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Concise Results
Standard Results
Full Results
MULTISPECIES: class I adenylate cyclase [Enterobacteriaceae]
Protein Classification
class I adenylate cyclase ( domain architecture ID 11459653 )
class I adenylate cyclase catalyzes the conversion of ATP to cyclic AMP and pyrophosphate
List of domain hits
Name
Accession
Description
Interval
E-value
CyaA
COG3072 Adenylate cyclase, class I [Signal transduction mechanisms];
1-825
0e+00
Adenylate cyclase, class I [Signal transduction mechanisms];
Pssm-ID: 442306
Cd Length: 930
Bit Score: 1491.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 1 M YLYIE TL K QR LD A I NQLR VD RAL A AM GPAF QQV YS LLP T L L HY H HPL M PGY LD G N VP K GI CLY TPD ET Q RHY L NE L el Y 80
Cdd:COG3072 7 M RKDLK TL R QR FL A L NQLR LE RAL S AM SSRQ QQV LD LLP L L F HY N HPL L PGY VS G D VP A GI ANF TPD KR Q LQA L QR L -- A 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 81 R GMSVQDPPKG E L PI T G V Y T MGST S S VG QS C SSDLDIWVCH QSW LD S E E R Q LLQ R KC S L L E S WAASLGVEV S FFL I DENR 160
Cdd:COG3072 85 R SFDYKQRAQH E P PI L G L Y L MGST G S IA QS E SSDLDIWVCH DPD LD A E A R A LLQ Q KC E L I E Q WAASLGVEV H FFL M DENR 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 161 FRH N E SG SL G GE D CGS T QH I LLLDEFYRTA VR LAGKR I LW NM VP CD EE EH YD D YV M TL Y A Q G VLT P N EWLD L GGL SSLS A 240
Cdd:COG3072 165 FRH G E RE SL S GE N CGS A QH L LLLDEFYRTA IL LAGKR P LW WL VP PE EE HN YD E YV Q TL L A K G FIN P D EWLD F GGL GTIP A 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 241 EEYFGA S LWQLYK S IDSPYK A VLK T LLLEAYS W EYPN PR LL AKDI KQ RLHD GE IVSFG LDPY C MML E RVT E YL TAIE D FT 320
Cdd:COG3072 245 EEYFGA G LWQLYK G IDSPYK S VLK L LLLEAYS S EYPN TQ LL SLEF KQ AVYA GE LDLDE LDPY V MML R RVT R YL LERN D LK 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 321 RL D LVRRCFYLKV C EKLSR E -- RACVG WRRE V L TQ LV K EW E W DDA RLA M LDNRA N WKI D QVRE AH NEL L D AM MQSYRNLI 398
Cdd:COG3072 325 RL E LVRRCFYLKV N EKLSR P pr ERSKS WRRE L L ER LV R EW G W SEE RLA L LDNRA Q WKI E QVRE ER NEL V D EL MQSYRNLI 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 399 R FARRNN L S V S A SPQDIG V L T RKLYAAFE A LPGKVTL V NP Q ISPDLSE P NLTFI Y VP P GRANR S GWYLYN RAPNIES II S 478
Cdd:COG3072 405 Q FARRNN I S S S I SPQDIG I L G RKLYAAFE R LPGKVTL I NP G ISPDLSE E NLTFI Q VP E GRANR A GWYLYN QSLTPAD II G 484
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 479 H QPL E Y N R Y L NK LVAW AW FNGLLT SR TRL YI - K G NGIV D LPK LQ EM VAD VSH HFP LR LPAP TPK AL YS PCEIRHLA IIV N 557
Cdd:COG3072 485 R QPL K Y S R S L VE LVAW CY FNGLLT AS TRL HL h P G GSDL D EYE LQ QL VAD LRQ HFP VP LPAP SNE AL SR PCEIRHLA LFI N 564
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 558 L EY DPTA AFRNQVV HFD FRKL D VF SFG ENQNC LVGS V DL L YRNSWNEVRTLHF N G EQSMIE ALKT I LGKMHQDAAPP D S V 637
Cdd:COG3072 565 L GV DPTA HLSRRGI HFD SSRS D AL SFG GAREN LVGS I DL V YRNSWNEVRTLHF E G DDALLD ALKT L LGKMHQDAAPP P S I 644
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 638 E VFCYSQ HL RG L I RT RV Q QL VS ECI E LRL SS TRQ e TG R FKA LRV S GQ TW GLFFER LN VSVQKLENA IEF Y G A I S H NKL HG 717
Cdd:COG3072 645 D VFCYSQ TR RG A I AN RV E QL FN ECI S LRL GG TRQ - PN R RYL LRV A GQ YY GLFFER RG VSVQKLENA VDL Y R A L S E NKL SY 723
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 718 LSVQVE --- TNHVK LP A V V D G FASEG I IQFFFE ETQ D en GFNIYILDE S N RV E V Y HH CEG S KEEL V R DVS RFY S SS H DR F 794
Cdd:COG3072 724 SPLVLD rha LEDHP LP P V I D S FASEG L IQFFFE DNG D -- GFNIYILDE N N SL E I Y RQ CEG D KEEL L R PLN RFY R SS Q DR R 801
810 820 830
....*....|....*....|....*....|..
gi 446203841 795 TYGSSFINFNLPQFYQIV KV DG R E - QV I PFR T 825
Cdd:COG3072 802 TYGSSFINFNLPQFYQIV RN DG G E l QV E PFR S 833
Name
Accession
Description
Interval
E-value
CyaA
COG3072 Adenylate cyclase, class I [Signal transduction mechanisms];
1-825
0e+00
Adenylate cyclase, class I [Signal transduction mechanisms];
Pssm-ID: 442306
Cd Length: 930
Bit Score: 1491.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 1 M YLYIE TL K QR LD A I NQLR VD RAL A AM GPAF QQV YS LLP T L L HY H HPL M PGY LD G N VP K GI CLY TPD ET Q RHY L NE L el Y 80
Cdd:COG3072 7 M RKDLK TL R QR FL A L NQLR LE RAL S AM SSRQ QQV LD LLP L L F HY N HPL L PGY VS G D VP A GI ANF TPD KR Q LQA L QR L -- A 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 81 R GMSVQDPPKG E L PI T G V Y T MGST S S VG QS C SSDLDIWVCH QSW LD S E E R Q LLQ R KC S L L E S WAASLGVEV S FFL I DENR 160
Cdd:COG3072 85 R SFDYKQRAQH E P PI L G L Y L MGST G S IA QS E SSDLDIWVCH DPD LD A E A R A LLQ Q KC E L I E Q WAASLGVEV H FFL M DENR 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 161 FRH N E SG SL G GE D CGS T QH I LLLDEFYRTA VR LAGKR I LW NM VP CD EE EH YD D YV M TL Y A Q G VLT P N EWLD L GGL SSLS A 240
Cdd:COG3072 165 FRH G E RE SL S GE N CGS A QH L LLLDEFYRTA IL LAGKR P LW WL VP PE EE HN YD E YV Q TL L A K G FIN P D EWLD F GGL GTIP A 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 241 EEYFGA S LWQLYK S IDSPYK A VLK T LLLEAYS W EYPN PR LL AKDI KQ RLHD GE IVSFG LDPY C MML E RVT E YL TAIE D FT 320
Cdd:COG3072 245 EEYFGA G LWQLYK G IDSPYK S VLK L LLLEAYS S EYPN TQ LL SLEF KQ AVYA GE LDLDE LDPY V MML R RVT R YL LERN D LK 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 321 RL D LVRRCFYLKV C EKLSR E -- RACVG WRRE V L TQ LV K EW E W DDA RLA M LDNRA N WKI D QVRE AH NEL L D AM MQSYRNLI 398
Cdd:COG3072 325 RL E LVRRCFYLKV N EKLSR P pr ERSKS WRRE L L ER LV R EW G W SEE RLA L LDNRA Q WKI E QVRE ER NEL V D EL MQSYRNLI 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 399 R FARRNN L S V S A SPQDIG V L T RKLYAAFE A LPGKVTL V NP Q ISPDLSE P NLTFI Y VP P GRANR S GWYLYN RAPNIES II S 478
Cdd:COG3072 405 Q FARRNN I S S S I SPQDIG I L G RKLYAAFE R LPGKVTL I NP G ISPDLSE E NLTFI Q VP E GRANR A GWYLYN QSLTPAD II G 484
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 479 H QPL E Y N R Y L NK LVAW AW FNGLLT SR TRL YI - K G NGIV D LPK LQ EM VAD VSH HFP LR LPAP TPK AL YS PCEIRHLA IIV N 557
Cdd:COG3072 485 R QPL K Y S R S L VE LVAW CY FNGLLT AS TRL HL h P G GSDL D EYE LQ QL VAD LRQ HFP VP LPAP SNE AL SR PCEIRHLA LFI N 564
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 558 L EY DPTA AFRNQVV HFD FRKL D VF SFG ENQNC LVGS V DL L YRNSWNEVRTLHF N G EQSMIE ALKT I LGKMHQDAAPP D S V 637
