|
Name |
Accession |
Description |
Interval |
E-value |
| PRK07006 |
PRK07006 |
isocitrate dehydrogenase; Reviewed |
9-416 |
0e+00 |
|
isocitrate dehydrogenase; Reviewed
Pssm-ID: 180792 Cd Length: 409 Bit Score: 828.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 9 PADGDKITVKaDLSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYG--TYMPE 86
Cdd:PRK07006 1 PAEGEKITVN-NGKLNVPNNPIIPFIEGDGIGPDITPAMLKVVDAAVEKAYKGERKISWMEIYAGEKATKVYGedVWLPE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 87 ETFEALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIYAGIEWK 166
Cdd:PRK07006 80 ETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYFKGVPSPVKRPEDTDMVIFRENSEDIYAGIEWK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 167 ADSEEAKKVIKFLQEEMGVTKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGY 246
Cdd:PRK07006 160 AGSAEAKKVIKFLQEEMGVKKIRFPETSGIGIKPVSEEGTERLVRAAIEYAIDNDRKSVTLVHKGNIMKFTEGAFKDWGY 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 247 ELALDRFGGELIDGGPWVKIKNPKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGA 326
Cdd:PRK07006 240 QLAEEEFGDELIDGGPWDKIKNPETGKEIIVKDSIADAFLQQILLRPAEYDVIATMNLNGDYISDALAAQVGGIGIAPGA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 327 NIGGAIAVYEATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLMPGATLLRCS 406
Cdd:PRK07006 320 NINDGHAIFEATHGTAPKYAGLDKVNPGSVILSAEMMLRHMGWTEAADLIIKSMEKTIASKTVTYDFARLMEGATEVKCS 399
|
410
....*....|
gi 1666140833 407 EFGDAIIQHM 416
Cdd:PRK07006 400 EFGDALIKNM 409
|
|
| Icd |
COG0538 |
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part ... |
11-418 |
0e+00 |
|
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440304 Cd Length: 409 Bit Score: 768.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 11 DGDKITVkADLSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYGTYMPEETFE 90
Cdd:COG0538 2 EGEKIKV-EDGKLKVPDNPIIPFIEGDGIGPEITRAIWKVIDAAVEKAYGGKRDIEWKEVDAGEKARDETGDWLPDETAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 91 ALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIYAGIEWKADSE 170
Cdd:COG0538 81 AIKEYGVGIKGPLTTPVGGGWRSLNVTIRQILDLYVCRRPVRYFKGVPSPVKHPEKVDIVIFRENTEDIYAGIEWKAGSP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 171 EAKKVIKFLQEEMGVTKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGYELAL 250
Cdd:COG0538 161 EALKLIFFLEDEMGVTVIRFPEDSGIGIKPVSDEGTERLVRAAIQYALDNKRKSVTLVHKGNIMKFTEGAFKDWGYEVAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 251 DRFGGELIDGGPWVKIKNPKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIG- 329
Cdd:COG0538 241 EEFGDKFITEGPWEKYKGPKPAGKIVYKDRIADDMLQQILLRPGEYDVIATKNLNGDYISDALAAQVGGLGIAPGANIGd 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 330 GAIAVYEATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLMPGATLLRCSEFG 409
Cdd:COG0538 321 DGGAEFEATHGTAPKYAGKDSTNPGSLILSGTMMLRHRGWLEAADLIEKAVEKTIESGKVTYDLARLMEGATELSTSEFG 400
|
....*....
gi 1666140833 410 DAIIQHMED 418
Cdd:COG0538 401 DAIIENLDK 409
|
|
| prok_nadp_idh |
TIGR00183 |
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent ... |
3-416 |
0e+00 |
|
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent dehydrogenases, including 3-isopropylmalate dehydrogenase, tartrate dehydrogenase, and the multimeric forms of isocitrate dehydrogenase, share a nucleotide binding domain unrelated to that of lactate dehydrogenase and its homologs. These enzymes dehydrogenate their substates at a H-C-OH site adjacent to a H-C-COOH site; Prokaryotic NADP-dependent isocitrate dehydrogenases resemble their NAD-dependent counterparts and 3-isopropylmalate dehydrogenase (an NAD-dependent enzyme) more closely than they resemble eukaryotic NADP-dependent isocitrate dehydrogenases. [Energy metabolism, TCA cycle]
Pssm-ID: 272948 Cd Length: 416 Bit Score: 740.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 3 YQKIVVPADGDKITVKADlSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYGT 82
Cdd:TIGR00183 2 YEKVKPPAQGEKITYENG-KLNVPNNPIIPYIEGDGIGVDVTPAAIKVLDAAVEKAYKGEKKIVWFEVYAGEKAYQLYGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 83 --YMPEETFEALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIY 160
Cdd:TIGR00183 81 dqWLPADTLDAIKEYRVAIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYYKGVPSPVKHPEKVDMVIFRENTEDIY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 161 AGIEWKADSEEAKKVIKFLQEEMGVTKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGA 240
Cdd:TIGR00183 161 AGIEWAEGSEEAKKLIRFLQNELGVKKIRFPEDSGIGIKPISEEGTKRLVRAAIEYAIENDRKSVTLVHKGNIMKFTEGA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 241 FKEWGYELALDRFGGELIDGGPWVKIKNPKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGI 320
Cdd:TIGR00183 241 FRDWGYELAKKEFGAECITWGLWDKYKNPNPGKEIVIKDRIADAFLQQILTRPDEYDVIATMNLNGDYISDALAAQVGGI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 321 GIAPGANIGGAIAVYEATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLMPGA 400
Cdd:TIGR00183 321 GIAPGANIGDEIGIFEATHGTAPKYAGQDKVNPGSIILSGEMMLEHMGWKEAADLIKKAMEKAIASKIVTYDFARLMDGA 400
|
410
....*....|....*.
