|
Name |
Accession |
Description |
Interval |
E-value |
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
22-320 |
3.40e-118 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 343.57 E-value: 3.40e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 22 DTHLIRL-ALPGFPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTIIESSSGSTAVSEAYFARLLGLPFIA 100
Cdd:COG0031 13 NTPLVRLnRLSPGPGAEIYAKLESFNPGGSVKDRIALSMIEDAEKRGLLKPGGTIVEATSGNTGIGLAMVAAAKGYRLIL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 101 VMPSCTAKRKIEQIEFYGGRCHFVDNAC---EIYAASEMLAREL-NGHYMDQFTFAERATDWRgnNNIADSIFRQMTHep 176
Cdd:COG0031 93 VMPETMSKERRALLRAYGAEVVLTPGAEgmkGAIDKAEELAAETpGAFWPNQFENPANPEAHY--ETTGPEIWEQTDG-- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 177 ypQPSWIVMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNSVFLdywqsrdaSLRSPVGSKIEGIGRPRVEPSFIPDVVD 256
Cdd:COG0031 169 --KVDAFVAGVGTGGTITGVGRYLKERNPDIKIVAVEPEGSPLL--------SGGEPGPHKIEGIGAGFVPKILDPSLID 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1709425725 257 EMLRVPDAASVATALWLEKQLGRKVGASTGTNMWGVLQLATRMrdeGRQGSIVTLLCDSGERYL 320
Cdd:COG0031 239 EVITVSDEEAFAMARRLAREEGILVGISSGAAVAAALRLAKRL---GPGKTIVTILPDSGERYL 299
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
23-321 |
4.70e-62 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 200.05 E-value: 4.70e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 23 THLIRLA-LPGFPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTIIESSSGSTAVSEAYFARLLGLPFIAV 101
Cdd:cd01561 3 TPLVRLNrLSPGTGAEIYAKLEFFNPGGSVKDRIALYMIEDAEKRGLLKPGTTIIEPTSGNTGIGLAMVAAAKGYRFIIV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 102 MPSCTAKRKIEQIEFYGGRCHFVDNACE------IYAASEMLARELNGHYMDQFtfaERATDWRGN-NNIADSIFRQMTH 174
Cdd:cd01561 83 MPETMSEEKRKLLRALGAEVILTPEAEAdgmkgaIAKARELAAETPNAFWLNQF---ENPANPEAHyETTAPEIWEQLDG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 175 EpypqPSWIVMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNSVFLdywqsrdaSLRSPVGSKIEGIGRPRVEPSFIPDV 254
Cdd:cd01561 160 K----VDAFVAGVGTGGTITGVARYLKEKNPNVRIVGVDPVGSVLF--------SGGPPGPHKIEGIGAGFIPENLDRSL 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1709425725 255 VDEMLRVPDAASVATALWLEKQLGRKVGASTGTNMWGVLQLATRMRDEGRqgsIVTLLCDSGERYLE 321
Cdd:cd01561 228 IDEVVRVSDEEAFAMARRLAREEGLLVGGSSGAAVAAALKLAKRLGPGKT---IVTILPDSGERYLS 291
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
22-314 |
3.34e-49 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 166.72 E-value: 3.34e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 22 DTHLIRL-ALPGFPGIPIYLKDESTHPTGSLKHRLARSLFLYgLCNGwiKEGTTIIESSSGSTAVSEAYFARLLGLPFIA 100
Cdd:pfam00291 7 PTPLVRLpRLSKELGVDVYLKLESLNPTGSFKDRGALNLLLR-LKEG--EGGKTVVEASSGNHGRALAAAAARLGLKVTI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 101 VMPSCTAKRKIEQIEFYGGRCHFVD-NACEIYAASEMLARELNG-HYMDQFtfaERATDWRGNNNIADSIFRQMThepyP 178
Cdd:pfam00291 84 VVPEDAPPGKLLLMRALGAEVVLVGgDYDEAVAAARELAAEGPGaYYINQY---DNPLNIEGYGTIGLEILEQLG----G 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 179 QPSWIVMSAGTGGTSATIGRYIRCQGYETQLMVVDP-QNSVFLDYWQSRDASLRSPVGSKIEGIGRPRVEPSFIPDV--- 254
Cdd:pfam00291 157 DPDAVVVPVGGGGLIAGIARGLKELGPDVRVIGVEPeGAPALARSLAAGRPVPVPVADTIADGLGVGDEPGALALDLlde 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1709425725 255 -VDEMLRVPDAASVATALWLEKQLGRKVGASTGTNMWGV-LQLATRMRDEGRqgsIVTLLCD 314
