|
Name |
Accession |
Description |
Interval |
E-value |
| valS |
PRK14900 |
valyl-tRNA synthetase; Provisional |
1-1125 |
0e+00 |
|
valyl-tRNA synthetase; Provisional
Pssm-ID: 237855 [Multi-domain] Cd Length: 1052 Bit Score: 1763.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 1 MTDTTELSKAYEPTEVEARRYAFWLERNYFRA-EAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNA 79
Cdd:PRK14900 9 NENRTELAKGYEHREVEARWYPFWQERGYFHGdEHDRTRPPFSIVLPPPNVTGSLHLGHALTATLQDVLIRWKRMSGFNT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 80 LWLPGTDHAGIATQMVVERELKQTEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAV 159
Cdd:PRK14900 89 LWLPGTDHAGIATQMIVEKELKKTEKKSRHDLGREAFLERVWAWKEQYGSRIGEQHKALGASLDWQRERFTMDEGLSRAV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 160 REVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVEHQE-KNGSIWHIRYPVKDTDRTLTVATTRPETMLGDTAVAVHPE 238
Cdd:PRK14900 169 REVFVRLHEEGLIYREKKLINWCPDCRTALSDLEVEHEEaHQGELWSFAYPLADGSGEIVVATTRPETMLGDTAVAVHPL 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 239 DERYQDLIGKHVVLPLSGREIPIIADAELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTKETGKYAGL 318
Cdd:PRK14900 249 DPRYMALHGKKVRHPITGRTFPIVADAILVDPKFGTGAVKVTPAHDFNDFEVGKRHGLEMITVIGPDGRMTAEAGPLAGL 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 319 DRFEARKQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQGRTKFVPESWTNTYFH 398
Cdd:PRK14900 329 DRFEARKEVKRLLAEQGLDRGAKPHVLPLGRCQRSATILEPLLSDQWYVRIEPLARPAIEAVEQGRTRFIPEQWTNTYMA 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 399 WMRNIHDWCVSRQLWWGHQIPAYYCTAcsprlgddtdlpldsatvkvggvdfarAEPIVAREQPSSCPKCGGATFIQDPD 478
Cdd:PRK14900 409 WMRNIHDWCISRQLWWGHQIPAWYCPD---------------------------GHVTVARETPEACSTCGKAELRQDED 461
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 479 VLDTWFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSK 558
Cdd:PRK14900 462 VLDTWFSSGLWPFSTMGWPEQTDTLRTFYPTSVMETGHDIIFFWVARMMMMGLHFMGEVPFRTVYLHPMVRDEKGQKMSK 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 559 TKKNVIDPLDVIlgapadkleptlrnkfpqgmPAFGADALRFTLASLTQQGRDIKLSMDRMAGYKAFCNKLWNASRFALM 638
Cdd:PRK14900 542 TKGNVIDPLVIT--------------------EQYGADALRFTLAALTAQGRDIKLAKERIEGYRAFANKLWNASRFALM 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 639 NMGEFTLDERPLKERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLYGTDEQAKD 718
Cdd:PRK14900 602 NLSGYQERGEDPARLARTPADRWILARLQRAVNETVEALEAFRFNDAANAVYAFVWHELCDWYIELAKEALASEDPEARR 681
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 719 SARAVLVYSLDRILRLLHPFMPFITEEIWQKLPMSRSV----DSIMIASYPEPDAdlVDEAAEAEMAPVIASIEGLRTIR 794
Cdd:PRK14900 682 SVQAVLVHCLQTSYRLLHPFMPFITEELWHVLRAQVGAsawaDSVLAAEYPRKGE--ADEAAEAAFRPVLGIIDAVRNIR 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 795 GESNLSPATKV----KAVVQSPDARTRELLER-WRAYLMPLAGLSDVEI--GAPGTKPPQAAAFVGTNLEIYVPLAGLID 867
Cdd:PRK14900 760 GEMGIPWKVKLgaqaPVEIAVADPALRDLLQAgELARVHRVAGVEGSRLvvAAATAPAPQSAVGVGPGFEVRVPLAGVID 839
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 868 LDAERDRLRKEIARTEQEAAGVLRKLENPNFVAKAPPDVVEKDRARVEELKERKAKLQDHLQRIapepampaappsesrt 947
Cdd:PRK14900 840 LAAETARVDKEIGKVDQDLAVLERKLQNPSFVQNAPPAVVEKDRARAEELREKRGKLEAHRAML---------------- 903
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 948 ptesvepteadivteadvatepitppesaarletpppaeGGAEYETLAESTEEEEEAAAPAEVKAAPDAEAEGNVDLAEE 1027
Cdd:PRK14900 904 ---------------------------------------SGSEANSARRDTMEIQNEQKPTQDGPAAEAQPAQENTVVES 944
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 1028 LKDELEAVGGVPEAADPQVQDALEKLRAGT-KEGLSPADHHDLGVAYMSMGLVDDAmrefntARAGGDAREAPA---AAE 1103
Cdd:PRK14900 945 AEKAVAAVSEAAQQAATAVASGIEKVAEAVrKTVRRSVKKAAATRAAMKKKVAKKA------PAKKAAAKKAAAkkaAAK 1018
|
1130 1140
....*....|....*....|..
gi 2318732569 1104 QTVASTAKAVVKATLAAVKKAS 1125
Cdd:PRK14900 1019 KKVAKKAPAKKVARKPAAKKAA 1040
|
|
| ValS |
COG0525 |
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase ... |
5-931 |
0e+00 |
|
Valyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Valyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440291 [Multi-domain] Cd Length: 877 Bit Score: 1679.44 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 5 TELSKAYEPTEVEARRYAFWLERNYFRAEAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPG 84
Cdd:COG0525 1 MELPKTYDPKEVEAKWYQYWEENGYFKADPDSDKEPFTIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWQPG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 85 TDHAGIATQMVVERELKQtEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFV 164
Cdd:COG0525 81 TDHAGIATQAVVERQLAE-EGKSRHDLGREKFLERVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREVFV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 165 RLYEEGLMYRAQKLINWCPSCHTALSDLEVEHQEKNGSIWHIRYPVKDTDRTLTVATTRPETMLGDTAVAVHPEDERYQD 244
Cdd:COG0525 160 RLYEKGLIYRGKRLVNWDPKLKTALSDLEVEHEEVKGHLWHIRYPLADGSGYIVVATTRPETMLGDTAVAVHPEDERYKH 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 245 LIGKHVVLPLSGREIPIIADaELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTKETGKYAGLDRFEAR 324
Cdd:COG0525 240 LIGKTVILPLVGREIPIIAD-EYVDPEFGTGAVKITPAHDPNDFEVGKRHNLPMINILDEDGTINENAGKYRGLDRFEAR 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 325 KQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQGRTKFVPESWTNTYFHWMRNIH 404
Cdd:COG0525 319 KAIVADLEELGLLVKVEPHKHSVGHSDRSGTVIEPYLSDQWFVKMKPLAKPAIEAVEDGEIKFVPERWEKTYFHWMENIR 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 405 DWCVSRQLWWGHQIPAYYCtacsprlgDDtdlpldsatvkvggvdfarAEPIVAREQPSSCPKCGGATFIQDPDVLDTWF 484
Cdd:COG0525 399 DWCISRQLWWGHRIPAWYC--------PD-------------------GEVYVARTEPEACAKAGSVNLTQDEDVLDTWF 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 485 SSALWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKNVI 564
Cdd:COG0525 452 SSALWPFSTLGWPEKTEDLKYFYPTSVLVTGFDIIFFWVARMIMMGLHFTGEVPFKDVYIHGLVRDEQGRKMSKSKGNVI 531
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 565 DPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASLTQQGRDIKLSMDRMAGYKAFCNKLWNASRFALMNMGEFT 644
Cdd:COG0525 532 DPLDLI-----DK---------------YGADALRFTLAALASPGRDIKFDEERVEGYRNFANKLWNASRFVLMNLEGFD 591
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 645 LDERPLKErPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLYGTDEQAKDSARAVL 724
Cdd:COG0525 592 PGLDPDPE-ELSLADRWILSRLNKTIAEVTEALEKYRFDEAAQALYDFVWNEFCDWYLELAKPRLYGGDEAAKRETRATL 670
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 725 VYSLDRILRLLHPFMPFITEEIWQKLPMSRSVDSIMIASYPEPDADLVDEAAEAEMAPVIASIEGLRTIRGESNLSPATK 804
Cdd:COG0525 671 VYVLEQILRLLHPFMPFITEEIWQKLPPRKEGESIMLAPWPEADEELIDEEAEAEFEWLKEVISAIRNIRAEMNIPPSKK 750
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 805 VKAVVQSPDARTRELLERWRAYLMPLAGLSDVEIGApGTKPPQAAAFVGTNLEIYVPLAGLIDLDAERDRLRKEIARTEQ 884
Cdd:COG0525 751 LPLLLKGADEADRARLEENAAYIKRLARLEEITILV-DEKPEGAASAVVGGAEVFLPLEGLIDVEAERARLEKELAKLEK 829
|
890 900 910 920
....*....|....*....|....*....|....*....|....*..
gi 2318732569 885 EAAGVLRKLENPNFVAKAPPDVVEKDRARVEELKERKAKLQDHLQRI 931
Cdd:COG0525 830 EIARVEKKLSNEGFVAKAPAEVVEKEREKLAEAEAKLEKLEEQLARL 876
|
|
| valS |
PRK05729 |
valyl-tRNA synthetase; Reviewed |
3-931 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 235582 [Multi-domain] Cd Length: 874 Bit Score: 1585.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 3 DTTELSKAYEPTEVEARRYAFWLERNYFRAEAPSDKPpFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWL 82
Cdd:PRK05729 1 MMMELPKTYDPKEVEAKWYQKWEEKGYFKPDDNSKKP-FSIVIPPPNVTGSLHMGHALNNTLQDILIRYKRMQGYNTLWL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 83 PGTDHAGIATQMVVERELKQtEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREV 162
Cdd:PRK05729 80 PGTDHAGIATQMVVERQLAA-EGKSRHDLGREKFLEKVWEWKEESGGTITNQLRRLGASCDWSRERFTMDEGLSKAVREV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 163 FVRLYEEGLMYRAQKLINWCPSCHTALSDLEVEHQEKNGSIWHIRYPVKDTDRTLTVATTRPETMLGDTAVAVHPEDERY 242
Cdd:PRK05729 159 FVRLYEKGLIYRGKRLVNWDPKLQTALSDLEVEYKEVKGKLWHIRYPLADGSDYLVVATTRPETMLGDTAVAVNPEDERY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 243 QDLIGKHVVLPLSGREIPIIADaELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTKETGKYAGLDRFE 322
Cdd:PRK05729 239 KHLIGKTVILPLVGREIPIIAD-EYVDPEFGTGAVKITPAHDPNDFEVGKRHNLPMINIMDEDGTINENPGEYQGLDRFE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 323 ARKQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQGRTKFVPESWTNTYFHWMRN 402
Cdd:PRK05729 318 ARKAIVADLEELGLLVKIEPHTHSVGHSDRSGVVIEPYLSDQWFVKMKPLAKPALEAVENGEIKFVPERWEKTYFHWMEN 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 403 IHDWCVSRQLWWGHQIPAYYCTACsprlgddtdlpldsatvkvggvdfaraEPIVAREQPSSCPKCggaTFIQDPDVLDT 482
Cdd:PRK05729 398 IQDWCISRQLWWGHRIPAWYDEDG---------------------------EVYVGREEPEAREKA---LLTQDEDVLDT 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 483 WFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKN 562
Cdd:PRK05729 448 WFSSALWPFSTLGWPEKTEDLKRFYPTSVLVTGFDIIFFWVARMIMMGLHFTGQVPFKDVYIHGLVRDEQGRKMSKSKGN 527
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 563 VIDPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASLTQQGRDIKLSMDRMAGYKAFCNKLWNASRFALMNMGE 642
Cdd:PRK05729 528 VIDPLDLI-----DK---------------YGADALRFTLAALASPGRDIRFDEERVEGYRNFANKLWNASRFVLMNLEG 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 643 FTLDERPLKErPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLYgtdEQAKDSARA 722
Cdd:PRK05729 588 ADVGELPDPE-ELSLADRWILSRLNRTVAEVTEALDKYRFDEAARALYEFIWNEFCDWYLELAKPVLQ---EAAKRATRA 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 723 VLVYSLDRILRLLHPFMPFITEEIWQKLPMSRSVDSIMIASYPEPDADLvDEAAEAEMAPVIASIEGLRTIRGESNLSPA 802
Cdd:PRK05729 664 TLAYVLEQILRLLHPFMPFITEELWQKLAPLGIEESIMLAPWPEADEAI-DEAAEAEFEWLKELITAIRNIRAEMNIPPS 742
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 803 TKVKAVVQSPDARTRELLERWRAYLMPLAGLSDVEIGAPGTKPPQ-AAAFVGTNLEIYVPLAGLIDLDAERDRLRKEIAR 881
Cdd:PRK05729 743 KKLPLLLKGADAEDRARLEANEAYIKRLARLESLEILADDEEAPEgAASAVVGGAELFLPLEGLIDVEAELARLEKELAK 822
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|
gi 2318732569 882 TEQEAAGVLRKLENPNFVAKAPPDVVEKDRARVEELKERKAKLQDHLQRI 931
Cdd:PRK05729 823 LEKEIERVEKKLSNEGFVAKAPEEVVEKEREKLAEYEEKLAKLKERLARL 872
|
|
| valS |
TIGR00422 |
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase ... |
9-911 |
0e+00 |
|
valyl-tRNA synthetase; The valyl-tRNA synthetase (ValS) is a class I amino acyl-tRNA ligase and is particularly closely related to the isoleucyl tRNA synthetase. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273070 [Multi-domain] Cd Length: 861 Bit Score: 1204.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 9 KAYEPTEVEARRYAFWLERNYFRAEAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHA 88
Cdd:TIGR00422 3 KDYDPHEVEKKWYKKWEKSGFFKPDGNSNKPPFCIDIPPPNVTGSLHIGHALNWSIQDIIARYKRMKGYNVLWLPGTDHA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 89 GIATQMVVERELKQtEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYE 168
Cdd:TIGR00422 83 GIATQVKVEKKLGA-EGKTKHDLGREEFREKIWEWKEESGGTIKNQIKRLGASLDWSRERFTMDEGLSKAVKEAFVRLYE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 169 EGLMYRAQKLINWCPSCHTALSDLEVEHQEKNGSIWHIRYPVKDTDRT-LTVATTRPETMLGDTAVAVHPEDERYQDLIG 247
Cdd:TIGR00422 162 KGLIYRGEYLVNWDPKLNTAISDIEVEYKEVKGKLYYIRYPLANGSKDyLVVATTRPETMFGDTAVAVHPEDERYKHLIG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 248 KHVVLPLSGREIPIIADaELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTKETGKYAGLDRFEARKQV 327
Cdd:TIGR00422 242 KKVILPLTGRKIPIIAD-EYVDMEFGTGAVKVTPAHDFNDYEWGKRHNLEFINILDEDGLLNENAGKYQGLTRFEARKKI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 328 LADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQGRTKFVPESWTNTYFHWMRNIHDWC 407
Cdd:TIGR00422 321 VEDLKEEGLLVKIEPHTHNVGTCWRSGTVVEPLLSKQWFVKVEKLADKALEAAEEGEIKFVPKRMEKRYLNWLRNIKDWC 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 408 VSRQLWWGHQIPAYYCTACsprlgddtdlpldsatvkvGGVDFARAEPIVAREQPSSCPKcggaTFIQDPDVLDTWFSSA 487
Cdd:TIGR00422 401 ISRQLIWGHRIPVWYCKEC-------------------GEVYVAKEEPLPDDKTNTGPSV----ELEQDTDVLDTWFSSS 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 488 LWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKNVIDPL 567
Cdd:TIGR00422 458 LWPFSTLGWPDETKDLKKFYPTDLLVTGYDIIFFWVARMIFRSLALTGQVPFKEVYIHGLVRDEQGRKMSKSLGNVIDPL 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 568 DVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASLTQQGRDIKLSMDRMAGYKAFCNKLWNASRFALMNMGEFTLDE 647
Cdd:TIGR00422 538 DVI-----EK---------------YGADALRFTLASLVTPGDDINFDWKRVESARNFLNKLWNASRFVLMNLSDDLELS 597
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 648 RPlkERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLYGTDEQAKDSARAVLVYS 727
Cdd:TIGR00422 598 GG--EEKLSLADRWILSKLNRTIKEVRKALDKYRFAEAAKALYEFIWNDFCDWYIELVKYRLYNGNEAEKKAARDTLYYV 675
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 728 LDRILRLLHPFMPFITEEIWQKLPmsRSVDSIMIASYPEPDADLVDEAAEAEMAPVIASIEGLRTIRGESNLSPATKVKA 807
Cdd:TIGR00422 676 LDKALRLLHPFMPFITEEIWQHFK--EGADSIMLQSYPVVDAEFVDEEAEKAFELLKEIIVSIRNLKAESNIPPNAPLKV 753
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 808 VVQSPDARTRELLERWRAYLMPLAGLSDVEIGAPGTKPPQAAAFVGTNLEIYVPLAGLIDLDAERDRLRKEIARTEQEAA 887
Cdd:TIGR00422 754 LLIYTEAETAERLKLNAVDIKGAINFSEVEVVIEKPEVTEAVVELVPGFEIIIPVKGLINKAKELARLQKQLDKEKKEVI 833
|
890 900
....*....|....*....|....
gi 2318732569 888 GVLRKLENPNFVAKAPPDVVEKDR 911
Cdd:TIGR00422 834 RIEGKLENEGFVKKAPKEVIEKEK 857
|
|
| PTZ00419 |
PTZ00419 |
valyl-tRNA synthetase-like protein; Provisional |
3-926 |
0e+00 |
|
valyl-tRNA synthetase-like protein; Provisional
Pssm-ID: 240411 [Multi-domain] Cd Length: 995 Bit Score: 1176.33 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 3 DTTELSKAYEPTEVEARRYAFWLERNYFR----AEAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFN 78
Cdd:PTZ00419 20 NISSMAASYDPKEVESGWYEWWEKSGFFKpaedAKSLNSGKKFVIVLPPPNVTGYLHIGHALTGAIQDSLIRYHRMKGDE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 79 ALWLPGTDHAGIATQMVVERELKQTEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAA 158
Cdd:PTZ00419 100 TLWVPGTDHAGIATQVVVEKKLMKEENKTRHDLGREEFLKKVWEWKDKHGNNICNQLRRLGSSLDWSREVFTMDEQRSKA 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 159 VREVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVEHQE--KN--------------GSIWHIRYPVKDT-DRTLTVAT 221
Cdd:PTZ00419 180 VKEAFVRLYEDGLIYRDTRLVNWCCYLKTAISDIEVEFEEieKPtkitipgydkkvevGVLWHFAYPLEDSgQEEIVVAT 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 222 TRPETMLGDTAVAVHPEDERYQDLIGKHVVLP-LSGREIPIIADAELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLS 300
Cdd:PTZ00419 260 TRIETMLGDVAVAVHPKDERYKKLHGKELIHPfIPDRKIPIIADDELVDMEFGTGAVKITPAHDPNDYEIAKRHNLPFIN 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 301 ILDESARMTKETGKYAGLDRFEARKQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAV 380
Cdd:PTZ00419 340 IFTLDGKINENGGEFAGMHRFDCRRKIEEELKEMGLLRDKVPNPMRLPRCSRSGDIVEPMLIPQWYVNCKDMAKRAVEAV 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 381 EQGRTKFVPESWTNTYFHWMRNIHDWCVSRQLWWGHQIPAYYCTACSPRLGDDTDLPLdsatvkVGGVDFARAEPIVARE 460
Cdd:PTZ00419 420 RNGELKIIPSSHENVWYHWLENIQDWCISRQLWWGHRIPAYRVISKGPETDPSDEEPW------VVARSEEEALEKAKKK 493
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 461 QPSSCPKCggaTFIQDPDVLDTWFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFR 540
Cdd:PTZ00419 494 FGLSEEDF---ELEQDEDVLDTWFSSGLFPFSTLGWPDQTDDLQRFFPTSLLETGSDILFFWVARMVMMSLHLTDKLPFK 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 541 TVYLHAMVRDEKGEKMSKTKKNVIDPLDVILGAPADKLEPTLRN-----------------KFPQGMPAFGADALRFTLA 603
Cdd:PTZ00419 571 TVFLHAMVRDSQGEKMSKSKGNVIDPLEVIEGISLQDLNQKLYEgnlpekeikraielqkkEFPNGIPECGTDALRFGLL 650
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 604 SLTQQGRDIKLSMDRMAGYKAFCNKLWNASRFALMNMGEF-----TLDERPLKERPLTLADRWILSRLQRATTEARASLE 678
Cdd:PTZ00419 651 AYTQQGRNINLDINRVVGYRHFCNKLWNAVKFALMKLLKDfnlpnSTLFKPNNVESLPWEDKWILHRLNVAIKEVTEGFK 730
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 679 TYGFAEAASTLYQFLWAEFCDWYIELAKGSL-YGTDEQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKLP-MSRSV 756
Cdd:PTZ00419 731 EYDFSEATQATYNFWLYELCDVYLELIKPRLsKQSDGERKQHAQDVLHTVLDIGLRLLHPMMPFITEELYQRLPnYLRKS 810
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 757 DSIMIASYPEPDADLVDEAAEAEMAPVIASIEGLRTIRGESNLSPATKVKAVVQSPDARTRELLERWRAYLMPLAGLSDV 836
Cdd:PTZ00419 811 ESISIAKYPQPNPGWNNEALDEEMKIIMSIVKSIRSLIATLGIPNKTKPDCYVTAKDAELIELIESAENLISTLAKIGSV 890
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 837 EIGAPGTK----PPQA-AAFVGTNLEIYVPLAGLIDLDAERDRLRKEIARTEQEAAGVLRKLENPNFVAKAPPDVVEKDR 911
Cdd:PTZ00419 891 SVIPPIEEeaevPKGCgFDVVDNKVIIYLNLDEFIDLKKELAKLEKKLAKLQKSLESYLKKISIPNYEDKVPEDVRKLND 970
|
970
....*....|....*
gi 2318732569 912 ARVEELKERKAKLQD 926
Cdd:PTZ00419 971 EKIDELNEEIKQLEQ 985
|
|
| PLN02381 |
PLN02381 |
valyl-tRNA synthetase |
4-919 |
0e+00 |
|
valyl-tRNA synthetase
Pssm-ID: 215214 [Multi-domain] Cd Length: 1066 Bit Score: 888.09 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 4 TTELSKAYEPTEVEARRYAFWLERNYFRAEAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLP 83
Cdd:PLN02381 93 SSQMAKQYSPSAVEKSWYAWWEKSGYFGADAKSSKPPFVIVLPPPNVTGALHIGHALTAAIEDTIIRWKRMSGYNALWVP 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 84 GTDHAGIATQMVVERELKQTEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVF 163
Cdd:PLN02381 173 GVDHAGIATQVVVEKKLMRERHLTRHDIGREEFVSEVWKWKDEYGGTILNQLRRLGASLDWSRECFTMDEQRSKAVTEAF 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 164 VRLYEEGLMYRAQKLINWCPSCHTALSDLEVEH---QEKN-------------GSIWHIRYPVKDTDRTLTVATTRPETM 227
Cdd:PLN02381 253 VRLYKEGLIYRDIRLVNWDCTLRTAISDVEVDYidiKERTllkvpgydkpvefGVLTSFAYPLEGGLGEIVVATTRIETM 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 228 LGDTAVAVHPEDERYQDLIGKHVVLPLSGREIPIIADAELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESAR 307
Cdd:PLN02381 333 LGDTAIAIHPDDERYKHLHGKFAVHPFNGRKLPIICDAILVDPNFGTGAVKITPAHDPNDFEVGKRHNLEFINIFTDDGK 412
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 308 MTKETG-KYAGLDRFEARKQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQGRTK 386
Cdd:PLN02381 413 INSNGGsEFAGMPRFAAREAVIEALQKKGLYRGAKNNEMRLGLCSRTNDVVEPMIKPQWFVNCSSMAKQALDAAIDGENK 492
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 387 ---FVPESWTNTYFHWMRNIHDWCVSRQLWWGHQIPAYYCTacsprLGDDTDLPLDSATvkvGGVDFARAEPiVAREQPS 463
Cdd:PLN02381 493 kleFIPKQYLAEWKRWLENIRDWCISRQLWWGHRIPAWYVT-----LEDDQLKELGSYN---DHWVVARNES-DALLEAS 563
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 464 ScpKCGGATF--IQDPDVLDTWFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRT 541
Cdd:PLN02381 564 Q--KFPGKKFelSQDPDVLDTWFSSGLFPLSVLGWPDDTDDLKAFYPTSVLETGHDILFFWVARMVMMGMQLGGDVPFRK 641
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 542 VYLHAMVRDEKGEKMSKTKKNVIDPLDVILGAPADKLEPTL-----------------RNKFPQGMPAFGADALRFTLAS 604
Cdd:PLN02381 642 VYLHPMIRDAHGRKMSKSLGNVIDPLEVINGISLEGLHKRLeegnldpkelvvakegqKKDFPNGIAECGTDALRFALVS 721
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 605 LTQQGRDIKLSMDRMAGYKAFCNKLWNASRFALMNMGEFTLDERPLKERPLTLADRWILSRLQRATTEARASLETYGFAE 684
Cdd:PLN02381 722 YTAQSDKINLDILRVVGYRQWCNKLWNAVRFAMSKLGDDYTPPATLSVETMPFSCKWILSVLNKAISKTVSSLDAYEFSD 801
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 685 AASTLYQFLWAEFCDWYIELAKGSLYGTD---EQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKLPMSRSV---DS 758
Cdd:PLN02381 802 AASTVYSWWQYQFCDVFIEAIKPYFAGDNpefASERAAAQDTLWICLDTGLRLLHPFMPFVTEELWQRLPQPKDHtrkDS 881
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 759 IMIASYPEPDADLVDEAAEAEMAPVIASIEGLRTIRGEsnLSPATKVKAVVQSPDARTRELLERWRAY---LMPLAGLSD 835
Cdd:PLN02381 882 IMISEYPSAVEAWTNEKVEYEMDLVLSTVKCLRSLRAE--VLEKQKNERLPAFALCRNQEIAAIIKSHqleILTLANLSS 959
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 836 VEIGAPGT-KPPQAAAF--VGTNLEIYVPLAGLIDLDAERDRLRKEIARTEQEAAGVLRKLENPNFVAKAPPDVVEKDRA 912
Cdd:PLN02381 960 LKVLLSENdAPPAGCAFenVNENLKVYLQAQGAVNAEAELEKLRNKMDEIQKQQEKLEKKMNASGYKEKVPANIQEEDAR 1039
|
....*..
