NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|446197680|ref|WP_000275535|]
View 

MULTISPECIES: tagatose bisphosphate family class II aldolase [Enterobacteriaceae]

Protein Classification

tagatose-bisphosphate aldolase subunit GatY( domain architecture ID 10793695)

tagatose-bisphosphate aldolase subunit GatY is the catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP)

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
1-284 0e+00

tagatose-bisphosphate aldolase subunit GatY;


:

Pssm-ID: 183710  Cd Length: 284  Bit Score: 562.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK12737   1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGTDYIVAIAEVAARKYNIPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAA 160
Cdd:PRK12737  81 LDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKDAMYTNPDAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK12737 161 AEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFS 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446197680 241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK12737 241 DAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
 
Name Accession Description Interval E-value
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
1-284 0e+00

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 562.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK12737   1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGTDYIVAIAEVAARKYNIPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAA 160
Cdd:PRK12737  81 LDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKDAMYTNPDAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK12737 161 AEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFS 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446197680 241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK12737 241 DAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
tag_bisphos_ald TIGR01858
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1, ...
 3-284 9.64e-165

class II aldolase, tagatose bisphosphate family; This model describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4.


Pssm-ID: 130917  Cd Length: 282  Bit Score: 458.17  E-value: 9.64e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680    3 IISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLD 82
Cdd:TIGR01858   1 IVSTKYMLQDAQAGGYAVPAFNIHNLETIQAVVETAAEMRSPVILAGTPGTFKHAGTEYIVALCSAASTTYNMPLALHLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   83 HHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAAAE 162
Cdd:TIGR01858  81 HHESLDDIRQKVHAGVRSAMIDGSHFPFAQNVKLVKEVVDFCHRQDCSVEAELGRLGGVEDDLSVDEEDALYTDPQEAKE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  163 FVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADA 242
Cdd:TIGR01858 161 FVEATGVDSLAVAIGTAHGLYKKTPKLDFDRLAEIREVVDVPLVLHGASDVPDEDVRRTIELGICKVNVATELKIAFSGA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 446197680  243 LKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:TIGR01858 241 VKAYFAENPQANDPRYYMRPGKDAMKKVVRNKINVCGSAGRA 282
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 3-283 1.44e-143

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 404.47  E-value: 1.44e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   3 IISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLD 82
Cdd:COG0191    2 LVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYLAAMVRAAAEEASVPVALHLD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  83 HHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAAAE 162
Cdd:COG0191   82 HGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDDAEALYTDPEEAAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 163 FVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADA 242
Cdd:COG0191  162 FVEETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAA 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 446197680 243 LKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:COG0191  242 VREYLAENPDKYDPRKYLKPAREAMKEVVKEKIRLFGSAGK 282
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
4-283 1.16e-133

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 379.06  E-value: 1.16e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680    4 ISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRY--GGVGSLISLVQSLAREYNLPLVLHL 81
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKyaGGAEALAALVRAAAEAAGVPVALHL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   82 DHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKdsAYTSPAAAA 161
Cdd:pfam01116  81 DHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEK--LYTDPEEAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  162 EFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFAD 241
Cdd:pfam01116 159 EFVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTA 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 446197680  242 ALKgyfyNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:pfam01116 239 AVR----EYPPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 7-282 6.38e-129

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 367.24  E-value: 6.38e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   7 KNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLDHHEE 86
Cdd:cd00947    2 KELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELLVAMVKAAAERASVPVALHLDHGSS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  87 SDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEkdSAYTSPAAAAEFVQR 166
Cdd:cd00947   82 FELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDE--GLLTDPEEAEEFVEE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 167 TQIDSLAVAIGTAHGLY-AHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADALKG 245
Cdd:cd00947  160 TGVDALAVAIGTSHGAYkGGEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALRE 239

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 446197680 246 YFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEG 282
Cdd:cd00947  240 YLAENPKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
 
Name Accession Description Interval E-value
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
1-284 0e+00

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 562.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK12737   1 MYIISTKNMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAGTDYIVAIAEVAARKYNIPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAA 160
Cdd:PRK12737  81 LDHHEDLDDIKKKVRAGIRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQEDDLVVDEKDAMYTNPDAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK12737 161 AEFVERTGIDSLAVAIGTAHGLYKGEPKLDFERLAEIREKVSIPLVLHGASGVPDEDVKKAISLGICKVNVATELKIAFS 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446197680 241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK12737 241 DAVKKYFYENPKANDPRKYMTPGKAAMKEVVREKIKVCGSEGKL 284
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 1-284 0e+00

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 520.07  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK09195   1 MYLVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFSYAGTEYLLAIVSAAAKQYHHPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAA 160
Cdd:PRK09195  81 LDHHEKFDDIAQKVRSGVRSVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLGGQEDDLQVDEADALYTDPAQA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK09195 161 REFVEATGIDSLAVAIGTAHGMYKGEPKLDFDRLENIRQWVNIPLVLHGASGLPTKDIQQTIKLGICKVNVATELKIAFS 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446197680 241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK09195 241 QALKNYLTEHPEANDPRHYLQPAKSAMKDVVSKVIADCGCEGKA 284
tag_bisphos_ald TIGR01858
class II aldolase, tagatose bisphosphate family; This model describes tagatose-1, ...
 3-284 9.64e-165

class II aldolase, tagatose bisphosphate family; This model describes tagatose-1,6-bisphosphate aldolases, and perhaps other closely related class II aldolases. This tetrameric, Zn2+-dependent enzyme is related to the class II fructose bisphosphate aldolase; fructose 1,6-bisphosphate and tagatose 1,6 bisphosphate differ only in chirality at C4.


Pssm-ID: 130917  Cd Length: 282  Bit Score: 458.17  E-value: 9.64e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680    3 IISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLD 82
Cdd:TIGR01858   1 IVSTKYMLQDAQAGGYAVPAFNIHNLETIQAVVETAAEMRSPVILAGTPGTFKHAGTEYIVALCSAASTTYNMPLALHLD 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   83 HHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAAAE 162
Cdd:TIGR01858  81 HHESLDDIRQKVHAGVRSAMIDGSHFPFAQNVKLVKEVVDFCHRQDCSVEAELGRLGGVEDDLSVDEEDALYTDPQEAKE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  163 FVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADA 242
Cdd:TIGR01858 161 FVEATGVDSLAVAIGTAHGLYKKTPKLDFDRLAEIREVVDVPLVLHGASDVPDEDVRRTIELGICKVNVATELKIAFSGA 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 446197680  243 LKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:TIGR01858 241 VKAYFAENPQANDPRYYMRPGKDAMKKVVRNKINVCGSAGRA 282
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 3-283 1.44e-143

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 404.47  E-value: 1.44e-143
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   3 IISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLD 82
Cdd:COG0191    2 LVSLKELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAGLEYLAAMVRAAAEEASVPVALHLD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  83 HHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAAAE 162
Cdd:COG0191   82 HGASFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVGGEEDGVDVDDAEALYTDPEEAAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 163 FVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADA 242
Cdd:COG0191  162 FVEETGVDALAVAIGTVHGVYKGEPKLDFDRLKEIREAVPVPLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAA 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 446197680 243 LKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:COG0191  242 VREYLAENPDKYDPRKYLKPAREAMKEVVKEKIRLFGSAGK 282
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
1-284 1.91e-134

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 381.69  E-value: 1.91e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK12738   1 MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAA 160
Cdd:PRK12738  81 LDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK12738 161 KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFA 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446197680 241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK12738 241 GAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRI 284
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
4-283 1.16e-133

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 379.06  E-value: 1.16e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680    4 ISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRY--GGVGSLISLVQSLAREYNLPLVLHL 81
Cdd:pfam01116   1 VNLKELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKyaGGAEALAALVRAAAEAAGVPVALHL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   82 DHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKdsAYTSPAAAA 161
Cdd:pfam01116  81 DHGASFELIKEAIEAGFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIGGEEDGVVVDEK--LYTDPEEAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  162 EFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFAD 241
Cdd:pfam01116 159 EFVEATGVDALAVAIGNVHGVYKPGPKLDFDRLKEIQEAVPVPLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTA 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 446197680  242 ALKgyfyNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:pfam01116 239 AVR----EYPPNKDPRKYLRPAEEAMKEVVKEKIRLFGSAGK 276
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 7-282 6.38e-129

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 367.24  E-value: 6.38e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   7 KNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLDHHEE 86
Cdd:cd00947    2 KELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLELLVAMVKAAAERASVPVALHLDHGSS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  87 SDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEkdSAYTSPAAAAEFVQR 166
Cdd:cd00947   82 FELIKRAIRAGFSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDGVVGDE--GLLTDPEEAEEFVEE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 167 TQIDSLAVAIGTAHGLY-AHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADALKG 245
Cdd:cd00947  160 TGVDALAVAIGTSHGAYkGGEPKLDFDRLKEIAERVNVPLVLHGGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALRE 239

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 446197680 246 YFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEG 282
Cdd:cd00947  240 YLAENPKEFDPRKYLAPAIEAVKEVVKHKMELFGSAG 276
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 1-284 5.57e-128

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 365.49  E-value: 5.57e-128
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680    1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRY-GGVGSLISLVQSL--AREYNLPL 77
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYiAGLGAISAMVKAMseAYPYGVPV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   78 VLHLDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSP 157
Cdd:TIGR00167  81 ALHLDHGASEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVEAELGTLGGEEDGVSVADESALYTDP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  158 AAAAEFVQRTQIDSLAVAIGTAHGLYAHEP-RLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELK 236
Cdd:TIGR00167 161 EEAKEFVKLTGVDSLAAAIGNVHGVYKGEPkGLDFERLEEIQKYVNLPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQ 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 446197680  237 IAFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:TIGR00167 241 IAFAAAVRNYYAENKDYYDPRVWLRPGEKAMKEVVLEKIKLFGSANKA 288
fruc_bis_ald_ TIGR01859
fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; ...
 3-284 8.50e-106

fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; This model represents of one of several subtypes of the class II fructose-1,6-bisphosphate aldolase, an enzyme of glycolysis. The subtypes are split into several models to allow separation of a family of tagatose bisphosphate aldolases. This form is found in Gram-positive bacteria, a variety of Gram-negative, and in amitochondriate protists. The class II enzymes share homology with tagatose bisphosphate aldolase but not with class I aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130918  Cd Length: 282  Bit Score: 308.91  E-value: 8.50e-106
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680    3 IISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRY-GGVGSLISLVQSLAREYN-LPLVLH 80
Cdd:TIGR01859   1 LVNGKEILQKAKKEGYAVGAFNFNNLEWTQAILEAAEEENSPVIIQVSEGAIKYmGGYKMAVAMVKTLIERMSiVPVALH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDllVDEKDSAYTSPAAA 160
Cdd:TIGR01859  81 LDHGSSYESCIKAIKAGFSSVMIDGSHLPFEENLALTKKVVEIAHAKGVSVEAELGTLGGIEDG--VDEKEAELADPDEA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:TIGR01859 159 EQFVKETGVDYLAAAIGTSHGKYKGEPGLDFERLKEIKELTNIPLVLHGASGIPEEQIKKAIKLGIAKINIDTDCRIAFT 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....
gi 446197680  241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:TIGR01859 239 AAIRKVLTEKKDEYDPRKILGPAREAIKETVKEKMRLFGSAGKA 282
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
1-284 6.31e-105

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 306.65  E-value: 6.31e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK12857   1 MMLVTVAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQGAIKYAGIEYISAMVRTAAEKASVPVALH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAA 160
Cdd:PRK12857  81 LDHGTDFEQVMKCIRNGFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAELGKIGGTEDDITVDEREAAMTDPEEA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK12857 161 RRFVEETGVDALAIAIGTAHGPYKGEPKLDFDRLAKIKELVNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNIREAFV 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446197680 241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK12857 241 ARLREVLEKNPDEIDPRKILGPAREAAKEVIREKIRLFGSAGKA 284
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 7-280 8.94e-85

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 257.43  E-value: 8.94e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   7 KNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTP-GTYRYGGVG---------------SLISLVQSLA 70
Cdd:cd00453    2 QKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNgGASFIAGKGvksdvpqgaailgaiSGAHHVHQMA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  71 REYNLPLVLHLDHHEES--DDIFNKVRAG-----------IRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGR 137
Cdd:cd00453   82 EHYGVPVILHTDHCAKKllPWIDGLLDAGekhfaatgkplFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELGC 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 138 LGGQEDDLLVDEKDSA--YTSPAAAAEFVQRT----QIDSLAVAIGTAHGLYA-HEPRLDFVRLEQIRQRV--------- 201
Cdd:cd00453  162 TGGEEDGVDNSHMDASalYTQPEDVDYAYTELskisPRFTIAASFGNVHGVYKkGNVVLTPTILRDSQEYVskkhnlphn 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 202 EIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADALKGYFYNNPAA------------------NDPRHYMQPA 263
Cdd:cd00453  242 SLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYlqgqlgnpkgedqpnkkyYDPRVWLRAG 321

                        330
                 ....*....|....*..
gi 446197680 264 KAAMKEVVTRIIGVCGS 280
Cdd:cd00453  322 QTSMIARLEKAFQELNA 338
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 1-283 1.59e-82

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 249.90  E-value: 1.59e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRY-GGVGSLISLVQSLAREYNL--PL 77
Cdd:PRK08610   1 MPLVSMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYmSGFYTVVKMVEGLMHDLNItiPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  78 VLHLDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDekDSAYTSP 157
Cdd:PRK08610  81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVAD--GIIYADP 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 158 AAAAEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKI 237
Cdd:PRK08610 159 KECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQI 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 446197680 238 AFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:PRK08610 239 ASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNR 284
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
3-284 1.23e-80

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 245.65  E-value: 1.23e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   3 IISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREY-NLPLVLHL 81
Cdd:PRK05835   2 LVKGNEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMGIDMAVGMVKIMCERYpHIPVALHL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  82 DHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAAA 161
Cdd:PRK05835  82 DHGTTFESCEKAVKAGFTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGRLMGIEDNISVDEKDAVLVNPKEAE 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 162 EFVQRTQIDSLAVAIGTAHGLYAH--EPRLDFVRLEQIRQRVEIPLVLHGAS---------------------GLSEQDV 218
Cdd:PRK05835 162 QFVKESQVDYLAPAIGTSHGAFKFkgEPKLDFERLQEVKRLTNIPLVLHGASaipddvrksyldaggdlkgskGVPFEFL 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446197680 219 QHCIRRGICKVNVATELKIAFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK05835 242 QESVKGGINKVNTDTDLRIAFIAEVRKVANEDKSQFDLRKFFSPAQLALKNVVKERMKLLGSANKI 307
PRK08185 PRK08185
hypothetical protein; Provisional
 7-283 1.39e-78

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 239.63  E-value: 1.39e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   7 KNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGvGSLISLVQSLAREYNLPLVLHLDHHEE 86
Cdd:PRK08185   2 KELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDFLG-DNFFAYVRERAKRSPVPFVIHLDHGAT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  87 SDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAAAEFVQR 166
Cdd:PRK08185  81 IEDVMRAIRCGFTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGTIGNTGTSIEGGVSEIIYTDPEQAEDFVSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 167 TQIDSLAVAIGTAHGLYAH--EPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADALK 244
Cdd:PRK08185 161 TGVDTLAVAIGTAHGIYPKdkKPELQMDLLKEINERVDIPLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFFKKVR 240

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 446197680 245 GYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:PRK08185 241 EILSDNPSLYEPNQIYPSAIEAAKEVVRHKMDLFNSTGK 279
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 1-283 8.10e-77

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 235.33  E-value: 8.10e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRY-GGVGSLISLVQSLAREYNL--PL 77
Cdd:PRK07709   1 MPLVSMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHmTGFKTVVAMVKALIEEMNItvPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  78 VLHLDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDekDSAYTSP 157
Cdd:PRK07709  81 AIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAE--GVIYADP 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 158 AAAAEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKI 237
Cdd:PRK07709 159 AECKHLVEATGIDCLAPALGSVHGPYKGEPNLGFAEMEQVRDFTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQI 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 446197680 238 AFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:PRK07709 239 EFTKAVREVLNKDQEVYDPRKFIGPGRDAIKATVIGKIREFGSNGK 284
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
3-284 2.44e-73

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 227.69  E-value: 2.44e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   3 IISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQ---SLARE--YNLPL 77
Cdd:PRK07084   9 LVNTREMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVSKGARKYANATLLRYMAQgavEYAKElgCPIPI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  78 VLHLDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDllVDEKDSAYTSP 157
Cdd:PRK07084  89 VLHLDHGDSFELCKDCIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDE--VSAEHHTYTQP 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 158 AAAAEFVQRTQIDSLAVAIGTAHGLYAHEP-------RLDFvrLEQIRQRVE-IPLVLHGAS------------------ 211
Cdd:PRK07084 167 EEVEDFVKKTGVDSLAISIGTSHGAYKFKPgqcppplRFDI--LEEIEKRIPgFPIVLHGSSsvpqeyvktineyggklk 244

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446197680 212 ---GLSEQDVQHCIRRGICKVNVATELKIAFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVT-RIIGVCGSEGKI 284
Cdd:PRK07084 245 daiGIPEEQLRKAAKSAVCKINIDSDGRLAMTAAIRKVFDEKPEEFDPRKYLGPARDELKKLYKhKIINVLGSNGKA 321
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
1-284 2.92e-73

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 226.17  E-value: 2.92e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK06801   1 MALISLANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAEVHFKYISLESLVEAVKFEAARHDIPVVLN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSA-YTSPAA 159
Cdd:PRK06801  81 LDHGLHFEAVVRALRLGFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGEADSAkFTDPQL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 160 AAEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAF 239
Cdd:PRK06801 161 ARDFVDRTGIDALAVAIGNAHGKYKGEPKLDFARLAAIHQQTGLPLVLHGGSGISDADFRRAIELGIHKINFYTGMSQAA 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 446197680 240 ADALKGYFYN-NPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGKI 284
Cdd:PRK06801 241 LAAVEQRMTHrHAIYDEFAELLLGIEEAISDTVAQQMRIFGSAGQA 286
gatY PRK07998
class II aldolase;
1-275 6.88e-70

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 217.32  E-value: 6.88e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK07998   1 MPLVNGRILLDRIQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDlLVDEKDsAYTSPAAA 160
Cdd:PRK07998  81 LDHGKTFEDVKQAVRAGFTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDD-HVSEAD-CKTEPEKV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLyAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK07998 159 KDFVERTGCDMLAVSIGNVHGL-EDIPRIDIPLLKRIAEVSPVPLVIHGGSGIPPEILRSFVNYKVAKVNIASDLRKAFI 237

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 446197680 241 DALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRII 275
Cdd:PRK07998 238 TTVGKAYVNNHNEANLARVMAKAKQAVEEDVYSKI 272
PLN02858 PLN02858
fructose-bisphosphate aldolase
 5-283 9.03e-68

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 228.20  E-value: 9.03e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680    5 SSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVgSLISLVQSLAREYNLPLVLHLDHH 84
Cdd:PLN02858 1101 STKELLLNAEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPGALKQGGI-PLVSCCIAAAEQASVPITVHFDHG 1179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   85 EESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAAAEFV 164
Cdd:PLN02858 1180 TSKHELLEALELGFDSVMVDGSHLSFTENISYTKSISSLAHSKGLMVEAELGRLSGTEDGLTVEEYEAKLTDVDQAKEFI 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  165 QRTQIDSLAVAIGTAHGLY-AHEPRLDFVRLEQIRQ---RVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PLN02858 1260 DETGIDALAVCIGNVHGKYpASGPNLRLDLLKELRAlssKKGVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRTAYM 1339

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 446197680  241 DALkgyfyNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:PLN02858 1340 EAL-----SSPKKTDLIDVMSAAKEAMKAVVAEKLRLFGSAGK 1377
PRK06806 PRK06806
class II aldolase;
1-251 1.14e-67

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 211.54  E-value: 1.14e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLH 80
Cdd:PRK06806   1 MPLVQMKELLKKANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAEVRLNHSPLHLIGPLMVAAAKQAKVPVAVH 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  81 LDHHEESDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLlvDEKDSAYTSPAAA 160
Cdd:PRK06806  81 FDHGMTFEKIKEALEIGFTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGS--EDIEMLLTSTTEA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 161 AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQRVEIPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFA 240
Cdd:PRK06806 159 KRFAEETDVDALAVAIGNAHGMYNGDPNLRFDRLQEINDVVHIPLVLHGGSGISPEDFKKCIQHGIRKINVATATFNSVI 238

                        250
                 ....*....|.
gi 446197680 241 DALKGYFYNNP 251
Cdd:PRK06806 239 TAVNNLVLNTP 249
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
1-284 5.24e-63

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 201.72  E-value: 5.24e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREY-NLPLVL 79
Cdd:PRK09196   1 MALISLRQLLDHAAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQASAGARKYAGEPFLRHLILAAVEEYpHIPVVM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  80 HLDHHEESDDIFNKVRAGIRSVMIDGSHLP-------FEDNIARVQEVTTFCHRFDVSVEAELGRLG-------GQEDDL 145
Cdd:PRK09196  81 HQDHGNSPATCQRAIQLGFTSVMMDGSLKAdgktpasYEYNVDVTRKVVEMAHACGVSVEGELGCLGsletgmgGEEDGH 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 146 LVDEK---DSAYTSPAAAAEFVQRTQIDSLAVAIGTAHGLY--AHEPRLDFV---RLEQIRQRveIP---LVLHGAS--- 211
Cdd:PRK09196 161 GAEGKlshDQLLTDPEEAADFVKKTQVDALAIAIGTSHGAYkfTRKPTGDVLaidRIKEIHAR--LPnthLVMHGSSsvp 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 212 ------------------GLSEQDVQHCIRRGICKVNVATELKIAFADALKGYFYNNPAANDPRHYMQPAKAAMKEV-VT 272
Cdd:PRK09196 239 qelldiineyggdmpetyGVPVEEIQEGIKHGVRKVNIDTDLRLAMTGAIRRFLAENPSEFDPRKYLKPAMEAMKKIcKA 318

                        330
                 ....*....|....
gi 446197680 273 RII--GVCGSEGKI 284
Cdd:PRK09196 319 RYEafGTAGQASKI 332
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
1-284 7.17e-57

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 186.14  E-value: 7.17e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRYGGVGSLISLVQSLAREY-NLPLVL 79
Cdd:PRK13399   1 MALITLRQLLDHAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYAGDAMLRHMVLAAAEMYpDIPICL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  80 HLDHHEESDDIFNKVRAGIRSVMIDGSHLP-------FEDNIARVQEVTTFCHRFDVSVEAELGRLG-------GQEDDL 145
Cdd:PRK13399  81 HQDHGNSPATCQSAIRSGFTSVMMDGSLLAdgktpasYDYNVDVTRRVTEMAHAVGVSVEGELGCLGsletgeaGEEDGV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 146 LVDEK---DSAYTSPAAAAEFVQRTQIDSLAVAIGTAHGLY--AHEPRLDFVRLEQIRQ-RVEIP---LVLHGAS----- 211
Cdd:PRK13399 161 GAEGKlshDQMLTDPDQAVDFVQRTGVDALAIAIGTSHGAYkfTRKPDGDILAIDRIEEiHARLPnthLVMHGSSsvpqe 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 212 ----------------GLSEQDVQHCIRRGICKVNVATELKIAFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVT--- 272
Cdd:PRK13399 241 lqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRLAMTGAIRKVLAEHPSEFDPRKALKPAMKAMTALCKqrf 320

                        330
                 ....*....|..
gi 446197680 273 RIIGVCGSEGKI 284
Cdd:PRK13399 321 EAFGTAGQASKI 332
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 1-283 8.70e-55

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 178.93  E-value: 8.70e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   1 MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLAGTPGTYRY-GGVGSLISLVQSLAREYNL--PL 77
Cdd:PRK07315   1 MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYmGGYKVCKNLIENLVESMGItvPV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  78 VLHLDHHEeSDDIFNKVRAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLGGQEDDLLvdekDSAYTSP 157
Cdd:PRK07315  81 AIHLDHGH-YEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGII----GKGELAP 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 158 AAAAEFVQRTQIDSLAVAIGTAHGLY-AHEPRLDFVRLEQIRQRVE-IPLVLHGASGLSEQDVQHCIRRGICKVNVATEL 235
Cdd:PRK07315 156 IEDAKAMVETGIDFLAAGIGNIHGPYpENWEGLDLDHLEKLTEAVPgFPIVLHGGSGIPDDQIQEAIKLGVAKVNVNTEC 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446197680 236 KIAFADALKGYF---------YNNPAANDPRHYMQPAKAAMKEVVTRIIGVCGSEGK 283
Cdd:PRK07315 236 QIAFANATRKFArdyeaneaeYDKKKLFDPRKFLAPGVKAIQASVEERIDVFGSANK 292
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 8-272 2.72e-30

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 116.31  E-value: 2.72e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   8 NMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVMLA-GTPGTYRYGGVG--------------SLISLVQSLARE 72
Cdd:cd00946    6 KLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQfSNGGAAFYAGKGlknekqkasiagaiAAAHHVRSMAEH 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  73 YNLPLVLHLDHHE-----------ESDDIFNKV--RAGIRSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLG 139
Cdd:cd00946   86 YGVPVVLHTDHCAkkllpwfdgllEADEEYFKQhgEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEMEIGITG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 140 GQEDDllVDEKDSA----YTSP----AAAAEFVQRTQIDSLAVAIGTAHGLYAH-----EPRL-----DFVRlEQIRQRV 201
Cdd:cd00946  166 GEEDG--VDNSGVDnaelYTQPedvwYVYEALSKISPNFSIAAAFGNVHGVYKPgnvklQPEIlgehqDYVR-EKLGLAD 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 202 EIPL--VLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADALKGYFYNNPA------------------ANDPRHYMQ 261
Cdd:cd00946  243 DKPLyfVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDylqgqignpegpdkpnkkYYDPRVWLR 322

                        330
                 ....*....|.
gi 446197680 262 PAKAAMKEVVT 272
Cdd:cd00946  323 EGEKSMVARVK 333
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 9-269 2.16e-25

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 102.95  E-value: 2.16e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680   9 MLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSPVM----------LAGT---PGTYRYGGVGSlISL---VQSLARE 72
Cdd:PRK09197  12 MFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIiqfsnggaafIAGKgvkDDGQGAAVLGA-IAGakhVHEVAEH 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680  73 YNLPLVLHLDHH------------EESDDIFNKVRAGI-RSVMIDGSHLPFEDNIARVQEVTTFCHRFDVSVEAELGRLG 139
Cdd:PRK09197  91 YGVPVILHTDHCakkllpwidgllDAGEKHFAAGGKPLfSSHMIDLSEEPLEENIEICSKYLERMAKAGMTLEIELGVTG 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 140 GQEDDLLVDEKDSA--YTSPAAAAEFVQRTQIDS----LAVAIGTAHGLYahEP---RLDFVRLEQIRQRVE-------- 202
Cdd:PRK09197 171 GEEDGVDNSHEDNSklYTQPEDVLYAYEALGKISgrftIAASFGNVHGVY--KPgnvKLRPEILKDSQEYVSkkfglpak 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446197680 203 -IPLVLHGASGLSEQDVQHCIRRGICKVNVATELKIAFADALKGYFYNNPA------------------ANDPRHYMQPA 263
Cdd:PRK09197 249 pFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDylqgqvgnpegedkpnkkYYDPRVWLRAA 328


                 ....*.
gi 446197680 264 KAAMKE 269
Cdd:PRK09197 329 EASMAA 334
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH