value: 4.00e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 9 MNQSDDLeyqLDTLAIRTGHTRSFEGEHG-EPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDG 87
Cdd:PRK05968 1 MNDGLDP---FDLAALITAHDEGNAFDAVvPPIFQTSLFTFDSYDEMEDVYAGEKVRPIYSRGDNPTVRAFEEMLAKLEG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 88 AERAVATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVrPETKLLFVESP 167
Cdd:PRK05968 78 AEDARGFASGMAAISSTVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLESP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 168 SNPLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLL----EEVF 243
Cdd:PRK05968 157 TSWVFELQDVAALAALAKRHGVVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIarinAEAY 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 244 SVvrtLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELaakqqNGFGGIVSFV 323
Cdd:PRK05968 237 PY---LGAKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPPAGL-----SGTSGLFSFI 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 324 VKGEREGAwKVIDNTKFISITGNLGDVKSTIThPATTThgkLSVEAK----EAAGIQEGLIRVSVGLEDINDIIGDISRG 399
Cdd:PRK05968 309 FREGIDVR-AFADALKLFRLGVSWGGHESLVV-PAEVV---LQQKAQpnsaARFGVSPRSVRLHVGLEGTEALWADLEQA 383
|
.
gi 1660651604 400 L 400
Cdd:PRK05968 384 L 384
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
21-400 |
5.06e-78 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 247.66 E-value: 5.06e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 21 TLAIRTGHTRSFEGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGA 100
Cdd:PRK06702 9 TICVQGGYTPKNGEPRVLPLYQSTTYKYDTSDDLAALFNLEAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASGQAA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 101 ILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVD----LSDLNAWKNavrPETKLLFVESPSNPLAEIAD 176
Cdd:PRK06702 89 IMLAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNpnltADEIVALAN---DKTKLVYAESLGNPAMNVLN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 177 IQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVV--GNHQ----------------- 237
Cdd:PRK06702 166 FKEFSDAAKELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdgGNFDwtngkypelvepdpsyh 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 238 -------------LLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHE 304
Cdd:PRK06702 246 gvsyvqnfgaaayIVKARVQLLRDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 305 GHELAAKQ-QNGFGGIVSFVVKGEREGAWKVIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVS 383
Cdd:PRK06702 326 NYSLAQKYlKKGASGVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIRLS 405
|
410
....*....|....*..
gi 1660651604 384 VGLEDINDIIGDISRGL 400
Cdd:PRK06702 406 VGIEDVSDIIADLEAAL 422
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
25-401 |
3.80e-76 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 240.67 E-value: 3.80e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 25 RTGHTRSFEGEHGEPIFLTSSFvyenaaeaAAKF---SGQVQG-NIYSRFTNPTVSMFEKRLAALDGAErAVATSSGMGA 100
Cdd:PRK07582 7 RSVHAGGPEAVPGEPVLPGPVF--------AAPYhlsPGEPTGpDTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 101 ILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAwknAVRPETKLLFVESPSNPLAEIADIQAL 180
Cdd:PRK07582 78 ITAVLRALLRPGDTVVVPADGYYQVRALAREYLAPLGVTVREAPTAGMAE---AALAGADLVLAETPSNPGLDVCDLAAL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 181 ADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNH-QLLEEVFSVVRTLGPSMSPFNAW 259
Cdd:PRK07582 155 AAAAHAAGALLVVDNTTATPLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDpELMAAVERWRLLAGAIPGPFEAW 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 260 IFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVkGEREGAWKVIDNTK 339
Cdd:PRK07582 235 LAHRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGDPAHEVAARQMRRFGGLVSFEL-ADAAAAERFVAASR 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1660651604 340 FISITGNLGDVKSTITHpattthgklsvEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK07582 314 LVVAATSFGGVHTSADR-----------RARWGDAVPEGFVRLSCGIEDTDDLVADLERALD 364
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
34-385 |
1.04e-75 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 241.21 E-value: 1.04e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 34 GEHG---EPIFLTSSFVYENAAEAAAKFSGQVQGN----IYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAM 106
Cdd:PLN02242 30 GEHGgvnMSIEASATFTVMEPDTMRRMFSGELGPDrdfyIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAISSVLL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 107 AYLKAGDHVICSRAVFGSIVALFEKYIA-KFGVDITFVDLSDLNAWKNAVRP-ETKLLFVESPSNPLAEIADIQALADIA 184
Cdd:PLN02242 110 QLCSSGGHVVASNTLYGGTHALLAHFLPrKCNITTTFVDITDLEAVKKAVVPgKTKVLYFESISNPTLTVADIPELARIA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 185 HANGALLAVDNSFcTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSV----VRTLGPSMSPFNAWI 260
Cdd:PLN02242 190 HEKGVTVVVDNTF-APMVLSPARLGADVVVHSISKFISGGADIIAGAVCGPAELVNSMMDLhhgaLMLLGPTMNPKVAFE 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 261 FLKGLETLRLRMKAHCENAQKLAEWLSthEKVEKVYYGGLPTHEGHELAAKQQN---GFGGIVSFVVKGErEGAWKVIDN 337
Cdd:PLN02242 269 LSERLPHLSLRMKEHCRRAMEYAKRMK--ELGLKVIYPGLEDHPQHALLKSMANkgyGFGGLLCLDMDTE-ERANRLMRY 345
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 1660651604 338 ----TKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVG 385
Cdd:PLN02242 346 lqnsTQFGFMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVG 397
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
16-401 |
8.17e-73 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 232.02 E-value: 8.17e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 16 EYQLDTLAIRTG-HTRSFEGEHGEPIFLTSSFVYenaaeaaAKFsGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVAT 94
Cdd:PRK07269 4 DLHINTILAQAGiKSDEATGALVTPLHFSTTYQH-------PEF-GQSTGFDYTRTKNPTRAKLEETLAAIESADYALAT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 95 SSGMGAILsIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDlnAWKNAVRPETKLLFVESPSNPLAEI 174
Cdd:PRK07269 76 SSGMSAIV-LAFSVFPVGSKVVAVRDLYGGSFRWFNQQEKEGRFHFTYANTEE--ELIAAIEEDTDIVYIETPTNPLMVE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 175 ADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQ-LLEEVFSVVRTLGPSM 253
Cdd:PRK07269 153 FDIEKVAKLAHAKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLeLYEKLFYNLNTTGAVL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 254 SPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLptheghelaakqqngfGGIVSFVVKGEREGAwK 333
Cdd:PRK07269 233 SPFDSYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYTGK----------------GGMISFKVADETRIP-H 295
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1660651604 334 VIDNTKFISITGNLGDVKSTITHPATTTHGKLSVEAKEAAGIQEGLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK07269 296 ILNSLKVFTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQALE 363
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
30-400 |
5.87e-58 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 194.26 E-value: 5.87e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 30 RSFEGEHGEPIFLTSSFVYENAAEAAAKfsgqVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYL 109
Cdd:PRK05967 25 GDYHGFVNPPVVHASTVLFPDAETMATR----GQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTVPFLGFL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 110 KAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGA 189
Cdd:PRK05967 101 SPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAEAAHRHGA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 190 LLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLR 269
Cdd:PRK05967 181 IVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEKCWPQLLEAHGTLGLCAGPDDTYQILRGLRTMG 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 270 LRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGEREG----AWKVIDNTKFISITG 345
Cdd:PRK05967 261 IRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPEKgkakAHAFLDALEIFGLGY 340
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 1660651604 346 NLGDVKStithpaTTTHGKLSvEAKEAAGIQEG-LIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK05967 341 SWGGYES------LALHVKLG-DRTVAKAPYAGpVIRLQIGLEDVPDLKADLERGF 389
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
18-401 |
1.39e-51 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 177.62 E-value: 1.39e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 18 QLDTLAIRTGHTRSF-EGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNI-YSRFTNPTVSMFEKRLAALDGAERAVATS 95
Cdd:PRK09028 4 KKATKIVSAGRDKKWtKGVINPPVFRASTVVFDTVAEMRHAAKNRANGEMfYGRRGTPTHFAFQAAIVELEGGAGTALYP 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 96 SGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVD------LSDLnawknaVRPETKLLFVESPSN 169
Cdd:PRK09028 84 SGAAAISNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDpmigegIREL------IRPNTKVLFLESPGS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 170 PLAEIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGNHQLLEEVFSVVRTL 249
Cdd:PRK09028 158 ITMEVQDVPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGTATANEKHWDQLREHSYLM 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 250 GPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVK-GER 328
Cdd:PRK09028 238 GQCTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqGDP 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1660651604 329 EGAWKVIDNTKFISITGNLGDVKSTIThpATTTHGKL-SVEAKEAAGIqegLIRVSVGLEDINDIIGDISRGLD 401
Cdd:PRK09028 318 KAVTALVEGMQHFKMGFSWGGFESLIL--GVFGINKLrTATNWDFSKP---LIRLHIGLEDVDDLIADLEAGFE 386
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
39-400 |
4.05e-51 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 176.07 E-value: 4.05e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 39 PIFLTSSFVYENAAEAAAKFSGQVQGNIYSRFTNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICS 118
Cdd:PRK07050 31 PVARASTVVFPDLATMRALDWRQDVQWRYGLHATPTSLALAQRLAEIEGGRHALLQPSGLAAISLVYFGLVKAGDDVLIP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 119 RAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFC 198
Cdd:PRK07050 111 DNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEVPDVPAITAAARARGVVTAIDNTYS 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 199 TPVLQQPLKLGADLVIYSATKYLDGQGRALGGAV-VGNHQLLEEVFSVVRTLGPSMSPFNAWIFLKGLETLRLRMKAHCE 277
Cdd:PRK07050 191 AGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATiTADAELHAKLKLARMRLGIGVSADDCSLVLRGLPSLQVRLAAHDR 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 278 NAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKgEREGAWKV---IDNTKFISITGNLGDVKS-- 352
Cdd:PRK07050 271 SALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFD-ERYSPAQVdafVEALELFAIGWSWGGACSla 349
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1660651604 353 -----TITHPATTTHGKlsveakeaagiqeGLIRVSVGLEDINDIIGDISRGL 400
Cdd:PRK07050 350 mpydvASMRTAKWPHRG-------------TLVRLYIGLEDEADLIADLEQAL 389
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
16-403 |
7.87e-42 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 151.78 E-value: 7.87e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 16 EYQLDTLAIRTGHTRSF-EGEHGEPIFLTSSFVYENAAEAAAKFSGQVQGNI-YSRFTNPTVSMFEKRLAALDGAERAVA 93
Cdd:PRK08114 3 DKKLDTQLVNAGRSKKYtQGSVNSVIQRASSLVFDSVEAKKHATRNRANGELfYGRRGTLTHFSLQEAMCELEGGAGCAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 94 TSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLSDLNAWKNAVRPETKLLFVESPSNPLAE 173
Cdd:PRK08114 83 YPCGAAAVANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSITME 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 174 IADIQALADIAH--ANGALLAVDNSFCTPVLQQPLKLGADLVIYSATKYLDGQGRALGGAVVGN----HQLLEEVFsvvr 247
Cdd:PRK08114 163 VHDVPAIVAAVRsvNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVANarcwEQLRENSY---- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 248 TLGPSMSPFNAWIFLKGLETLRLRMKAHCENAQKLAEWLSTHEKVEKVYYGGLPTHEGHELAAKQQNGFGGIVSFVVKGE 327
Cdd:PRK08114 239 LMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKKK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 328 --REGAWKVIDNTKFISITGNLGDVKSTIthpattthgkLSVEAKEAAGIQEG--------LIRVSVGLEDINDIIGDIS 397
Cdd:PRK08114 319 ltDEQLANYLDNFSLFSMAYSWGGFESLI----------LANQPEEIAAIRPAgevdftgtLIRLHIGLEDVDDLIADLA 388
|
....*.
gi 1660651604 398 RGLDLI 403
Cdd:PRK08114 389 AGFARI 394
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
78-320 |
3.44e-15 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 76.23 E-value: 3.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 78 FEKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFEKY---IAKFGVDITFVDLSDLNAWKNA 154
Cdd:cd00609 49 LGRRGGVDVPPEEIVVTNGAQEALSLLLRALLNPGDEVLVPDPTYPGYEAAARLAgaeVVPVPLDEEGGFLLDLELLEAA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 155 VRPETKLLFVESPSNP---LAEIADIQALADIAHANGALLAVD--------NSFCTPVLQQPLKLGADLVIYSATKYLDG 223
Cdd:cd00609 129 KTPKTKLLYLNNPNNPtgaVLSEEELEELAELAKKHGILIISDeayaelvyDGEPPPALALLDAYERVIVLRSFSKTFGL 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 224 QG-RaLGGAVVGNHQLLEEVFSVVRTLGPSMSPFNAWIFLKGLET----LRLRMKAHCENAQKLAEWLSTHEKVEKVYYG 298
Cdd:cd00609 209 PGlR-IGYLIAPPEELLERLKKLLPYTTSGPSTLSQAAAAAALDDgeehLEELRERYRRRRDALLEALKELGPLVVVKPS 287
|
250 260
....*....|....*....|....*....
gi 1660651604 299 G-------LPTHEGHELAAKQQNGFGGIV 320
Cdd:cd00609 288 GgfflwldLPEGDDEEFLERLLLEAGVVV 316
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
78-235 |
4.70e-11 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 60.86 E-value: 4.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 78 FEKRLAAL--DGAERAVATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALFekyIAKFGVDITFVD--------LSD 147
Cdd:cd01494 5 LEEKLARLlqPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYWVA---AELAGAKPVPVPvddagyggLDV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 148 LNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNSFCtpVLQQPLKL------GADLVIYSATKYL 221
Cdd:cd01494 82 AILEELKAKPNVALIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASA--GGASPAPGvlipegGADVVTFSLHKNL 159
|
170
....*....|....
gi 1660651604 222 DGQGralGGAVVGN 235
Cdd:cd01494 160 GGEG---GGVVIVK 170
|
|
| PLN02855 |
PLN02855 |
Bifunctional selenocysteine lyase/cysteine desulfurase |
80-256 |
7.85e-11 |
|
Bifunctional selenocysteine lyase/cysteine desulfurase
Pssm-ID: 215460 [Multi-domain] Cd Length: 424 Bit Score: 63.23 E-value: 7.85e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 80 KRLAALDGAERA---VATSSGMGAILSIA----MAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLS-----D 147
Cdd:PLN02855 83 KKVAAFINASTSreiVFTRNATEAINLVAytwgLANLKPGDEVILSVAEHHSNIVPWQLVAQKTGAVLKFVGLTpdevlD 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 148 LNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDNsfCTPVLQQPL---KLGADLVIYSATKYLDGQ 224
Cdd:PLN02855 163 VEQLKELLSEKTKLVATHHVSNVLGSILPVEDIVHWAHAVGAKVLVDA--CQSVPHMPVdvqTLGADFLVASSHKMCGPT 240
|
170 180 190
....*....|....*....|....*....|..
gi 1660651604 225 GRalgGAVVGNHQLLEevfsvvrtlgpSMSPF 256
Cdd:PLN02855 241 GI---GFLWGKSDLLE-----------SMPPF 258
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
37-194 |
1.32e-10 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 62.32 E-value: 1.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 37 GEPIFLTSsfvyENAAEAAAKFSGQVQGNIYSRFTNPTVsmFEKRLAAL--------DGAERAVATSSGMGAILSIAMAY 108
Cdd:pfam00155 9 NEYLGDTL----PAVAKAEKDALAGGTRNLYGPTDGHPE--LREALAKFlgrspvlkLDREAAVVFGSGAGANIEALIFL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 109 LK-AGDHVICSRAVFGSIVALFEKYiakfGVDITFVDLS-------DLNAWKNAVRPETKLLFVESPSNP---LAEIADI 177
Cdd:pfam00155 83 LAnPGDAILVPAPTYASYIRIARLA----GGEVVRYPLYdsndfhlDFDALEAALKEKPKVVLHTSPHNPtgtVATLEEL 158
|
170
....*....|....*..
gi 1660651604 178 QALADIAHANGALLAVD 194
Cdd:pfam00155 159 EKLLDLAKEHNILLLVD 175
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
88-195 |
5.35e-10 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 60.53 E-value: 5.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 88 AERAVATSSGMGAILSIAMAYLKAGDHVICSR---AVFGSIVALFekyiakfGVDITFVDLS-------DLNAWKNAVRP 157
Cdd:COG0436 90 PDEILVTNGAKEALALALLALLNPGDEVLVPDpgyPSYRAAVRLA-------GGKPVPVPLDeengflpDPEALEAAITP 162
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1660651604 158 ETKLLFVESPSNP---LAEIADIQALADIAHANGALLAVDN 195
Cdd:COG0436 163 RTKAIVLNSPNNPtgaVYSREELEALAELAREHDLLVISDE 203
|
|
| Aminotran_5 |
pfam00266 |
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes ... |
79-326 |
1.56e-09 |
|
Aminotransferase class-V; This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-.
Pssm-ID: 425567 [Multi-domain] Cd Length: 368 Bit Score: 59.18 E-value: 1.56e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 79 EKRLAALDGAERA---VATSSGMGAILSIAMAY---LKAGDHVICSR----AVFGSIVALfekyiAKF-GVDITFVDLS- 146
Cdd:pfam00266 49 REKVAEFINAPSNdeiIFTSGTTEAINLVALSLgrsLKPGDEIVITEmehhANLVPWQEL-----AKRtGARVRVLPLDe 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 147 ----DLNAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDnsFCTPVLQQPL---KLGADLVIYSATK 219
Cdd:pfam00266 124 dgllDLDELEKLITPKTKLVAITHVSNVTGTIQPVPEIGKLAHQYGALVLVD--AAQAIGHRPIdvqKLGVDFLAFSGHK 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 220 YLdgqGRALGGAVVGNHQLLEE----------VFSVV---RTLGPSMSPFNA-------WIflkGL-ETLRLRMKAHCEN 278
Cdd:pfam00266 202 LY---GPTGIGVLYGRRDLLEKmppllggggmIETVSlqeSTFADAPWKFEAgtpniagII---GLgAALEYLSEIGLEA 275
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 1660651604 279 AQKLAewlstHEKVEKVyYGGLPTHEGHELAAKQQNgfGGIVSFVVKG 326
Cdd:pfam00266 276 IEKHE-----HELAQYL-YERLLSLPGIRLYGPERR--ASIISFNFKG 315
|
|
| SufS_like |
cd06453 |
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP) ... |
110-241 |
1.54e-08 |
|
Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine; and selenocysteine lyase catalyzes the decomposition of L-selenocysteine.
Pssm-ID: 99746 [Multi-domain] Cd Length: 373 Bit Score: 55.93 E-value: 1.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 110 KAGDHVICSRAVFGS-IVALfeKYIA-KFGVDITFVDLS-----DLNAWKNAVRPETKLLFVESPSNPLAEIADIQALAD 182
Cdd:cd06453 86 KPGDEIVTSVMEHHSnIVPW--QQLAeRTGAKLKVVPVDddgqlDLEALEKLLTERTKLVAVTHVSNVLGTINPVKEIGE 163
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1660651604 183 IAHANGALLAVDNSFCTPVLqqPL---KLGADLVIYSATKYLDGQGralGGAVVGNHQLLEE 241
Cdd:cd06453 164 IAHEAGVPVLVDGAQSAGHM--PVdvqDLGCDFLAFSGHKMLGPTG---IGVLYGKEELLEE 220
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
80-241 |
1.81e-08 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 55.92 E-value: 1.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 80 KRLAALDGAERA---VATSSGMGAILSIAMAY--LKAGDHVICSRAVFGS-IVALFEKyIAKFGVDITFVDLS-----DL 148
Cdd:COG0520 66 EKVARFIGAASPdeiIFTRGTTEAINLVAYGLgrLKPGDEILITEMEHHSnIVPWQEL-AERTGAEVRVIPLDedgelDL 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 149 NAWKNAVRPETKLLFVESPSNPLAEIADIQALADIAHANGALLAVDnsFCTPVLQQPL---KLGADLVIYSATKyldgqg 225
Cdd:COG0520 145 EALEALLTPRTKLVAVTHVSNVTGTVNPVKEIAALAHAHGALVLVD--GAQSVPHLPVdvqALGCDFYAFSGHK------ 216
|
170 180
....*....|....*....|
gi 1660651604 226 rALG----GAVVGNHQLLEE 241
Cdd:COG0520 217 -LYGptgiGVLYGKRELLEA 235
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
85-253 |
5.53e-08 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 54.37 E-value: 5.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 85 LDGAErAVATSSGMGAILSIAMAYLKAGDHVICSRAVFgSIVALFEKyiaKFGVDITFVDLSD--------LNAWKNAVR 156
Cdd:PRK06225 81 LDDDE-ALITAGATESLYLVMRAFLSPGDNAVTPDPGY-LIIDNFAS---RFGAEVIEVPIYSeecnykltPELVKENMD 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 157 PETKLLFVESPSNPLA---EIADIQALADIAHANGALLAVDNSFCTPVLQQPLKLGAD----LVIYSATKYLDGQGRALg 229
Cdd:PRK06225 156 ENTRLIYLIDPLNPLGssyTEEEIKEFAEIARDNDAFLLHDCTYRDFAREHTLAAEYApehtVTSYSFSKIFGMAGLRI- 234
|
170 180
....*....|....*....|....*
gi 1660651604 230 GAVVGNHQLLEEVFS-VVRTLGPSM 253
Cdd:PRK06225 235 GAVVATPDLIEVVKSiVINDLGTNV 259
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
79-188 |
2.99e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 51.87 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 79 EKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALfekyIAKFGVDITFVDLS--------DLNA 150
Cdd:PRK06108 75 SRLHGVATPPERIAVTSSGVQALMLAAQALVGPGDEVVAVTPLWPNLVAA----PKILGARVVCVPLDfggggwtlDLDR 150
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1660651604 151 WKNAVRPETKLLFVESPSNPL---AEIADIQALADIAHANG 188
Cdd:PRK06108 151 LLAAITPRTRALFINSPNNPTgwtASRDDLRAILAHCRRHG 191
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
133-229 |
5.69e-07 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 51.29 E-value: 5.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 133 IAKFGVDITFVDLSDLnawKNAVRPETKLLFVESPsNPLAEIADIQALADIAHANGALLAVdnsFCTPV----LQQPLKL 208
Cdd:PRK00451 182 VVEVPYEDGVTDLEAL---EAAVDDDTAAVVVQYP-NFFGVIEDLEEIAEIAHAGGALFIV---GVDPVslglLKPPGEY 254
|
90 100
....*....|....*....|.
