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Conserved domains on  [gi|2095302243|gb|UAS75990|]
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monovalent cation/H+ antiporter complex subunit F [Staphylococcus pseudintermedius]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12599 super family cl09154
putative monovalent cation/H+ antiporter subunit F; Reviewed
 1-97 5.36e-34

putative monovalent cation/H+ antiporter subunit F; Reviewed


The actual alignment was detected with superfamily member PRK12657:

Pssm-ID: 471859  Cd Length: 100  Bit Score: 112.55  E-value: 5.36e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243   1 MIEALTQFLLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSV 80
Cdd:PRK12657    1 MIQTITHIMIISALIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSV 80

                          90
                  ....*....|....*..
gi 2095302243  81 TISRFIEGGNVFHGDDK 97
Cdd:PRK12657   81 SISRFIGGGHVFNGNNK 97
 
Name Accession Description Interval E-value
PRK12657 PRK12657
putative monovalent cation/H+ antiporter subunit F; Reviewed
 1-97 5.36e-34

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 183657  Cd Length: 100  Bit Score: 112.55  E-value: 5.36e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243   1 MIEALTQFLLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSV 80
Cdd:PRK12657    1 MIQTITHIMIISALIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSV 80

                          90
                  ....*....|....*..
gi 2095302243  81 TISRFIEGGNVFHGDDK 97
Cdd:PRK12657   81 SISRFIGGGHVFNGNNK 97
MnhF COG2212
Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];
5-88 4.89e-15

Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441814  Cd Length: 84  Bit Score: 63.97  E-value: 4.89e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243  5 LTQFLLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISR 84
Cdd:COG2212    1 MMTTVLLIALALLALALLLALYRLIRGPTLADRVLALDTLGTNAVALLALLGILTGRPLYLDVALVLALLGFVGTVAFAR 80


                 ....
gi 2095302243 85 FIEG 88
Cdd:COG2212   81 FLER 84
MrpF_PhaF pfam04066
Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF ...
 36-87 8.27e-07

Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF family are predicted to be an integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation. It is also involved in symbiosis in Rhizobium meliloti. MrpF is part of a Na+/H+ antiporter complex, also involved in pH homeostasis. MrpF is thought to be an efflux system for Na+ and cholate. The Mrp system in Bacilli may also have primary energization capacities.


Pssm-ID: 461156  Cd Length: 52  Bit Score: 42.00  E-value: 8.27e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 2095302243 36 DRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISRFIE 87
Cdd:pfam04066  1 DRVVALDTLGTNIVALLALLAILTGRPAYLDVALVLALLGFVGTVAFARFLE 52
 
Name Accession Description Interval E-value
PRK12657 PRK12657
putative monovalent cation/H+ antiporter subunit F; Reviewed
 1-97 5.36e-34

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 183657  Cd Length: 100  Bit Score: 112.55  E-value: 5.36e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243   1 MIEALTQFLLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSV 80
Cdd:PRK12657    1 MIQTITHIMIISALIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSV 80

                          90
                  ....*....|....*..
gi 2095302243  81 TISRFIEGGNVFHGDDK 97
Cdd:PRK12657   81 SISRFIGGGHVFNGNNK 97
PRK12600 PRK12600
Na(+)/H(+) antiporter subunit F1;
7-96 3.98e-18

Na(+)/H(+) antiporter subunit F1;


Pssm-ID: 183617  Cd Length: 94  Bit Score: 71.88  E-value: 3.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243  7 QFLLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISRFI 86
Cdd:PRK12600   3 NIILSIALIIVAISMLLMLIRVIKGPTLADRVVALDAIGINLIAIIALFSILLDTKAYLEVILLIGILAFIGTAAFSKFI 82

                         90
                 ....*....|
gi 2095302243 87 EGGNVFHGDD 96
Cdd:PRK12600  83 EKGKVIERDR 92
MnhF COG2212
Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];
5-88 4.89e-15

Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441814  Cd Length: 84  Bit Score: 63.97  E-value: 4.89e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243  5 LTQFLLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISR 84
Cdd:COG2212    1 MMTTVLLIALALLALALLLALYRLIRGPTLADRVLALDTLGTNAVALLALLGILTGRPLYLDVALVLALLGFVGTVAFAR 80


                 ....
gi 2095302243 85 FIEG 88
Cdd:COG2212   81 FLER 84
PRK12599 PRK12599
putative monovalent cation/H+ antiporter subunit F; Reviewed
 3-92 1.21e-13

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 237148  Cd Length: 91  Bit Score: 60.69  E-value: 1.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243  3 EALTQFLLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTI 82
Cdd:PRK12599   1 MTLLEDAFLIAAVLLVLALILSLYRVILGPTLPDRVVALDTLNTITVGIIAVLAAATGRPLYLDIAIVYALLSFLGTVAI 80

                         90
                 ....*....|
gi 2095302243 83 SRFIEGGNVF 92
Cdd:PRK12599  81 AKYLVGRGGV 90
PRK06161 PRK06161
putative monovalent cation/H+ antiporter subunit F; Reviewed
 13-91 7.18e-10

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 180435  Cd Length: 89  Bit Score: 51.00  E-value: 7.18e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2095302243 13 ALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISRFIEGGNV 91
Cdd:PRK06161   9 AQVALALAMLLALWRLLRGPRAQDRILALDTLYINAILLLLVFGIRLGSTIYFEAALLIALLGFVSTVALAKFLLRGEV 87
PRK12604 PRK12604
putative monovalent cation/H+ antiporter subunit F; Reviewed
 14-89 5.14e-08

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 183619  Cd Length: 84  Bit Score: 45.91  E-value: 5.14e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2095302243 14 LVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISRFIEGG 89
Cdd:PRK12604   8 LALIAIATLLSMYRVFRGPTTVDRLVAVDIMTTITTGLMVLFALYYKRMIFLDVALVYAILAFVGVIAFARYLEGG 83
PRK07948 PRK07948
putative monovalent cation/H+ antiporter subunit F; Reviewed
 9-85 1.44e-07

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 181179  Cd Length: 86  Bit Score: 45.06  E-value: 1.44e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2095302243  9 LLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISRF 85
Cdd:PRK07948   4 VLTIAAVFLSLAAILTTYRILAGPNSLDRLVALDTLVAVTMCALATWAAWTLDTTVTNAMTALALIGFIGSVSVARF 80
MrpF_PhaF pfam04066
Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF ...
 36-87 8.27e-07

Multiple resistance and pH regulation protein F (MrpF / PhaF); Members of the PhaF / MrpF family are predicted to be an integral membrane proteins with three transmembrane regions, involved in regulation of pH. PhaF is part of a potassium efflux system involved in pH regulation. It is also involved in symbiosis in Rhizobium meliloti. MrpF is part of a Na+/H+ antiporter complex, also involved in pH homeostasis. MrpF is thought to be an efflux system for Na+ and cholate. The Mrp system in Bacilli may also have primary energization capacities.


Pssm-ID: 461156  Cd Length: 52  Bit Score: 42.00  E-value: 8.27e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 2095302243 36 DRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISRFIE 87
Cdd:pfam04066  1 DRVVALDTLGTNIVALLALLAILTGRPAYLDVALVLALLGFVGTVAFARFLE 52
PRK08381 PRK08381
putative monovalent cation/H+ antiporter subunit F; Reviewed
 9-88 5.51e-03

putative monovalent cation/H+ antiporter subunit F; Reviewed


Pssm-ID: 169414  Cd Length: 87  Bit Score: 33.17  E-value: 5.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302243  9 LLSSALVIFAISLVVVLFRLVKGPTTADRVVAFDAMSAILMSTVGVLSLLFETFSFLDSVLLIAIISFLSSVTISRFIEG 88
Cdd:PRK08381   6 LLVAGFWILLFTALLASYRVIFGPTLADRIVGLNTITTKVVGIIAILSVLWEEYYLLDLAIVLLMVNAVGGLILAKYMER 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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