NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2095302246|gb|UAS75993|]
View 

Na+/H+ antiporter Mnh2 subunit C [Staphylococcus pseudintermedius]

Protein Classification

Na(+)/H(+) antiporter subunit C; NADH-quinone oxidoreductase subunit NuoK( domain architecture ID 10014041)

Na(+)/H(+) antiporter subunit C (MrpC) is part of a heterooligomeric complex together with MrpA, MrpB, MrpD, MrpE, MrpF and MrpG, which is involved in resistance to Na(+) and excretion of Li(+) and Na(+)| NADH-quinone oxidoreductase subunit K (NuoK) is part of the membrane domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-114 2.13e-51

putative monovalent cation/H+ antiporter subunit C; Reviewed


:

Pssm-ID: 183660  Cd Length: 114  Bit Score: 157.59  E-value: 2.13e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTPQKTEPLIVGSNQNFVDPLLQAIVLTAIVI 80
Cdd:PRK12660    1 MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2095302246  81 GFAITAFLLVLVYRTFKVTKEDEIDVLTGGEEDE 114
Cdd:PRK12660   81 GFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK 114
 
Name Accession Description Interval E-value
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-114 2.13e-51

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 183660  Cd Length: 114  Bit Score: 157.59  E-value: 2.13e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTPQKTEPLIVGSNQNFVDPLLQAIVLTAIVI 80
Cdd:PRK12660    1 MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2095302246  81 GFAITAFLLVLVYRTFKVTKEDEIDVLTGGEEDE 114
Cdd:PRK12660   81 GFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK 114
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-112 4.32e-34

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 113.67  E-value: 4.32e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGeYTPQKTEPLIVG--SNQNFVDPLLQAIVLTAI 78
Cdd:COG1006     1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMG-GLTGGAPPILGEgpPAAPYADPLPQALVLTAI 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2095302246  79 VIGFAITAFLLVLVYRTFKVTKEDEIDVLTGGEE 112
Cdd:COG1006    80 VIGFAVTAFLLALAYRIYQLYGTDDVDELREDER 113
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 1-105 1.50e-21

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 81.78  E-value: 1.50e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTpQKTEPLIVGSNQNFVDPLLQAIVLTAIVI 80
Cdd:TIGR00941   1 MESIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLE-NKAPPILTLPVGPYVDPLPQALILTAIVI 79

                          90       100
                  ....*....|....*....|....*
gi 2095302246  81 GFAITAFLLVLVYRTFKVTKEDEID 105
Cdd:TIGR00941  80 GFATTALFLVVALRAYQVAGTDDVE 104
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-112 7.20e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 64.51  E-value: 7.20e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   4 ILLIVIGFLVFIGTYMVL-SKNLIRIVIGIAIFTHAGNLIIMSMGEYTpqkteplivgsnqnfVDPLLQAIVLTAIVIGF 82
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLT---------------ADPLPQALILTAIVIAA 65

                          90       100       110
                  ....*....|....*....|....*....|
gi 2095302246  83 AITAFLLVLVYRTFKVTKEDEIDVLTGGEE 112
Cdd:pfam00420  66 AEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-114 2.13e-51

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 183660  Cd Length: 114  Bit Score: 157.59  E-value: 2.13e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTPQKTEPLIVGSNQNFVDPLLQAIVLTAIVI 80
Cdd:PRK12660    1 MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVI 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2095302246  81 GFAITAFLLVLVYRTFKVTKEDEIDVLTGGEEDE 114
Cdd:PRK12660   81 GFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK 114
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-112 4.32e-34

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 113.67  E-value: 4.32e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGeYTPQKTEPLIVG--SNQNFVDPLLQAIVLTAI 78
Cdd:COG1006     1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMG-GLTGGAPPILGEgpPAAPYADPLPQALVLTAI 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2095302246  79 VIGFAITAFLLVLVYRTFKVTKEDEIDVLTGGEE 112
Cdd:COG1006    80 VIGFAVTAFLLALAYRIYQLYGTDDVDELREDER 113
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-114 5.87e-33

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 181497  Cd Length: 113  Bit Score: 110.82  E-value: 5.87e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTpQKTEPLIVGSNQNFVDPLLQAIVLTAIVI 80
Cdd:PRK08600    1 MEILMIIVIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTMGGLK-KGAVPILGEGVTSYVDPLPQALILTAIVI 79

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2095302246  81 GFAITAFLLVLVYRTFKVTKEDEIDVLTGGEEDE 114
Cdd:PRK08600   80 SFGVTAFFLVLAYRTYKELGTDNVEQMRGVPEDD 113
PRK07946 PRK07946
putative monovalent cation/H+ antiporter subunit C; Reviewed
 2-105 2.35e-25

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236136  Cd Length: 163  Bit Score: 93.19  E-value: 2.35e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   2 NIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEytpQKTEPLIVGSNQNF----VDPLLQAIVLTA 77
Cdd:PRK07946    4 NLGLLVAIGVLTSAGVYLLLERSLTRMLLGLLLIGNGVNLLILTAGG---PAGNPPILGRTSEYgetmADPLAQAMILTA 80

                          90       100
                  ....*....|....*....|....*...
gi 2095302246  78 IVIGFAITAFLLVLVYRTFKVTKEDEID 105
Cdd:PRK07946   81 IVITMGITAFVLALAYRSYRLTTADEVE 108
PRK12658 PRK12658
Na+/H+ antiporter subunit C;
1-114 3.34e-24

Na+/H+ antiporter subunit C;


Pssm-ID: 183658  Cd Length: 125  Bit Score: 88.97  E-value: 3.34e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTPQkTEPLIVGSNQNFVD----PLLQAIVLT 76
Cdd:PRK12658    1 MEALFAILVGVFFAAAIYLMLSRHIIRILFGLALLGNAVNLLIFTAGRLTRE-VPPLIPAGADVLAEgaanPLPQALILT 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2095302246  77 AIVIGFAITAFLLVLVYRTFKVTKEDEIDVLTGGEEDE 114
Cdd:PRK12658   80 AIVIGFGLLAFLLVLAYRAYQDLGTDDTDEMRVAEPVE 117
PRK12659 PRK12659
Na+/H+ antiporter subunit C;
1-114 4.64e-22

Na+/H+ antiporter subunit C;


Pssm-ID: 183659  Cd Length: 117  Bit Score: 83.56  E-value: 4.64e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTPqKTEPLIVGSNQNFV----DPLLQAIVLT 76
Cdd:PRK12659    1 MEFLLAIVVGGLYAAGIYMMLRRSIVKLVIGLILLGNAANLLIFTVGRLTR-GAPPLVPEGATAPAgpvaDPLPQALILT 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2095302246  77 AIVIGFAITAFLLVLVYRTFKVTKEDEIDVLTGGEEDE 114
Cdd:PRK12659   80 AIVIGFGVQAFAIVLIKRAYQVVGTDDLDEMKTTDTLS 117
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 1-105 1.50e-21

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 81.78  E-value: 1.50e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTpQKTEPLIVGSNQNFVDPLLQAIVLTAIVI 80
Cdd:TIGR00941   1 MESIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLE-NKAPPILTLPVGPYVDPLPQALILTAIVI 79

                          90       100
                  ....*....|....*....|....*
gi 2095302246  81 GFAITAFLLVLVYRTFKVTKEDEID 105
Cdd:TIGR00941  80 GFATTALFLVVALRAYQVAGTDDVE 104
PRK09094 PRK09094
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-114 1.02e-19

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236377  Cd Length: 114  Bit Score: 77.23  E-value: 1.02e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYT---PQKTEPLIVGSNQNFVDPLLQAIVLTA 77
Cdd:PRK09094    1 MELVLALAIGVLTASGVWLLLRPRTFQVILGLSLLSYAVNLFIFAMGRLRvgaPPVLQPGVPVDLANYTDPLPQALVLTA 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2095302246  78 IVIGFAITAFLLVLVYRTFKVTKEDEIDvltgGEEDE 114
Cdd:PRK09094   81 IVIGFAMTALFLVVALASRGLTGTDHVD----GREPE 113
PRK07375 PRK07375
Na+/H+ antiporter subunit C;
1-105 1.98e-19

