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Conserved domains on  [gi|446190667|ref|WP_000268522|]
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MULTISPECIES: recombination regulator RecX [Bacillus]

Protein Classification

regulatory protein RecX( domain architecture ID 10014591)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-270 3.20e-106

recombination regulator RecX; Provisional


:

Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 308.68  E-value: 3.20e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667   4 ITKIEVQKRSKERFNIYIDkgqgEEYGFSVNEVILIKHGLQKGLEIDEIALGNILYNEEVQKAYLQAISYLSYQMRTKLE 83
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLD----EKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKE 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667  84 IEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIE 163
Cdd:PRK14135  77 VRDYLKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667 164 NALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDEKDDEKQREALHYHGNKYYEKYKKYDGWTFEN 243
Cdd:PRK14135 157 VAQKLAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQ 236
                        250       260
                 ....*....|....*....|....*..
gi 446190667 244 KMKQALYRKGFSIDEIEIFLQMKREEG 270
Cdd:PRK14135 237 KLKQALYRKGFSYDDIDSFLREYGIED 263
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-270 3.20e-106

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 308.68  E-value: 3.20e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667   4 ITKIEVQKRSKERFNIYIDkgqgEEYGFSVNEVILIKHGLQKGLEIDEIALGNILYNEEVQKAYLQAISYLSYQMRTKLE 83
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLD----EKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKE 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667  84 IEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIE 163
Cdd:PRK14135  77 VRDYLKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667 164 NALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDEKDDEKQREALHYHGNKYYEKYKKYDGWTFEN 243
Cdd:PRK14135 157 VAQKLAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQ 236
                        250       260
                 ....*....|....*....|....*..
gi 446190667 244 KMKQALYRKGFSIDEIEIFLQMKREEG 270
Cdd:PRK14135 237 KLKQALYRKGFSYDDIDSFLREYGIED 263
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
61-212 6.31e-36

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 125.29  E-value: 6.31e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667  61 EEVQKAYLQAISYLSYQMRTKLEIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELL 140
Cdd:COG2137    3 DTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQELR 82
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446190667 141 NKGVQDLIITHSLQEYPKEKQIENALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDE 212
Cdd:COG2137   83 QKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLEE 154
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
88-208 8.31e-24

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 93.04  E-value: 8.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667   88 LRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIenALI 167
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 446190667  168 LIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEE 208
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQE 119
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-270 3.20e-106

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 308.68  E-value: 3.20e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667   4 ITKIEVQKRSKERFNIYIDkgqgEEYGFSVNEVILIKHGLQKGLEIDEIALGNILYNEEVQKAYLQAISYLSYQMRTKLE 83
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLD----EKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKE 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667  84 IEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIE 163
Cdd:PRK14135  77 VRDYLKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667 164 NALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDEKDDEKQREALHYHGNKYYEKYKKYDGWTFEN 243
Cdd:PRK14135 157 VAQKLAEKLLKKYQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYSKYDGYELKQ 236
                        250       260
                 ....*....|....*....|....*..
gi 446190667 244 KMKQALYRKGFSIDEIEIFLQMKREEG 270
Cdd:PRK14135 237 KLKQALYRKGFSYDDIDSFLREYGIED 263
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
61-212 6.31e-36

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 125.29  E-value: 6.31e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667  61 EEVQKAYLQAISYLSYQMRTKLEIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELL 140
Cdd:COG2137    3 DTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQELR 82
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446190667 141 NKGVQDLIITHSLQEYPKEKQIENALILIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEELKDE 212
Cdd:COG2137   83 QKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELLEE 154
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
88-208 8.31e-24

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 93.04  E-value: 8.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667   88 LRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQIenALI 167
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 446190667  168 LIEKKKKSYQKHSFLQMKLKLDEMLVRKGYSRDVIQICLEE 208
Cdd:pfam02631  79 LAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQE 119
recX PRK14134
recombination regulator RecX; Provisional
3-227 4.54e-20

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 87.17  E-value: 4.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667   3 VITKIEVQKRSKERFNIYIDkgqgEEYGFSVNEVILIKHGLQKGLEIDEIALGNILYNEEVQKAYLQAISYLSYQMRTKL 82
Cdd:PRK14134   4 IITKIEVQKRNKDRVNVYID----EEFAFACSAELVYYHNLKKGKVIDVNSLNDIIKEDNYIKCKGYALKYIEKSYKTEK 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667  83 EIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRtqSNVNRKGPTVIKRELLNKGVQDLIITHSLQEYPKEKQI 162
Cdd:PRK14134  80 QIKEKLYLKEYDEDAVNRVIRFLKEYNFIDDDKYCDMYIR--EKINSYGRNKIKYTLLNKGIKENIIIEKINNIDEEKEK 157
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446190667 163 ENALILIEKKKKSYQKHSFLQMKL--KLDEMLVRKGYSRDVIQICLEELKDEKDDEKQREALHYHGN 227
Cdd:PRK14134 158 KVAYKLAEKKYKILILSEKNKFKIykKLGPYLISRGYSSNIAEWILNELIKNEALYKDNNSQNIENN 224
recX PRK00117
recombination regulator RecX; Reviewed
70-212 3.84e-18

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 79.16  E-value: 3.84e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446190667  70 AISYLSYQMRTKLEIEDFLRKKEVGQAIISEVVSKLLHDRYINDKEYAILYTRTQSNvNRKGPTVIKRELLNKGVQDLII 149
Cdd:PRK00117  17 ALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRAR-KGYGPRRIRQELRQKGVDREII 95
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446190667 150 THSLQEYPKEkQIENALILIEKKKKSYQKHSFlQMKLKLDEMLVRKGYSRDVIQICLEELKDE 212
Cdd:PRK00117  96 EEALAELDID-WEELARELARKKFRRPLPDDA-KEKAKLVRFLARRGFSMDVIQRVLRNALDD 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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