|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
4-331 |
0e+00 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 575.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 4 KKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQ 83
Cdd:PRK00927 1 KKRVLSGIQPTGKLHLGNYLGAIKNWVELQDEYECFFCIADLHALTVPQDPEELRENTRELAADYLACGIDPEKSTIFVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 84 SHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDLAN 163
Cdd:PRK00927 81 SHVPEHAELAWILNCITPLGELERMTQFKDKSAKQKENVSAGLFTYPVLMAADILLYKADLVPVGEDQKQHLELTRDIAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 164 RFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIKRKIKRSVTDSLGVVKY---NDEQPG 240
Cdd:PRK00927 161 RFNNLYGEVFPVPEPLIPKVGARVMGLDGPTKKMSKSDPNDNNTINLLDDPKTIAKKIKKAVTDSERLREIrydLPNKPE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 241 IKNLIDIYSNLSKKSVEEIVNMYE--GKGYGIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKT 318
Cdd:PRK00927 241 VSNLLTIYSALSGESIEELEAEYEagGKGYGDFKKDLAEAVVEFLAPIRERYEELLADPAYLDEILAEGAEKARAVASKT 320
|
330
....*....|...
gi 1689781891 319 LRKVYKKVGFIER 331
Cdd:PRK00927 321 LKEVREAMGLLRK 333
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
2-329 |
0e+00 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 538.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 2 SEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIF 81
Cdd:COG0180 1 MSKKRVLSGIQPTGRLHLGNYLGALKNWVELQDEYECFFFIADLHALTTPQDPEELRENTREVAADYLAAGLDPEKSTIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 82 IQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQK-SEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD 160
Cdd:COG0180 81 VQSDVPEHAELAWLLSCLTPLGELERMPQFKDKSAKnGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLELTRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 161 LANRFNNRFSPTFVVPEGYYPKGGARVMSLqEPTKKMSKSDSNenaFILLADDSDSIKRKIKRSVTDSLGvVKYNDE-QP 239
Cdd:COG0180 161 IARRFNHRYGEVFPEPEALIPEEGARIPGL-DGRKKMSKSYGN---TINLLDDPKEIRKKIKSAVTDSER-LRYDDPgKP 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 240 GIKNLIDIYSNLS-KKSVEEIVNMYE--GKGYGIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQAR 316
Cdd:COG0180 236 EVCNLFTIYSAFSgKEEVEELEAEYRagGIGYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEILAEGAEKARAIAA 315
|
330
....*....|...
gi 1689781891 317 KTLRKVYKKVGFI 329
Cdd:COG0180 316 KTLAEVREAMGLL 328
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
7-281 |
2.88e-135 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 385.40 E-value: 2.88e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGKMTLGNYLGAIKNWTELQD-NYDCYYSIVDLHAITVPQ-DPKVLRANAIELLAQYIACGLDPEKNTIFIQS 84
Cdd:cd00806 2 VLSGIQPSGSLHLGHYLGAFRFWVWLQEaGYELFFFIADLHALTVKQlDPEELRQNTRENAKDYLACGLDPEKSTIFFQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 85 HVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEaNLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDLANR 164
Cdd:cd00806 82 DVPEHYELAWLLSCVVTFGELERMTGFKDKSAQGE-SVNIGLLTYPVLQAADILLYKACLVPVGIDQDPHLELTRDIARR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 165 FNNRFSPTFVVPEGYYPKgGARVMSLQEPTKKMSKSDsNENAfILLADDSDSIKRKIKRSVTDSLGVVKYNDE-QPGIKN 243
Cdd:cd00806 161 FNKLYGEIFPKPAALLSK-GAFLPGLQGPSKKMSKSD-PNNA-IFLTDSPKEIKKKIMKAATDGGRTEHRRDGgGPGVSN 237
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1689781891 244 LIDIYSNLSKKSVEEIV----NMYEGKGYGIFKEDVAEVVSE 281
Cdd:cd00806 238 LVEIYSAFFNDDDEELEeideYRSGGLGYGECKKLLAEAIQE 279
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
3-328 |
1.25e-126 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 365.50 E-value: 1.25e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 3 EKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVPQ-DPKVLRANAIELLAQYIACGLDPEKNTIF 81
Cdd:TIGR00233 1 KKFRVLTGIQPSGKMHLGHYLGAIQTKWLQQFGVELFICIADLHAITVKQtDPDALRKAREELAADYLAVGLDPEKTFIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 82 IQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQksEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDL 161
Cdd:TIGR00233 81 LQSDYPEHYELAWLLSCQVTFGELKRMTQFKDKSQ--AENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRDL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 162 ANRFNNRFSPTFVVPEGYYPKGGARVMSLQepTKKMSKSDsnENAFILLADDSDSIKRKIKRSVTDSLGVVKYND-EQPG 240
Cdd:TIGR00233 159 AERFNKKFKNFFPKPESLISKFFPRLMGLS--GKKMSKSD--PNSAIFLTDTPKQIKKKIRKAATDGGRVTLFEHrEKPG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 241 IKNLIDIYSNLSKKS-----VEEIVNMY-EGK-GYGIFKEDVAEVVSEALRPIREKYVDLLNnkDYLEKIYSMGAEKAEK 313
Cdd:TIGR00233 235 VPNLLVIYQYLSFFLidddkLKEIYEAYkSGKlGYGECKKALIEVLQEFLKEIQERRAEIAE--EILDKILEPGAKKARE 312
|
330
....*....|....*
gi 1689781891 314 QARKTLRKVYKKVGF 328
Cdd:TIGR00233 313 TANKTLADVYKAMGL 327
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
7-283 |
1.13e-79 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 244.49 E-value: 1.13e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGKMTLGnYLGAIKNWTELQDN-YDCYYSIVDLHAITVPQD---PKVLRANAIELLA---QYIACGLDPEKNT 79
Cdd:pfam00579 8 VYSGIDPTGPLHLG-YLVPLMKLRQFQQAgHEVFFLIGDLHAIIGDPSkspERKLLSRETVLENaikAQLACGLDPEKAE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 80 IFIQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEAN--LNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLEL 157
Cdd:pfam00579 87 IVNNSDWLEHLELAWLLRDLGKHFSLNRMLQFKDVKKRLEQGpgISLGEFTYPLLQAYDILLLKADLQPGGSDQWGNIEL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 158 ARDLANRFNNRFsptFVVPEGYYPKggarVMSLQEPTKKMSKSDSneNAFILLADDSDSIKRKIKRSVTDSLGVV-KYND 236
Cdd:pfam00579 167 GRDLARRFNKKI---FKKPVGLTNP----LLTGLDGGKKMSKSAG--NSAIFLDDDPESVYKKIQKAYTDPDREVrKDLK 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1689781891 237 EQPGIKN-LIDIYSNLS----KKSVEEIVNMYEGK--GYGIFKEDVAEVVSEAL 283
Cdd:pfam00579 238 LFTFLSNeEIEILEAELgkspYREAEELLAREVTGlvHGGDLKKAAAEAVNKLL 291
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
4-331 |
0e+00 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 575.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 4 KKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQ 83
Cdd:PRK00927 1 KKRVLSGIQPTGKLHLGNYLGAIKNWVELQDEYECFFCIADLHALTVPQDPEELRENTRELAADYLACGIDPEKSTIFVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 84 SHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDLAN 163
Cdd:PRK00927 81 SHVPEHAELAWILNCITPLGELERMTQFKDKSAKQKENVSAGLFTYPVLMAADILLYKADLVPVGEDQKQHLELTRDIAR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 164 RFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIKRKIKRSVTDSLGVVKY---NDEQPG 240
Cdd:PRK00927 161 RFNNLYGEVFPVPEPLIPKVGARVMGLDGPTKKMSKSDPNDNNTINLLDDPKTIAKKIKKAVTDSERLREIrydLPNKPE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 241 IKNLIDIYSNLSKKSVEEIVNMYE--GKGYGIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKT 318
Cdd:PRK00927 241 VSNLLTIYSALSGESIEELEAEYEagGKGYGDFKKDLAEAVVEFLAPIRERYEELLADPAYLDEILAEGAEKARAVASKT 320
|
330
....*....|...
gi 1689781891 319 LRKVYKKVGFIER 331
Cdd:PRK00927 321 LKEVREAMGLLRK 333
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
2-329 |
0e+00 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 538.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 2 SEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIF 81
Cdd:COG0180 1 MSKKRVLSGIQPTGRLHLGNYLGALKNWVELQDEYECFFFIADLHALTTPQDPEELRENTREVAADYLAAGLDPEKSTIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 82 IQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQK-SEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD 160
Cdd:COG0180 81 VQSDVPEHAELAWLLSCLTPLGELERMPQFKDKSAKnGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLELTRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 161 LANRFNNRFSPTFVVPEGYYPKGGARVMSLqEPTKKMSKSDSNenaFILLADDSDSIKRKIKRSVTDSLGvVKYNDE-QP 239
Cdd:COG0180 161 IARRFNHRYGEVFPEPEALIPEEGARIPGL-DGRKKMSKSYGN---TINLLDDPKEIRKKIKSAVTDSER-LRYDDPgKP 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 240 GIKNLIDIYSNLS-KKSVEEIVNMYE--GKGYGIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQAR 316
Cdd:COG0180 236 EVCNLFTIYSAFSgKEEVEELEAEYRagGIGYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEILAEGAEKARAIAA 315
|
330
....*....|...
