|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15001 |
PRK15001 |
23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG; |
1-378 |
0e+00 |
|
23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG;
Pssm-ID: 184963 [Multi-domain] Cd Length: 378 Bit Score: 826.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 1 MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELAT 80
Cdd:PRK15001 1 MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELAT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 81 RENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG 160
Cdd:PRK15001 81 RENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 161 PTTTTLAWKKARLINCTFNEPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNG 240
Cdd:PRK15001 161 PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 241 VIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAW 320
Cdd:PRK15001 241 VIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAW 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 445940840 321 EMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR 378
Cdd:PRK15001 321 EMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR 378
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
180-373 |
1.63e-91 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 272.83 E-value: 1.63e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 180 EPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVD 259
Cdd:COG2813 1 APAASDWPRTITVRLAGRDLTFVTLPGVFSRDRLDIGTRLLLEHLPEPLGGRVLDLGCGYGVIGLALAKRNPEARVTLVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 260 ESPMAVASSRLNVETNmpeALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIV 339
Cdd:COG2813 81 VNARAVELARANAAAN---GLENVEVLWSDGLSGVPDGSFDLILSNPPFHAGRAVDKEVAHALIADAARHLRPGGELWLV 157
|
170 180 190
....*....|....*....|....*....|....
gi 445940840 340 ANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVK 373
Cdd:COG2813 158 ANRHLPYERKLEELFGNVEVLARNKGFKVLRAVK 191
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
198-370 |
3.49e-80 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 242.88 E-value: 3.49e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 198 DWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNmp 277
Cdd:pfam05175 1 ELTFKTLPGVFSHGRLDIGSRLLLEHLPKDLSGKVLDLGCGAGVLGAALAKESPDAELTMVDINARALESARENLAAN-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 278 eALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNC 357
Cdd:pfam05175 79 -GLENGEVVASDVYSGVEDGKFDLIISNPPFHAGLATTYNVAQRFIADAKRHLRPGGELWIVANRFLGYPPLLEELFGNV 157
|
170
....*....|...
gi 445940840 358 TTIATNNKFVVLK 370
Cdd:pfam05175 158 EVVAKTNGFKVLK 170
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
232-339 |
1.21e-07 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 49.35 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLdKNPQAKVVFVDESPMAVASSRLNVETNmpeALDRCEFMINNALSGV--EPFRFNAVLCNPPFH 309
Cdd:cd02440 2 VLDLGCGTGALALALA-SGPGARVTGVDISPVALELARKAAAAL---LADNVEVLKGDAEELPpeADESFDVIISDPPLH 77
|
90 100 110
....*....|....*....|....*....|
gi 445940840 310 QQHALtdnvAWEMFHHARRCLKINGELYIV 339
Cdd:cd02440 78 HLVED----LARFLEEARRLLKPGGVLVLT 103
|
|
| hemK_fam |
TIGR00536 |
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme ... |
231-308 |
2.83e-07 |
|
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme biosynthesis and originally suggested to be protoporphyrinogen oxidase. Functional analysis of the nearest homolog in Saccharomyces cerevisiae, YNL063w, finds it is not protoporphyrinogen oxidase and sequence analysis suggests that HemK homologs have S-adenosyl-methionine-dependent methyltransferase activity (Medline 99237242). Homologs are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both E. coli and H. influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain. [Protein fate, Protein modification and repair]
Pssm-ID: 273125 [Multi-domain] Cd Length: 284 Bit Score: 51.59 E-value: 2.83e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 445940840 231 EIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEalDRCEFMINNALSGVEPFRFNAVLCNPPF 308
Cdd:TIGR00536 117 HILDLGTGSGCIALALAYEFPNAEVIAVDISPDALAVAEENAEKNQLE--HRVEFIQSNLFEPLAGQKIDIIVSNPPY 192
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15001 |
PRK15001 |
23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG; |
1-378 |
0e+00 |
|
23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG;
Pssm-ID: 184963 [Multi-domain] Cd Length: 378 Bit Score: 826.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 1 MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELAT 80
Cdd:PRK15001 1 MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELAT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 81 RENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG 160
Cdd:PRK15001 81 RENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 161 PTTTTLAWKKARLINCTFNEPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNG 240
Cdd:PRK15001 161 PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 241 VIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAW 320
Cdd:PRK15001 241 VIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAW 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 445940840 321 EMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR 378
Cdd:PRK15001 321 EMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR 378
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
180-373 |
1.63e-91 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 272.83 E-value: 1.63e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 180 EPQLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVD 259
Cdd:COG2813 1 APAASDWPRTITVRLAGRDLTFVTLPGVFSRDRLDIGTRLLLEHLPEPLGGRVLDLGCGYGVIGLALAKRNPEARVTLVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 260 ESPMAVASSRLNVETNmpeALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIV 339
Cdd:COG2813 81 VNARAVELARANAAAN---GLENVEVLWSDGLSGVPDGSFDLILSNPPFHAGRAVDKEVAHALIADAARHLRPGGELWLV 157
|
170 180 190
....*....|....*....|....*....|....
gi 445940840 340 ANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVK 373
Cdd:COG2813 158 ANRHLPYERKLEELFGNVEVLARNKGFKVLRAVK 191
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
198-370 |
3.49e-80 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 242.88 E-value: 3.49e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 198 DWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNmp 277
Cdd:pfam05175 1 ELTFKTLPGVFSHGRLDIGSRLLLEHLPKDLSGKVLDLGCGAGVLGAALAKESPDAELTMVDINARALESARENLAAN-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 278 eALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNC 357
Cdd:pfam05175 79 -GLENGEVVASDVYSGVEDGKFDLIISNPPFHAGLATTYNVAQRFIADAKRHLRPGGELWIVANRFLGYPPLLEELFGNV 157
|
170
....*....|...
gi 445940840 358 TTIATNNKFVVLK 370
Cdd:pfam05175 158 EVVAKTNGFKVLK 170
|
|
| rsmC |
PRK09489 |
16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC; |
198-377 |
3.71e-30 |
|
16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC;
Pssm-ID: 181902 [Multi-domain] Cd Length: 342 Bit Score: 118.12 E-value: 3.71e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 198 DWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMP 277
Cdd:PRK09489 166 GLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSAVLARHSPKIRLTLSDVSAAALESSRATLAANGL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 278 EAldrcEFMINNALSGVEPfRFNAVLCNPPFHQ--QHALTdnVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFG 355
Cdd:PRK09489 246 EG----EVFASNVFSDIKG-RFDMIISNPPFHDgiQTSLD--AAQTLIRGAVRHLNSGGELRIVANAFLPYPDLLDETFG 318
|
170 180
....*....|....*....|..
gi 445940840 356 NCTTIATNNKFVVLKAVkLGRR 377
Cdd:PRK09489 319 SHEVLAQTGRFKVYRAI-MTRQ 339
|
|
| PRK09328 |
PRK09328 |
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional |
232-338 |
1.89e-13 |
|
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
Pssm-ID: 236467 [Multi-domain] Cd Length: 275 Bit Score: 69.81 E-value: 1.89e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNmpeALDRCEFMINNALSGVEPFRFNAVLCNPP---F 308
Cdd:PRK09328 112 VLDLGTGSGAIALALAKERPDAEVTAVDISPEALAVARRNAKHG---LGARVEFLQGDWFEPLPGGRFDLIVSNPPyipE 188
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 445940840 309 HQQHALTDNVA-WE-----------------MFHHARRCLKINGELYI 338
Cdd:PRK09328 189 ADIHLLQPEVRdHEphlalfggedgldfyrrIIEQAPRYLKPGGWLLL 236
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
232-352 |
3.79e-13 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 68.25 E-value: 3.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEalDRCEFM---INNALSGVEPFRFNAVLCNPPF 308
Cdd:COG4123 41 VLDLGTGTGVIALMLAQRSPGARITGVEIQPEAAELARRNVALNGLE--DRITVIhgdLKEFAAELPPGSFDLVVSNPPY 118
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 445940840 309 HQQ---------------HALTDNVAwEMFHHARRCLKINGELYIV--ANRHLDYFHKLKK 352
Cdd:COG4123 119 FKAgsgrkspdearaiarHEDALTLE-DLIRAAARLLKPGGRFALIhpAERLAEILAALRK 178
|
|
| HemK |
COG2890 |
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ... |
222-307 |
5.04e-12 |
|
Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442135 [Multi-domain] Cd Length: 282 Bit Score: 65.56 E-value: 5.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 222 QHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNmpEALDRCEFMINNALSGVEPF-RFN 300
Cdd:COG2890 106 ALLPAGAPPRVLDLGTGSGAIALALAKERPDARVTAVDISPDALAVARRNAERL--GLEDRVRFLQGDLFEPLPGDgRFD 183
|
....*..
gi 445940840 301 AVLCNPP 307
Cdd:COG2890 184 LIVSNPP 190
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
232-334 |
1.91e-09 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 54.11 E-value: 1.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLDKnPQAKVVFVDESPMAVASSRLNVETNMPealdRCEFMINNALS-GVEPFRFNAVLCNPPFhq 310
Cdd:pfam13649 1 VLDLGCGTGRLTLALARR-GGARVTGVDLSPEMLERARERAAEAGL----NVEFVQGDAEDlPFPDGSFDLVVSSGVL-- 73
|
90 100
....*....|....*....|....
gi 445940840 311 qHALTDNVAWEMFHHARRCLKING 334
Cdd:pfam13649 74 -HHLPDPDLEAALREIARVLKPGG 96
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
232-339 |
1.40e-08 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 51.75 E-value: 1.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRlnvetnmpEALDRCEFMINNALSGVEPFRFNAVLCNPPFH-- 309
Cdd:COG4106 5 VLDLGCGTGRLTALLAERFPGARVTGVDLSPEMLARAR--------ARLPNVRFVVADLRDLDPPEPFDLVVSNAALHwl 76
|
90 100 110
....*....|....*....|....*....|
gi 445940840 310 QQHAltdnvawEMFHHARRCLKINGELYIV 339
Cdd:COG4106 77 PDHA-------ALLARLAAALAPGGVLAVQ 99
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
233-336 |
2.67e-08 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 51.21 E-value: 2.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 233 VDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFmINNALSGVEPFRFNAVLCNppfHQQH 312
Cdd:pfam08242 1 LEIGCGTGTLLRALLEALPGLEYTGLDISPAALEAARERLAALGLLNAVRVEL-FQLDLGELDPGSFDVVVAS---NVLH 76
|
90 100
....*....|....*....|....
gi 445940840 313 ALTDnvAWEMFHHARRCLKINGEL 336
Cdd:pfam08242 77 HLAD--PRAVLRNIRRLLKPGGVL 98
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
232-339 |
1.21e-07 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 49.35 E-value: 1.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLdKNPQAKVVFVDESPMAVASSRLNVETNmpeALDRCEFMINNALSGV--EPFRFNAVLCNPPFH 309
Cdd:cd02440 2 VLDLGCGTGALALALA-SGPGARVTGVDISPVALELARKAAAAL---LADNVEVLKGDAEELPpeADESFDVIISDPPLH 77
|
90 100 110
....*....|....*....|....*....|
gi 445940840 310 QQHALtdnvAWEMFHHARRCLKINGELYIV 339
Cdd:cd02440 78 HLVED----LARFLEEARRLLKPGGVLVLT 103
|
|
| hemK_fam |
TIGR00536 |
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme ... |
231-308 |
2.83e-07 |
|
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme biosynthesis and originally suggested to be protoporphyrinogen oxidase. Functional analysis of the nearest homolog in Saccharomyces cerevisiae, YNL063w, finds it is not protoporphyrinogen oxidase and sequence analysis suggests that HemK homologs have S-adenosyl-methionine-dependent methyltransferase activity (Medline 99237242). Homologs are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both E. coli and H. influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain. [Protein fate, Protein modification and repair]
Pssm-ID: 273125 [Multi-domain] Cd Length: 284 Bit Score: 51.59 E-value: 2.83e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 445940840 231 EIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEalDRCEFMINNALSGVEPFRFNAVLCNPPF 308
Cdd:TIGR00536 117 HILDLGTGSGCIALALAYEFPNAEVIAVDISPDALAVAEENAEKNQLE--HRVEFIQSNLFEPLAGQKIDIIVSNPPY 192
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
232-352 |
3.03e-06 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 46.64 E-value: 3.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLDK-NPQAKVVFVDESPMAVASSRLNVETNmpeALDRCEFM---INNALSGVEPFRFNAVLCNPP 307
Cdd:pfam13847 7 VLDLGCGTGHLSFELAEElGPNAEVVGIDISEEAIEKARENAQKL---GFDNVEFEqgdIEELPELLEDDKFDVVISNCV 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 445940840 308 FHQQhALTDNVAWEMFhharRCLKINGELYIV-ANRHLDYFHKLKK 352
Cdd:pfam13847 84 LNHI-PDPDKVLQEIL----RVLKPGGRLIISdPDSLAELPAHVKE 124
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
224-308 |
4.81e-06 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 46.82 E-value: 4.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 224 LPENL---EGEIV-DLGCGNGVIGLTLLDKNpqAKVVFVDESPMAVASSRLNVETNMPEALDrCEFMINNALSGVEPFRF 299
Cdd:PRK14968 15 LAENAvdkKGDRVlEVGTGSGIVAIVAAKNG--KKVVGVDINPYAVECAKCNAKLNNIRNNG-VEVIRSDLFEPFRGDKF 91
|
....*....
gi 445940840 300 NAVLCNPPF 308
Cdd:PRK14968 92 DVILFNPPY 100
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
217-338 |
9.39e-06 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 44.62 E-value: 9.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 217 ARFFMQHLPENleGEIVDLGCGNGVIGLTLLDKNpqAKVVFVDESPMAVASSRLNVETNmpealdRCEFMINNALS-GVE 295
Cdd:COG2227 15 AALLARLLPAG--GRVLDVGCGTGRLALALARRG--ADVTGVDISPEALEIARERAAEL------NVDFVQGDLEDlPLE 84
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 445940840 296 PFRFNAVLCNPPFHqqHaLTDnvAWEMFHHARRCLKINGELYI 338
Cdd:COG2227 85 DGSFDLVICSEVLE--H-LPD--PAALLRELARLLKPGGLLLL 122
|
|
| COG2263 |
COG2263 |
Predicted RNA methylase [General function prediction only]; |
210-308 |
2.90e-05 |
|
Predicted RNA methylase [General function prediction only];
Pssm-ID: 441864 [Multi-domain] Cd Length: 199 Bit Score: 44.51 E-value: 2.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 210 RTGLDIGARFFMQ-HLPENLEGE-IVDLGCGNGVIGLTLLDKNPQaKVVFVDESPMAVASSRLNVETNMPEAldrcEFMI 287
Cdd:COG2263 25 PTPAELAAELLHLaYLRGDIEGKtVLDLGCGTGMLAIGAALLGAK-KVVGVDIDPEALEIARENAERLGVRV----DFIR 99
|
90 100
....*....|....*....|.
gi 445940840 288 NNALSGVEPFRFNAVLCNPPF 308
Cdd:COG2263 100 ADVTRIPLGGSVDTVVMNPPF 120
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
217-339 |
4.02e-05 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 43.06 E-value: 4.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 217 ARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNpqAKVVFVDESPMAVASSRlnveTNMPEALDRCEFMINNALSgvEP 296
Cdd:COG2226 11 REALLAALGLRPGARVLDLGCGTGRLALALAERG--ARVTGVDISPEMLELAR----ERAAEAGLNVEFVVGDAED--LP 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 445940840 297 FR---FNAVLCNPPFhqqHALTDNVAweMFHHARRCLKINGELYIV 339
Cdd:COG2226 83 FPdgsFDLVISSFVL---HHLPDPER--ALAEIARVLKPGGRLVVV 123
|
|
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
232-307 |
6.28e-05 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 44.78 E-value: 6.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 232 IVDLGCGNGVIGLTLLDKnpQAKVVFVDESPMAVASSRLNVETNmpeALDRCEF-------MINNALSGvepFRFNAVLC 304
Cdd:COG2265 237 VLDLYCGVGTFALPLARR--AKKVIGVEIVPEAVEDARENARLN---GLKNVEFvagdleeVLPELLWG---GRPDVVVL 308
|
...
gi 445940840 305 NPP 307
Cdd:COG2265 309 DPP 311
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
215-346 |
1.37e-04 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 42.60 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 215 IGARFFMQHLPENleGEIVDLGCGNGVIgLTLLDKNPQAKVVFVDESPMAVASSRlnvETNMPEALDRCEFmINNALSGV 294
Cdd:COG0500 15 AALLALLERLPKG--GRVLDLGCGTGRN-LLALAARFGGRVIGIDLSPEAIALAR---ARAAKAGLGNVEF-LVADLAEL 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 445940840 295 EPF---RFNAVLCNPPFH-QQHALTDnvawEMFHHARRCLKINGELYIVANRHLDY 346
Cdd:COG0500 88 DPLpaeSFDLVVAFGVLHhLPPEERE----ALLRELARALKPGGVLLLSASDAAAA 139
|
|
| PRK14967 |
PRK14967 |
putative methyltransferase; Provisional |
186-308 |
1.94e-04 |
|
putative methyltransferase; Provisional
Pssm-ID: 184931 [Multi-domain] Cd Length: 223 Bit Score: 42.35 E-value: 1.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 186 APQTVSWKLegtdwtihnhANVFSRTGLDIGARffmqhlpenlegeIVDLGCGNGVIGLTLLDKNPqAKVVFVDESPMAV 265
Cdd:PRK14967 17 RPQEDTQLL----------ADALAAEGLGPGRR-------------VLDLCTGSGALAVAAAAAGA-GSVTAVDISRRAV 72
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 445940840 266 ASSRLNVETN-MPEALDRCEFminnaLSGVEPFRFNAVLCNPPF 308
Cdd:PRK14967 73 RSARLNALLAgVDVDVRRGDW-----ARAVEFRPFDVVVSNPPY 111
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
217-353 |
3.07e-03 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 38.44 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 217 ARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKnpQAKVVFVDESPMAVASSRlnvETNMPEALDRCEFminNALSgVEP 296
Cdd:COG4976 35 AEELLARLPPGPFGRVLDLGCGTGLLGEALRPR--GYRLTGVDLSEEMLAKAR---EKGVYDRLLVADL---ADLA-EPD 105
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 445940840 297 FRFNAVLCNPPFHQQHALTdnvawEMFHHARRCLKINGELYIVANRH---LDYFHKLKKI 353
Cdd:COG4976 106 GRFDLIVAADVLTYLGDLA-----AVFAGVARALKPGGLFIFSVEDAdgsGRYAHSLDYV 160
|
|
| PrmA |
pfam06325 |
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ... |
228-275 |
4.09e-03 |
|
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.
Pssm-ID: 428888 [Multi-domain] Cd Length: 294 Bit Score: 38.79 E-value: 4.09e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 445940840 228 LEGEIV-DLGCGNGV--IGLTLLDKnpqAKVVFVDESPMAVASSRLNVETN 275
Cdd:pfam06325 160 KPGESVlDVGCGSGIlaIAALKLGA---KKVVGVDIDPVAVRAAKENAELN 207
|
|
| PRK01544 |
PRK01544 |
bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) ... |
232-308 |
6.53e-03 |
|
bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase; Reviewed
Pssm-ID: 234958 [Multi-domain] Cd Length: 506 Bit Score: 38.31 E-value: 6.53e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 445940840 232 IVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNmpEALDRCEFMINNALSGVEPFRFNAVLCNPPF 308
Cdd:PRK01544 142 ILELGTGSGCIAISLLCELPNANVIATDISLDAIEVAKSNAIKY--EVTDRIQIIHSNWFENIEKQKFDFIVSNPPY 216
|
|
| PRK01683 |
PRK01683 |
trans-aconitate 2-methyltransferase; Provisional |
217-289 |
7.99e-03 |
|
trans-aconitate 2-methyltransferase; Provisional
Pssm-ID: 234970 Cd Length: 258 Bit Score: 37.62 E-value: 7.99e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 445940840 217 ARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRlnvetnmpEALDRCEFMINN 289
Cdd:PRK01683 20 ARDLLARVPLENPRYVVDLGCGPGNSTELLVERWPAARITGIDSSPAMLAEAR--------SRLPDCQFVEAD 84
|
|
| |
