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Conserved domains on  [gi|446133850|ref|WP_000211705|]
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MULTISPECIES: class I SAM-dependent methyltransferase [Enterobacteriaceae]

Protein Classification

class I SAM-dependent methyltransferase( domain architecture ID 10789277)

class I SAM-dependent methyltransferase is an enzyme that uses S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyl transfer, creating the product S-adenosyl-L-homocysteine (AdoHcy)

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:0008168|GO:1904047
PubMed:  12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 27-161 4.16e-38

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


:

Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 130.50  E-value: 4.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  27 HASGRDLQRLAV-RLADYPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLkNITTRQGYAESLP 105
Cdd:COG2226    4 VAARYDGREALLaALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAEDLP 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446133850 106 FADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQ 161
Cdd:COG2226   83 FPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDLAELEELLA 138
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 27-161 4.16e-38

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 130.50  E-value: 4.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  27 HASGRDLQRLAV-RLADYPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLkNITTRQGYAESLP 105
Cdd:COG2226    4 VAARYDGREALLaALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAEDLP 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446133850 106 FADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQ 161
Cdd:COG2226   83 FPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDLAELEELLA 138
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 49-145 6.22e-31

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 110.06  E-value: 6.22e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   49 LDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLkniTTRQGYAESLPFADNAFDIVISRYSAHHWHDVGA 128
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGL---TFVVGDAEDLPFPDNSFDLVLSSEVLHHVEDPER 77

                          90
                  ....*....|....*..
gi 446133850  129 ALREVNRILKPGGRLIV 145
Cdd:pfam08241  78 ALREIARVLKPGGILII 94
PRK08317 PRK08317
hypothetical protein; Provisional
 33-227 7.35e-24

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 96.16  E-value: 7.35e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  33 LQRLAVRLADypdaSVLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLDVVAQAAEArQLKNITTRQGYAESLPFADN 109
Cdd:PRK08317  12 FELLAVQPGD----RVLDVGCGPGNDARELARRVGPegrVVGIDRSEAMLALAKERAAG-LGPNVEFVRGDADGLPFPDG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850 110 AFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMD------VMSPGHP--VRDIwlqtVEALRDtsHVRNYASGEWL 181
Cdd:PRK08317  87 SFDAVRSDRVLQHLEDPARALAEIARVLRPGGRVVVLDtdwdtlVWHSGDRalMRKI----LNFWSD--HFADPWLGRRL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446133850 182 -RLINEANLIVDN-----LITDKLPLEFSSWvARMRTPEALVDAIRIYQQSA 227
Cdd:PRK08317 161 pGLFREAGLTDIEvepytLIETDLKEADKGF-GLIRAARRAVEAGGISADEA 211
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 10-163 5.06e-20

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 85.39  E-value: 5.06e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   10 VEKQFSSQASEY-LTSTVHASGRDL---QRLAVRLADYPDASVLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLDVV 82
Cdd:TIGR01934   1 VQEMFDRIAPKYdLLNDLLSFGLHRlwrRRAVKLIGVFKGQKVLDVACGTGDLAIELAKSAPDrgkVTGVDFSSEMLEVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   83 AQAAEARQlkNITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGH----PVRDI 158
Cdd:TIGR01934  81 KKKSELPL--NIEFIQADAEALPFEDNSFDAVTIAFGLRNVTDIQKALREMYRVLKPGGRLVILEFSKPANallkKFYKF 158


                  ....*
gi 446133850  159 WLQTV 163
Cdd:TIGR01934 159 YLKNV 163
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 48-148 2.29e-18

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 77.86  E-value: 2.29e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  48 VLDMGCGAGHASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLPF-ADNAFDIVISRYSAHHWH- 124
Cdd:cd02440    2 VLDLGCGTGALALALASGPGArVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPeADESFDVIISDPPLHHLVe 81

                         90       100
                 ....*....|....*....|....
gi 446133850 125 DVGAALREVNRILKPGGRLIVMDV 148
Cdd:cd02440   82 DLARFLEEARRLLKPGGVLVLTLV 105
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
47-196 7.07e-07

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 48.57  E-value: 7.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850    47 SVLDMGCGAGHASFVAAQNVS--AVVAYDLSAQMLDVVAQAAEARQLKN-ITTRQGYAESLPFADNaFDIVISRYSAHHW 123
Cdd:smart00828   2 RVLDFGCGYGSDLIDLAERHPhlQLHGYTISPEQAEVGRERIRALGLQGrIRIFYRDSAKDPFPDT-YDLVFGFEVIHHI 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446133850   124 HDVGAALREVNRILKPGGRLIVMDVMSPG-----HPVRDIWLQTVEalrdtshvrnyasgEWLRLINEANLIVDNLIT 196
Cdd:smart00828  81 KDKMDLFSNISRHLKDGGHLVLADFIANLlsaieHEETTSYLVTRE--------------EWAELLARNNLRVVEGVD 144
 
Name Accession Description Interval E-value
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 27-161 4.16e-38

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 130.50  E-value: 4.16e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  27 HASGRDLQRLAV-RLADYPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLkNITTRQGYAESLP 105
Cdd:COG2226    4 VAARYDGREALLaALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAEDLP 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446133850 106 FADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQ 161
Cdd:COG2226   83 FPDGSFDLVISSFVLHHLPDPERALAEIARVLKPGGRLVVVDFSPPDLAELEELLA 138
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 49-145 6.22e-31

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 110.06  E-value: 6.22e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   49 LDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLkniTTRQGYAESLPFADNAFDIVISRYSAHHWHDVGA 128
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGL---TFVVGDAEDLPFPDNSFDLVLSSEVLHHVEDPER 77

                          90
                  ....*....|....*..
gi 446133850  129 ALREVNRILKPGGRLIV 145
Cdd:pfam08241  78 ALREIARVLKPGGILII 94
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 48-141 2.03e-28

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 103.80  E-value: 2.03e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   48 VLDMGCGAGHASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEARQLkNITTRQGYAESLPFADNAFDIVISRYSAHHWH-- 124
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGGArVTGVDLSPEMLERARERAAEAGL-NVEFVQGDAEDLPFPDGSFDLVVSSGVLHHLPdp 79

                          90
                  ....*....|....*..
gi 446133850  125 DVGAALREVNRILKPGG 141
Cdd:pfam13649  80 DLEAALREIARVLKPGG 96
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 31-147 6.99e-26

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 98.17  E-value: 6.99e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  31 RDLQRLAVRLADyPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARqlkNITTRQGYAESLPFADNA 110
Cdd:COG2227   12 RRLAALLARLLP-AGGRVLDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAEL---NVDFVQGDLEDLPLEDGS 87

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 446133850 111 FDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMD 147
Cdd:COG2227   88 FDLVICSEVLEHLPDPAALLRELARLLKPGGLLLLST 124
PRK08317 PRK08317
hypothetical protein; Provisional
 33-227 7.35e-24

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 96.16  E-value: 7.35e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  33 LQRLAVRLADypdaSVLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLDVVAQAAEArQLKNITTRQGYAESLPFADN 109
Cdd:PRK08317  12 FELLAVQPGD----RVLDVGCGPGNDARELARRVGPegrVVGIDRSEAMLALAKERAAG-LGPNVEFVRGDADGLPFPDG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850 110 AFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMD------VMSPGHP--VRDIwlqtVEALRDtsHVRNYASGEWL 181
Cdd:PRK08317  87 SFDAVRSDRVLQHLEDPARALAEIARVLRPGGRVVVLDtdwdtlVWHSGDRalMRKI----LNFWSD--HFADPWLGRRL 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446133850 182 -RLINEANLIVDN-----LITDKLPLEFSSWvARMRTPEALVDAIRIYQQSA 227
Cdd:PRK08317 161 pGLFREAGLTDIEvepytLIETDLKEADKGF-GLIRAARRAVEAGGISADEA 211
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 1-163 1.54e-22

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 92.52  E-value: 1.54e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   1 MTTQSHHDHVEKQFSSQASEY-LTSTVHASGRDLQ--RLAVRLAD-YPDASVLDMGCGAGHASFVAAQNVSA---VVAYD 73
Cdd:PRK00216   4 VAEEEKQEKVAEMFDSIAPKYdLMNDLLSFGLHRVwrRKTIKWLGvRPGDKVLDLACGTGDLAIALAKAVGKtgeVVGLD 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  74 LSAQMLDVVAQAAEARQL-KNITTRQGYAESLPFADNAFDIV-ISrYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSP 151
Cdd:PRK00216  84 FSEGMLAVGREKLRDLGLsGNVEFVQGDAEALPFPDNSFDAVtIA-FGLRNVPDIDKALREMYRVLKPGGRLVILEFSKP 162

                        170
                 ....*....|....*.
gi 446133850 152 GHP----VRDIWLQTV 163
Cdd:PRK00216 163 TNPplkkAYDFYLFKV 178
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 44-188 3.93e-20

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 84.01  E-value: 3.93e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   44 PDASVLDMGCGAGHASFVAAQNV---SAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLP--FADNAFDIVISRY 118
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEELgpnAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEELPelLEDDKFDVVISNC 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446133850  119 SAHHWHDVGAALREVNRILKPGGRLIVMDVmspghpvrDIWLQTVEALRDTSHVRN------YASGEWLRLINEAN 188
Cdd:pfam13847  83 VLNHIPDPDKVLQEILRVLKPGGRLIISDP--------DSLAELPAHVKEDSTYYAgcvggaILKKKLYELLEEAG 150
MenG_MenH_UbiE TIGR01934
ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of ...
 10-163 5.06e-20

ubiquinone/menaquinone biosynthesis methyltransferases; This model represents a family of methyltransferases involved in the biosynthesis of menaquinone and ubiqinone. Some members such as the UbiE enzyme from E. coli are believed to act in both pathways, while others may act in only the menaquinone pathway. These methyltransferases are members of the UbiE/CoQ family of methyltransferases (pfam01209) which also contains ubiquinone methyltransferases and other methyltransferases. Members of this clade include a wide distribution of bacteria and eukaryotes, but no archaea. An outgroup for this clade is provided by the phosphatidylethanolamine methyltransferase (EC 2.1.1.17) from Rhodobacter sphaeroides. Note that a number of non-orthologous genes which are members of pfam03737 have been erroneously annotated as MenG methyltransferases. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273884 [Multi-domain]  Cd Length: 223  Bit Score: 85.39  E-value: 5.06e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   10 VEKQFSSQASEY-LTSTVHASGRDL---QRLAVRLADYPDASVLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLDVV 82
Cdd:TIGR01934   1 VQEMFDRIAPKYdLLNDLLSFGLHRlwrRRAVKLIGVFKGQKVLDVACGTGDLAIELAKSAPDrgkVTGVDFSSEMLEVA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   83 AQAAEARQlkNITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGH----PVRDI 158
Cdd:TIGR01934  81 KKKSELPL--NIEFIQADAEALPFEDNSFDAVTIAFGLRNVTDIQKALREMYRVLKPGGRLVILEFSKPANallkKFYKF 158


                  ....*
gi 446133850  159 WLQTV 163
Cdd:TIGR01934 159 YLKNV 163
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 44-151 9.68e-20

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 84.20  E-value: 9.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  44 PDASVLDMGCGAG-HASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQG-YAESLPFADNAFDIVISRYSAH 121
Cdd:COG0500   26 KGGRVLDLGCGTGrNLLALAARFGGRVIGIDLSPEAIALARARAAKAGLGNVEFLVAdLAELDPLPAESFDLVVAFGVLH 105

                         90       100       110
                 ....*....|....*....|....*....|..
gi 446133850 122 HW--HDVGAALREVNRILKPGGRLIVMDVMSP 151
Cdd:COG0500  106 HLppEEREALLRELARALKPGGVLLLSASDAA 137
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 48-148 2.29e-18

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 77.86  E-value: 2.29e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  48 VLDMGCGAGHASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLPF-ADNAFDIVISRYSAHHWH- 124
Cdd:cd02440    2 VLDLGCGTGALALALASGPGArVTGVDISPVALELARKAAAALLADNVEVLKGDAEELPPeADESFDVIISDPPLHHLVe 81

                         90       100
                 ....*....|....*....|....
gi 446133850 125 DVGAALREVNRILKPGGRLIVMDV 148
Cdd:cd02440   82 DLARFLEEARRLLKPGGVLVLTLV 105
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
5-195 8.74e-18

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 78.50  E-value: 8.74e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   5 SHHDHVEKQFSSQASEY---LTSTVH--ASGRDLQRLAVRLADYPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQML 79
Cdd:COG4976    2 ALDAYVEALFDQYADSYdaaLVEDLGyeAPALLAEELLARLPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEML 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  80 DVvaqaAEARQLKnITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVmdvmspghpvrdiw 159
Cdd:COG4976   82 AK----AREKGVY-DRLLVADLADLAEPDGRFDLIVAADVLTYLGDLAAVFAGVARALKPGGLFIF-------------- 142

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 446133850 160 lqTVEALrDTSHVRNYASGEWLRLINEANLIVDNLI 195
Cdd:COG4976  143 --SVEDA-DGSGRYAHSLDYVRDLLAAAGFEVPGLL 175
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
10-154 2.77e-17

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 78.25  E-value: 2.77e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   10 VEKQFSSQASEY------LTSTVHASGRDlqRLAVRLADYPDASVLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLD 80
Cdd:pfam01209   4 VGDVFSSVASKYdlmndvISFGIHRLWKD--FTMKCMGVKRGNKFLDVAGGTGDWTFGLSDSAGSsgkVVGLDINENMLK 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446133850   81 VVAQAAEARQLKNITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHP 154
Cdd:pfam01209  82 EGEKKAKEEGKYNIEFLQGNAEELPFEDDSFDIVTISFGLRNFPDYLKVLKEAFRVLKPGGRVVCLEFSKPENP 155
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 33-145 1.02e-16

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 74.97  E-value: 1.02e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  33 LQRLAVRLADYPDASVLDMGCGAGHASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEARQLKN-ITTRQGYAESLPfADNA 110
Cdd:COG2230   40 LDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVrVTGVTLSPEQLEYARERAAEAGLADrVEVRLADYRDLP-ADGQ 118

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 446133850 111 FDIVISRYSAHH--WHDVGAALREVNRILKPGGRLIV 145
Cdd:COG2230  119 FDAIVSIGMFEHvgPENYPAYFAKVARLLKPGGRLLL 155
arsM PRK11873
arsenite methyltransferase;
48-148 1.22e-16

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 77.30  E-value: 1.22e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  48 VLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLPFADNAFDIVISRYSAHHWH 124
Cdd:PRK11873  81 VLDLGSGGGFDCFLAARRVGPtgkVIGVDMTPEMLAKARANARKAGYTNVEFRLGEIEALPVADNSVDVIISNCVINLSP 160

                         90       100
                 ....*....|....*....|....
gi 446133850 125 DVGAALREVNRILKPGGRLIVMDV 148
Cdd:PRK11873 161 DKERVFKEAFRVLKPGGRFAISDV 184
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
44-145 1.31e-16

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 72.93  E-value: 1.31e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  44 PDASVLDMGCGAGHASFVAAQNVSA--VVAYDLSAQMLdvvaqaAEARQ-LKNITTRQGYAESLPFADNaFDIVISRYSA 120
Cdd:COG4106    1 PPRRVLDLGCGTGRLTALLAERFPGarVTGVDLSPEML------ARARArLPNVRFVVADLRDLDPPEP-FDLVVSNAAL 73

                         90       100
                 ....*....|....*....|....*
gi 446133850 121 HHWHDVGAALREVNRILKPGGRLIV 145
Cdd:COG4106   74 HWLPDHAALLARLAAALAPGGVLAV 98
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 49-143 1.69e-15

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 70.09  E-value: 1.69e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   49 LDMGCGAGHASFVAAQNV--SAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLPFAD-NAFDIVISRYSAHHWHD 125
Cdd:pfam08242   1 LEIGCGTGTLLRALLEALpgLEYTGLDISPAALEAARERLAALGLLNAVRVELFQLDLGELDpGSFDVVVASNVLHHLAD 80

                          90
                  ....*....|....*...
gi 446133850  126 VGAALREVNRILKPGGRL 143
Cdd:pfam08242  81 PRAVLRNIRRLLKPGGVL 98
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 31-189 3.71e-15

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 70.92  E-value: 3.71e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   31 RDLQRLAVRLADYP--DASVLDMGCGAGHASFVAAQNVSAVVAYDLSAqmldvvaqAAEARQLKNITTRQGYAESLPFAD 108
Cdd:pfam13489   7 RLLADLLLRLLPKLpsPGRVLDFGCGTGIFLRLLRAQGFSVTGVDPSP--------IAIERALLNVRFDQFDEQEAAVPA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  109 NAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHpvRDIWLQTVEALRDTS-HVRNYASGEWLRLINEA 187
Cdd:pfam13489  79 GKFDVIVAREVLEHVPDPPALLRQIAALLKPGGLLLLSTPLASDE--ADRLLLEWPYLRPRNgHISLFSARSLKRLLEEA 156


                  ..
gi 446133850  188 NL 189
Cdd:pfam13489 157 GF 158
BioC TIGR02072
malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin ...
 14-211 2.35e-14

malonyl-acyl carrier protein O-methyltransferase BioC; This enzyme, which is found in biotin biosynthetic gene clusters in proteobacteria, firmicutes, green-sulfur bacteria, fusobacterium and bacteroides, carries out an enzymatic step prior to the formation of pimeloyl-CoA, namely O-methylation of the malonyl group preferentially while on acyl carrier protein. The enzyme is recognizable as a methyltransferase by homology. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin]


Pssm-ID: 273953 [Multi-domain]  Cd Length: 240  Bit Score: 70.39  E-value: 2.35e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   14 FSSQASEYltsTVHAsgrDLQR-----LAVRLADYPD---ASVLDMGCGAGHASFVAAQ--NVSAVVAYDLSAQMLdvvA 83
Cdd:TIGR02072   2 FNKAAKTY---DRHA---KIQRemakrLLALLKEKGIfipASVLDIGCGTGYLTRALLKrfPQAEFIALDISAGML---A 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   84 QAAEARQlKNITTRQGYAESLPFADNAFDIVISRySAHHW-HDVGAALREVNRILKPGGRLIVMDVmSPG--HPVRDIWL 160
Cdd:TIGR02072  73 QAKTKLS-ENVQFICGDAEKLPLEDSSFDLIVSN-LALQWcDDLSQALSELARVLKPGGLLAFSTF-GPGtlHELRQSFG 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 446133850  161 QtvealrdtsHVRNYAS-GEWLRLINEANLIVDnLITDKLPLEFSSWVARMR 211
Cdd:TIGR02072 150 Q---------HGLRYLSlDELKALLKNSFELLT-LEEELITLSFDDPLDVLR 191
PRK10258 PRK10258
biotin biosynthesis protein BioC; Provisional
 10-143 2.85e-14

biotin biosynthesis protein BioC; Provisional


Pssm-ID: 182340 [Multi-domain]  Cd Length: 251  Bit Score: 70.17  E-value: 2.85e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  10 VEKQ-----FSSQASEYltsTVHAsgrDLQR-----LAVRLADYPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQML 79
Cdd:PRK10258   4 VNKQaiaaaFGRAAAHY---EQHA---ELQRqsadaLLAMLPQRKFTHVLDAGCGPGWMSRYWRERGSQVTALDLSPPML 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446133850  80 dvvaqaAEARQlKNITTR--QGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRL 143
Cdd:PRK10258  78 ------AQARQ-KDAADHylAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVV 136
PLN02233 PLN02233
ubiquinone biosynthesis methyltransferase
 48-155 2.19e-12

ubiquinone biosynthesis methyltransferase


Pssm-ID: 177877 [Multi-domain]  Cd Length: 261  Bit Score: 64.91  E-value: 2.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  48 VLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLDVVA--QAAEARQ-LKNITTRQGYAESLPFADNAFDIVISRYSAH 121
Cdd:PLN02233  77 VLDLCCGSGDLAFLLSEKVGSdgkVMGLDFSSEQLAVAAsrQELKAKScYKNIEWIEGDATDLPFDDCYFDAITMGYGLR 156

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446133850 122 HWHDVGAALREVNRILKPGGRLIVMDVMSPGHPV 155
Cdd:PLN02233 157 NVVDRLKAMQEMYRVLKPGSRVSILDFNKSTQPF 190
PLN02490 PLN02490
MPBQ/MSBQ methyltransferase
 32-160 2.52e-10

MPBQ/MSBQ methyltransferase


Pssm-ID: 215270 [Multi-domain]  Cd Length: 340  Bit Score: 59.91  E-value: 2.52e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  32 DLQRLAVRLADY--PDASVLDMGCGAGHASFVAAQNVSA--VVAYDLSAQMLdvvAQAAEARQLKNITTRQGYAESLPFA 107
Cdd:PLN02490  99 DMRDDALEPADLsdRNLKVVDVGGGTGFTTLGIVKHVDAknVTILDQSPHQL---AKAKQKEPLKECKIIEGDAEDLPFP 175

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446133850 108 DNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVR----DIWL 160
Cdd:PLN02490 176 TDYADRYVSAGSIEYWPDPQRGIKEAYRVLKIGGKACLIGPVHPTFWLSrffaDVWM 232
PLN02336 PLN02336
phosphoethanolamine N-methyltransferase
 44-154 4.69e-10

phosphoethanolamine N-methyltransferase


Pssm-ID: 177970 [Multi-domain]  Cd Length: 475  Bit Score: 59.38  E-value: 4.69e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  44 PDASVLDMGCGAGHASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEAR------QLKNITTRQgyaeslpFADNAFDIVIS 116
Cdd:PLN02336 266 PGQKVLDVGCGIGGGDFYMAENFDVhVVGIDLSVNMISFALERAIGRkcsvefEVADCTKKT-------YPDNSFDVIYS 338

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 446133850 117 RYSAHHWHDVGAALREVNRILKPGGRLIVMD-VMSPGHP 154
Cdd:PLN02336 339 RDTILHIQDKPALFRSFFKWLKPGGKVLISDyCRSPGTP 377
PRK05785 PRK05785
hypothetical protein; Provisional
 31-136 3.62e-09

hypothetical protein; Provisional


Pssm-ID: 235607 [Multi-domain]  Cd Length: 226  Bit Score: 55.46  E-value: 3.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  31 RDLQRLAVRLADYPdASVLDMGCGAGHASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEarqlknitTRQGYAESLPFADN 109
Cdd:PRK05785  39 AELVKTILKYCGRP-KKVLDVAAGKGELSYHFKKVFKYyVVALDYAENMLKMNLVADD--------KVVGSFEALPFRDK 109

                         90       100
                 ....*....|....*....|....*..
gi 446133850 110 AFDIVISRYSAHHWHDVGAALREVNRI 136
Cdd:PRK05785 110 SFDVVMSSFALHASDNIEKVIAEFTRV 136
COG4627 COG4627
Predicted SAM-depedendent methyltransferase [General function prediction only];
104-145 3.31e-08

Predicted SAM-depedendent methyltransferase [General function prediction only];


Pssm-ID: 443666 [Multi-domain]  Cd Length: 161  Bit Score: 51.79  E-value: 3.31e-08
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 446133850 104 LPFADNAFDIVisrYSAH---H--WHDVGAALREVNRILKPGGRLIV 145
Cdd:COG4627   40 LPFPDNSVDAI---YSSHvleHldYEEAPLALKECYRVLKPGGILRI 83
PLN02244 PLN02244
tocopherol O-methyltransferase
 48-145 6.59e-08

tocopherol O-methyltransferase


Pssm-ID: 215135 [Multi-domain]  Cd Length: 340  Bit Score: 52.44  E-value: 6.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  48 VLDMGCGAGHASFVAAQNVSAVV-AYDLSAqmldvvAQAAEARqlkNITTRQGYAE----------SLPFADNAFDIVIS 116
Cdd:PLN02244 122 IVDVGCGIGGSSRYLARKYGANVkGITLSP------VQAARAN---ALAAAQGLSDkvsfqvadalNQPFEDGQFDLVWS 192

                         90       100
                 ....*....|....*....|....*....
gi 446133850 117 RYSAHHWHDVGAALREVNRILKPGGRLIV 145
Cdd:PLN02244 193 MESGEHMPDKRKFVQELARVAAPGGRIII 221
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 35-146 6.66e-08

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 51.10  E-value: 6.66e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  35 RLAVRLA-DYPDASVLDMGCGAGhaSF-VAAQNVSA-VVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLPFADNAF 111
Cdd:COG1041   16 RALVNLAgAKEGDTVLDPFCGTG--TIlIEAGLLGRrVIGSDIDPKMVEGARENLEHYGYEDADVIRGDARDLPLADESV 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 446133850 112 DIVIS-----RYSAHHWHD----VGAALREVNRILKPGGRLIVM 146
Cdd:COG1041   94 DAIVTdppygRSSKISGEEllelYEKALEEAARVLKPGGRVVIV 137
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 44-145 4.77e-07

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 48.65  E-value: 4.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  44 PDASVLDMGCGAGH-ASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESlPFADNAFDIVIS----R 117
Cdd:COG2813   49 LGGRVLDLGCGYGViGLALAKRNPEArVTLVDVNARAVELARANAAANGLENVEVLWSDGLS-GVPDGSFDLILSnppfH 127

                         90       100
                 ....*....|....*....|....*....
gi 446133850 118 YSAHHWHDVGAAL-REVNRILKPGGRLIV 145
Cdd:COG2813  128 AGRAVDKEVAHALiADAARHLRPGGELWL 156
PKS_MT smart00828
Methyltransferase in polyketide synthase (PKS) enzymes;
47-196 7.07e-07

Methyltransferase in polyketide synthase (PKS) enzymes;


Pssm-ID: 214839 [Multi-domain]  Cd Length: 224  Bit Score: 48.57  E-value: 7.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850    47 SVLDMGCGAGHASFVAAQNVS--AVVAYDLSAQMLDVVAQAAEARQLKN-ITTRQGYAESLPFADNaFDIVISRYSAHHW 123
Cdd:smart00828   2 RVLDFGCGYGSDLIDLAERHPhlQLHGYTISPEQAEVGRERIRALGLQGrIRIFYRDSAKDPFPDT-YDLVFGFEVIHHI 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446133850   124 HDVGAALREVNRILKPGGRLIVMDVMSPG-----HPVRDIWLQTVEalrdtshvrnyasgEWLRLINEANLIVDNLIT 196
Cdd:smart00828  81 KDKMDLFSNISRHLKDGGHLVLADFIANLlsaieHEETTSYLVTRE--------------EWAELLARNNLRVVEGVD 144
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 37-145 3.53e-06

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 46.68  E-value: 3.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  37 AVRLADYPDA----SVLDMGCGAGHASFVAAQNVSA--VVAYDLSAQMldvVAQAAEARQLKNITTR--------QGYAE 102
Cdd:COG4123   26 AVLLAAFAPVkkggRVLDLGTGTGVIALMLAQRSPGarITGVEIQPEA---AELARRNVALNGLEDRitvihgdlKEFAA 102

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446133850 103 slPFADNAFDIVIS-----------------RYSAHH-----WHDVgaaLREVNRILKPGGRLIV 145
Cdd:COG4123  103 --ELPPGSFDLVVSnppyfkagsgrkspdeaRAIARHedaltLEDL---IRAAARLLKPGGRFAL 162
UbiG TIGR01983
ubiquinone biosynthesis O-methyltransferase; This model represents an O-methyltransferase ...
 47-145 3.91e-06

ubiquinone biosynthesis O-methyltransferase; This model represents an O-methyltransferase believed to act at two points in the ubiquinone biosynthetic pathway in bacteria (UbiG) and fungi (COQ3). A separate methylase (MenG/UbiE) catalyzes the single C-methylation step. The most commonly used names for genes in this family do not indicate whether this gene is an O-methyl, or C-methyl transferase. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273910  Cd Length: 224  Bit Score: 46.52  E-value: 3.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   47 SVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLkNITTRQGYAESLPFADN-AFDIVISRYSAHHWHD 125
Cdd:TIGR01983  49 RVLDVGCGGGLLSEPLARLGANVTGIDASEENIEVAKLHAKKDPL-QIDYRCTTVEDLAEKKAgSFDVVTCMEVLEHVPD 127

                          90       100
                  ....*....|....*....|
gi 446133850  126 VGAALREVNRILKPGGRLIV 145
Cdd:TIGR01983 128 PQAFIRACAQLLKPGGILFF 147
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 40-115 6.84e-06

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 45.98  E-value: 6.84e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446133850  40 LADYPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQ-AAEARQLKNITTRQGYAESLpfaDNAFDIVI 115
Cdd:PRK07580  59 DGDLTGLRILDAGCGVGSLSIPLARRGAKVVASDISPQMVEEARErAPEAGLAGNITFEVGDLESL---LGRFDTVV 132
PLN02232 PLN02232
ubiquinone biosynthesis methyltransferase
 73-147 9.87e-06

ubiquinone biosynthesis methyltransferase


Pssm-ID: 165876  Cd Length: 160  Bit Score: 44.68  E-value: 9.87e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446133850  73 DLSAQMLDVVA--QAAEARQ-LKNITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMD 147
Cdd:PLN02232   4 DFSSEQLAVAAtrQSLKARScYKCIEWIEGDAIDLPFDDCEFDAVTMGYGLRNVVDRLRAMKEMYRVLKPGSRVSILD 81
RsmG COG0357
16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) [Translation, ...
 31-146 1.02e-05

16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) [Translation, ribosomal structure and biogenesis]; 16S rRNA G527 N7-methylase RsmG (former glucose-inhibited division protein B) is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440126  Cd Length: 211  Bit Score: 45.14  E-value: 1.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  31 RDLQRLAVR----------LADYPDASVLDMGCGAG-----------HASFVaaqnvsavvaydlsaqMLD-------VV 82
Cdd:COG0357   44 RDPEELWERhildslallpLLPKEGARVLDVGSGAGfpgiplaiarpDLQVT----------------LVDslgkkiaFL 107

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446133850  83 AQAAEARQLKNITTRQGYAESLPfADNAFDIVISR----------YSAHHwhdvgaalrevnriLKPGGRLIVM 146
Cdd:COG0357  108 REVVRELGLKNVTVVHGRAEELA-PREKFDVVTARavaplpdlleLALPL--------------LKPGGRLLAL 166
TrmA COG2265
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ...
 33-115 1.19e-05

tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441866 [Multi-domain]  Cd Length: 377  Bit Score: 45.55  E-value: 1.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  33 LQRLAVRLAD-YPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAE-SLP--FAD 108
Cdd:COG2265  221 LYAAALEWLDlTGGERVLDLYCGVGTFALPLARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEeVLPelLWG 300


                 ....*..
gi 446133850 109 NAFDIVI 115
Cdd:COG2265  301 GRPDVVV 307
Methyltransf_29 pfam03141
Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative ...
 48-141 1.88e-05

Putative S-adenosyl-L-methionine-dependent methyltransferase; This family is a putative S-adenosyl-L-methionine (SAM)-dependent methyltransferase.


Pssm-ID: 335237 [Multi-domain]  Cd Length: 506  Bit Score: 45.37  E-value: 1.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   48 VLDMGCGAghASFVAA---QNVSAvvaydLSAQMLDV-VAQAAEARQ------LKNITTRQgyaesLPFADNAFDIvisr 117
Cdd:pfam03141 121 ALDVGCGV--ASFGAYllsRDVLT-----MSFAPKDVhEAQVQFALErgipamLGVLGTKR-----LPYPSRSFDL---- 184

                          90       100       110
                  ....*....|....*....|....*....|.
gi 446133850  118 ysAH------HWH-DVGAALREVNRILKPGG 141
Cdd:pfam03141 185 --AHcsrcriPWTaNDGILLLEVDRVLRPGG 213
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
37-144 2.37e-05

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 44.26  E-value: 2.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  37 AVRLADYPDASVLDMGCGAGHASFVAAQ-NVSAVVAYDLSAQMLDVVAQAAEARQLK-NITTRQGYAESLPFaDNAFDIV 114
Cdd:COG4076   28 AIERVVKPGDVVLDIGTGSGLLSMLAARaGAKKVYAVEVNPDIAAVARRIIAANGLSdRITVINADATDLDL-PEKADVI 106

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 446133850 115 ISrysahHWHDVG-------AALREVN-RILKPGGRLI 144
Cdd:COG4076  107 IS-----EMLDTAlldegqvPILNHARkRLLKPGGRII 139
PRK11036 PRK11036
tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;
32-146 4.00e-05

tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM;


Pssm-ID: 182918  Cd Length: 255  Bit Score: 43.80  E-value: 4.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  32 DLQRLAVRLADYPdASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQL-KNITTRQGYAESL-PFADN 109
Cdd:PRK11036  33 DLDRLLAELPPRP-LRVLDAGGGEGQTAIKLAELGHQVILCDLSAEMIQRAKQAAEAKGVsDNMQFIHCAAQDIaQHLET 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 446133850 110 AFDIVIsrysahhWHDV-------GAALREVNRILKPGGRLIVM 146
Cdd:PRK11036 112 PVDLIL-------FHAVlewvadpKSVLQTLWSVLRPGGALSLM 148
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 36-145 5.93e-05

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 42.58  E-value: 5.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   36 LAVRLADYPDASVLDMGCGAGH-ASFVAAQNVSA-VVAYDLSAQMLDVVAQAAEARQLKNITTRQ--GYAEslpFADNAF 111
Cdd:pfam05175  23 LLEHLPKDLSGKVLDLGCGAGVlGAALAKESPDAeLTMVDINARALESARENLAANGLENGEVVAsdVYSG---VEDGKF 99

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 446133850  112 DIVISR--YSAHHWHDVGAALREVN---RILKPGGRLIV 145
Cdd:pfam05175 100 DLIISNppFHAGLATTYNVAQRFIAdakRHLRPGGELWI 138
rrmA PRK11088
23S rRNA methyltransferase A; Provisional
 29-152 7.29e-05

23S rRNA methyltransferase A; Provisional


Pssm-ID: 236841 [Multi-domain]  Cd Length: 272  Bit Score: 42.98  E-value: 7.29e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  29 SGRDLQRLAVRLADYPdASVLDMGCGAGHASFVAAQNVSAVVAYDLsaQMLDV--VAQAAEARQLKNITTRQGYAESLPF 106
Cdd:PRK11088  71 RDAVANLLAERLDEKA-TALLDIGCGEGYYTHALADALPEITTMQL--FGLDIskVAIKYAAKRYPQVTFCVASSHRLPF 147

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 446133850 107 ADNAFDIVISRYSAhhwhdvgAALREVNRILKPGGRLIvmdVMSPG 152
Cdd:PRK11088 148 ADQSLDAIIRIYAP-------CKAEELARVVKPGGIVI---TVTPG 183
PRK14968 PRK14968
putative methyltransferase; Provisional
 36-142 9.85e-05

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 42.19  E-value: 9.85e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  36 LAVRLADYPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAqmlDVVAQAAEARQLKNITTR--QGYAESL--PFADNAF 111
Cdd:PRK14968  15 LAENAVDKKGDRVLEVGTGSGIVAIVAAKNGKKVVGVDINP---YAVECAKCNAKLNNIRNNgvEVIRSDLfePFRGDKF 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446133850 112 DIVI--------------SRYSAHHWhDVGAA--------LREVNRILKPGGR 142
Cdd:PRK14968  92 DVILfnppylpteeeeewDDWLNYAL-SGGKDgrevidrfLDEVGRYLKPGGR 143
Methyltransf_8 pfam05148
Hypothetical methyltransferase; This family consists of several uncharacterized eukaryotic ...
 47-173 1.65e-04

Hypothetical methyltransferase; This family consists of several uncharacterized eukaryotic proteins which are related to methyltransferases pfam01209.


Pssm-ID: 398698  Cd Length: 214  Bit Score: 41.73  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   47 SVLDMGCGAGHASFvAAQNVSAVVAYDLSAQMLDVVAqaAEARQLknittrqgyaeslPFADNAFDIVISRYS--AHHWH 124
Cdd:pfam05148  70 VIADLGCGEARIAF-RKREFENVHSFDLVAVNKRVIP--CDMARV-------------PLEDESVDVAVFCLSlmGTNIA 133

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 446133850  125 DVgaaLREVNRILKPGGRLIVMDVMSPGHPVRdIWLQTVEALR-DTSHVR 173
Cdd:pfam05148 134 DF---LKEANRILKNGGLLKIAEVRSRFPSVG-LFERAFTKLGfEVEHVD 179
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 33-163 2.12e-04

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 41.23  E-value: 2.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  33 LQRLAVRladyPDASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAeSLPFADNA-F 111
Cdd:COG2518   59 LEALDLK----PGDRVLEIGTGSGYQAAVLARLAGRVYSVERDPELAERARERLAALGYDNVTVRVGDG-ALGWPEHApF 133

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446133850 112 DIVIsrysahhwhdVGAALREVNRI----LKPGGRLIVmdvmspghPVRDIWLQTV 163
Cdd:COG2518  134 DRII----------VTAAAPEVPEAlleqLAPGGRLVA--------PVGEGGVQRL 171
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 44-184 6.92e-04

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 40.33  E-value: 6.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   44 PDASVLDMGCGAGHASFVAAQ-NVSAVVAYDLSAQMLDVvaqAAEARQLKNITTR-QGYA-ESLPfaDNAFDIVISRYSA 120
Cdd:pfam06325 161 PGESVLDVGCGSGILAIAALKlGAKKVVGVDIDPVAVRA---AKENAELNGVEARlEVYLpGDLP--KEKADVVVANILA 235

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446133850  121 HhwhdvgaALRE----VNRILKPGGRLI-----------VMDVMSPGHPVRDIWLQtvealrdtshvrnyasGEWLRLI 184
Cdd:pfam06325 236 D-------PLIElapdIYALVKPGGYLIlsgilkeqaqmVAEAYSQGFELITVEHR----------------EEWVCIV 291
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
44-145 7.39e-04

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 39.66  E-value: 7.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   44 PDASVLDMGCGAGHASFVAAQNVSA---VVAYDLSAQMLDVVAQAAEARQLKNITT-----RQGYAESLPfadnafdivi 115
Cdd:pfam01135  73 PGMRVLEIGSGSGYLTACFARMVGEvgrVVSIEHIPELVEIARRNLEKLGLENVIVvvgdgRQGWPEFAP---------- 142

                          90       100       110
                  ....*....|....*....|....*....|....
gi 446133850  116 srYSAHHwhdVGAALREVNRI----LKPGGRLIV 145
Cdd:pfam01135 143 --YDAIH---VGAAAPEIPEAlidqLKEGGRLVI 171
Nnt1 COG3897
Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, ...
 34-172 1.24e-03

Protein N-terminal and lysine N-methylase, NNT1/EFM7 family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443104 [Multi-domain]  Cd Length: 216  Bit Score: 39.10  E-value: 1.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  34 QRLAVRLADYPD---ASVLDMGCGAGHASFVAA-QNVSAVVAYDLSAQMLDVVAQAAEARQLKnITTRQGYAESLPfADN 109
Cdd:COG3897   57 QALARYLLDHPEvagKRVLELGCGLGLVGIAAAkAGAADVTATDYDPEALAALRLNAALNGVA-ITTRLGDWRDPP-AAG 134

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446133850 110 AFDIVISR---YSAHHWHDVGAALRevnRILKPGGRLIVMDvmsPGHPVRDIWLQTVEALRDTSHV 172
Cdd:COG3897  135 GFDLILGGdvlYERDLAEPLLPFLD---RLAAPGGEVLIGD---PGRGYLPAFRERLEALAGYEVV 194
Methyltransf_9 pfam08003
Protein of unknown function (DUF1698); This family contains many hypothetical proteins. It ...
 29-152 1.30e-03

Protein of unknown function (DUF1698); This family contains many hypothetical proteins. It also includes two putative methyltransferase proteins, Swiss:Q8EEE6 and Swiss:Q88MX8.


Pssm-ID: 429781 [Multi-domain]  Cd Length: 315  Bit Score: 39.31  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850   29 SGRDLQRLAVRLADYPDASVLDMGCGAGHASF-VAAQNVSAVVAYDLSAQMLdvvAQAAEARQLKNITTRqgyAESLPF- 106
Cdd:pfam08003 100 SDWKWDRVLPHLSPLKGRTILDVGCGNGYHMWrMLGEGAAMVVGIDPSELFL---CQFEAVRKLLGNDQR---AHLLPLg 173

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 446133850  107 -----ADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPG 152
Cdd:pfam08003 174 ieqlpALAAFDTVFSMGVLYHRRSPLDHLLQLKDQLVKGGELVLETLVIDG 224
Rsm22 COG5459
Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal ...
 33-119 1.78e-03

Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) [Translation, ribosomal structure and biogenesis]; Ribosomal protein RSM22 (predicted mitochondrial rRNA methylase) is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 444210 [Multi-domain]  Cd Length: 306  Bit Score: 38.78  E-value: 1.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  33 LQRLAVRLADYPDASVLDMGCGAGHASFVAAQ---NVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESL--PFA 107
Cdd:COG5459   69 LAELAEAGPDFAPLTVLDVGAGPGTAAWAAADawpSLLDATLLERSAAALALGRRLARAAANPALETAEWRLADLaaALP 148

                         90
                 ....*....|..
gi 446133850 108 DNAFDIVISRYS 119
Cdd:COG5459  149 APPADLVVASYV 160
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
42-144 2.62e-03

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 38.21  E-value: 2.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133850  42 DYPDASVLDMGCGAGHASFVAAQ-NVSAVVAYDLSAQMLDVvaqAAEARQLKNITTrqgyAESLPFADNAFDIVIsrysa 120
Cdd:PRK00517 117 VLPGKTVLDVGCGSGILAIAAAKlGAKKVLAVDIDPQAVEA---ARENAELNGVEL----NVYLPQGDLKADVIV----- 184

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446133850 121 hhwhdvgaA--LREV--------NRILKPGGRLI 144
Cdd:PRK00517 185 --------AniLANPllelapdlARLLKPGGRLI 210
PRK11207 PRK11207
tellurite resistance methyltransferase TehB;
46-116 2.81e-03

tellurite resistance methyltransferase TehB;


Pssm-ID: 183040  Cd Length: 197  Bit Score: 37.79  E-value: 2.81e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446133850  46 ASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLPFaDNAFDIVIS 116
Cdd:PRK11207  32 GKTLDLGCGNGRNSLYLAANGFDVTAWDKNPMSIANLERIKAAENLDNLHTAVVDLNNLTF-DGEYDFILS 101
TehB pfam03848
Tellurite resistance protein TehB;
48-116 9.81e-03

Tellurite resistance protein TehB;


Pssm-ID: 397776  Cd Length: 193  Bit Score: 35.98  E-value: 9.81e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446133850   48 VLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEARQLKNITTRQGYAESLPFADNaFDIVIS 116
Cdd:pfam03848  34 VLDLGCGQGRNSLYLSLLGYDVTAWDKNENSIANLQRIKEKENLDNIHTALYDINNATIDEN-YDFILS 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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