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Conserved domains on  [gi|1730616595|gb|TYF92864|]
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glycerone kinase [Klebsiella grimontii]

Protein Classification

dihydroxyacetone kinase family protein( domain architecture ID 1001500)

dihydroxyacetone kinase family protein similar to human triokinase/FMN cyclase and dihydroxyacetone kinase subunit L (DhaL), which is the ADP-binding subunit of dihydroxyacetone kinase that catalyzes the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP

Gene Ontology:  GO:0004371|GO:0006071|GO:0005524
PubMed:  16505971|15476397

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK14479 super family cl29418
dihydroxyacetone kinase; Provisional
3-547 0e+00

dihydroxyacetone kinase; Provisional


The actual alignment was detected with superfamily member TIGR02361:

Pssm-ID: 475197 [Multi-domain]  Cd Length: 574  Bit Score: 600.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   3 QFFFNQRANLVNDVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 158 VHKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 237 VTLMAEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELAHTPLQ-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 307 AIVLEE---SIEKALLSAVETAGW----QTPVQPREIS---VMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKRevvSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHL 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554
                         570       580
                  ....*....|....*....|
gi 1730616595 528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
3-547 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 600.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   3 QFFFNQRANLVNDVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 158 VHKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 237 VTLMAEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELAHTPLQ-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 307 AIVLEE---SIEKALLSAVETAGW----QTPVQPREIS---VMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKRevvSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHL 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554
                         570       580
                  ....*....|....*....|
gi 1730616595 528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
1-547 1.13e-129

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 390.71  E-value: 1.13e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   1 MSQFFFNQRANLVNDVIEGTIIASPwNNLARLESdpaIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCG 80
Cdd:PTZ00375    2 VSKKFINSPEKVVSEAVDGLCMTNN-DSLKRIEN---TNVVVRSDIDKTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCG 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  81 DLFASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDIS--LPDNKHPRGIAGTILV 158
Cdd:PTZ00375   78 SVFASPSTKHVLAAIEYVPNGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAfgTKDIANRRGIAGTVLL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 159 HKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDaETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVT 238
Cdd:PTZ00375  158 YKILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGN-DPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVK 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 239 LMAEKL-----------SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRIDWL-IGPASLVTALDMKGFSLT 306
Cdd:PTZ00375  237 FLIGILlgkgkkrgggkTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQLAQAGLTVVgVHSGRLMTSLEMHGFSLT 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 307 AIVLEESIEKALLSAVETA---------GWQTPVQPRE-ISVMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:PTZ00375  317 LLPIEDEDDLQLLDTNQKPllnfhtpqsSWATAKGPLSaLQLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENYL 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 377 NALDAKVGDGDTGSTFAAGARDIADLLQrRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGA----- 451
Cdd:PTZ00375  397 NELDAEVGDGDLGSGLERSSKAVLESLP-YLPLEANVRKTLTLISKAVADAFGGSSGPLYGAFLLGGANALAEALnggna 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 452 --SVAEALNAGLAQMKFYGGADEGDRTMIDALQPAL---------AALAAEPENLQAAFAAAQAGADRTLHAsKANAGRA 520
Cdd:PTZ00375  476 vdAVRAALAAGSHSIQELGGARVGDRTMVDVLIPFAealnscpsvNEAASSPELLKACSEEAREAAEATALL-PAKHGRS 554
                         570       580
                  ....*....|....*....|....*..
gi 1730616595 521 SYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:PTZ00375  555 RYLEGKEL-GKKDPGAELVVAWVEALA 580
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
18-326 2.40e-116

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 346.74  E-value: 2.40e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  18 EGTIIASPwNNLARLESDpaiRVVVRRDL-DKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASPSVDAVLTAIQ 96
Cdd:pfam02733   1 EGLAAAHP-DLLRLVPGP---RVVVRADApPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIK 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  97 AVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVAGYFAERGHNLA 173
Cdd:pfam02733  77 AVDGGAGVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVGDSGGTvgrRGVAGTVLVHKIAGAAAEAGASLD 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 174 TVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAEKLSAALPETG- 252
Cdd:pfam02733 157 EVARLAEKVNANTRTMGVALSPCTVPGAGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDDPLLPg 236
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730616595 253 -RLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGPasLVTALDMKGFSLTAIVLEESIEKALLSAVETAG 326
Cdd:pfam02733 237 dEVAVLVNGLGGTPLLELYIVYRRVLEL-LEEKgikvVRSLVGE--YMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
5-201 1.12e-20

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 90.26  E-value: 1.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   5 FFNQRANLVNDVIEGTIIASPWNNLARL--ESDPAIRVVVRRDLDKnnVAVISGGGSGhepahaGFVGKGMLTAAVCGDL 82
Cdd:COG2376    14 FLNDLDAVVGDGDHGINMARGFDAVRAAldAAPADPGVVLRAAGMK--VASVVGGGSG------GLVGTGFLDAAVALKG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  83 FASPSVDAVLTAIQAVT---GDAGcllivKNYTGDRLNFGLAAEKARRMgynVEMLIVGDDislpdnkhprgiagtilvh 159
Cdd:COG2376    86 ETSPTADQVAAALRAADegiQGRG-----VAYTGDKTNFDAAAPAAEAI---EEAVAAGTA------------------- 138
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1730616595 160 kvagyFAErghNLATVLREAQYAAGHTFSLGLALASCHLPQD 201
Cdd:COG2376   139 -----AAA---ALDEAAAAAEKGAEATRSMGAALGRATYPGE 172
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
3-547 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 600.13  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   3 QFFFNQRANLVNDVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 158 VHKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 237 VTLMAEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELAHTPLQ-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 307 AIVLEE---SIEKALLSAVETAGW----QTPVQPREIS---VMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKRevvSSSAPELIEETAVRSYDPQLVAAILESGCAALLELEPHL 395
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554
                         570       580
                  ....*....|....*....|
gi 1730616595 528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
1-547 1.13e-129

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 390.71  E-value: 1.13e-129
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   1 MSQFFFNQRANLVNDVIEGTIIASPwNNLARLESdpaIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCG 80
Cdd:PTZ00375    2 VSKKFINSPEKVVSEAVDGLCMTNN-DSLKRIEN---TNVVVRSDIDKTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCG 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  81 DLFASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDIS--LPDNKHPRGIAGTILV 158
Cdd:PTZ00375   78 SVFASPSTKHVLAAIEYVPNGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAfgTKDIANRRGIAGTVLL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 159 HKVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDaETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVT 238
Cdd:PTZ00375  158 YKILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGN-DPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVK 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 239 LMAEKL-----------SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRIDWL-IGPASLVTALDMKGFSLT 306
Cdd:PTZ00375  237 FLIGILlgkgkkrgggkTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQLAQAGLTVVgVHSGRLMTSLEMHGFSLT 316
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 307 AIVLEESIEKALLSAVETA---------GWQTPVQPRE-ISVMPSSLRSTRVEFEPSENSVVADYVERVTGTLSDLEADL 376
Cdd:PTZ00375  317 LLPIEDEDDLQLLDTNQKPllnfhtpqsSWATAKGPLSaLQLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENYL 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 377 NALDAKVGDGDTGSTFAAGARDIADLLQrRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGA----- 451
Cdd:PTZ00375  397 NELDAEVGDGDLGSGLERSSKAVLESLP-YLPLEANVRKTLTLISKAVADAFGGSSGPLYGAFLLGGANALAEALnggna 475
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 452 --SVAEALNAGLAQMKFYGGADEGDRTMIDALQPAL---------AALAAEPENLQAAFAAAQAGADRTLHAsKANAGRA 520
Cdd:PTZ00375  476 vdAVRAALAAGSHSIQELGGARVGDRTMVDVLIPFAealnscpsvNEAASSPELLKACSEEAREAAEATALL-PAKHGRS 554
                         570       580
                  ....*....|....*....|....*..
gi 1730616595 521 SYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:PTZ00375  555 RYLEGKEL-GKKDPGAELVVAWVEALA 580
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
5-548 2.73e-123

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 373.76  E-value: 2.73e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   5 FFNQRANLVNDVIEGTIIASPwnnlaRLESDPAIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFA 84
Cdd:PRK14479    4 LINDPSTFVEEMLEGFVAAHP-----DLVRLVPGGVVRRTPTPEGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFT 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  85 SPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISL-PDNKHP--RGIAGTILVHKV 161
Cdd:PRK14479   79 SPSADQVYAAIRAADGGAGVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAgrRGIAGTVLVFKI 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 162 AGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPqdAETAPRHH--ADQAELGMGIHGEPGASVIATQNSAEIVTL 239
Cdd:PRK14479  159 AGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLP--GAGEPLFTlpEGEMELGLGIHGEPGIEREALPTADELADR 236
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 240 MAEKLSAALPE--TGRLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGpaSLVTALDMKGFSLTAIVLEES 313
Cdd:PRK14479  237 LVDRILADLPLgaGERVAVLVNGLGATPYEELFVVYGAVARL-LAARgitvVRPEVG--EFVTSLDMAGASLTLMKLDDE 313
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 314 IEKALLSAVETAGWQT--PVQPREISVMPSSlRSTRVEFEPSENS-----VVADYVERVTGTLSDLEADLNALDAKVGDG 386
Cdd:PRK14479  314 LEELWDAPADTPAFRRggAVEPVEYVEAAEE-DDAEEPPRASKASrataaNLVAALDAVAEALIDNEDELGELDAVAGDG 392
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 387 DTGSTFAAGARDIADLLQRRQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQ-----GASVAEALNAGL 461
Cdd:PRK14479  393 DHGIGMARGSKAALAAARAAVEAGAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALGDkdeptAADFAAAVRAAV 472
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 462 AQMKFYGGADEGDRTMIDALQPALAALAAEPENLQAAFAAAQAGADRTLHASKANA------GRASYLNSDSLrGNMDPG 535
Cdd:PRK14479  473 DAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEAAEEGAEATAdlvprmGRARYLGERSL-GTPDAG 551
                         570
                  ....*....|...
gi 1730616595 536 AHAVAMVFKALAQ 548
Cdd:PRK14479  552 AVSLALIFTAIAG 564
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
18-326 2.40e-116

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 346.74  E-value: 2.40e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  18 EGTIIASPwNNLARLESDpaiRVVVRRDL-DKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASPSVDAVLTAIQ 96
Cdd:pfam02733   1 EGLAAAHP-DLLRLVPGP---RVVVRADApPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIK 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  97 AVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVAGYFAERGHNLA 173
Cdd:pfam02733  77 AVDGGAGVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVGDSGGTvgrRGVAGTVLVHKIAGAAAEAGASLD 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 174 TVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAEKLSAALPETG- 252
Cdd:pfam02733 157 EVARLAEKVNANTRTMGVALSPCTVPGAGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDDPLLPg 236
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730616595 253 -RLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGPasLVTALDMKGFSLTAIVLEESIEKALLSAVETAG 326
Cdd:pfam02733 237 dEVAVLVNGLGGTPLLELYIVYRRVLEL-LEEKgikvVRSLVGE--YMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
PRK14481 PRK14481
dihydroxyacetone kinase subunit DhaK; Provisional
5-327 7.55e-98

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 237724  Cd Length: 331  Bit Score: 299.81  E-value: 7.55e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   5 FFNQRANLVNDVIEGTIIASPwnNLARLESDPaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFA 84
Cdd:PRK14481    4 LINDPETVVDEMLEGLVAAHP--DLVTRIDDT--DVIVRKDKPPGKVALVSGGGSGHEPAHAGFVGEGMLDAAVCGAVFT 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  85 SPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKV 161
Cdd:PRK14481   80 SPTPDQILEAIKAVDTGAGVLLIVKNYSGDVMNFEMAAELAEMEGIEVASVVVDDDVAVEDSLYTqgrRGVAGTVFVHKI 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 162 AGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMA 241
Cdd:PRK14481  160 AGAAAEAGASLDEVKALAEKVNPNIRSMGVALSPCTVPAVGKPGFDLGDDEIEIGIGIHGEPGRRREKLKPADEIAEELL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 242 EKLSAALPET--GRLAVMINNLGGVSIAEMAILTRELAHTpLQQR----IDWLIGpaSLVTALDMKGFSLTAIVLEESIE 315
Cdd:PRK14481  240 EKILEDLKLVagDEVLVLVNGMGATPLMELYIVYNDVAEL-LEERgvtvARSLVG--NYMTSLDMAGFSITLLKLDDELL 316
                         330
                  ....*....|..
gi 1730616595 316 KALLSAVETAGW 327
Cdd:PRK14481  317 ELLDAPVDTPAL 328
dhaK1 TIGR02363
dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) ...
5-327 6.49e-86

dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the DhaK subunit of the latter type of dihydroxyacetone kinase, but it specifically excludes the DhaK paralog DhaK2 (TIGR02362) found in the same operon as DhaK and DhaK in the Firmicutes.


Pssm-ID: 274098  Cd Length: 329  Bit Score: 269.23  E-value: 6.49e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   5 FFNQRANLVNDVIEGTIIASPwnNLARLESDPaiRVVVRRDLDKNN-VAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLF 83
Cdd:TIGR02363   4 LINDPEDVVAEMLDGLVKAHP--ELVTLVADT--RVIVRKDKKVNGkVALVSGGGSGHEPAHAGFVGYGMLDAAVPGEVF 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  84 ASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHK 160
Cdd:TIGR02363  80 TSPTPDQILEAIKAVDQGAGVLLIVKNYTGDVMNFEMAAELAEDEGIKVATVVVDDDIAVEDSLYTagrRGVAGTVFVHK 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 161 VAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLM 240
Cdd:TIGR02363 160 IAGAAAEKGASLDELKSLGEKVNPNTKSIGVALTACTVPAVGKPGFDLADDEMEIGVGIHGEPGIRREKMKSSDEIADEL 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 241 AEKL--SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRID---WLIGpaSLVTALDMKGFSLTAIVLEESIE 315
Cdd:TIGR02363 240 LDKLldDLGLQSGDRVIVLVNGMGATPLMELYIFYNDVQRLLEQRGVNvarTLVG--NYMTSLDMAGFSLTLLKLDDELL 317
                         330
                  ....*....|..
gi 1730616595 316 KALLSAVETAGW 327
Cdd:TIGR02363 318 ELWDAPVTTIAL 329
PRK14483 PRK14483
DhaKLM operon coactivator DhaQ; Provisional
4-327 7.20e-68

DhaKLM operon coactivator DhaQ; Provisional


Pssm-ID: 172956  Cd Length: 329  Bit Score: 222.23  E-value: 7.20e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   4 FFFNQRANLVNDVIEGTIIASPwnNLARLesdPAIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLF 83
Cdd:PRK14483    3 KIMNDVQNIVQDMLHGFYFAHP--NLDET---NNIPYVYDIEKDDQLVPIISGGGSGHEPAHIGYVGKGMLTAAVNGSIF 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  84 ASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPD----NKHPRGIAGTILVH 159
Cdd:PRK14483   78 TPPTAEQILAATRLVPKGKGVFFIIKNFEADVAEFSAAIQIARQEGRQIKYIIVHDDISVEDdasfNKRRRGVAGTVLLH 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 160 KVAGYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTL 239
Cdd:PRK14483  158 KILGAAALEGASLDELEQLGLSLTENIATLGVALSPANLPVAGLPSFDLNEDEISYGIGIHGEPGYRKEPFSSSEILAIE 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 240 MAEKLSAAL--PETGRLAVMINNLGGVSIAEMAILT----RELAHTPLQqrIDWlIGPASLVTALDMKGFSLTAIVLEES 313
Cdd:PRK14483  238 LVNKLKSKYrwQKGDNFILLINGLGATTLMEQYIFAndirRLLELEGLQ--ITF-VKVGTLLTSLDMKGISLTLLKVKDP 314
                         330
                  ....*....|....*
gi 1730616595 314 -IEKALLSAVETAGW 327
Cdd:PRK14483  315 dWLDWLKAPTRAAAW 329
PRK11468 PRK11468
dihydroxyacetone kinase subunit DhaK; Provisional
7-327 8.97e-65

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 183150  Cd Length: 356  Bit Score: 214.88  E-value: 8.97e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   7 NQRANLVNDVIEGTIIASPwnNLaRLESDPaiRVVVRRDLD-KNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFAS 85
Cdd:PRK11468    6 NDVEDVLDEQLAGLAKAHP--EL-TLHQDP--VYVTRADAPvAGKVALLSGGGSGHEPMHCGFVGQGMLDGACPGEIFTS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  86 PSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVA 162
Cdd:PRK11468   81 PTPDQMFECAMQVDGGEGVLLIIKNYTGDVLNFETATELLHDSGVKVTTVLIDDDVAVKDSLYTagrRGVANTVLIEKLV 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 163 GYFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAE 242
Cdd:PRK11468  161 GAAAERGYSLDQCAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEMFD 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 243 KL--------------------------SAALPETGRLAVMINNLGGVSIAEMAILTRELAHTPLQQRIDW---LIGPas 293
Cdd:PRK11468  241 TLlengsyhrtlrfwdrqqgswqeeeqtKQPLQSGDRVIALVNNLGATPLSELYGVYNRLATRCEQAGLTIernLIGA-- 318
                         330       340       350
                  ....*....|....*....|....*....|....
gi 1730616595 294 LVTALDMKGFSLTAIVLEESIEKALLSAVETAGW 327
Cdd:PRK11468  319 YCTSLDMQGFSITLLKVDDETLALWDAPVHTPAL 352
dhaK1b TIGR02362
probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase ...
7-327 1.42e-53

probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form with a phosphoprotein donor related to PTS transport proteins. This family represents a protein, unique to the Firmicutes (low GC Gram-positives), that appears to be a divergent second copy of the K subunit of that complex; its gene is always found in operons with the other three proteins of the complex.


Pssm-ID: 213706  Cd Length: 326  Bit Score: 184.62  E-value: 1.42e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   7 NQRANLVNDVIEGTIIASPwnNLARLESDPAIRvvvRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASP 86
Cdd:TIGR02362   4 NEPQNAVSQAIQGIQWAYP--NLVQVPDLPGIY---DSNFDDQQIPIISGGGSGHEPAHWGYVGEGMLSAAIMGDVFVPP 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  87 SVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISL-PDN--KHPRGIAGTILVHKVAG 163
Cdd:TIGR02362  79 TAQDILEAIRQVDRGKGVFVIIKNFEADLSEFSQAIQQARQEGRQIKYIIVHDDISVeHESfkQRRRGVAGTILVHKILG 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 164 YFAERGHNLATVLREAQYAAGHTFSLGLALASCHLPQDAETAPRHHADQAELGMGIHGEPGASVIATQNSAEIVTLMAEK 243
Cdd:TIGR02362 159 AAAAEGASLDELEHIAAALVTNIATIGVAAKSARIPGQSTPSFDLEEGEIYYGIGIHGEPGYRTEPFVSSEHLAVELVNK 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 244 LSAAL--PETGRLAVMINNLGGVSIAE--------MAILTRELAHTPlqqridwLIGPASLVTALDMKGFSLTAIVL-EE 312
Cdd:TIGR02362 239 LKLKFrwQADDHYAVLVNNLGGTTPMEqmvfnndvHELLALEALHLP-------FIKVGTFLTSLDMHGLSLTLLRLkDP 311
                         330
                  ....*....|....*
gi 1730616595 313 SIEKALLSAVETAGW 327
Cdd:TIGR02362 312 QWLDYLNAPVDAAAW 326
Dak2 pfam02734
DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase ...
382-548 1.09e-23

DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.


Pssm-ID: 460668 [Multi-domain]  Cd Length: 175  Bit Score: 98.02  E-value: 1.09e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 382 KVGDGDTGSTFAAGARDIADLLQrrQLPLANLATLLALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQ-----GASVAEA 456
Cdd:pfam02734   1 PVGDGDHGTNMARGFEAALKALE--DLEPASLAEVLKALAMALLSGAGGNSGPLYGQFFRGAAKALKGkeeldAEDLAAA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 457 LNAGLAQMKFYGGADEGDRTMID-------ALQPALAALAAEPENLQAAFAAAQAGADRTLHaSKANAGRASYLNSDSLr 529
Cdd:pfam02734  79 LEAALEAIQARGKARPGDKTMLDvlrpaaeALEAAAEAGEDLAEALEAAVKAAEEGAEATKE-LLAKLGRASYLGERSI- 156
                         170
                  ....*....|....*....
gi 1730616595 530 GNMDPGAHAVAMVFKALAQ 548
Cdd:pfam02734 157 GVVDPGATGLALILEALLE 175
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
5-201 1.12e-20

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 90.26  E-value: 1.12e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595   5 FFNQRANLVNDVIEGTIIASPWNNLARL--ESDPAIRVVVRRDLDKnnVAVISGGGSGhepahaGFVGKGMLTAAVCGDL 82
Cdd:COG2376    14 FLNDLDAVVGDGDHGINMARGFDAVRAAldAAPADPGVVLRAAGMK--VASVVGGGSG------GLVGTGFLDAAVALKG 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595  83 FASPSVDAVLTAIQAVT---GDAGcllivKNYTGDRLNFGLAAEKARRMgynVEMLIVGDDislpdnkhprgiagtilvh 159
Cdd:COG2376    86 ETSPTADQVAAALRAADegiQGRG-----VAYTGDKTNFDAAAPAAEAI---EEAVAAGTA------------------- 138
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 1730616595 160 kvagyFAErghNLATVLREAQYAAGHTFSLGLALASCHLPQD 201
Cdd:COG2376   139 -----AAA---ALDEAAAAAEKGAEATRSMGAALGRATYPGE 172
dha_L_ycgS TIGR02365
dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone ...
373-547 3.58e-14

dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.


Pssm-ID: 274099 [Multi-domain]  Cd Length: 194  Bit Score: 71.23  E-value: 3.58e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 373 EADLNALDAKVGDGDTGSTFAAGARDIADLLQrrqlplanlATLLALIGERLTVV-------MGGSSGVLMSIFFTAAGQ 445
Cdd:TIGR02365  16 KEYLTELDRAIGDGDHGINMARGFSEVKEKLD---------AFKDKTIGEILKNTgmtliskVGGASGPLYGTAFLKASK 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 446 KLEQ-----GASVAEALNAGLAQMKFYGGADEGDRTMIDA---LQPALAALAAEPENLQAAFAAAQAGADRT--LHASKa 515
Cdd:TIGR02365  87 ALKDdeildAEDLAEILQAGLEGIQSRGKATPGEKTMVDVwapVVEALRKAADEPDALAAAREAAEQGAEATkdMQATK- 165
                         170       180       190
                  ....*....|....*....|....*....|..
gi 1730616595 516 naGRASYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02365 166 --GRASYLGERSI-GHIDPGATSSYYLFQALA 194
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
362-548 8.93e-12

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 64.45  E-value: 8.93e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 362 VERVTGTLSDLEADLNALDAKVGDGDTGSTFAAGARDIADLLQrrqLPLANLATLLALIGERLTVVMGGSSGVLMSIFFT 441
Cdd:COG2376     1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRAALD---AAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 442 AAGQKLEQGAS-----VAEALNAGLAQMKFYGGADEGDRTMID-------ALQPALAALAAEPENLQAAFAAAQAGAD-- 507
Cdd:COG2376    78 DAAVALKGETSptadqVAAALRAADEGIQGRGVAYTGDKTNFDaaapaaeAIEEAVAAGTAAAAALDEAAAAAEKGAEat 157
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1730616595 508 RTLHASKanaGRASYLNSDSlRGNMDPGAHAVAMVFKALAQ 548
Cdd:COG2376   158 RSMGAAL---GRATYPGERS-PGHPDPGATSVALLLNGLGA 194
PRK10005 PRK10005
dihydroxyacetone kinase ADP-binding subunit DhaL;
376-548 1.21e-06

dihydroxyacetone kinase ADP-binding subunit DhaL;


Pssm-ID: 182192 [Multi-domain]  Cd Length: 210  Bit Score: 49.35  E-value: 1.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 376 LNALDAKVGDGDTGSTFAAGARDIADLLqrrqlplanLATLLALIGERL-TVVM------GGSSGVLMSIFFTAAGQKLE 448
Cdd:PRK10005   26 LTGLDREIGDADHGLNMNRGFSKVVEKL---------PAIADKDIGFILkNTGMtllssvGGASGPLYGTFFIRAAQATQ 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730616595 449 QGASVA-----EALNAGLAQMKFYGGADEGDRTMIDALQPALAALAAEPEN---LQAAFAAAQAGADRTLHAS---KANA 517
Cdd:PRK10005   97 ARQSLTleelyQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQnlsVPAALNAAVSIAESAAQSTitmQARK 176
                         170       180       190
                  ....*....|....*....|....*....|.
gi 1730616595 518 GRASYLNSDSLrGNMDPGAHAVAMVFKALAQ 548
Cdd:PRK10005  177 GRASYLGERSI-GHQDPGATSVMFMMQALAL 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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