NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|445936181|ref|WP_000014036|]
View 

MULTISPECIES: Re/Si-specific NAD(P)(+) transhydrogenase subunit beta [Enterobacteriaceae]

Protein Classification

NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta( domain architecture ID 10013240)

NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta is part of a tetrameric membrane-bound proton pump (composed of two alpha and two beta subunits) that catalyzes the reversible transfer of a hydride ion equivalent between NAD and NADP

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
pntB PRK09444
Re/Si-specific NAD(P)(+) transhydrogenase subunit beta;
1-462 0e+00

Re/Si-specific NAD(P)(+) transhydrogenase subunit beta;


:

Pssm-ID: 236520  Cd Length: 462  Bit Score: 997.69  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEM 80
Cdd:PRK09444   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWIIIAMVIGGAIGIRLAKKVEM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  81 TEMPELVAILHSFVGLAAVLVGFNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR 160
Cdd:PRK09444  81 TEMPELVAILHSFVGLAAVLVGFNSYLDHDAGMAPVLVNIHLTEVFLGIFIGAVTFTGSIVAFGKLRGKISSKPLMLPHR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 161 HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240
Cdd:PRK09444 161 HKLNLAALVVSFLLLIVFVRTDSVGLQVFALLLMTLIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVA 320
Cdd:PRK09444 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDEEVGEHRETTAEEVAEMLKNSHSVIITPGYGMAVA 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQD 400
Cdd:PRK09444 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQE 400

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445936181 401 DPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL 462
Cdd:PRK09444 401 DPNSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTQMLFGDAKASVDAILKAL 462
 
Name Accession Description Interval E-value
pntB PRK09444
Re/Si-specific NAD(P)(+) transhydrogenase subunit beta;
1-462 0e+00

Re/Si-specific NAD(P)(+) transhydrogenase subunit beta;


Pssm-ID: 236520  Cd Length: 462  Bit Score: 997.69  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEM 80
Cdd:PRK09444   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWIIIAMVIGGAIGIRLAKKVEM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  81 TEMPELVAILHSFVGLAAVLVGFNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR 160
Cdd:PRK09444  81 TEMPELVAILHSFVGLAAVLVGFNSYLDHDAGMAPVLVNIHLTEVFLGIFIGAVTFTGSIVAFGKLRGKISSKPLMLPHR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 161 HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240
Cdd:PRK09444 161 HKLNLAALVVSFLLLIVFVRTDSVGLQVFALLLMTLIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVA 320
Cdd:PRK09444 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDEEVGEHRETTAEEVAEMLKNSHSVIITPGYGMAVA 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQD 400
Cdd:PRK09444 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQE 400

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445936181 401 DPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL 462
Cdd:PRK09444 401 DPNSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTQMLFGDAKASVDAILKAL 462
PntB COG1282
NAD/NADP transhydrogenase beta subunit [Energy production and conversion];
1-462 0e+00

NAD/NADP transhydrogenase beta subunit [Energy production and conversion];


Pssm-ID: 440893  Cd Length: 458  Bit Score: 806.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEM 80
Cdd:COG1282    1 MSNTLITLAYLVAAVLFILGLKGLSSPETARRGNLLGAVGMLIAVVATLLLPGIVNYGLILAAIAIGGAIGAVLARKVEM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  81 TEMPELVAILHSFVGLAAVLVGFNSYLHHDAGMAPILVnIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR 160
Cdd:COG1282   81 TAMPQLVALFNGFGGLAAALVAAAELLEPGALAGALPA-IHLIEIVLGVLIGAVTFTGSLIAFGKLQGLISGKPITFPGQ 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 161 HKMNLAALVVSFLLLIVFVRTDSvglQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240
Cdd:COG1282  160 HLLNLLLLLAIVALGVLFVVSPG---SLLLLLLLTVLALLLGVLLVLPIGGADMPVVISLLNSYSGLAAAAAGFVLGNDL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVA 320
Cdd:COG1282  237 LIIAGALVGASGAILTYIMCKAMNRSLINVLFGGFGGGGAAAAGAAEQGEVKEISAEDAAILLAYASSVIIVPGYGMAVA 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQD 400
Cdd:COG1282  317 QAQHAVRELADLLEERGVEVKFAIHPVAGRMPGHMNVLLAEANVPYDQLLEMDEINPEFAQTDVALVIGANDVVNPAART 396

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445936181 401 DPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL 462
Cdd:COG1282  397 DPGSPIYGMPILEVDKAKTVIVIKRSMGPGYAGVENPLFYKDNTRMLFGDAKKSVEELVKAL 458
PNTB pfam02233
NAD(P) transhydrogenase beta subunit; This family corresponds to the beta subunit of NADP ...
 8-461 0e+00

NAD(P) transhydrogenase beta subunit; This family corresponds to the beta subunit of NADP transhydrogenase in prokaryotes, and either the protein N- or C terminal in eukaryotes. The domain is often found in conjunction with pfam01262. Pyridine nucleotide transhydrogenase catalyzes the reduction of NAD+ to NADPH. A complete loss of activity occurs upon mutation of Gly314 in E. coli.


Pssm-ID: 460502  Cd Length: 454  Bit Score: 758.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181    8 AAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIAT---IFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMP 84
Cdd:pfam02233   1 AAYLVAAVLFILGLKGLSSPKTARRGNLLGAIGMALAIVATlllGALADSLPYGLILIAIAIGGVIGLYIARRVKMTAMP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181   85 ELVAILHSFVGLAAVLVGFNSYLHHDAGMAPIlVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNRHKMN 164
Cdd:pfam02233  81 QLVALFHSLGGLAAVLVAIAEYLAPEAFGAGI-SAFHLVEIVLGVLIGAVTFTGSLIAFGKLQGLLSSKPLTLPGRHLLN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  165 LAALVVSFLLLIVFVRTDSVglqvLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVT 244
Cdd:pfam02233 160 LLLLLAIVVLGVLFVAAPSS----PGLWLLTALALLLGVLLVLPIGGADMPVVISLLNSYSGWAAAAAGFVLGNPLLIIA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  245 GALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEV--GEHREITAEETAELLKNSHSVIITPGYGMAVAQA 322
Cdd:pfam02233 236 GALVGASGAILTYIMCKAMNRSLTNVLFGGFGAAASAGAAGAAAadGEVKEISAEDAAELLAYASSVIIVPGYGMAVAQA 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  323 QYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQDDP 402
Cdd:pfam02233 316 QHAVAELADLLEERGVEVRFAIHPVAGRMPGHMNVLLAEADVPYDIVLEMDEINDDFADTDVALVIGANDVVNPAARTDP 395

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 445936181  403 KSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKA 461
Cdd:pfam02233 396 GSPIYGMPILEVWKAKTVIVIKRSMGPGYAGVDNPLFYKDNTRMLFGDAKKSLEELVKA 454
 
Name Accession Description Interval E-value
pntB PRK09444
Re/Si-specific NAD(P)(+) transhydrogenase subunit beta;
1-462 0e+00

Re/Si-specific NAD(P)(+) transhydrogenase subunit beta;


Pssm-ID: 236520  Cd Length: 462  Bit Score: 997.69  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEM 80
Cdd:PRK09444   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWIIIAMVIGGAIGIRLAKKVEM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  81 TEMPELVAILHSFVGLAAVLVGFNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR 160
Cdd:PRK09444  81 TEMPELVAILHSFVGLAAVLVGFNSYLDHDAGMAPVLVNIHLTEVFLGIFIGAVTFTGSIVAFGKLRGKISSKPLMLPHR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 161 HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240
Cdd:PRK09444 161 HKLNLAALVVSFLLLIVFVRTDSVGLQVFALLLMTLIALAFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVA 320
Cdd:PRK09444 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDEEVGEHRETTAEEVAEMLKNSHSVIITPGYGMAVA 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQD 400
Cdd:PRK09444 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQE 400

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445936181 401 DPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL 462
Cdd:PRK09444 401 DPNSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTQMLFGDAKASVDAILKAL 462
PntB COG1282
NAD/NADP transhydrogenase beta subunit [Energy production and conversion];
1-462 0e+00

NAD/NADP transhydrogenase beta subunit [Energy production and conversion];


Pssm-ID: 440893  Cd Length: 458  Bit Score: 806.22  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181   1 MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEM 80
Cdd:COG1282    1 MSNTLITLAYLVAAVLFILGLKGLSSPETARRGNLLGAVGMLIAVVATLLLPGIVNYGLILAAIAIGGAIGAVLARKVEM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  81 TEMPELVAILHSFVGLAAVLVGFNSYLHHDAGMAPILVnIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR 160
Cdd:COG1282   81 TAMPQLVALFNGFGGLAAALVAAAELLEPGALAGALPA-IHLIEIVLGVLIGAVTFTGSLIAFGKLQGLISGKPITFPGQ 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 161 HKMNLAALVVSFLLLIVFVRTDSvglQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL 240
Cdd:COG1282  160 HLLNLLLLLAIVALGVLFVVSPG---SLLLLLLLTVLALLLGVLLVLPIGGADMPVVISLLNSYSGLAAAAAGFVLGNDL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 241 LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVA 320
Cdd:COG1282  237 LIIAGALVGASGAILTYIMCKAMNRSLINVLFGGFGGGGAAAAGAAEQGEVKEISAEDAAILLAYASSVIIVPGYGMAVA 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181 321 QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQD 400
Cdd:COG1282  317 QAQHAVRELADLLEERGVEVKFAIHPVAGRMPGHMNVLLAEANVPYDQLLEMDEINPEFAQTDVALVIGANDVVNPAART 396

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445936181 401 DPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL 462
Cdd:COG1282  397 DPGSPIYGMPILEVDKAKTVIVIKRSMGPGYAGVENPLFYKDNTRMLFGDAKKSVEELVKAL 458
PNTB pfam02233
NAD(P) transhydrogenase beta subunit; This family corresponds to the beta subunit of NADP ...
 8-461 0e+00

NAD(P) transhydrogenase beta subunit; This family corresponds to the beta subunit of NADP transhydrogenase in prokaryotes, and either the protein N- or C terminal in eukaryotes. The domain is often found in conjunction with pfam01262. Pyridine nucleotide transhydrogenase catalyzes the reduction of NAD+ to NADPH. A complete loss of activity occurs upon mutation of Gly314 in E. coli.


Pssm-ID: 460502  Cd Length: 454  Bit Score: 758.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181    8 AAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIAT---IFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMP 84
Cdd:pfam02233   1 AAYLVAAVLFILGLKGLSSPKTARRGNLLGAIGMALAIVATlllGALADSLPYGLILIAIAIGGVIGLYIARRVKMTAMP 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181   85 ELVAILHSFVGLAAVLVGFNSYLHHDAGMAPIlVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNRHKMN 164
Cdd:pfam02233  81 QLVALFHSLGGLAAVLVAIAEYLAPEAFGAGI-SAFHLVEIVLGVLIGAVTFTGSLIAFGKLQGLLSSKPLTLPGRHLLN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  165 LAALVVSFLLLIVFVRTDSVglqvLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVT 244
Cdd:pfam02233 160 LLLLLAIVVLGVLFVAAPSS----PGLWLLTALALLLGVLLVLPIGGADMPVVISLLNSYSGWAAAAAGFVLGNPLLIIA 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  245 GALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEV--GEHREITAEETAELLKNSHSVIITPGYGMAVAQA 322
Cdd:pfam02233 236 GALVGASGAILTYIMCKAMNRSLTNVLFGGFGAAASAGAAGAAAadGEVKEISAEDAAELLAYASSVIIVPGYGMAVAQA 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445936181  323 QYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQDDP 402
Cdd:pfam02233 316 QHAVAELADLLEERGVEVRFAIHPVAGRMPGHMNVLLAEADVPYDIVLEMDEINDDFADTDVALVIGANDVVNPAARTDP 395

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 445936181  403 KSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKA 461
Cdd:pfam02233 396 GSPIYGMPILEVWKAKTVIVIKRSMGPGYAGVDNPLFYKDNTRMLFGDAKKSLEELVKA 454
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH