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Conserved domains on  [gi|2095302237|gb|UAS75984|]
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iron ABC transporter permease [Staphylococcus pseudintermedius]

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 23-327 3.88e-88

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 266.55  E-value: 3.88e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  23 SLMIGNTLVSLPQLIQALFHFDGQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVNAGAVFFI 102
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 103 VTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGmFKQARFTPQRVILAGASISMLFTAFTQGIL-IMNETNLQGLLFWL 181
Cdd:COG0609    81 VLAIVLGGGLSALGLPLAAFLGALLAALLVYLLA-RRGGGLSPLRLVLAGVAVSALFSALTSLLLlLADPEQLRSIVFWL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 182 SGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGSIIFVGL 261
Cdd:COG0609   160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2095302237 262 IIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMKKG 327
Cdd:COG0609   240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 23-327 3.88e-88

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 266.55  E-value: 3.88e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  23 SLMIGNTLVSLPQLIQALFHFDGQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVNAGAVFFI 102
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 103 VTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGmFKQARFTPQRVILAGASISMLFTAFTQGIL-IMNETNLQGLLFWL 181
Cdd:COG0609    81 VLAIVLGGGLSALGLPLAAFLGALLAALLVYLLA-RRGGGLSPLRLVLAGVAVSALFSALTSLLLlLADPEQLRSIVFWL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 182 SGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGSIIFVGL 261
Cdd:COG0609   160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2095302237 262 IIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMKKG 327
Cdd:COG0609   240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 16-326 2.11e-73

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 228.95  E-value: 2.11e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  16 LVIVSFLSLMIGNTLVSLPQLIQALFHFDgQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVN 95
Cdd:pfam01032   2 LLLLILLSLFIGAVKISPSDVFSALLGGD-DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  96 AGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGmFKQARFTPQRVILAGASISMLFTAFTQGILI-MNETNL 174
Cdd:pfam01032  81 SGAALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLS-RGRGGASPLRLILAGIAVSALLSALTSLLLLlLNPEAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 175 QGLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAG 254
Cdd:pfam01032 160 QSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVG 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2095302237 255 SIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMKK 326
Cdd:pfam01032 240 PIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
16-326 2.49e-54

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 180.67  E-value: 2.49e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  16 LVIVSFLSLMIGNTLVSLPQLIQALFHFDGQNDVhTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVN 95
Cdd:PRK10441   20 LIIATALSLLIGAKSLPASVVLEALSGTCQSADC-TIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  96 AGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGMFKQARFTPQRVILAGASISMLFTAFTQGILIMNETNLQ 175
Cdd:PRK10441   99 AGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYD 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 176 GLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGS 255
Cdd:PRK10441  179 QLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGP 258

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2095302237 256 IIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIrPLELPVGIITGILGALVLIYLMKK 326
Cdd:PRK10441  259 IAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLV-PGELRVSVVSAFIGAPVLIFLVRR 328
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-324 9.57e-42

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 145.78  E-value: 9.57e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  61 TIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVNAGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGMFKq 140
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRG- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 141 aRFTPQRVILAGASISMLFTAFTQGILIMNETNLQGLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTS 220
Cdd:cd06550    80 -GLSPSKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 221 DEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGSIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVI 300
Cdd:cd06550   159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                         250       260
                  ....*....|....*....|....
gi 2095302237 301 IrPLELPVGIITGILGALVLIYLM 324
Cdd:cd06550   239 L-PSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 23-327 3.88e-88

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 266.55  E-value: 3.88e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  23 SLMIGNTLVSLPQLIQALFHFDGQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVNAGAVFFI 102
Cdd:COG0609     1 SLSLGAVPISLSDVLRALLGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 103 VTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGmFKQARFTPQRVILAGASISMLFTAFTQGIL-IMNETNLQGLLFWL 181
Cdd:COG0609    81 VLAIVLGGGLSALGLPLAAFLGALLAALLVYLLA-RRGGGLSPLRLVLAGVAVSALFSALTSLLLlLADPEQLRSIVFWL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 182 SGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGSIIFVGL 261
Cdd:COG0609   160 MGSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGL 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2095302237 262 IIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMKKG 327
Cdd:COG0609   240 VVPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRR 305
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 16-326 2.11e-73

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 228.95  E-value: 2.11e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  16 LVIVSFLSLMIGNTLVSLPQLIQALFHFDgQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVN 95
Cdd:pfam01032   2 LLLLILLSLFIGAVKISPSDVFSALLGGD-DSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGIS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  96 AGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGmFKQARFTPQRVILAGASISMLFTAFTQGILI-MNETNL 174
Cdd:pfam01032  81 SGAALGAVLAILLGGSLSLFALPLAAFIGALLAALLVYFLS-RGRGGASPLRLILAGIAVSALLSALTSLLLLlLNPEAL 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 175 QGLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAG 254
Cdd:pfam01032 160 QSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVG 239

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2095302237 255 SIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMKK 326
Cdd:pfam01032 240 PIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 11-324 6.64e-55

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 182.24  E-value: 6.64e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  11 IASACLVIVSFLSLMIGNTLVSLPQLIQALFhfdGQND--VHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVAS 88
Cdd:COG4779    28 VLLLLLLALAVLALTLGDYPLSPGDVLRALL---GEGDpgASFVVLELRLPRALAALLVGAALGLSGAIFQSLTRNPLAS 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  89 PGLFGVNAGAVFFIVTGVTLIRVHSFeALVVMAFVGAILVTILVVGLGMfkQARFTPQRVILAGASISMLFTAFTQGILI 168
Cdd:COG4779   105 PDIIGITAGASAGAVAAIVVLGGSGL-AVALGALAGGLATALLVYLLAW--RGGVSGYRLILVGIGVSAMLTAVNSYLLT 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 169 M-NETNLQGLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAG 247
Cdd:COG4779   182 RaDLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAVALAA 261

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2095302237 248 SSVALAGSIIFVGLIIPNIAKLILPPRYQLLIPyTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLM 324
Cdd:COG4779   262 VATAAAGPIAFVALAAPQIARRLTRSPGPPLLP-SALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLL 337
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
16-326 2.49e-54

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 180.67  E-value: 2.49e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  16 LVIVSFLSLMIGNTLVSLPQLIQALFHFDGQNDVhTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVN 95
Cdd:PRK10441   20 LIIATALSLLIGAKSLPASVVLEALSGTCQSADC-TIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVN 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  96 AGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGMFKQARFTPQRVILAGASISMLFTAFTQGILIMNETNLQ 175
Cdd:PRK10441   99 AGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYD 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 176 GLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGS 255
Cdd:PRK10441  179 QLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGP 258

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2095302237 256 IIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIrPLELPVGIITGILGALVLIYLMKK 326
Cdd:PRK10441  259 IAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLV-PGELRVSVVSAFIGAPVLIFLVRR 328
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
9-324 1.68e-53

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 185.81  E-value: 1.68e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237   9 LFIASACLVIVSFLSLMIGNTLVSLPQLIQALFHFDGQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVAS 88
Cdd:PRK10577   14 ALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVLRNPLAS 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  89 PGLFGVNAGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGMFKqaRFTPQRVILAGASISMLFTAFTQGILI 168
Cdd:PRK10577   94 PTTLGVAAGAQLALVLATLFAPALLALASQLAAFAGGLLAAALVFALAGGK--RLSPLRLVLAGMVVSLYLGALTTLLLL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 169 MNETNLQGLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGS 248
Cdd:PRK10577  172 FNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAA 251

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2095302237 249 SVALAGSIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPL--ELPVGIITGILGALVLIYLM 324
Cdd:PRK10577  252 VVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGgeLLPTGAVTALIGAPLLLWLL 329
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
38-326 4.37e-49

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 166.79  E-value: 4.37e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  38 QALFHFDGQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVNAGAVFFIVTGVTLIRVH-SFEA 116
Cdd:PRK11228   32 NALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSPTPfAGYS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 117 LVVMAFVGAILVTILVVGLGMFKQARFTPQRVILAGASISMLFTAFTQGILIMNETNLQGLLFWLSGSVS---LRNIWDI 193
Cdd:PRK11228  112 LAFIAACGGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRITLLLAEDHAYGIFYWLAGGVSharWQEVWQL 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 194 PWMIVIILLFLIagfFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGSIIFVGLIIPNIAKLILPP 273
Cdd:PRK11228  192 LPFVVTAVPVVL---LLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGY 268

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2095302237 274 RYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMKK 326
Cdd:PRK11228  269 DQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLARR 321
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
11-327 3.27e-48

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 171.56  E-value: 3.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  11 IASACLVIVSFLSLMIGNTLVSLPQLIQALFHFdgqndvhtlVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPG 90
Cdd:PRK10577  360 ALGLLLLLALVVALSFGRDAHGWNWLSGQLLDA---------LLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPE 430

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  91 LFGVNAGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGmfKQARFTPQRVILAGASISMLFTAFTQGILIMN 170
Cdd:PRK10577  431 VLGISSGAGLGVVLALFLVPGAGFGWLLAAALLGALAALALILLLA--RRGGFAPERLLLTGIALSALFTALIQLLLASG 508

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 171 ETNLQGLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSV 250
Cdd:PRK10577  509 DPRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAAT 588

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2095302237 251 ALAGSIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMKKG 327
Cdd:PRK10577  589 ATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRS 665
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 8-326 2.34e-42

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 149.34  E-value: 2.34e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237   8 HLFIASACLVIVSFLSLMIGNTLVSLPQLIQALfhfdgqndVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVA 87
Cdd:PRK03784   17 WLLGLSVLLLLALLLSLCAGEQWISPGDWLSPR--------GELFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  88 SPGLFGVNAGAVFFIVTGVTLIR-VHSFEALVVMAFVGAILVTILVvgLGMFKQARFTPQRVILAGASISMLFTAF-TQG 165
Cdd:PRK03784   89 EPGLLGVSNGAGVALVAAVLLGQgLLPPWALSLCAIAGALLITLIL--LRFARRHRLSTSRLLLAGVALGIICSALmTWA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 166 ILIMNETNLQGLLFWLSGSVSLRNiWDIPWMIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVL 245
Cdd:PRK03784  167 VYFSTSLDLRQLMYWMMGGFGGVD-WRQSWLMLALLPVLIWLCCQGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWL 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 246 AGSSVALAGSIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLMK 325
Cdd:PRK03784  246 VGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLADIVARLALASAELPIGVVTATLGAPVFIWLLL 325


                  .
gi 2095302237 326 K 326
Cdd:PRK03784  326 R 326
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-324 9.57e-42

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 145.78  E-value: 9.57e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  61 TIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVNAGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGMFKq 140
Cdd:cd06550     1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSNYALGAFAFAGALAIALLVLLLASRG- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 141 aRFTPQRVILAGASISMLFTAFTQGILIMNETNLQGLLFWLSGSVSLRNIWDIPWMIVIILLFLIAGFFMAPHLNILMTS 220
Cdd:cd06550    80 -GLSPSKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 221 DEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGSIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVI 300
Cdd:cd06550   159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                         250       260
                  ....*....|....*....|....
gi 2095302237 301 IrPLELPVGIITGILGALVLIYLM 324
Cdd:cd06550   239 L-PSELPVGPVTALLGAPYFLYLL 261
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
4-324 1.51e-37

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 136.33  E-value: 1.51e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237   4 KPIHHLFIASACLVIVSFLSLMIGNTLVSLPQLIQAlFHFDGQNdvHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTR 83
Cdd:PRK09777    1 MKIALVIFITLALAGCALLSLRMGVIPLPWRALLTD-WQAGDEH--YYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVR 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  84 NAVASPGLFGVNAGAVFFIVTGVTLIRVHSFEALVVMAFVGAILVTILVVGLGMFKQarftPQRVILAGASISMLFTAFT 163
Cdd:PRK09777   78 NPLASPDILGVNHAASLASVGALLLFPSLPVMWLPLLAFIGGMAGLILLKMLAGTHQ----PMKLALTGVALSALWASLT 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 164 QGILIMNETNLQGLLFWLSGSVSLRNiWD-----IPWMIVIILLfliaGFFMAPHLNILMTSDEIATGLGQNVKRIKWVI 238
Cdd:PRK09777  154 DYLMLSRPQDINNALLWLTGSLWGRD-WSfvkvaLPWLILLLPL----SLSFCRDLDLLALGDARATTLGVSVPHTQFWA 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 239 VLMISVLAGSSVALAGSIIFVGLIIPNIAKLILPPRYQLLIPYTALLGSCLMISADIVARVIIRPLELPVGIITGILGAL 318
Cdd:PRK09777  229 LLLAVALTATGVAACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAP 308


                  ....*.
gi 2095302237 319 VLIYLM 324
Cdd:PRK09777  309 WFFWLL 314
btuC PRK09535
cobalamin ABC transporter permease BtuC;
39-326 7.00e-34

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 127.56  E-value: 7.00e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  39 ALFHFDGQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVASPGLFGVNAGAVFFIVTGVTLIRVHSFEaLV 118
Cdd:PRK09535   77 SPFSFAVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFG-LQ 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 119 VMAFVGAiLVTILVVGLGMFKQARFTPQRVILAGASISMLFTAFTQGILIMNETNLQGLLFWLSGSVSLRNIWDIPWMIV 198
Cdd:PRK09535  156 AAAFAGA-LVAAFGVYAIATENGRTPVATLLLAGVAVQTFLGAVISYLLLHSGESLRRAVYWLMGHLHGSTWSDVEVALP 234

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 199 IILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVLAGSSVALAGSIIFVGLIIPNIAKLILPPRYQLL 278
Cdd:PRK09535  235 VVVVGFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRIL 314

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2095302237 279 IPYTALLGSCLMISADIVARViiRPLELPVGIITGILGALVLIYLMKK 326
Cdd:PRK09535  315 LPTSALAGASFLVATDTVARS--GPAEVPVGIVTAALGAPFFLYLLRT 360
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
9-324 3.16e-26

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 106.33  E-value: 3.16e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237   9 LFIASACLVIvSFLSLMIGNTLVSLPQLIQALFHfDGQNDVHTLVTGSRASRTIIALLTGAALAVAGLFMQVLTRNAVAS 88
Cdd:PRK10440   13 LLLLAACVAA-GLWGLRSGAVTLETSQVFAALMG-DAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGS 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237  89 PGLFGVNAGAVFFIVTGVTLIRVHSFeALVVMAFVGAILvTILVVGLGMFKQARFTpQRVILAGASISMLFTAFTQGILI 168
Cdd:PRK10440   91 PDVMGFNTGAWSGVLVAMVLFGQDLT-AIALAAMAGGIV-TSLLVWLLAWRNGIDT-FRLIIIGIGVRAMLVAFNTWLLL 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302237 169 MN--ETNLQGLLfWLSGSVSLRNiWDIPW-MIVIILLFLIAGFFMAPHLNILMTSDEIATGLGQNVKRIKWVIVLMISVL 245
Cdd:PRK10440  168 KAslETALTAGL-WNAGSLNGLT-WAKTSpSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVL 245

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2095302237 246 AGSSVALAGSIIFVGLIIPNIAKLILPPRYQLLIPyTALLGSCLMISADIVARVIIRPLELPVGIITGILGALVLIYLM 324
Cdd:PRK10440  246 TAAATALAGPISFIALVAPHIARRLSGTARWGLTQ-AALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLL 323
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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