NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2216107316|gb|UOC05312|]
View 

hypothetical protein BTT_65650 (plasmid) [Bacillus thuringiensis serovar morrisoni str. 4AA1]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 11465549)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain

CATH:  2.60.40.10
Gene Ontology:  GO:0005515
PubMed:  19576999|9837732|8981327

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
33-447 1.54e-25

Fibronectin type 3 domain [General function prediction only];


:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 109.71  E-value: 1.54e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316  33 TDAYTKWYIKSYSAEATFKGREEGKSYLYGTEVIADLGAEYSVKYLKYYAQGGIDGGYVYFYDEKFQSVFNQDLKTFGAN 112
Cdd:COG3401    10 DAGIAASAAANTAVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 113 GQFDVGKKARYVSVGHSTS---RSPNALKVHSFSVFIDDGKVSDVTDLKAKADINKVELTWKNPVEDGFNGVNIYQDDVL 189
Cdd:COG3401    90 TATGLTTLTGSGSVGGATNtglTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 190 --------------MTTLDKSATSYNVGDLKDNTMYRFKVSSLDGGKVETKGVETSVKTLLdpkkIPPSPVSSLVAEP-T 254
Cdd:COG3401   170 vspdtsataavattSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPT----TPPSAPTGLTATAdT 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 255 DKTVKLIWKKPSDDDLAGFKIL------ENGKKIAEIGlEEEFTVKNLEPLTEYNFGVVAVDKDKNDSSPVN-LSVKTle 327
Cdd:COG3401   246 PGSVTLSWDPVTESDATGYRVYrsnsgdGPFTKVATVT-TTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSNvVSVTT-- 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 328 ekDDVPPHVPSNV-FAKPSNGALIASWDKVSDKDLAGYNVYLDGKKINS-----NLISSTNFSIKNLENNRKYKVQVQAV 401
Cdd:COG3401   323 --DLTPPAAPSGLtATAVGSSSITLSWTASSDADVTGYNVYRSTSGGGTytkiaETVTTTSYTDTGLTPGTTYYYKVTAV 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2216107316 402 DRSGNASELSSPVFGTPDMNTIPLVESKYNLQDVSDGVGNQFWQIW 447
Cdd:COG3401   401 DAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAAS 446
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
33-447 1.54e-25

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 109.71  E-value: 1.54e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316  33 TDAYTKWYIKSYSAEATFKGREEGKSYLYGTEVIADLGAEYSVKYLKYYAQGGIDGGYVYFYDEKFQSVFNQDLKTFGAN 112
Cdd:COG3401    10 DAGIAASAAANTAVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 113 GQFDVGKKARYVSVGHSTS---RSPNALKVHSFSVFIDDGKVSDVTDLKAKADINKVELTWKNPVEDGFNGVNIYQDDVL 189
Cdd:COG3401    90 TATGLTTLTGSGSVGGATNtglTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 190 --------------MTTLDKSATSYNVGDLKDNTMYRFKVSSLDGGKVETKGVETSVKTLLdpkkIPPSPVSSLVAEP-T 254
Cdd:COG3401   170 vspdtsataavattSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPT----TPPSAPTGLTATAdT 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 255 DKTVKLIWKKPSDDDLAGFKIL------ENGKKIAEIGlEEEFTVKNLEPLTEYNFGVVAVDKDKNDSSPVN-LSVKTle 327
Cdd:COG3401   246 PGSVTLSWDPVTESDATGYRVYrsnsgdGPFTKVATVT-TTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSNvVSVTT-- 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 328 ekDDVPPHVPSNV-FAKPSNGALIASWDKVSDKDLAGYNVYLDGKKINS-----NLISSTNFSIKNLENNRKYKVQVQAV 401
Cdd:COG3401   323 --DLTPPAAPSGLtATAVGSSSITLSWTASSDADVTGYNVYRSTSGGGTytkiaETVTTTSYTDTGLTPGTTYYYKVTAV 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2216107316 402 DRSGNASELSSPVFGTPDMNTIPLVESKYNLQDVSDGVGNQFWQIW 447
Cdd:COG3401   401 DAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAAS 446
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 243-311 4.42e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.61  E-value: 4.42e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2216107316  243 PSPVSSLVAEPTDKT-VKLIWKKPSDDDLAGFKI---------LENGKKIAEIGLEEEFTVKNLEPLTEYNFGVVAVDK 311
Cdd:smart00060   1 PSPPSNLRVTDVTSTsVTLSWEPPPDDGITGYIVgyrveyreeGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 334-417 8.70e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.11  E-value: 8.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 334 PHVPSNVFAKP-SNGALIASWDKVSD--KDLAGYNVYL------DGKKINSNLISSTNFSIKNLENNRKYKVQVQAVDRS 404
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDdgGPITGYVVEYrekgsgDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|...
gi 2216107316 405 GNaSELSSPVFGT 417
Cdd:cd00063    81 GE-SPPSESVTVT 92
RGI_lyase pfam18370
Rhamnogalacturonan I lyases beta-sheet domain; This is the beta-sheet domain found in ...
 340-408 2.31e-03