Cdd:pfam00291 237 yVGEVVTVSDEEALEAMRLLARREGIVVEPSSAAALAALkLALAGELKGGDR---VVVVLTG 295
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
23-331 |
3.66e-37 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 136.14 E-value: 3.66e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 23 THLIRLALPG-FPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTIIESSSGSTAVSEAYFARLLGLPFIAV 101
Cdd:PRK10717 14 TPLIRLNRASeATGCEILGKAEFLNPGGSVKDRAALNIIWDAEKRGLLKPGGTIVEGTAGNTGIGLALVAAARGYKTVIV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 102 MPSCTAKRKIEQIEFYGGRCHFVDnACEiYA------------ASEMLARELNGHYM-DQFtfaeratdwrgnNNIADS- 167
Cdd:PRK10717 94 MPETQSQEKKDLLRALGAELVLVP-AAP-YAnpnnyvkgagrlAEELVASEPNGAIWaNQF------------DNPANRe 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 168 ---------IFRQMTHEpypqpswI---VMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNSVFLDYWQSRDasLRSPVG 235
Cdd:PRK10717 160 ahyettgpeIWEQTDGK-------VdgfVCAVGTGGTLAGVSRYLKETNPKVKIVLADPTGSALYSYYKTGE--LKAEGS 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 236 SKIEGIGRPRVEPSFIPDVVDEMLRVPDAASVATALWLEKQLGRKVGASTGTNMWGVLQLAtrmRDEGRQGSIVTLLCDS 315
Cdd:PRK10717 231 SITEGIGQGRITANLEGAPIDDAIRIPDEEALSTAYRLLEEEGLCLGGSSGINVAAALRLA---RELGPGHTIVTILCDS 307
|
330
....*....|....*.
gi 1709425725 316 GERYLESYYNPQWVAA 331
Cdd:PRK10717 308 GERYQSKLFNPDFLRE 323
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
23-315 |
1.60e-34 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 126.86 E-value: 1.60e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 23 THLIRLA-LPGFPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKeGTTIIESSSGSTAVSEAYFARLLGLPFIAV 101
Cdd:cd00640 1 TPLVRLKrLSKLGGANIYLKLEFLNPTGSFKDRGALNLILLAEEEGKLP-KGVIIESTGGNTGIALAAAAARLGLKCTIV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 102 MPSCTAKRKIEQIEFYGGRCHFVD---NACeIYAASEMLARELNGHYMDQFTFAERatdWRGNNNIADSIFRQMTHEPyp 178
Cdd:cd00640 80 MPEGASPEKVAQMRALGAEVVLVPgdfDDA-IALAKELAEEDPGAYYVNQFDNPAN---IAGQGTIGLEILEQLGGQK-- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 179 qPSWIVMSAGTGGTSATIGRYIRCQGYETQLMVVDPqnsvfldywqsrdaslrspvgskiegigrprvepsfipdvvdEM 258
Cdd:cd00640 154 -PDAVVVPVGGGGNIAGIARALKELLPNVKVIGVEP------------------------------------------EV 190
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 1709425725 259 LRVPDAASVATALWLEKQLGRKVGASTGTNMWGVLQLAtrmRDEGRQGSIVTLLCDS 315
Cdd:cd00640 191 VTVSDEEALEAIRLLAREEGILVEPSSAAALAAALKLA---KKLGKGKTVVVILTGG 244
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
23-322 |
2.34e-22 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 95.33 E-value: 2.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 23 THLIRLA-LPGFPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTIIESSSGSTAVSEAYFARLLGLPFIAV 101
Cdd:PRK11761 13 TPLVKLQrLPPDRGNTILAKLEGNNPAGSVKDRPALSMIVQAEKRGEIKPGDTLIEATSGNTGIALAMIAAIKGYRMKLI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 102 MP-SCTAKRKiEQIEFYGGRCHFVDNACEIYAA---SEMLARELNGHYMDQFTfaeRATDWRGN-NNIADSIFRQ----M 172
Cdd:PRK11761 93 MPeNMSQERR-AAMRAYGAELILVPKEQGMEGArdlALQMQAEGEGKVLDQFA---NPDNPLAHyETTGPEIWRQtegrI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 173 THepypqpswIVMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNsvfldywqsrdaslrspvGSKIEGIGR------PRV 246
Cdd:PRK11761 169 TH--------FVSSMGTTGTIMGVSRYLKEQNPAVQIVGLQPEE------------------GSSIPGIRRwpeeylPKI 222
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709425725 247 epsFIPDVVDEMLRVPDAASVATALWLEKQLGRKVGASTGTNMWGVLQLATRMRDegrqGSIVTLLCDSGERYLES 322
Cdd:PRK11761 223 ---FDASRVDRVLDVSQQEAENTMRRLAREEGIFCGVSSGGAVAAALRIARENPN----AVIVAIICDRGDRYLST 291
|
|
| PLN02356 |
PLN02356 |
phosphateglycerate kinase |
22-330 |
1.00e-21 |
|
phosphateglycerate kinase
Pssm-ID: 215204 Cd Length: 423 Bit Score: 95.44 E-value: 1.00e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 22 DTHLIRL-ALPGFPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTIIESSSGSTAVSEAYFARLLGLPFIA 100
Cdd:PLN02356 53 NTPLIRInSLSEATGCEILGKCEFLNPGGSVKDRVAVKIIEEALESGQLFPGGVVTEGSAGSTAISLATVAPAYGCKCHV 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 101 VMPSCTAKRKIEQIEFYGG------------RCHFVDNACEIYAASEMLAREL--------------NGHYMDQFTFAER 154
Cdd:PLN02356 133 VIPDDVAIEKSQILEALGAtvervrpvsithKDHYVNIARRRALEANELASKRrkgsetdgihlektNGCISEEEKENSL 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 155 ATDWRGNNNIADSI-----FR--------QMTHEPYPQPSWIVMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNS---- 217
Cdd:PLN02356 213 FSSSCTGGFFADQFenlanFRahyegtgpEIWEQTQGNLDAFVAAAGTGGTLAGVSRFLQEKNPNIKCFLIDPPGSglfn 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 218 -----VFLDYWQSRDASLRSPVGSKIEGIGRPRVEPSFIPDVVDEMLRVPDAASVATALWLEKQLGRKVGASTGTNMWGV 292
Cdd:PLN02356 293 kvtrgVMYTREEAEGRRLKNPFDTITEGIGINRLTQNFLMAKLDGAFRGTDKEAVEMSRYLLKNDGLFVGSSSAMNCVGA 372
|
330 340 350
....*....|....*....|....*....|....*...
gi 1709425725 293 LQLATRMrdeGRQGSIVTLLCDSGERYLESYYNPQWVA 330
Cdd:PLN02356 373 VRVAQSL---GPGHTIVTILCDSGMRHLSKFHDPQYLS 407
|
|
| PLN02565 |
PLN02565 |
cysteine synthase |
38-322 |
2.33e-20 |
|
cysteine synthase
Pssm-ID: 166206 Cd Length: 322 Bit Score: 90.37 E-value: 2.33e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 38 IYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTI-IESSSGSTAVSEAYFARLLGLPFIAVMP-SCTAKRKIEQIE 115
Cdd:PLN02565 32 IAAKLEMMEPCSSVKDRIGYSMITDAEEKGLIKPGESVlIEPTSGNTGIGLAFMAAAKGYKLIITMPaSMSLERRIILLA 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 116 FyGGRCHFVDNA----CEIYAASEMLARELNGHYMDQFtfaERATD------------WRGNNNIADSIfrqmthepypq 179
Cdd:PLN02565 112 F-GAELVLTDPAkgmkGAVQKAEEILAKTPNSYILQQF---ENPANpkihyettgpeiWKGTGGKVDAF----------- 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 180 pswiVMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNSVFLdywqsrdaSLRSPVGSKIEGIGrprvePSFIP-----DV 254
Cdd:PLN02565 177 ----VSGIGTGGTITGAGKYLKEQNPDIKLYGVEPVESAVL--------SGGKPGPHKIQGIG-----AGFIPgvldvDL 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1709425725 255 VDEMLRVPDAASVATALWLEKQLGRKVGASTGTNMWGVLQLATRMRDEGRQgsIVTLLCDSGERYLES 322
Cdd:PLN02565 240 LDEVVQVSSDEAIETAKLLALKEGLLVGISSGAAAAAAIKIAKRPENAGKL--IVVIFPSFGERYLSS 305
|
|
| PLN00011 |
PLN00011 |
cysteine synthase |
38-322 |
2.52e-19 |
|
cysteine synthase
Pssm-ID: 177651 Cd Length: 323 Bit Score: 87.37 E-value: 2.52e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 38 IYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEG-TTIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTA-KRKIeQIE 115
