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Conserved domains on  [gi|446165527|ref|WP_000243382|]
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MULTISPECIES: BCCT family transporter [Acinetobacter]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
14-520 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 582.10  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  14 RLNRFVFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDHDKPEF 93
Cdd:COG1292   12 KIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDDAKPEF 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  94 GYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEG-EAGTIQAARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDL 172
Cdd:COG1292   92 STFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYFAYRRGL 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 173 PLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITAVLIMMFVATVTT 252
Cdd:COG1292  172 PLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLF-GIPNSLTVQIIIIAVITALFTISA 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 253 VVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFDMYLYNQkaSGWLGSWTVFYWAWWI 332
Cdd:COG1292  251 VSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWTVFYWAWWI 328
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 333 AWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQkQKVLGDMVLSDPALSLFKLLEYLPFNP 412
Cdd:COG1292  329 AWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNG-GGDLAEAVAAGVEAALFALLEQLPLGT 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 413 YIAGIVVVICFVLFLTPVGSGTLMIANLSSKGgtsDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQSAVVLCGLPFSV 492
Cdd:COG1292  408 ILSVLAIILVIIFFVTSADSGSLVLAMLTSGG---DEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPFSF 484
                        490       500
                 ....*....|....*....|....*...
gi 446165527 493 IILLYMFGLAKALKQDDFDPNVAKKQLA 520
Cdd:COG1292  485 VLLLMCVSLVKALREDPRRLRSAEAEAA 512
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
14-520 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 582.10  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  14 RLNRFVFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDHDKPEF 93
Cdd:COG1292   12 KIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDDAKPEF 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  94 GYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEG-EAGTIQAARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDL 172
Cdd:COG1292   92 STFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYFAYRRGL 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 173 PLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITAVLIMMFVATVTT 252
Cdd:COG1292  172 PLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLF-GIPNSLTVQIIIIAVITALFTISA 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 253 VVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFDMYLYNQkaSGWLGSWTVFYWAWWI 332
Cdd:COG1292  251 VSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWTVFYWAWWI 328
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 333 AWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQkQKVLGDMVLSDPALSLFKLLEYLPFNP 412
Cdd:COG1292  329 AWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNG-GGDLAEAVAAGVEAALFALLEQLPLGT 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 413 YIAGIVVVICFVLFLTPVGSGTLMIANLSSKGgtsDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQSAVVLCGLPFSV 492
Cdd:COG1292  408 ILSVLAIILVIIFFVTSADSGSLVLAMLTSGG---DEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPFSF 484
                        490       500
                 ....*....|....*....|....*...
gi 446165527 493 IILLYMFGLAKALKQDDFDPNVAKKQLA 520
Cdd:COG1292  485 VLLLMCVSLVKALREDPRRLRSAEAEAA 512
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
19-508 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 544.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   19 VFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDHDKPEFGYLAW 98
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   99 TSMLFSAGIGIALLYYGVAEPVDHFLR-PPEGEAGTIQAARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDLPLALR 177
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  178 SALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITAVLIMMFVATVTTVVGIE 257
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLF-GIPNTLTTQLAIIAIITALFTISAVSGLD 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  258 KGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFDMYLYNQkASGWLGSWTVFYWAWWIAWAPF 337
Cdd:pfam02028 240 KGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPF 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  338 VGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQkQKVLGDMVLSDPALSLFKLLEYLPFNPYIAGI 417
Cdd:pfam02028 319 VGMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNG-PGDLADAVEAGPPAALFALLEQLPLGTILSVL 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  418 VVVICFVLFLTPVGSGTLMIANLSSKGgtsDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQSAVVLCGLPFSVIILLY 497
Cdd:pfam02028 398 ALLLIIIFFVTSADSGTLVIAMLSSGG---DLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLM 474
                         490
                  ....*....|.
gi 446165527  498 MFGLAKALKQD 508
Cdd:pfam02028 475 CISLFKALREE 485
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-520 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 530.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   1 MVLKSDGYSSDHIRLNRFVFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVG 80
Cdd:PRK09928   1 MVMTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  81 QIPLGKDHDKPEFGYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEGEAGTIQAARNAMTYSFLHWGIHGWVLYALLG 160
Cdd:PRK09928  81 SIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 161 VTLGYFAFRQDLPLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITA 240
Cdd:PRK09928 161 MALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLF-DIPESLAAQAAL 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 241 VLIMMFVATVTTVVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFDMYLYNQkASGWL 320
Cdd:PRK09928 240 IALSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDR-PTEWM 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 321 GSWTVFYWAWWIAWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQKQKvLGDMVLSDPALS 400
Cdd:PRK09928 319 NNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAA-FAEEAMAHPERG 397
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 401 LFKLLEYLPFNPYIAGIVVVICFVLFLTPVGSGTLMIANLSSKGGTSDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQ 480
Cdd:PRK09928 398 FYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQ 477
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|
gi 446165527 481 SAVVLCGLPFSVIILLYMFGLAKALKQDDFDPNVAKKQLA 520
Cdd:PRK09928 478 NTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTA 517
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
57-508 5.49e-143

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 419.84  E-value: 5.49e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   57 GWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDHDKPEFGYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEGEAGTI-Q 135
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTStT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  136 AARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDLPLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIG 215
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  216 ALVLVSGICYLIpEIPDNSATLITAVLIMMFVATVTTVVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNT 295
Cdd:TIGR00842 161 APQINAGLSALF-GIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  296 GDYLNNFMGKSFDMYLYnQKASGWLGSWTVFYWAWWIAWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGN 375
Cdd:TIGR00842 240 GNYLQNFPQMSFRTDPD-DGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGN 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  376 TAIHLILNQKQKVLGDMVLSDPALSLFKLLEYLPFNPYIAGIVVVICFVLFLTPVGSGTLMIANLSSKGGTSDSDSPIWL 455
Cdd:TIGR00842 319 SALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLGEEPPKWV 398
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 446165527  456 RIFWSVVITIVSIGLLLAG-SFNSMQSAVVLCGLPFSVIILLYMFGLAKALKQD 508
Cdd:TIGR00842 399 RVFWAVAIGLIALVLLFSGgSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
14-520 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 582.10  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  14 RLNRFVFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDHDKPEF 93
Cdd:COG1292   12 KIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDDAKPEF 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  94 GYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEG-EAGTIQAARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDL 172
Cdd:COG1292   92 STFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYFAYRRGL 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 173 PLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITAVLIMMFVATVTT 252
Cdd:COG1292  172 PLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLF-GIPNSLTVQIIIIAVITALFTISA 250
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 253 VVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFDMYLYNQkaSGWLGSWTVFYWAWWI 332
Cdd:COG1292  251 VSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGGWTVFYWAWWI 328
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 333 AWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQkQKVLGDMVLSDPALSLFKLLEYLPFNP 412
Cdd:COG1292  329 AWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNG-GGDLAEAVAAGVEAALFALLEQLPLGT 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 413 YIAGIVVVICFVLFLTPVGSGTLMIANLSSKGgtsDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQSAVVLCGLPFSV 492
Cdd:COG1292  408 ILSVLAIILVIIFFVTSADSGSLVLAMLTSGG---DEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPFSF 484
                        490       500
                 ....*....|....*....|....*...
gi 446165527 493 IILLYMFGLAKALKQDDFDPNVAKKQLA 520
Cdd:COG1292  485 VLLLMCVSLVKALREDPRRLRSAEAEAA 512
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
19-508 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 544.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   19 VFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDHDKPEFGYLAW 98
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   99 TSMLFSAGIGIALLYYGVAEPVDHFLR-PPEGEAGTIQAARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDLPLALR 177
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  178 SALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITAVLIMMFVATVTTVVGIE 257
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLF-GIPNTLTTQLAIIAIITALFTISAVSGLD 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  258 KGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFDMYLYNQkASGWLGSWTVFYWAWWIAWAPF 337
Cdd:pfam02028 240 KGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPF 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  338 VGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQkQKVLGDMVLSDPALSLFKLLEYLPFNPYIAGI 417
Cdd:pfam02028 319 VGMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNG-PGDLADAVEAGPPAALFALLEQLPLGTILSVL 397
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  418 VVVICFVLFLTPVGSGTLMIANLSSKGgtsDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQSAVVLCGLPFSVIILLY 497
Cdd:pfam02028 398 ALLLIIIFFVTSADSGTLVIAMLSSGG---DLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLM 474
                         490
                  ....*....|.
gi 446165527  498 MFGLAKALKQD 508
Cdd:pfam02028 475 CISLFKALREE 485
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-520 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 530.04  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   1 MVLKSDGYSSDHIRLNRFVFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVG 80
Cdd:PRK09928   1 MVMTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  81 QIPLGKDHDKPEFGYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEGEAGTIQAARNAMTYSFLHWGIHGWVLYALLG 160
Cdd:PRK09928  81 SIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 161 VTLGYFAFRQDLPLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITA 240
Cdd:PRK09928 161 MALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLF-DIPESLAAQAAL 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 241 VLIMMFVATVTTVVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFDMYLYNQkASGWL 320
Cdd:PRK09928 240 IALSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDR-PTEWM 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 321 GSWTVFYWAWWIAWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQKQKvLGDMVLSDPALS 400
Cdd:PRK09928 319 NNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAA-FAEEAMAHPERG 397
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 401 LFKLLEYLPFNPYIAGIVVVICFVLFLTPVGSGTLMIANLSSKGGTSDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQ 480
Cdd:PRK09928 398 FYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQ 477
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|
gi 446165527 481 SAVVLCGLPFSVIILLYMFGLAKALKQDDFDPNVAKKQLA 520
Cdd:PRK09928 478 NTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTA 517
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
57-508 5.49e-143

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 419.84  E-value: 5.49e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   57 GWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDHDKPEFGYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEGEAGTI-Q 135
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTStT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  136 AARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDLPLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIG 215
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  216 ALVLVSGICYLIpEIPDNSATLITAVLIMMFVATVTTVVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNT 295
Cdd:TIGR00842 161 APQINAGLSALF-GIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  296 GDYLNNFMGKSFDMYLYnQKASGWLGSWTVFYWAWWIAWAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGN 375
Cdd:TIGR00842 240 GNYLQNFPQMSFRTDPD-DGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGN 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  376 TAIHLILNQKQKVLGDMVLSDPALSLFKLLEYLPFNPYIAGIVVVICFVLFLTPVGSGTLMIANLSSKGGTSDSDSPIWL 455
Cdd:TIGR00842 319 SALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLGEEPPKWV 398
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 446165527  456 RIFWSVVITIVSIGLLLAG-SFNSMQSAVVLCGLPFSVIILLYMFGLAKALKQD 508
Cdd:TIGR00842 399 RVFWAVAIGLIALVLLFSGgSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09950 PRK09950
putative transporter; Provisional
9-508 1.97e-65

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 220.82  E-value: 1.97e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527   9 SSDHIRLNRFVFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDh 88
Cdd:PRK09950   2 QNNKKKKDKPLISTSLLAVFFIVAALSLFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLGEG- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  89 dKPEFGYLAWTSMLFSAGIGIALLYYGVAEPVDHFLRPPEGEAG-TIQAARNAMTYSFLHWGIHGWVLYALLGVTLGY-F 166
Cdd:PRK09950  81 -KPEYSTLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPGLNIAPrSPKALEYSVSYSFFHWGISAWATYALASLIMAYhF 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 167 AFRQDLPLALRSALYPIFGERVHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYLIpEIPDNSATLITAVLIMMF 246
Cdd:PRK09950 160 HVRKNKGLSLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALT-GLPNNFTVQAFVILLSGV 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 247 VATVTTVVGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMgksfDMYLYNQKAS--GWLGSWT 324
Cdd:PRK09950 239 IFCLSSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFL----QMSLFTDPMGdgSFTRNWT 314
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 325 VFYWAWWIAWAPFVGMFIARISKGRTIREVVLGVClipLGFTLAWISIFG---NTAIHLILNQKQKVLGDMVLSDPALSL 401
Cdd:PRK09950 315 VFYWLWWISYTPGVAMFVTRVSRGRKIKEVIWGLI---LGSSVGCWFFFGvleSYAIHQFINGVINVPQILNTLGGETAV 391
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 402 FKLLEYLPFNPYIAGIVVVICFVLFLTPVGSGTLMIANLSSKGGTSDSDSPIWLRIFWSVVITIVSIGLLLAG-SFNSMQ 480
Cdd:PRK09950 392 QQLLSSLPAGKLFLAAYLGIMIIFLASHMDAVAYTMAATSTRNLREGDDPDRGLRLFWCVVITLIPLSILFTGaSLDTMK 471
                        490       500
                 ....*....|....*....|....*...
gi 446165527 481 SAVVLCGLPFSVIILLYMFGLAKALKQD 508
Cdd:PRK09950 472 TTVVLTALPFLVILLIKVYGFIRWLKQD 499
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
19-506 1.54e-64

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 218.45  E-value: 1.54e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  19 VFWSSAVSIGIFGLLFVLFPEKSQFWLTYVQEQVNHFFGWYYMLVIVLCLGFVAWLAFSRVGQIPLGKDhdKPEFGYLAW 98
Cdd:PRK03356  14 VFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDE--KPEFSTASW 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527  99 TSMLFSAGIGIALLYYGVAEPVDHFLRPPEG-EAGTIQAARNAMTYSFLHWGIHGWVLYALLGVTLGYFAFRQDLPLALR 177
Cdd:PRK03356  92 IFMMFASCTSAAVLFWGSIEIYYYISTPPFGlEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFVRKMDVIRP 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 178 S-ALYPIFGER-VHGLVGDFVDGFGILATVISLVTNLGIGALVLVSGICYL--IPEIPDNSATLITAVLIMMfvaTVTTV 253
Cdd:PRK03356 172 SsTLVPLVGEKhAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLfgIPHTLQLDAIIITCWIILN---AICVA 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 254 VGIEKGLAWLSRINLRLLYALLLFVFLTGPTNHLLNGLVQNTGDYLNNFMGKSFdmYLYNQKASGWLGSWTVFYWAWWIA 333
Cdd:PRK03356 249 CGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLF--YTDPIGKGGFPQGWTVFYWAWWVI 326
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 334 WAPFVGMFIARISKGRTIREVVLGVCLIPLGFTLAWISIFGNTAIHLILNQKQKVLGDMVLSDPALSLFKLLEYLPFNPY 413
Cdd:PRK03356 327 YAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVARAIIETWAALPLSTA 406
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446165527 414 IAGIVVVICFVLFLTPVGSGTLMIANLSSKGGTSDSDSPIWLRIFWSVVITIVSIGLLLAGSFNSMQSAVVLCGLPFSVI 493
Cdd:PRK03356 407 TMWGFFILCFIATVTLINACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFV 486
                        490
                 ....*....|...
gi 446165527 494 ILLYMFGLAKALK 506
Cdd:PRK03356 487 NIMVTLSFIKDAK 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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