gi 1666140833 401 TLLRCSEFGDAIIQHM 416
Cdd:TIGR00183 401 KEVKCSEFAEAIIENM 416
|
|
| Iso_dh |
pfam00180 |
Isocitrate/isopropylmalate dehydrogenase; |
30-412 |
2.44e-95 |
|
Isocitrate/isopropylmalate dehydrogenase;
Pssm-ID: 425507 Cd Length: 346 Bit Score: 289.58 E-value: 2.44e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 30 IIPFIEGDGIGVDITPAMKKVVDAAILKAYggkRSIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPLTTPVG- 108
Cdd:pfam00180 1 KIAVLPGDGIGPEVMAAALKVLKAALEKAP---LEFEFEERDVGGAAIDETGEPLPDETLEACKKADAVLLGAVGGPKWd 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 109 -GGIRSLN--VALRQELDLYVCVRPVRWFQ--GVPSPVQ-HPELTDMVIFRENSEDIYAGIEwKADSEEAKKVikflqee 182
Cdd:pfam00180 78 pAGVRPENglLALRKELGLFANLRPAKVFPplGDASPLKnEVEGVDIVIVRELTGGIYFGIE-KGIKGSGNEV------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 183 mgvtkirfpegcGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGafkeWGYELAldrfggELIDggp 262
Cdd:pfam00180 150 ------------AVDTKLYSRDEIERIARVAFELARKRGRKKVTSVDKANVLKSSDL----WRKIVT------EVAK--- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 263 wvkiknpKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIG-GAIAVYEATHGT 341
Cdd:pfam00180 205 -------AEYPDVELEHQLVDNAAMQLVKNPSQFDVIVTPNLFGDILSDEASMLTGSLGLLPSASLGaNGFGIFEPVHGS 277
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1666140833 342 APKYAGQDKVNPGSIILSAEMMLR-DMGWTEAADLIIKGISGAIAAKTVTYDferLMPGATLLRCSEFGDAI 412
Cdd:pfam00180 278 APDIAGKGIANPIATILSAAMMLRySLGLEDAADKIEAAVLKVLESGIRTGD---LAGSATYVSTSEFGEAV 346
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK07006 |
PRK07006 |
isocitrate dehydrogenase; Reviewed |
9-416 |
0e+00 |
|
isocitrate dehydrogenase; Reviewed
Pssm-ID: 180792 Cd Length: 409 Bit Score: 828.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 9 PADGDKITVKaDLSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYG--TYMPE 86
Cdd:PRK07006 1 PAEGEKITVN-NGKLNVPNNPIIPFIEGDGIGPDITPAMLKVVDAAVEKAYKGERKISWMEIYAGEKATKVYGedVWLPE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 87 ETFEALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIYAGIEWK 166
Cdd:PRK07006 80 ETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYFKGVPSPVKRPEDTDMVIFRENSEDIYAGIEWK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 167 ADSEEAKKVIKFLQEEMGVTKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGY 246
Cdd:PRK07006 160 AGSAEAKKVIKFLQEEMGVKKIRFPETSGIGIKPVSEEGTERLVRAAIEYAIDNDRKSVTLVHKGNIMKFTEGAFKDWGY 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 247 ELALDRFGGELIDGGPWVKIKNPKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGA 326
Cdd:PRK07006 240 QLAEEEFGDELIDGGPWDKIKNPETGKEIIVKDSIADAFLQQILLRPAEYDVIATMNLNGDYISDALAAQVGGIGIAPGA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 327 NIGGAIAVYEATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLMPGATLLRCS 406
Cdd:PRK07006 320 NINDGHAIFEATHGTAPKYAGLDKVNPGSVILSAEMMLRHMGWTEAADLIIKSMEKTIASKTVTYDFARLMEGATEVKCS 399
|
410
....*....|
gi 1666140833 407 EFGDAIIQHM 416
Cdd:PRK07006 400 EFGDALIKNM 409
|
|
| Icd |
COG0538 |
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part ... |
11-418 |
0e+00 |
|
Isocitrate dehydrogenase [Energy production and conversion]; Isocitrate dehydrogenase is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440304 Cd Length: 409 Bit Score: 768.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 11 DGDKITVkADLSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYGTYMPEETFE 90
Cdd:COG0538 2 EGEKIKV-EDGKLKVPDNPIIPFIEGDGIGPEITRAIWKVIDAAVEKAYGGKRDIEWKEVDAGEKARDETGDWLPDETAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 91 ALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIYAGIEWKADSE 170
Cdd:COG0538 81 AIKEYGVGIKGPLTTPVGGGWRSLNVTIRQILDLYVCRRPVRYFKGVPSPVKHPEKVDIVIFRENTEDIYAGIEWKAGSP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 171 EAKKVIKFLQEEMGVTKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGYELAL 250
Cdd:COG0538 161 EALKLIFFLEDEMGVTVIRFPEDSGIGIKPVSDEGTERLVRAAIQYALDNKRKSVTLVHKGNIMKFTEGAFKDWGYEVAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 251 DRFGGELIDGGPWVKIKNPKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIG- 329
Cdd:COG0538 241 EEFGDKFITEGPWEKYKGPKPAGKIVYKDRIADDMLQQILLRPGEYDVIATKNLNGDYISDALAAQVGGLGIAPGANIGd 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 330 GAIAVYEATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLMPGATLLRCSEFG 409
Cdd:COG0538 321 DGGAEFEATHGTAPKYAGKDSTNPGSLILSGTMMLRHRGWLEAADLIEKAVEKTIESGKVTYDLARLMEGATELSTSEFG 400
|
....*....
