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Conserved domains on  [gi|445930792|ref|WP_000008647|]
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MULTISPECIES: TrbC/VirB2 family protein [Gammaproteobacteria]

Protein Classification

TrbC/VirB2 family protein( domain architecture ID 10522976)

TrbC/VirB2 family protein may function a major pilus subunit; similar to type IV secretion system protein PtlA, which is a component of the type IV secretion system ptl required for secretion of assembled pertussis toxin (PTX) through the outer membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 24-105 3.86e-09

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


:

Pssm-ID: 398559  Cd Length: 98  Bit Score: 49.53  E-value: 3.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445930792   24 KVVMAVAGATVASPAFADGFS-KAETLLEKVKTGLSG-LSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAE 101
Cdd:pfam04956  14 ALALAALLLLLASPAFAQGSGdPVETALQNIVDSLTGpIARVIATIAIIIAGIMLAFGRLSWRTLVYVVIGIVIIFGAST 93


                  ....
gi 445930792  102 VASM 105
Cdd:pfam04956  94 IVST 97
 
Name Accession Description Interval E-value
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 24-105 3.86e-09

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


Pssm-ID: 398559  Cd Length: 98  Bit Score: 49.53  E-value: 3.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445930792   24 KVVMAVAGATVASPAFADGFS-KAETLLEKVKTGLSG-LSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAE 101
Cdd:pfam04956  14 ALALAALLLLLASPAFAQGSGdPVETALQNIVDSLTGpIARVIATIAIIIAGIMLAFGRLSWRTLVYVVIGIVIIFGAST 93


                  ....
gi 445930792  102 VASM 105
Cdd:pfam04956  94 IVST 97
 
Name Accession Description Interval E-value
TrbC pfam04956
TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein ...
 24-105 3.86e-09

TrbC/VIRB2 pilin; TrbC is a pilin found in bacterial type IV secretion systems. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains VIRB2 type IV secretion proteins. This alignment contains two predicted transmembrane helices.


Pssm-ID: 398559  Cd Length: 98  Bit Score: 49.53  E-value: 3.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445930792   24 KVVMAVAGATVASPAFADGFS-KAETLLEKVKTGLSG-LSLVTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAE 101
Cdd:pfam04956  14 ALALAALLLLLASPAFAQGSGdPVETALQNIVDSLTGpIARVIATIAIIIAGIMLAFGRLSWRTLVYVVIGIVIIFGAST 93


                  ....
gi 445930792  102 VASM 105
Cdd:pfam04956  94 IVST 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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