gi 2318732569 913 RVEELKE 919
Cdd:PLN02381 1040 KLTKLLQ 1046
|
|
| PLN02943 |
PLN02943 |
aminoacyl-tRNA ligase |
6-920 |
0e+00 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215509 [Multi-domain] Cd Length: 958 Bit Score: 851.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 6 ELSKAYEPTEvEARRYAFWLERNYFRAEAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGT 85
Cdd:PLN02943 56 ETAKSFDFTS-EERIYNWWESQGYFKPNFDRGGDPFVIPMPPPNVTGSLHMGHAMFVTLEDIMVRYNRMKGRPTLWIPGT 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 86 DHAGIATQMVVERELKqTEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVR 165
Cdd:PLN02943 135 DHAGIATQLVVEKMLA-SEGIKRTDLGRDEFTKRVWEWKEKYGGTITNQIKRLGASCDWSRERFTLDEQLSRAVVEAFVR 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 166 LYEEGLMYRAQKLINWCPSCHTALSDLEVEHQEKNGSIWHIRYPVK-DTDRTLTVATTRPETMLGDTAVAVHPEDERYQD 244
Cdd:PLN02943 214 LHEKGLIYQGSYMVNWSPNLQTAVSDLEVEYSEEPGTLYYIKYRVAgGSEDFLTIATTRPETLFGDVAIAVNPEDDRYSK 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 245 LIGKHVVLPLS-GREIPIIADaELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTketgKYAGLDRFEA 323
Cdd:PLN02943 294 YIGKMAIVPMTyGRHVPIIAD-RYVDKDFGTGVLKISPGHDHNDYLLARKLGLPILNVMNKDGTLN----EVAGLYWFEA 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 324 RKQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQGRTKFVPESWTNTYFHWMRNI 403
Cdd:PLN02943 369 REKLWSDLEETGLAVKKEPHTLRVPRSQRGGEVIEPLVSKQWFVTMEPLAEKALKAVENGELTIIPERFEKIYNHWLSNI 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 404 HDWCVSRQLWWGHQIPAYYCtacsprLGDDTDlpldsatvkvggvdfarAEPIVAREQPSSCPKC-----GGATFIQDPD 478
Cdd:PLN02943 449 KDWCISRQLWWGHRIPVWYI------VGKDCE-----------------EDYIVARSAEEALEKArekygKDVEIYQDPD 505
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 479 VLDTWFSSALWPFSTLGWPR-NTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMS 557
Cdd:PLN02943 506 VLDTWFSSALWPFSTLGWPDvSAEDFKKFYPTTVLETGHDILFFWVARMVMMGIEFTGTVPFSYVYLHGLIRDSQGRKMS 585
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 558 KTKKNVIDPLDVIlgapadkleptlrnkfpqgmPAFGADALRFTLAsLTQQGRDIKLSMDRMAGYKAFCNKLWNASRFAL 637
Cdd:PLN02943 586 KTLGNVIDPLDTI--------------------KEFGTDALRFTLA-LGTAGQDLNLSTERLTSNKAFTNKLWNAGKFVL 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 638 MNMG--------EFTLDERPLKERP---LTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAK 706
Cdd:PLN02943 645 QNLPsqsdtsawEHILACKFDKEESllsLPLPECWVVSKLHELIDSVTTSYDKYFFGDVGREIYDFFWSDFADWYIEASK 724
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 707 GSLYGT-DEQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKLPMSRsvDSIMIASYPEPDADLvDEAAEAEMAPVIA 785
Cdd:PLN02943 725 TRLYHSgDNSALSRAQAVLLYVFENILKLLHPFMPFVTEELWQALPYRK--EALIVSPWPQTSLPK-DLKSIKRFENLQS 801
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 786 SIEGLRTIRGESNLSPATKVKAVVQSpDARTRELLERWRAYLMPLAGLS----DVEIGAPGTKPPQAAAFVGTNLEIYVP 861
Cdd:PLN02943 802 LTRAIRNARAEYSVEPAKRISASIVA-SAEVIEYISKEKEVLALLSRLDlqnvHFTDSPPGDANQSVHLVASEGLEAYLP 880
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*....
gi 2318732569 862 LAGLIDLDAERDRLRKEIARTEQEAAGVLRKLENPNFVAKAPPDVVEKDRARVEELKER 920
Cdd:PLN02943 881 LADMVDISAEVERLSKRLSKMQTEYDALAARLSSPKFVEKAPEDVVRGVREKAAEAEEK 939
|
|
| tRNA-synt_1 |
pfam00133 |
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too ... |
20-615 |
0e+00 |
|
tRNA synthetases class I (I, L, M and V); Other tRNA synthetase sub-families are too dissimilar to be included.
Pssm-ID: 459685 [Multi-domain] Cd Length: 602 Bit Score: 738.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 20 RYAFWLERNYFRA--EAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVE 97
Cdd:pfam00133 2 IYEFWDEQGYFKPelEKRKGKPSFTIHDGPPNATGSLHIGHALAKTLKDIVIRYKRMKGYYVLWVPGWDHHGLPTEQVVE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 98 RELKQTEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLMYRAQK 177
Cdd:pfam00133 82 KKLGIKEKKTRHKYGREEFREKCREWKMEYADEIRKQFRRLGRSIDWDREYFTMDPELEAAVWEVFVRLHDKGLIYRGKK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 178 LINWCPSCHTALSDLEVEHQEKNGSIWHIRYPVKDTDRT-LTVATTRPETMLGDTAVAVHPE------------------ 238
Cdd:pfam00133 162 LVNWSPALNTALSNLEVEYKDVKGPSIHVAFPLADDEGAsLVIWTTTPWTLPGNTAVAVNPEfdyvitgegyilaeallk 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 239 -------------DERYQDLIGKHVVLPLSGREIPIIADaELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDES 305
Cdd:pfam00133 242 slykkgtdkkileDFRGKELEGKEAIHPFVNREIPIITD-DYVDMEFGTGAVHIAPAHGENDYEVGQRHNLEVINPVDDD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 306 ARMTKETGKYAGLDRFEARKQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQgrT 385
Cdd:pfam00133 321 GTFTEEAPDFQGVYRFDARKKIVELLTEKGLLLKIEPFTHSYPFCWRSGTPIIPRATPQWFVRMDELADQALEAVEK--V 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 386 KFVPESWTNTYFHWMRNIHDWCVSRQLWWGHQIPAYYctacsprlgDDtdlplDSATVKVGGVDFARAEPIVARE----- 460
Cdd:pfam00133 399 QFVPKSGEKRYFNWLANIQDWCISRQRWWGHPIPAWV---------SK-----DTEEVVCRGELFELVAGRFEEEgsikw 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 461 ---QPSSCPKCGGATFIQDPDVLDTWFSSALWPFSTLGWP-RNTPELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMGD 536
Cdd:pfam00133 465 lhrEAKDKLGYGKGTLEQDEDVLDTWFSSGSWPFSTLGWPfVNTEEFKKFFPADMLLEGSDQTRGWFYRMIMLSTALTGS 544
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2318732569 537 VPFRTVYLHAMVRDEKGEKMSKTKKNVIDPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASlTQQGRDIKLS 615
Cdd:pfam00133 545 VPFKNVLVHGLVRDEQGRKMSKSLGNVIDPLDVI-----DK---------------YGADALRLWLAN-SDYGRDINLS 602
|
|
| valS |
PRK13208 |
valyl-tRNA synthetase; Reviewed |
5-842 |
0e+00 |
|
valyl-tRNA synthetase; Reviewed
Pssm-ID: 237306 [Multi-domain] Cd Length: 800 Bit Score: 657.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 5 TELSKAYEPTEVEARRYAFWLERNYFRAEAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPG 84
Cdd:PRK13208 4 PELPKKYDPEELEEKWQKIWEEEGTYKFDPDERKPVYSIDTPPPTVSGSLHIGHVFSYTHTDFIARYQRMRGYNVFFPQG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 85 TDHAGIATQMVVERELkqteGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFV 164
Cdd:PRK13208 84 WDDNGLPTERKVEKYY----GIRKDDISREEFIELCRELTDEDEKKFRELWRRLGLSVDWSLEYQTISPEYRRISQKSFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 165 RLYEEGLMYRAQKLINWCPSCHTALSDLEVEHQEKNGSIWHIRYPVKDtDRTLTVATTRPETMLGDTAVAVHPEDERYQD 244
Cdd:PRK13208 160 DLYKKGLIYRAEAPVLWCPRCETAIAQAEVEYREREGKLNYIKFPVED-GEEIEIATTRPELLPACVAVVVHPDDERYKH 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 245 LIGKHVVLPLSGREIPIIADaELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTKETGKYAGLDRFEAR 324
Cdd:PRK13208 239 LVGKTAIVPLFGVEVPILAD-PLVDPDFGTGAVMICTFGDKTDVTWWRELNLPTRIIIDEDGRMTEAAGKLAGLTIEEAR 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 325 KQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLaKPAIeaVEQGRT-KFVPESWTNTYFHWMRNI 403
Cdd:PRK13208 318 KKIVEDLKSGGLLGKQEPIKHNVKFCERCDTPLEILVTRQWFIKVLDL-KEEL--LERGKEiNWYPEHMRVRLENWIEGL 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 404 H-DWCVSRQLWWGHQIPAYYCTAC-SPRLGDDTDLPldsatvkvggVDFARAEPIVareqpSSCPKCGGATFIQDPDVLD 481
Cdd:PRK13208 395 NwDWCISRQRYFGTPIPVWYCKDCgHPILPDEEDLP----------VDPTKDEPPG-----YKCPQCGSPGFEGETDVMD 459
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 482 TWFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFW----VARMMmmgLHFmGDVPFRTVYLHAMVRDEKGEKMS 557
Cdd:PRK13208 460 TWATSSITPLIVTGWERDEDLFEKVFPMDLRPQGHDIIRTWlfytILRAY---LLT-GKLPWKNIMISGMVLDPDGKKMS 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 558 KTKKNVIDPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASlTQQGRDIKLSMDRMAGYKAFCNKLWNASRFAL 637
Cdd:PRK13208 536 KSKGNVVTPEELL-----EK---------------YGADAVRYWAAS-ARLGSDTPFDEKQVKIGRRLLTKLWNASRFVL 594
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 638 MnmgeFTLDERPLKERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLYGTD-EQA 716
Cdd:PRK13208 595 H----FSADPEPDKAEVLEPLDRWILAKLAKVVEKATEALENYDFAKALEEIESFFWHVFCDDYLELVKSRAYGEDeEEE 670
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 717 KDSARAVLVYSLDRILRLLHPFMPFITEEIWQKLPMSrsvdSIMIASYPEPDADLVDEAAEAEMAPVIASIEGLRTIRGE 796
Cdd:PRK13208 671 QKSARYTLYTVLDTLLRLLAPFLPFITEEVWSWLYGG----SVHRASWPEPDEELIDEEDEELGELAKEILSAVRKYKSE 746
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 2318732569 797 SNLSPATKVKAVVQSPDArTRELLERWRAYLMPLAGLSDVEIGAPG 842
Cdd:PRK13208 747 AGLSLNAPLKKVEVYGPA-DLELLEAAEEDLKAAGNIEELELVEGD 791
|
|
| ValRS_core |
cd00817 |
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) ... |
39-614 |
0e+00 |
|
catalytic core domain of valyl-tRNA synthetases; Valine amino-acyl tRNA synthetase (ValRS) catalytic core domain. This enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. ValRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 185677 [Multi-domain] Cd Length: 382 Bit Score: 595.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 39 PPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVERELKQtEGKSRHDLGREAFLE 118
Cdd:cd00817 1 PVFVIDTPPPNVTGSLHMGHALNNTIQDIIARYKRMKGYNVLWPPGTDHAGIATQVVVEKKLGI-EGKTRHDLGREEFLE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 119 RVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVehqe 198
Cdd:cd00817 80 KCWEWKEESGGKIREQLKRLGASVDWSREYFTMDPGLSRAVQEAFVRLYEKGLIYRDNRLVNWCPKLRTAISDIEV---- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 199 kngsiwhirypvkdtdrtltvattrpetmlgdtavavhpederyqdligkhvvlplsgreipiiadaelvdpkfgtgvvk 278
Cdd:cd00817 --------------------------------------------------------------------------------
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 279 vtpahdfndyqtglrhklpmlsildesarmtketgkyagldrfearkqvladlqeqgllekeephklsvgtCQRSTTVVE 358
Cdd:cd00817 156 -----------------------------------------------------------------------CSRSGDVIE 164
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 359 PRLSPQWFVKIEPLAKPAIEAVEQGRTKFVPESWTNTYFHWMRNIHDWCVSRQLWWGHQIPAYYCTACSPRL-GDDTDLP 437
Cdd:cd00817 165 PLLKPQWFVKVKDLAKKALEAVKEGDIKFVPERMEKRYENWLENIRDWCISRQLWWGHRIPAWYCKDGGHWVvAREEDEA 244
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 438 LDSAtvkvggvdfaraepivareQPSSCPKCGGATFIQDPDVLDTWFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHD 517
Cdd:cd00817 245 IDKA-------------------APEACVPCGGEELKQDEDVLDTWFSSSLWPFSTLGWPEETKDLKKFYPTSLLVTGHD 305
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 518 IIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKNVIDPLDVILGapadkleptlrnkfpqgmpaFGADA 597
Cdd:cd00817 306 IIFFWVARMIMRGLKLTGKLPFKEVYLHGLVRDEDGRKMSKSLGNVIDPLDVIDG--------------------YGADA 365
|
570
....*....|....*..