gi 1666140833 410 DAIIQHMED 418
Cdd:COG0538 401 DAIIENLDK 409
|
|
| prok_nadp_idh |
TIGR00183 |
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent ... |
3-416 |
0e+00 |
|
isocitrate dehydrogenase, NADP-dependent, prokaryotic type; Several NAD- or NADP-dependent dehydrogenases, including 3-isopropylmalate dehydrogenase, tartrate dehydrogenase, and the multimeric forms of isocitrate dehydrogenase, share a nucleotide binding domain unrelated to that of lactate dehydrogenase and its homologs. These enzymes dehydrogenate their substates at a H-C-OH site adjacent to a H-C-COOH site; Prokaryotic NADP-dependent isocitrate dehydrogenases resemble their NAD-dependent counterparts and 3-isopropylmalate dehydrogenase (an NAD-dependent enzyme) more closely than they resemble eukaryotic NADP-dependent isocitrate dehydrogenases. [Energy metabolism, TCA cycle]
Pssm-ID: 272948 Cd Length: 416 Bit Score: 740.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 3 YQKIVVPADGDKITVKADlSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYGT 82
Cdd:TIGR00183 2 YEKVKPPAQGEKITYENG-KLNVPNNPIIPYIEGDGIGVDVTPAAIKVLDAAVEKAYKGEKKIVWFEVYAGEKAYQLYGQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 83 --YMPEETFEALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIY 160
Cdd:TIGR00183 81 dqWLPADTLDAIKEYRVAIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPVRYYKGVPSPVKHPEKVDMVIFRENTEDIY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 161 AGIEWKADSEEAKKVIKFLQEEMGVTKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGA 240
Cdd:TIGR00183 161 AGIEWAEGSEEAKKLIRFLQNELGVKKIRFPEDSGIGIKPISEEGTKRLVRAAIEYAIENDRKSVTLVHKGNIMKFTEGA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 241 FKEWGYELALDRFGGELIDGGPWVKIKNPKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGI 320
Cdd:TIGR00183 241 FRDWGYELAKKEFGAECITWGLWDKYKNPNPGKEIVIKDRIADAFLQQILTRPDEYDVIATMNLNGDYISDALAAQVGGI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 321 GIAPGANIGGAIAVYEATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLMPGA 400
Cdd:TIGR00183 321 GIAPGANIGDEIGIFEATHGTAPKYAGQDKVNPGSIILSGEMMLEHMGWKEAADLIKKAMEKAIASKIVTYDFARLMDGA 400
|
410
....*....|....*.
gi 1666140833 401 TLLRCSEFGDAIIQHM 416
Cdd:TIGR00183 401 KEVKCSEFAEAIIENM 416
|
|
| PRK07362 |
PRK07362 |
NADP-dependent isocitrate dehydrogenase; |
3-415 |
0e+00 |
|
NADP-dependent isocitrate dehydrogenase;
Pssm-ID: 180944 Cd Length: 474 Bit Score: 555.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 3 YQKIVVPADGDKITVKaDLSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYGT 82
Cdd:PRK07362 4 YEKLTPPSTGSKITFK-NGKPVVPDNPIIPFIRGDGTGVDIWPATQKVLDAAVAKAYGGERKINWFKVYAGDEACDLYGT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 83 --YMPEETFEALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIY 160
Cdd:PRK07362 83 yqYLPEDTLEAIREYGVAIKGPLTTPIGGGIRSLNVALRQIFDLYSCVRPCRYYAGTPSPHKNPEKLDVIVYRENTEDIY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 161 AGIEWKADSEEAKKVIKFLQEEM-----GVTKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFA--IDNDKPSVTLVHKGNI 233
Cdd:PRK07362 163 MGIEWEAGDEIGDKLIKHLNEEVipaspELGKRQIPLGSGIGIKPVSKTGSQRHIRRAIEHAlrLPGDKRHVTLVHKGNI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 234 MKYTEGAFKEWGYELALDRFGGELI-DGGPWV---KIKNPK--------------------------------------- 270
Cdd:PRK07362 243 MKYTEGAFRDWGYELATTEFRDECVtERESWIlsnKEKNPNisiednarmiepgydsltpekkaaicaevkevldsiwss 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 271 --NGK---DIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIGGAIAVYEATHGTAPKY 345
Cdd:PRK07362 323 hgNGKwkeKVLVDDRIADSIFQQIQTRPQEYSILATLNLNGDYISDAAAAIVGGLGMAPGANIGDNAAIFEATHGTAPKH 402
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1666140833 346 AGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLM-PGATLLRCSEFGDAIIQH 415
Cdd:PRK07362 403 AGLDRINPGSVILSGVMMLEYLGWQEAADLITKGLSAAIANKQVTYDLARLMePPVDPLSCSEFAEAIISH 473
|
|
| PRK06451 |
PRK06451 |
NADP-dependent isocitrate dehydrogenase; |
8-417 |
4.70e-160 |
|
NADP-dependent isocitrate dehydrogenase;
Pssm-ID: 235803 Cd Length: 412 Bit Score: 456.99 E-value: 4.70e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 8 VPADGDKITVKaDLSLNVPNHPIIPFIEGDGIGVDITPAMKKVVDAAILKAYGGKRSIEWMEVYCGEKANKIYGTYMPEE 87
Cdd:PRK06451 4 IPEDGEVIKFE-NGKWIVPKKPIILYVEGDGIGPEITHAAMKVINKAVEKAYGSDREIKWVEVLAGDKAEKLTGNRFPKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 88 TFEALREFVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIYAGIEWKA 167
Cdd:PRK06451 83 SEELIEKYRVLLKGPLETPIGKGWKSINVAIRLMLDLYANIRPVKYIPGIESPLKNPEKIDLIIFRENTDDLYRGIEYPY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 168 DSEEAKKVIKFLQEEMgvtKIRFPEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGYE 247
Cdd:PRK06451 163 DSEEAKKIRDFLRKEL---GVEVEDDTGIGIKLISKFKTQRIARMAIKYAIDHKRKKVTIMHKGNVMKYTEGAFREWAYE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 248 LALDRFGGELIDGGPWVKIKNPKN-GKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGA 326
Cdd:PRK06451 240 VALKEFRDYVVTEEEVTKNYNGVPpSGKVIINDRIADNMFQQIIIRPDEYDIILAPNVNGDYISDAAGALVGNIGMLGGA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 327 NIGGAIAVYEATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFERLMpGATLLRCS 406
Cdd:PRK06451 320 NIGDTGGMFEAIHGTAPKYAGKNVANPTGIIKGGELMLRFMGWDKAADLIDKAIMESIKQKKVTQDLARFM-GVRALSTT 398
|
410
....*....|.
gi 1666140833 407 EFGDAIIQHME 417
Cdd:PRK06451 399 EYTDELISIID 409
|
|
| LeuB |
COG0473 |
Isocitrate/isopropylmalate dehydrogenase [Energy production and conversion, Amino acid ... |
34-416 |
5.11e-99 |
|
Isocitrate/isopropylmalate dehydrogenase [Energy production and conversion, Amino acid transport and metabolism]; Isocitrate/isopropylmalate dehydrogenase is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 440241 Cd Length: 346 Bit Score: 298.85 E-value: 5.11e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 34 IEGDGIGVDITPAMKKVVDAAilkAYGGKRSIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPLTTPV---GGG 110
Cdd:COG0473 7 LPGDGIGPEVVAAALKVLEAA---AERFGLDFEFEEADIGGAAYDKTGTPLPDETLEALRKADAILLGAVGGPKwddGVR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 111 IRSLNVALRQELDLYVCVRPVRWFQGVPSPVQH--PELTDMVIFRENSEDIYAGIEWKADSEEAKKVikflqeemgvtki 188
Cdd:COG0473 84 PESGLLALRKELDLYANLRPAKLYPGLPSPLKPeiVEGIDLVIVRENTEGLYFGIGGRIGTGTGEEV------------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 189 rfpegcGIGIKPVSKEGTQRLVRKAIQFAIDNDKpSVTLVHKGNIMKYTEGAFKEWGYELAldrfggelidggpwvkikn 268
Cdd:COG0473 151 ------AIDTRVYTRKGIERIARYAFELARKRRK-KVTSVDKANVLKLTSGLWREVVREVA------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 269 pKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIG-GAIAVYEATHGTAPKYAG 347
Cdd:COG0473 205 -KEYPDVELDHMYVDAAAMQLVRNPEQFDVIVTENLFGDILSDLAAGLTGSLGLAPSANIGdEGKALFEPVHGSAPDIAG 283
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1666140833 348 QDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDferLMPGATllrCSEFGDAIIQHM 416
Cdd:COG0473 284 KGIANPIATILSAAMMLRHLGEEEAADAIEAAVEKVLAEGVRTPD---LGGKAG---TSEMGDAIIAAL 346
|
|
| Iso_dh |
pfam00180 |
Isocitrate/isopropylmalate dehydrogenase; |
30-412 |
2.44e-95 |
|
Isocitrate/isopropylmalate dehydrogenase;
Pssm-ID: 425507 Cd Length: 346 Bit Score: 289.58 E-value: 2.44e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 30 IIPFIEGDGIGVDITPAMKKVVDAAILKAYggkRSIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPLTTPVG- 108
Cdd:pfam00180 1 KIAVLPGDGIGPEVMAAALKVLKAALEKAP---LEFEFEERDVGGAAIDETGEPLPDETLEACKKADAVLLGAVGGPKWd 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 109 -GGIRSLN--VALRQELDLYVCVRPVRWFQ--GVPSPVQ-HPELTDMVIFRENSEDIYAGIEwKADSEEAKKVikflqee 182
Cdd:pfam00180 78 pAGVRPENglLALRKELGLFANLRPAKVFPplGDASPLKnEVEGVDIVIVRELTGGIYFGIE-KGIKGSGNEV------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 183 mgvtkirfpegcGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGafkeWGYELAldrfggELIDggp 262
Cdd:pfam00180 150 ------------AVDTKLYSRDEIERIARVAFELARKRGRKKVTSVDKANVLKSSDL----WRKIVT------EVAK--- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 263 wvkiknpKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIG-GAIAVYEATHGT 341
Cdd:pfam00180 205 -------AEYPDVELEHQLVDNAAMQLVKNPSQFDVIVTPNLFGDILSDEASMLTGSLGLLPSASLGaNGFGIFEPVHGS 277
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1666140833 342 APKYAGQDKVNPGSIILSAEMMLR-DMGWTEAADLIIKGISGAIAAKTVTYDferLMPGATLLRCSEFGDAI 412
Cdd:pfam00180 278 APDIAGKGIANPIATILSAAMMLRySLGLEDAADKIEAAVLKVLESGIRTGD---LAGSATYVSTSEFGEAV 346
|
|
| PRK08997 |
PRK08997 |
isocitrate dehydrogenase; Provisional |
31-416 |
6.98e-71 |
|
isocitrate dehydrogenase; Provisional
Pssm-ID: 181606 Cd Length: 334 Bit Score: 226.52 E-value: 6.98e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 31 IPFIEGDGIGVDITPAMKKVVDAAilkayggKRSIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPLTTPVGGG 110
Cdd:PRK08997 5 ITVIPGDGIGPSIIDATLKILDKL-------GCDFEYEFADAGLTALEKHGELLPQRTLDLIEKNKIALKGPLTTPVGEG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 111 IRSLNVALRQELDLYVCVRPVRWFQGVPSPVqhpELTDMVIFRENSEDIYAGI--EWKADSEEAKKVIKflqeemgvtki 188
Cdd:PRK08997 78 FTSINVTLRKKFDLYANVRPVLSFPGTKARY---DNIDIITVRENTEGMYSGEgqTVSEDGETAEATSI----------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 189 rfpegcgigikpVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGYELALDRfggelidggpwvkikn 268
Cdd:PRK08997 144 ------------ITRKGAERIVRFAYELARKEGRKKVTAVHKANIMKSTSGLFLKVAREVALRY---------------- 195
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 269 pkngKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIGGAIAVYEATHGTAPKYAGQ 348
Cdd:PRK08997 196 ----PDIEFEEMIVDATCMQLVMNPEQFDVIVTTNLFGDILSDLCAGLVGGLGMAPGANIGRDAAIFEAVHGSAPDIAGK 271
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1666140833 349 DKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKtvtydfERLMP-----GATllrcSEFGDAIIQHM 416
Cdd:PRK08997 272 NLANPTSVILAAIQMLEYLGMPDKAERIRKAIVAVIEAG------DRTTRdlggtHGT----TDFTQAVIDRL 334
|
|
| PRK09222 |
PRK09222 |
NADP-dependent isocitrate dehydrogenase; |
31-414 |
4.57e-67 |
|
NADP-dependent isocitrate dehydrogenase;
Pssm-ID: 236416 [Multi-domain] Cd Length: 482 Bit Score: 220.92 E-value: 4.57e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 31 IPFIEGDGIGVDITPAMKKvvdaaILKAYGGKRSIEWMEVycGEKANKIYGTY-MPEETFEALREFVVSIKGPLTTPVGG 109
Cdd:PRK09222 7 ITVAYGDGIGPEIMEAVLK-----ILEAAGAPLEIETIEI--GEKVYKKGWTSgISPSAWESIRRTKVLLKAPITTPQGG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 110 GIRSLNVALRQELDLYVCVRPVR-WFQGVPSPvqHPELtDMVIFRENSEDIYAGIEWK--ADSEEAKKVIkflqeemgvt 186
Cdd:PRK09222 80 GYKSLNVTLRKTLGLYANVRPCVsYHPFVETK--HPNL-DVVIIRENEEDLYAGIEHRqtPDVYQCLKLI---------- 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 187 kirfpegcgigikpvSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEwgyelALDRFGGELIDggpwvkI 266
Cdd:PRK09222 147 ---------------SRPGSEKIIRYAFEYARANGRKKVTCLTKDNIMKLTDGLFHK-----VFDEIAKEYPD------I 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 267 KNpkngkDIIIKDvIADAflqQILMRPADYSVIATLNLNGDYISDaLAAEV-GGIGIAPGANIGGAIAVYEATHGTAPKY 345
Cdd:PRK09222 201 EA-----EHYIVD-IGAA---RLATNPENFDVIVTPNLYGDILSD-IAAEIsGSVGLAGSANIGEEYAMFEAVHGSAPDI 270
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1666140833 346 AGQDKVNPGSIILSAEMMLRDMGWTEAADLI----IKGISGAIAaktvTYDFERlmPGATLLRCS--EFGDAIIQ 414
Cdd:PRK09222 271 AGKNIANPSGLLNAAVMMLVHIGQFDIAELIenawLKTLEDGIH----TADIYN--EGVSKKKVGtkEFAEAVIE 339
|
|
| mito_nad_idh |
TIGR00175 |
isocitrate dehydrogenase, NAD-dependent, mitochondrial type; Several NAD- or NADP-dependent ... |
33-416 |
9.62e-67 |
|
isocitrate dehydrogenase, NAD-dependent, mitochondrial type; Several NAD- or NADP-dependent dehydrogenases, including 3-isopropylmalate dehydrogenase, tartrate dehydrogenase, and the multimeric forms of isocitrate dehydrogenase, share a nucleotide binding domain unrelated to that of lactate dehydrogenase and its homologs. These enzymes dehydrogenate their substates at a H-C-OH site adjacent to a H-C-COOH site; the latter carbon, now adjacent to a carbonyl group, readily decarboxylates. Mitochondrial NAD-dependent isocitrate dehydrogenases (IDH) resemble prokaryotic NADP-dependent IDH and 3-isopropylmalate dehydrogenase (an NAD-dependent enzyme) more closely than they resemble eukaryotic NADP-dependent IDH. The mitochondrial NAD-dependent isocitrate dehydrogenase is believed to be an alpha(2)-beta-gamma heterotetramer. All subunits are homologous and found by this model. The NADP-dependent IDH of Thermus aquaticus thermophilus strain HB8 resembles these NAD-dependent IDH, except for the residues involved in cofactor specificity, much more closely than it resembles other prokaryotic NADP-dependent IDH, including that of Thermus aquaticus strain YT1. [Energy metabolism, TCA cycle]
Pssm-ID: 272942 Cd Length: 333 Bit Score: 215.71 E-value: 9.62e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 33 FIEGDGIGVDITPAMKKVVDAAilkayggKRSIEWMEVYCGEKANkiYGTYMPEETFEALREFVVSIKGPLTTPVG-GGI 111
Cdd:TIGR00175 8 LIPGDGIGPEISGSVKKIFRAA-------NVPIEFEEIDVSPQTD--GKTEIPDEAVESIKRNKVALKGPLETPIGkGGH 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 112 RSLNVALRQELDLYVCVRPVRWFQGVPSPvqHPELtDMVIFRENSEDIYAGIEwkadSEEAKKVIKflqeemgvtkirfp 191
Cdd:TIGR00175 79 RSLNVALRKELDLYANVVHCKSLPGFKTR--HEDV-DIVIIRENTEGEYSGLE----HESVPGVVE-------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 192 egcgiGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGYELAldrfggelidggpwvkiknpKN 271
Cdd:TIGR00175 138 -----SLKVITRDKSERIARYAFEYARKNGRKKVTAVHKANIMKLADGLFLNVCREVA--------------------KE 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 272 GKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIGGAIAVYE-ATHGTAPKYAGQDK 350
Cdd:TIGR00175 193 YPDITFESMIVDNTCMQLVSRPSQFDVMVMPNLYGNILSNLGAGLVGGPGLVPGANIGRDYAVFEpGVRHTGPDIAGQNI 272
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1666140833 351 VNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIA-AKTVTYDferLMPGATllrCSEFGDAIIQHM 416
Cdd:TIGR00175 273 ANPTALILSSVMMLNHLGLKEHADRIQKAVLSTIAeGKNRTKD---LGGTAT---TSDFTEAVIKRL 333
|
|
| PRK14025 |
PRK14025 |
multifunctional 3-isopropylmalate dehydrogenase/D-malate dehydrogenase; Provisional |
31-416 |
2.73e-60 |
|
multifunctional 3-isopropylmalate dehydrogenase/D-malate dehydrogenase; Provisional
Pssm-ID: 184462 Cd Length: 330 Bit Score: 198.82 E-value: 2.73e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 31 IPFIEGDGIGVDITPAMKKVVDAAILKayggkrsIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPLTTPVGGG 110
Cdd:PRK14025 4 ICVIEGDGIGKEVVPAALHVLEATGLP-------FEFVYAEAGDEVFEKTGKALPEETIEAAKEADAVLFGAAGETAADV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 111 IrslnVALRQELDLYVCVRPVRWFQGVPSpvQHPELtDMVIFRENSEDIYAGIEWKadseeakkvikflqeemgvtkirF 190
Cdd:PRK14025 77 I----VKLRRILDTYANVRPVKSYKGVKC--LYPDI-DYVIVRENTEGLYKGIEAE-----------------------I 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 191 PEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPS----VTLVHKGNIMKYTEGAFKEWGYELAldrfggelidggpwvki 266
Cdd:PRK14025 127 ADGVTVATRVITRKASERIFRFAFEMAKRRKKMGkegkVTCAHKANVLKKTDGLFKKTFYEVA----------------- 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 267 knpKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIGGAIAVYEATHGTAPKYA 346
Cdd:PRK14025 190 ---KEYPDIKAEDYYVDAMNMYIITRPQTFDVVVTSNLFGDILSDGAAGLVGGLGLAPSANIGDKYGLFEPVHGSAPDIA 266
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 347 GQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYDFerlmpGATlLRCSEFGDAIIQHM 416
Cdd:PRK14025 267 GKGIANPTATILTAVLMLRHLGENEEADKVEKALEEVLALGLTTPDL-----GGN-LSTMEMAEEVAKRV 330
|
|
| PLN00118 |
PLN00118 |
isocitrate dehydrogenase (NAD+) |
36-416 |
8.01e-60 |
|
isocitrate dehydrogenase (NAD+)
Pssm-ID: 215062 Cd Length: 372 Bit Score: 198.95 E-value: 8.01e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 36 GDGIGVDITPAMKKVVDAAilkayggKRSIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPLTTPVGGGIRSLN 115
Cdd:PLN00118 49 GDGIGPEIAESVKQVFTAA-------GVPIEWEEHYVGTTVDPRTGSFLTWESLESVRRNKVGLKGPMATPIGKGHRSLN 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 116 VALRQELDLYVCVRPVrwfQGVPSPVQHPELTDMVIFRENSEDIYAGIEwkadseeaKKVIKflqeemGVTKirfpegcg 195
Cdd:PLN00118 122 LTLRKELGLYANVRPC---YSLPGYKTRYDDVDLVTIRENTEGEYSGLE--------HQVVR------GVVE-------- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 196 iGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGYELAldrfggelidggpwvkIKNPkngkDI 275
Cdd:PLN00118 177 -SLKIITRQASLRVAEYAFHYAKTHGRKRVSAIHKANIMKKTDGLFLKCCREVA----------------EKYP----EI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 276 IIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIG-GAIAVYEATHGTAPKYAGQDKVNPG 354
Cdd:PLN00118 236 VYEEVIIDNCCMMLVKNPALFDVLVMPNLYGDIISDLCAGLIGGLGLTPSCNIGeNGLALAEAVHGSAPDIAGKNLANPT 315
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1666140833 355 SIILSAEMMLRDMGWTEAADLIIKGISGAIA-AKTVTYDferLMPGATllrCSEFGDAIIQHM 416
Cdd:PLN00118 316 ALLLSAVMMLRHLKLNEQAEQIHNAILNTIAeGKYRTAD---LGGSST---TTDFTKAICDHL 372
|
|
| PLN00123 |
PLN00123 |
isocitrate dehydrogenase (NAD+) |
30-417 |
3.03e-48 |
|
isocitrate dehydrogenase (NAD+)
Pssm-ID: 215065 Cd Length: 360 Bit Score: 168.12 E-value: 3.03e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 30 IIPFIEGDGIGVDITPAMKKVVDAAILKAYggkrsIEWMEVYCGEKAnkiygtyMPEETFEALREFVVSIKGPLTTPVGG 109
Cdd:PLN00123 32 AVTLIPGDGIGPLVTGAVEQVMEAMHAPVY-----FERYEVHGDMKK-------VPEEVLESIRRNKVCLKGGLATPVGG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 110 GIRSLNVALRQELDLYVCVRPVRWFQGVPSpvQHPELtDMVIFRENSEDIYAGIEwkadSEEAKKVIKFLqeemgvtkir 189
Cdd:PLN00123 100 GVSSLNVQLRKELDLFASLVNCFNLPGLPT--RHENV-DIVVIRENTEGEYSGLE----HEVVPGVVESL---------- 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 190 fpegcgigiKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYTEGAFKEWGYELAldrfggelidggpwvkiknp 269
Cdd:PLN00123 163 ---------KVITKFCSERIAKYAFEYAYLNNRKKVTAVHKANIMKLADGLFLESCREVA-------------------- 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 270 KNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIGGAIAVYE--ATHGTA--PKY 345
Cdd:PLN00123 214 KKYPGIKYNEIIVDNCCMQLVSKPEQFDVMVTPNLYGNLVANTAAGIAGGTGVMPGGNVGADHAVFEqgASAGNVgnEKL 293
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1666140833 346 AGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIA-AKTVTYDferLMPGATLLrcsEFGDAIIQHME 417
Cdd:PLN00123 294 VEQKKANPVALLLSSAMMLRHLQFPSFADRLETAVKRVIAeGKYRTKD---LGGSSTTQ---EVVDAVIANLD 360
|
|
| PRK00772 |
PRK00772 |
3-isopropylmalate dehydrogenase; Provisional |
34-418 |
6.77e-46 |
|
3-isopropylmalate dehydrogenase; Provisional
Pssm-ID: 234832 Cd Length: 358 Bit Score: 161.81 E-value: 6.77e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 34 IEGDGIGVDITPAMKKVVDAaILKAYGgkRSIEWMEVYCGEKANKIYGTYMPEETFEALREF--VV--SIKGPLTTPVGG 109
Cdd:PRK00772 8 LPGDGIGPEVMAEAVKVLDA-VAEKFG--FDFEFEEALVGGAAIDAHGVPLPEETLEACRAAdaVLlgAVGGPKWDNLPP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 110 GIRSLN--VALRQELDLYVCVRPVRWFQGV--PSPVQhPEL---TDMVIFRENSEDIYAGiewkadseEAKKVIKFLQEE 182
Cdd:PRK00772 85 DVRPERglLALRKELGLFANLRPAKLYPGLadASPLK-PEIvagLDILIVRELTGGIYFG--------EPRGREGLGGEE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 183 MGVTKIRFpegcgigikpvSKEGTQRLVRKAIQFAIDNDKpSVTLVHKGNIMKYTEgAFKEWGYELAldrfggelidggp 262
Cdd:PRK00772 156 RAFDTMVY-----------TREEIERIARVAFELARKRRK-KVTSVDKANVLESSR-LWREVVTEVA------------- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 263 wvkiknpKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIG-GAIAVYEATHGT 341
Cdd:PRK00772 210 -------KEYPDVELSHMYVDNAAMQLVRNPKQFDVIVTENLFGDILSDEAAMLTGSLGMLPSASLGeSGPGLYEPIHGS 282
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1666140833 342 APKYAGQDKVNPGSIILSAEMMLRD-MGWTEAADLIIKGISGAIAAKTVTYDferLMPGATLLRCSEFGDAIIQHMED 418
Cdd:PRK00772 283 APDIAGKGIANPIATILSAAMMLRYsLGLEEAADAIEAAVEKVLAQGYRTAD---IAEGGGKVSTSEMGDAILAALAE 357
|
|
| PRK03437 |
PRK03437 |
3-isopropylmalate dehydrogenase; Provisional |
34-416 |
1.18e-44 |
|
3-isopropylmalate dehydrogenase; Provisional
Pssm-ID: 179579 Cd Length: 344 Bit Score: 158.17 E-value: 1.18e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 34 IEGDGIGVDITPAMKKVVDAAIlkayGGKRSIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPLTTP-VGGGI- 111
Cdd:PRK03437 10 IPGDGIGPEVVAEALKVLDAVA----AGGPGVETTEYDLGARRYLRTGETLPDSVLAELRQHDAILLGAIGDPsVPSGVl 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 112 -RSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIYAGIEwkadseeakkvikflqeemGVTKIRF 190
Cdd:PRK03437 86 eRGLLLKLRFALDHYVNLRPSKLYPGVTSPLAGPGDIDFVVVREGTEGPYTGNG-------------------GALRVGT 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 191 PEGCGIGIKPVSKEGTQRLVRKAIQFAIDNDKPSVTLVHKGNIMKYtegAFKEWgyELALDRFGGELidggpwvkiknPk 270
Cdd:PRK03437 147 PHEVATEVSVNTAFGVERVVRDAFERAQKRPRKHLTLVHKTNVLTF---AGDLW--QRTVDEVAAEY-----------P- 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 271 ngkDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANI---GGAIAVYEATHGTAPKYAG 347
Cdd:PRK03437 210 ---DVTVDYQHVDAATIFMVTDPSRFDVIVTDNLFGDIITDLAAAVTGGIGLAASGNInptGTNPSMFEPVHGSAPDIAG 286
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1666140833 348 QDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKtvtydferlmpGATLLRCSEFGDAIIQHM 416
Cdd:PRK03437 287 QGIADPTAAILSVALLLDHLGEEDAAARIEAAVEADLAER-----------GKMGRSTAEVGDRIAARL 344
|
|
| PRK08194 |
PRK08194 |
tartrate dehydrogenase; Provisional |
31-392 |
4.88e-34 |
|
tartrate dehydrogenase; Provisional
Pssm-ID: 181281 Cd Length: 352 Bit Score: 129.84 E-value: 4.88e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 31 IPFIEGDGIGVDITPAMKKVVDAaILKAYGG----KRSIEWMEVYCGEkankiYGTYMPEETFEALRE----FVVSIKGP 102
Cdd:PRK08194 6 IAVIPGDGVGKEVVPAAVRVLKA-VAEVHGGlkfeFTEFPWSCEYYLE-----HGEMMPEDGLEQLKQfdaiFLGAVGNP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 103 LTTPVGGGIRSLNVALRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFRENSEDIYAGIEWKADSEEakkvikflqEE 182
Cdd:PRK08194 80 KLVPDHISLWGLLIKIRREFEQVINIRPAKQLRGIKSPLANPKDFDLLVVRENSEGEYSEVGGRIHRGE---------DE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 183 MGVTKIRFpegcgigikpvSKEGTQRLVRKAIQFAiDNDKPSVTLVHKGN----IMKYTEGAFKEWGyelaldrfggeli 258
Cdd:PRK08194 151 IAIQNAVF-----------TRKGTERAMRYAFELA-AKRRKHVTSATKSNgivhSMPFWDEVFQEVG------------- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 259 dggpwvkiknpKNGKDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANI---GGAIAVY 335
Cdd:PRK08194 206 -----------KDYPEIETDSQHIDALAAFFVTRPEEFDVIVASNLFGDILTDIGAAIMGSIGIAPAANInvnGKYPSMF 274
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1666140833 336 EATHGTAPKYAGQDKVNPGSIILSAEMMLRDMGWTEAADLIIKGISGAIAAKTVTYD 392
Cdd:PRK08194 275 EPVHGSAPDIAGKGIANPIGQIWTAKLMLDHFGEEELGSHLLDVIEDVTEDGIKTPD 331
|
|
| PLN02329 |
PLN02329 |
3-isopropylmalate dehydrogenase |
31-417 |
2.69e-18 |
|
3-isopropylmalate dehydrogenase
Pssm-ID: 215188 Cd Length: 409 Bit Score: 86.28 E-value: 2.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 31 IPFIEGDGIGVDITPAMKKVVDAAilkAYGGKRSIEWMEVYCGEKANKIYGTYMPEETFEALREFVVSIKGPlttpVGGG 110
Cdd:PLN02329 49 IALLPGDGIGPEVISVAKNVLQKA---GSLEGLEFDFQEMPVGGAALDLVGVPLPEETFTAAKQSDAILLGA----IGGY 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 111 IRSLNVA-LRQELDLYVCVRPVRWFQGVPSPVQHPELTDMVIFREnseDIYAGIEWKADSEEAKKVikFLQEEMGVTKIR 189
Cdd:PLN02329 122 KWDKNEKhLRPEMALFYLRRDLKVFANLRPATVLPQLVDASTLKK---EVAEGVDMMIVRELTGGI--YFGEPRGITINE 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 190 FPEGCGIGIKPVSKEGTQRLVRKAIQFAiDNDKPSVTLVHKGNIMKytegAFKEWGYELAldrfggELIDGGPwvkiknp 269
Cdd:PLN02329 197 NGEEVGVSTEIYAAHEIDRIARVAFETA-RKRRGKLCSVDKANVLD----ASILWRKRVT------ALASEYP------- 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 270 kngkDIIIKDVIADAFLQQILMRPADYSVIATLNLNGDYISDALAAEVGGIGIAPGANIGGA-IAVYEATHGTAPKYAGQ 348
Cdd:PLN02329 259 ----DVELSHMYVDNAAMQLIRDPKQFDTIVTNNIFGDILSDEASMITGSIGMLPSASLGESgPGLFEPIHGSAPDIAGQ 334
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1666140833 349 DKVNPGSIILSAEMMLR-DMGWTEAADLIIKGISGAIAAKTVTYDFerLMPGATLLRCSEFGDAIIQHME 417
Cdd:PLN02329 335 DKANPLATILSAAMLLKyGLGEEKAAKRIEDAVVDALNKGFRTGDI--YSPGNKLVGCKEMGEEVLKSVD 402
|
|
| |
