|
Name |
Accession |
Description |
Interval |
E-value |
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
51-688 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 552.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLPGMNHAAssyVV 130
Cdd:COG0210 7 LNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRLARG---LW 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 131 AGTFHSVFLKLLRS----QGY--NQQIL-ANEKHKqiMIKKILKELRLKDDYDS-ETILAMISLEKNKLNRPKDVK---A 199
Cdd:COG0210 84 VGTFHSLALRILRRhaelLGLppNFTILdGDDQLR--LIKELLKELGLDEKRFPpRELLSLISRAKNEGLTPEELAellA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 200 KTPVEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNN 279
Cdd:COG0210 162 ADPEWRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAGDGRN 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 280 LFIAGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREEGVQPFYAR 359
Cdd:COG0210 242 LCVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEGEKVRLYV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 360 PATTLDEANQILQLIQEKVDSGdRNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGaSQSFYEHSLIKPVLDHLRLVIE 439
Cdd:COG0210 322 APDEEEEARFVADEIRELHEEG-VPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVG-GLRFYERAEIKDLLAYLRLLAN 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 440 PFRLESLSNIL--PTMYIGRDDcisfIER-EQWKYGEGR-FPSLLHFLLLNPSLKPFQVKKVNERIDFIKFIKE----LE 511
Cdd:COG0210 400 PDDDVALLRILnvPRRGIGAAT----LERlREAAREEGIsLLEALRDLGELAGLSGRAAKALRRFAELLEALRAaaerLP 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 512 PKKALKEIIHGKGkYLEYLQ-SNDRSSFTMHKDIQeemleELMESATRFTD------IPAYLQFIDEAiqgqkeMEALKT 584
Cdd:COG0210 476 LEELLEALLDESG-YEEELReEAGEEAERRLENLE-----ELVDAAARFEErnpgasLEAFLEELALL------SDLDAA 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 585 MPQKDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDAndritetsEALEEERRLLYVAITRAKEELYISSPQ--F 662
Cdd:COG0210 544 DEDEDAVTLMTLHAAKGLEFPVVFLVGLEEGLFPHQRSLDDE--------EELEEERRLFYVAITRARERLYLTYAAsrR 615
|
650 660
....*....|....*....|....*...
gi 446113356 663 FRGKKLD--ISRFLYTVRKDLPEKTSTK 688
Cdd:COG0210 616 LWGETQDnePSRFLDELPEELLEWVRPK 643
|
|
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
51-688 |
5.72e-139 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 424.18 E-value: 5.72e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLPGmnhAASSYVV 130
Cdd:TIGR01073 5 LNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLG---PVAEDIW 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 131 AGTFHSVFLKLLRSQ----GYNQQI-LANEKHKQIMIKKILKELRL-KDDYDSETILAMISLEKNKLNRPKDVKAKTP-- 202
Cdd:TIGR01073 82 ISTFHSMCVRILRRDidriGINRNFsIIDPTDQLSLMKTILKDKNLdPKKFEPRSILGTISNAKNELLPPEDFAKEATny 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 203 VEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNNLFI 282
Cdd:TIGR01073 162 FEKVVAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRFRNLCV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 283 AGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREEGVQPFYARPAT 362
Cdd:TIGR01073 242 VGDADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDKITYYEADT 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 363 TLDEANQILQLIQEKVDSGDRNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGAsQSFYEHSLIKPVLDHLRLVIEPFR 442
Cdd:TIGR01073 322 ERDEAQFVAGEIDKLVKNGERKYGDFAILYRTNAQSRVFEETLLKANIPYKIVGG-LKFYDRKEIKDILAYLRVIANPDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 443 LESLSNIL--PTMYIGRddciSFIEREQwKYGEGR---FPSLLHFLLLNPSLKPFQVKKV---NERID-FIKFIKELEPK 513
Cdd:TIGR01073 401 DLSLLRIInvPKRGIGA----SSLEKIV-NYALELnisLFEAIGEIDEIGGLAAKSANALlafATMIEnLRQQQEYLSPT 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 514 KALKEIIHGKGkYLEYL-QSNDRSSFTMHKDIQeemleeLMESATR-FTDIPAYLQFID--EAIQGQKEMEALKTMPQKD 589
Cdd:TIGR01073 476 ELVEEVLDKSG-YREMLkAEKTEEAQSRLENLD------EFLSVTKeFEDESEDKSLIDflTDLALVSDLDELEETEEGG 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 590 AVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDritetseaLEEERRLLYVAITRAKEELYISSPQ----FFRG 665
Cdd:TIGR01073 549 AVTLMTLHAAKGLEFPVVFLIGMEEGVFPHSRSLMDEKE--------LEEERRLAYVGITRAEEELYLTHATmrtlFGRI 620
|
650 660
....*....|....*....|...