Cdd:PLN00011 34 IAAKLEMMEPCSSVKDRIAYSMIKDAEDKGLITPGkSTLIEATAGNTGIGLACIGAARGYKVILVMPSTMSlERRI-ILR 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 116 FYGGRCHFVDNAC----EIYAASEMLARELNGHYMDQFTFAERA-TDWRgnnNIADSIFRQMTHEPypqpSWIVMSAGTG 190
Cdd:PLN00011 113 ALGAEVHLTDQSIglkgMLEKAEEILSKTPGGYIPQQFENPANPeIHYR---TTGPEIWRDSAGKV----DILVAGVGTG 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 191 GTSATIGRYIRCQGYETQLMVVDPQNSVFLdywqsrdaSLRSPVGSKIEGIGRPRVEPSFIPDVVDEMLRVPDAASVATA 270
Cdd:PLN00011 186 GTATGVGKFLKEKNKDIKVCVVEPVESAVL--------SGGQPGPHLIQGIGSGIIPFNLDLTIVDEIIQVTGEEAIETA 257
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1709425725 271 LWLEKQLGRKVGASTGTNMWGVLQLATRMRDEGRQgsIVTLLCDSGERYLES 322
Cdd:PLN00011 258 KLLALKEGLLVGISSGAAAAAALKVAKRPENAGKL--IVVIFPSGGERYLST 307
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
35-322 |
8.34e-19 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 86.17 E-value: 8.34e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEG-TTIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQ 113
Cdd:PLN02556 73 GAYIAAKQEMFQPTSSIKDRPALAMIEDAEKKNLITPGkTTLIEPTSGNMGISLAFMAAMKGYKMILTMPSYTSLERRVT 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 114 IEFYGGRCHFVDNA----CEIYAASEMLARELNGHYMDQFtfaeratdwrgnNNIADSIFRQMTHEP------YPQPSWI 183
Cdd:PLN02556 153 MRAFGAELVLTDPTkgmgGTVKKAYELLESTPDAFMLQQF------------SNPANTQVHFETTGPeiwedtLGQVDIF 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 184 VMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNSVFLDYWQsrdaslrsPVGSKIEGIGrprvePSFIPDVVD-----EM 258
Cdd:PLN02556 221 VMGIGSGGTVSGVGKYLKSKNPNVKIYGVEPAESNVLNGGK--------PGPHHITGNG-----VGFKPDILDmdvmeKV 287
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1709425725 259 LRVP--DAASVATALWLEKqlGRKVGASTGTNMWGVLQLATRMRDEGRQgsIVTLLCDSGERYLES 322
Cdd:PLN02556 288 LEVSseDAVNMARELALKE--GLMVGISSGANTVAALRLAKMPENKGKL--IVTVHPSFGERYLSS 349
|
|
| PLN03013 |
PLN03013 |
cysteine synthase |
38-322 |
7.96e-16 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 77.89 E-value: 7.96e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 38 IYLKDESTHPTGSLKHRLARSLFLYGLCNGWIKEGTTI-IESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQIEF 116
Cdd:PLN03013 140 IAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVlVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKA 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 117 YGGRCHFVDNA----CEIYAASEMLARELNGHYMDQFtfaeratDWRGNNNIA-DSIFRQMTHEPYPQPSWIVMSAGTGG 191
Cdd:PLN03013 220 FGAELVLTDPAkgmtGAVQKAEEILKNTPDAYMLQQF-------DNPANPKIHyETTGPEIWDDTKGKVDIFVAGIGTGG 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 192 TSATIGRYIRCQGYETQLMVVDPQNSVFLdywqsrdaSLRSPVGSKIEGIGRPRVEPSFIPDVVDEMLRVPDAASVATAL 271
Cdd:PLN03013 293 TITGVGRFIKEKNPKTQVIGVEPTESDIL--------SGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEAIETAK 364
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 1709425725 272 WLEKQLGRKVGASTGTNMWGVLQLATRMRDEGRqgsIVTLLCDSGERYLES 322
Cdd:PLN03013 365 QLALKEGLMVGISSGAAAAAAIKVAKRPENAGK---LIAVSLFASGRDIYT 412
|
|
| L-Ser-dehyd |
cd06448 |
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
23-191 |
9.29e-13 |
|
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.
Pssm-ID: 107209 Cd Length: 316 Bit Score: 68.09 E-value: 9.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 23 THLIR-LALPGFPGIPIYLKDESTHPTGSLKHRlarslflyG---LCNGWIKEGTT----IIESSSGSTAVSEAYFARLL 94
Cdd:cd06448 2 TPLIEsTALSKTAGCNVFLKLENLQPSGSFKIR--------GighLCQKSAKQGLNecvhVVCSSGGNAGLAAAYAARKL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 95 GLPFIAVMPSCTAKRKIEQIEFYGGRCHF---VDNACEIYAASEMLARELNGHYMDQFtfaERATDWRGNNNIADSIFRQ 171
Cdd:cd06448 74 GVPCTIVVPESTKPRVVEKLRDEGATVVVhgkVWWEADNYLREELAENDPGPVYVHPF---DDPLIWEGHSSMVDEIAQQ 150
|
170 180
....*....|....*....|
gi 1709425725 172 MthEPYPQPSWIVMSAGTGG 191
Cdd:cd06448 151 L--QSQEKVDAIVCSVGGGG 168
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
35-273 |
5.50e-12 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 65.59 E-value: 5.50e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRLARSLFLyGLCNGWIKEGttIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQI 114
Cdd:cd01562 31 GAEVYLKCENLQKTGSFKIRGAYNKLL-SLSEEERAKG--VVAASAGNHAQGVAYAAKLLGIPATIVMPETAPAAKVDAT 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 115 EFYGGRCHFVDnacEIYAASEMLAREL---NG----H-YMDQFTFAERATdwrgnnnIADSIFRQMthepyPQPSWIVMS 186
Cdd:cd01562 108 RAYGAEVVLYG---EDFDEAEAKARELaeeEGltfiHpFDDPDVIAGQGT-------IGLEILEQV-----PDLDAVFVP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 187 AGTGGTSATIGRYIRCQGYETQLMVVDPQNSVflDYWQSRDASLRS--PVGSKI-EGIGRPRVEP---SFIPDVVDEMLR 260
Cdd:cd01562 173 VGGGGLIAGIATAVKALSPNTKVIGVEPEGAP--AMAQSLAAGKPVtlPEVDTIaDGLAVKRPGEltfEIIRKLVDDVVT 250
|
250
....*....|...
gi 1709425725 261 VPDAASVATALWL 273
Cdd:cd01562 251 VSEDEIAAAMLLL 263
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
13-196 |
3.66e-10 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 60.10 E-value: 3.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 13 INADYQRSADTHLIRL-ALPGFPGI-PIYLKDESTHPTGSLKHRLARSLFLYGLCNGWikegTTIIESSSGSTAVSEAYF 90
Cdd:PRK06381 6 SSSEEKPPGGTPLLRArKLEEELGLrKIYLKFEGANPTGTQKDRIAEAHVRRAMRLGY----SGITVGTCGNYGASIAYF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 91 ARLLGLPFIAVMPSCTAKRKIEQIEFYGGRCHFVDNACE-IYAASEMLARElNGHYMDQFTFAERATDWRGNNNIADSIF 169
Cdd:PRK06381 82 ARLYGLKAVIFIPRSYSNSRVKEMEKYGAEIIYVDGKYEeAVERSRKFAKE-NGIYDANPGSVNSVVDIEAYSAIAYEIY 160
|
170 180
....*....|....*....|....*..
gi 1709425725 170 RQMTHEPYpqpsWIVMSAGTGGTSATI 196
Cdd:PRK06381 161 EALGDVPD----AVAVPVGNGTTLAGI 183
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
35-321 |
9.37e-10 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 58.94 E-value: 9.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRLARSLFLygLCNGWIKEgTTIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQI 114
Cdd:PRK06815 34 GCEVYLKCEHLQHTGSFKFRGASNKLR--LLNEAQRQ-QGVITASSGNHGQGVALAAKLAGIPVTVYAPEQASAIKLDAI 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 115 EFYGGRCHFVDNAC---EIYAASemlARELNGH-----YMDQFTFAeratdwrGNNNIADSIFRQMthepyPQPSWIVMS 186
Cdd:PRK06815 111 RALGAEVRLYGGDAlnaELAARR---AAEQQGKvyispYNDPQVIA-------GQGTIGMELVEQQ-----PDLDAVFVA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 187 AGTGGTSATIGRYIRCQGYETQLMVVDPQNSVFLdyWQSRDAslrspvGSKIEGIGRPR--------VEPSFIP-----D 253
Cdd:PRK06815 176 VGGGGLISGIATYLKTLSPKTEIIGCWPANSPSL--YTSLEA------GEIVEVAEQPTlsdgtaggVEPGAITfplcqQ 247
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1709425725 254 VVDEMLRVP-DAASVATALWLEKQLGRKVGAStGTNMWGVLQLATRMRdeGRQGSIVtlLCD---SGERYLE 321
Cdd:PRK06815 248 LIDQKVLVSeEEIKEAMRLIAETDRWLIEGAA-GVALAAALKLAPRYQ--GKKVAVV--LCGkniVLEKYLE 314
|
|
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
23-125 |
1.88e-09 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 57.99 E-value: 1.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 23 THLIRL-ALPGFPGIP-IYLKDESTHPTGSLKHRLARSLFLYGLCNGwIKegtTIIESSSGSTAVSEAYFARLLGLPFIA 100
Cdd:cd01563 23 TPLVRApRLGERLGGKnLYVKDEGLNPTGSFKDRGMTVAVSKAKELG-VK---AVACASTGNTSASLAAYAARAGIKCVV 98
|
90 100
....*....|....*....|....*
gi 1709425725 101 VMPSCTAKRKIEQIEFYGGRCHFVD 125
Cdd:cd01563 99 FLPAGKALGKLAQALAYGATVLAVE 123
|
|
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
35-273 |
2.13e-09 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 58.12 E-value: 2.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLK-----HRLARslflyglCNGWIKEgTTIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKR 109
Cdd:COG1171 38 GAEVYLKLENLQPTGSFKlrgayNALAS-------LSEEERA-RGVVAASAGNHAQGVAYAARLLGIPATIVMPETAPAV 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 110 KIEQIEFYGGRCHFVDnacEIYAASEMLARELnghymdqftfaERATDWR------------GNNNIADSIFRQMthepy 177
Cdd:COG1171 110 KVAATRAYGAEVVLHG---DTYDDAEAAAAEL-----------AEEEGATfvhpfddpdviaGQGTIALEILEQL----- 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 178 PQPSWIVMSAGTGGTSATIGRYIRCQGYETQLMVVDPQNSVflDYWQSRDAS--LRSPVGSKI-EGIGRPRVEP---SFI 251
Cdd:COG1171 171 PDLDAVFVPVGGGGLIAGVAAALKALSPDIRVIGVEPEGAA--AMYRSLAAGepVTLPGVDTIaDGLAVGRPGEltfEIL 248
|
250 260
....*....|....*....|..
gi 1709425725 252 PDVVDEMLRVPDAASVATALWL 273
Cdd:COG1171 249 RDLVDDIVTVSEDEIAAAMRLL 270
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
6-196 |
3.79e-09 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 57.90 E-value: 3.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 6 VKHAISeinadyQRSADTHLIRLALPGFPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGwikeGTTIIESSSGSTAV 85
Cdd:PRK05638 56 VKKIIS------LGEGGTPLIRARISEKLGENVYIKDETRNPTGSFRDRLATVAVSYGLPYA----ANGFIVASDGNAAA 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 86 SEAYFARLLGLPFIAVMPSCTAKRKIEQIEFYGGRC----HFVDNACEiYAasEMLAReLNGHYmdQFTFAERATDWRGN 161
Cdd:PRK05638 126 SVAAYSARAGKEAFVVVPRKVDKGKLIQMIAFGAKIirygESVDEAIE-YA--EELAR-LNGLY--NVTPEYNIIGLEGQ 199
|
170 180 190
....*....|....*....|....*....|....*
gi 1709425725 162 NNIADSIFRQMthepypQPSWIVMSAGTGGTSATI 196
Cdd:PRK05638 200 KTIAFELWEEI------NPTHVIVPTGSGSYLYSI 228
|
|
| PRK08639 |
PRK08639 |
threonine dehydratase; Validated |
38-215 |
2.73e-08 |
|
threonine dehydratase; Validated
Pssm-ID: 236318 [Multi-domain] Cd Length: 420 Bit Score: 54.81 E-value: 2.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 38 IYLKDESTHPTGSLKHRLA----RSLFLYGLCNGwikegttIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQ 113
Cdd:PRK08639 42 VYLKREDLQPVRSYKLRGAynaiSQLSDEELAAG-------VVCASAGNHAQGVAYACRHLGIPGVIFMPVTTPQQKIDQ 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 114 IEFYGGRchFV------DNACEIYAASEMLARELNGHYMDQF----TFAERATdwrgnnnIADSIFRQMTHEpyPQPSWI 183
Cdd:PRK08639 115 VRFFGGE--FVeivlvgDTFDDSAAAAQEYAEETGATFIPPFddpdVIAGQGT-------VAVEILEQLEKE--GSPDYV 183
|
170 180 190
....*....|....*....|....*....|..
gi 1709425725 184 VMSAGTGGTSATIGRYIRCQGYETQLMVVDPQ 215
Cdd:PRK08639 184 FVPVGGGGLISGVTTYLKERSPKTKIIGVEPA 215
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
38-119 |
9.44e-08 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 53.24 E-value: 9.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 38 IYLKDESTHPTGSLKHRlarslflyGLCNG--WIKEG----TTIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKI 111
Cdd:PRK06608 40 IFFKVESLQKTGAFKVR--------GVLNHllELKEQgklpDKIVAYSTGNHGQAVAYASKLFGIKTRIYLPLNTSKVKQ 111
|
....*...
gi 1709425725 112 EQIEFYGG 119
Cdd:PRK06608 112 QAALYYGG 119
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
35-125 |
5.99e-07 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 50.58 E-value: 5.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGWIkegtTIIESSSGSTAVSEAYFARLLGLPFIAVMPS-CTAKRKIEQ 113
Cdd:COG0498 80 GKNLYVKEEGHNPTGSFKDRAMQVAVSLALERGAK----TIVCASSGNGSAALAAYAARAGIEVFVFVPEgKVSPGQLAQ 155
|
90
....*....|..
gi 1709425725 114 IEFYGGRCHFVD 125
Cdd:COG0498 156 MLTYGAHVIAVD 167
|
|
| PRK08813 |
PRK08813 |
threonine dehydratase; Provisional |
38-305 |
5.97e-06 |
|
threonine dehydratase; Provisional
Pssm-ID: 236339 [Multi-domain] Cd Length: 349 Bit Score: 47.70 E-value: 5.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 38 IYLKDESTHPTGSLKHRLARSLFLYGLCNGwikEGTTIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQIEFY 117
Cdd:PRK08813 50 VWLKLENLQRTGSYKVRGALNALLAGLERG---DERPVICASAGNHAQGVAWSAYRLGVQAITVMPHGAPQTKIAGVAHW 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 118 GGRCHFVDNAC-EIYAASEMLARELNGHYMDQFtfaeratdwrgnnNIADSIFRQMT-------HEpypqPSWIVMSAGT 189
Cdd:PRK08813 127 GATVRQHGNSYdEAYAFARELADQNGYRFLSAF-------------DDPDVIAGQGTvgielaaHA----PDVVIVPIGG 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 190 GGTSATIGRYIRCQGYE---TQLMVVDPQ-NSVFLDYWQ-SRDASLRSPVGSKIEGIGRPRVEPSFIPDVVdeMLRVPDA 264
Cdd:PRK08813 190 GGLASGVALALKSQGVRvvgAQVEGVDSMaRAIRGDLREiAPVATLADGVKVKIPGFLTRRLCSSLLDDVV--IVREAEL 267
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 1709425725 265 ASVATALWLEKQLGRKvGAstgtnmwGVLQLATRMRDEGRQ 305
Cdd:PRK08813 268 RETLVRLALEEHVIAE-GA-------GALALAAGRRVSGKR 300
|
|
| PRK06450 |
PRK06450 |
threonine synthase; Validated |
31-189 |
1.00e-05 |
|
threonine synthase; Validated
Pssm-ID: 180565 [Multi-domain] Cd Length: 338 Bit Score: 46.65 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 31 PGFPGIPIYLKDESTHPTGSLKHRLARSLFLYGLCNGwIKEgttIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRK 110
Cdd:PRK06450 60 PLIKKGNIWFKLDFLNPTGSYKDRGSVTLISYLAEKG-IKQ---ISEDSSGNAGASIAAYGAAAGIEVKIFVPETASGGK 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 111 IEQIEFYGGRCHFVDNACE-IYAASEMLARELNGH-YMDQFtfaeratdWRGNNNIADSIFRQMTHEPyPQPSWIVMSAG 188
Cdd:PRK06450 136 LKQIESYGAEVVRVRGSREdVAKAAENSGYYYASHvLQPQF--------RDGIRTLAYEIAKDLDWKI-PNYVFIPVSAG 206
|
.
gi 1709425725 189 T 189
Cdd:PRK06450 207 T 207
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
35-217 |
2.22e-04 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 42.86 E-value: 2.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRLARSLfLYGLCNGWIKEGttIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQI 114
Cdd:PRK12483 51 GNQVLLKREDLQPVFSFKIRGAYNK-MARLPAEQLARG--VITASAGNHAQGVALAAARLGVKAVIVMPRTTPQLKVDGV 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 115 EFYGGRchfVDNACEIYaaSEMLARELNGHYMDQFTFAERATD---WRGNNNIADSIFRQmthepYPQP-SWIVMSAGTG 190
Cdd:PRK12483 128 RAHGGE---VVLHGESF--PDALAHALKLAEEEGLTFVPPFDDpdvIAGQGTVAMEILRQ-----HPGPlDAIFVPVGGG 197
|
170 180
....*....|....*....|....*..
gi 1709425725 191 GTSATIGRYIRCQGYETQLMVVDPQNS 217
Cdd:PRK12483 198 GLIAGIAAYVKYVRPEIKVIGVEPDDS 224
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
35-217 |
9.97e-04 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 41.06 E-value: 9.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRLARSLfLYGLCNGWIKEGttIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQI 114
Cdd:PLN02550 123 GVKVLLKREDLQPVFSFKLRGAYNM-MAKLPKEQLDKG--VICSSAGNHAQGVALSAQRLGCDAVIAMPVTTPEIKWQSV 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 115 EFYGGRCHFV-DNACEIYAASEMLARELNGHYMDQFTFAERATdwrGNNNIADSIFRQMthePYPQPSwIVMSAGTGGTS 193
Cdd:PLN02550 200 ERLGATVVLVgDSYDEAQAYAKQRALEEGRTFIPPFDHPDVIA---GQGTVGMEIVRQH---QGPLHA-IFVPVGGGGLI 272
|
170 180
....*....|....*....|....
gi 1709425725 194 ATIGRYIRCQGYETQLMVVDPQNS 217
Cdd:PLN02550 273 AGIAAYVKRVRPEVKIIGVEPSDA 296
|
|
| PRK07334 |
PRK07334 |
threonine dehydratase; Provisional |
35-141 |
1.05e-03 |
|
threonine dehydratase; Provisional
Pssm-ID: 235994 [Multi-domain] Cd Length: 403 Bit Score: 40.65 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRlarslflyGLCNGWI-------KEGttIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTA 107
Cdd:PRK07334 37 GAEVWLKFENLQFTASFKER--------GALNKLLllteeerARG--VIAMSAGNHAQGVAYHAQRLGIPATIVMPRFTP 106
|
90 100 110
....*....|....*....|....*....|....
gi 1709425725 108 KRKIEQIEFYGGRchfVDNACEIYAASEMLAREL 141
Cdd:PRK07334 107 TVKVERTRGFGAE---VVLHGETLDEARAHAREL 137
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
35-199 |
1.06e-03 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 40.58 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 35 GIPIYLKDESTHPTGSLKHRlARSLFLYGLCNGWIKEgttIIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQI 114
Cdd:PRK08329 71 SIKVYFKLDYLQPTGSFKDR-GTYVTVAKLKEEGINE---VVIDSSGNAALSLALYSLSEGIKVHVFVSYNASKEKISLL 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 115 EFYGGRCHFVD-NACEIYAASEMLARELN----GHYMDQFtFAEratdwrGNNNIADSIFRQMThepypQPSWIVMSAGT 189
Cdd:PRK08329 147 SRLGAELHFVEgDRMEVHEEAVKFSKRNNipyvSHWLNPY-FLE------GTKTIAYEIYEQIG-----VPDYAFVPVGS 214
|
170
....*....|
gi 1709425725 190 GgtSATIGRY 199
Cdd:PRK08329 215 G--TLFLGIW 222
|
|
| PLN02970 |
PLN02970 |
serine racemase |
7-129 |
1.75e-03 |
|
serine racemase
Pssm-ID: 215524 [Multi-domain] Cd Length: 328 Bit Score: 39.66 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1709425725 7 KHA--ISEINADYQRSADT-H----LIRLALPGFPGIPIYLKDESTHPTGSLKHRlarslflyGLCNG---WIKEGTT-- 74
Cdd:PLN02970 6 KYAadLSSIREARKRIAPFiHrtpvLTSSSLDALAGRSLFFKCECFQKGGAFKFR--------GACNAifsLSDDQAEkg 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 1709425725 75 IIESSSGSTAVSEAYFARLLGLPFIAVMPSCTAKRKIEQIEFYGGRCHFVDNACE 129
Cdd:PLN02970 78 VVTHSSGNHAAALALAAKLRGIPAYIVVPKNAPACKVDAVIRYGGIITWCEPTVE 132
|
|
| |