gi 1689781891 317 KTLRKVYKKVGFI 329
Cdd:COG0180 316 KTLAEVREAMGLL 328
|
|
| PLN02886 |
PLN02886 |
aminoacyl-tRNA ligase |
4-332 |
1.21e-143 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215478 [Multi-domain] Cd Length: 389 Bit Score: 411.13 E-value: 1.21e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 4 KKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQ 83
Cdd:PLN02886 46 KKRVVSGVQPTGSIHLGNYLGAIKNWVALQETYDTFFCVVDLHAITLPHDPRELGKATRSTAAIYLACGIDPSKASVFVQ 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 84 SHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKS-EANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDLA 162
Cdd:PLN02886 126 SHVPAHAELMWLLSCSTPIGWLNKMIQFKEKSRKAgDENVGVGLLTYPVLMASDILLYQADLVPVGEDQKQHLELTRDIA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 163 NRFNNRFS------------PTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIKRKIKRSVTDSLG 230
Cdd:PLN02886 206 ERVNNLYGgrkwkklggrggSVFKVPEALIPPAGARVMSLTDGTSKMSKSAPSDQSRINLLDPPDVIANKIKRCKTDSFP 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 231 VVKY-NDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAE 309
Cdd:PLN02886 286 GLEFdNPERPECNNLLSIYQLVTGKTKEEVLAECGDMRWGDFKPLLTDALIEHLSPIQVRYEEIMSDPSYLDSVLKEGAD 365
|
330 340
....*....|....*....|...
gi 1689781891 310 KAEKQARKTLRKVYKKVGFIERR 332
Cdd:PLN02886 366 AAAEIADRTLANVYQAMGFVQRR 388
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
7-281 |
2.88e-135 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 385.40 E-value: 2.88e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGKMTLGNYLGAIKNWTELQD-NYDCYYSIVDLHAITVPQ-DPKVLRANAIELLAQYIACGLDPEKNTIFIQS 84
Cdd:cd00806 2 VLSGIQPSGSLHLGHYLGAFRFWVWLQEaGYELFFFIADLHALTVKQlDPEELRQNTRENAKDYLACGLDPEKSTIFFQS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 85 HVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEaNLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDLANR 164
Cdd:cd00806 82 DVPEHYELAWLLSCVVTFGELERMTGFKDKSAQGE-SVNIGLLTYPVLQAADILLYKACLVPVGIDQDPHLELTRDIARR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 165 FNNRFSPTFVVPEGYYPKgGARVMSLQEPTKKMSKSDsNENAfILLADDSDSIKRKIKRSVTDSLGVVKYNDE-QPGIKN 243
Cdd:cd00806 161 FNKLYGEIFPKPAALLSK-GAFLPGLQGPSKKMSKSD-PNNA-IFLTDSPKEIKKKIMKAATDGGRTEHRRDGgGPGVSN 237
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1689781891 244 LIDIYSNLSKKSVEEIV----NMYEGKGYGIFKEDVAEVVSE 281
Cdd:cd00806 238 LVEIYSAFFNDDDEELEeideYRSGGLGYGECKKLLAEAIQE 279
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
3-328 |
1.25e-126 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 365.50 E-value: 1.25e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 3 EKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVPQ-DPKVLRANAIELLAQYIACGLDPEKNTIF 81
Cdd:TIGR00233 1 KKFRVLTGIQPSGKMHLGHYLGAIQTKWLQQFGVELFICIADLHAITVKQtDPDALRKAREELAADYLAVGLDPEKTFIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 82 IQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQksEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDL 161
Cdd:TIGR00233 81 LQSDYPEHYELAWLLSCQVTFGELKRMTQFKDKSQ--AENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLELTRDL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 162 ANRFNNRFSPTFVVPEGYYPKGGARVMSLQepTKKMSKSDsnENAFILLADDSDSIKRKIKRSVTDSLGVVKYND-EQPG 240
Cdd:TIGR00233 159 AERFNKKFKNFFPKPESLISKFFPRLMGLS--GKKMSKSD--PNSAIFLTDTPKQIKKKIRKAATDGGRVTLFEHrEKPG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 241 IKNLIDIYSNLSKKS-----VEEIVNMY-EGK-GYGIFKEDVAEVVSEALRPIREKYVDLLNnkDYLEKIYSMGAEKAEK 313
Cdd:TIGR00233 235 VPNLLVIYQYLSFFLidddkLKEIYEAYkSGKlGYGECKKALIEVLQEFLKEIQERRAEIAE--EILDKILEPGAKKARE 312
|
330
....*....|....*
gi 1689781891 314 QARKTLRKVYKKVGF 328
Cdd:TIGR00233 313 TANKTLADVYKAMGL 327
|
|
| PRK12282 |
PRK12282 |
tryptophanyl-tRNA synthetase II; Reviewed |
4-322 |
6.87e-99 |
|
tryptophanyl-tRNA synthetase II; Reviewed
Pssm-ID: 183400 [Multi-domain] Cd Length: 333 Bit Score: 295.23 E-value: 6.87e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 4 KKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAIT-VPQDPKVLRANAIELLAQYIACGLDPEKNTIFI 82
Cdd:PRK12282 2 KPIILTGDRPTGKLHLGHYVGSLKNRVALQNEHEQFVLIADQQALTdNAKNPEKIRRNILEVALDYLAVGIDPAKSTIFI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 83 QSHVKEHVELMWVLNTMTYMGELSRMTQFKDK-SQKS-EANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD 160
Cdd:PRK12282 82 QSQIPELAELTMYYMNLVTVARLERNPTVKTEiAQKGfGRSIPAGFLTYPVSQAADITAFKATLVPVGDDQLPMIEQTRE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 161 LANRFNNRF-SPTFVVPEGYYPKGGaRVMSLqEPTKKMSKSDSNEnafILLADDSDSIKRKIKRSVTDSlGVVKYNDE-Q 238
Cdd:PRK12282 162 IVRRFNSLYgTDVLVEPEALLPEAG-RLPGL-DGKAKMSKSLGNA---IYLSDDADTIKKKVMSMYTDP-NHIRVEDPgK 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 239 PGIKNLIDIYS--NLSKKSVEEIVNMYEGKGYGIF--KEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQ 314
Cdd:PRK12282 236 VEGNVVFTYLDafDPDKAEVAELKAHYQRGGLGDVkcKRYLEEVLQELLAPIRERRAEFAKDPGYVLEILKAGSEKAREV 315
|
....*...
gi 1689781891 315 ARKTLRKV 322
Cdd:PRK12282 316 AAQTLSEV 323
|
|
| PRK12556 |
PRK12556 |
tryptophanyl-tRNA synthetase; Provisional |
4-328 |
6.90e-82 |
|
tryptophanyl-tRNA synthetase; Provisional
Pssm-ID: 183592 [Multi-domain] Cd Length: 332 Bit Score: 251.56 E-value: 6.90e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 4 KKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDC--YYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIF 81
Cdd:PRK12556 3 EKIMLTGIKPTGYPHLGNYIGAIKPALQMAKNYEGkaLYFIADYHALNAVHDPEQFRSYTREVAATWLSLGLDPEDVIFY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 82 IQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKS-------EANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQH 154
Cdd:PRK12556 83 RQSDVPEIFELAWILSCLTPKGLMNRAHAYKAKVDQNkeagldlDAGVNMGLYTYPILMAADILLFQATHVPVGKDQIQH 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 155 LELARDLANRFNNRFSPTFVVPEGYYPKGGARVMSLQepTKKMSKSDSNEnafILLADDSDSIKRKIKRSVTDSLGVVKY 234
Cdd:PRK12556 163 IEIARDIATYFNHTFGDTFTLPEYVIQEEGAILPGLD--GRKMSKSYGNV---IPLFAEQEKLRKLIFKIKTDSSLPNEP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 235 NDeqPGIKNLIDIYSNLSKKS-VEEIVNMYE-GKGYGIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAE 312
Cdd:PRK12556 238 KD--PETSALFTIYKEFATEEeVQSMREKYEtGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPSLLDEALEKGAERAR 315
|
330
....*....|....*.
gi 1689781891 313 KQARKTLRKVYKKVGF 328
Cdd:PRK12556 316 EIAKPNLAEIKKAIGF 331
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
7-283 |
1.13e-79 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 244.49 E-value: 1.13e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGKMTLGnYLGAIKNWTELQDN-YDCYYSIVDLHAITVPQD---PKVLRANAIELLA---QYIACGLDPEKNT 79
Cdd:pfam00579 8 VYSGIDPTGPLHLG-YLVPLMKLRQFQQAgHEVFFLIGDLHAIIGDPSkspERKLLSRETVLENaikAQLACGLDPEKAE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 80 IFIQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEAN--LNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLEL 157
Cdd:pfam00579 87 IVNNSDWLEHLELAWLLRDLGKHFSLNRMLQFKDVKKRLEQGpgISLGEFTYPLLQAYDILLLKADLQPGGSDQWGNIEL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 158 ARDLANRFNNRFsptFVVPEGYYPKggarVMSLQEPTKKMSKSDSneNAFILLADDSDSIKRKIKRSVTDSLGVV-KYND 236
Cdd:pfam00579 167 GRDLARRFNKKI---FKKPVGLTNP----LLTGLDGGKKMSKSAG--NSAIFLDDDPESVYKKIQKAYTDPDREVrKDLK 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 1689781891 237 EQPGIKN-LIDIYSNLS----KKSVEEIVNMYEGK--GYGIFKEDVAEVVSEAL 283
Cdd:pfam00579 238 LFTFLSNeEIEILEAELgkspYREAEELLAREVTGlvHGGDLKKAAAEAVNKLL 291
|
|
| PRK12283 |
PRK12283 |
tryptophanyl-tRNA synthetase; Reviewed |
7-327 |
1.05e-64 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 183401 [Multi-domain] Cd Length: 398 Bit Score: 209.42 E-value: 1.05e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVDLHAITVP-QDPKVLRANAIELLAQYIACGLDPEKNTIFIQSH 85
Cdd:PRK12283 5 VLSGMRPTGRLHLGHYHGVLKNWVKLQHEYECFFFVADWHALTTHyETPEVIEKNVWDMVIDWLAAGVDPAQATLFIQSK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 86 VKEHVELMWVLNTMTYMGELSRMTQFKDKSQK-SEANLNA-GLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDLAN 163
Cdd:PRK12283 85 VPEHAELHLLLSMITPLGWLERVPTYKDQQEKlKEKDLSTyGFLGYPLLQSADILIYRAGLVPVGEDQVPHVEMTREIAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 164 RFNNRF--SPTF-------VVPEG-------------YYPKG-------------------------------GARVMSL 190
Cdd:PRK12283 165 RFNHLYgrEPGFeekaeaaIKKLGkkraklyhelrnaYQEEGddealeqarallqeqqnlsmgdrerlfgyleGAGKIIL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 191 QEP----TK----------KMSKSDSNenaFILLADDSDSIKRKIKRSVTDSlGVVKYNDeqPG------IKNLIDIYSN 250
Cdd:PRK12283 245 PEPqallTEaskmpgldgqKMSKSYGN---TIGLREDPESVTKKIRTMPTDP-ARVRRTD--PGdpekcpVWQLHQVYSD 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 251 lskKSVEEIVnmYEG-KGYGI----FKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKK 325
Cdd:PRK12283 319 ---EETKEWV--QKGcRSAGIgcleCKQPVIDAILREQQPMRERAQKYEDDPSLVRAIVADGCEKARKVARETMRDVREA 393
|
..
gi 1689781891 326 VG 327
Cdd:PRK12283 394 MG 395
|
|
| PRK12284 |
PRK12284 |
tryptophanyl-tRNA synthetase; Reviewed |
7-327 |
9.78e-58 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237036 [Multi-domain] Cd Length: 431 Bit Score: 192.53 E-value: 9.78e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGKMTLGNYLGAIKNWTE--LQDNYDCYYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKNTIFIQS 84
Cdd:PRK12284 5 VLTGITTTGTPHLGNYAGAIRPAIAasRQPGVESFYFLADYHALIKCDDPARIQRSTLEIAATWLAAGLDPERVTFYRQS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 85 HVKEHVELMWVLNTMTYMGELSRMTQFK---DKSQKS----EANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLEL 157
Cdd:PRK12284 85 DIPEIPELTWLLTCVAGKGLLNRAHAYKaavDKNVAAgedpDAGVTAGLFMYPVLMAADILMFNAHKVPVGRDQIQHIEM 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 158 ARDLANRFNNRFSPT-FVVPEGYYPKGGARVMSLQepTKKMSKSDSNEnafILLADDSDSIKRKIKRSVTDSL--GVVKy 234
Cdd:PRK12284 165 ARDIAQRFNHLYGGEfFVLPEAVIEESVATLPGLD--GRKMSKSYDNT---IPLFAPREELKKAIFSIVTDSRapGEPK- 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 235 ndeQPGIKNLIDIYSNLSkkSVEEIVNM----YEGKGYGIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEK 310
Cdd:PRK12284 239 ---DTEGSALFQLYQAFA--TPEETAAFrqalADGIGWGDAKQRLFERIDRELAPMRERYEALIARPADIEDILLAGAAK 313
|
330
....*....|....*..
