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Conserved domains on  [gi|1737075326|emb|VAC93207|]
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VgrG protein [Klebsiella aerogenes]

Protein Classification

type VI secretion system Vgr family protein( domain architecture ID 11466136)

type VI secretion system Vgr family protein such as type VI secretion system tip protein VgrG, a core component and effector of Type VI secretion systems (T6SSs) that are involved in the pathogenicity of several Gram-negative bacteria

Gene Ontology:  GO:0033104|GO:0033103
PubMed:  30893029|17873062

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
VgrG COG3501
Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly ...
 18-738 0e+00

Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly [Intracellular trafficking, secretion, and vesicular transport, Mobilome: prophages, transposons, General function prediction only];


:

Pssm-ID: 442724 [Multi-domain]  Cd Length: 743  Bit Score: 720.01  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  18 FWKFSGQEKLSEPFHFQVDLLSQDFAIDRQAMLGKNMTVAVPGQWGQVRYLSGKITAVTVRAEDLGETRYAVyqtTLEPD 97
Cdd:COG3501    23 VLRFSGEEALSRPFEFELELLSEDADLDLDALLGKPATLTLRTADGPERYFHGIVTEFEQLGTDGGLARYRL---TLVPW 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  98 FWPMMRDRNFRIFQQQRVPDIVAKLFSEHNVK-FEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHT 176
Cdd:COG3501   100 LWLLTLRRDSRIFQDKSVPDIVEEVLAEYGLAaFEFRLSGSYPPREYCVQYRESDLDFVSRLLEEEGIYYYFEHEEGGHT 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 177 LVLMDDYQQAESFPGyETIPWHAqPGGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVSPTPGKIDV 256
Cdd:COG3501   180 LVLADDPSAHPPLPG-ATLPYHP-RSGADEEEDSITRWRVRRRVRPGKVTLRDYDFKKPAADLEASASSPRDGDEGDLEV 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 257 YDWPGRF-MEHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMADNAKWLVVGARYDFEENQYASGGG 335
Cdd:COG3501   258 YDYPGRYtADPAEGERLARLRLEALRARAVRVEGESNVRGLAPGRRFTLTGHPRADLNGEYLVTSVTHEGSQNLYSGAGG 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 336 NTAQHRIAFTVIPAATPFVPASRTDWPRTYGPQTARVVGPKGESIWTDKYGRIKVKFHWDRESQGDENSSCWVRVSSAWA 415
Cdd:COG3501   338 EDGGYRNRFTAIPADVPFRPPRRTPKPRIAGPQTATVVGPAGEEIHTDEYGRVKVQFHWDREGKKDENSSCWVRVAQPWA 417

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 416 GQGYGGVQIPRVGDEVVVDFINGEPDRPIVIGRVYNEASMPPWALPAAATQMGFMSRSKDGspDNANALRFEDKPGEEQL 495
Cdd:COG3501   418 GAGWGGHFIPRVGQEVLVAFLDGDPDRPIVTGRVYNGANMPPYTLPANKTRSGIRTRSSPG--GGFNELRFDDKAGQEEI 495

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 496 WLHAERNMDTEVENDETHDVGNNRTKTVGKDETSHIKQNRTRTVDGNESVTVGKDRSKTINGNETTTVEQNRTESVkGNE 575
Cdd:COG3501   496 FLHAEKDMNTLVDNDETITVGNDRTEEVGTDETGTVAGNQGLTVSGDQTVVVGGNQTLVVGGARTLVVGGNLAAVV-GGA 574

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 576 TLSVEQNRDETISGNHTTTVKSDHTATVEGKQSLTVVQDRTRQVQGNESVSVQQNRNVQVTGNQTLGVTGNHDISVTGKQ 655
Cdd:COG3501   575 AATAGGAQATLVAGALLLLAAGGALTTVGGGGTTTGGGAAATAGGGGAGAAAGGAATAAAGAAATSAAGGASSAAAAAGG 654

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 656 TQTITSKQEVTIGAGRTLSITGGDTRFTQGSVTDSATDTVHINVGESGILISNGSVEITAGGSTITINAAGVMVNGKKIE 735
Cdd:COG3501   655 AAGAGGGGLAAAGGGGAAAAGGAGAGGAGGGAGALAAGAAAVAAAAAGGAGGGAAAGGIIGAGGTGIGGGGATAGGGAGA 734


                  ...
gi 1737075326 736 LNA 738
Cdd:COG3501   735 SGG 737
 
Name Accession Description Interval E-value
VgrG COG3501
Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly ...
 18-738 0e+00

Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly [Intracellular trafficking, secretion, and vesicular transport, Mobilome: prophages, transposons, General function prediction only];


Pssm-ID: 442724 [Multi-domain]  Cd Length: 743  Bit Score: 720.01  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  18 FWKFSGQEKLSEPFHFQVDLLSQDFAIDRQAMLGKNMTVAVPGQWGQVRYLSGKITAVTVRAEDLGETRYAVyqtTLEPD 97
Cdd:COG3501    23 VLRFSGEEALSRPFEFELELLSEDADLDLDALLGKPATLTLRTADGPERYFHGIVTEFEQLGTDGGLARYRL---TLVPW 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  98 FWPMMRDRNFRIFQQQRVPDIVAKLFSEHNVK-FEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHT 176
Cdd:COG3501   100 LWLLTLRRDSRIFQDKSVPDIVEEVLAEYGLAaFEFRLSGSYPPREYCVQYRESDLDFVSRLLEEEGIYYYFEHEEGGHT 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 177 LVLMDDYQQAESFPGyETIPWHAqPGGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVSPTPGKIDV 256
Cdd:COG3501   180 LVLADDPSAHPPLPG-ATLPYHP-RSGADEEEDSITRWRVRRRVRPGKVTLRDYDFKKPAADLEASASSPRDGDEGDLEV 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 257 YDWPGRF-MEHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMADNAKWLVVGARYDFEENQYASGGG 335
Cdd:COG3501   258 YDYPGRYtADPAEGERLARLRLEALRARAVRVEGESNVRGLAPGRRFTLTGHPRADLNGEYLVTSVTHEGSQNLYSGAGG 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 336 NTAQHRIAFTVIPAATPFVPASRTDWPRTYGPQTARVVGPKGESIWTDKYGRIKVKFHWDRESQGDENSSCWVRVSSAWA 415
Cdd:COG3501   338 EDGGYRNRFTAIPADVPFRPPRRTPKPRIAGPQTATVVGPAGEEIHTDEYGRVKVQFHWDREGKKDENSSCWVRVAQPWA 417

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 416 GQGYGGVQIPRVGDEVVVDFINGEPDRPIVIGRVYNEASMPPWALPAAATQMGFMSRSKDGspDNANALRFEDKPGEEQL 495
Cdd:COG3501   418 GAGWGGHFIPRVGQEVLVAFLDGDPDRPIVTGRVYNGANMPPYTLPANKTRSGIRTRSSPG--GGFNELRFDDKAGQEEI 495

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 496 WLHAERNMDTEVENDETHDVGNNRTKTVGKDETSHIKQNRTRTVDGNESVTVGKDRSKTINGNETTTVEQNRTESVkGNE 575
Cdd:COG3501   496 FLHAEKDMNTLVDNDETITVGNDRTEEVGTDETGTVAGNQGLTVSGDQTVVVGGNQTLVVGGARTLVVGGNLAAVV-GGA 574

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 576 TLSVEQNRDETISGNHTTTVKSDHTATVEGKQSLTVVQDRTRQVQGNESVSVQQNRNVQVTGNQTLGVTGNHDISVTGKQ 655
Cdd:COG3501   575 AATAGGAQATLVAGALLLLAAGGALTTVGGGGTTTGGGAAATAGGGGAGAAAGGAATAAAGAAATSAAGGASSAAAAAGG 654

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 656 TQTITSKQEVTIGAGRTLSITGGDTRFTQGSVTDSATDTVHINVGESGILISNGSVEITAGGSTITINAAGVMVNGKKIE 735
Cdd:COG3501   655 AAGAGGGGLAAAGGGGAAAAGGAGAGGAGGGAGALAAGAAAVAAAAAGGAGGGAAAGGIIGAGGTGIGGGGATAGGGAGA 734


                  ...
gi 1737075326 736 LNA 738
Cdd:COG3501   735 SGG 737
VI_Rhs_Vgr TIGR03361
type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs ...
 20-520 0e+00

type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.


Pssm-ID: 274542 [Multi-domain]  Cd Length: 513  Bit Score: 623.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  20 KFSGQEKLSEPFHFQVDLLSQDFAIDRQAMLGKNMTVAVPGQWGQVRYLSGKITAVTVRAEDlgeTRYAVYQTTLEPDFW 99
Cdd:TIGR03361  16 SFSGDEALSRLFSFRLELVSADPDIDLEDLLGQPATLTLGRDGGGPRYFHGIVTRFEQGGTG---RRLTRYRLTLVPWLW 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 100 PMMRDRNFRIFQQQRVPDIVAKLFSEHNV-KFEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHTLV 178
Cdd:TIGR03361  93 LLTLRRDSRIFQNKSVPEIITEVLKEHGItDFRFRLSKSYPPREYCVQYRESDLDFVSRLLEEEGIFYYFEHTEDGHTLV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 179 LMDDYQQAESFPGYEtIPWHaQPGGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVS-PTPGKIDVY 257
Cdd:TIGR03361 173 LGDDASAHAPLPGAS-LPYN-PDSGGVADRPVISQWTYRRQVRPGQVALRDYDFKKPAASLEAQASADEQgHQAPDLEHY 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 258 DWPGRFMEHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMADNAKWLVVGARYDFEENQYASGGGNT 337
Cdd:TIGR03361 251 DYPGRFKDQERGKRLARVRLEALRADAKRAEGESNCRRLAPGYLFTLSGHPRAALNREYLVVSVHHHGRQPQVLEESGGS 330

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 338 AQH-RIAFTVIPAATPFVPASRTDWPRTYGPQTARVVGPKGESIWTDKYGRIKVKFHWDRESQGDENSSCWVRVSSAWAG 416
Cdd:TIGR03361 331 GAGyRNSFQCIPATVPFRPPRRTPKPRIDGPQTATVVGPAGEEIYTDEYGRVKVQFHWDRYGKRDEKSSCWVRVAQPWAG 410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 417 QGYGGVQIPRVGDEVVVDFINGEPDRPIVIGRVYNEASMPPWALPAAATQMGFMSRSKDGSpDNANALRFEDKPGEEQLW 496
Cdd:TIGR03361 411 NGWGSVAIPRVGQEVVVDFLEGDPDRPIVTGRVYNAENMPPYSLPANKTQSGFRSRSSKGG-GGFNELRFEDKAGAEEIY 489

                         490       500
                  ....*....|....*....|....
gi 1737075326 497 LHAERNMDTEVENDETHDVGNNRT 520
Cdd:TIGR03361 490 LHAQRDMNTEVENDSTHTVGNNRT 513
Phage_GPD pfam05954
Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D ...
 27-328 4.35e-83

Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D proteins and related bacterial sequences. This family also includes Bacteriophage Mu P proteins and related sequences. This protein forms the phage central baseplate hub.


Pssm-ID: 428689  Cd Length: 302  Bit Score: 266.10  E-value: 4.35e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  27 LSEPFHFQVDLLSQDFAIDRQAMLGKNMTVAVPGQWGQVRYLSGKITAVTVRAEDlgeTRYAVYQTTLEPDFWPMMRDRN 106
Cdd:pfam05954   2 LSRLFEFELTLLSDDPDIDLKALLGQPVTVSIELDGGGPRYFHGIVTEFEQVGSD---GRLTRYRLTLVPWLWLLTLRRD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 107 FRIFQQQRVPDIVAKLFSEH--NVKFEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHTLVLMDDYQ 184
Cdd:pfam05954  79 SRIFQNKTVPDILEAVLGEHgiAVAFRFRLTRSYPPREYCVQYRESDLAFVSRLLEEEGIFYFFEHAEGSHTLVLADDSS 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 185 QAESFPGYETIPWHAQPgGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVSPTPGKIDVYDWPGRFM 264
Cdd:pfam05954 159 ALPPSAGGPSLPYHPPS-GTEAEGDHITRFTARRRLRPGTVTLRDYDYKKPRADLSAVAAAPQGAAGSAYEVYDYPGRYD 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1737075326 265 EHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMAD-NAKWLVVGARYDFEEN 328
Cdd:pfam05954 238 SSAEGERLARLRLEALRARARRFSGESNVRGLAPGRRFTLSGHPRRAAaDREYLITRVEHTGSNN 302
5 PHA02596
baseplate hub subunit and tail lysozyme; Provisional
 486-650 1.02e-16

baseplate hub subunit and tail lysozyme; Provisional


Pssm-ID: 222900 [Multi-domain]  Cd Length: 576  Bit Score: 84.04  E-value: 1.02e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 486 FEDKPGEEQLwlhaeRNMDTEVENDETHDVGNNRTKTVGkDETSHIKQNRTRTVDGNESVTVGKDRSKTINGNETTTVEQ 565
Cdd:PHA02596  404 FDDTPGHERY-----RRVHPTGTYEEIRPDGTRVVKIVG-DDYYIVKQDRNVNVKGNLKVVVEGDAIYYNMGNVLQTIDG 477

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 566 NRTESVKGNETLSVEQNRDETISGNHTTTVKSDHTATVEGKQSLTVVQDRTRQVQGNESVSVQQNRNVQVTGNQTLGVTG 645
Cdd:PHA02596  478 NVTIFVRGNVTKTVEGNGTLYVKGNVTVQVDGNLDATVKGNATTLVEGNQTNTVNGNYKLKVEGNFDMTVGGNWSEQMAG 557


                  ....*
gi 1737075326 646 NHDIS 650
Cdd:PHA02596  558 MSSIA 562
 
Name Accession Description Interval E-value
VgrG COG3501
Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly ...
 18-738 0e+00

Uncharacterized conserved protein VgrG, implicated in type VI secretion and phage assembly [Intracellular trafficking, secretion, and vesicular transport, Mobilome: prophages, transposons, General function prediction only];


Pssm-ID: 442724 [Multi-domain]  Cd Length: 743  Bit Score: 720.01  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  18 FWKFSGQEKLSEPFHFQVDLLSQDFAIDRQAMLGKNMTVAVPGQWGQVRYLSGKITAVTVRAEDLGETRYAVyqtTLEPD 97
Cdd:COG3501    23 VLRFSGEEALSRPFEFELELLSEDADLDLDALLGKPATLTLRTADGPERYFHGIVTEFEQLGTDGGLARYRL---TLVPW 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  98 FWPMMRDRNFRIFQQQRVPDIVAKLFSEHNVK-FEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHT 176
Cdd:COG3501   100 LWLLTLRRDSRIFQDKSVPDIVEEVLAEYGLAaFEFRLSGSYPPREYCVQYRESDLDFVSRLLEEEGIYYYFEHEEGGHT 179

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 177 LVLMDDYQQAESFPGyETIPWHAqPGGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVSPTPGKIDV 256
Cdd:COG3501   180 LVLADDPSAHPPLPG-ATLPYHP-RSGADEEEDSITRWRVRRRVRPGKVTLRDYDFKKPAADLEASASSPRDGDEGDLEV 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 257 YDWPGRF-MEHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMADNAKWLVVGARYDFEENQYASGGG 335
Cdd:COG3501   258 YDYPGRYtADPAEGERLARLRLEALRARAVRVEGESNVRGLAPGRRFTLTGHPRADLNGEYLVTSVTHEGSQNLYSGAGG 337

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 336 NTAQHRIAFTVIPAATPFVPASRTDWPRTYGPQTARVVGPKGESIWTDKYGRIKVKFHWDRESQGDENSSCWVRVSSAWA 415
Cdd:COG3501   338 EDGGYRNRFTAIPADVPFRPPRRTPKPRIAGPQTATVVGPAGEEIHTDEYGRVKVQFHWDREGKKDENSSCWVRVAQPWA 417

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 416 GQGYGGVQIPRVGDEVVVDFINGEPDRPIVIGRVYNEASMPPWALPAAATQMGFMSRSKDGspDNANALRFEDKPGEEQL 495
Cdd:COG3501   418 GAGWGGHFIPRVGQEVLVAFLDGDPDRPIVTGRVYNGANMPPYTLPANKTRSGIRTRSSPG--GGFNELRFDDKAGQEEI 495

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 496 WLHAERNMDTEVENDETHDVGNNRTKTVGKDETSHIKQNRTRTVDGNESVTVGKDRSKTINGNETTTVEQNRTESVkGNE 575
Cdd:COG3501   496 FLHAEKDMNTLVDNDETITVGNDRTEEVGTDETGTVAGNQGLTVSGDQTVVVGGNQTLVVGGARTLVVGGNLAAVV-GGA 574

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 576 TLSVEQNRDETISGNHTTTVKSDHTATVEGKQSLTVVQDRTRQVQGNESVSVQQNRNVQVTGNQTLGVTGNHDISVTGKQ 655
Cdd:COG3501   575 AATAGGAQATLVAGALLLLAAGGALTTVGGGGTTTGGGAAATAGGGGAGAAAGGAATAAAGAAATSAAGGASSAAAAAGG 654

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 656 TQTITSKQEVTIGAGRTLSITGGDTRFTQGSVTDSATDTVHINVGESGILISNGSVEITAGGSTITINAAGVMVNGKKIE 735
Cdd:COG3501   655 AAGAGGGGLAAAGGGGAAAAGGAGAGGAGGGAGALAAGAAAVAAAAAGGAGGGAAAGGIIGAGGTGIGGGGATAGGGAGA 734


                  ...
gi 1737075326 736 LNA 738
Cdd:COG3501   735 SGG 737
VI_Rhs_Vgr TIGR03361
type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs ...
 20-520 0e+00

type VI secretion system Vgr family protein; Members of this protein family belong to the Rhs element Vgr protein family (see TIGR01646), but furthermore all are found in genomes with type VI secretion loci. However, members of this protein family, although recognizably correlated to type VI secretion according the partial phylogenetic profiling algorithm, are often found far the type VI secretion locus.


Pssm-ID: 274542 [Multi-domain]  Cd Length: 513  Bit Score: 623.07  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  20 KFSGQEKLSEPFHFQVDLLSQDFAIDRQAMLGKNMTVAVPGQWGQVRYLSGKITAVTVRAEDlgeTRYAVYQTTLEPDFW 99
Cdd:TIGR03361  16 SFSGDEALSRLFSFRLELVSADPDIDLEDLLGQPATLTLGRDGGGPRYFHGIVTRFEQGGTG---RRLTRYRLTLVPWLW 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 100 PMMRDRNFRIFQQQRVPDIVAKLFSEHNV-KFEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHTLV 178
Cdd:TIGR03361  93 LLTLRRDSRIFQNKSVPEIITEVLKEHGItDFRFRLSKSYPPREYCVQYRESDLDFVSRLLEEEGIFYYFEHTEDGHTLV 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 179 LMDDYQQAESFPGYEtIPWHaQPGGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVS-PTPGKIDVY 257
Cdd:TIGR03361 173 LGDDASAHAPLPGAS-LPYN-PDSGGVADRPVISQWTYRRQVRPGQVALRDYDFKKPAASLEAQASADEQgHQAPDLEHY 250

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 258 DWPGRFMEHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMADNAKWLVVGARYDFEENQYASGGGNT 337
Cdd:TIGR03361 251 DYPGRFKDQERGKRLARVRLEALRADAKRAEGESNCRRLAPGYLFTLSGHPRAALNREYLVVSVHHHGRQPQVLEESGGS 330

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 338 AQH-RIAFTVIPAATPFVPASRTDWPRTYGPQTARVVGPKGESIWTDKYGRIKVKFHWDRESQGDENSSCWVRVSSAWAG 416
Cdd:TIGR03361 331 GAGyRNSFQCIPATVPFRPPRRTPKPRIDGPQTATVVGPAGEEIYTDEYGRVKVQFHWDRYGKRDEKSSCWVRVAQPWAG 410

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 417 QGYGGVQIPRVGDEVVVDFINGEPDRPIVIGRVYNEASMPPWALPAAATQMGFMSRSKDGSpDNANALRFEDKPGEEQLW 496
Cdd:TIGR03361 411 NGWGSVAIPRVGQEVVVDFLEGDPDRPIVTGRVYNAENMPPYSLPANKTQSGFRSRSSKGG-GGFNELRFEDKAGAEEIY 489

                         490       500
                  ....*....|....*....|....
gi 1737075326 497 LHAERNMDTEVENDETHDVGNNRT 520
Cdd:TIGR03361 490 LHAQRDMNTEVENDSTHTVGNNRT 513
vgr_GE TIGR01646
Rhs element Vgr protein; This model represents the Vgr family of proteins, associated with ...
 21-502 2.02e-146

Rhs element Vgr protein; This model represents the Vgr family of proteins, associated with some classes of Rhs elements. This model does not include a large octapeptide repeat region, VGXXXXXX, found in the Vgr of Rhs classes G and E.


Pssm-ID: 273730 [Multi-domain]  Cd Length: 483  Bit Score: 436.91  E-value: 2.02e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  21 FSGQEKLSEPFHFQVDLLSQDFAIDRQAMLGKNMTVA--VPGQWGQVRYLSGKITAVTVRAEDLGETRYavyQTTLEPDF 98
Cdd:TIGR01646   6 FEGNEILSQPFTYELILRSADADLDLAAMLGKDASLSleLPDAASTQRIFTGVIAGFSLGSTANGDARY---SLVLRPWL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  99 WPMMRDRNFRIFQQQRVPDIVAKLFSEHNVK-FEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHTL 177
Cdd:TIGR01646  83 WLLTRRRNNRIFQDTSVPDIIEEILREYGFAdFRFDVAREYPQREYCVQYGETDFDFILRLLEEEGIIYYFEHDPKKHIL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 178 VLMDDYQQAESFPGYETIPWHAqPGGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWmLQTLQNPVSPTPGKIDV- 256
Cdd:TIGR01646 163 VAPDTSGQPQITLGYASLPFEL-PGAMDAREQSIYDWTRAQQVNSASVALVDYDFKNPTAR-LQAQSNISRQQAQVPDLe 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 257 -YDWPGRFMEHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMADNAKWLVVGARYDFEENQYASGGG 335
Cdd:TIGR01646 241 aYDYAGSYLDAQHGELYARLRLEALQSRAAKIQGEGNAAGLAPGQLFVLSGHPRNDQNNGYLIVSAIHSIVQLGWDTGIQ 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 336 NTaQHRIAFTVIPAATPFVPASRTDwPRTYGPQTARVVGPKGESIWTDKYGRIKVKFHWDRESQGDENSSCWVRVSSAWA 415
Cdd:TIGR01646 321 GY-ELPNQFIAIEVDVIWRPAATPL-PKVNGPQIAVVVGAQGEEIHTDKYGRIRVHFHWDRYGQSNDYSSCWIRVAQPWA 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 416 GQGYGGVQIPRVGDEVVVDFINGEPDRPIVIGRVYNEASMPPWALPAAATQMGFMSRSKDGSpdNANALRFEDKPGEEQL 495
Cdd:TIGR01646 399 GKNWGSLAIPRVGQEVIVGFLDGDPDRPIVTGRVYNAANPPPYRLPAHNTQSGFKSRTLRGG--SQNQLRFDDDKGKEQL 476


                  ....*..
gi 1737075326 496 WLHAERN 502
Cdd:TIGR01646 477 QLHAERD 483
Phage_GPD pfam05954
Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D ...
 27-328 4.35e-83

Phage tail baseplate hub (GPD); This family includes a number of phage late expression gene D proteins and related bacterial sequences. This family also includes Bacteriophage Mu P proteins and related sequences. This protein forms the phage central baseplate hub.


Pssm-ID: 428689  Cd Length: 302  Bit Score: 266.10  E-value: 4.35e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  27 LSEPFHFQVDLLSQDFAIDRQAMLGKNMTVAVPGQWGQVRYLSGKITAVTVRAEDlgeTRYAVYQTTLEPDFWPMMRDRN 106
Cdd:pfam05954   2 LSRLFEFELTLLSDDPDIDLKALLGQPVTVSIELDGGGPRYFHGIVTEFEQVGSD---GRLTRYRLTLVPWLWLLTLRRD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 107 FRIFQQQRVPDIVAKLFSEH--NVKFEDKLTRSYRQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHTLVLMDDYQ 184
Cdd:pfam05954  79 SRIFQNKTVPDILEAVLGEHgiAVAFRFRLTRSYPPREYCVQYRESDLAFVSRLLEEEGIFYFFEHAEGSHTLVLADDSS 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 185 QAESFPGYETIPWHAQPgGGAVGEEGISQLMASHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVSPTPGKIDVYDWPGRFM 264
Cdd:pfam05954 159 ALPPSAGGPSLPYHPPS-GTEAEGDHITRFTARRRLRPGTVTLRDYDYKKPRADLSAVAAAPQGAAGSAYEVYDYPGRYD 237

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1737075326 265 EHGDGEAYARIRQQSWQAEQQQTQGIATATGIVPGHTFTLTHAPNMAD-NAKWLVVGARYDFEEN 328
Cdd:pfam05954 238 SSAEGERLARLRLEALRARARRFSGESNVRGLAPGRRFTLSGHPRRAAaDREYLITRVEHTGSNN 302
5 PHA02596
baseplate hub subunit and tail lysozyme; Provisional
 486-650 1.02e-16

baseplate hub subunit and tail lysozyme; Provisional


Pssm-ID: 222900 [Multi-domain]  Cd Length: 576  Bit Score: 84.04  E-value: 1.02e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 486 FEDKPGEEQLwlhaeRNMDTEVENDETHDVGNNRTKTVGkDETSHIKQNRTRTVDGNESVTVGKDRSKTINGNETTTVEQ 565
Cdd:PHA02596  404 FDDTPGHERY-----RRVHPTGTYEEIRPDGTRVVKIVG-DDYYIVKQDRNVNVKGNLKVVVEGDAIYYNMGNVLQTIDG 477

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 566 NRTESVKGNETLSVEQNRDETISGNHTTTVKSDHTATVEGKQSLTVVQDRTRQVQGNESVSVQQNRNVQVTGNQTLGVTG 645
Cdd:PHA02596  478 NVTIFVRGNVTKTVEGNGTLYVKGNVTVQVDGNLDATVKGNATTLVEGNQTNTVNGNYKLKVEGNFDMTVGGNWSEQMAG 557


                  ....*
gi 1737075326 646 NHDIS 650
Cdd:PHA02596  558 MSSIA 562
5 PHA02596
baseplate hub subunit and tail lysozyme; Provisional
 508-678 7.99e-16

baseplate hub subunit and tail lysozyme; Provisional


Pssm-ID: 222900 [Multi-domain]  Cd Length: 576  Bit Score: 81.34  E-value: 7.99e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 508 ENDETHdvGNNRTKTV---GKDETSHIKQNRTRTVDGNESVTVGKDRSKTINGNETTTVEqnrtesvkGNETLSVEQNRD 584
Cdd:PHA02596  403 EFDDTP--GHERYRRVhptGTYEEIRPDGTRVVKIVGDDYYIVKQDRNVNVKGNLKVVVE--------GDAIYYNMGNVL 472

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 585 ETISGNHTTTVKSDHTATVEGKQSLTVVQDRTRQVQGNESVSVQQNRNVQVTGNQT--------LGVTGNHDISVTGKQT 656
Cdd:PHA02596  473 QTIDGNVTIFVRGNVTKTVEGNGTLYVKGNVTVQVDGNLDATVKGNATTLVEGNQTntvngnykLKVEGNFDMTVGGNWS 552

                         170       180
                  ....*....|....*....|..
gi 1737075326 657 QTITSkqeVTIGAGRTLSITGG 678
Cdd:PHA02596  553 EQMAG---MSSIASGTYTIDGS 571
Phage_base_V pfam04717
Type VI secretion system/phage-baseplate injector OB domain; Family of bacterial and phage ...
 382-450 6.52e-14

Type VI secretion system/phage-baseplate injector OB domain; Family of bacterial and phage baseplate assembly proteins responsible for forming the small spike at the end of the tail or bacterial pathogenic needle-shaft. This entry represents the OB fold part of the structure. This structure contains an unusual extra beta hairpin that forms the foundation of the spike protein's beta helix.


Pssm-ID: 428084 [Multi-domain]  Cd Length: 75  Bit Score: 67.22  E-value: 6.52e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1737075326 382 TDKYGRIKVKFHWdresQGDENSSCWVRVSSAWAGQGYGGVQIPRVGDEVVVDFINGEPDRPIVIGRVY 450
Cdd:pfam04717  11 PDKLGRVKVGVPW----LTDEEESGWARWAAPRAGAGRGLWFLPEVGEQVLVLFEGGDPSRPVVLGGLW 75
COG4253 COG4253
Uncharacterized conserved protein, DUF2345 family [Function unknown];
59-727 1.52e-10

Uncharacterized conserved protein, DUF2345 family [Function unknown];


Pssm-ID: 443395 [Multi-domain]  Cd Length: 900  Bit Score: 64.68  E-value: 1.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326  59 PGQWGQVRYLSGKITAVTVRAEDLGETRYAVYQTTLEPDFWPMMRDRNFRIFQQQRVPDIVAKLFSEHNVKFEDKLTRSY 138
Cdd:COG4253   124 PQRRQLSALALALVLAVLSRLQAFSRRALDELLALLLLRLRRRRALLRLRLADAALVRSTVEELLSRRHGDEVAFADDRL 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 139 --RQWDYCVQYAESSFHFISRLLELEGISYLFRHDKDGHTLVLMDDYQQAESFPGYEtIPWHAQPGGGAVGEEGISQLMA 216
Cdd:COG4253   204 teRRASAEAASRADAAALRDLRLALRLARRAATAADDAQTTDDARLTADDSAADAGS-LSGSGGDGGAAGGSLAEATSSL 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 217 SHVVTPGLYSTDDYDFRKPHAWMLQTLQNPVSPTPGKIDVYDWPGRFMEHGDGEAYARIRQQSWQAEQQQTQGIATATGI 296
Cdd:COG4253   283 RVPAASVSLARYQRARRAAAAAAAADARAGGADAAGGVGTGGGRRLAAGLAGAAAEEEEAVGAEARARRRRLLRAARAAI 362

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 297 VPGHTFTLTHAPNMADNAKWLVVGARYDFEENQYASGGGNTAQHRIAFTVIPAATPFVPASRTD--WPRTYGPQTARVVG 374
Cdd:COG4253   363 RLLAAAALALLALGRGALAGRSPAAAAGPGIVGGTDRRARRRATAFVDRAAGPPPRTQRARRPLlpRPRGAGGPPPRVVS 442

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 375 PK-GESIWTDKYGRIKVKFHWDRESQGDENSSCWVRVSSAWAGQGYGGVQIPRVGDEVVVDFINGEPDRPivigrvyneA 453
Cdd:COG4253   443 TRaGDTPSADDDDGGRRVVRDDRRVAWVGGGESWGAGGGAGAGGGVGGGVVPLLGDGDVVIAAEGGGPPA---------P 513

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 454 SMPPWALPAAATQM---GFMSRSKDGSPDNANALRFEDKPGEEQlwLHAERnmdtevendETHDVGNNRTKTVGKdetsH 530
Cdd:COG4253   514 GGGAPAAHSAAHLDhssGALSGGNSRNTGGNGLNLLDDDDDEGQ--QRSAT---------QSGKTQLLLLLLVLL----Q 578

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 531 IKQN---RTRTVDGNESVTVGKDRSKTINGNETTTveqnRTESVKGNETlsveqNRDETIS--GNHTTTVKS------DH 599
Cdd:COG4253   579 QQRRgrgGERRGGFELATDAGGALRAAAGLLLSAT----GQRNAQGTQL-----DMAEALAqlEQALELAKSlsdaaaQA 649

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 600 TA-TVEGKQSLTVVQDRTRQVQGNESVSVQQNRN------VQVTGNQTLGVTGNHDISVTGKQTQTITSKQEVTIGAGRT 672
Cdd:COG4253   650 QAlLLDTAEALKALLDALKGWEAAQGAGLGGTLPalsqpvLLLSAPAGIALTTPQSTQLSAGENLALTAGQDTNIAAGKS 729

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1737075326 673 LSITGGDT--RFTQ----------GSV-----TDS----ATDTVHINVGESGILIS-NGSVEITAGGSTITINAAGV 727
Cdd:COG4253   730 LTVAAGEGisLFAQkggikliaakGKVeiqaqSDAlellAKKDVTITSTAGRITITaKKEILLTAGGAYIRIEGGNI 806
5 PHA02596
baseplate hub subunit and tail lysozyme; Provisional
 546-723 7.04e-05

baseplate hub subunit and tail lysozyme; Provisional


Pssm-ID: 222900 [Multi-domain]  Cd Length: 576  Bit Score: 46.29  E-value: 7.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 546 TVGKDRSKTINgnETTTVEQ-----NRTESVKGNETLSVEQNRDETISGNHTTTVksdhtatvEGKQSLTVVQDRTRQVQ 620
Cdd:PHA02596  407 TPGHERYRRVH--PTGTYEEirpdgTRVVKIVGDDYYIVKQDRNVNVKGNLKVVV--------EGDAIYYNMGNVLQTID 476

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 621 GNESVSVQqnrnvqvtGNQTLGVTGNHDISVTGKQTQTITSKQEVTIGAGRTLSITGGDTRFTQGSVTDSATDTVHINVG 700
Cdd:PHA02596  477 GNVTIFVR--------GNVTKTVEGNGTLYVKGNVTVQVDGNLDATVKGNATTLVEGNQTNTVNGNYKLKVEGNFDMTVG 548

                         170       180       190
                  ....*....|....*....|....*....|
gi 1737075326 701 ESGI-------LISNGSVEITagGSTITIN 723
Cdd:PHA02596  549 GNWSeqmagmsSIASGTYTID--GSRIDIG 576
Gp5_C pfam06715
Gp5 C-terminal repeat (3 copies); This repeat composes the C-terminal part of the ...
 573-596 1.71e-03

Gp5 C-terminal repeat (3 copies); This repeat composes the C-terminal part of the bacteriophage T4 baseplate protein Gp5. This region of the protein forms a needle like projection from the baseplate that is presumed to puncture the bacterial cell membrane. Structurally three copies of the repeated region trimerize to form a beta solenoid type structure. This family also includes repeats from bacterial Vgr proteins.


Pssm-ID: 310962 [Multi-domain]  Cd Length: 24  Bit Score: 36.11  E-value: 1.71e-03
                          10        20
                  ....*....|....*....|....
gi 1737075326 573 GNETLSVEQNRDETISGNHTTTVK 596
Cdd:pfam06715   1 GNETETVGGNRTVTVGGNETETVG 24
DUF6484 pfam20093
Domain of unknown function (DUF6484); This domain of unknown function is found in ...
 427-449 1.73e-03

Domain of unknown function (DUF6484); This domain of unknown function is found in uncharacterized proteins from Proteobacteria. This domain is approximately 80 amino acids in length and exhibits overlaps with pfam04717, which suggests that it has an OB fold and, thus, it belongs to the same clan. Many proteins containing this domain are related to the Type VI secretion system and to Phage-related baseplate proteins.


Pssm-ID: 466287 [Multi-domain]  Cd Length: 61  Bit Score: 37.16  E-value: 1.73e-03
                          10        20
                  ....*....|....*....|...
gi 1737075326 427 VGDEVVVDFINGEPDRPIVIGRV 449
Cdd:pfam20093  39 LGREVALLFEDGDPRRPLIMGLL 61
Gp5_C pfam06715
Gp5 C-terminal repeat (3 copies); This repeat composes the C-terminal part of the ...
 557-576 2.18e-03

Gp5 C-terminal repeat (3 copies); This repeat composes the C-terminal part of the bacteriophage T4 baseplate protein Gp5. This region of the protein forms a needle like projection from the baseplate that is presumed to puncture the bacterial cell membrane. Structurally three copies of the repeated region trimerize to form a beta solenoid type structure. This family also includes repeats from bacterial Vgr proteins.


Pssm-ID: 310962 [Multi-domain]  Cd Length: 24  Bit Score: 36.11  E-value: 2.18e-03
                          10        20
                  ....*....|....*....|
gi 1737075326 557 GNETTTVEQNRTESVKGNET 576
Cdd:pfam06715   1 GNETETVGGNRTVTVGGNET 20
Cthe_2159 pfam14262
Carbohydrate-binding domain-containing protein Cthe_2159; Cthe_2159 from Clostridium ...
 640-738 6.50e-03

Carbohydrate-binding domain-containing protein Cthe_2159; Cthe_2159 from Clostridium thermocellum is the first representative of a novel family of cellulose and/or acid-sugar binding beta-helix proteins that share structural similarities with polysaccharide lyases.


Pssm-ID: 433819 [Multi-domain]  Cd Length: 264  Bit Score: 39.08  E-value: 6.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737075326 640 TLGVTGNHDISVTGKQTQTITSKQEVTIGAGRTLSITG---------GDTRFTQGSVT-DSATDTVHinvGESGILISNG 709
Cdd:pfam14262  70 TLSDGSTYTAIDDDEPDAAIFSKDDLTINGSGTLTVTGnykhgivskDDLKITSGTINvTAVDDGIR---GKDSLVIKGG 146

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1737075326 710 SVEITAGGS--------------------TITINAAG--------VMVNGKKIELNA 738
Cdd:pfam14262 147 TITITAGGDgiksendedatkgyvyitggTFTITAGDdgiqaetdLTINGGTITITT 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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