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Conserved domains on  [gi|1691344919|gb|TPE71038|]
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GNAT family N-acetyltransferase [Halalkalibacterium halodurans]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11447364)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
SCOP:  3000403

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
7-172 1.13e-45

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 147.45  E-value: 1.13e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919   7 ILETERLFLREFIGTDIPTLHSLYSDAETMSYYP-APFRYEQTESWVSRNQQRYKRDGYGLWAVCLKETDECIGDCGLVK 85
Cdd:COG1670     2 TLETERLRLRPLRPEDAEALAELLNDPEVARYLPgPPYSLEEARAWLERLLADWADGGALPFAIEDKEDGELIGVVGLYD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  86 QLIEGQThVEIGYHIHKNYWCRGFATEAAKACKSYGFDALGLDKLISIIDPANTASIRVAENIGFTREKEVWIFEKM--- 162
Cdd:COG1670    82 IDRANRS-AEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIdgr 160
                         170
                  ....*....|...
gi 1691344919 163 ---HAIYSGLREE 172
Cdd:COG1670   161 yrdHVLYSLLREE 173
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
7-172 1.13e-45

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 147.45  E-value: 1.13e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919   7 ILETERLFLREFIGTDIPTLHSLYSDAETMSYYP-APFRYEQTESWVSRNQQRYKRDGYGLWAVCLKETDECIGDCGLVK 85
Cdd:COG1670     2 TLETERLRLRPLRPEDAEALAELLNDPEVARYLPgPPYSLEEARAWLERLLADWADGGALPFAIEDKEDGELIGVVGLYD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  86 QLIEGQThVEIGYHIHKNYWCRGFATEAAKACKSYGFDALGLDKLISIIDPANTASIRVAENIGFTREKEVWIFEKM--- 162
Cdd:COG1670    82 IDRANRS-AEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIdgr 160
                         170
                  ....*....|...
gi 1691344919 163 ---HAIYSGLREE 172
Cdd:COG1670   161 yrdHVLYSLLREE 173
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
12-151 4.01e-40

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 132.47  E-value: 4.01e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  12 RLFLREFIGTDIPTLHSLYSDAETMSY-YPAPFRYEQTESWVSRN-QQRYKRDGYGlWAVCLKETDEcIGDCGLVKqLIE 89
Cdd:pfam13302   1 RLLLRPLTEEDAEALFELLSDPEVMRYgVPWPLTLEEAREWLARIwAADEAERGYG-WAIELKDTGF-IGSIGLYD-IDG 77
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1691344919  90 GQTHVEIGYHIHKNYWCRGFATEAAKACKSYGFDALGLDKLISIIDPANTASIRVAENIGFT 151
Cdd:pfam13302  78 EPERAELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
76-156 2.68e-05

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 42.48  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  76 ECIGD-CGLVKQliegqthVEIGyHIHK----------NYWCRGFATEAAKACKSYGFDALGLDKLISIIDPANTASIRV 144
Cdd:PRK15130   63 ECDGEkAGLVEL-------VEIN-HVHRraefqiiispEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHI 134
                          90
                  ....*....|..
gi 1691344919 145 AENIGFTREKEV 156
Cdd:PRK15130  135 YRKLGFEVEGEL 146
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
7-172 1.13e-45

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 147.45  E-value: 1.13e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919   7 ILETERLFLREFIGTDIPTLHSLYSDAETMSYYP-APFRYEQTESWVSRNQQRYKRDGYGLWAVCLKETDECIGDCGLVK 85
Cdd:COG1670     2 TLETERLRLRPLRPEDAEALAELLNDPEVARYLPgPPYSLEEARAWLERLLADWADGGALPFAIEDKEDGELIGVVGLYD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  86 QLIEGQThVEIGYHIHKNYWCRGFATEAAKACKSYGFDALGLDKLISIIDPANTASIRVAENIGFTREKEVWIFEKM--- 162
Cdd:COG1670    82 IDRANRS-AEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVIdgr 160
                         170
                  ....*....|...
gi 1691344919 163 ---HAIYSGLREE 172
Cdd:COG1670   161 yrdHVLYSLLREE 173
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
12-151 4.01e-40

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 132.47  E-value: 4.01e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  12 RLFLREFIGTDIPTLHSLYSDAETMSY-YPAPFRYEQTESWVSRN-QQRYKRDGYGlWAVCLKETDEcIGDCGLVKqLIE 89
Cdd:pfam13302   1 RLLLRPLTEEDAEALFELLSDPEVMRYgVPWPLTLEEAREWLARIwAADEAERGYG-WAIELKDTGF-IGSIGLYD-IDG 77
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1691344919  90 GQTHVEIGYHIHKNYWCRGFATEAAKACKSYGFDALGLDKLISIIDPANTASIRVAENIGFT 151
Cdd:pfam13302  78 EPERAELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
33-150 8.40e-09

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 50.98  E-value: 8.40e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  33 AETMSYYPAPFRYEQTESWVSRNQQRYKRDGYGLWAVclKETDECIGDCGLVKQLIEGQTHVEIGYHIHKNYWCRGFATE 112
Cdd:pfam00583   2 EALYELLSEEFPEPWPDEPLDLLEDWDEDASEGFFVA--EEDGELVGFASLSIIDDEPPVGEIEGLAVAPEYRGKGIGTA 79
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1691344919 113 AAKACKSYGFDaLGLDKLISIIDPANTASIRVAENIGF 150
Cdd:pfam00583  80 LLQALLEWARE-RGCERIFLEVAADNLAAIALYEKLGF 116
COG3981 COG3981
Predicted acetyltransferase [General function prediction only];
96-156 1.43e-08

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443180  Cd Length: 170  Bit Score: 51.45  E-value: 1.43e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1691344919  96 IGYHIHKNYWCRGFATEA-AKACKSYgfDALGLDKLISIIDPANTASIRVAENIGFTREKEV 156
Cdd:COG3981    95 IGYGVRPSERGKGYATEMlRLALEEA--RELGLDRVLITCDKDNIASRKVIEANGGVLEDEV 154
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
15-153 6.01e-06

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 44.22  E-value: 6.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  15 LREFIGTDIPTLHSLYSDA---ETMSYYPAPFRYEQTESWVSRNQQRykrdGYGLWaVCLKEtDECIG--DCGLVKQLIE 89
Cdd:COG1247     4 IRPATPEDAPAIAAIYNEAiaeGTATFETEPPSEEEREAWFAAILAP----GRPVL-VAEED-GEVVGfaSLGPFRPRPA 77
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1691344919  90 GQTHVEIGYHIHKNYWCRGFAT----EAAKACKsygfdALGLDKLISIIDPANTASIRVAENIGFTRE 153
Cdd:COG1247    78 YRGTAEESIYVDPDARGRGIGRalleALIERAR-----ARGYRRLVAVVLADNEASIALYEKLGFEEV 140
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
76-156 2.68e-05

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 42.48  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1691344919  76 ECIGD-CGLVKQliegqthVEIGyHIHK----------NYWCRGFATEAAKACKSYGFDALGLDKLISIIDPANTASIRV 144
Cdd:PRK15130   63 ECDGEkAGLVEL-------VEIN-HVHRraefqiiispEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHI 134
                          90
                  ....*....|..
gi 1691344919 145 AENIGFTREKEV 156
Cdd:PRK15130  135 YRKLGFEVEGEL 146
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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