gi 1689781891 311 AEKQARKTLRKVYKKVG 327
Cdd:PRK12284 314 ARRIATPFLAELREAVG 330
|
|
| Tyr_Trp_RS_core |
cd00395 |
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA ... |
7-281 |
1.27e-54 |
|
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS)/Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. These enzymes attach Tyr or Trp, respectively, to the appropriate tRNA. These class I enzymes are homodimers, which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173893 [Multi-domain] Cd Length: 273 Bit Score: 179.81 E-value: 1.27e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGK-MTLGNYLGaIKNWTELQDN-YDCYYSIVDLHAITV----------PQDPKVLRANAIELLAQYIACGLD 74
Cdd:cd00395 2 LYCGIDPTADsLHIGHLIG-LLTFRRFQHAgHRPIFLIGGQTGIIGdpsgkksertLNDPEEVRQNIRRIAAQYLAVGIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 75 --PEKNTIFIQSHV---KEHVELMWVLNTMTYMGELSRMTQFKdksQKSEANLNAGLFTYPVLMAADILLYQT----DLV 145
Cdd:cd00395 81 edPTQATLFNNSDWpgpLAHIQFLRDLGKHVYVNYMERKTSFQ---SRSEEGISATEFTYPPLQAADFLLLNTtegcDIQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 146 PVGDDQKQHLELARDLANRFNNrfsptFVVPEGYYPkggARVMSLQEPtkKMSKSDSNENAFILLADDSDSIKRKIKRSV 225
Cdd:cd00395 158 PGGSDQWGNITLGRELARRFNG-----FTIAEGLTI---PLVTKLDGP--KFGKSESGPKWLDTEKTSPYEFYQFWINAV 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 226 tdslgvvkyndeqpgIKNLIDIYSNLSKKSVEEI----VNMYEGKGYGIFKEDVAEVVSE 281
Cdd:cd00395 228 ---------------DSDVINILKYFTFLSKEEIerleQEQYEAPGYRVAQKTLAEEVTK 272
|
|
| PRK12285 |
PRK12285 |
tryptophanyl-tRNA synthetase; Reviewed |
7-226 |
1.47e-23 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237037 [Multi-domain] Cd Length: 368 Bit Score: 99.55 E-value: 1.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 7 IFSGAQPSGKMTLGNYLGAIK-NWteLQD-NYDCYYSIVDLHAITVP-QDPKVLRANAIELLAQYIACGLDPEKNTIFIQ 83
Cdd:PRK12285 69 VYTGFMPSGPMHIGHKMVFDElKW--HQEfGANVYIPIADDEAYAARgLSWEETREWAYEYILDLIALGFDPDKTEIYFQ 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 84 SHVKEHVELMWVLNTMTYMGELSRMTQFKDKSqkseanlNAGLFTYPVLMAADILLYQTD------LVPVGDDQKQHLEL 157
Cdd:PRK12285 147 SENIKVYDLAFELAKKVNFSELKAIYGFTGET-------NIGHIFYPATQAADILHPQLEegpkptLVPVGIDQDPHIRL 219
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1689781891 158 ARDLANRFNNRFSptFVVPEGYYPK------GGarvmslqeptkKMSKsdSNENAFILLADDSDSIKRKIKRSVT 226
Cdd:PRK12285 220 TRDIAERLHGGYG--FIKPSSTYHKfmpgltGG-----------KMSS--SKPESAIYLTDDPETVKKKIMKALT 279
|
|
| PRK08560 |
PRK08560 |
tyrosyl-tRNA synthetase; Validated |
3-301 |
9.33e-13 |
|
tyrosyl-tRNA synthetase; Validated
Pssm-ID: 236286 [Multi-domain] Cd Length: 329 Bit Score: 67.97 E-value: 9.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 3 EKKVIFSGAQPSGKMTLGNYLGAIKnWTELQDN-YDCYYSIVDLHA-ITVPQDPKVLRANAIELLAQYIACGLDPEKNTI 80
Cdd:PRK08560 29 EEPKAYIGFEPSGKIHLGHLLTMNK-LADLQKAgFKVTVLLADWHAyLNDKGDLEEIRKVAEYNKKVFEALGLDPDKTEF 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 81 FIQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQ-KQHLeLAR 159
Cdd:PRK08560 108 VLGSEFQLDKEYWLLVLKLAKNTTLARARRSMTIMGRRMEEPDVSKLVYPLMQVADIFYLDVDIAVGGMDQrKIHM-LAR 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 160 DLANRFNnRFSP----TFVVPegyypkggarvmSLQEPTKKMSKSDsnENAFILLADDSDSIKRKIKRSVTdSLGVVKYN 235
Cdd:PRK08560 187 EVLPKLG-YKKPvcihTPLLT------------GLDGGGIKMSKSK--PGSAIFVHDSPEEIRRKIKKAYC-PPGEVEGN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 236 ---------------------DEQPGiknlidiySNLSKKSVEEIVNMY-EGKgygI----FKEDVAEVVSEALRPIREK 289
Cdd:PRK08560 251 pvleiakyhifprydpfvierPEKYG--------GDLEYESYEELERDYaEGK---LhpmdLKNAVAEYLIEILEPVREY 319
|
330
....*....|..
gi 1689781891 290 yvdLLNNKDYLE 301
Cdd:PRK08560 320 ---LEEGPELLE 328
|
|
| tyrS |
TIGR00234 |
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ... |
1-319 |
1.64e-08 |
|
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272976 [Multi-domain] Cd Length: 378 Bit Score: 55.48 E-value: 1.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 1 MSEKKVIFSGAQPSG-KMTLGNYLgAIKNWTELQDN-YDCYYSIVDLHA-ITVPQDPKVLR--------ANAIELLAQYI 69
Cdd:TIGR00234 28 LERPLKLYLGFDPTApSLHLGHLV-PLLKLRDFQQAgHEVIVLLGDFTAlIGDPTGKSEVRkiltreevQENAENIKKQI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 70 ACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYMGELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGD 149
Cdd:TIGR00234 107 ARFLDFEKAKFVYNSEWLLKLNYTDFIRLLGKIFTVNRMLRRDAFSSRFEENISLHEFIYPLLQAYDFVYLNVDLQLGGS 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 150 DQKQHLELARDLANRFNNRfsPTFVVPegyypkggarvMSLQEPT--KKMSKSDSN--------ENAFILLADDSDSIKR 219
Cdd:TIGR00234 187 DQWFNIRKGRDLARENLPS--LQFGLT-----------VPLLTPAdgEKMGKSLGGavsldegkYDFYQKVINTPDELVK 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 220 KIKRSVTdSLGVvkynDEQPGIKNLIDIYSNLSKKS-VEEIVNMYEGKGYGI-FKEDVAEVVSEALRPIR------EKYV 291
Cdd:TIGR00234 254 KYLKLFT-FLGL----EEIEQLVELKGPNPREVKENlALEITKYVHGPEAALaAEEISEAIFSGGLNPDEvpifrpEKFG 328
|
330 340
....*....|....*....|....*...
gi 1689781891 292 DLLNNKDYLEKIysmGAEKAEKQARKTL 319
Cdd:TIGR00234 329 GPITLADLLVLS---GLFPSKSEARRDI 353
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
98-281 |
3.42e-08 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 53.76 E-value: 3.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 98 TMTYMgeLSRMTqFKdKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARDLANRFNNRFSPTFVVPe 177
Cdd:cd00805 112 TVNRM--LRRDA-VK-VRLEEEEGISFSEFIYPLLQAYDFVYLDVDLQLGGSDQRGNITLGRDLIRKLGYKKVVGLTTP- 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 178 gyypkggaRVMSLQEptKKMSKSDSNeNAFILLADDSDSIKRKIkRSVTDslgvvkyndeqPGIKNLIDIYSNLSKKSVE 257
Cdd:cd00805 187 --------LLTGLDG--GKMSKSEGN-AIWDPVLDSPYDVYQKI-RNAFD-----------PDVLEFLKLFTFLDYEEIE 243
|
170 180
....*....|....*....|....*
gi 1689781891 258 EIVNMY-EGKGYGIFKEDVAEVVSE 281
Cdd:cd00805 244 ELEEEHaEGPLPRDAKKALAEELTK 268
|
|
| class_I_aaRS_core |
cd00802 |
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA ... |
88-201 |
6.06e-07 |
|
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA synthetase (aaRS) catalytic core domain. These enzymes are mostly monomers which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173901 [Multi-domain] Cd Length: 143 Bit Score: 48.24 E-value: 6.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 88 EHVELMWVLNTMTYMGELSRMT----QFKDKSQKSEANLNAG----LFTYPVLMAADILLYQT---DLVPVGDDQKQHLE 156
Cdd:cd00802 29 AYRKLGYKVRCIALIDDAGGLIgdpaNKKGENAKAFVERWIErikeDVEYMFLQAADFLLLYEtecDIHLGGSDQLGHIE 108
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1689781891 157 LARDLANRFNnrfspTFVVPEGYYPkggARVMSlqEPTKKMSKSD 201
Cdd:cd00802 109 LGLELLKKAG-----GPARPFGLTF---GRVMG--ADGTKMSKSK 143
|
|
| PTZ00348 |
PTZ00348 |
tyrosyl-tRNA synthetase; Provisional |
62-305 |
1.86e-06 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 173541 [Multi-domain] Cd Length: 682 Bit Score: 49.52 E-value: 1.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 62 IELLAQYI-----ACGLDPEKnTIFIQS--HVKEHVELMW--VLNtMTYMGELSRMTQFKDKSQKSEANLNAGLFTYPVL 132
Cdd:PTZ00348 89 IRIVGRYLievwkAAGMDMDK-VLFLWSseEITNHANTYWrtVLD-IGRQNTIARIKKCCTIMGKTEGTLTAAQVLYPLM 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 133 MAADILLYQTDLVPVGDDQKQHLELARDLANRFNNRFSPtfVVPEGYYPKGgarvmsLQEPTKKMSKSDSneNAFILLAD 212
Cdd:PTZ00348 167 QCADIFFLKADICQLGLDQRKVNMLAREYCDLIGRKLKP--VILSHHMLAG------LKQGQAKMSKSDP--DSAIFMED 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 213 DSDSIKRKIKRS-----------VTDSLGVVKYNDE-------------QPGIKNLID-----IYSNLSKKSVEEIVNMY 263
Cdd:PTZ00348 237 TEEDVARKIRQAycprvkqsaseITDDGAPVATDDRnpvldyfqcvvyaRPGAVATIDgttyaTYEDLEQAFVSDEVSEE 316
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1689781891 264 egkgygIFKEDVAEVVSEALRPIREKYVDLLNNKDYLEKIYS 305
Cdd:PTZ00348 317 ------ALKSCLIDEVNALLEPVRQHFASNPEAHELLEAVKS 352
|
|
| PTZ00126 |
PTZ00126 |
tyrosyl-tRNA synthetase; Provisional |
129-310 |
5.06e-06 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 240282 [Multi-domain] Cd Length: 383 Bit Score: 47.76 E-value: 5.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 129 YPVLMAADILLYQTDLVPVGDDQKQHLELARDLANRFNNRFSPTFVvpegyypkGGARVMSLQEPTKKMSKsdSNENAFI 208
Cdd:PTZ00126 198 YPCMQCADIFYLKADICQLGMDQRKVNMLAREYCDKKKIKKKPIIL--------SHHMLPGLLEGQEKMSK--SDPNSAI 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 209 LLADDSDSIKRKIKRSVTDSlGVVKYNDEQPGIKNLIDIYSN---LSKK----------SVEEIVNMY-EGKGY-GIFKE 273
Cdd:PTZ00126 268 FMEDSEEDVNRKIKKAYCPP-GVIEGNPILAYFKSIVFPAFNsftVLRKeknggdvtytTYEELEKDYlSGALHpGDLKP 346
|
170 180 190
....*....|....*....|....*....|....*..
gi 1689781891 274 DVAEVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEK 310
Cdd:PTZ00126 347 ALAKYLNLMLQPVRDHFQNNPEAKSLLSEVKSYKVTK 383
|
|
| PLN02486 |
PLN02486 |
aminoacyl-tRNA ligase |
48-223 |
4.81e-04 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178104 Cd Length: 383 Bit Score: 41.65 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 48 ITVPQDPKVLRANAIELlaqyIACGLDPEKNTIFiqSHVkEHVELMWVLNTMTY-----MGELSRMTQFKDKSqkseanl 122
Cdd:PLN02486 124 LSVEESQRLARENAKDI----IACGFDVERTFIF--SDF-DYVGGAFYKNMVKIakcvtLNQVRGIFGFSGED------- 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1689781891 123 NAGLFTYPVLMAA-------DILLYQTD----LVPVGDDQKQHLELARDLANRF--------NNRFSPtfvvpegyypkg 183
Cdd:PLN02486 190 NIGKISFPAVQAApsfpssfPHLFGGKDklrcLIPCAIDQDPYFRMTRDVAPRLgyykpaliESRFFP------------ 257
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1689781891 184 garvmSLQEPTKKMSKSDSNenAFILLADDSDSIKRKIKR 223
Cdd:PLN02486 258 -----ALQGESGKMSASDPN--SAIYVTDTPKEIKNKINK 290
|
|
| nt_trans |
cd02156 |
nucleotidyl transferase superfamily; nt_trans (nucleotidyl transferase) This superfamily ... |
137-201 |
1.74e-03 |
|
nucleotidyl transferase superfamily; nt_trans (nucleotidyl transferase) This superfamily includes the class I amino-acyl tRNA synthetases, pantothenate synthetase (PanC), ATP sulfurylase, and the cytidylyltransferases, all of which have a conserved dinucleotide-binding domain.
Pssm-ID: 173912 [Multi-domain] Cd Length: 105 Bit Score: 37.52 E-value: 1.74e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1689781891 137 ILLYQTDLVPVGDDQKQHLELARDlanrfNNRFSPTFVVPEGYYPKGGArvmslqEPTKKMSKSD 201
Cdd:cd02156 52 KESIEEDISVCGEDFQQNRELYRW-----VKDNITLPVDPEQVELPRLN------LETTVMSKRK 105
|
|
| nt_trans |
cd02156 |
nucleotidyl transferase superfamily; nt_trans (nucleotidyl transferase) This superfamily ... |
6-78 |
2.02e-03 |
|
nucleotidyl transferase superfamily; nt_trans (nucleotidyl transferase) This superfamily includes the class I amino-acyl tRNA synthetases, pantothenate synthetase (PanC), ATP sulfurylase, and the cytidylyltransferases, all of which have a conserved dinucleotide-binding domain.
Pssm-ID: 173912 [Multi-domain] Cd Length: 105 Bit Score: 37.13 E-value: 2.02e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1689781891 6 VIFSGAQPsGKMTLGNYLGaIKNWTELQDNydCYYSIVDLHAITVPQDPKVLRANAIELLAQYIACGLDPEKN 78
Cdd:cd02156 1 KARFPGEP-GYLHIGHAKL-ICRAKGIADQ--CVVRIDDNPPVKVWQDPHELEERKESIEEDISVCGEDFQQN 69
|
|
| |
