|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
13-289 |
5.23e-56 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 182.62 E-value: 5.23e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 13 VMVFLAGC-DYSKPENRDGFFYNTFYVPMDNLIHWLGTSFNNDYGLAIVVLVLVIRIVLLPFMLSNYKNSHMMREKMKVA 91
Cdd:PRK02463 17 MLLTLTGCvGRDKHGNPTGFIWNFLGAPMSYFIDYFANNLGLGFGLAIIIVTIIVRLIILPLGLYQSWKATYQSEKMAYL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 92 KPDIDAIQEKVKRSRTQEEKMAANSEMMEVYKKYDMNPMKSMlGCLPILIQMPIIMGLFFVLKYpsSGGFTEHPyFLWFN 171
Cdd:PRK02463 97 KPVFEPINERLKNATTQEEKMAAQTELMAAQRENGISMLGGI-GCLPLLIQMPFFSALYFAAQY--TKGVSTST-FLGID 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 172 LAKPDIWITIIAGILYFLQAYVSSKSMPAEQRQMGYMMMVISPIMIVWISFSSVSALGLYWSVSAAFLIVQTQVANMYYS 251
Cdd:PRK02463 173 LGSPSLVLTAIIGVLYFFQSWLSMMGVPEEQREQMKAMMYMMPIMMVVFSFSSPAGVGLYWLVGGFFSIIQQLITTYILK 252
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1539269548 252 KLAQREVApmiEAMEKN--KAEASGKG------KNTQVVSKKNKKK 289
Cdd:PRK02463 253 PRLRKQIA---EEFAKNppKAYKSPSGrkdvtpSQNQAIASLPKKK 295
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
29-252 |
3.32e-45 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 151.81 E-value: 3.32e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 29 DGFFYNTFYVPMDNLIHWLGTSFNNdYGLAIVVLVLVIRIVLLPFMLSNYKNShmmrEKMKVAKPDIDAIQEKVKrsrtq 108
Cdd:COG0706 2 DYGWFGFIAKPLFWLLNFLHSLVGN-WGLAIILLTLIVRLLLFPLTVKQYKSM----AKMQELQPELKEIQEKYK----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 109 EEKMAANSEMMEVYKKYDMNPMKsmlGCLPILIQMPIIMGLFFVLkyPSSGGFTEHPyFLWFN-LAKPD---IWITIIAG 184
Cdd:COG0706 72 DDPQKLQQEMMKLYKEEGVNPLG---GCLPMLIQMPIFIALYRVL--RNSIELRHAP-FLGIPdLSAPDpyyIFLPILMG 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1539269548 185 ILYFLQAYVSsksMPAEQRQMGYMMMVISPIMIVWISFSSVSALGLYWSVSAAFLIVQTQVANMYYSK 252
Cdd:COG0706 146 VTMFLQQKLN---PAPAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDK 210
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
72-247 |
4.75e-44 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 147.91 E-value: 4.75e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNSHMMREKMkvakPDIDAIQEKVKrsrtqEEKMAANSEMMEVYKKYDMNPMksmLGCLPILIQMPIIMGLFF 151
Cdd:cd20070 17 PLTLKQYKSMKKMQELQ----PKIKEIQEKYK-----DDKQKLQQEMMKLYKEHGVNPL---GGCLPLLIQMPIFIALYQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 152 VLkypSSGGFTEHPYFLWF--NLAKPDIW--ITIIAGILYFLQAYVSSKSMPAEQRQMGyMMMVISPIMIVWISFSSVSA 227
Cdd:cd20070 85 VL---RNSIELRGAPFLWWilDLSAPDPYyiLPILMGVTMFLQQKLTPTPTDDQAPQQK-MMMYFMPVMFTFIFLSFPSG 160
|
170 180
....*....|....*....|
gi 1539269548 228 LGLYWSVSAAFLIVQTQVAN 247
Cdd:cd20070 161 LVLYWLVSNLFSIIQQLIIN 180
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
72-243 |
4.64e-43 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 145.32 E-value: 4.64e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNSHMMREkmkvAKPDIDAIQEKVKrsrtqEEKMAANSEMMEVYKKYDMNPMksmLGCLPILIQMPIIMGLFF 151
Cdd:TIGR03592 19 PLTLKQYKSMRKMQE----LQPKLKEIQEKYK-----EDPQKLQQEMMKLYKEEGVNPL---GGCLPLLIQMPIFIALYQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 152 VLKYpsSGGFTEHPYFLWFNLAKPDIW--ITIIAGILYFLQAYVSSKSMPAEQRQmgYMMMVISPIMIVWISFSSVSALG 229
Cdd:TIGR03592 87 VLLR--SIELRHAPFLWIIDLSSPDPYyiLPILMGVTMFLQQKLSPKGPPDPAQQ--KMMMYFMPLMFLFFFLSFPAGLV 162
|
170
....*....|....
gi 1539269548 230 LYWSVSAAFLIVQT 243
Cdd:TIGR03592 163 LYWVVSNLFTIIQQ 176
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
72-247 |
9.07e-39 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 134.52 E-value: 9.07e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNShmmrEKMKVAKPDIDAIQEKVKrsrtqEEKMAANSEMMEVYKKYDMNPMksmLGCLPILIQMPIIMGLFF 151
Cdd:pfam02096 18 PLTYKQYKSM----AKMQELQPEMKEIQEKYK-----DDRQKLQQEMMKLYKKEGVNPL---GGCLPMLIQMPIFIALYR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 152 VLKYPSSGGFteHPYFLWF-NLAKPDIWIT-------IIAGILYFLQAYVSSKSMPAEQrQMGYMMMVISPIMIVWISFS 223
Cdd:pfam02096 86 VLRNSIELRH--APFFLWIaDLSAPDPISIlhyyilpILMGVTMFLQQKLTPAPQDQPP-QMKMMMLYFMPLMFLFFFLN 162
|
170 180
....*....|....*....|....
gi 1539269548 224 SVSALGLYWSVSAAFLIVQTQVAN 247
Cdd:pfam02096 163 FPAGLVLYWVVSNLLSIGQQLIIN 186
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
13-289 |
5.23e-56 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 182.62 E-value: 5.23e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 13 VMVFLAGC-DYSKPENRDGFFYNTFYVPMDNLIHWLGTSFNNDYGLAIVVLVLVIRIVLLPFMLSNYKNSHMMREKMKVA 91
Cdd:PRK02463 17 MLLTLTGCvGRDKHGNPTGFIWNFLGAPMSYFIDYFANNLGLGFGLAIIIVTIIVRLIILPLGLYQSWKATYQSEKMAYL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 92 KPDIDAIQEKVKRSRTQEEKMAANSEMMEVYKKYDMNPMKSMlGCLPILIQMPIIMGLFFVLKYpsSGGFTEHPyFLWFN 171
Cdd:PRK02463 97 KPVFEPINERLKNATTQEEKMAAQTELMAAQRENGISMLGGI-GCLPLLIQMPFFSALYFAAQY--TKGVSTST-FLGID 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 172 LAKPDIWITIIAGILYFLQAYVSSKSMPAEQRQMGYMMMVISPIMIVWISFSSVSALGLYWSVSAAFLIVQTQVANMYYS 251
Cdd:PRK02463 173 LGSPSLVLTAIIGVLYFFQSWLSMMGVPEEQREQMKAMMYMMPIMMVVFSFSSPAGVGLYWLVGGFFSIIQQLITTYILK 252
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 1539269548 252 KLAQREVApmiEAMEKN--KAEASGKG------KNTQVVSKKNKKK 289
Cdd:PRK02463 253 PRLRKQIA---EEFAKNppKAYKSPSGrkdvtpSQNQAIASLPKKK 295
|
|
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
12-252 |
1.85e-55 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 179.95 E-value: 1.85e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 12 GVMVFLAGCDYSKP--ENRDGFFYNTFYVPMDNLIHWLGTSFNNDYGLAIVVLVLVIRIVLLPFMLSNYKNSHMMREKMK 89
Cdd:PRK01622 15 LLVLVLSGCSNAAPidAHSDGFFDHYFVYPFSFLIQFVAHHIGGSYGIAIIIVTLIIRSLMIPLAVSQYKSQRGMQEKMA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 90 VAKPDIDAIQEKVKRSRTQEEKMAANSEMMEVYKKYDMNPMKsmLGCLPILIQMPIIMGLFFVLKypSSGGFTEHPyFLW 169
Cdd:PRK01622 95 VMKPELDKIQAKLKVTKDLEKQKEYQKEMMELYKSGNINPLA--MGCLPLLIQMPILSAFYYAIR--RTEEIASHS-FLW 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 170 FNLAKPDIWITIIAGILYFLQAYVS-SKSMPAEQRQMGYMMMVISPIMIVWISFSSVSALGLYWSVSAAFLIVQTQVANM 248
Cdd:PRK01622 170 FNLGHADHILPIIAGLTYFIQMKVSqSNGTSPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITGGLFLMGQTIVLRK 249
|
....
gi 1539269548 249 YYSK 252
Cdd:PRK01622 250 VMER 253
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
29-252 |
3.32e-45 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 151.81 E-value: 3.32e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 29 DGFFYNTFYVPMDNLIHWLGTSFNNdYGLAIVVLVLVIRIVLLPFMLSNYKNShmmrEKMKVAKPDIDAIQEKVKrsrtq 108
Cdd:COG0706 2 DYGWFGFIAKPLFWLLNFLHSLVGN-WGLAIILLTLIVRLLLFPLTVKQYKSM----AKMQELQPELKEIQEKYK----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 109 EEKMAANSEMMEVYKKYDMNPMKsmlGCLPILIQMPIIMGLFFVLkyPSSGGFTEHPyFLWFN-LAKPD---IWITIIAG 184
Cdd:COG0706 72 DDPQKLQQEMMKLYKEEGVNPLG---GCLPMLIQMPIFIALYRVL--RNSIELRHAP-FLGIPdLSAPDpyyIFLPILMG 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1539269548 185 ILYFLQAYVSsksMPAEQRQMGYMMMVISPIMIVWISFSSVSALGLYWSVSAAFLIVQTQVANMYYSK 252
Cdd:COG0706 146 VTMFLQQKLN---PAPAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDK 210
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
72-247 |
4.75e-44 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 147.91 E-value: 4.75e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNSHMMREKMkvakPDIDAIQEKVKrsrtqEEKMAANSEMMEVYKKYDMNPMksmLGCLPILIQMPIIMGLFF 151
Cdd:cd20070 17 PLTLKQYKSMKKMQELQ----PKIKEIQEKYK-----DDKQKLQQEMMKLYKEHGVNPL---GGCLPLLIQMPIFIALYQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 152 VLkypSSGGFTEHPYFLWF--NLAKPDIW--ITIIAGILYFLQAYVSSKSMPAEQRQMGyMMMVISPIMIVWISFSSVSA 227
Cdd:cd20070 85 VL---RNSIELRGAPFLWWilDLSAPDPYyiLPILMGVTMFLQQKLTPTPTDDQAPQQK-MMMYFMPVMFTFIFLSFPSG 160
|
170 180
....*....|....*....|
gi 1539269548 228 LGLYWSVSAAFLIVQTQVAN 247
Cdd:cd20070 161 LVLYWLVSNLFSIIQQLIIN 180
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
72-243 |
4.64e-43 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 145.32 E-value: 4.64e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNSHMMREkmkvAKPDIDAIQEKVKrsrtqEEKMAANSEMMEVYKKYDMNPMksmLGCLPILIQMPIIMGLFF 151
Cdd:TIGR03592 19 PLTLKQYKSMRKMQE----LQPKLKEIQEKYK-----EDPQKLQQEMMKLYKEEGVNPL---GGCLPLLIQMPIFIALYQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 152 VLKYpsSGGFTEHPYFLWFNLAKPDIW--ITIIAGILYFLQAYVSSKSMPAEQRQmgYMMMVISPIMIVWISFSSVSALG 229
Cdd:TIGR03592 87 VLLR--SIELRHAPFLWIIDLSSPDPYyiLPILMGVTMFLQQKLSPKGPPDPAQQ--KMMMYFMPLMFLFFFLSFPAGLV 162
|
170
....*....|....
gi 1539269548 230 LYWSVSAAFLIVQT 243
Cdd:TIGR03592 163 LYWVVSNLFTIIQQ 176
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
72-247 |
9.07e-39 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 134.52 E-value: 9.07e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNShmmrEKMKVAKPDIDAIQEKVKrsrtqEEKMAANSEMMEVYKKYDMNPMksmLGCLPILIQMPIIMGLFF 151
Cdd:pfam02096 18 PLTYKQYKSM----AKMQELQPEMKEIQEKYK-----DDRQKLQQEMMKLYKKEGVNPL---GGCLPMLIQMPIFIALYR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 152 VLKYPSSGGFteHPYFLWF-NLAKPDIWIT-------IIAGILYFLQAYVSSKSMPAEQrQMGYMMMVISPIMIVWISFS 223
Cdd:pfam02096 86 VLRNSIELRH--APFFLWIaDLSAPDPISIlhyyilpILMGVTMFLQQKLTPAPQDQPP-QMKMMMLYFMPLMFLFFFLN 162
|
170 180
....*....|....*....|....
gi 1539269548 224 SVSALGLYWSVSAAFLIVQTQVAN 247
Cdd:pfam02096 163 FPAGLVLYWVVSNLLSIGQQLIIN 186
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
12-243 |
6.73e-30 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 113.32 E-value: 6.73e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 12 GVMVFLAGC-DYSKPENRD--GFFYNTFYVPMDNLIHWLGTSFNNDYGLAIVVLVLVIRIVLLPFMLSNYKNShmmrEKM 88
Cdd:PRK02944 13 ALMAILAGCsEVNQPITPKstGFWNEYFVYPLSQLITYFANLFGSNYGLAIIVVTLLIRLLILPLMIKQTKST----KAM 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 89 KVAKPDIDAIQEKVKrSRTQEEKMAANSEMMEVYKKYDMNPMKsmlGCLPILIQMPIIMGLFFVLKYPSSggFTEHpYFL 168
Cdd:PRK02944 89 QALQPEMQKLKEKYS-SKDQATQQKLQQEMMQLFQKNGVNPLA---GCLPIFIQMPILIAFYHAIMRTSE--ISKH-SFL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1539269548 169 WFNLAKPDIW--ITIIAGILYFLQAYVSSKSMPAEQRQMGyMMMVISPIMIVWISFSSVSALGLYWSVSAAFLIVQT 243
Cdd:PRK02944 162 WFDLGQADPYyiLPIVAGITTFIQQKLMMAGTAGQNPQMA-MMLWLMPIMILIFAINFPAALSLYWVVGNIFMIAQT 237
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
32-247 |
9.73e-27 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 104.05 E-value: 9.73e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 32 FYNTFYVPMDNLIHWLGTSFNNDYGLAIVVLVLVIRIVLLPFMLSNYKNSHMMREkmkvAKPDIDAIQEKVKrsrtqEEK 111
Cdd:PRK00145 8 AFVQFFKFIHGFVSSVISNPNFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNE----IQPEIKKLQAKYK-----NDP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 112 MAANSEMMEVYKKYDMNPMKsmlGCLPILIQMPIIMGLFFVLKYPSSggfTEHPYFLWF-NLAKPDI-WI-TIIAGILYF 188
Cdd:PRK00145 79 QKLQQEMMKLYKEKGVNPLG---GCLPLLIQWPILIALYYVFNNLTG---INGVSFLWIkDLAKPDItWIlPILSGATTY 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 1539269548 189 LQAYVSSKSMPAEQRQMGYMMMVISpIMIVWISFSSVSALGLYWSVSAAFLIVQTQVAN 247
Cdd:PRK00145 153 LSGYLMTKADSSQAGQMKTMNIGMS-IFMGVMSWKFKSALVLYWVIGNLIQIIQTYFIK 210
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
87-252 |
2.63e-23 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 99.18 E-value: 2.63e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 87 KMKVAKPDIDAIQEKVKrsrtqEEKMAANSEMMEVYKKYDMNPMKsmlGCLPILIQMPIIMGLFFVLkyPSSGGFTEHPY 166
Cdd:PRK01318 351 KMKVLQPKMQELKEKYK-----DDPQKMQQEMMELYKKEKVNPLG---GCLPILIQIPIFFALYKVL--LVSIELRHAPF 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 167 FLWFN-LAKPD---IW----ITIIAGILYFLQAYVSsksmPAEQRQMGYMMMVISPIMIVWISFSSVSALGLYWSVSAAF 238
Cdd:PRK01318 421 IGWIHdLSAPDpyfILhiglLPILMGITMFLQQKLN----PTPTDPMQAKIMKFMPLIFTFFFLSFPAGLVLYWIVNNLL 496
|
170
....*....|....
gi 1539269548 239 LIVQTQVANMYYSK 252
Cdd:PRK01318 497 TIIQQYLINRRLEK 510
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
87-245 |
4.71e-23 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 93.74 E-value: 4.71e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 87 KMKVAKPDIDAIQEKVKRSRT---QEEKMAANSEMMEVYKKYDMNPMKSMlgcLPILIQMPIIMGLFFVLK------YPS 157
Cdd:cd20069 32 RMANLQPELQKLQEKLKEARAsgdQLEAAEARKELKELMKKHNVNPLKSL---LLPLVQAPVFISFFFALRkmanlpVPS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 158 --SGGftehpyFLWF-NLAKPD-IWI-TIIAGILYFLQAYVSSKSMPAEQRQMGYM--MMVISPIMIVWISFSSVSALGL 230
Cdd:cd20069 109 fkTGG------LLWFtDLTVPDpYYIlPILTSLTFLATIELGAETGTSGSPQSKTMknVFRGLPVLMIPFTANFPSAVFL 182
|
170
....*....|....*
gi 1539269548 231 YWSVSAAFLIVQTQV 245
Cdd:cd20069 183 YWITSNLFSLAQNLL 197
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
72-245 |
1.49e-19 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 84.14 E-value: 1.49e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNShmmrEKMKVAKPDIDAIQEKVKRSRTQEEKMAANS-EMMEVYKKYDMNPMKsmlGCLPILIQMPIIMGLF 150
Cdd:cd19751 17 PLTLKQQKSM----RKMQVIRPEMEAIREKYKEKASKDKVQQEMQkEMLGLYKKHGVNPMA---GCLPLFIQLPIFMAFY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 151 FVLKypSSGGFTEHPYFLWFNLAKPDIW--ITIIAGILYFLQAyvssKSMPAEQRQMGYM------MMVISPIMIVWISF 222
Cdd:cd19751 90 FAIM--RTEEIRYHTFLWFFDLGQPDYLyiLPFVAGITTYFQF----KMTMSHQQQMQMMqmqmkvMLYVMPVMIIIAGL 163
|
170 180
....*....|....*....|...
gi 1539269548 223 SSVSALGLYWSVSAAFLIVQTQV 245
Cdd:cd19751 164 SFPSALSLYWIISNLFMIIQTYF 186
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
84-247 |
4.20e-16 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 78.30 E-value: 4.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 84 MReKMKVAKPDIDAIQEKVKRsrtqeEKMAANSEMMEVYKKYDMNPMKsmlGCLPILIQMPIIMGLFFVLKypSSGGFTE 163
Cdd:PRK01001 602 MR-RMQKLSPYIQEIQQKYKK-----EPKRAQMEIMALYKTNKVNPIT---GCLPLLIQLPFLIAMFDLLK--SSFLLRG 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 164 HPYFL-WF-NLAKPDI---WIT-------------IIAGILYFLQAYVSS--KSMPA-----EQRQMGYMMMVISPIMIv 218
Cdd:PRK01001 671 ASFIPgWIdNLTAPDVlfsWETpiwfignefhllpILLGVVMFAQQKISSlkRKGPVtdqqrQQEAMGTMMALLFTFMF- 749
|
170 180
....*....|....*....|....*....
gi 1539269548 219 wisFSSVSALGLYWSVSAAFLIVQTQVAN 247
Cdd:PRK01001 750 ---YNFPSGLNIYWLSSMLLGVIQQWVTN 775
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
87-242 |
5.84e-14 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 70.92 E-value: 5.84e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 87 KMKVAKPDIDAIQEKVKRSRtqeEKMaaNSEMMEVYKKYDMNPMKSmlgCLPILIQMPIIMGLFFVLKYPSSGG------ 160
Cdd:PRK01315 70 NMQEIQPKMKKIQEKYKGDR---ERM--SQEMMKLYKETGTNPLSS---CLPLLLQMPIFFALYRVLDSAASRGdgigpi 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 161 -------FTEHPYF-------LWFNLAKPDIWITIIAGIL--------YFLQAYVSSKSMPAE-----QRQMGYMMMVIS 213
Cdd:PRK01315 142 nppllesFRHAHIFgaplaatFLQALNAGNTAVQVVAAVLiilmsasqFITQLQLMTKNMPPEaktgpMAQQQKMLLYLF 221
|
170 180
....*....|....*....|....*....
gi 1539269548 214 PIMIVWISFSSVSALGLYWSVSAAFLIVQ 242
Cdd:PRK01315 222 PLMFLVSGIAFPVGVLFYWLTSNVWTMGQ 250
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
87-289 |
1.76e-12 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 66.24 E-value: 1.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 87 KMKVAKPDIDAIQEKVKRSRTqeeKMAAnsEMMEVYKKYDMNPMksmLGCLPILIQMPIIMGLFFVLKY--PSSGGF--- 161
Cdd:PRK03449 60 KMQELQPQIKALQKKYGNDRQ---KMAL--EMQKLQKEHGFNPI---LGCLPMLAQIPVFLGLFHVLRSfnRTGTGFgql 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 162 -----------------TEHPYFLWFNL--AKPDIWIT-------------------------IIAGILYFLQAYVSSKS 197
Cdd:PRK03449 132 gmsveenrntpnyvfsaEDVQSFLDARLfgAPLSAYITmprsgldafvdftrtniilvgvplmIIAGVATHFNSRASVAR 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 198 MPAEQRQ------MGYMMMVISPIMIVWISFSSVSALGLYWsvsaaflivqtqVANMYYSKLAQREVAPMIEAMEKNKAE 271
Cdd:PRK03449 212 QSAEAAAnpqtamMNKLALWVFPLGVLVGGPFLPLAILLYW------------VSNNIWTFGQQHYVFGKIDKEEEAKKQ 279
|
250 260
....*....|....*....|..
gi 1539269548 272 ASGKGKNTQV----VSKKNKKK 289
Cdd:PRK03449 280 AKAERRAANApkpgAKPKRSKK 301
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
84-154 |
1.38e-07 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 51.91 E-value: 1.38e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1539269548 84 MReKMKVAKPDI----DAIQEKVKR--SRTQEEkmaanseMMEVYKKYDmNPMKsmlGCLPILIQMPIIMGLFFVLK 154
Cdd:PRK02654 53 MR-RMKIAQPVMqkrqAEIQERYKNdpQKQQEE-------MGKLMKEFG-NPLA---GCLPLLVQMPILFALFATLR 117
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
80-243 |
1.04e-06 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 49.24 E-value: 1.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 80 NSHMMREkMKVAKPDIDAIQEKVKRSRTQEEKMAAnsEMMEVYKKYDMNP---MKSMLGCLPILIQMPIIMGLFFVLKYP 156
Cdd:PRK02201 158 NQEKQEE-LQGKKAKIDAKYKDYKKDKQMKQRKQQ--EIQELYKKHNISPfspFVQMFVTLPIFIAVYRVVQSLPSIKVT 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 157 SSGG--FTEHPYFLWFNLAKPDIWITIIAGILYFLQAYV----------SSKSMPAEQRQMGYMMMVISPIMIVWISF-- 222
Cdd:PRK02201 235 TWLGidLSATSWQEIFAGNWIYLPILIIVVPVQALSQLLpqilnkkknkERTLNVKEKEALKKQNKTQNIISIVFIFFgv 314
|
170 180
....*....|....*....|.
gi 1539269548 223 SSVSALGLYWSVSAAFLIVQT 243
Cdd:PRK02201 315 IFAAGVQIYWIIGGIWTILQT 335
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
72-153 |
1.46e-05 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 46.00 E-value: 1.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1539269548 72 PFMLSNYKNSH---MMREKMKV------AKPDIDAIQEKVKRSRtqeekmaansemmEVYKKYDMNPMKsmlGCLPILIQ 142
Cdd:PRK00247 49 PFTWQQYKSGRtaaHIRPKRKAlreeykGKTDEASIRELQQKQK-------------DLNKEYGYNPLA---GCVPALIQ 112
|
90
....*....|.
gi 1539269548 143 MPIIMGLFFVL 153
Cdd:PRK00247 113 IPVFLGLYQVL 123
|
|
| PHA00368 |
PHA00368 |
internal virion protein D |
182-229 |
1.86e-04 |
|
internal virion protein D
Pssm-ID: 222785 [Multi-domain] Cd Length: 1315 Bit Score: 42.85 E-value: 1.86e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 1539269548 182 IAGILYFLQAYVSSKSMPAEQRQmGYMMMVISPIMIVWISFSSVSALG 229
Cdd:PHA00368 1144 LAGGYYVAQAHVKAYGLPEEQRK-EYLKNALDPTMIAYAALSRSSHLG 1190
|
|
| |
