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Conserved domains on  [gi|1709643882|gb|TSO27076|]
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hypothetical protein FOD82_06080 [Lactobacillus sp. LL6]

Protein Classification

type II toxin-antitoxin system RelE/ParE family toxin( domain architecture ID 229520)

type II toxin-antitoxin (TA) system RelE/ParE family toxin similar to Escherichia coli ParE, the toxin component of a TA module involved in involved in plasmid partition; acts by inhibiting DNA gyrase, converting supercoiled plasmid DNA into a singly cleaved linear form in an ATP-dependent fashion

Gene Ontology:  GO:0008657|GO:0042803|GO:0051290|GO:0030541
PubMed:  20143871|26478181|20487277

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gp49 super family cl46407
Phage derived protein Gp49-like (DUF891); This family consists of hypothetical bacterial ...
 2-34 4.60e-07

Phage derived protein Gp49-like (DUF891); This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.


The actual alignment was detected with superfamily member COG4679:

Pssm-ID: 480747  Cd Length: 113  Bit Score: 41.76  E-value: 4.60e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1709643882   2 ITNGFTKKTKKTPVREINHAKELRKEYYDNKKK 34
Cdd:COG4679    81 VLHGFQKKTQKTPKKEIELARKRLKEYLEEKKE 113
 
Name Accession Description Interval E-value
COG4679 COG4679
Phage-related protein [Mobilome: prophages, transposons];
2-34 4.60e-07

Phage-related protein [Mobilome: prophages, transposons];


Pssm-ID: 443715  Cd Length: 113  Bit Score: 41.76  E-value: 4.60e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1709643882   2 ITNGFTKKTKKTPVREINHAKELRKEYYDNKKK 34
Cdd:COG4679    81 VLHGFQKKTQKTPKKEIELARKRLKEYLEEKKE 113
Gp49 pfam05973
Phage derived protein Gp49-like (DUF891); This family consists of hypothetical bacterial ...
 2-26 1.34e-03

Phage derived protein Gp49-like (DUF891); This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.


Pssm-ID: 461791  Cd Length: 90  Bit Score: 32.17  E-value: 1.34e-03
                         10        20
                 ....*....|....*....|....*
gi 1709643882  2 ITNGFTKKTKKTPVREINHAKELRK 26
Cdd:pfam05973 66 VLHAFQKKTQKTPKKEIDLAERRLK 90
 
Name Accession Description Interval E-value
COG4679 COG4679
Phage-related protein [Mobilome: prophages, transposons];
2-34 4.60e-07

Phage-related protein [Mobilome: prophages, transposons];


Pssm-ID: 443715  Cd Length: 113  Bit Score: 41.76  E-value: 4.60e-07
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1709643882   2 ITNGFTKKTKKTPVREINHAKELRKEYYDNKKK 34
Cdd:COG4679    81 VLHGFQKKTQKTPKKEIELARKRLKEYLEEKKE 113
Gp49 pfam05973
Phage derived protein Gp49-like (DUF891); This family consists of hypothetical bacterial ...
 2-26 1.34e-03

Phage derived protein Gp49-like (DUF891); This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.


Pssm-ID: 461791  Cd Length: 90  Bit Score: 32.17  E-value: 1.34e-03
                         10        20
                 ....*....|....*....|....*
gi 1709643882  2 ITNGFTKKTKKTPVREINHAKELRK 26
Cdd:pfam05973 66 VLHAFQKKTQKTPKKEIDLAERRLK 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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