|
Name |
Accession |
Description |
Interval |
E-value |
| trkA |
PRK09496 |
Trk system potassium transporter TrkA; |
1-456 |
0e+00 |
|
Trk system potassium transporter TrkA;
Pssm-ID: 236541 [Multi-domain] Cd Length: 453 Bit Score: 731.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 1 MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNM 80
Cdd:PRK09496 1 MKIIIVGAGQVGYTLAENLSGENNDVTVIDTDEERLRRLQDRLDVRTVVGNGSSPDVLREAGAEDADLLIAVTDSDETNM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 81 VACQVAYSLFNTPNRIARIRAPDYvRDAEKLFNSEAVPIDHLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKA 160
Cdd:PRK09496 81 VACQIAKSLFGAPTTIARVRNPEY-AEYDKLFSKEALGIDLLISPELLVAREIARLIEYPGALDVEEFADGRVQLVEVKV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 161 YYGGPLVGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG 240
Cdd:PRK09496 160 YEGSPLVGKPLSDLREHFPDIDVRVVAIFRGGRLIIPRGDTVIEAGDEVYFIGAREHIRAVMSEFGRLEKPVKRVMIVGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 241 GNIGAGLAHKLEK-DYSVKLIERNQQRAAELAEKLQHTIVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAK 319
Cdd:PRK09496 240 GNIGYYLAKLLEKeGYSVKLIERDPERAEELAEELPNTLVLHGDGTDQELLEEEGIDEADAFIALTNDDEANILSSLLAK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 320 RMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHgdeSTSRVVGRSI 399
Cdd:PRK09496 320 RLGAKKVIALVNRPAYVDLVEGLGIDIAISPRQATASEILRHVRRGDIVAVHSLRRGAAEAIEAVAH---ETSKVVGKPL 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1737547709 400 DEIKLPPGTIIGAVVRGNDVMIANNNLRIEQGDHVIMFLTDKKFISDVERLFQPSPF 456
Cdd:PRK09496 397 KDLKLPKGVLIGAIVRGGEVIIPTGDTVIEPGDHVIVFVLDKKFVPDVEKLFQVSPF 453
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
137-435 |
3.57e-69 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 221.86 E-value: 3.57e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 137 IEYPGALQVVNFAEGKVSLAVVKAYYGGPLVGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQ 216
Cdd:COG0569 1 LLILLLLLVLLFAMGIEGLVLLDALYGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLGYTLITFGDAVLFGGLLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 217 HIRAVMSELQRLEKPyKRIMLVGGGNIGAGLAHKLEK-DYSVKLIERNQQRAAELAEKlqHTIVFYGDASDQELLAEEHI 295
Cdd:COG0569 81 ALRRRRMERGIKKLK-MHVIIIGAGRVGRSLARELEEeGHDVVVIDKDPERVERLAEE--DVLVIVGDATDEEVLEEAGI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 296 DQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRR 375
Cdd:COG0569 158 EDADAVIAATGDDEANILACLLAKELGVPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELAD 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1737547709 376 GVAEAIEAVAHgdeSTSRVVGRSIDEIKLPP--GTIIGAVVRGNDVMIANNNLRIEQGDHVI 435
Cdd:COG0569 238 GDAEIVEVTVP---EGSPLVGKTLKELDLREryGVTVVAIKRGGEVIIPSGDTVLEAGDELI 296
|
|
| TrkA_N |
pfam02254 |
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ... |
235-350 |
2.28e-26 |
|
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.
Pssm-ID: 426679 [Multi-domain] Cd Length: 115 Bit Score: 102.60 E-value: 2.28e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 235 IMLVGGGNIGAGLAHKLEKDYSVKLIERNQQRAAELAEKLqhTIVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANIMS 314
Cdd:pfam02254 1 IIIIGYGRVGRSLAEELSEGGDVVVIDKDEERVEELREEG--VPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILI 78
|
90 100 110
....*....|....*....|....*....|....*..
gi 1737547709 315 AMLAKRM-GAKKVMVLIQRRAYVDLVQGSVIDIAISP 350
Cdd:pfam02254 79 VLLARELnPDKKIIARANDPEHAELLRRLGADHVISP 115
|
|
| L-AlaDH |
cd05305 |
Alanine dehydrogenase NAD-binding and catalytic domains; Alanine dehydrogenase (L-AlaDH) ... |
2-72 |
5.89e-05 |
|
Alanine dehydrogenase NAD-binding and catalytic domains; Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.
Pssm-ID: 240630 [Multi-domain] Cd Length: 359 Bit Score: 45.09 E-value: 5.89e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1737547709 2 KIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHgSHPRVLREAgADDADMLV-AV 72
Cdd:cd05305 170 KVVILGAGVVGENAARVALGLGAEVTVLDINLERLRYLDDIFGGRVTTLY-SNPANLEEA-LKEADLVIgAV 239
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| trkA |
PRK09496 |
Trk system potassium transporter TrkA; |
1-456 |
0e+00 |
|
Trk system potassium transporter TrkA;
Pssm-ID: 236541 [Multi-domain] Cd Length: 453 Bit Score: 731.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 1 MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNM 80
Cdd:PRK09496 1 MKIIIVGAGQVGYTLAENLSGENNDVTVIDTDEERLRRLQDRLDVRTVVGNGSSPDVLREAGAEDADLLIAVTDSDETNM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 81 VACQVAYSLFNTPNRIARIRAPDYvRDAEKLFNSEAVPIDHLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKA 160
Cdd:PRK09496 81 VACQIAKSLFGAPTTIARVRNPEY-AEYDKLFSKEALGIDLLISPELLVAREIARLIEYPGALDVEEFADGRVQLVEVKV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 161 YYGGPLVGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG 240
Cdd:PRK09496 160 YEGSPLVGKPLSDLREHFPDIDVRVVAIFRGGRLIIPRGDTVIEAGDEVYFIGAREHIRAVMSEFGRLEKPVKRVMIVGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 241 GNIGAGLAHKLEK-DYSVKLIERNQQRAAELAEKLQHTIVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAK 319
Cdd:PRK09496 240 GNIGYYLAKLLEKeGYSVKLIERDPERAEELAEELPNTLVLHGDGTDQELLEEEGIDEADAFIALTNDDEANILSSLLAK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 320 RMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHgdeSTSRVVGRSI 399
Cdd:PRK09496 320 RLGAKKVIALVNRPAYVDLVEGLGIDIAISPRQATASEILRHVRRGDIVAVHSLRRGAAEAIEAVAH---ETSKVVGKPL 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1737547709 400 DEIKLPPGTIIGAVVRGNDVMIANNNLRIEQGDHVIMFLTDKKFISDVERLFQPSPF 456
Cdd:PRK09496 397 KDLKLPKGVLIGAIVRGGEVIIPTGDTVIEPGDHVIVFVLDKKFVPDVEKLFQVSPF 453
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
137-435 |
3.57e-69 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 221.86 E-value: 3.57e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 137 IEYPGALQVVNFAEGKVSLAVVKAYYGGPLVGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQ 216
Cdd:COG0569 1 LLILLLLLVLLFAMGIEGLVLLDALYGLLITLTTVTTLGGGLLDPVTLVAAIFLIGVVIIPLGYTLITFGDAVLFGGLLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 217 HIRAVMSELQRLEKPyKRIMLVGGGNIGAGLAHKLEK-DYSVKLIERNQQRAAELAEKlqHTIVFYGDASDQELLAEEHI 295
Cdd:COG0569 81 ALRRRRMERGIKKLK-MHVIIIGAGRVGRSLARELEEeGHDVVVIDKDPERVERLAEE--DVLVIVGDATDEEVLEEAGI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 296 DQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRR 375
Cdd:COG0569 158 EDADAVIAATGDDEANILACLLAKELGVPRIIARANDPEYADLLERLGADVVISPERLAARRIARLLLRPGVLDVLELAD 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1737547709 376 GVAEAIEAVAHgdeSTSRVVGRSIDEIKLPP--GTIIGAVVRGNDVMIANNNLRIEQGDHVI 435
Cdd:COG0569 238 GDAEIVEVTVP---EGSPLVGKTLKELDLREryGVTVVAIKRGGEVIIPSGDTVLEAGDELI 296
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
1-210 |
1.47e-54 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 184.11 E-value: 1.47e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 1 MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKfDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNM 80
Cdd:COG0569 96 MHVIIIGAGRVGRSLARELEEEGHDVVVIDKDPERVERLAEE-DVLVIVGDATDEEVLEEAGIEDADAVIAATGDDEANI 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 81 VACQVAYSLfNTPNRIARIRAPDYVRDAEKLfnseavPIDHLIAPEQLVIDNIHRLIEYPGALQVVNFAEGKVSLAVVKA 160
Cdd:COG0569 175 LACLLAKEL-GVPRIIARANDPEYADLLERL------GADVVISPERLAARRIARLLLRPGVLDVLELADGDAEIVEVTV 247
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 1737547709 161 YYGGPLVGNALSTMREHMPHiDTRVAAIFRHDRPIRPQGSTIVEAGDEVF 210
Cdd:COG0569 248 PEGSPLVGKTLKELDLRERY-GVTVVAIKRGGEVIIPSGDTVLEAGDELI 296
|
|
| TrkA_N |
pfam02254 |
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ... |
235-350 |
2.28e-26 |
|
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.
Pssm-ID: 426679 [Multi-domain] Cd Length: 115 Bit Score: 102.60 E-value: 2.28e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 235 IMLVGGGNIGAGLAHKLEKDYSVKLIERNQQRAAELAEKLqhTIVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANIMS 314
Cdd:pfam02254 1 IIIIGYGRVGRSLAEELSEGGDVVVIDKDEERVEELREEG--VPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILI 78
|
90 100 110
....*....|....*....|....*....|....*..
gi 1737547709 315 AMLAKRM-GAKKVMVLIQRRAYVDLVQGSVIDIAISP 350
Cdd:pfam02254 79 VLLARELnPDKKIIARANDPEHAELLRRLGADHVISP 115
|
|
| TrkA_N |
pfam02254 |
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include ... |
3-125 |
1.19e-25 |
|
TrkA-N domain; This domain is found in a wide variety of proteins. These proteins include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.
Pssm-ID: 426679 [Multi-domain] Cd Length: 115 Bit Score: 100.68 E-value: 1.19e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 3 IIILGAGQVGGTLAENLVgENNDITLVDTNGDRLRSLQDKFdLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVA 82
Cdd:pfam02254 1 IIIIGYGRVGRSLAEELS-EGGDVVVIDKDEERVEELREEG-VPVVVGDATDEEVLEEAGIEEADAVIAATGDDEANILI 78
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1737547709 83 CQVAYSLFNTPNRIARIRAPDYvrdAEKLfnsEAVPIDHLIAP 125
Cdd:pfam02254 79 VLLARELNPDKKIIARANDPEH---AELL---RRLGADHVISP 115
|
|
| Kch |
COG1226 |
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism]; |
3-111 |
6.60e-11 |
|
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];
Pssm-ID: 440839 [Multi-domain] Cd Length: 279 Bit Score: 62.82 E-value: 6.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 3 IIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQdKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVA 82
Cdd:COG1226 127 VIIAGFGRVGQIVARLLRAEGIPFVVIDLDPERVEELR-RFGIKVYYGDATRPDVLEAAGIERARALVVAIDDPEAALRI 205
|
90 100
....*....|....*....|....*....
gi 1737547709 83 CQVAYSLFNTPNRIARIRapdYVRDAEKL 111
Cdd:COG1226 206 VELARELNPDLKIIARAR---DREHAEEL 231
|
|
| NhaP2 |
COG3263 |
NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains [Energy ... |
392-455 |
8.99e-10 |
|
NhaP-type Na+/H+ and K+/H+ antiporter with C-terminal TrkAC and CorC domains [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 442494 [Multi-domain] Cd Length: 502 Bit Score: 60.51 E-value: 8.99e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1737547709 392 SRVVGRSIDEIKLPPGTIIGAVVRGNDVMIANNNLRIEQGDHVIMFLTDKKfISDVERLFQPSP 455
Cdd:COG3263 424 SPAVGKTLRELRLPEGALVVLIVRDGELLVPRGSTRLQAGDQLLVLAPPED-LEALERLFAAVS 486
|
|
| PRK05326 |
PRK05326 |
potassium/proton antiporter; |
392-455 |
3.05e-08 |
|
potassium/proton antiporter;
Pssm-ID: 235410 [Multi-domain] Cd Length: 562 Bit Score: 55.98 E-value: 3.05e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1737547709 392 SRVVGRSIDEIKLPPGTIIGAVVRGNDVMIANNNLRIEQGDHVIMFLTDKKfISDVERLFQPSP 455
Cdd:PRK05326 425 SWLVGKALRDLRLPRGALIALIIRDGKLLVPTGSTRLKAGDVLLVLGPERD-LPALERLFSQSP 487
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
155-225 |
5.12e-07 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 46.83 E-value: 5.12e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1737547709 155 LAVVKAYYGGPLVGNALS--TMREHMphiDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSEL 225
Cdd:pfam02080 1 LVEVTVPENSPLVGKTLKelNLPERF---GVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
390-451 |
5.65e-07 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 46.83 E-value: 5.65e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1737547709 390 STSRVVGRSIDEIKLP--PGTIIGAVVRGNDVMIANNNLRIEQGDHVImFLTDKKFISDVERLF 451
Cdd:pfam02080 8 ENSPLVGKTLKELNLPerFGVRIVAIRRGGRLIIPSGDTVLEAGDRLL-VIGTPDDLAALRELL 70
|
|
| PRK05326 |
PRK05326 |
potassium/proton antiporter; |
165-300 |
7.91e-07 |
|
potassium/proton antiporter;
Pssm-ID: 235410 [Multi-domain] Cd Length: 562 Bit Score: 51.35 E-value: 7.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 165 PLVGNALstMREHMPHiDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQrlEKPYKRIMLVGGGNIG 244
Cdd:PRK05326 426 WLVGKAL--RDLRLPR-GALIALIIRDGKLLVPTGSTRLKAGDVLLVLGPERDLPALERLFS--QSPPGKLDQRFFGDFI 500
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 245 AGLAHKLEKDYSVKLIERNQQRAAELAEKLQHTIVFYGD----ASDQELLAEEHIDQVDL 300
Cdd:PRK05326 501 LEGDAKLADLALIYGLELDQQTLGELIKQRLGGAPVVGDqvelGGIILTVAEGRVTKVGL 560
|
|
| L-AlaDH |
cd05305 |
Alanine dehydrogenase NAD-binding and catalytic domains; Alanine dehydrogenase (L-AlaDH) ... |
2-72 |
5.89e-05 |
|
Alanine dehydrogenase NAD-binding and catalytic domains; Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.
Pssm-ID: 240630 [Multi-domain] Cd Length: 359 Bit Score: 45.09 E-value: 5.89e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1737547709 2 KIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHgSHPRVLREAgADDADMLV-AV 72
Cdd:cd05305 170 KVVILGAGVVGENAARVALGLGAEVTVLDINLERLRYLDDIFGGRVTTLY-SNPANLEEA-LKEADLVIgAV 239
|
|
| Ald |
COG0686 |
Alanine dehydrogenase (includes sporulation protein SpoVN) [Amino acid transport and ... |
2-72 |
6.33e-05 |
|
Alanine dehydrogenase (includes sporulation protein SpoVN) [Amino acid transport and metabolism]; Alanine dehydrogenase (includes sporulation protein SpoVN) is part of the Pathway/BioSystem: Urea cycle
Pssm-ID: 440450 [Multi-domain] Cd Length: 372 Bit Score: 45.00 E-value: 6.33e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1737547709 2 KIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHgSHPRVLREAgADDADMLV-AV 72
Cdd:COG0686 170 KVVILGGGVVGTNAARMALGLGADVTVLDINLDRLRRLDDIFGGRVTTLY-SNPANIEEA-LKEADLVIgAV 239
|
|
| Kch |
COG1226 |
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism]; |
234-321 |
1.56e-04 |
|
Voltage-gated potassium channel Kch [Inorganic ion transport and metabolism];
Pssm-ID: 440839 [Multi-domain] Cd Length: 279 Bit Score: 43.56 E-value: 1.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 234 RIMLVGGGNIGAGLAHKLE-KDYSVKLIERNQQRAAELAEKLQHtiVFYGDASDQELLAEEHIDQVDLFIAVTNDDEANI 312
Cdd:COG1226 126 HVIIAGFGRVGQIVARLLRaEGIPFVVIDLDPERVEELRRFGIK--VYYGDATRPDVLEAAGIERARALVVAIDDPEAAL 203
|
....*....
gi 1737547709 313 MSAMLAKRM 321
Cdd:COG1226 204 RIVELAREL 212
|
|
| WcaG |
COG0451 |
Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis]; |
2-70 |
8.39e-04 |
|
Nucleoside-diphosphate-sugar epimerase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440220 [Multi-domain] Cd Length: 295 Bit Score: 41.12 E-value: 8.39e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 2 KIIILGA-GQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVVQGHGSHPRVLREAgADDADMLV 70
Cdd:COG0451 1 RILVTGGaGFIGSHLARRLLARGHEVVGLDRSPPGAANLAALPGVEFVRGDLRDPEALAAA-LAGVDAVV 69
|
|
| PRK06522 |
PRK06522 |
2-dehydropantoate 2-reductase; Reviewed |
1-51 |
1.09e-03 |
|
2-dehydropantoate 2-reductase; Reviewed
Pssm-ID: 235821 [Multi-domain] Cd Length: 304 Bit Score: 40.99 E-value: 1.09e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1737547709 1 MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKfDLRVVQGH 51
Cdd:PRK06522 1 MKIAILGAGAIGGLFGAALAQAGHDVTLVARRGAHLDALNEN-GLRLEDGE 50
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
330-451 |
1.67e-03 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 40.88 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1737547709 330 IQRRAYV----DLVQGSVIDI-AISPQQATISALL-----------SHVRKADIVGVSSLRRGVAEAIEAVahGDESTSR 393
Cdd:COG2985 202 LVTRAYRvtnpNLVGKTVAELeALLGTRVVISRIRrggeiivptpdTVLQEGDIVLVVGTREALEAAEALL--GEEVDDS 279
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1737547709 394 ------------------VVGRSIDEIKLPP--GTIIGAVVRGNDVMIANNNLRIEQGDhVIMFLTDKKFISDVERLF 451
Cdd:COG2985 280 elldsdldvrrivvtnkeVAGKTLGELNLRNrfGVVITRVRRGGVELPATPDTVLQLGD-RLTVVGPKEDVERVAKLL 356
|
|
| MviM |
COG0673 |
Predicted dehydrogenase [General function prediction only]; |
234-307 |
3.98e-03 |
|
Predicted dehydrogenase [General function prediction only];
Pssm-ID: 440437 [Multi-domain] Cd Length: 295 Bit Score: 39.14 E-value: 3.98e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1737547709 234 RIMLVGGGNIGAGLAHKLEKDYSVKLI---ERNQQRAAELAEKLQhtIVFYGDAsdQELLAEEHIDQVdlFIAVTND 307
Cdd:COG0673 5 RVGIIGAGGIGRAHAPALAALPGVELVavaDRDPERAEAFAEEYG--VRVYTDY--EELLADPDIDAV--VIATPNH 75
|
|
| NAD_bind_Leu_Phe_Val_DH |
cd01075 |
NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine ... |
1-48 |
8.59e-03 |
|
NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Amino acid dehydrogenase (DH) is a widely distributed family of enzymes that catalyzes the oxidative deamination of an amino acid to its keto acid and ammonia with concomitant reduction of NADP+. For example, leucine DH catalyzes the reversible oxidative deamination of L-leucine and several other straight or branched chain amino acids to the corresponding 2-oxoacid derivative. Amino acid DH -like NAD(P)-binding domains are members of the Rossmann fold superfamily and include glutamate, leucine, and phenylalanine DHs, methylene tetrahydrofolate DH, methylene-tetrahydromethanopterin DH, methylene-tetrahydropholate DH/cyclohydrolase, Shikimate DH-like proteins, malate oxidoreductases, and glutamyl tRNA reductase. Amino acid DHs catalyze the deamination of amino acids to keto acids with NAD(P)+ as a cofactor. The NAD(P)-binding Rossmann fold superfamily includes a wide variety of protein families including NAD(P)- binding domains of alcohol DHs, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate DH, lactate/malate DHs, formate/glycerate DHs, siroheme synthases, 6-phosphogluconate DH, amino acid DHs, repressor rex, NAD-binding potassium channel domain, CoA-binding, and ornithine cyclodeaminase-like domains. These domains have an alpha-beta-alpha configuration. NAD binding involves numerous hydrogen and van der Waals contacts.
Pssm-ID: 133444 Cd Length: 200 Bit Score: 37.57 E-value: 8.59e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1737547709 1 MKIIILGAGQVGGTLAENLVGENNDITLVDTNGDRLRSLQDKFDLRVV 48
Cdd:cd01075 29 KTVAVQGLGKVGYKLAEHLLEEGAKLIVADINEEAVARAAELFGATVV 76
|
|
| |