Rhamnogalacturonan I lyases beta-sheet domain; This is the beta-sheet domain found in rhamnogalacturonan (RG) lyases, which are responsible for an initial cleavage of the RG type I (RG-I) region of plant cell wall pectin. Polysaccharide lyase family 11 carrying this domain, such as YesW (EC:4.2.2.23) and YesX (EC:4.2.2.24), cleave glycoside bonds between rhamnose and galacturonic acid residues in RG-I through a beta-elimination reaction. Other family members carrying this domain are hemagglutinin A, lysine gingipain (Kgp) and Chitinase C (EC:3.2.1.14).


Pssm-ID: 408170 [Multi-domain]  Cd Length: 86  Bit Score: 37.13  E-value: 2.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2216107316 340 VFAKPSNGALIaSWDKV-SDKDLAGYNVYLDGKKINSNLI-SSTNFsiknlennrkykvqvqaVDRSGNAS 408
Cdd:pfam18370  11 VAVPTEEGVFV-SWRLLgTDPDGVAFNVYRDGVKINSAPItDSTNY-----------------LDADGTAS 63
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
33-447 1.54e-25

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 109.71  E-value: 1.54e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316  33 TDAYTKWYIKSYSAEATFKGREEGKSYLYGTEVIADLGAEYSVKYLKYYAQGGIDGGYVYFYDEKFQSVFNQDLKTFGAN 112
Cdd:COG3401    10 DAGIAASAAANTAVNALSKAGGSGKTILVYLAVVLSVTTKESPGTLLVAAGLSSGGGLGTGGRAGTTSGVAAVAVAAAPP 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 113 GQFDVGKKARYVSVGHSTS---RSPNALKVHSFSVFIDDGKVSDVTDLKAKADINKVELTWKNPVEDGFNGVNIYQDDVL 189
Cdd:COG3401    90 TATGLTTLTGSGSVGGATNtglTSSDEVPSPAVGTATTATAVAGGAATAGTYALGAGLYGVDGANASGTTASSVAGAGVV 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 190 --------------MTTLDKSATSYNVGDLKDNTMYRFKVSSLDGGKVETKGVETSVKTLLdpkkIPPSPVSSLVAEP-T 254
Cdd:COG3401   170 vspdtsataavattSLTVTSTTLVDGGGDIEPGTTYYYRVAATDTGGESAPSNEVSVTTPT----TPPSAPTGLTATAdT 245

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 255 DKTVKLIWKKPSDDDLAGFKIL------ENGKKIAEIGlEEEFTVKNLEPLTEYNFGVVAVDKDKNDSSPVN-LSVKTle 327
Cdd:COG3401   246 PGSVTLSWDPVTESDATGYRVYrsnsgdGPFTKVATVT-TTSYTDTGLTNGTTYYYRVTAVDAAGNESAPSNvVSVTT-- 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 328 ekDDVPPHVPSNV-FAKPSNGALIASWDKVSDKDLAGYNVYLDGKKINS-----NLISSTNFSIKNLENNRKYKVQVQAV 401
Cdd:COG3401   323 --DLTPPAAPSGLtATAVGSSSITLSWTASSDADVTGYNVYRSTSGGGTytkiaETVTTTSYTDTGLTPGTTYYYKVTAV 400

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 2216107316 402 DRSGNASELSSPVFGTPDMNTIPLVESKYNLQDVSDGVGNQFWQIW 447
Cdd:COG3401   401 DAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAAS 446
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 243-311 4.42e-07

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 47.61  E-value: 4.42e-07
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2216107316  243 PSPVSSLVAEPTDKT-VKLIWKKPSDDDLAGFKI---------LENGKKIAEIGLEEEFTVKNLEPLTEYNFGVVAVDK 311
Cdd:smart00060   1 PSPPSNLRVTDVTSTsVTLSWEPPPDDGITGYIVgyrveyreeGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNG 79
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 334-417 8.70e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.11  E-value: 8.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 334 PHVPSNVFAKP-SNGALIASWDKVSD--KDLAGYNVYL------DGKKINSNLISSTNFSIKNLENNRKYKVQVQAVDRS 404
Cdd:cd00063     1 PSPPTNLRVTDvTSTSVTLSWTPPEDdgGPITGYVVEYrekgsgDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|...
gi 2216107316 405 GNaSELSSPVFGT 417
Cdd:cd00063    81 GE-SPPSESVTVT 92
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
301-427 4.67e-06

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 49.17  E-value: 4.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 301 EYNFGVVAVDKDKNDSSPVNLSVKTLEEKDDVPPhVPSNVFAKPSNGALIASWDKVSDKDLAGYNVY------LDGKKIN 374
Cdd:COG4733   598 DYEVRVRAINALGVSSAWAASSETTVTGKTAPPP-APTGLTATGGLGGITLSWSFPVDADTLRTEIRysttgdWASATVA 676

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2216107316 375 SNLISSTNFSIKNLENNRKYKVQVQAVDRSGNASELssPVFGTPDMNTIPLVE 427
Cdd:COG4733   677 QALYPGNTYTLAGLKAGQTYYYRARAVDRSGNVSAW--WVSGQASADAAGILD 727
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
196-319 9.15e-06

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 48.40  E-value: 9.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 196 SATSYNVGDLKDNTmYRFKVSSLDGGKVETKGvETSVKTLLDPKKIPPSPVSSLVAEPTDKTVKLIWKKPSDDDLAGFKI 275
Cdd:COG4733   585 SGTSFEVPGIYAGD-YEVRVRAINALGVSSAW-AASSETTVTGKTAPPPAPTGLTATGGLGGITLSWSFPVDADTLRTEI 662

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2216107316 276 -------LENGKKIAEIGLEEEFTVKNLEPLTEYNFGVVAVDKDKNDSSPV 319
Cdd:COG4733   663 rysttgdWASATVAQALYPGNTYTLAGLKAGQTYYYRARAVDRSGNVSAWW 713
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 243-312 3.91e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 42.48  E-value: 3.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 243 PSPVSSLVAEPTDKT-VKLIWKKPSDD--DLAGFKIL------ENGKKIA-EIGLEEEFTVKNLEPLTEYNFGVVAVDKD 312
Cdd:cd00063     1 PSPPTNLRVTDVTSTsVTLSWTPPEDDggPITGYVVEyrekgsGDWKEVEvTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 150-221 5.94e-05

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.45  E-value: 5.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316  150 KVSDVTDlkakadiNKVELTWKNPVEDGFNGVNIY--------QDDVLMTTLDKSATSYNVGDLKDNTMYRFKVSSLDGG 221
Cdd:smart00060   8 RVTDVTS-------TSVTLSWEPPPDDGITGYIVGyrveyreeGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
143-391 1.11e-04

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 44.61  E-value: 1.11e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 143 SVFIDDGKVSDVTDLKAKA-DINKVELTWKNPVEDGFNGVNIYQDDVLMTTLDK-----SATSYNVGDLKDNTMYRFKVS 216
Cdd:COG3401   319 SVTTDLTPPAAPSGLTATAvGSSSITLSWTASSDADVTGYNVYRSTSGGGTYTKiaetvTTTSYTDTGLTPGTTYYYKVT 398

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 217 SLDGGKVETKGVETSVKTLLDPKKIPPSPVSSLVAEPTDKTVKLIWKKPSDDDLAGFKILENGKKIAEIGLEEEFTVKNL 296
Cdd:COG3401   399 AVDAAGNESAPSEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLADGGDTGNAVPFTTTSSTVT 478

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 297 EPLTEYNFGVVAVDKDKNDSSPVNLSVkTLEEKDDVPPHVPSNVFAKPSNGAlIASWDKVSDKDLAGYNVYLDGKKINSN 376
Cdd:COG3401   479 ATTTDTTTANLSVTTGSLVGGSGASSV-TNSVSVIGASAAAAVGGAPDGTPN-VTGASPVTVGASTGDVLITDLVSLTTS 556

                         250
                  ....*....|....*
gi 2216107316 377 LISSTNFSIKNLENN 391
Cdd:COG3401   557 ASSSVSGAGLGSGNL 571
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
333-453 4.49e-04

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 42.45  E-value: 4.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 333 PPHVPSNVFAKPSNGA-LIASWDKVSD-KDLAGYNVYLDGKKINSnLISSTNFSIKNLENNRKYKVQVQAVDRSGNASEL 410
Cdd:COG3979     2 APTAPTGLTASNVTSSsVSLSWDASTDnVGVTGYDVYRGGDQVAT-VTGLTAWTVTGLTPGTEYTFTVGACDAAGNVSAA 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2216107316 411 SSPVFGTPDMNTIPLVESKYNLQDVSDGVGNQFWQIWPFLAWY 453
Cdd:COG3979    81 SGTSTAMFGGSSTTLGSAEGVADTSGNLAASGAFFGVTTPPTP 123
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 333-405 1.46e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.59  E-value: 1.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316  333 PPHVPSNVFAKPSNGALIASWDKVSDKDLAGYNVYL--------DGKKINSNLISSTNFSIKNLENNRKYKVQVQAVDRS 404
Cdd:smart00060   1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGITGYIVGYrveyreegSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                   .
gi 2216107316  405 G 405
Cdd:smart00060  81 G 81
RGI_lyase pfam18370
Rhamnogalacturonan I lyases beta-sheet domain; This is the beta-sheet domain found in ...
 340-408 2.31e-03

Rhamnogalacturonan I lyases beta-sheet domain; This is the beta-sheet domain found in rhamnogalacturonan (RG) lyases, which are responsible for an initial cleavage of the RG type I (RG-I) region of plant cell wall pectin. Polysaccharide lyase family 11 carrying this domain, such as YesW (EC:4.2.2.23) and YesX (EC:4.2.2.24), cleave glycoside bonds between rhamnose and galacturonic acid residues in RG-I through a beta-elimination reaction. Other family members carrying this domain are hemagglutinin A, lysine gingipain (Kgp) and Chitinase C (EC:3.2.1.14).


Pssm-ID: 408170 [Multi-domain]  Cd Length: 86  Bit Score: 37.13  E-value: 2.31e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2216107316 340 VFAKPSNGALIaSWDKV-SDKDLAGYNVYLDGKKINSNLI-SSTNFsiknlennrkykvqvqaVDRSGNAS 408
Cdd:pfam18370  11 VAVPTEEGVFV-SWRLLgTDPDGVAFNVYRDGVKINSAPItDSTNY-----------------LDADGTAS 63
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 150-234 3.39e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 36.71  E-value: 3.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 150 KVSDVTDlkakadiNKVELTWKNPVEDGFNGVN---IYQDD-----VLMTTLDKSATSYNVGDLKDNTMYRFKVSSLDGG 221
Cdd:cd00063     8 RVTDVTS-------TSVTLSWTPPEDDGGPITGyvvEYREKgsgdwKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGG 80

                          90
                  ....*....|...
gi 2216107316 222 KVETKGVETSVKT 234
Cdd:cd00063    81 GESPPSESVTVTT 93
fn3 pfam00041
Fibronectin type III domain;
242-309 4.12e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 36.24  E-value: 4.12e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2216107316 242 PPSPVSslVAEPTDKTVKLIWKKPSD--DDLAGFKI----LENGKKIAEI---GLEEEFTVKNLEPLTEYNFGVVAV 309
Cdd:pfam00041   2 APSNLT--VTDVTSTSLTVSWTPPPDgnGPITGYEVeyrpKNSGEPWNEItvpGTTTSVTLTGLKPGTEYEVRVQAV 76
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
241-318 4.70e-03

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 39.37  E-value: 4.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 241 IPPSPVSSLVA-EPTDKTVKLIWKKPSDD-DLAGFKILENGKKIAEIGLEEEFTVKNLEPLTEYNFGVVAVDKDKNDSSP 318
Cdd:COG3979     1 QAPTAPTGLTAsNVTSSSVSLSWDASTDNvGVTGYDVYRGGDQVATVTGLTAWTVTGLTPGTEYTFTVGACDAAGNVSAA 80
RGL11 cd10318
Rhamnogalacturonan lyase of the polysaccharide lyase family 11; The rhamnogalacturonan lyase ...
 340-453 5.49e-03

Rhamnogalacturonan lyase of the polysaccharide lyase family 11; The rhamnogalacturonan lyase of the polysaccharide lyase family 11 (RGL11) cleaves glycoside bonds in polygalacturonan as well as RG (rhamnogalacturonan) type-I through a beta-elimination reaction. Functionally characterized members of this family, YesW and YesX from Bacillus subtilis, cleave glycoside bonds between rhamnose and galacturonic acid residues in the RG-I region of plant cell wall pectin. YesW and YesX work synergistically, with YesW cleaving the glycoside bond of the RG chain endolytically, and YesX converting the resultant oligosaccharides through an exotype reaction. This domain is sometimes found in architectures with non-catalytic carbohydrate-binding modules (CBMs). There are two types of RG lyases, which both cleave the alpha-1,4 bonds of the RG-I main chain through a beta-elimination reaction, but belong to two structurally unrelated polysaccharide lyase (PL) families, 4 and 11.


Pssm-ID: 199906 [Multi-domain]  Cd Length: 564  Bit Score: 39.17  E-value: 5.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2216107316 340 VFAKPSNGALIaSWDK-VSDKDLAGYNVYLDGKKINSNLIS-STNFSIKNLENNRKYKVQVqAVDRSGNASELSSPVFGT 417
Cdd:cd10318     9 VAVKTGNGVFV-SWRLlGTDPDGIGFNVYRDGVKLNSAPITnSTNFLDAKGTASSKYTVRA-VVNGVEQTESESVEVWAN 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2216107316 418 ---------PDMNTIPLVES-KYNLQDVS----DGVGNqfWQIwpFLAWY 453
Cdd:cd10318    87 pyleiplnkPAGGTTPDGETyTYTANDASvgdlDGDGE--YEI--VLKWD 132
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH