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Conserved domains on  [gi|446081159|ref|WP_000159014|]
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MULTISPECIES: DNA/RNA non-specific endonuclease [Staphylococcus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Endonuclea_NS_2 pfam13930
DNA/RNA non-specific endonuclease;
473-604 1.08e-35

DNA/RNA non-specific endonuclease;


:

Pssm-ID: 433587  Cd Length: 133  Bit Score: 130.56  E-value: 1.08e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446081159  473 NIEYTTPTGHIYRTDHKGRIKEVYVDNLSLKDGGRNNHAQRTVGGE----DRLPDDDGGHLIARMFGGSKDIDNLVAQSK 548
Cdd:pfam13930   2 NTIYGAEWGYTYDTDSLGRITRANADLNLMPTEKRNPYQQNPPGKWnkkaNPGWLYDGGHLIASQFGGSGDNDNLVPMTS 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446081159  549 YINRsfkenGDWYKLEKLWEK--AIKSGKSIEnIKIEVKYKGNSQRPTIFKVEYEING 604
Cdd:pfam13930  82 NLNR-----GKMLQMENQWAKylALSPGKKVR-YRVTPIYRGNSLRPSGFEVEYKIDG 133
PT-TG super family cl16891
Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could ...
 248-292 2.06e-03

Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could function as a linker that links N-terminal secretion-related domain and C-terminal toxin domain. It contains a TG motif.


The actual alignment was detected with superfamily member pfam14449:

Pssm-ID: 433960  Cd Length: 68  Bit Score: 36.94  E-value: 2.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 446081159  248 TGKNIVTGRKLSKEERIMEGLSLIPlPGMGFLKGAGKSLMKlGFK 292
Cdd:pfam14449  26 TGRDPITGEKLSDWDRLLAGAMAVP-GGVGKLGKKGKALVK-GLK 68
 
Name Accession Description Interval E-value
Endonuclea_NS_2 pfam13930
DNA/RNA non-specific endonuclease;
473-604 1.08e-35

DNA/RNA non-specific endonuclease;


Pssm-ID: 433587  Cd Length: 133  Bit Score: 130.56  E-value: 1.08e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446081159  473 NIEYTTPTGHIYRTDHKGRIKEVYVDNLSLKDGGRNNHAQRTVGGE----DRLPDDDGGHLIARMFGGSKDIDNLVAQSK 548
Cdd:pfam13930   2 NTIYGAEWGYTYDTDSLGRITRANADLNLMPTEKRNPYQQNPPGKWnkkaNPGWLYDGGHLIASQFGGSGDNDNLVPMTS 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446081159  549 YINRsfkenGDWYKLEKLWEK--AIKSGKSIEnIKIEVKYKGNSQRPTIFKVEYEING 604
Cdd:pfam13930  82 NLNR-----GKMLQMENQWAKylALSPGKKVR-YRVTPIYRGNSLRPSGFEVEYKIDG 133
PT-TG pfam14449
Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could ...
 248-292 2.06e-03

Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could function as a linker that links N-terminal secretion-related domain and C-terminal toxin domain. It contains a TG motif.


Pssm-ID: 433960  Cd Length: 68  Bit Score: 36.94  E-value: 2.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 446081159  248 TGKNIVTGRKLSKEERIMEGLSLIPlPGMGFLKGAGKSLMKlGFK 292
Cdd:pfam14449  26 TGRDPITGEKLSDWDRLLAGAMAVP-GGVGKLGKKGKALVK-GLK 68
 
Name Accession Description Interval E-value
Endonuclea_NS_2 pfam13930
DNA/RNA non-specific endonuclease;
473-604 1.08e-35

DNA/RNA non-specific endonuclease;


Pssm-ID: 433587  Cd Length: 133  Bit Score: 130.56  E-value: 1.08e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446081159  473 NIEYTTPTGHIYRTDHKGRIKEVYVDNLSLKDGGRNNHAQRTVGGE----DRLPDDDGGHLIARMFGGSKDIDNLVAQSK 548
Cdd:pfam13930   2 NTIYGAEWGYTYDTDSLGRITRANADLNLMPTEKRNPYQQNPPGKWnkkaNPGWLYDGGHLIASQFGGSGDNDNLVPMTS 81

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446081159  549 YINRsfkenGDWYKLEKLWEK--AIKSGKSIEnIKIEVKYKGNSQRPTIFKVEYEING 604
Cdd:pfam13930  82 NLNR-----GKMLQMENQWAKylALSPGKKVR-YRVTPIYRGNSLRPSGFEVEYKIDG 133
PT-TG pfam14449
Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could ...
 248-292 2.06e-03

Pre-toxin TG; PT-TG is a conserved region found in many bacterial toxin proteins. It could function as a linker that links N-terminal secretion-related domain and C-terminal toxin domain. It contains a TG motif.


Pssm-ID: 433960  Cd Length: 68  Bit Score: 36.94  E-value: 2.06e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 446081159  248 TGKNIVTGRKLSKEERIMEGLSLIPlPGMGFLKGAGKSLMKlGFK 292
Cdd:pfam14449  26 TGRDPITGEKLSDWDRLLAGAMAVP-GGVGKLGKKGKALVK-GLK 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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