gi 2318732569 598 LRFTLASLTQQGRDIKL 614
Cdd:cd00817 366 LRFTLASAATQGRDINL 382
|
|
| IleS |
COG0060 |
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA ... |
15-860 |
2.28e-139 |
|
Isoleucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Isoleucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439830 [Multi-domain] Cd Length: 931 Bit Score: 448.76 E-value: 2.28e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 15 EVEARRYAFWLERNYFRA--EAPSDKPPFsmVLP--PPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTD-HaG 89
Cdd:COG0060 20 KREPEILKFWEENDIYEKsrEARAGRPKF--VLHdgPPYANGDIHIGHALNKILKDIIVRYKTMRGFDVPYVPGWDcH-G 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 90 --IATQmvVERELKQTeGKSRHDLGREAFLER----VWEWkgkfgarIGEQHRY---LGASLDWSRERFTMDEQSSAAVR 160
Cdd:COG0060 97 lpIELK--VEKELGIK-KKDIEKVGIAEFREKcreyALKY-------VDEQREDfkrLGVWGDWDNPYLTMDPEYEESIW 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 161 EVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVEHQEKNG-SIWhIRYPVKDTDRTLTVA-------TTRPETMLGDTA 232
Cdd:COG0060 167 WALKKLYEKGLLYKGLKPVPWCPRCGTALAEAEVEYKDVTSpSIY-VKFPVKDEKALLLLEdaylviwTTTPWTLPANLA 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 233 VAVHPE----------DERY---------------------------QDLIGKHVVLPLSG-----REIPIIAdAELVDP 270
Cdd:COG0060 246 VAVHPDidyvlvevtgGERLilaealveavlkelgiedyevlatfkgAELEGLRYEHPFYYvvgydRAHPVIL-GDYVTT 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 271 KFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTKETGKYAGLDRFEARKQVLADLQEQGLLEKEEPHKLSVGTC 350
Cdd:COG0060 325 EDGTGIVHTAPGHGEDDFEVGKKYGLPVLNPVDDDGRFTEEAPLFAGLFVKDANPAIIEDLKERGALLAREKITHSYPHC 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 351 QRSTTvveP---RLSPQWFVKIEPLAKPAIEAVEQgrTKFVPESWTNTYFHWMRNIHDWCVSRQLWWGHQIPAYYCTACS 427
Cdd:COG0060 405 WRCKT---PliyRATPQWFISMDKLRDRALEAIEK--VNWIPEWGEGRFGNMLENRPDWCISRQRYWGVPIPIWVCEDCG 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 428 pRLGDDTDLpLDS--ATVKVGGVD--FAR--AEPIVAREQPssCPKCGGaTFIQDPDVLDTWFSSALWPFSTLgwpRNTP 501
Cdd:COG0060 480 -ELHRTEEV-IGSvaELLEEEGADawFELdlHRPFLDETLK--CPKCGG-TMRRVPDVLDVWFDSGSMHFAVL---ENRE 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 502 ELQT---FYptsvMEtGHDII--FFWVarMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKNVIDPLDVIlgapaD 576
Cdd:COG0060 552 ELHFpadFY----LE-GSDQTrgWFYS--SLLTSTALFGRAPYKNVLTHGFVLDEDGRKMSKSLGNVVDPQEVI-----D 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 577 KleptlrnkfpqgmpaFGADALRFTLASlTQQGRDIKLSMD---RMAgyKAFcNKLWNASRFALMNMGEFTLDERPLKER 653
Cdd:COG0060 620 K---------------YGADILRLWVAS-SDYWGDLRFSDEilkEVR--DVY-RRLRNTYRFLLANLDDFDPAEDAVPYE 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 654 PLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLY--GTDEQAKDSARAVLVYSLDRI 731
Cdd:COG0060 681 DLPELDRWILSRLNELIKEVTEAYDNYDFHRAYRALHNFCVEDLSNWYLDISKDRLYteAADSLDRRAAQTTLYEVLETL 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 732 LRLLHPFMPFITEEIWQKLPMSRSvDSIMIASYPEPDADLVDEAAEAEMAPVIA-------SIEGLR---TIRgeSNLSp 801
Cdd:COG0060 761 VRLLAPILPFTAEEIWQNLPGEAE-ESVHLADWPEVDEELIDEELEAKWDLVREvrsavlkALEAARkekLIR--QPLE- 836
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....*....
gi 2318732569 802 atkvKAVVQSPDARTRELLERWRAYLMPLAGLSDVEIGAPGTKPPQAAAFVGTNLEIYV 860
Cdd:COG0060 837 ----AAVVLYADEELAAALESLGDLLAEELNVSEVELVDDAEDLGKDALKALDVEGISV 891
|
|
| PLN02843 |
PLN02843 |
isoleucyl-tRNA synthetase |
22-822 |
1.09e-82 |
|
isoleucyl-tRNA synthetase
Pssm-ID: 215452 [Multi-domain] Cd Length: 974 Bit Score: 292.83 E-value: 1.09e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 22 AFWLERNYF-RAEAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVEREL 100
Cdd:PLN02843 14 KLWEENQVYkRVSDRNNGESFTLHDGPPYANGDLHIGHALNKILKDFINRYQLLQGKKVHYVPGWDCHGLPIELKVLQSL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 101 KQtegKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLMYRAQKLIN 180
Cdd:PLN02843 94 DQ---EARKELTPIKLRAKAAKFAKKTVDTQRESFKRYGVWGDWENPYLTLDPEYEAAQIEVFGQMFLNGYIYRGRKPVH 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 181 WCPSCHTALSDLEVEHQE--KNGSIWHIrYPVKDTDRT-------------LTVATTRPETMLGDTAVAVHP-------- 237
Cdd:PLN02843 171 WSPSSRTALAEAELEYPEghVSKSIYVA-FPVVSPSETspeeleeflpglsLAIWTTTPWTMPANAAVAVNDklqysvve 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 238 -----EDERY------------------------QDLIG--------KHVVL---------------PLSGREIPIIADA 265
Cdd:PLN02843 250 vqsfsEDESTsggnkkkrpgnvlkeqqklflivaTDLVPaleakwgvKLVVLktfpgsdlegcryihPLYNRESPVVIGG 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 266 ELVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSILDESARMTKETGKYAGLDRF-EARKQVLADLQEQGLLEKEEP-- 342
Cdd:PLN02843 330 DYITTESGTGLVHTAPGHGQEDYITGLKYGLPLLSPVDDAGKFTEEAGQFSGLSVLgEGNAAVVEALDEAGSLLMEEAyg 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 343 HKLSVGTCQRSTTVVepRLSPQWFVKIEPLAKPAIEAVEQgrTKFVPESWTN--TYFHWMRNihDWCVSRQLWWGHQIPA 420
Cdd:PLN02843 410 HKYPYDWRTKKPTIF--RATEQWFASVEGFRQAALDAIDK--VKWIPAQGENriRAMVSGRS--DWCISRQRTWGVPIPV 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 421 YYCTacsprlgdDTDLPL-DSATVkvggvdfARAEPIVaREQPSSC----------P---KCGGATFIQDPDVLDTWFSS 486
Cdd:PLN02843 484 FYHV--------ETKEPLmNEETI-------AHVKSIV-AQKGSDAwwymdvedllPekyRDKASDYEKGTDTMDVWFDS 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 487 AlwpFSTLGWPRNTPELQtfYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKNVIDP 566
Cdd:PLN02843 548 G---SSWAGVLGSREGLS--YPADLYLEGSDQHRGWFQSSLLTSVATKGKAPYKSVLTHGFVLDEKGFKMSKSLGNVVDP 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 567 LDVILGAPADKLEptlrnkfpqgmPAFGADALRFTLASLTQQGrDIKLSMDRMAGYKAFCNKLWNASRFALMNMGEFtld 646
Cdd:PLN02843 623 RLVIEGGKNQKQE-----------PAYGADVLRLWVASVDYTG-DVLIGPQILKQMSDIYRKLRGTLRYLLGNLHDW--- 687
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 647 eRPLKERP---LTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLY--GTDEQAKDSAR 721
Cdd:PLN02843 688 -KPDNAVPyedLPSIDKYALFQLENVVNEIEESYDNYQFFKIFQILQRFTIVDLSNFYLDVAKDRLYvgGTTSFTRRSCQ 766
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 722 AVLVYSLDRILRLLHPFMPFITEEIWQKLPMS---RSVDSIMIASYPEPDAD-LVDEAAEAEMAPVIASIEG-----LRT 792
Cdd:PLN02843 767 TVLAAHLLSLLRAIAPILPHLAEDAWQNLPFQedgSAAESVFEAGWPTPNEEwLSFPAEDVDFWSLLLEVRDevnkvLES 846
|
890 900 910
....*....|....*....|....*....|
gi 2318732569 793 IRGESNLSPATKVKAVVQSPDARTRELLER 822
Cdd:PLN02843 847 ARNGKLIGASLEAKVYLHASDASLAARLAE 876
|
|
| Ile_Leu_Val_MetRS_core |
cd00668 |
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic ... |
40-614 |
7.05e-76 |
|
catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases; Catalytic core domain of isoleucyl, leucyl, valyl and methioninyl tRNA synthetases. These class I enzymes are all monomers. However, in some species, MetRS functions as a homodimer, as a result of an additional C-terminal domain. These enzymes aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. Enzymes in this subfamily share an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids. MetRS has a significantly shorter insertion, which lacks the editing function.
Pssm-ID: 185674 [Multi-domain] Cd Length: 312 Bit Score: 254.27 E-value: 7.05e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 40 PFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVEReLKQTEGKSRHdlgREAFLER 119
Cdd:cd00668 1 KFYVTTPPPYANGSLHLGHALTHIIADFIARYKRMRGYEVPFLPGWDTHGLPIELKAER-KGGRKKKTIW---IEEFRED 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 120 VWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLMYRaqklinwcpschtalsdlevehqek 199
Cdd:cd00668 77 PKEFVEEMSGEHKEDFRRLGISYDWSDEYITTEPEYSKAVELIFSRLYEKGLIYR------------------------- 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 200 ngsiwhirypvkdtdrtltvattrpetmlgdtavavhpederyqdliGKHVVlplsgreipiiadaelvdpkfgtgvvkv 279
Cdd:cd00668 132 -----------------------------------------------GTHPV---------------------------- 136
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 280 tpahdfndyqtglrhklpmlsildesarmtketgkyagldrfearkqvladlqeqgllekeephklsvgtcqrsttvvep 359
Cdd:cd00668 --------------------------------------------------------------------------------
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 360 RLSPQWFVKIEPLAKPAIEAVEqgRTKFVPESWTNTYFHWMRNIHDWCVSRQLWWGHQIPayyctacsprlgddtdlpld 439
Cdd:cd00668 137 RITEQWFFDMPKFKEKLLKALR--RGKIVPEHVKNRMEAWLESLLDWAISRQRYWGTPLP-------------------- 194
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 440 satvkvggvdfaraepivareqpsscpkcggatfiqdPDVLDTWFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHDII 519
Cdd:cd00668 195 -------------------------------------EDVFDVWFDSGIGPLGSLGYPEEKEWFKDSYPADWHLIGKDIL 237
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 520 FFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKNVIDPLDVIlgapadkleptlrNKfpqgmpaFGADALR 599
Cdd:cd00668 238 RGWANFWITMLVALFGEIPPKNLLVHGFVLDEGGQKMSKSKGNVIDPSDVV-------------EK-------YGADALR 297
|
570
....*....|....*
gi 2318732569 600 FTLASLTQQGRDIKL 614
Cdd:cd00668 298 YYLTSLAPYGDDIRL 312
|
|
| Anticodon_Ia_Val |
cd07962 |
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA ... |
614-750 |
1.51e-68 |
|
Anticodon-binding domain of valyl tRNA synthetases; This domain is found in valyl tRNA synthetases (ValRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. ValRS catalyzes the transfer of valine to the 3'-end of its tRNA.
Pssm-ID: 153416 [Multi-domain] Cd Length: 135 Bit Score: 226.28 E-value: 1.51e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 614 LSMDRMAGYKAFCNKLWNASRFALMNMGEFTLDERPLKerPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFL 693
Cdd:cd07962 1 FDEKRVEGGRNFCNKLWNAARFVLMNLEDDDEPEEDPE--SLSLADRWILSRLNKTVEEVTEALENYRFSEAATALYEFF 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 2318732569 694 WAEFCDWYIELAKGSLYGTDEQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKL 750
Cdd:cd07962 79 WNDFCDWYLELVKPRLYGEDEEEKKAARATLYYVLETILRLLHPFMPFITEELWQRL 135
|
|
| LeuS |
COG0495 |
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA ... |
8-774 |
4.60e-55 |
|
Leucyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Leucyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440261 [Multi-domain] Cd Length: 826 Bit Score: 207.21 E-value: 4.60e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 8 SKAYEPTEVEARRYAFWLERNYFRAEAPSDKPPF---SMvLPPPnvTGSLHIGHALTATIQDILIRWKRMSGFNAL---- 80
Cdd:COG0495 2 QERYNPKEIEKKWQKYWEENGTFKADEDSSKPKYyvlDM-FPYP--SGRLHMGHVRNYTIGDVVARYKRMQGYNVLhpmg 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 81 W----LP--------GTDHAG-----IATQmvvERELKQtegksrhdlgreaflervwewkgkfgarigeqhryLGASLD 143
Cdd:COG0495 79 WdafgLPaenaaiknGVHPAEwtyenIANM---RRQLKR-----------------------------------LGLSYD 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 144 WSRERFTMD------EQssaavrEVFVRLYEEGLMYRAQKLINWCPSCHTAL------------SDLEVEHQE------- 198
Cdd:COG0495 121 WSREIATCDpeyykwTQ------WIFLQLYEKGLAYRKEAPVNWCPVDQTVLaneqvidgrcwrCGAPVEKKElpqwflk 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 199 --------------------------KNgsiW-------HIRYPVKDTDRTLTVATTRPETMLGDTAVAV---HP----- 237
Cdd:COG0495 195 itdyadellddldkldgwpekvktmqRN---WigrsegaEVDFPVEGSDEKITVFTTRPDTLFGATFMVLapeHPlvkel 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 238 -EDERYQDL--------------------------IGKHVVLPLSGREIPI-IADAELVDpkFGTGVVKVTPAHDFNDYQ 289
Cdd:COG0495 272 aTPEQNAAVaafieeakkkseiertsetkektgvfTGLYAINPLTGEKIPIwIADYVLMD--YGTGAVMAVPAHDQRDFE 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 290 TGLRHKLPMLSIL----DESARMTKE----------TGKYAGLDRFEARKQVLADLQEQGLLEKeephklsvgtcqrstt 355
Cdd:COG0495 350 FAKKYGLPIKQVIapedGDDPDILEEaytgdgvlinSGEFDGLDSEEAKEAIIEWLEEKGLGKR---------------- 413
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 356 VVEPRLspqwfvkieplakpaieaveqgrtkfvpeswtntyfhwmrniHDWCVSRQLWWGHQIPAYYCTACSPRLGDDTD 435
Cdd:COG0495 414 KVNYRL------------------------------------------RDWLISRQRYWGEPIPIIHCEDCGVVPVPEDQ 451
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 436 LPLDSATVkvggVDF--------ARAEPIVAREqpssCPKCGGAtFIQDPDVLDTWF-SSalwpfstlgW-------PRN 499
Cdd:COG0495 452 LPVELPED----VDFdptggsplARAPEWVNVT----CPKCGGP-ARRETDTMDTFVdSS---------WyylrytdPHN 513
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 500 TPELqtFYPTSV------------MEtgHDII------FFWVArmmmmgLHFMGDV----PFRTVYLHAMVRD------- 550
Cdd:COG0495 514 DEAP--FDPEAAnywlpvdqyiggIE--HAILhllyarFFTKV------LRDLGLVsfdePFKRLLTQGMVLEvgkdgvv 583
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 551 -EKGEKMSKTKKNVIDPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASLTQQGRDIKLSMDRMAGYKAFCNKL 629
Cdd:COG0495 584 iGGIEKMSKSKGNVVDPDEII-----EK---------------YGADTLRLFEMFAGPPERDLEWSDSGVEGAYRFLNRV 643
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 630 WnasRFALMNMGEFTLDERPLKErpltlADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAefcdwyielakgsL 709
Cdd:COG0495 644 W---RLVVDEAEALKLDVADLSE-----ADKELRRALHKTIKKVTEDIERLRFNTAIAALMELVNA-------------L 702
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2318732569 710 YGTDeQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKLPMSRSVDSimiASYPEPDAD-LVDE 774
Cdd:COG0495 703 YKAK-DSGEADRAVLREALETLVLLLAPFAPHIAEELWERLGHEGSVAD---APWPEADEAaLVED 764
|
|
| PLN02882 |
PLN02882 |
aminoacyl-tRNA ligase |
7-814 |
3.54e-54 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215477 [Multi-domain] Cd Length: 1159 Bit Score: 207.27 E-value: 3.54e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 7 LSKAYEPTEVEARRYAFWLERNYF-----RAEapsDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALW 81
Cdd:PLN02882 4 EGKDFSFPKQEEKILSLWSEIDAFktqlkRTE---GLPEYIFYDGPPFATGLPHYGHILAGTIKDIVTRYQSMTGHHVTR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 82 LPGTDHAGIAtqmvVERELKQTEG-KSRHD---LG--------REAFLERVWEWKgKFGARIGeqhRYLgaslDWSRERF 149
Cdd:PLN02882 81 RFGWDCHGLP----VEYEIDKKLGiKRRDDvlkMGidkyneecRSIVTRYSKEWE-KTVTRTG---RWI----DFENDYK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 150 TMDEQSSAAVREVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVEHQEKNGSIWHI--RYP-VKDTDRTLTVA-TTRPE 225
Cdd:PLN02882 149 TMDPKFMESVWWVFKQLFEKGLVYKGFKVMPYSTACKTPLSNFEAGLNYKDVSDPAVmvSFPiVGDPDNASFVAwTTTPW 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 226 TMLGDTAVAVHPEDE--RYQDLIGKHVVLPLSGR--EIPIIAD-----------------------AELVDPKF------ 272
Cdd:PLN02882 229 TLPSNLALCVNPNFTyvKVRNKYTGKVYIVAESRlsALPTAKPkskkgskpenaaegyevlakvpgSSLVGKKYeplfdy 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 273 ---------------------GTGVVKVTPAHDFNDYQTGLRHK-------LPMlsILDESARMTKETGKYAGLDRFEAR 324
Cdd:PLN02882 309 fsefsdtafrvvaddyvtddsGTGVVHCAPAFGEDDYRVCLANGiiekggnLPV--PVDDDGCFTEKVTDFSGRYVKDAD 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 325 KQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKPAIEAVEQgrTKFVPESWTNTYFH-WMRNI 403
Cdd:PLN02882 387 KDIIAAIKAKGRLVKSGSITHSYPFCWRSDTPLIYRAVPSWFVKVEEIKDRLLENNKQ--TYWVPDYVKEKRFHnWLENA 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 404 HDWCVSRQLWWGHQIPAYyctaCSPRLGD----DTDLPLDSAT-VKVggVDFARaEPIVAREQPSS-CPKCGGATFIQDp 477
Cdd:PLN02882 465 RDWAVSRSRFWGTPLPIW----ISDDGEEvvviGSIAELEKLSgVKV--TDLHR-HFIDHITIPSSrGPEFGVLRRVDD- 536
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 478 dVLDTWFSSALWPFSTLGWPRNTPEL-QTFYPTSVMETGHDIIFFWVARMMMMGLHFMGDVPFRTVYLHAMVRDEKGEKM 556
Cdd:PLN02882 537 -VFDCWFESGSMPYAYIHYPFENKELfEKNFPADFVAEGLDQTRGWFYTLMVLSTALFDKPAFKNLICNGLVLAEDGKKM 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 557 SKTKKNVIDPLDVILGAPADKLEPTLRNKfpqgmPAFGADALRFTLASLTQQGRDIKLSMdrmagYKAFCNKLWNASRFA 636
Cdd:PLN02882 616 SKSLKNYPDPNEVIDKYGADALRLYLINS-----PVVRAEPLRFKEEGVFGVVKDVFLPW-----YNAYRFLVQNAKRLE 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 637 LMNMGEFT-LDERPLKERPLTLaDRWILSRLQRATTEARASLETYGFAEAASTLYQFLwAEFCDWYIELAKGSLYG-TDE 714
Cdd:PLN02882 686 VEGGAPFVpLDLAKLQNSANVL-DRWINSATQSLVKFVREEMGAYRLYTVVPYLVKFI-DNLTNIYVRFNRKRLKGrTGE 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 715 QAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKL--PMSRSVDSIMIASYPEPDADLVDEAAEAEMAPVIASIEGLRT 792
Cdd:PLN02882 764 EDCRTALSTLYNVLLTSCKVMAPFTPFFTEVLYQNLrkVLPGSEESIHYCSFPQVDEGELDERIEQSVSRMQTVIELARN 843
|
890 900
....*....|....*....|...
gi 2318732569 793 IRGESNLSPATKVKA-VVQSPDA 814
Cdd:PLN02882 844 IRERHNKPLKTPLKEmVVVHPDA 866
|
|
| leuS |
PRK12300 |
leucyl-tRNA synthetase; Reviewed |
54-793 |
9.83e-51 |
|
leucyl-tRNA synthetase; Reviewed
Pssm-ID: 237049 [Multi-domain] Cd Length: 897 Bit Score: 194.70 E-value: 9.83e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 54 LHIGHALTATIQDILIRWKRMSGFNALWlP------GTDHAGIAtQMVVERELKQTEG-KSRHDLGREAfLERV---WEW 123
Cdd:PRK12300 1 LHVGHGRTYTIGDVIARYKRMRGYNVLF-PmafhvtGTPILGIA-ERIARGDPETIELyKSLYGIPEEE-LEKFkdpEYI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 124 KGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLMYRAQKLINWCPSCHTA------LSDLEVEHQ 197
Cdd:PRK12300 78 VEYFSEEAKEDMKRIGYSIDWRREFTTTDPEYSKFIEWQFRKLKEKGLIVKGSHPVRYCPNDNNPvgdhdlLDGEEPEIV 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 198 EkngsiWHIRYPVKDTDRTLTVATTRPETMLGDTAVAVHPEDE---------------------RYQD------------ 244
Cdd:PRK12300 158 E-----YTLIKFEESEDLILPAATLRPETIFGVTNLWVNPDATyvkaevdgekwivskeaaeklSFQDrdveiieeikgs 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 245 -LIGKHVVLPLSGREIPIIAdAELVDPKFGTGVVKVTPAHDFNDYqTGLRH-----------------------KLPMLS 300
Cdd:PRK12300 233 eLIGKKVKNPVTGKEVPILP-ADFVDPDNGTGVVMSVPAHAPYDY-VALRDlkknkelldviepiplievegygEFPAKE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 301 I-------------LDESAR-----------MTKETGKYAGLDRFEARKQVLADLQEQGLLEK--EEPHKLSVgtCQRST 354
Cdd:PRK12300 311 VveklgiksqedpeLEEATKevyraefhkgvLKENTGEYAGKPVREAREKITKDLIEKGIADImyEFSNRPVY--CRCGT 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 355 TVVEPRLSPQWFVKI-EP----LAKPAIEaveqgRTKFVPESwtntYFHWMRNIHDWCVSRqlwwghqipayyctACSPR 429
Cdd:PRK12300 389 ECVVKVVKDQWFIDYsDPewkeLAHKALD-----NMEIIPEE----YRKEFENTIDWLKDR--------------ACARR 445
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 430 LGDDTDLPLDSATVkvggvdfarAEP-----------IVAReqpsscpkcggatFIQ---------DPDVLDTWF---SS 486
Cdd:PRK12300 446 RGLGTRLPWDEEWI---------IESlsdstiymayyTIAH-------------KIReygikpeqlTPEFFDYVFlgkGD 503
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 487 ALWPFSTLGWPRNT-----PELQTFYPTSVMETGHDII-----FF------------WVARMMMMGlhfmgdvpfrtvyl 544
Cdd:PRK12300 504 PEEVSKKTGIPKEIleemrEEFLYWYPVDWRHSGKDLIpnhltFFifnhvaifpeekWPRGIVVNG-------------- 569
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 545 haMVRDEkGEKMSKTKKNVIDPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASLTQQGRDiklsMDrmagyka 624
Cdd:PRK12300 570 --FVLLE-GKKMSKSKGNVIPLRKAI-----EE---------------YGADVVRLYLTSSAELLQD----AD------- 615
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 625 FCNKLWNASRFALMNMGEFTLDERPLK-ERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFcDWYIE 703
Cdd:PRK12300 616 WREKEVESVRRQLERFYELAKELIEIGgEEELRFIDKWLLSRLNRIIKETTEAMESFQTRDAVQEAFYELLNDL-RWYLR 694
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 704 LAKgslygtdeqakDSARAVLVYSLDRILRLLHPFMPFITEEIWQKLpmsRSVDSIMIASYPEPDADLVDEAAEAEMAPV 783
Cdd:PRK12300 695 RVG-----------EANNKVLREVLEIWIRLLAPFTPHLAEELWHKL---GGEGFVSLEKWPEPDESKIDEEAELAEEYV 760
|
890
....*....|
gi 2318732569 784 IASIEGLRTI 793
Cdd:PRK12300 761 KRLIEDIREI 770
|
|
| Anticodon_1 |
pfam08264 |
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA ... |
659-809 |
5.38e-45 |
|
Anticodon-binding domain of tRNA ligase; This domain is found mainly hydrophobic tRNA synthetases. The domain binds to the anticodon of the tRNA ligase.
Pssm-ID: 400523 [Multi-domain] Cd Length: 141 Bit Score: 159.11 E-value: 5.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 659 DRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKGSLYGTDEQAKdsARAVLVYSLDRILRLLHPF 738
Cdd:pfam08264 1 DRWILSRLNKLIKEVTEAYENYRFNTAAQALYEFFWNDLSDWYLELIKDRLYGEEPDSR--AQTTLYEVLETLLRLLAPF 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2318732569 739 MPFITEEIWQKlpmsrsvDSIMIASYPEpDADLVDEAAEAEMAPVIASIEGLRTIRGESNLSPATKVKAVV 809
Cdd:pfam08264 79 MPFITEELWQK-------ESIHLAPWPE-DAELEEAELEEAFELRQEIVQAIRKLRSELKIKKSLPLEVVI 141
|
|
| IleRS_core |
cd00818 |
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases ... |
47-614 |
3.99e-42 |
|
catalytic core domain of isoleucyl-tRNA synthetases; Isoleucine amino-acyl tRNA synthetases (IleRS) catalytic core domain . This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. IleRS has an insertion in the core domain, which is subject to both deletions and rearrangements. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173909 [Multi-domain] Cd Length: 338 Bit Score: 157.78 E-value: 3.99e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 47 PPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVERELKQTEGKSRHDLGREAFLERVWEWKGK 126
Cdd:cd00818 9 PPYANGLPHYGHALNKILKDIINRYKTMQGYYVPRRPGWDCHGLPIELKVEKELGISGKKDIEKMGIAEFNAKCREFALR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 127 FGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLMYRAQKLINWcpschtalsdlevehqekngsiwhi 206
Cdd:cd00818 89 YVDEQEEQFQRLGVWVDWENPYKTMDPEYMESVWWVFKQLHEKGLLYRGYKVVPW------------------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 207 rypvkdtdrtltvattrpetmlgdtavavhpederyqdligkhvvlplsgreiPIIadaelvdpkfgtgvvkvtpahdfn 286
Cdd:cd00818 144 -----------------------------------------------------PLI------------------------ 146
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 287 dyqtglrhklpmlsildesarmtketgkYagldrfearkqvladlqeqgllekeephklsvgtcqrsttvvepRLSPQWF 366
Cdd:cd00818 147 ----------------------------Y--------------------------------------------RATPQWF 154
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 367 VKIEPLAKPAIEAVEQgrTKFVPESWTNTYFHWMRNIHDWCVSRQLWWGHQIPAYYCTACSprlgddtdlpldsatvkvg 446
Cdd:cd00818 155 IRVTKIKDRLLEANDK--VNWIPEWVKNRFGNWLENRRDWCISRQRYWGTPIPVWYCEDCG------------------- 213
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 447 gvdfaraEPIVAREqpsscpkcggatfiqdPDVLDTWFSSALWPFSTLGWPRNTPELQTFYPTSVMETGHDIIFFWVARM 526
Cdd:cd00818 214 -------EVLVRRV----------------PDVLDVWFDSGSMPYAQLHYPFENEDFEELFPADFILEGSDQTRGWFYSL 270
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 527 MMMGLHFMGDVPFRTVYLHAMVRDEKGEKMSKTKKNVIDPLDVilgapadkleptlrnkfpqgMPAFGADALRFTLASLT 606
Cdd:cd00818 271 LLLSTALFGKAPYKNVIVHGFVLDEDGRKMSKSLGNYVDPQEV--------------------VDKYGADALRLWVASSD 330
|
....*...
gi 2318732569 607 QQGRDIKL 614
Cdd:cd00818 331 VYAEDLRF 338
|
|
| PTZ00427 |
PTZ00427 |
isoleucine-tRNA ligase, putative; Provisional |
15-750 |
5.87e-37 |
|
isoleucine-tRNA ligase, putative; Provisional
Pssm-ID: 173617 [Multi-domain] Cd Length: 1205 Bit Score: 152.04 E-value: 5.87e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 15 EVEARRYAFWLERNYFRA--EAPSDKPPFSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIAT 92
Cdd:PTZ00427 76 EEEEKVLKYWKSIDAFNTsnKLAKNKKAYIFYDGPPFATGLPHYGHLLAGIIKDCVTRYFYQCGFSVERKFGWDCHGLPI 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 93 QMVVERELKQTEGKSRHDLGREAFLERVWEWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLM 172
Cdd:PTZ00427 156 EYEIEKENNINKKEDILKMGIDVYNEKCRGIVLKYSNEWVKTVERIGRWIDFKNDYKTMDKTFMESVWWVFSELYKNNYV 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 173 YRAQKLINWCPSCHTALSDLEVEHQEKN--------------------------------GSIWHIRYPVKDTDRT---- 216
Cdd:PTZ00427 236 YKSFKVMPYSCKCNTPISNFELNLNYKDtpdpsiiisfvlcsdfpkveeecnieedkqllGEKYSVLYNNKRENSNngnn 315
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 217 -------------LTVATTRPETMLGDTAVAV----------HPEDERY-------------------QDL------IGK 248
Cdd:PTZ00427 316 nstnnvcyaqhseILAWTTTPWTLPSNLALCVnehftylrihHVKSNRVvivgecrlewimkelkwnvEDLkivnrfKGK 395
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 249 HV----VLPLSG----------REIPIIADaELVDPKFGTGVVKVTPAHDFNDYQTGLRHKL--PMLSI----LDESARM 308
Cdd:PTZ00427 396 ELkglrYKPLFTnfyekynfkeRAYKILAD-DFVTDDAGTGIVHCAPTYGEDDFRVCKKNGVidPEKNIfidpLDANGYF 474
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 309 TKETGKYAGLDRFEARKQVLADLQEQGLLEKEEPHKLSVGTCQRSTTVVEPRLSPQWFVKIEPLAKpaiEAVEQGRTKF- 387
Cdd:PTZ00427 475 TNEVEEVQNLYIKEADNVIKKKLKNENRLLSNNTIVHSYPFCWRSDTPLIYRAIPAWFIRVSNSTN---ELVKNNETTYw 551
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 388 VPESWTNTYFH-WMRNIHDWCVSRQLWWGHQIPAYyctaCSPRLgdDTDLPLDSAT--VKVGGV----DFAR--AEPI-V 457
Cdd:PTZ00427 552 IPAHIKEKKFHnWIKDAKDWCISRNRYWGTPIPIW----ADEKM--ETVICVESIKhlEELSGVkninDLHRhfIDHIeI 625
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 458 AREQPSSCPKcggatFIQDPDVLDTWFSSALWPFSTLGWPRNTP--ELQTFYPTSVMETGHDIIFFWVARMMMMGLHFMG 535
Cdd:PTZ00427 626 KNPKGKTYPK-----LKRIPEVFDCWFESGSMPYAKVHYPFSTEkeDFHKIFPADFIAEGLDQTRGWFYTLLVISTLLFD 700
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 536 DVPFRTVYLHAMVRDEKGEKMSKTKKNVIDPLDVILGAPADKLEPTLRNKFpqgmpAFGADALRFTLASLTQQGRDIKLS 615
Cdd:PTZ00427 701 KAPFKNLICNGLVLASDGKKMSKRLKNYPDPLYILDKYGADSLRLYLINSV-----AVRAENLKFQEKGVNEVVKSFILP 775
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 616 MdrmagYKAFCNKLWNASRFALMNMGEFTLDERPLKERPlTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLwA 695
Cdd:PTZ00427 776 F-----YHSFRFFSQEVTRYECLNKKQFLFNTDYIYKND-NIMDQWIFSSVQSLTKSVHTEMKAYKLYNVLPKLLQFI-E 848
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*.
gi 2318732569 696 EFCDWYIELAKGSLYGT-DEQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKL 750
Cdd:PTZ00427 849 NLTNWYIRLNRDRMRGSlGEENCLQSLCTTYRTLHLFTVLMAPFTPFITEYIYQQL 904
|
|
| PLN02563 |
PLN02563 |
aminoacyl-tRNA ligase |
4-774 |
1.40e-33 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178177 [Multi-domain] Cd Length: 963 Bit Score: 140.73 E-value: 1.40e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 4 TTELSKAYEPTEVEARRYAFWLERNYFRA--EAPSDKPPFSMV--LPPPNVTGsLHIGHALTATIQDILIRWKRMSGFNA 79
Cdd:PLN02563 73 TPAAKRAYPFHEIEPKWQRYWEENRTFRTpdDVDTSKPKFYVLdmFPYPSGAG-LHVGHPEGYTATDILARYKRMQGYNV 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 80 LWLPGTDHAGI-ATQMVVERELKQTEGKSRHDlgreaflervwewkgkfgARIGEQHRYLGASLDWSRERFTMDEQSSAA 158
Cdd:PLN02563 152 LHPMGWDAFGLpAEQYAIETGTHPKITTLKNI------------------ARFRSQLKSLGFSYDWDREISTTEPEYYKW 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 159 VREVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVEH--QEKNG---------------------------------SI 203
Cdd:PLN02563 214 TQWIFLQLLKRGLAYQAEVPVNWCPALGTVLANEEVVDglSERGGhpvirkpmrqwmlkitayadrlledlddldwpeSI 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 204 ------W-------HIRYPV-----KDTDRTLTVATTRPETMLGDTAVAVHPED---------------ERYQDL----- 245
Cdd:PLN02563 294 kemqrnWigrsegaELDFSVldgegKERDEKITVYTTRPDTLFGATYLVVAPEHpllsslttaeqkeavEEYVDAasrks 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 246 ---------------IGKHVVLPLSGREIPI-IADaeLVDPKFGTGVVKVTPAHDFNDYQTGLRHKLPMLSI-------L 302
Cdd:PLN02563 374 dlertelqkektgvfTGSYAINPATGEAIPIwVAD--YVLGSYGTGAIMAVPAHDTRDFEFAQKFDLPIKWVvkpadgnE 451
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 303 DESARMTKETGK----------YAGLDRFEARKQVLADLQEQGLLEKEEPHKLsvgtcqrsttvveprlspqwfvkiepl 372
Cdd:PLN02563 452 DDAEKAYTGEGVivnssssgldINGLSSKEAAKKVIEWLEETGNGKKKVNYKL--------------------------- 504
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 373 akpaieaveqgrtkfvpeswtntyfhwmrniHDWCVSRQLWWGHQIPAYYCTACSPRLG-DDTDLPL------DSATVKV 445
Cdd:PLN02563 505 -------------------------------RDWLFARQRYWGEPIPVVFLEDSGEPVPvPESDLPLtlpeldDFTPTGT 553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 446 GGVDFARAEPIVAREQPSScpkcgGATFIQDPDVLDTWFSSAlWPFSTLGWPRNT-----PELQTFY-PTSVMETG--HD 517
Cdd:PLN02563 554 GEPPLAKAVSWVNTVDPSS-----GKPARRETNTMPQWAGSC-WYYLRFMDPKNSnalvdKEKEKYWmPVDLYVGGaeHA 627
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 518 IIFFWVARMMMMGLHFMGDV----PFRTVYLHAMV---------RDEKGE------------------------------ 554
Cdd:PLN02563 628 VLHLLYARFWHKVLYDIGVVstkePFQCLVNQGMIlgeveytafKDSDGEyvsadtadrlgelqqekipeekviksgdsf 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 555 ---------------KMSKTKKNVIDPLDVILgapadkleptlrnkfpqgmpAFGADALRFT---LASLtqqgRDIKL-S 615
Cdd:PLN02563 708 vlkddpsirliarahKMSKSRGNVVNPDDVVS--------------------EYGADSLRLYemfMGPL----RDSKTwS 763
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 616 MDRMAGYKAFCNKLWNASRFALMNMGEFTLDERPLKERPltlaDRWILSRLQRATTEARASLETYGFAEAASTLYQFLWA 695
Cdd:PLN02563 764 TSGVEGVHRFLGRTWRLVVGAPLPDGSFRDGTVVTDEEP----SLEQLRLLHKCIAKVTEEIESTRFNTAISAMMEFTNA 839
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2318732569 696 efcdwyielakgsLYGTDEQAKDSARAVLVysldrilrLLHPFMPFITEEIWQKLPMSrsvDSIMIASYPEPDADLVDE 774
Cdd:PLN02563 840 -------------AYKWDKVPREAIEPFVL--------LLSPYAPHLAEELWFRLGHS---NSLAYEPWPEANPSYLVD 894
|
|
| Anticodon_Ia_Ile_ABEc |
cd07961 |
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA ... |
623-788 |
1.56e-32 |
|
Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial, archaeal, and eukaryotic cytoplasmic members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153415 [Multi-domain] Cd Length: 183 Bit Score: 124.97 E-value: 1.56e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 623 KAFCNKLWNASRFALMNMG----EFTLDERPLKERPLTlaDRWILSRLQRATTEARASLETYGFAEAASTLYQFLwAEFC 698
Cdd:cd07961 11 RKVLLPLWNAYRFFVTYANldgfDPGKDDDAVASLNVL--DRWILSRLNSLIKEVTEEMEAYDLYTAVRALLEFI-DELT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 699 DWYIELAKGSLYGT-DEQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKL--PMSRSVDSIMIASYPEPDADLVDEA 775
Cdd:cd07961 88 NWYIRRNRKRFWGEeGDDDKLAAYATLYEVLLTLSRLMAPFTPFITEEIYQNLrrELGDAPESVHLLDWPEVDESLIDEE 167
|
170
....*....|...
gi 2318732569 776 AEAEMAPVIASIE 788
Cdd:cd07961 168 LEEAMELVREIVE 180
|
|
| Anticodon_Ia_Ile_BEm |
cd07960 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; ... |
628-796 |
4.71e-25 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; This domain is found in isoleucyl tRNA synthetases (IleRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon. This family includes bacterial and eukaryotic mitochondrial members. IleRS catalyzes the transfer of isoleucine to the 3'-end of its tRNA.
Pssm-ID: 153414 [Multi-domain] Cd Length: 180 Bit Score: 103.37 E-value: 4.71e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 628 KLWNASRFALMNMGEFTLDERPLKERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFCDWYIELAKG 707
Cdd:cd07960 15 KIRNTFRFLLGNLNDFDPAKDAVPYEELLELDRYALHRLNELIKEVREAYENYEFHKVYQALNNFCTVDLSAFYLDIIKD 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 708 SLYgTDeqAKDS-----ARAVLVYSLDRILRLLHPFMPFITEEIWQKLPMSRSVDSIMIASYPEPDADLVDEAAEAEMap 782
Cdd:cd07960 95 RLY-CD--AKDSlerrsAQTVLYHILDALLKLLAPILPFTAEEVWEHLPGEKKEESVFLEDWPELPEEWKDEELEEKW-- 169
|
170
....*....|....
gi 2318732569 783 viasiEGLRTIRGE 796
Cdd:cd07960 170 -----EKLLALRDE 178
|
|
| Val_tRNA-synt_C |
pfam10458 |
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA ... |
867-931 |
4.13e-19 |
|
Valyl tRNA synthetase tRNA binding arm; This domain is found at the C-terminus of Valyl tRNA synthetases.
Pssm-ID: 431296 [Multi-domain] Cd Length: 66 Bit Score: 82.31 E-value: 4.13e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2318732569 867 DLDAERDRLRKEIARTEQEAAGVLRKLENPNFVAKAPPDVVEKDRARVEELKERKAKLQDHLQRI 931
Cdd:pfam10458 1 DVEKERARLEKELAKLQKEIERVQGKLANPGFVAKAPAEVVEEEKAKLAELEEQAEKLRERLSKL 65
|
|
| LeuRS_core |
cd00812 |
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic ... |
43-182 |
6.82e-17 |
|
catalytic core domain of leucyl-tRNA synthetases; Leucyl tRNA synthetase (LeuRS) catalytic core domain. This class I enzyme is a monomer which aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. In Aquifex aeolicus, the gene encoding LeuRS is split in two, just before the KMSKS motif. Consequently, LeuRS is a heterodimer, which likely superimposes with the LeuRS monomer found in most other organisms. LeuRS has an insertion in the core domain, which is subject to both deletions and rearrangements and thus differs between prokaryotic LeuRS and archaeal/eukaryotic LeuRS. This editing region hydrolyzes mischarged cognate tRNAs and thus prevents the incorporation of chemically similar amino acids.
Pssm-ID: 173906 [Multi-domain] Cd Length: 314 Bit Score: 83.07 E-value: 6.82e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 43 MVLPP-PNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDhagiATQMVVE---RELKQTEGKsrhdlgreafle 118
Cdd:cd00812 3 YILVMfPYPSGALHVGHVRTYTIGDIIARYKRMQGYNVLFPMGFD----AFGLPAEnaaIKIGRDPED------------ 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2318732569 119 rvweWKGKFGARIGEQHRYLGASLDWSRERFTMDEQSSAAVREVFVRLYEEGLMYRAQKLINWC 182
Cdd:cd00812 67 ----WTEYNIKKMKEQLKRMGFSYDWRREFTTCDPEYYKFTQWLFLKLYEKGLAYKKEAPVNWC 126
|
|
| MetG |
COG0143 |
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA ... |
492-750 |
3.31e-16 |
|
Methionyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Methionyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439913 [Multi-domain] Cd Length: 544 Bit Score: 83.62 E-value: 3.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 492 STLGWPRNT---PELQTFYPTSVMETGH----DIIFF----WVArmMMMGLHFmgDVPfRTVYLHAMVRDEkGEKMSKTK 560
Cdd:COG0143 259 ATKGYADDRglpEDFEKYWPAPDTELVHfigkDIIRFhaiiWPA--MLMAAGL--PLP-KKVFAHGFLTVE-GEKMSKSR 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 561 KNVIDPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASLTQQGRDIKLSMDRMAgykAFCN-----KLWN-ASR 634
Cdd:COG0143 333 GNVIDPDDLL-----DR---------------YGPDALRYYLLREVPFGQDGDFSWEDFV---ARVNsdlanDLGNlASR 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 635 FALMNMGEFtlDERPLKERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFlwAEFCDWYIE------LAKgs 708
Cdd:COG0143 390 TLSMIHKYF--DGKVPEPGELTEADEELLAEAEAALEEVAEAMEAFEFRKALEEIMAL--ARAANKYIDetapwkLAK-- 463
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2318732569 709 lygtdEQAKDSARAVLvYSLDRILR----LLHPFMPFITEEIWQKL 750
Cdd:COG0143 464 -----DEDPERLATVL-YTLLEALRilaiLLKPFLPETAEKILEQL 503
|
|
| Anticodon_Ia_like |
cd07375 |
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This ... |
618-739 |
1.28e-14 |
|
Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; This domain is found in a variety of class Ia aminoacyl tRNA synthetases, C-terminal to the catalytic core domain. It recognizes and specifically binds to the anticodon of the tRNA. Aminoacyl tRNA synthetases catalyze the transfer of cognate amino acids to the 3'-end of their tRNAs by specifically recognizing cognate from non-cognate amino acids. Members include valyl-, leucyl-, isoleucyl-, cysteinyl-, arginyl-, and methionyl-tRNA synthethases. This superfamily also includes a domain from MshC, an enzyme in the mycothiol biosynthetic pathway.
Pssm-ID: 153408 [Multi-domain] Cd Length: 117 Bit Score: 71.38 E-value: 1.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 618 RMAGYKAFCNKLWNASRFALMNMGEFTLDERPLKerpLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEf 697
Cdd:cd07375 3 RLKQARAFLNRLYRLLSFFRKALGGTQPKWDNEL---LEEADRELLARLQEFIKRTTNALEALDPTTAVQELFKFTNEL- 78
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2318732569 698 cDWYIELAKGSLYGTDEQAKdsARAVLVYSLDRILRLLHPFM 739
Cdd:cd07375 79 -NWYLDELKPALQTEELREA--VLAVLRAALVVLTKLLAPFT 117
|
|
| PRK11893 |
PRK11893 |
methionyl-tRNA synthetase; Reviewed |
475-750 |
6.32e-14 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237012 [Multi-domain] Cd Length: 511 Bit Score: 76.07 E-value: 6.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 475 QDPD-VLDTWFSsALWPF-STLGWPRNTPELQT----FYPTSVMETGHDIIFF----WVARMMMMGLHFmgdvpFRTVYL 544
Cdd:PRK11893 216 GDPKhVIYVWFD-ALTNYlTALGYPDDEELLAElfnkYWPADVHLIGKDILRFhavyWPAFLMAAGLPL-----PKRVFA 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 545 HAMVRDEkGEKMSKTKKNVIDPLDVIlgapaDKleptlrnkfpqgmpaFGADALRFTLASLTQQGRDIKLSMDRMAG-YK 623
Cdd:PRK11893 290 HGFLTLD-GEKMSKSLGNVIDPFDLV-----DE---------------YGVDAVRYFLLREIPFGQDGDFSREAFINrIN 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 624 A-FCNKLWN-ASRFALMNMGEFtlDERPLKERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQflWAEFCDWY 701
Cdd:PRK11893 349 AdLANDLGNlAQRTLSMIAKNF--DGKVPEPGALTEADEALLEAAAALLERVRAAMDNLAFDKALEAILA--LVRAANKY 424
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 2318732569 702 I-ELAKGSLYGTDEQAKDSARAVLVYSLDRILRLLHPFMPFITEEIWQKL 750
Cdd:PRK11893 425 IdEQAPWSLAKTDPERLATVLYTLLEVLRGIAVLLQPVMPELAAKILDQL 474
|
|
| metG |
TIGR00398 |
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ... |
46-750 |
8.03e-14 |
|
methionine--tRNA ligase; The methionyl-tRNA synthetase (metG) is a class I amino acyl-tRNA ligase. This model appears to recognize the methionyl-tRNA synthetase of every species, including eukaryotic cytosolic and mitochondrial forms. The UPGMA difference tree calculated after search and alignment according to this model shows an unusual deep split between two families of MetG. One family contains forms from the Archaea, yeast cytosol, spirochetes, and E. coli, among others. The other family includes forms from yeast mitochondrion, Synechocystis sp., Bacillus subtilis, the Mycoplasmas, Aquifex aeolicus, and Helicobacter pylori. The E. coli enzyme is homodimeric, although monomeric forms can be prepared that are fully active. Activity of this enzyme in bacteria includes aminoacylation of fMet-tRNA with Met; subsequent formylation of the Met to fMet is catalyzed by a separate enzyme. Note that the protein from Aquifex aeolicus is split into an alpha (large) and beta (small) subunit; this model does not include the C-terminal region corresponding to the beta chain. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273058 [Multi-domain] Cd Length: 530 Bit Score: 75.88 E-value: 8.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 46 PPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVERELKQTEgksrhdlgreaflervwewkg 125
Cdd:TIGR00398 6 ALPYANGKPHLGHAYTTILADVYARYKRLRGYEVLFVCGTDEHGTKIELKAEQEGLTPK--------------------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 126 KFGARIGEQHRYLGASLDWSRERF--TMDEQSSAAVREVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVE-HQEKNGS 202
Cdd:TIGR00398 65 ELVDKYHEEFKDDWKWLNISFDRFirTTDEEHKEIVQKIFQKLKENGYIYEKEIKQLYCPECEMFLPDRYVEgTCPKCGS 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 203 iwhirypvkdtdrtltvattrpETMLGDTAvavhpederyqdligkhvvlplsgreipiiadaelvdpkfgtgvvkvtpa 282
Cdd:TIGR00398 145 ----------------------EDARGDHC-------------------------------------------------- 152
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 283 hdfndyqtglrhklpmlsildesarmtketgkyagldrfearkQVLADLQEQGLLEKEEphklsvgtCQRSTTVVEPRLS 362
Cdd:TIGR00398 153 -------------------------------------------EVCGRHLEPTELINPR--------CKICGAKPELRDS 181
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 363 PQWFVKIEPLAKPAIEAVEQGRT-KFVPESWTNTYFHWMRN-IHDWCVSRQL-WWGHQIPayyctacsprlgddtdlpld 439
Cdd:TIGR00398 182 EHYFFRLSAFEKELEEWIRKNPEsGSPASNVKNKAQNWLKGgLKDLAITRDLvYWGIPVP-------------------- 241
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 440 satvkvggvdfaraepivareqpsscpkcggatfiQDPD-VLDTWFSSALWPFSTLGWPRN-TPELQTFYPTSVMET--- 514
Cdd:TIGR00398 242 -----------------------------------NDPNkVVYVWFDALIGYISSLGILSGdTEDWKKWWNNDEDAElih 286
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 515 --GHDIIFF----WVArmMMMGLHFmgdVPFRTVYLHAMVRDEkGEKMSKTKKNVIDPLDVILGapadkleptlrnkfpq 588
Cdd:TIGR00398 287 fiGKDIVRFhtiyWPA--MLMGLGL---PLPTQVFSHGYLTVE-GGKMSKSLGNVVDPSDLLAR---------------- 344
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 589 gmpaFGADALRFTLASLTQQGRDIKLSMDR-MAGYKA-FCNKLWN-ASRFALMNMGEFtlDERPLKERPLTLADRWILSR 665
Cdd:TIGR00398 345 ----FGADILRYYLLKERPLGKDGDFSWEDfVERVNAdLANKLGNlLNRTLGFIKKYF--NGVLPSEDITDEEDKKLLKL 418
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 666 LQRATTEARASLETYGFAEAASTLYQF------LWAEFCDWyiELAKgslygtDEQAKDSARAVLVYSLDRILRLLHPFM 739
Cdd:TIGR00398 419 INEALEQIDEAIESFEFRKALREIMKLadrgnkYIDENKPW--ELFK------QSPRLKELLAVCSMLIRVLSILLYPIM 490
|
730
....*....|.
gi 2318732569 740 PFITEEIWQKL 750
Cdd:TIGR00398 491 PKLSEKILKFL 501
|
|
| Anticodon_Ia_Leu_AEc |
cd07959 |
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This ... |
654-750 |
1.58e-13 |
|
Anticodon-binding domain of archaeal and eukaryotic cytoplasmic leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes archaeal and eukaryotic cytoplasmic members. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153413 [Multi-domain] Cd Length: 117 Bit Score: 68.39 E-value: 1.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 654 PLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLWAEFcDWYIELAKGslygtdeqakDSARAVLVYSLDRILR 733
Cdd:cd07959 32 ELTFIDRWLLSRLNRLIKETTEAYENMQFREALKEGLYELQNDL-DWYRERGGA----------GMNKDLLRRFIEVWTR 100
|
90
....*....|....*..
gi 2318732569 734 LLHPFMPFITEEIWQKL 750
Cdd:cd07959 101 LLAPFAPHLAEEIWHEL 117
|
|
| tRNA-synt_1g |
pfam09334 |
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases. |
48-195 |
3.82e-13 |
|
tRNA synthetases class I (M); This family includes methionyl tRNA synthetases.
Pssm-ID: 401322 [Multi-domain] Cd Length: 387 Bit Score: 72.71 E-value: 3.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 48 PNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVERelkqtEGKSRHDLgreaflervwewkgkf 127
Cdd:pfam09334 8 PYANGPPHLGHLYSYIPADIFARYLRLRGYDVLFVCGTDEHGTPIELKAEK-----EGITPEEL---------------- 66
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 128 GARIGEQHRYLGASLDWSRERF--TMDEQSSAAVREVFVRLYEEGLMYRAQKLINWCPSCHTALSDLEVE 195
Cdd:pfam09334 67 VDRYHEIHREDFKKFNISFDDYgrTTSERHHELVQEFFLKLYENGYIYEKEIEQFYCPSDERFLPDRYVE 136
|
|
| tRNA-synt_1_2 |
pfam13603 |
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ... |
206-331 |
5.91e-12 |
|
Leucyl-tRNA synthetase, Domain 2; This is a family of the conserved region of Leucine-tRNA ligase or Leucyl-tRNA synthetase, EC:6.1.1.4.
Pssm-ID: 433342 [Multi-domain] Cd Length: 185 Bit Score: 65.65 E-value: 5.91e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 206 IRYPVKDTDRTLTVATTRPETMLGDTAVAVHPE----------DERYQDLI-----------------------GKHVVL 252
Cdd:pfam13603 12 ITFPVEGTDEKIEVFTTRPDTLMGVTFVALAPEhplveklaekNPEVAAFIeeckntseiertsetkekegvftGLYAIH 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 253 PLSGREIPI-IADAELVDpkFGTGVVKVTPAHDFNDYQTGLRHKLPM----------LSILDESARMTKET-----GKYA 316
Cdd:pfam13603 92 PITGEKIPIwIANFVLME--YGTGAVMAVPAHDQRDFEFAKKYNLPIkpviqpedgdLDLDIMTEAYTEEGilvnsGEFD 169
|
170
....*....|....*
gi 2318732569 317 GLDRFEARKQVLADL 331
Cdd:pfam13603 170 GLDSEEAKEAIIKKL 184
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
492-750 |
1.10e-11 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 69.44 E-value: 1.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 492 STLGWPRNTPEL-QTFYPTSVMETGHDII-F---FWVARMMMMGLHfmgdvPFRTVYLHA---MvrdeKGEKMSKTKKNV 563
Cdd:PRK12267 237 TALGYGSDDDELfKKFWPADVHLVGKDILrFhaiYWPIMLMALGLP-----LPKKVFAHGwwlM----KDGKMSKSKGNV 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 564 IDPLDVIlgapadkleptlrnkfpqgmPAFGADALRFTLAsltqqgRDIKLSMDRMAGYKAF--------CNKLWNasrf 635
Cdd:PRK12267 308 VDPEELV--------------------DRYGLDALRYYLL------REVPFGSDGDFSPEALverinsdlANDLGN---- 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 636 aLMN----MGEFTLDERPLKERPLTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFLwaEFCDWYIE------LA 705
Cdd:PRK12267 358 -LLNrtvaMINKYFDGEIPAPGNVTEFDEELIALAEETLKNYEELMEELQFSRALEEVWKLI--SRANKYIDetapwvLA 434
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 2318732569 706 KgslygtDEQAKDSARAVLvYSLDRILR----LLHPFMPFITEEIWQKL 750
Cdd:PRK12267 435 K------DEGKKERLATVM-YHLAESLRkvavLLSPFMPETSKKIFEQL 476
|
|
| MetRS_core |
cd00814 |
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) ... |
48-185 |
4.97e-11 |
|
catalytic core domain of methioninyl-tRNA synthetases; Methionine tRNA synthetase (MetRS) catalytic core domain. This class I enzyme aminoacylates the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. MetRS, which consists of the core domain and an anti-codon binding domain, functions as a monomer. However, in some species the anti-codon binding domain is followed by an EMAP domain. In this case, MetRS functions as a homodimer. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding. As a result of a deletion event, MetRS has a significantly shorter core domain insertion than IleRS, ValRS, and LeuR. Consequently, the MetRS insertion lacks the editing function.
Pssm-ID: 173907 [Multi-domain] Cd Length: 319 Bit Score: 65.63 E-value: 4.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 48 PNVTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGIATQMVVERelkqtEGKSrhdlgreaflervwewKGKF 127
Cdd:cd00814 9 PYVNGVPHLGHLYGTVLADVFARYQRLRGYDVLFVTGTDEHGTKIEQKAEE-----EGVT----------------PQEL 67
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 128 GARIGEQHRYLGASLDWSRERF--TMDEQSSAAVREVFVRLYEEGLMYRAQKLINWCPSC 185
Cdd:cd00814 68 CDKYHEIFKDLFKWLNISFDYFirTTSPRHKEIVQEFFKKLYENGYIYEGEYEGLYCVSC 127
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
50-173 |
3.65e-06 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 51.34 E-value: 3.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 50 VTGSLHIGHALTATIQDILIRWKRMSGFNALWLPGTDHAGiatQMVVE--RELKQTEgksrhdlgrEAFLERVwewKGKF 127
Cdd:PRK12267 15 PNGKPHIGHAYTTIAADALARYKRLQGYDVFFLTGTDEHG---QKIQQaaEKAGKTP---------QEYVDEI---SAGF 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 2318732569 128 garigeqhRYLGASLDWSRERF--TMDEQSSAAVREVFVRLYEEGLMY 173
Cdd:PRK12267 80 --------KELWKKLDISYDKFirTTDERHKKVVQKIFEKLYEQGDIY 119
|
|
| Anticodon_Ia_Leu_BEm |
cd07958 |
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; ... |
718-750 |
2.14e-04 |
|
Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; This domain is found in leucyl tRNA synthetases (LeuRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain. In contrast to other class Ia enzymes, the anticodon is not used as an identity element in LeuRS (with exceptions such as Saccharomyces cerevisiae and some other eukaryotes). No anticodon-binding site can be defined for this family, which includes bacterial and eukaryotic mitochondrial members, as well as LeuRS from the archaeal Halobacteria. LeuRS catalyzes the transfer of leucine to the 3'-end of its tRNA.
Pssm-ID: 153412 [Multi-domain] Cd Length: 117 Bit Score: 42.21 E-value: 2.14e-04
10 20 30
....*....|....*....|....*....|...
gi 2318732569 718 DSARAVLVYSLDRILRLLHPFMPFITEEIWQKL 750
Cdd:cd07958 85 AQHAAVLREALETLVLLLAPFAPHIAEELWEEL 117
|
|
| Anticodon_Ia_Met |
cd07957 |
Anticodon-binding domain of methionyl tRNA synthetases; This domain is found in methionyl tRNA ... |
655-750 |
7.18e-04 |
|
Anticodon-binding domain of methionyl tRNA synthetases; This domain is found in methionyl tRNA synthetases (MetRS), which belong to the class Ia aminoacyl tRNA synthetases. It lies C-terminal to the catalytic core domain, and recognizes and specifically binds to the tRNA anticodon (CAU). MetRS catalyzes the transfer of methionine to the 3'-end of its tRNA.
Pssm-ID: 153411 [Multi-domain] Cd Length: 129 Bit Score: 40.94 E-value: 7.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 655 LTLADRWILSRLQRATTEARASLETYGFAEAASTLYQFlwAEFCDWYI------ELAKgslygtdEQAKDSARAVLvYSL 728
Cdd:cd07957 34 LTEEDEELLEEAEELLEEVAEAMEELEFRKALEEIMEL--ARAANKYIdetapwKLAK-------EEDPERLATVL-YVL 103
|
90 100
....*....|....*....|....*.
gi 2318732569 729 DRILR----LLHPFMPFITEEIWQKL 750
Cdd:cd07957 104 LELLRilaiLLSPFMPETAEKILDQL 129
|
|
| PLN02959 |
PLN02959 |
aminoacyl-tRNA ligase |
15-83 |
2.12e-03 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215518 [Multi-domain] Cd Length: 1084 Bit Score: 42.75 E-value: 2.12e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2318732569 15 EVEARRYAFWLERNYFRAEAPSDKPP----FSMVLPPPNVTGSLHIGHALTATIQDILIRWKRMSGFNALwLP 83
Cdd:PLN02959 17 EIEVAVQKWWEEEKVFEAEAGDEPPKpgekFFGNFPYPYMNGLLHLGHAFSLSKLEFAAAYHRLRGANVL-LP 88
|
|
| metG |
PRK00133 |
methionyl-tRNA synthetase; Reviewed |
45-191 |
2.22e-03 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 234655 [Multi-domain] Cd Length: 673 Bit Score: 42.45 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2318732569 45 LPPPNvtGSLHIGHALTaTIQ-DILIRWKRMSGFNALWLPGTDHAGIATqMVveRELKqtEGKSrhdlgREAFLERVWEw 123
Cdd:PRK00133 10 LPYAN--GPIHLGHLVE-YIQaDIWVRYQRMRGHEVLFVCADDAHGTPI-ML--KAEK--EGIT-----PEELIARYHA- 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2318732569 124 kgkfgarigEQHRYL---GASLD-WSRerfTMDEQSSAAVREVFVRLYEEGLMYRaqKLIN--WCPSCHTALSD 191
Cdd:PRK00133 76 ---------EHKRDFagfGISFDnYGS---THSEENRELAQEIYLKLKENGYIYE--KTIEqlYDPEKGMFLPD 135
|
|
| |