gi 446113356 666 KKLDISRFLYTVRKDLPEKTSTK 688
Cdd:TIGR01073 621 QMNPPSRFLNEIPAELLETASTG 643
|
|
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
51-674 |
3.52e-110 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 347.51 E-value: 3.52e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLpgMNHAASSYVV 130
Cdd:TIGR01074 2 LNPQQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYLIQNCGYKARNIAAVTFTNKAAREMKERVAKT--LGKGEARGLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 131 AGTFHSVFLKLLRSQ----GYNQQILANEKHKQIMIKKILKELRLKDDYDS-ETILAMISLEKNKLNRPKDV--KAKTPV 203
Cdd:TIGR01074 80 ISTFHTLGLDIIKREynalGYKSNFSLFDETDQLALLKELTEGLIKDDKDLlDKLISTISNWKNDLLTPEQAlaSARGER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 204 EQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNNLFIA 283
Cdd:TIGR01074 160 EQTFAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVGDRARFTVV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 284 GDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREEGVQPFYARPATT 363
Cdd:TIGR01074 240 GDDDQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIKVIECNNE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 364 LDEANQIL-QLIQEKVdSGDRNYKDFCLLYRTHSVSRSLLDQLTIHKIPFiKHGASQSFYEHSLIKPVLDHLRLVIEPFR 442
Cdd:TIGR01074 320 EHEAERIAgEIIAHKL-VNKTQYKDYAILYRGNHQSRLLEKALMQNRIPY-KLSGGTSFFSRPEIKDLLSYLRLLVNPDD 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 443 LESLSNIL--PTMYIGrDDCISFIEREQWKYGEGRFPSLLHFLLLNpSLKPFQVKKVNERIDFIKFIKEL----EPKKAL 516
Cdd:TIGR01074 398 DAAFLRIVntPKREIG-PATLEKLGELAMERNKSLFTASFDMGLLQ-TLSGRGYESLQRFTDWLVEIRRLaersEPIEAV 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 517 KEIIHGKgKYLEYL--QSNDRSSFTMHKD--------IQEEMLEELMESATRFTDIPAYLQFIDEAIQGQKEMEalktmp 586
Cdd:TIGR01074 476 RSLIEDI-DYENWLyeTSPSPKAAEMRMKnvntlfswFKEMLEGDEEDEPMTLTQVVTRLTLRDMLERGEDEEE------ 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 587 qKDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANdritetseaLEEERRLLYVAITRAKEELYISSPQFFR-- 664
Cdd:TIGR01074 549 -LDQVQLMTLHASKGLEFPYVFIVGMEEGILPHQSSIEEDN---------VEEERRLAYVGITRAQKELTFTLCKERRqy 618
|
650
....*....|..
gi 446113356 665 GKKLDI--SRFL 674
Cdd:TIGR01074 619 GELVRPepSRFL 630
|
|
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
51-658 |
1.05e-102 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 329.52 E-value: 1.05e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLPGMNhaaSSYVV 130
Cdd:PRK11773 10 LNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGTS---QGGMW 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 131 AGTFHSVFLKLLRS--------QGYnqQILANEKhKQIMIKKILKELRLKDD-YDSETILAMISLEKNKLNRPKDVKAKT 201
Cdd:PRK11773 87 VGTFHGLAHRLLRAhwqdanlpQDF--QILDSDD-QLRLLKRLIKALNLDEKqWPPRQAQWYINGQKDEGLRPQHIQSYG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 202 -PVEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNNL 280
Cdd:PRK11773 164 dPVEQTWLKIYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDTGKV 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 281 FIAGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREEGvQP--FYA 358
Cdd:PRK11773 244 MIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDG-EPisLYC 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 359 rpA-TTLDEANQILQLIQEKVDSGdRNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGAsQSFYEHSLIKPVLDHLRLV 437
Cdd:PRK11773 323 --AfNELDEARFVVERIKTWQDNG-GALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGG-MRFFERQEIKDALAYLRLI 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 438 IepFR-----LESLSNIlPTMYIGRD--DCISFIEREQ----W---------KYGEGRFPS-LLHFLLLNPSLK------ 490
Cdd:PRK11773 399 A--NRnddaaFERVVNT-PTRGIGDRtlDVVRQTARDRqltlWqacrallqeKVLAGRAASaLQRFIELIDALAqetadm 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 491 --PFQVKKVNERIDFIKFIKELEPKKALKEIihgkgKYLEYLQSNDRsSFTMHKDIQEEmleelmesatrfTDIPAYLQF 568
Cdd:PRK11773 476 plHEQTDRVIKDSGLRAMYEQEKGEKGQARI-----ENLEELVTATR-QFSYPDEDEDL------------TPLQAFLSH 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 569 ID-EAIQGQKEmealktmPQKDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDAnDRitetseaLEEERRLLYVA 647
Cdd:PRK11773 538 AAlEAGEGQAD-------AHEDAVQLMTLHSAKGLEFPLVFIVGMEEGLFPSQMSLEEG-GR-------LEEERRLAYVG 602
|
650
....*....|.
gi 446113356 648 ITRAKEELYIS 658
Cdd:PRK11773 603 ITRAMQKLTLT 613
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
51-683 |
5.30e-100 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 322.14 E-value: 5.30e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLpgMNHAASSYVV 130
Cdd:TIGR01075 5 LNDKQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGAL--LGTSARGMWI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 131 aGTFHSVFLKLLRSQGY------NQQILANEKhKQIMIKKILKELRLKDD-YDSETILAMISLEKNKLNRPKDVKA-KTP 202
Cdd:TIGR01075 83 -GTFHGLAHRLLRAHHLdaglpqDFQILDSDD-QLRLLKRLIKALNLDEKqWPPRQAMWYINNQKDEGLRPSHIQAfDNP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 203 VEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNNLFI 282
Cdd:TIGR01075 161 VERTWIKIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGNTGNVMI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 283 AGDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREEGVQPFYARPAT 362
Cdd:TIGR01075 241 VGDDDQSIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISLYSAFN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 363 TLDEANQILQLIQEKVDSGDrNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGAsQSFYEHSLIKPVLDHLRLVIEP-- 440
Cdd:TIGR01075 321 ELDEARFVVSRIKTWQRNGG-ALDECAVLYRSNAQSRVLEEALLQASIPYRIYGG-MRFFERQEIKDALAYLRLIANRnd 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 441 -FRLESLSNIlPTMYIGRD--DCISFIEREQ----W---------KYGEGRFPS-LLHFLLLNPSLKPFQVK-KVNERID 502
Cdd:TIGR01075 399 dAAFERVINT-PTRGIGDRtlDVVRQAARDRgltlWqaareltqeKVLAGRAASaLQRFVELIEALANETADmPLHVQTD 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 503 FIkfIKELEPKKALKEIIHGKGKY----LEYLQSNDRsSFTMHKDIQEemleelmesatrFTDIPAYLQFID-EAIQGQK 577
Cdd:TIGR01075 478 HV--IKDSGLREMYQQEKGEKGQArienLEELVTATR-QFSLPENDED------------MTPLTAFLSHAAlEAGEGQA 542
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 578 EmealktmPQKDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANdritetseALEEERRLLYVAITRAKEELYI 657
Cdd:TIGR01075 543 D-------AGQDAVQLMTLHSAKGLEFPLVFLVGMEEGMFPSQMSLDEGG--------RLEEERRLAYVGITRAMQKLTI 607
|
650 660 670
....*....|....*....|....*....|
gi 446113356 658 SSPQFFR--GKKL--DISRFLytvrKDLPE 683
Cdd:TIGR01075 608 TYAETRRlyGKEVyhIPSRFI----RELPE 633
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
51-309 |
2.58e-83 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 264.11 E-value: 2.58e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLpgMNHAASSYVV 130
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKL--LGKAELSELN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 131 AGTFHSVFLKLLRSQGYNQQILAN-----EKHKQIMIKKILKELRLKDD---YDSETILAMISLEKNKLNRPKDVK--AK 200
Cdd:pfam00580 79 ISTFHSFCLRILRKYANRIGLLPNfsildELDQLALLKELLEKDRLNLDpklLRKLELKELISKAKNRLLSPEELQqgAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 201 TPVEQEFKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNNL 280
Cdd:pfam00580 159 DPRDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGHENL 238
|
250 260
....*....|....*....|....*....
gi 446113356 281 FIAGDDDQAIYGWRGASHQIILSFPKEFD 309
Cdd:pfam00580 239 FLVGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
51-680 |
6.71e-81 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 270.56 E-value: 6.71e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLPGMNHAASsyVV 130
Cdd:PRK10919 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLGRKEARG--LM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 131 AGTFHSVFLKLLRSQ----GYNQQILANEKHKQIMIKKILKELRLKDDYDS-ETILAMISLEKNKLNRPKDVKAKTPVEQ 205
Cdd:PRK10919 81 ISTFHTLGLDIIKREyaalGMKSNFSLFDDTDQLALLKELTEGLIEDDKVLlQQLISTISNWKNDLKTPAQAAAGAKGER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 206 E--FKEVYERFEEVKQRYNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNNLFIA 283
Cdd:PRK10919 161 DriFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 284 GDDDQAIYGWRGASHQIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREEGVQPFYARPATT 363
Cdd:PRK10919 241 GDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKVLSANNE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 364 LDEANQIL-QLIQEKVDSgDRNYKDFCLLYRTHSVSRSLLDQLTIHKIPFIKHGASqSFYEHSLIKPVLDHLRLVIEPFR 442
Cdd:PRK10919 321 EHEAERVTgELIAHHFVN-KTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGT-SFFSRPEIKDLLAYLRVLTNPDD 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 443 LESLSNIL--PTMYIGRddcISFIEREQWKYGEGR------FPSLLHFLLLNPSLKPFQvkKVNERIDFIKFIKELEPKK 514
Cdd:PRK10919 399 DSAFLRIVntPKREIGP---ATLQKLGEWAMTRNKslftasFDMGLSQTLSGRGYESLT--RFTHWLAEIQRLAEREPVA 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 515 ALKEIIHG------------KGKYLEYLQSNDRSSFT----MHKDIQEEMLEELMESATRFTdipaylqFIDEAIQGQKE 578
Cdd:PRK10919 474 AVRDLIHGidyeswlyetspSPKAAEMRMKNVNQLFSwmteMLEGSELDEPMTLTQVVTRFT-------LRDMMERGESE 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 579 MEAlktmpqkDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANdritetseaLEEERRLLYVAITRAKEELYIS 658
Cdd:PRK10919 547 EEL-------DQVQLMTLHASKGLEFPYVYLVGMEEGLLPHQSSIDEDN---------IDEERRLAYVGITRAQKELTFT 610
|
650 660
....*....|....*....|....*.
gi 446113356 659 ----SPQFFRGKKLDISRFLYTVRKD 680
Cdd:PRK10919 611 lckeRRQYGELVRPEPSRFLLELPQD 636
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
52-320 |
6.90e-77 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 244.35 E-value: 6.90e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 52 NEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAKLPGmNHAASSyVVA 131
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLG-EQLASG-VWI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 132 GTFHSVFLKLLRsqgynqqilanekhkqimikkilkelrlkddydsetilamisleknklnrpkdvkaktpveqefkevy 211
Cdd:cd17932 79 GTFHSFALRILR-------------------------------------------------------------------- 90
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 212 erfeevkqryNYIDFDDILLETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLATPRNNLFIAGDDDQAIY 291
Cdd:cd17932 91 ----------RYGDFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKNLFVVGDDDQSIY 160
|
250 260
....*....|....*....|....*....
gi 446113356 292 GWRGASHQIILSFPKEFDNTTIIALNTNY 320
Cdd:cd17932 161 GFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
51-658 |
4.41e-74 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 256.04 E-value: 4.41e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 51 LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRSRVAK-----------LP 119
Cdd:COG1074 6 WTDAQRRALDPLGGSVLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIRErlaeaadledpDL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 120 GMNHAASSYVVA----------GTFHSVFLKLLRSQGY------NQQILANEKhkQIMIKKILKEL-------------- 169
Cdd:COG1074 86 EELARARRRLARalenldraaiSTIHSFCQRLLREFAFeagldpNFELLDDAE--ALLLEEAVDDLlreayapldalala 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 170 RLKDDYDS------ETILAMISLEKN-----------------------KLNRPKDVKAKTPVEQE---------FKEVY 211
Cdd:COG1074 164 RLLDAFGRdddsleELLLALYKLRSRpdwleelaeldealealreallkAKEALAALREALAAAAApllaallrlLAAVL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 212 ERFEEVKQRYNYIDFDDILLETYYMLENNAP--LLTQLQQRFHYIEVDEFQDTSYAQYEIVKLLA----TPRNNLFIAGD 285
Cdd:COG1074 244 ARYERRKRERGLLDFDDLLHRALRLLRDEDApwVAERLRERYRHILVDEFQDTSPLQWEILRRLAgealADGRTLFLVGD 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 286 DDQAIYGWRGASHQIILSFPKEFDN---TTIIALNTNYRSNPFIVGLGNEVIklnQERFDKELYSVREEGVQPFY--ARP 360
Cdd:COG1074 324 PKQSIYRFRGADPELFLEARRALEGrvdGERLTLTTNFRSTPEVVDAVNALF---AQLMGAGFGEIPYEPVEALRpgAYP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 361 ATTL---------------DEANQILQLIQEKVDSGDR--------NYKDFCLLYRTHSVSRSLLDQLTIHKIPFIkHGA 417
Cdd:COG1074 401 AVELwplepddvseedareREARAVAARIRRLLAEGTTvegggrpvRPGDIAVLVRTRSEAAAIARALKAAGIPVA-ASD 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 418 SQSFYEHSLIKPVLDHLRLVIEPFRLESLSNILPTMYIGRDDciSFIEREQWKYGEGRFPSLLhflllnpslkpFQVKKV 497
Cdd:COG1074 480 RLSLFESPEVRDLLALLRALLNPEDDLALAAVLRSPLFGLSD--EDLAALAADRKGESLWEAL-----------RAYERL 546
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 498 NERIDFIKFIKELEPKKALKEIIH---GKGKYLEYLQSND--RSSFTMHKDIQEEMLEELMESATRFTDIPAYLQFIDEA 572
Cdd:COG1074 547 ARALERLRALRELARRLGLAELLErllEETGLLERLLALPggERRLANLLHLDELLQLALEYEQTGGPGLAGFLRWLERL 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 573 IQGQKEMEALKTMPQKDAVSLMSIHNAKGLEFPCVFLLgasdgilphtsSLKDANDRitetsEALEEERRLLYVAITRAK 652
Cdd:COG1074 627 IEDGGDEEKRRLESDADAVRIMTIHKSKGLEFPVVFLP-----------ALRERARA-----EELAEELRLLYVALTRAR 690
|
....*.
gi 446113356 653 EELYIS 658
Cdd:COG1074 691 DRLVLS 696
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
314-658 |
3.07e-37 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 143.32 E-value: 3.07e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 314 IALNTNYRSNPFIVGLGNEVIKLNQER----FDKELYSVREEGVQPFYARPATTLDEANQILQLIQEKVDSGDrNYKDFC 389
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRatiyPKKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLVARDE-KYNDIA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 390 LLYRTHSVSRSLLDQLTIHKIPFIKHGaSQSFYEHSLIKPVLDHLRLVIEPFRLESLSNILPTMYIGRDDCISFIEREQW 469
Cdd:pfam13361 80 VLTRSNSDADLIEEALKKLGIPYFVVG-QTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIREYK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 470 KYGegrfpSLLHFLLLNPSLK---PFQVKKVNERI---------------DFIK---------------FIKELEPKKAL 516
Cdd:pfam13361 159 KRG-----LRLSDFINPDTLTygdPFVIALEQDNIvvfdvettgldttedEIIQiaaiklnkkgvviesFERFLRLKKPV 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 517 KEIIHGKGKYLEYLQSNDRSSFTMHKDI-QEEMLEELMESATRFTDIPAYLQFIDEAIQGQKEMEALK-----TMPQKDA 590
Cdd:pfam13361 234 GDSLQVHGFSDEFLQENGETPAEALRDFlEKLENLRELYSILREYDDIEETPEPEDALRNFLEIATLSnseleGSDIKER 313
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446113356 591 VSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDritetseaLEEERRLLYVAITRAKEELYIS 658
Cdd:pfam13361 314 IPIMTIHQAKGLEFDTVFLAGLEEGIFPSYRSIKDEGN--------LEEERRLFYVAITRAKKRLYIS 373
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
72-683 |
7.09e-30 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 126.40 E-value: 7.09e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 72 AGSGKTSVLTTRVgyLVNVKQVHPrnILLLTFTQKAAEEIRSRVAKLPGmnhAASSYVVAGTFHSVFLKLLRSQGYNQQI 151
Cdd:COG3857 7 AGSGKTTYLLEEI--KEELKEGKP--IILLVPEQMTFQAERALLKRLGL---GGSIRAQVLSFSRLAWRVLQETGGATRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 152 LANEKHKQIMIKKILKELR-----LKDDYDS----ETILAMISLEKNKLNRPKDVKAKTPVE----QEFKEVYERFEEVK 218
Cdd:COG3857 80 LLSDAGKRMLLRKILEEHKdelkvFARAADKpgfiEQLAELITELKRYGITPEDLEEAAELLkeklRDLALIYEAYEEKL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 219 QRyNYIDFDDILletyYMLENNAPLLTQLQQrfHYIEVDEFQDTSYAQYEIVKLLATPRNNLFIAGDDDQAIYGWRGASH 298
Cdd:COG3857 160 AG-RYIDSEDLL----RLLAEKLEKSEFLEG--AEIYIDGFTDFTPQELELLEALLKKAKEVTITLTLDPDELDLFSATG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 299 QIILSFPKEFDNTTIialNTNYRSNPFIVGLgneviklnQERFDKELYSVREEGVQPFYArpATTLDEANQILQLIQEKV 378
Cdd:COG3857 233 ETYERLLELAKENGV---EVEFKKSPELAHL--------ERNLFAYPPEEEPEGIEIIEA--ANRRAEVEAVAREIRRLV 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 379 DSGDRNYKDFCLLYRTHSVSRSLLDQ-LTIHKIP-FIKHGasQSFYEHSLIKPVLDHLRLVIEPFRLESLSNILPTMYIG 456
Cdd:COG3857 300 REEGYRYRDIAVVVRDLEAYAPLIERvFAEYGIPyFIDEK--RPLSHHPLVELILSLLELVRSNFRYEDVFRLLKTGLLR 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 457 R--DDCISFIE---REQWKYGEGRFPSLLHFLLLNPSLKPFQVKKVNE-----RIDFIKFIKELEPKKALKEIIHGKGKY 526
Cdd:COG3857 378 PlsREEIDRLEnyvLAYGIRGRRWLERYLEEEEELTDEEEEDLERLNElrdrlLEPLLPLRERLKKAKTVREWAEALYEF 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 527 LEYLQSNDRssftMHKDIQEEMLEELMESATRFTDIPAYLQFIDE--AIQGQKEM------EALKTM----------PQK 588
Cdd:COG3857 458 LEELGVPEK----LEEWREAEEAGDLEEAREHEQAWNALIELLDElvEVLGDEKLsleeflRILESGleeltfglipPSL 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 589 DAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSS------------LKDANDRITETS-EALEEERRLLYVAITRAKEEL 655
Cdd:COG3857 534 DQVQVGGLDRARGLDFKAVFVLGLNEGVFPARPRedgllsdeererLNELGLELPPTSrERLLEERFLFYRALTRASERL 613
|
650 660
....*....|....*....|....*....
gi 446113356 656 YISSPQF-FRGKKLDISRFLYTVRKDLPE 683
Cdd:COG3857 614 YLSYPLAdEEGKALLPSPLIDRLRELFPE 642
|
|
| recB |
TIGR00609 |
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with ... |
208-657 |
3.20e-28 |
|
exodeoxyribonuclease V, beta subunit; The RecBCD holoenzyme is a multifunctional nuclease with potent ATP-dependent exodeoxyribonuclease activity. Ejection of RecD, as occurs at chi recombinational hotspots, cripples exonuclease activity in favor of recombinagenic helicase activity. All proteins in this family for which functions are known are DNA-DNA helicases that are used as part of an exonuclease-helicase complex (made up of RecBCD homologs) that function to generate substrates for the initiation of recombination and recombinational repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273172 [Multi-domain] Cd Length: 1087 Bit Score: 121.38 E-value: 3.20e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 208 KEVYERFEEVKQRYNYIDFDDIL--LETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLL--ATPRNNLFIA 283
Cdd:TIGR00609 252 KEVQEELKKEKKRRREIGFDDLLsrLETALKSAEGEKLAQAIREQYPIALIDEFQDTDPQQYRIFSKLfiAQKETSLFLI 331
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 284 GDDDQAIYGWRGAS----HQIILSFPKEFdnttiiALNTNYRSNPFIVGLGNEVIKLNQERF------------DKE--- 344
Cdd:TIGR00609 332 GDPKQAIYSFRGADiftyLQAKSKADARY------TLGTNWRSTPALVGSLNKLFSLISNPFlekpifipvlahQKNskg 405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 345 ---------------LYSVREEGVQPFYARPATTLdeANQILQLIQEKVdSGDRNYK-----------DFCLLYRTHSVS 398
Cdd:TIGR00609 406 sfvingqeqppihffTTEVESEGVDDYRQTIAQKC--AREIALWLASAA-LGLANFIatfggrplragDIAVLVRGRKEA 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 399 RSLLDQLTIHKIPFIKHG------ASQSFYEHSLIkpvldhLRLVIEPFRLESLSNILPTMYIGR--DDCISFIEREQ-W 469
Cdd:TIGR00609 483 NQIRKALKKAQIPSVYLSdkssvfATEEAQELLAL------LEALLEPENEGTLRAALASSIFGLsaLELETLNQDEItW 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 470 KYGEGRFPSLL----HFLLLnPSLKPFQVKKVNERIDFIKFIKELEpkkaLKEIIHgkgkYLEYLQsndrssftmhkdiq 545
Cdd:TIGR00609 557 ERVVEKFREYHdiwrKIGVL-AMFQRLMLEKGIGERLLSQPGGERI----LTNLLH----LAELLQ-------------- 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 546 eemleelmESATRFTDIPAYLQFIDEAIQ--GQKEMEALKTMPQKDAVSLMSIHNAKGLEFPCVFLLGASDGILPHTSSL 623
Cdd:TIGR00609 614 --------EAAHQERNKLSLLRWLEDQISneEEEEEEIIRLESDAELVKIVTIHKSKGLEYPIVFLPFITDAKKSNFASL 685
|
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 446113356 624 KDANDRITETS--------------EALEEERRLLYVAITRAKEELYI 657
Cdd:TIGR00609 686 HDQHSHEYQLYdfnqseenqklarvERLAEDLRLLYVALTRAKKQLFI 733
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
42-349 |
5.42e-28 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 119.67 E-value: 5.42e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 42 RALEQQNVF--------LNEKQLEAVRTTEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRS 113
Cdd:PRK11054 180 AMLEEYADFfsqvesspLNPSQARAVVNGEDSLLVLAGAGSGKTSVLVARAGWLLARGQAQPEQILLLAFGRQAAEEMDE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 114 RVAKLPGMNHaassyVVAGTFHSVFLKLLRsQGYNQQ----ILAN--EKHKQIMIKKILK------------------EL 169
Cdd:PRK11054 260 RIRERLGTED-----ITARTFHALALHIIQ-QGSKKVpvisKLENdsKARHALLIAEWRKqcsekkaqakgwrqwlteEL 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 170 R----LKDDYDSETILAMIS--LEK-NKLNRPKDVKAKTPVEQEFKEVYERFE---------------EVKQRyNYIDFD 227
Cdd:PRK11054 334 QwdvpEGNFWDDEKLQRRLAsrLERwVSLMRMHGGSQAEMIAQAPEEVRDLFQkrlklmapllkawkkALKAE-NAVDFS 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 228 DILLETYYMLENNaplltqlqqRF----HYIEVDEFQDTSYAQyeiVKLLAT-----PRNNLFIAGDDDQAIYGWRGASH 298
Cdd:PRK11054 413 GLIHQAVNYLEKG---------RFispwKHILVDEFQDISPQR---AALLAAlrkqnSQTTLFAVGDDWQAIYRFSGADL 480
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 446113356 299 QIILSFPKEFDNTTIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVR 349
Cdd:PRK11054 481 SLTTAFHERFGEGDRCHLDTTYRFNSRIGEVANRFIQQNPHQLKKPLNSLT 531
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
591-659 |
1.78e-25 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 102.69 E-value: 1.78e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446113356 591 VSLMSIHNAKGLEFPCVFLLGASDGILPHTSSLKDANDRItetsEALEEERRLLYVAITRAKEELYISS 659
Cdd:cd18807 86 VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASYHAAKEDE----ERLEEERRLLYVALTRAKKELYLVG 150
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
70-657 |
4.61e-19 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 91.96 E-value: 4.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 70 AGAGSGKTSVLTTRVGYLVnVKQVHPRNILLLTFTQKAAEEIRSRV-------------------AKLPGMN-------- 122
Cdd:PRK13909 5 ASAGSGKTFALSVRFLALL-FKGANPSEILALTFTKKAANEMKERIidtllnlekekeeselnelEEKLGLSkeellnkr 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 123 -----HAASSYVVAGTFHSVFLKLLRSQGYNQQILAN----EKHKQIMIKKILKELRlKDDYDSETILAMISLEK----- 188
Cdd:PRK13909 84 dkvyqEFLNSELKISTIDAFFQKILRKFCLNLGLSPDfsikEDTKEELNEKFLSALS-KEELLELLAFIKQCESKknnsf 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 189 ---------NKLNRPKDVKAKTPVEQEFKEVYERFEEVKQRY-------------------------------------- 221
Cdd:PRK13909 163 felleklyeKNNELKLFEKAKNPIEFDEEKFLEELRSLKQQIqsietasknakkafkkedfeellnssktwlekeseyry 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 222 -----------------------------------------------------NYIDFDDILLETYYMLENNAP----LL 244
Cdd:PRK13909 243 fkklyneeldaefeelknalkryydakenyklsklfkllqlykeaknelnkkkNALDFDDISKKVYELLGEEEIdkdfLY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 245 TQLQQRFHYIEVDEFQDTSYAQYEI-------------VKLLATprnnLFIAGDDDQAIYGWRGASHQIILSFPKEFdNT 311
Cdd:PRK13909 323 FRLDSKISHILIDEFQDTSVLQYKIllplideiksgegQKKFRS----FFYVGDVKQSIYRFRGGKKELFDKVSKDF-KQ 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 312 TIIALNTNYRSNPFIVGLGNEVIKLNQERFDKELYSVREEGvqpFYAR--PATTLDEA--NQILQLIQEKVDSGdRNYKD 387
Cdd:PRK13909 398 KVDNLDTNYRSAPLIVDFVNEVFKKKYKNYKTQYAEQHKSG---GYVEvvEVADESEEllEQLLQEIQFLLEKG-IDPDD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 388 FCLLYRTHSVSRSLLDQLTihkipfikhgasqsfyEHSLIKPVldhlrlviepfrLESLSNILPTMYIgrDDCISFIEre 467
Cdd:PRK13909 474 IAILCWTNDDALEIKEFLQ----------------EQFGIKAV------------TESSAKLINQPEV--KALIEALK-- 521
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 468 qwkygegrfpsllhFLLLNpslKPFQVKKVNERI--DFIKFIKELEPKKALKEIIHGKGKYLEYLQSNDRSSFTMhkdiq 545
Cdd:PRK13909 522 --------------YCLFG---EEIYKHNVLKLLgkEPDKIPSFLPKEESVAEFVKKLIEELKLYDENLLKFLEL----- 579
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 546 eemleelmesATRFTDIPAylqFIDEAIQGQKEMEAlktmPQKDAVSLMSIHNAKGLEFPCVFLL-------GASDGILP 618
Cdd:PRK13909 580 ----------ASGYEDIEE---FLFKLEPCDKEIAS----EESKGVQIMTVHKSKGLEFEHVIVCdrlgkpnSDSSNLLF 642
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 446113356 619 HTSS-------LKDAN--------DRITETSEAL--EEERRLLYVAITRAKEELYI 657
Cdd:PRK13909 643 EYDGielwqiyYRIKGrenfdkdyARALEKEKALkyEEEINVLYVAFTRAKNSLIV 698
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
24-659 |
6.11e-14 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 74.87 E-value: 6.11e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 24 PKTSTHLIMEEDVDAAYFRALEQQNVFLNEKQLEAVR-TTEGPVLTLAGAGSGKTSVLTTRVGYLVNVkqvHP-RNILLL 101
Cdd:COG3972 133 PPAPFVQALRLLNLVSLEDFFLPLIAVLDLQQERIARsIPDGPQRIRGVAGSGKTVLLAAKAAYLALK---HPgWRILVT 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 102 TFTQKAAEEIRSRVAK--LPGMNHAASSYVVAGTFHSVFLKLLRSQGynqqilanekhkqimikkilkelrlkddydset 179
Cdd:COG3972 210 CFNRSLADHLRDLIPRflRRFSNGEPEDNVKLIVFHAWGGKLLKQYG--------------------------------- 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 180 ilamisLEKNKLNRPKDvkaktpveqEFKEVYERFEEVKQRYnyidfddilletyymlennaplltQLQQRFHYIEVDEF 259
Cdd:COG3972 257 ------IPPLTFSQPNE---------AFDEACKALLEAIQGE------------------------IIPPIYDAILIDEA 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 260 QDTSYAQYEIV-KLLATPRNNLFIAGDDDQAIYGWRGASHqiiLSFPKEFDNTTIiaLNTNYRSNPFIVGLGNEVIKLNQ 338
Cdd:COG3972 298 QDFEPEFLRLLyQLLKPPKKRLIWAYDEAQNIYGRKIPSA---GGIPAGIGRDTI--LKKNYRNTRPILTFAHAFGMGLL 372
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 339 E-----RFDKELYSVREEGVQPFYARPATTLDEANQILQLIQekvdsgdrnYKDfcllyrthsvsrslldqltihkipfi 413
Cdd:COG3972 373 RppgllQGDAEDYEVERPGDKVTLIRPPEPAGRKGPLPEFKK---------YDD-------------------------- 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 414 khgasqsfyehslikpvldhlrlviepfrleslsnilptmyigRDDCISFIERE--QWKYGEGRFPS---LLHFlllnps 488
Cdd:COG3972 418 -------------------------------------------RAEELEAIAEEikKNLRDEGLRPSdiaVIYL------ 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 489 lkpfqvkkvneridFIKFIKELEPKkaLKEIIHGKGKYLEYLQSNDRSSFtmhkdiqeemleelmesatrftdipaylqf 568
Cdd:COG3972 449 --------------GNNEAKELGDR--LAAALERQGIDSYIAGARSDPNF------------------------------ 482
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 569 ideaiqgqkemealktMPQKDAVSLMSIHNAKGLEFPCVFLLGAsDGILPHtsslkdandritetsEALEEERRLLYVAI 648
Cdd:COG3972 483 ----------------FWKDGGVTISTIHRAKGLEAPVVIIVGL-DQLAKG---------------ESLERLRNLLYVAM 530
|
650
....*....|.
gi 446113356 649 TRAKEELYISS 659
Cdd:COG3972 531 TRARGWLVVSG 541
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
55-136 |
2.55e-12 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 64.55 E-value: 2.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 55 QLEAVRT--TEGPVLTLAGAGSGKTSVLTTRVGYLVNVKQVhPRNILLLTFTQKAAEEIRSRvaklpgMNHAASsyvvag 132
Cdd:pfam13245 1 QREAVRTalPSKVVLLTGGPGTGKTTTIRHIVALLVALGGV-SFPILLAAPTGRAAKRLSER------TGLPAS------ 67
|
....
gi 446113356 133 TFHS 136
Cdd:pfam13245 68 TIHR 71
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
594-657 |
6.26e-11 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 57.97 E-value: 6.26e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446113356 594 MSIHNAKGLEFPCVFLLgasDGILPhtsslkdandriteTSEALEEERRLLYVAITRAKEELYI 657
Cdd:pfam13538 5 LTVHKAQGSEFPAVFLV---DPDLT--------------AHYHSMLRRRLLYTAVTRARKKLVL 51
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
208-327 |
6.28e-09 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 59.60 E-value: 6.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 208 KEVYERFEEVKQRYNYIDFDDIL--LETYYMLENNAPLLTQLQQRFHYIEVDEFQDTSYAQYEIVKLL--ATPRNNLFIA 283
Cdd:PRK10876 333 AEIRETVAQEKRRRGELGFDDLLsrLDSALQSEGGEALAAAIRTRYPVAMIDEFQDTDPQQYRIFRRIyrHQPETALLLI 412
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 446113356 284 GDDDQAIYGWRGAShqiILSFPKEFDNTTI-IALNTNYRSNPFIV 327
Cdd:PRK10876 413 GDPKQAIYAFRGAD---IFTYMKARSEVSAhYTLDTNWRSAPGMV 454
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
594-657 |
2.40e-08 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 51.41 E-value: 2.40e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446113356 594 MSIHNAKGLEFPCVFLlgasdgILPHTSSLkdandritetsealeEERRLLYVAITRAKEELYI 657
Cdd:cd18809 36 MTIHKSQGSEFDRVIV------VLPTSHPM---------------LSRGLLYTALTRARKLLTL 78
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
65-113 |
5.24e-08 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 51.72 E-value: 5.24e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446113356 65 PVLTLAGAGSGKTSVLTTRVGYLVNVKQVHPRNILLLTFTQKAAEEIRS 113
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLDN 49
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
588-657 |
1.21e-07 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 49.74 E-value: 1.21e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 588 KDAVSLMSIHNAKGLEFPCVFLLgasdgiLPHTSSLkdandritetsealeeERRLLYVAITRAKEELYI 657
Cdd:cd18786 40 LQLVGAITIDSSQGLTFDVVTLY------LPTANSL----------------TPRRLYVALTRARKRLVI 87
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
250-320 |
2.05e-07 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 50.18 E-value: 2.05e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446113356 250 RFHYIEVDEFQDTSYAQYEIVKLLATPRNNLFIAGDDDQAIYGWRGA-----SHQIILSFPKEFDNTTIIALNTNY 320
Cdd:cd17914 46 QLDNILVDEAAQILEPETSRLIDLALDQGRVILVGDHDQLGPVWRGAvlakiCNEQSLFTRLVRLGVSLIRLQVQY 121
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
594-657 |
2.22e-05 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 47.66 E-value: 2.22e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446113356 594 MSIHNAKGLEFPCVFLLgasdgiLPhtsslkdandriTETSEALEeeRRLLYVAITRAKEELYI 657
Cdd:COG0507 445 ITVHKSQGSTFDRVILV------LP------------SEHSPLLS--RELLYTALTRARELLTL 488
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
591-657 |
2.29e-05 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 47.55 E-value: 2.29e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446113356 591 VSLMSIHNAKGLEFPCVFLLGAsDGILPHTsslkdandritetsealEEERRLLYVAITRAKEELYI 657
Cdd:COG3973 639 VVVLPAYLAKGLEFDAVVVVDP-DEIVYES-----------------PRGRRLLYVALTRATHRLTV 687
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
27-112 |
5.40e-05 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 46.12 E-value: 5.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 27 STHLIMEEDVDAAYFRALEQQNVFLNEKQLEAVRT--TEGPVLTLAG-AGSGKTSVLTtrvgYLVNVKQVHPRNILLLTF 103
Cdd:COG0507 101 ARPALDEADVEAALAALEPRAGITLSDEQREAVALalTTRRVSVLTGgAGTGKTTTLR----ALLAALEALGLRVALAAP 176
|
....*....
gi 446113356 104 TQKAAEEIR 112
Cdd:COG0507 177 TGKAAKRLS 185
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
574-651 |
1.18e-04 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 45.73 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446113356 574 QGQKEMEALKTMPQKDAVSLMSIHNAKGLEFPCVFL-----LGASDGILPHtsslkdanDRIT----------ETSEAL- 637
Cdd:PRK10876 719 DSQASSQQLRLESDKHLVQIVTIHKSKGLEYPLVWLpfitnFRVQDQAFYH--------DRHSfeavldlnaaEESVALa 790
|
90
....*....|....*....
gi 446113356 638 EEER-----RLLYVAITRA 651
Cdd:PRK10876 791 EEERlaedlRLLYVALTRS 809
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
51-118 |
3.08e-03 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 39.47 E-value: 3.08e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446113356 51 LNEKQLEAVR---TTEGPVLTL-AGAGSGKTSVLTTrvgyLVNVKQVHPRNILLLTFTQKAAEEIR-------SRVAKL 118
Cdd:pfam13604 2 LNAEQAAAVRallTSGDRVAVLvGPAGTGKTTALKA----LREAWEAAGYRVIGLAPTGRAAKVLGeelgipaDTIAKL 76
|
|
| |