Cdd:COG3072 565 L GV DPTA HLSRRGI HFD SSRS D AL SFG GAREN LVGS I DL V YRNSWNEVRTLHF E G DDALLD ALKT L LGKMHQDAAPP P S I 644
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 638 E VFCYSQ HL RG L I RT RV Q QL VS ECI E LRL SS TRQ e TG R FKA LRV S GQ TW GLFFER LN VSVQKLENA IEF Y G A I S H NKL HG 717
Cdd:COG3072 645 D VFCYSQ TR RG A I AN RV E QL FN ECI S LRL GG TRQ - PN R RYL LRV A GQ YY GLFFER RG VSVQKLENA VDL Y R A L S E NKL SY 723
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 718 LSVQVE --- TNHVK LP A V V D G FASEG I IQFFFE ETQ D en GFNIYILDE S N RV E V Y HH CEG S KEEL V R DVS RFY S SS H DR F 794
Cdd:COG3072 724 SPLVLD rha LEDHP LP P V I D S FASEG L IQFFFE DNG D -- GFNIYILDE N N SL E I Y RQ CEG D KEEL L R PLN RFY R SS Q DR R 801
810 820 830
....*....|....*....|....*....|..
gi 446203841 795 TYGSSFINFNLPQFYQIV KV DG R E - QV I PFR T 825
Cdd:COG3072 802 TYGSSFINFNLPQFYQIV RN DG G E l QV E PFR S 833
cyaA
PRK09450 class I adenylate cyclase;
1-824
0e+00
class I adenylate cyclase;
Pssm-ID: 236522 [Multi-domain]
Cd Length: 830
Bit Score: 1479.77
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 1 M YL Y I ETLKQRLDA I NQLR VD RALAA MG PAFQQV Y SLLP T LLH YH HPL M PGY LD GN V P K GIC LY TPDETQ RH YL NE LEL Y 80
Cdd:PRK09450 1 M RK Y L ETLKQRLDA L NQLR LA RALAA LS PAFQQV L SLLP L LLH VN HPL L PGY VS GN T P A GIC NF TPDETQ LA YL QR LEL S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 81 R G M SVQDPPKGELPITG V YTMGST S S V GQS C SSDLDIWVCH QS WLD S EERQLLQRKCSLLE S WAASLGVEV S FFL I DE N R 160
Cdd:PRK09450 81 F G Y SVQDPPKGELPITG L YTMGST G S I GQS E SSDLDIWVCH RP WLD A EERQLLQRKCSLLE Q WAASLGVEV N FFL M DE E R 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 161 FRHNESGS - LGGEDCGSTQHILLLDEFYRTA V RLAGKR I LW NM VP CD EEEHYDDYVMTLY AQ G V L T PNEWLDLGGLSSL S 239
Cdd:PRK09450 161 FRHNESGS a LGGEDCGSTQHILLLDEFYRTA I RLAGKR P LW WL VP VE EEEHYDDYVMTLY SK G F L N PNEWLDLGGLSSL P 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 240 AEEYFGASLWQLYK S IDSPYK A VLK T LLLEAYS W EYPN PR LL AK D I KQRL HD GEI V S F GLDPYC M MLERVT E YLTAI E D F 319
Cdd:PRK09450 241 AEEYFGASLWQLYK G IDSPYK S VLK L LLLEAYS S EYPN TQ LL SL D F KQRL LA GEI D S D GLDPYC L MLERVT R YLTAI N D P 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 320 TRL D LVRRCFYLKV C EKLSRERACVGWRRE V L T QLV K EW E WD DA RLA M LDNRANWKI D QVRE A HNEL L DA M MQSYRNLIR 399
Cdd:PRK09450 321 TRL E LVRRCFYLKV G EKLSRERACVGWRRE L L S QLV S EW G WD EE RLA L LDNRANWKI G QVRE F HNEL V DA L MQSYRNLIR 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 400 FARRNNLS V S A SPQDIG V LTRKLYAAFE A LPGKVTL V NPQISPDLSEP N LTFI Y VPPGRANRSGWYLYN R AP NIE SII S H 479
Cdd:PRK09450 401 FARRNNLS S S I SPQDIG I LTRKLYAAFE R LPGKVTL L NPQISPDLSEP D LTFI E VPPGRANRSGWYLYN Q AP DPD SII G H 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 480 QPLEYNRYLNKLVAWA W FNGLLTS R TRL YI KGN - GIV DL P KLQE M VAD VSH HFPLRLPAPTP K AL YS PCEIRHL A IIVNL 558
Cdd:PRK09450 481 QPLEYNRYLNKLVAWA Y FNGLLTS S TRL HL KGN g SDL DL A KLQE L VAD LRQ HFPLRLPAPTP Q AL LQ PCEIRHL L IIVNL 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 559 E Y DPTA AF R N QVVHFDFR K LDVFSFG EN Q NC LVGSVDL L YRNSWNEVRTLHF N GEQ SMIE ALKTILGKMHQDAAPP D SVE 638
Cdd:PRK09450 561 E V DPTA HL R G QVVHFDFR N LDVFSFG GE Q EN LVGSVDL I YRNSWNEVRTLHF E GEQ ALLD ALKTILGKMHQDAAPP P SVE 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 639 VFCYSQHLRGLIRTRVQQLVSECIELRL S STRQE T G rf KALRV S GQTWGLFFERL N VSVQKLENA I EFYGA I S H NKLHGL 718
Cdd:PRK09450 641 VFCYSQHLRGLIRTRVQQLVSECIELRL G STRQE P G -- KALRV A GQTWGLFFERL G VSVQKLENA V EFYGA L S E NKLHGL 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 719 S VQ VE TN HV KLPAVVDGFASEGIIQFFFE et QD E N GFN I YILDESNR V E V YHHCEGSKEELVRDVSRFYSSSHDRFTYGS 798
Cdd:PRK09450 719 P VQ LD TN FL KLPAVVDGFASEGIIQFFFE -- DN E D GFN V YILDESNR L E H YHHCEGSKEELVRDVSRFYSSSHDRFTYGS 796
810 820
....*....|....*....|....*.
gi 446203841 799 SFINFNLPQFYQ I V K VDGR E QVIPFR 824
Cdd:PRK09450 797 SFINFNLPQFYQ L V R VDGR L QVIPFR 822
Adenylate_cycl
pfam01295 Adenylate cyclase, class-I;
228-826
0e+00
Adenylate cyclase, class-I;
Pssm-ID: 426186
Cd Length: 601
Bit Score: 977.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 228 E WLDLGGLS S L S AEEYFGASLWQLYK S IDSPYKAVLK T LLLEAYS W EYPN PR LL AKDI K Q RL HD G EIV S FG LDPY CM MLE 307
Cdd:pfam01295 1 D WLDLGGLS A L P AEEYFGASLWQLYK G IDSPYKAVLK I LLLEAYS S EYPN TE LL SSQF K R RL LA G DFT S YH LDPY LL MLE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 308 RVT E YLT A I E DF T RLDLVRRCFYLK VC E K LSR E -- RACVG WRR EV L TQ LV KE W E W D D ARLAM LDNR AN WK ID QV RE A H N E 385
Cdd:pfam01295 81 RVT D YLT K I N DF K RLDLVRRCFYLK AG E G LSR L qp NGAKD WRR DK L QE LV QQ W H W S D ELIQT LDNR RH WK VG QV KW A N N Q 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 386 LL DAM M Q SYRNLI R FAR RN N L S V S A SP Q DIG V LTRKLY A AFE A LPGKVTL V NP Q ISPDLSEP N LTFI Y VP P GR A N RS GWY 465
Cdd:pfam01295 161 LL ELL M L SYRNLI Q FAR KH N I S E S I SP E DIG I LTRKLY T AFE E LPGKVTL L NP L ISPDLSEP D LTFI E VP E GR S N KA GWY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 466 LYN RA P NIESI I SHQ PLEY NR YL N KLVAWA W FNGLLT SR TRL YIKGN G i VDL P -- KL QEM V A D VSHH FP L R L P A PT PKA L 543
Cdd:pfam01295 241 LYN QP P DPADL I GRR PLEY AK YL S KLVAWA Y FNGLLT ES TRL HLVSQ G - VDL T sd KL SQF V T D LRLS FP V R A P K PT NQD L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 544 YS PCEIRHL A I IV NLE Y DPT AAFRN Q V V HF D FRKL D V FSFG EN Q NC LVGSVDL L YRNSWNE V RTLHF N GE QSMIE ALKTI 623
Cdd:pfam01295 320 SH PCEIRHL V I FI NLE Q DPT THWSG Q E V MV D IQNA D L FSFG RS Q EN LVGSVDL I YRNSWNE I RTLHF E GE NALLK ALKTI 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 624 L G K M H Q DAAPP D S VE VFCYS QH LR GLI R TR V Q QL VSE CIELRL SSTRQE T g RF K A LR VS G QTW GLFFER LN VSVQ K LENA 703
Cdd:pfam01295 400 L N K I H R DAAPP E S ID VFCYS RR LR SQL R NA V K QL LNR CIELRL GTIQSR T - QV K P LR IG G KNY GLFFER RG VSVQ D LENA 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 704 IE FYG A IS H NKL HG L SVQV -- ETNHVKL PA VV D G FASEG I IQFFFE E tq D E N GFN I YILDE S N RV E V YH H C E GSK E ELV R 781
Cdd:pfam01295 479 VD FYG Q IS R NKL VE L PRPE lg DDPFLHI PA II D A FASEG L IQFFFE D -- N E D GFN V YILDE K N EL E I YH Q C D GSK D ELV N 556
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 446203841 782 D V S RFY S SS HD R FTYGSS FINFNLPQFYQ I V K V D G REQ V I PFR TK 826
Cdd:pfam01295 557 E V N RFY A SS ES R KNTNPA FINFNLPQFYQ L V R V N G ELK V V PFR SS 601
Name
Accession
Description
Interval
E-value
CyaA
COG3072 Adenylate cyclase, class I [Signal transduction mechanisms];
1-825
0e+00
Adenylate cyclase, class I [Signal transduction mechanisms];
Pssm-ID: 442306
Cd Length: 930
Bit Score: 1491.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 1 M YLYIE TL K QR LD A I NQLR VD RAL A AM GPAF QQV YS LLP T L L HY H HPL M PGY LD G N VP K GI CLY TPD ET Q RHY L NE L el Y 80
Cdd:COG3072 7 M RKDLK TL R QR FL A L NQLR LE RAL S AM SSRQ QQV LD LLP L L F HY N HPL L PGY VS G D VP A GI ANF TPD KR Q LQA L QR L -- A 84
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 81 R GMSVQDPPKG E L PI T G V Y T MGST S S VG QS C SSDLDIWVCH QSW LD S E E R Q LLQ R KC S L L E S WAASLGVEV S FFL I DENR 160
Cdd:COG3072 85 R SFDYKQRAQH E P PI L G L Y L MGST G S IA QS E SSDLDIWVCH DPD LD A E A R A LLQ Q KC E L I E Q WAASLGVEV H FFL M DENR 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 161 FRH N E SG SL G GE D CGS T QH I LLLDEFYRTA VR LAGKR I LW NM VP CD EE EH YD D YV M TL Y A Q G VLT P N EWLD L GGL SSLS A 240
Cdd:COG3072 165 FRH G E RE SL S GE N CGS A QH L LLLDEFYRTA IL LAGKR P LW WL VP PE EE HN YD E YV Q TL L A K G FIN P D EWLD F GGL GTIP A 244
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 241 EEYFGA S LWQLYK S IDSPYK A VLK T LLLEAYS W EYPN PR LL AKDI KQ RLHD GE IVSFG LDPY C MML E RVT E YL TAIE D FT 320
Cdd:COG3072 245 EEYFGA G LWQLYK G IDSPYK S VLK L LLLEAYS S EYPN TQ LL SLEF KQ AVYA GE LDLDE LDPY V MML R RVT R YL LERN D LK 324
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 321 RL D LVRRCFYLKV C EKLSR E -- RACVG WRRE V L TQ LV K EW E W DDA RLA M LDNRA N WKI D QVRE AH NEL L D AM MQSYRNLI 398
Cdd:COG3072 325 RL E LVRRCFYLKV N EKLSR P pr ERSKS WRRE L L ER LV R EW G W SEE RLA L LDNRA Q WKI E QVRE ER NEL V D EL MQSYRNLI 404
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 399 R FARRNN L S V S A SPQDIG V L T RKLYAAFE A LPGKVTL V NP Q ISPDLSE P NLTFI Y VP P GRANR S GWYLYN RAPNIES II S 478
Cdd:COG3072 405 Q FARRNN I S S S I SPQDIG I L G RKLYAAFE R LPGKVTL I NP G ISPDLSE E NLTFI Q VP E GRANR A GWYLYN QSLTPAD II G 484
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 479 H QPL E Y N R Y L NK LVAW AW FNGLLT SR TRL YI - K G NGIV D LPK LQ EM VAD VSH HFP LR LPAP TPK AL YS PCEIRHLA IIV N 557
Cdd:COG3072 485 R QPL K Y S R S L VE LVAW CY FNGLLT AS TRL HL h P G GSDL D EYE LQ QL VAD LRQ HFP VP LPAP SNE AL SR PCEIRHLA LFI N 564
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 558 L EY DPTA AFRNQVV HFD FRKL D VF SFG ENQNC LVGS V DL L YRNSWNEVRTLHF N G EQSMIE ALKT I LGKMHQDAAPP D S V 637
Cdd:COG3072 565 L GV DPTA HLSRRGI HFD SSRS D AL SFG GAREN LVGS I DL V YRNSWNEVRTLHF E G DDALLD ALKT L LGKMHQDAAPP P S I 644
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 638 E VFCYSQ HL RG L I RT RV Q QL VS ECI E LRL SS TRQ e TG R FKA LRV S GQ TW GLFFER LN VSVQKLENA IEF Y G A I S H NKL HG 717
Cdd:COG3072 645 D VFCYSQ TR RG A I AN RV E QL FN ECI S LRL GG TRQ - PN R RYL LRV A GQ YY GLFFER RG VSVQKLENA VDL Y R A L S E NKL SY 723
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 718 LSVQVE --- TNHVK LP A V V D G FASEG I IQFFFE ETQ D en GFNIYILDE S N RV E V Y HH CEG S KEEL V R DVS RFY S SS H DR F 794
Cdd:COG3072 724 SPLVLD rha LEDHP LP P V I D S FASEG L IQFFFE DNG D -- GFNIYILDE N N SL E I Y RQ CEG D KEEL L R PLN RFY R SS Q DR R 801
810 820 830
....*....|....*....|....*....|..
gi 446203841 795 TYGSSFINFNLPQFYQIV KV DG R E - QV I PFR T 825
Cdd:COG3072 802 TYGSSFINFNLPQFYQIV RN DG G E l QV E PFR S 833
cyaA
PRK09450 class I adenylate cyclase;
1-824
0e+00
class I adenylate cyclase;
Pssm-ID: 236522 [Multi-domain]
Cd Length: 830
Bit Score: 1479.77
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 1 M YL Y I ETLKQRLDA I NQLR VD RALAA MG PAFQQV Y SLLP T LLH YH HPL M PGY LD GN V P K GIC LY TPDETQ RH YL NE LEL Y 80
Cdd:PRK09450 1 M RK Y L ETLKQRLDA L NQLR LA RALAA LS PAFQQV L SLLP L LLH VN HPL L PGY VS GN T P A GIC NF TPDETQ LA YL QR LEL S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 81 R G M SVQDPPKGELPITG V YTMGST S S V GQS C SSDLDIWVCH QS WLD S EERQLLQRKCSLLE S WAASLGVEV S FFL I DE N R 160
Cdd:PRK09450 81 F G Y SVQDPPKGELPITG L YTMGST G S I GQS E SSDLDIWVCH RP WLD A EERQLLQRKCSLLE Q WAASLGVEV N FFL M DE E R 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 161 FRHNESGS - LGGEDCGSTQHILLLDEFYRTA V RLAGKR I LW NM VP CD EEEHYDDYVMTLY AQ G V L T PNEWLDLGGLSSL S 239
Cdd:PRK09450 161 FRHNESGS a LGGEDCGSTQHILLLDEFYRTA I RLAGKR P LW WL VP VE EEEHYDDYVMTLY SK G F L N PNEWLDLGGLSSL P 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 240 AEEYFGASLWQLYK S IDSPYK A VLK T LLLEAYS W EYPN PR LL AK D I KQRL HD GEI V S F GLDPYC M MLERVT E YLTAI E D F 319
Cdd:PRK09450 241 AEEYFGASLWQLYK G IDSPYK S VLK L LLLEAYS S EYPN TQ LL SL D F KQRL LA GEI D S D GLDPYC L MLERVT R YLTAI N D P 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 320 TRL D LVRRCFYLKV C EKLSRERACVGWRRE V L T QLV K EW E WD DA RLA M LDNRANWKI D QVRE A HNEL L DA M MQSYRNLIR 399
Cdd:PRK09450 321 TRL E LVRRCFYLKV G EKLSRERACVGWRRE L L S QLV S EW G WD EE RLA L LDNRANWKI G QVRE F HNEL V DA L MQSYRNLIR 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 400 FARRNNLS V S A SPQDIG V LTRKLYAAFE A LPGKVTL V NPQISPDLSEP N LTFI Y VPPGRANRSGWYLYN R AP NIE SII S H 479
Cdd:PRK09450 401 FARRNNLS S S I SPQDIG I LTRKLYAAFE R LPGKVTL L NPQISPDLSEP D LTFI E VPPGRANRSGWYLYN Q AP DPD SII G H 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 480 QPLEYNRYLNKLVAWA W FNGLLTS R TRL YI KGN - GIV DL P KLQE M VAD VSH HFPLRLPAPTP K AL YS PCEIRHL A IIVNL 558
Cdd:PRK09450 481 QPLEYNRYLNKLVAWA Y FNGLLTS S TRL HL KGN g SDL DL A KLQE L VAD LRQ HFPLRLPAPTP Q AL LQ PCEIRHL L IIVNL 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 559 E Y DPTA AF R N QVVHFDFR K LDVFSFG EN Q NC LVGSVDL L YRNSWNEVRTLHF N GEQ SMIE ALKTILGKMHQDAAPP D SVE 638
Cdd:PRK09450 561 E V DPTA HL R G QVVHFDFR N LDVFSFG GE Q EN LVGSVDL I YRNSWNEVRTLHF E GEQ ALLD ALKTILGKMHQDAAPP P SVE 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 639 VFCYSQHLRGLIRTRVQQLVSECIELRL S STRQE T G rf KALRV S GQTWGLFFERL N VSVQKLENA I EFYGA I S H NKLHGL 718
Cdd:PRK09450 641 VFCYSQHLRGLIRTRVQQLVSECIELRL G STRQE P G -- KALRV A GQTWGLFFERL G VSVQKLENA V EFYGA L S E NKLHGL 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 719 S VQ VE TN HV KLPAVVDGFASEGIIQFFFE et QD E N GFN I YILDESNR V E V YHHCEGSKEELVRDVSRFYSSSHDRFTYGS 798
Cdd:PRK09450 719 P VQ LD TN FL KLPAVVDGFASEGIIQFFFE -- DN E D GFN V YILDESNR L E H YHHCEGSKEELVRDVSRFYSSSHDRFTYGS 796
810 820
....*....|....*....|....*.
gi 446203841 799 SFINFNLPQFYQ I V K VDGR E QVIPFR 824
Cdd:PRK09450 797 SFINFNLPQFYQ L V R VDGR L QVIPFR 822
Adenylate_cycl
pfam01295 Adenylate cyclase, class-I;
228-826
0e+00
Adenylate cyclase, class-I;
Pssm-ID: 426186
Cd Length: 601
Bit Score: 977.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 228 E WLDLGGLS S L S AEEYFGASLWQLYK S IDSPYKAVLK T LLLEAYS W EYPN PR LL AKDI K Q RL HD G EIV S FG LDPY CM MLE 307
Cdd:pfam01295 1 D WLDLGGLS A L P AEEYFGASLWQLYK G IDSPYKAVLK I LLLEAYS S EYPN TE LL SSQF K R RL LA G DFT S YH LDPY LL MLE 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 308 RVT E YLT A I E DF T RLDLVRRCFYLK VC E K LSR E -- RACVG WRR EV L TQ LV KE W E W D D ARLAM LDNR AN WK ID QV RE A H N E 385
Cdd:pfam01295 81 RVT D YLT K I N DF K RLDLVRRCFYLK AG E G LSR L qp NGAKD WRR DK L QE LV QQ W H W S D ELIQT LDNR RH WK VG QV KW A N N Q 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 386 LL DAM M Q SYRNLI R FAR RN N L S V S A SP Q DIG V LTRKLY A AFE A LPGKVTL V NP Q ISPDLSEP N LTFI Y VP P GR A N RS GWY 465
Cdd:pfam01295 161 LL ELL M L SYRNLI Q FAR KH N I S E S I SP E DIG I LTRKLY T AFE E LPGKVTL L NP L ISPDLSEP D LTFI E VP E GR S N KA GWY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 466 LYN RA P NIESI I SHQ PLEY NR YL N KLVAWA W FNGLLT SR TRL YIKGN G i VDL P -- KL QEM V A D VSHH FP L R L P A PT PKA L 543
Cdd:pfam01295 241 LYN QP P DPADL I GRR PLEY AK YL S KLVAWA Y FNGLLT ES TRL HLVSQ G - VDL T sd KL SQF V T D LRLS FP V R A P K PT NQD L 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 544 YS PCEIRHL A I IV NLE Y DPT AAFRN Q V V HF D FRKL D V FSFG EN Q NC LVGSVDL L YRNSWNE V RTLHF N GE QSMIE ALKTI 623
Cdd:pfam01295 320 SH PCEIRHL V I FI NLE Q DPT THWSG Q E V MV D IQNA D L FSFG RS Q EN LVGSVDL I YRNSWNE I RTLHF E GE NALLK ALKTI 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 624 L G K M H Q DAAPP D S VE VFCYS QH LR GLI R TR V Q QL VSE CIELRL SSTRQE T g RF K A LR VS G QTW GLFFER LN VSVQ K LENA 703
Cdd:pfam01295 400 L N K I H R DAAPP E S ID VFCYS RR LR SQL R NA V K QL LNR CIELRL GTIQSR T - QV K P LR IG G KNY GLFFER RG VSVQ D LENA 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 704 IE FYG A IS H NKL HG L SVQV -- ETNHVKL PA VV D G FASEG I IQFFFE E tq D E N GFN I YILDE S N RV E V YH H C E GSK E ELV R 781
Cdd:pfam01295 479 VD FYG Q IS R NKL VE L PRPE lg DDPFLHI PA II D A FASEG L IQFFFE D -- N E D GFN V YILDE K N EL E I YH Q C D GSK D ELV N 556
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 446203841 782 D V S RFY S SS HD R FTYGSS FINFNLPQFYQ I V K V D G REQ V I PFR TK 826
Cdd:pfam01295 557 E V N RFY A SS ES R KNTNPA FINFNLPQFYQ L V R V N G ELK V V PFR SS 601
Adenyl_cycl_N
pfam12633 Adenylate cyclase NT domain;
4-200
3.20e-112
Adenylate cyclase NT domain;
Pssm-ID: 432684 [Multi-domain]
Cd Length: 198
Bit Score: 340.70
E-value: 3.20e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 4 YI ETL K QR L DA I NQLR VD RALAA MG P AF QQV YS LLP T LLH YH HPL M PGY LD G NV P K GI CLYT P DET Q RHY L NE L ELYRGM 83
Cdd:pfam12633 1 DL ETL R QR F DA L NQLR LE RALAA LS P RQ QQV LR LLP L LLH VN HPL L PGY VS G DT P C GI ANFE P SKF Q LAL L DR L FRSFTY 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446203841 84 SVQDPPKGEL PI T G V Y T MGST S S VG QS C SSDLDIWVCH QSW LD S EE RQ LLQRKC S L L E S WAA SL GVEV S FFL I D EN RFR H 163
Cdd:pfam12633 81 KETKTDISDP PI L G L Y L MGST G S IA QS A SSDLDIWVCH RPG LD A EE LE LLQRKC Q L I E Q WAA QF GVEV H FFL M D PE RFR S 160
170 180 190
....*....|....*....|....*....|....*..
gi 446203841 164 N E S G SL GG E DC GS T QH I LLLDEFYRTA V RLAGKR I LW 200
Cdd:pfam12633 161 N R S S SL TE E SS GS A QH L LLLDEFYRTA I RLAGKR P LW 197
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