gi 1660651604 209 GADLVIysatkyldGQGRALG 229
Cdd:PRK00451 255 GADIVV--------GEGQPLG 267
|
|
| DegT_DnrJ_EryC1 |
pfam01041 |
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all ... |
71-241 |
1.40e-06 |
|
DegT/DnrJ/EryC1/StrS aminotransferase family; The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA, StsC and StsS. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyzes the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin.
Pssm-ID: 395827 Cd Length: 360 Bit Score: 49.97 E-value: 1.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 71 TNPTVSMFEKRLAALDGAERAVATSSGMGAILsIAMAYLKA--GDHVICSRAVFGSIVALfekyIAKFGVDITFVDLS-- 146
Cdd:pfam01041 22 TGPYVREFERAFAAYLGVKHAIAVSSGTAALH-LALRALGVgpGDEVITPSFTFVATANA----ALRLGAKPVFVDIDpd 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 147 ----DLNAWKNAVRPETKLLFvesPSNPLAEIADIQALADIAHANGALLAVD--NSFCTPVLQQPLKLGADLVIYS--AT 218
Cdd:pfam01041 97 tyniDPEAIEAAITPRTKAII---PVHLYGQPADMDAIRAIAARHGLPVIEDaaHALGATYQGKKVGTLGDAATFSfhPT 173
|
170 180
....*....|....*....|....
gi 1660651604 219 KYLD-GQgralGGAVVGNHQLLEE 241
Cdd:pfam01041 174 KNLTtGE----GGAVVTNDPELAE 193
|
|
| GcvP1 |
COG0403 |
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport ... |
85-214 |
1.68e-06 |
|
Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain is part of the Pathway/BioSystem: Glycine cleavage
Pssm-ID: 440172 [Multi-domain] Cd Length: 442 Bit Score: 49.64 E-value: 1.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 85 LDGAErAVATSSGMgailsiAMAYLKAGDHVICSRAVFGSIVALFEKYIAKFGVDITFVD----LSDLNAWKNAVRPETK 160
Cdd:COG0403 135 YDGAT-AAAEAMLM------ARRVTKRSNKVLVSEDVHPQTRAVLKTYAEPLGIEVVEVPdedgVTDLEALKALLDDDVA 207
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1660651604 161 LLFVESPsNPLAEIADIQALADIAHANGALLAVdnsFCTP----VLQQPLKLGADLVI 214
Cdd:COG0403 208 GVLVQYP-NFFGVIEDLRAIAEAAHAAGALVIV---AADPlslgLLKPPGELGADIVV 261
|
|
| KBL_like |
cd06454 |
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ... |
43-284 |
5.77e-06 |
|
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.
Pssm-ID: 99747 [Multi-domain] Cd Length: 349 Bit Score: 47.94 E-value: 5.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 43 TSSFVYENAAEAAAKFSGQVQGniySRF---TNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICSR 119
Cdd:cd06454 16 NHPEVIEAAKEALDKYGVGAGG---SRLisgTSDLHEELEEELAEFHGKEAALVFSSGYAANDGVLSTLAGKGDLIISDS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 120 AVFGSIV-------AlfEKYIAKFGvditfvDLSDLNA-WKNAVRPETKLLFV-ESPSNPLAEIADIQALADIAHANGAL 190
Cdd:cd06454 93 LNHASIIdgirlsgA--KKRIFKHN------DMEDLEKlLREARRPYGKKLIVtEGVYSMDGDIAPLPELVDLAKKYGAI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 191 LAVDNSFCTPVL-------QQPLKLGADLVIYSATkyldgQGRAL---GGAVVGNHQLLEEVFSVVRTL--GPSMSPFNA 258
Cdd:cd06454 165 LFVDEAHSVGVYgphgrgvEEFGGLTDDVDIIMGT-----LGKAFgavGGYIAGSKELIDYLRSYARGFifSTSLPPAVA 239
|
250 260
....*....|....*....|....*....
gi 1660651604 259 WIFLKGLETLR---LRMKAHCENAQKLAE 284
Cdd:cd06454 240 AAALAALEVLQggpERRERLQENVRYLRR 268
|
|
| AHBA_syn |
cd00616 |
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal ... |
71-196 |
7.11e-06 |
|
3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.
Pssm-ID: 99740 [Multi-domain] Cd Length: 352 Bit Score: 47.54 E-value: 7.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 71 TNPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAY-LKAGDHVICSR----AVFGSIVALfekyiakfGVDITFVDL 145
Cdd:cd00616 16 LGPKVREFEKAFAEYLGVKYAVAVSSGTAALHLALRALgIGPGDEVIVPSftfvATANAILLL--------GATPVFVDI 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1660651604 146 S------DLNAWKNAVRPETKLLFvesPSNPLAEIADIQALADIAHANGALLAVDNS 196
Cdd:cd00616 88 DpdtyniDPELIEAAITPRTKAII---PVHLYGNPADMDAIMAIAKRHGLPVIEDAA 141
|
|
| WecE |
COG0399 |
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis]; |
69-191 |
1.48e-05 |
|
dTDP-4-amino-4,6-dideoxygalactose transaminase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440168 Cd Length: 364 Bit Score: 46.60 E-value: 1.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 69 RFTN-PTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAY-LKAGDHVICS----RAVFGSIVAL-----Fekyiakfg 137
Cdd:COG0399 25 WLTLgPEVKEFEEEFAAYLGVKHAVAVSSGTAALHLALRALgIGPGDEVITPaftfVATANAILYVgatpvF-------- 96
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1660651604 138 VDITFVDLS-DLNAWKNAVRPETKLLFvesPSNPLAEIADIQALADIAHANGALL 191
Cdd:COG0399 97 VDIDPDTYNiDPEALEAAITPRTKAII---PVHLYGQPADMDAIMAIAKKHGLKV 148
|
|
| Beta_elim_lyase |
pfam01212 |
Beta-eliminating lyase; |
72-289 |
2.00e-05 |
|
Beta-eliminating lyase;
Pssm-ID: 426128 [Multi-domain] Cd Length: 288 Bit Score: 46.05 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 72 NPTVSMFEKRLAALDGAERAVATSSGMGAILSIAMAYLKAGDHVICSRAvfgSIVALFE-KYIAKFGvDITFVDLS---- 146
Cdd:pfam01212 31 DPTVNRLEDRVAELFGKEAALFVPSGTAANQLALMAHCQRGDEVICGEP---AHIHFDEtGGHAELG-GVQPRPLDgdea 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 147 ---DLNAWKNAVR-------PETKLLFVESPSN-------PLAEIADIQAladIAHANGALLAVD------NSFCTPVLQ 203
Cdd:pfam01212 107 gnmDLEDLEAAIRevgadifPPTGLISLENTHNsaggqvvSLENLREIAA---LAREHGIPVHLDgarfanAAVALGVIV 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 204 QPLKLGADLVIYSATKyldGQGRALGGAVVGNHQLLEEVFSVVRTLGPSMS----PFNAWIFLKGLETLRLRmKAHcENA 279
Cdd:pfam01212 184 KEITSYADSVTMCLSK---GLGAPVGSVLAGSDDFIAKAIRQRKYLGGGLRqagvLAAAGLRALEEGVARLA-RDH-ATA 258
|
250
....*....|
gi 1660651604 280 QKLAEWLSTH 289
Cdd:pfam01212 259 RRLAEGLELL 268
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
104-197 |
3.59e-05 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 45.51 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 104 IAMAYLKAGDHVICSRAVFGsivaLFEKYIAKFGVDITFVDLS-----DLNAWKNAVRPETKLLFVESPSNPLAEIADIQ 178
Cdd:PRK05166 104 ICRAVLRPGDRVVTLYPSFP----LHEDYPTMMGARVERVTVTpdlgfDLDALCAAVARAPRMLMFSNPSNPVGSWLTAD 179
|
90 100
....*....|....*....|.
gi 1660651604 179 ALADIAHANGA--LLAVDNSF 197
Cdd:PRK05166 180 QLARVLDATPPetLIVVDEAY 200
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
88-194 |
8.92e-05 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 44.16 E-value: 8.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 88 AERAVATSSGMGAILSIAMAYLKAGDHVIcsrAVFGSIVALFEkyIAK-FGVDITFVDLSDLNAW-------KNAVRPET 159
Cdd:PRK07324 80 PENILQTNGATGANFLVLYALVEPGDHVI---SVYPTYQQLYD--IPEsLGAEVDYWQLKEENGWlpdldelRRLVRPNT 154
|
90 100 110
....*....|....*....|....*....|....*...
gi 1660651604 160 KLLFVESPSNPLAEIAD---IQALADIAHANGALLAVD 194
Cdd:PRK07324 155 KLICINNANNPTGALMDrayLEEIVEIARSVDAYVLSD 192
|
|
| GDC-P |
cd00613 |
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine ... |
93-219 |
1.28e-04 |
|
Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1.2.10 (GDC) also annotated as glycine cleavage system or glycine synthase. GDC consists of four proteins P, H, L and T. The reaction catalysed by this protein is: Glycine + lipoylprotein <=> S-aminomethyldihydrolipoylprotein + CO2. Alpha-beta-type dimers associate to form an alpha(2)beta(2) tetramer, where the alpha- and beta-subunits are structurally similar and appear to have arisen by gene duplication and subsequent divergence with a loss of one active site. The members of this CD are widely dispersed among all three forms of cellular life.
Pssm-ID: 99737 [Multi-domain] Cd Length: 398 Bit Score: 43.76 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 93 ATSSGMGAILSIAMAYLKAgDHVICSRAVFGSIVALFEKYIAKFGVDITFVDLS-----DLNAWKNAVRPETKLLFVESP 167
Cdd:cd00613 90 ATAAAEAAGLAAIRAYHKR-NKVLVPDSAHPTNPAVARTRGEPLGIEVVEVPSDeggtvDLEALKEEVSEEVAALMVQYP 168
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1660651604 168 sNPLAEIAD-IQALADIAHANGALL--AVDNSFCTpVLQQPLKLGADLVIYSATK 219
Cdd:cd00613 169 -NTLGVFEDlIKEIADIAHSAGALVyvDGDNLNLT-GLKPPGEYGADIVVGNLQK 221
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
100-198 |
5.70e-04 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 41.82 E-value: 5.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 100 AILSIAMAYLKAGDHVIC---SRAVF--GSIVALFEKYIAKFGVDITFvdLSDLNAWKNAVRPETKLLFVESPSNPLAEI 174
Cdd:PRK09276 105 GIAHIPLAFVNPGDVVLVpdpGYPVYkiGTIFAGGEPYFMPLKEENGF--LPDLDAIPEDVAKKAKLMFINYPNNPTGAV 182
|
90 100
....*....|....*....|....*..
gi 1660651604 175 AD---IQALADIAHANGALLAVDNSFC 198
Cdd:PRK09276 183 ADlefFEEVVDFAKKYDIIVCHDAAYS 209
|
|
| PLN02651 |
PLN02651 |
cysteine desulfurase |
80-184 |
9.01e-04 |
|
cysteine desulfurase
Pssm-ID: 178257 [Multi-domain] Cd Length: 364 Bit Score: 41.18 E-value: 9.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 80 KRLAALDGAERA------VATSSGMGAILSIAMAYLKAGDHVICS----RAVFGSIVALFEKyiakfGVDITFV-----D 144
Cdd:PLN02651 50 AQVAALIGADPKeiiftsGATESNNLAIKGVMHFYKDKKKHVITTqtehKCVLDSCRHLQQE-----GFEVTYLpvksdG 124
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1660651604 145 LSDLNAWKNAVRPETKLLFVESPSNplaEIADIQALADIA 184
Cdd:PLN02651 125 LVDLDELAAAIRPDTALVSVMAVNN---EIGVIQPVEEIG 161
|
|
| Orn_deC_like |
cd00615 |
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
79-274 |
1.22e-03 |
|
Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine decarboxylase (LDC). ODC is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. ADC catalyzes the decarboxylation of arginine and LDC catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life.
Pssm-ID: 99739 [Multi-domain] Cd Length: 294 Bit Score: 40.31 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 79 EKRLAALDGAERA-VATSSGMGAILSIAMAYLKAGDHVICSRAVFGSIVALF------EKYI-----AKFGVdITFVDLS 146
Cdd:cd00615 65 QELAARAFGAKHTfFLVNGTSSSNKAVILAVCGPGDKILIDRNCHKSVINGLvlsgavPVYLkpernPYYGI-AGGIPPE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1660651604 147 DLnawKNAV--RPETKLLFVESPsNPLAEIADIQALADIAHANGALLAVDNS----FC-TPVLQ-QPLKLGADLVIYSAT 218
Cdd:cd00615 144 TF---KKALieHPDAKAAVITNP-TYYGICYNLRKIVEEAHHRGLPVLVDEAhgahFRfHPILPsSAAMAGADIVVQSTH 219
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1660651604 219 KYLDG--QGRAL---GGAVvgNHQLLEEVFSVVRTLGPS---MSPFNAWIFLKGLETLRLRMKA 274
Cdd:cd00615 220 KTLPAltQGSMIhvkGDLV--NPDRVNEALNLHQSTSPSyliLASLDVARAMMALEGKELVEEL 281
|
|
| |
