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Conserved domains on  [gi|1730651616|gb|TYG27200|]
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4Fe-4S dicluster domain-containing protein [Klebsiella grimontii]

Protein Classification

formate hydrogenlyase complex iron-sulfur subunit( domain architecture ID 11485882)

formate hydrogenlyase complex iron-sulfur subunit is a 4Fe-4S dicluster domain-containing protein that may function as an electron transfer protein for the hydrogenase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 1-180 2.97e-123

formate hydrogenlyase complex iron-sulfur subunit; Provisional


:

Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 344.71  E-value: 2.97e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616   1 MFTFIKKVIKTGTATHSYPLEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTVETDLAANQLGWQFNLGRCIFCGR 80
Cdd:PRK12387    1 MFKLIKKVIKTGTATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  81 CEEVCPTAAIRLSQEYELAVWKKEDFLQQSRFAICHCRVCERPFAVQKEIDYAIALLKHNGDSRAELHRESFETCPECKR 160
Cdd:PRK12387   81 CEEVCPTAAIKLSQEFELAVWKKEDLLQQSEFALCNCRVCGRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR 160

                         170       180
                  ....*....|....*....|
gi 1730651616 161 QKCLVPSDRIELTRHMREAS 180
Cdd:PRK12387  161 QKCLVPSDRIELTRHMKEAI 180
 
Name Accession Description Interval E-value
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 1-180 2.97e-123

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 344.71  E-value: 2.97e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616   1 MFTFIKKVIKTGTATHSYPLEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTVETDLAANQLGWQFNLGRCIFCGR 80
Cdd:PRK12387    1 MFKLIKKVIKTGTATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  81 CEEVCPTAAIRLSQEYELAVWKKEDFLQQSRFAICHCRVCERPFAVQKEIDYAIALLKHNGDSRAELHRESFETCPECKR 160
Cdd:PRK12387   81 CEEVCPTAAIKLSQEFELAVWKKEDLLQQSEFALCNCRVCGRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR 160

                         170       180
                  ....*....|....*....|
gi 1730651616 161 QKCLVPSDRIELTRHMREAS 180
Cdd:PRK12387  161 QKCLVPSDRIELTRHMKEAI 180
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 33-173 1.11e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 87.84  E-value: 1.11e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  33 PEHNPQQCIGCAACVNACPSNALTVETDLAANqLGWQFNLGRCIFCGRCEEVCPTAAIRLSQEY-ELAVWKKEDFLQQSR 111
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNGAIA-RGPEIDEDKCVFCGACVEVCPTGAIELTPEGkEYVPKEKEAEIDEEK 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1730651616 112 faICHCRVCERPFAVQkeidyAIALlkhngdSRAELHRESFETCPECKR--QKClvPSDRIELT 173
Cdd:cd10549    80 --CIGCGLCVKVCPVD-----AITL------EDELEIVIDKEKCIGCGIcaEVC--PVNAIKLV 128
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-106 7.41e-21

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 82.85  E-value: 7.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  15 THSYPLEPMPVDKNFRG-----KPEHNPQQCIGCAACVNACPSNALTVET----DLAANQLGWQFNLGRCIFCGRCEEVC 85
Cdd:TIGR01971  15 TVQYPEEKLYLPPRFRGrivltRDPNGEEKCIGCTLCAAVCPADAIRVVPaegeDGKRRLKFYEINFGRCIFCGLCEEAC 94

                          90       100
                  ....*....|....*....|.
gi 1730651616  86 PTAAIRLSQEYELAVWKKEDF 106
Cdd:TIGR01971  95 PTDAIVLTPEFELATYTRSDL 115
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 37-105 2.70e-17

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 72.09  E-value: 2.70e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  37 PQQCIGCAACVNACPSNALTVETDLAANQlgWQFNLGRCIFCGRCEEVCPTAAIRLSQeYELAVWKKED 105
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEPGKV--YVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 40-89 2.98e-10

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 53.30  E-value: 2.98e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  40 CIGCAACVNACPSNALTV-ETDLAANQLGWQFNLGRCIFCGRCEEVCPTAA 89
Cdd:pfam12838   1 CIGCGACVAACPVGAITLdEVGEKKGTKTVVIDPERCVGCGACVAVCPTGA 51
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 40-90 9.32e-05

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 41.38  E-value: 9.32e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  40 CIGCAACVNACPSNALTVETDLAAnqlgWQfnlGRCIFCGRCEEVCPTAAI 90
Cdd:NF038196  187 CIGCGICAKVCPVNNIEMEDGKPV----WG---HNCTHCLACIHRCPKEAI 230
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 74-104 5.20e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 36.38  E-value: 5.20e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1730651616  74 RCIFCGRCEEVCPTAAIRLSQEYelAVWKKE 104
Cdd:NF038196  186 KCIGCGICAKVCPVNNIEMEDGK--PVWGHN 214
 
Name Accession Description Interval E-value
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 1-180 2.97e-123

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 344.71  E-value: 2.97e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616   1 MFTFIKKVIKTGTATHSYPLEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTVETDLAANQLGWQFNLGRCIFCGR 80
Cdd:PRK12387    1 MFKLIKKVIKTGTATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  81 CEEVCPTAAIRLSQEYELAVWKKEDFLQQSRFAICHCRVCERPFAVQKEIDYAIALLKHNGDSRAELHRESFETCPECKR 160
Cdd:PRK12387   81 CEEVCPTAAIKLSQEFELAVWKKEDLLQQSEFALCNCRVCGRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR 160

                         170       180
                  ....*....|....*....|
gi 1730651616 161 QKCLVPSDRIELTRHMREAS 180
Cdd:PRK12387  161 QKCLVPSDRIELTRHMKEAI 180
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 1-180 6.24e-69

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 207.30  E-value: 6.24e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616   1 MFTFIKKVIKTGTATHSYPLEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTVETDLAANQLGWQFNLGRCIFCGR 80
Cdd:PRK08222    1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACTCACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  81 CEEVCPTAAIRLSQEYELAVWKKEDFLQQSRFAICHCRVCERPFAVQKEIDYAIALLKH--NGDSRAELHRESFETCPEC 158
Cdd:PRK08222   81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQqqNAPQNREMLRAQASVCPEC 160

                         170       180
                  ....*....|....*....|..
gi 1730651616 159 KRQKCLVpSDRIELTRHMREAS 180
Cdd:PRK08222  161 KQRATLI-NDDTDVPLVAKEQL 181
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
3-107 1.83e-23

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 90.71  E-value: 1.83e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616   3 TFIKKVIktgtaTHSYPLEPMPVDKNFRG-----KPEHNPQQCIGCAACVNACPSNALTVETDLAANQ----LGWQFNLG 73
Cdd:PRK05888   23 YFFKKKV-----TIQYPEEKLPLSPRFRGrhalrRDPNGEERCIACKLCAAICPADAITIEAAEREDGrrrtTRYDINFG 97

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1730651616  74 RCIFCGRCEEVCPTAAIRLSQEYELAVWKKEDFL 107
Cdd:PRK05888   98 RCIFCGFCEEACPTDAIVETPDFELATETREELI 131
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 33-173 1.11e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 87.84  E-value: 1.11e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  33 PEHNPQQCIGCAACVNACPSNALTVETDLAANqLGWQFNLGRCIFCGRCEEVCPTAAIRLSQEY-ELAVWKKEDFLQQSR 111
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNGAIA-RGPEIDEDKCVFCGACVEVCPTGAIELTPEGkEYVPKEKEAEIDEEK 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1730651616 112 faICHCRVCERPFAVQkeidyAIALlkhngdSRAELHRESFETCPECKR--QKClvPSDRIELT 173
Cdd:cd10549    80 --CIGCGLCVKVCPVD-----AITL------EDELEIVIDKEKCIGCGIcaEVC--PVNAIKLV 128
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-106 7.41e-21

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 82.85  E-value: 7.41e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  15 THSYPLEPMPVDKNFRG-----KPEHNPQQCIGCAACVNACPSNALTVET----DLAANQLGWQFNLGRCIFCGRCEEVC 85
Cdd:TIGR01971  15 TVQYPEEKLYLPPRFRGrivltRDPNGEEKCIGCTLCAAVCPADAIRVVPaegeDGKRRLKFYEINFGRCIFCGLCEEAC 94

                          90       100
                  ....*....|....*....|.
gi 1730651616  86 PTAAIRLSQEYELAVWKKEDF 106
Cdd:TIGR01971  95 PTDAIVLTPEFELATYTRSDL 115
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 1-105 1.54e-18

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 76.80  E-value: 1.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616   1 MFTFIKKVIKTGT---ATHSYP-LEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTVETDLAANQLgWqfnLGRCI 76
Cdd:PRK08348    1 RLPLLPTVLRNLFkkpATNLFPaTEPVPVPEDFRGKILYDVDKCVGCRMCVTVCPAGVFVYLPEIRKVAL-W---TGRCV 76

                          90       100
                  ....*....|....*....|....*....
gi 1730651616  77 FCGRCEEVCPTAAIRLSQEYELAVWKKED 105
Cdd:PRK08348   77 FCGQCVDVCPTGALQMSDDFLLASYDRFD 105
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 37-105 2.70e-17

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 72.09  E-value: 2.70e-17
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  37 PQQCIGCAACVNACPSNALTVETDLAANQlgWQFNLGRCIFCGRCEEVCPTAAIRLSQeYELAVWKKED 105
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEPGKV--YVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66
ndhI TIGR00403
NADH-plastoquinone oxidoreductase subunit I protein; [Energy metabolism, Electron transport]
 15-106 1.40e-15

NADH-plastoquinone oxidoreductase subunit I protein; [Energy metabolism, Electron transport]


Pssm-ID: 129498 [Multi-domain]  Cd Length: 183  Bit Score: 70.71  E-value: 1.40e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  15 THSYPLEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTV----ETDLAANQL-GWQFNLGRCIFCGRCEEVCPTAA 89
Cdd:TIGR00403  39 TIQYPYEKLIPSERFRGRIHFEFDKCIACEVCVRVCPINLPVVdwefNKAIKKKQLkNYSIDFGVCIFCGNCVEYCPTNC 118

                          90
                  ....*....|....*..
gi 1730651616  90 IRLSQEYELAVWKKEDF 106
Cdd:TIGR00403 119 LSMTEEYELSTYDRHEL 135
ndhI CHL00014
NADH dehydrogenase subunit I
 15-101 2.15e-15

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 69.79  E-value: 2.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  15 THSYPLEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTV----ETDLAANQL-GWQFNLGRCIFCGRCEEVCPTAA 89
Cdd:CHL00014   36 TIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVdwklETDIRKKRLlNYSIDFGVCIFCGNCVEYCPTNC 115

                          90
                  ....*....|..
gi 1730651616  90 IRLSQEYELAVW 101
Cdd:CHL00014  116 LSMTEEYELSTY 127
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
31-103 6.68e-13

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 60.90  E-value: 6.68e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  31 GKPEHNPQQCIGCAACVNACPSNALTVETDlaanqlGWQFNLGRCIFCGRCEEVCPTAAIRLSQEYELAVWKK 103
Cdd:COG2768     4 GKPYVDEEKCIGCGACVKVCPVGAISIEDG------KAVIDPEKCIGCGACIEVCPVGAIKIEWEEDEEFQEK 70
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 32-94 4.07e-12

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 58.52  E-value: 4.07e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTVETDLAAnqlgwqFNLGRCIFCGRCEEVCPTAAIRLSQ 94
Cdd:COG2221     9 PPKIDEEKCIGCGLCVAVCPTGAISLDDGKLV------IDEEKCIGCGACIRVCPTGAIKGEK 65
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 30-92 1.70e-10

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 54.35  E-value: 1.70e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  30 RGKPEHNPQQCIGCAACVNACPSNALTVETDLAanqlgWQFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:COG1149     3 RKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGA-----PVVDPDLCTGCGACVGVCPTGAITL 60
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 40-89 2.98e-10

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 53.30  E-value: 2.98e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  40 CIGCAACVNACPSNALTV-ETDLAANQLGWQFNLGRCIFCGRCEEVCPTAA 89
Cdd:pfam12838   1 CIGCGACVAACPVGAITLdEVGEKKGTKTVVIDPERCVGCGACVAVCPTGA 51
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 32-97 7.00e-10

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 53.13  E-value: 7.00e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTVETDLAAnqlgwQFNLGRCIFCGRCEEVCPTAAIRLSQEYE 97
Cdd:COG1144    24 RPVVDEDKCIGCGLCWIVCPDGAIRVDDGKYY-----GIDYDYCKGCGICAEVCPVKAIEMVPEEK 84
NapF COG1145
Ferredoxin [Energy production and conversion];
32-92 1.14e-09

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 55.88  E-value: 1.14e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTvetdLAANQLGWQFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:COG1145   176 KAVIDAEKCIGCGLCVKVCPTGAIR----LKDGKPQIVVDPDKCIGCGACVKVCPVGAISL 232
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
30-100 1.45e-09

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 53.51  E-value: 1.45e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  30 RGKPEHNPQQCIGC--AACVNACPSNALTVETDlaanqlGWQFNLGRCIFCGRCEEVCPTAAIRLSQEYELAV 100
Cdd:COG1142    42 RKAGVSAPVQCRHCedAPCAEVCPVGAITRDDG------AVVVDEEKCIGCGLCVLACPFGAITMVGEKSRAV 108
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 36-100 3.35e-09

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 50.86  E-value: 3.35e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  36 NPQQCIGCAACVNACPSNALTVETD----LAANQlgwqfnlGRCIFCGRCEEVCPTAAIRLSQEYELAV 100
Cdd:COG1146     6 DTDKCIGCGACVEVCPVDVLELDEEgkkaLVINP-------EECIGCGACELVCPVGAITVEDDEPEEQ 67
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
33-92 8.10e-09

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 53.71  E-value: 8.10e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  33 PEHNPQQCIGCAACVNACPSNALTVETDLAAnqlgwQFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:COG1148   491 AEVDPEKCTGCGRCVEVCPYGAISIDEKGVA-----EVNPALCKGCGTCAAACPSGAISL 545
PRK13984 PRK13984
putative oxidoreductase; Provisional
 19-107 1.23e-08

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 53.23  E-value: 1.23e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  19 PLEPMPVDKNFRGKPEHNPQQCIGCAACVNACPSNALT-VETDLAANQLGWQ-----FNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:PRK13984   26 PNVKREAAERYRGFHINDWEKCIGCGTCSKICPTDAITmVEVPDLPQEYGKKpqrpvIDYGRCSFCALCVDICTTGSLKM 105

                          90
                  ....*....|....*
gi 1730651616  93 SQEYELAVWKKEDFL 107
Cdd:PRK13984  106 TREYIHISPDPEDFI 120
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
 33-104 1.55e-08

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 52.83  E-value: 1.55e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  33 PEHNPQQCIGCAACVNACPSNaltvetdLAANQLGW-----------QFNLGRCIFCGRCEEVCPtAAIRLSQEYELAvw 101
Cdd:COG4656   359 PPPEEQPCIRCGRCVDACPMG-------LLPQQLYWyaragdfdkaeEYNLMDCIECGCCSYVCP-SKIPLVQYIRLA-- 428


                  ...
gi 1730651616 102 KKE 104
Cdd:COG4656   429 KAE 431
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 36-92 1.83e-08

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 49.27  E-value: 1.83e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  36 NPQQCIGCAACVNACPSNALTVETDLAAnqlgwqFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:COG4231    20 DEDKCTGCGACVKVCPADAIEEGDGKAV------IDPDLCIGCGSCVQVCPVDAIKL 70
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
40-92 3.20e-08

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 51.86  E-value: 3.20e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  40 CIGCAACVNACPSNALTVETDLAanqlgwQFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:PRK07118  215 CIGCGKCVKACPAGAITMENNLA------VIDQEKCTSCGKCVEKCPTKAIRI 261
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
32-93 3.24e-08

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 51.60  E-value: 3.24e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1730651616  32 KPEHNPQQCIGCAACVNACPsnaltVETDLAANQLgwqfNLGRCIFCGRCEEVCPTAAIRLS 93
Cdd:COG0348   204 RVRYDRGDCIDCGLCVKVCP-----MGIDIRKGEI----NQSECINCGRCIDACPKDAIRFS 256
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 32-86 4.41e-08

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 47.63  E-value: 4.41e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTVETDLAANQLGWQ-FNLGRCIFCGRCEEVCP 86
Cdd:pfam13237   1 KVVIDPDKCIGCGRCTAACPAGLTRVGAIVERLEGEAVrIGVWKCIGCGACVEACP 56
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 23-92 7.59e-08

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 48.93  E-value: 7.59e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  23 MPVDKNFRGKPEHNPQQCIGCAACVNACPSNALTVETDLAANQLGWQ---FNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:cd10549    25 LGPNGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKeaeIDEEKCIGCGLCVKVCPVDAITL 97
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
36-90 8.30e-08

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 50.79  E-value: 8.30e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1730651616  36 NPQQCIGCAACVNACPSNALTVETDLAanqlgwQFNLGRCIFCGRCEEVCPTAAI 90
Cdd:COG4624    89 DKEKCKNCYPCVRACPVKAIKVDDGKA------EIDEEKCISCGQCVAVCPFGAI 137
rnfC TIGR01945
electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in ...
 33-99 1.04e-07

electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the C subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273888 [Multi-domain]  Cd Length: 435  Bit Score: 50.42  E-value: 1.04e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1730651616  33 PEHNPQQCIGCAACVNACPSNaltvetdLAANQLGW-----------QFNLGRCIFCGRCEEVCPtAAIRLSQEYELA 99
Cdd:TIGR01945 358 PESPEKPCIRCGKCVQVCPMN-------LLPQQLNWlaladefdeaeEHNLMDCIECGCCSYVCP-SNIPLVQYIRQA 427
PRK13795 PRK13795
hypothetical protein; Provisional
 40-88 1.65e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 49.99  E-value: 1.65e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1730651616  40 CIGCAACVNACPSNALTVEtdlaaNQLGWQF-NLGRCIFCGRCEEVCPTA 88
Cdd:PRK13795  583 CVGCGVCVGACPTGAIRIE-----EGKRKISvDEEKCIHCGKCTEVCPVV 627
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 40-135 3.61e-07

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 48.45  E-value: 3.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  40 CIGCAACVNACPSNALTVetdlAANQLGwQFNLGRCIFCGRCEEVCPTAAIRL---SQEYELAVWKKEDFLQQSRFAICH 116
Cdd:COG2878   139 CIGCGDCIKACPFDAIVG----AAKGMH-TVDEDKCTGCGLCVEACPVDCIEMvpvSPTVVVSSWDKGKAVRKVVGCIGL 213

                          90
                  ....*....|....*....
gi 1730651616 117 CRVCERPFAVQKEIDYAIA 135
Cdd:COG2878   214 CCKKCCPAAAITVNNLAAI 232
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 40-91 4.79e-07

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 47.25  E-value: 4.79e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  40 CIGCAACVNACPSNALTVETDLAANQLGWQ----FNLGRCIFCG-RCEEVCPTAAIR 91
Cdd:cd16373    16 CIRCGLCVEACPTGVIQPAGLEDGLEGGRTpyldPREGPCDLCCdACVEVCPTGALR 72
PRK09898 PRK09898
ferredoxin-like protein;
38-92 6.19e-07

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 47.52  E-value: 6.19e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1730651616  38 QQCIGCAACVNACPSNALTVETDLAANqlgwqfnlGRCIFCGRCEEVCPTAAIRL 92
Cdd:PRK09898  154 KRCIGCSACTTACPWMMATVNTESKKS--------SKCVLCGECANACPTGALKI 200
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 33-113 6.30e-07

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 48.41  E-value: 6.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  33 PEHNPQQ-CIGCAACVNACPSnaltvetDLAANQLGW-----------QFNLGRCIFCGRCEEVCPtAAIRLSQEYELA- 99
Cdd:PRK05035  364 PPPPPEQpCIRCGACADACPA-------SLLPQQLYWfakaeehdkaqEYNLFDCIECGACAYVCP-SNIPLVQYYRQAk 435

                          90
                  ....*....|....*.
gi 1730651616 100 --VWKKEDFLQQSRFA 113
Cdd:PRK05035  436 aeIRAIEQEKKKAEEA 451
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 39-95 6.79e-07

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 48.33  E-value: 6.79e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  39 QCIGCAACVNACPSNALTVetdlAANQLGWQFNLGRCIFCGRCEEVCPTAAIRLSQE 95
Cdd:PRK12771  511 NCFECDNCYGACPQDAIIK----LGPGRRYHFDYDKCTGCHICADVCPCGAIEMGPG 563
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 29-90 7.42e-07

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 45.71  E-value: 7.42e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1730651616  29 FRGKPEHNPQQCIGCAACVNACPSNALTVEtdlAANQLGWQFNLGRCIFCGRCEEVCPTAAI 90
Cdd:TIGR00402  25 WSARESLFSAVCTRCGECASACENNILQLG---QQGQPTVEFDNAECDFCGKCAEACPTNAF 83
Fer4_9 pfam13187
4Fe-4S dicluster domain;
39-90 1.16e-06

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 43.70  E-value: 1.16e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1730651616  39 QCIGCAACVNACPSNALT---VETDLAANQLGWqfnlgRCIFCGRCEEVCPTAAI 90
Cdd:pfam13187   1 KCTGCGACVAACPAGAIVpdlVGQTIRGDIAGL-----ACIGCGACVDACPRGAI 50
SdhB/FrdB COG0479
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and ...
 39-90 1.49e-06

Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440247 [Multi-domain]  Cd Length: 230  Bit Score: 46.66  E-value: 1.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  39 QCIGCAACVNACPSnaltVETDL-----AANQLGWQFN--------------------LGRCIFCGRCEEVCP-----TA 88
Cdd:COG0479   143 ECILCGACVAACPN----VWANPdflgpAALAQAYRFAldprdeeteerlealedeegVWRCTTCGNCTEVCPkgippTK 218


                  ..
gi 1730651616  89 AI 90
Cdd:COG0479   219 AI 220
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 38-95 2.52e-06

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 44.93  E-value: 2.52e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  38 QQCIGCAACVNACPSNALTVETDlaanqlGW---QFNLGRCIFCGRCEEVCPTAAIRLSQE 95
Cdd:cd10564    13 DLCTRCGDCVEACPEGIIVRGDG------GFpelDFSRGECTFCGACAEACPEGALDPARE 67
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 37-100 4.18e-06

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 44.30  E-value: 4.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1730651616  37 PQQCIGC--AACVNACPSNALTVETDLAAnqlgwQFNLGRCIFCGRCEEVCPTAAIRLSQEYELAV 100
Cdd:cd04410    47 PVSCMHCedPPCVKACPTGAIYKDEDGIV-----LIDEDKCIGCGSCVEACPYGAIVFDPEPGKAV 107
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 36-111 4.61e-06

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 45.89  E-value: 4.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  36 NPQQCIGCAACVNACPSNALTVE-TDLAANQLGWQFNlgRCIFC-GR-----CEEVCPTAAIRLSQEYELAVWKKEDFLQ 108
Cdd:PRK12769   83 NQQKCIGCKSCVVACPFGTMQIVlTPVAAGKVKATAH--KCDLCaGRengpaCVENCPADALQLVTEQALSGMAKSRRLR 160


                  ...
gi 1730651616 109 QSR 111
Cdd:PRK12769  161 TAR 163
Rama_corrin_act TIGR04270
methylamine methyltransferase corrinoid protein reductive activase; Members of this family ...
 40-94 6.37e-06

methylamine methyltransferase corrinoid protein reductive activase; Members of this family occur as paralogs in species capable of generating methane from mono-, di-, and tri-methylamine. Members include RamA (Reductive Activation of Methyltransfer, Amines) from Methanosarcina barkeri MS (DSM 800). Member proteins have two C-terminal motifs with four Cys each, likely to bind one 4Fe-4S cluster per motif.


Pssm-ID: 211993 [Multi-domain]  Cd Length: 535  Bit Score: 45.52  E-value: 6.37e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1730651616  40 CIGCAACVNACPSNALTV-ETDlaanqlGWQFNLGRCI--FCGRCEEVCPTAAIRLSQ 94
Cdd:TIGR04270 481 CIACQKCVKECPGKALSIlESE------PPRIDTDRCLgtACRRCERVCPEKVFDIRN 532
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
31-92 7.93e-06

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 43.49  E-value: 7.93e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1730651616  31 GKPEHNPQQCIGCAACVNACPSNALTVETDLAANQlgwqfnLGRCIFCG------RCEEVCPTAAIRL 92
Cdd:COG1142    74 GAVVVDEEKCIGCGLCVLACPFGAITMVGEKSRAV------AVKCDLCGgreggpACVEACPTGALRL 135
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 36-92 1.37e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 42.71  E-value: 1.37e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  36 NPQQCIGCAACVNACPSNALTVETDlaanqlgwQFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:cd16372    75 NKKLCVGCLMCVGFCPEGAMFKHED--------YPEPFKCIACGICVKACPTGALEL 123
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 39-87 1.48e-05

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 44.32  E-value: 1.48e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1730651616  39 QCIGCAACVNACPsNALTVETDLAANQLGwqfNLG-------RCIFCGRCEEVCPT 87
Cdd:cd01916   366 KCTDCGWCTRACP-NSLRIKEAMEAAKEG---DFSgladlfdQCVGCGRCEQECPK 417
psaC CHL00065
photosystem I subunit VII
 40-87 1.83e-05

photosystem I subunit VII


Pssm-ID: 177005 [Multi-domain]  Cd Length: 81  Bit Score: 41.29  E-value: 1.83e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1730651616  40 CIGCAACVNACPSNAL-TVETD-LAANQLGWQFNLGRCIFCGRCEEVCPT 87
Cdd:CHL00065   11 CIGCTQCVRACPTDVLeMIPWDgCKAKQIASAPRTEDCVGCKRCESACPT 60
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 36-92 3.19e-05

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 43.48  E-value: 3.19e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  36 NPQQCIGC--AACVNACPSNALTVETDLAanqlgwQFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:PRK12809   52 NPVACHHCnnAPCVTACPVNALTFQSDSV------QLDEQKCIGCKRCAIACPFGVVEM 104
PRK06273 PRK06273
ferredoxin; Provisional
 40-86 4.53e-05

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 41.62  E-value: 4.53e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1730651616  40 CIGCAACVNACPSNALTVEtDLAANQL--GW------QFNLGRCIFCGRCEEVCP 86
Cdd:PRK06273   51 CIGCGGCANVCPTKAIEMI-PVEPVKIteGYvktkipKIDYEKCVYCLYCHDFCP 104
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 32-95 5.46e-05

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 42.29  E-value: 5.46e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTVETDLAANQLGWQFNL-------GRCIFCGRCEEVCPTAAIRLSQE 95
Cdd:PRK14028  241 KPVIDHSKCIMCRKCWLYCPDDAIIEAWREAEGPRGRKFRMkmidfdyQYCKGCGVCAEVCPTGAIQMVRE 311
porD PRK09625
pyruvate flavodoxin oxidoreductase subunit delta; Reviewed
 32-105 6.49e-05

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 236596 [Multi-domain]  Cd Length: 133  Bit Score: 40.89  E-value: 6.49e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTVETDlaaNQLGWQFNLgrCIFCGRCEEVCPTAAIRL-------SQEYELAVW-KK 103
Cdd:PRK09625   53 KPVHNNEICINCFNCWVYCPDAAILSRDK---KLKGVDYSH--CKGCGVCVEVCPTNPKSLlmfeeqiENETALTQWpKK 127


                  ..
gi 1730651616 104 ED 105
Cdd:PRK09625  128 EE 129
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 38-104 7.13e-05

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 42.32  E-value: 7.13e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1730651616  38 QQCIGCAACVNACPSNALTVETDLAAnqlgwqfnlgRCIFCGR-------CEEVCPTAAIRLSQEYELAVWKKE 104
Cdd:PRK12809   85 QKCIGCKRCAIACPFGVVEMVDTIAQ----------KCDLCNQrssgtqaCIEVCPTQALRLMDDKGLQQIKVA 148
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 40-90 9.32e-05

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 41.38  E-value: 9.32e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  40 CIGCAACVNACPSNALTVETDLAAnqlgWQfnlGRCIFCGRCEEVCPTAAI 90
Cdd:NF038196  187 CIGCGICAKVCPVNNIEMEDGKPV----WG---HNCTHCLACIHRCPKEAI 230
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 33-95 1.24e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 39.87  E-value: 1.24e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1730651616  33 PEHNPQQCIGC--AACVNACPSNALTVETDLAAnqlgWQFNLGRCIFCGRCEEVCPTAAIRLSQE 95
Cdd:cd10550    42 GLDVPVVCRQCedAPCVEACPVGAISRDEETGA----VVVDEDKCIGCGMCVEACPFGAIRVDPE 102
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 31-64 1.77e-04

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 38.17  E-value: 1.77e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1730651616  31 GKPEHNPQQCIGCAACVNACPSNALTVETDLAAN 64
Cdd:COG1149    34 GAPVVDPDLCTGCGACVGVCPTGAITLEEREAGK 67
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 40-92 1.90e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 39.48  E-value: 1.90e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1730651616  40 CIGCAACVNACPSNALTV--ETDLAAnqlgwqfnlgRCIFCG---RCEEVCPTAAIRL 92
Cdd:cd10550    82 CIGCGMCVEACPFGAIRVdpETGKAI----------KCDLCGgdpACVKVCPTGALEF 129
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 31-63 2.03e-04

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 38.10  E-value: 2.03e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1730651616  31 GKPEHNPQQCIGCAACVNACPSNALTVETDLAA 63
Cdd:COG4231    44 GKAVIDPDLCIGCGSCVQVCPVDAIKLEKRVPE 76
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
31-92 2.12e-04

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 40.69  E-value: 2.12e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  31 GKPEHNPQQCIGCAACVNACPSNALTVETDLA-----------------ANQLGwqfnlgrCIFCGRCEEVCPTAAIRL 92
Cdd:PRK07118  161 GLPVVDEDKCTGCGACVKACPRNVIELIPKSArvfvacnskdkgkavkkVCEVG-------CIGCGKCVKACPAGAITM 232
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 34-92 2.13e-04

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 39.29  E-value: 2.13e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1730651616  34 EHNPQQCIGCAACVNACPSNALTVETDLAANQlgwqfnlgRCIFCG---------RCEEVCPTAAIRL 92
Cdd:cd04410    76 LIDEDKCIGCGSCVEACPYGAIVFDPEPGKAV--------KCDLCGdrldeglepACVKACPTGALTF 135
PLN00071 PLN00071
photosystem I subunit VII; Provisional
 40-87 2.40e-04

photosystem I subunit VII; Provisional


Pssm-ID: 177700 [Multi-domain]  Cd Length: 81  Bit Score: 38.39  E-value: 2.40e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1730651616  40 CIGCAACVNACPSNAL-TVETD-LAANQLGWQFNLGRCIFCGRCEEVCPT 87
Cdd:PLN00071   11 CIGCTQCVRACPTDVLeMIPWDgCKAKQIASAPRTEDCVGCKRCESACPT 60
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 37-100 2.63e-04

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 39.55  E-value: 2.63e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1730651616  37 PQQCIGC--AACVNACPSNALTVETDLAanqlgwQFNLGRCIFCGRCEEVCPTAAIRLSQEYELAV 100
Cdd:cd10554    53 PVQCRQCedAPCANVCPVGAISQEDGVV------QVDEERCIGCKLCVLACPFGAIEMAPTTVPGV 112
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 37-100 2.86e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 39.18  E-value: 2.86e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1730651616  37 PQQCIGC--AACVNACPSNALTVETDLAAnqlgwQFNLGRCIFCGRCEEVCPTAAIRLSQEYELAV 100
Cdd:cd16374    40 PVRCRHCedAPCMEVCPTGAIYRDEDGAV-----LVDPDKCIGCGMCAMACPFGVPRFDPSLKVAV 100
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
40-92 3.02e-04

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 39.92  E-value: 3.02e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  40 CIGCAACVNACPSNALTVETDLAanqlgwQFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:PRK07118  141 CLGLGSCVAACPFDAIHIENGLP------VVDEDKCTGCGACVKACPRNVIEL 187
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 43-98 3.14e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 39.16  E-value: 3.14e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1730651616  43 CAACVNACPSNALTVETDLAAN-QLGW-QFNLGRCI------FCGRCEEVCPTAAIRLSQEYEL 98
Cdd:cd16373    59 CDACVEVCPTGALRPLDLEEQKvKMGVaVIDKDRCLawqggtDCGVCVEACPTEAIAIVLEDDV 122
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 35-90 3.29e-04

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 39.54  E-value: 3.29e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  35 HNPQQCIGCAACVNACPSNALtvetdlaanqlgwQFNLGR-----CIFCG---------RCEEVCPTAAI 90
Cdd:COG0437    87 VDYDKCIGCRYCVAACPYGAP-------------RFNPETgvvekCTFCAdrldegllpACVEACPTGAL 143
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 40-122 3.44e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 38.79  E-value: 3.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  40 CIGC--AACVNACPSNALTVetdlaANQLGWQFNLGRCIFCGRCEEVCPTAAIRLSQEYELAVwkkedflqqsrfaIC-H 116
Cdd:cd16370    53 CRACedPPCAEACPTGALEP-----RKGGGVVLDKEKCIGCGNCVKACIVGAIFWDEETNKPI-------------ICiH 114


                  ....*.
gi 1730651616 117 CRVCER 122
Cdd:cd16370   115 CGYCAR 120
Fer4_16 pfam13484
4Fe-4S double cluster binding domain;
40-86 3.59e-04

4Fe-4S double cluster binding domain;


Pssm-ID: 463893 [Multi-domain]  Cd Length: 65  Bit Score: 37.47  E-value: 3.59e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1730651616  40 CIGCAACVNACPSNAL----------------TVETDLAANQLGWQFNLGRCIFCGRCEEVCP 86
Cdd:pfam13484   1 CGSCGKCIDACPTGAIvgpegvldarrcisylTIEKKGLIPDELRCLLGNRCYGCDICQDVCP 63
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 35-90 4.41e-04

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 39.05  E-value: 4.41e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  35 HNPQQCIGCAACVNACPSNALTV-ETDLAANQLGWQFNLGR---CIFC------GR---CEEVCPTAAI 90
Cdd:cd10551    80 VDYDKCIGCRYCMAACPYGARYFnPEEPHEFGEVPVRPKGVvekCTFCyhrldeGLlpaCVEACPTGAR 148
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 32-95 4.98e-04

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 38.09  E-value: 4.98e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTVETDlaanqlGWQ-FNLGRCIFCGRCEEVCPTAAIRLSQE 95
Cdd:PRK09624   45 MPEFNRDKCVRCYLCYIYCPEPAIYLDEE------GYPvFDYDYCKGCGICANECPTKAIEMVRE 103
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 40-93 5.25e-04

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 39.48  E-value: 5.25e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1730651616  40 CIGCAACVNACPSNALTVETDLAANQlgwqfNLGRCIFCGRCEEVCPTAAIRLS 93
Cdd:PRK00783  171 CDECEKCVEACPRGVLELKEGKLVVT-----DLLNCSLCKLCERACPGKAIRVS 219
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 38-92 5.97e-04

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 38.44  E-value: 5.97e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  38 QQCIGC--AACVNACPSNALTVETDLAANqlgwqFNLGRCIFCGRCEEVCPTAAIRL 92
Cdd:cd10562    68 RQCMHCtdAACVKVCPTGALYKTENGAVV-----VDEDKCIGCGYCVAACPFDVPRY 119
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 38-91 6.66e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 38.39  E-value: 6.66e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  38 QQCIGCAACVNACPSNALTVETDLAANQLgwQFNLGRCIFCGRCEEVCPT---AAIR 91
Cdd:cd16373    97 QGGTDCGVCVEACPTEAIAIVLEDDVLRP--VVDEDKCVGCGLCEYVCPVeppKAIV 151
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 36-92 6.66e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 38.02  E-value: 6.66e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  36 NPQQCIGCAACVNACPSNALTVETDLAANQLgwqfnlgrCIFCGRCEEVCPTAAIRL 92
Cdd:cd16370    81 DKEKCIGCGNCVKACIVGAIFWDEETNKPII--------CIHCGYCARYCPHDVLAM 129
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
30-58 1.13e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 38.69  E-value: 1.13e-03
                          10        20
                  ....*....|....*....|....*....
gi 1730651616  30 RGKPEHNPQQCIGCAACVNACPSNALTVE 58
Cdd:COG1148   518 KGVAEVNPALCKGCGTCAAACPSGAISLK 546
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 37-92 1.20e-03

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 37.85  E-value: 1.20e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1730651616  37 PQQCIGCAACVNACPSNAL--------TVETDLaanqlgwqfnlgrCIFCGRCEEVCPTAAIRL 92
Cdd:TIGR01944 112 EDNCIGCTKCIQACPVDAIvgaakamhTVIADE-------------CTGCDLCVEPCPTDCIEM 162
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 69-91 1.37e-03

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 34.92  E-value: 1.37e-03
                          10        20
                  ....*....|....*....|...
gi 1730651616  69 QFNLGRCIFCGRCEEVCPTAAIR 91
Cdd:pfam00037   2 VIDEEKCIGCGACVEVCPVGAIT 24
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 36-98 1.51e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 37.25  E-value: 1.51e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1730651616  36 NPQQCIGCAACVNACPSNALTVETDLAANQlgwqfnlgRCIFCGR---------CEEVCPTAAIRLSQEYEL 98
Cdd:cd16374    71 DPDKCIGCGMCAMACPFGVPRFDPSLKVAV--------KCDLCIDrrregklpaCVEACPTGALKFGDIEEL 134
PRK12576 PRK12576
succinate dehydrogenase/fumarate reductase iron-sulfur subunit;
26-86 1.54e-03

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;


Pssm-ID: 237143 [Multi-domain]  Cd Length: 279  Bit Score: 38.19  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  26 DKNFRGKPEHNPQ-----QCIGCAACVNACPSNALTVE-TDLAANQLGWQF------------------NLGRCIFCGRC 81
Cdd:PRK12576  135 KAEHRLKPEDQKElwkfaQCIWCGLCVSACPVVAIDPEfLGPAAHAKGYRFladprdtiteermkilidSSWRCTYCYSC 214


                  ....*
gi 1730651616  82 EEVCP 86
Cdd:PRK12576  215 SNVCP 219
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 25-59 1.76e-03

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 35.49  E-value: 1.76e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1730651616  25 VDKNFRGKPEHNPQQCIGCAACVNACPSNALTVET 59
Cdd:COG1143    22 EDGEPGKVYVIDPDKCIGCGLCVEVCPTGAISMTP 56
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 31-58 2.29e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 35.03  E-value: 2.29e-03
                          10        20
                  ....*....|....*....|....*...
gi 1730651616  31 GKPEHNPQQCIGCAACVNACPSNALTVE 58
Cdd:COG2221    37 GKLVIDEEKCIGCGACIRVCPTGAIKGE 64
Fer4_8 pfam13183
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 39-86 2.77e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 433017 [Multi-domain]  Cd Length: 64  Bit Score: 34.98  E-value: 2.77e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  39 QCIGCAACVNACPSNALTVETD-------LAANQLGWQFNLG------RCIFCGRCEEVCP 86
Cdd:pfam13183   1 RCIRCGACLAACPVYLVTGGRFpgdprggAAALLGRLEALEGlaeglwLCTLCGACTEVCP 61
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 33-58 3.09e-03

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 36.07  E-value: 3.09e-03
                          10        20
                  ....*....|....*....|....*.
gi 1730651616  33 PEHNPQQCIGCAACVNACPSNALTVE 58
Cdd:cd10564   112 PELDADACTGCGACVSVCPVGAITLT 137
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 37-95 3.13e-03

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 36.85  E-value: 3.13e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1730651616  37 PQQCIGC--AACVNACPSNALTVETDlAANQlgwqFNLGRCIFCGRCEEVCPTAAIRLSQE 95
Cdd:COG0437    57 PVLCNHCddPPCVKVCPTGATYKRED-GIVL----VDYDKCIGCRYCVAACPYGAPRFNPE 112
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 44-95 3.60e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 36.00  E-value: 3.60e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1730651616  44 AACVNACPSNALTVETDLAAnqlgwQFNLGRCIFCGRCEEVCPTAAIRLSQE 95
Cdd:cd16371    60 PACVKVCPTGAITKREDGIV-----VVDQDKCIGCGYCVWACPYGAPQYNPE 106
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
13-95 4.26e-03

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 35.31  E-value: 4.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  13 TATHSYPLEPMPVDK---NFRG-----KPEHNPQQCIGCAACVNACPSNALTVETDlaanqlGW-QFNLGRCIFCGRCEE 83
Cdd:PRK09623   18 KSVDEYPEAPISLGTtlsNFTGdwrtfMPVVDESKCVKCYICWKFCPEPAIYIKED------GYvAIDYDYCKGCGICAN 91

                          90
                  ....*....|..
gi 1730651616  84 VCPTAAIRLSQE 95
Cdd:PRK09623   92 ECPTKAITMVKE 103
NapF COG1145
Ferredoxin [Energy production and conversion];
34-63 4.42e-03

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 36.62  E-value: 4.42e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 1730651616  34 EHNPQQCIGCAACVNACPSNALTVETDLAA 63
Cdd:COG1145   209 VVDPDKCIGCGACVKVCPVGAISLEPKEIE 238
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
30-63 4.80e-03

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 34.32  E-value: 4.80e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1730651616  30 RGKPEHNPQQCIGCAACVNACPSNALTVETDLAA 63
Cdd:COG2768    32 DGKAVIDPEKCIGCGACIEVCPVGAIKIEWEEDE 65
PRK07570 PRK07570
succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated
 40-105 4.96e-03

succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated


Pssm-ID: 181038 [Multi-domain]  Cd Length: 250  Bit Score: 36.35  E-value: 4.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  40 CIGCAACVNACP--SNALTVETDLAanqlgwQFNL------------------------GRCIFCGRCEEVCP-----TA 88
Cdd:PRK07570  159 CIGCGACVAACPngSAMLFTGAKVS------HLALlpqgqperarrvramvaqmdeegfGNCTNTGECEAVCPkgislEN 232

                          90
                  ....*....|....*..
gi 1730651616  89 AIRLSQEYELAVWKKED 105
Cdd:PRK07570  233 IARMNREYLRASFRGRD 249
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 74-104 5.20e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 36.38  E-value: 5.20e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1730651616  74 RCIFCGRCEEVCPTAAIRLSQEYelAVWKKE 104
Cdd:NF038196  186 KCIGCGICAKVCPVNNIEMEDGK--PVWGHN 214
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 36-90 5.39e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 35.39  E-value: 5.39e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  36 NPQQCIGCAACVNACpSNALTVETD-----LAANQLGWQFNLGRCIFCGRCEEVCPTAAI 90
Cdd:cd16372     6 DPEKCIGCLQCEEAC-SKTFFKEEDrekscIRITETEGGYAINVCNQCGECIDVCPTGAI 64
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
40-61 5.97e-03

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 36.54  E-value: 5.97e-03
                          10        20
                  ....*....|....*....|..
gi 1730651616  40 CIGCAACVNACPSNALTVETDL 61
Cdd:COG4624   122 CISCGQCVAVCPFGAITEKSDI 143
Fer4_6 pfam12837
4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to ...
 32-55 7.95e-03

4Fe-4S binding domain; This superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 432822 [Multi-domain]  Cd Length: 24  Bit Score: 32.59  E-value: 7.95e-03
                          10        20
                  ....*....|....*....|....
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNAL 55
Cdd:pfam12837   1 VVEVDPDKCIGCGRCVVVCPYGAI 24
PRK10194 PRK10194
ferredoxin-type protein NapF;
32-62 8.48e-03

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 35.38  E-value: 8.48e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1730651616  32 KPEHNPQQCIGCAACVNACPSNALTVETDLA 62
Cdd:PRK10194  132 QPQLNSQLCNGCGACAASCPVSAITAEYLHA 162
napH PRK09477
quinol dehydrogenase membrane component; Provisional
 35-93 8.57e-03

quinol dehydrogenase membrane component; Provisional


Pssm-ID: 236535 [Multi-domain]  Cd Length: 271  Bit Score: 35.65  E-value: 8.57e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  35 HNPQQCIGCAACVNACPSNALtVETDLAANQLGWQFNLGRCIFCGRCEEVCPTAAIRLS 93
Cdd:PRK09477  205 HDRQKCTRCMDCFHVCPEPQV-LRPPLKGKQSPSQVTSGDCITCGRCIDVCSEDVFNFT 262
PRK10882 PRK10882
hydrogenase 2 operon protein HybA;
35-90 8.77e-03

hydrogenase 2 operon protein HybA;


Pssm-ID: 236786 [Multi-domain]  Cd Length: 328  Bit Score: 35.80  E-value: 8.77e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1730651616  35 HNPQQCIGCAACVNACPSNALTVETDLAANQlgwqfnLGRCIFCGR-------------CEEVCPTAAI 90
Cdd:PRK10882  140 YDKDVCTGCRYCMVACPFNVPKYDYNNPFGA------IHKCELCNQkgverldkgglpgCVEVCPTGAV 202
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
40-59 8.84e-03

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 35.81  E-value: 8.84e-03
                          10        20
                  ....*....|....*....|
gi 1730651616  40 CIGCAACVNACPSNALTVET 59
Cdd:COG0348   238 CINCGRCIDACPKDAIRFSS 257
QueG COG1600
Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and ...
 22-86 9.31e-03

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and biogenesis]; Epoxyqueuosine reductase QueG (queuosine biosynthesis) is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441208 [Multi-domain]  Cd Length: 345  Bit Score: 35.95  E-value: 9.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1730651616  22 PMPVDknfrgkpEHNPQQCIGCAACVNACPSNA---------------LTVETDlaaNQLGWQF--NLGRCIF-CGRCEE 83
Cdd:COG1600   175 ELPPD-------EPVEDHCGSCTRCLDACPTGAivapyvldarrcisyLTIELK---GPIPEELrpKMGNRIYgCDDCQD 244


                  ...
gi 1730651616  84 VCP 86
Cdd:COG1600   245 VCP 247
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 36-91 9.86e-03

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 35.44  E-value: 9.86e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1730651616  36 NPQQCIGCAACVNACPSN--ALTVETDLAAnqlgwqfnlgRCIFC---------GRCEEVCPTAAIR 91
Cdd:cd10560   106 QPDICNGCGYCVAACPFGviDRNEETGRAH----------KCTLCydrlkdglePACAKACPTGSIQ 162
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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