Na+/H+ antiporter subunit C;


Pssm-ID: 236004  Cd Length: 112  Bit Score: 76.46  E-value: 1.98e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   1 MNIILLIVIGFLVFIGTY-MVLSKNLIRIVIGIAIFTHAGNLIIMSMGeYTPQKTEPLIVGSNQ-NFVDPLLQAIVLTAI 78
Cdd:PRK07375    1 MQLMIYALAIALLVIGLYgLIFKRNLLKKIIGLDVFQTGVNLFYIAIG-YRSGGGVPILSPSGFtTYADPLPQALVLTAI 79

                          90       100       110
                  ....*....|....*....|....*....|
gi 2095302246  79 VIGFAITAFLLVLV---YRTFKVTKEDEID 105
Cdd:PRK07375   80 VIGFATTAVMLALIvklYKDYGTLSESEIE 109
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-112 7.20e-15

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 64.51  E-value: 7.20e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   4 ILLIVIGFLVFIGTYMVL-SKNLIRIVIGIAIFTHAGNLIIMSMGEYTpqkteplivgsnqnfVDPLLQAIVLTAIVIGF 82
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLT---------------ADPLPQALILTAIVIAA 65

                          90       100       110
                  ....*....|....*....|....*....|
gi 2095302246  83 AITAFLLVLVYRTFKVTKEDEIDVLTGGEE 112
Cdd:pfam00420  66 AEAAVGLALLVRIYRTHGTDDVDSLNLLKG 95
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 2-97 7.05e-14

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 63.25  E-value: 7.05e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   2 NIILLIVIGFLVFIGTYMVLSKNLIRIVIGIAIFTHAGNLIIMSMGEYTPQKTePLIVGSNQN----------------- 64
Cdd:PRK12661    3 NFFLSLTIALLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVFEGTKV-PIITEQGHEgsgsgiiyndnltsgil 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 2095302246  65 -----------FVDPLLQAIVLTAIVIGFAITAFLLVLVYRTFK 97
Cdd:PRK12661   82 apivtngpeteFVDPLVQALVLTAIVIGLATTAFILILAYRIYE 125
PRK08389 PRK08389
putative monovalent cation/H+ antiporter subunit C; Reviewed
 12-105 1.04e-08

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236258  Cd Length: 114  Bit Score: 48.96  E-value: 1.04e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246  12 LVFIGTYMVLSK-NLIRIVIGIAIFTHAGNLIIMSMGEYTPQKTEPLIVG-SNQNFVDPLLQAIVLTAIVIGFAITAFLL 89
Cdd:PRK08389   12 LVLIGLYGVLVKkNLLKIIIGLDIMETGVNLLLISIGYVSGRSAPILSEGiTPSNYVDPIPQALVLTAIVIGVSTTALAL 91

                          90
                  ....*....|....*.
gi 2095302246  90 VLVYRTFKVTKEDEID 105
Cdd:PRK08389   92 SVAIKLYEKYGTLNVE 107
PRK08388 PRK08388
putative monovalent cation/H+ antiporter subunit C; Reviewed
 7-97 7.84e-04

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236257  Cd Length: 119  Bit Score: 36.42  E-value: 7.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2095302246   7 IVIGFLVFIGTYMVLSK-NLIRIVIGIAIFTHAGNLIIMSMG---EYTPQKTEPLIVG---SNQNFVDPLLQAIVLTAIV 79
Cdd:PRK08388    7 ITAFLMIALGIYAFLYKrNLIKLILALDLIDSGIHLLLISLGyrmENGLPPTAPIYTGyetLKSPMVGPIPQALVLTSIV 86

                          90
                  ....*....|....*...
gi 2095302246  80 IGFAITAFLLVLVYRTFK 97
Cdd:PRK08388   87 IGVCVLSLAMALTINAYR 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH