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Conserved domains on  [gi|446204022|ref|WP_000281877|]
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MULTISPECIES: lipid A 3-O-deacylase PagL [Bacteria]

Protein Classification

acyloxyacyl hydrolase( domain architecture ID 10559446)

acyloxyacyl hydrolase has lipid A 3-O-deacylase activity; it hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PagL pfam09411
Lipid A 3-O-deacylase (PagL); PagL is an outer membrane protein with lipid A 3-O-deacylase ...
 97-186 8.21e-12

Lipid A 3-O-deacylase (PagL); PagL is an outer membrane protein with lipid A 3-O-deacylase activity. It forms an 8 stranded beta barrel structure.


:

Pssm-ID: 462791  Cd Length: 129  Bit Score: 59.80  E-value: 8.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204022   97 YNQGVLGISKDVALVHFAGIYTGIGLGAYIKSKSR-DDMRVNSAFTFGEKAFLGWNFG--AFSTEAYIRHFSNGSLTDKN 173
Cdd:pfam09411  37 LGLGVTPVFRFFFWSGKRGPYLEAGIGVAYLSRTNfGDNDLGTRFQFRDQAGLGYRFGegNLSLGLRFQHYSNAGIKDPN 116

                          90
                  ....*....|...
gi 446204022  174 SGHNFVGASISYN 186
Cdd:pfam09411 117 PGLNSLGLNLGYR 129
 
Name Accession Description Interval E-value
PagL pfam09411
Lipid A 3-O-deacylase (PagL); PagL is an outer membrane protein with lipid A 3-O-deacylase ...
 97-186 8.21e-12

Lipid A 3-O-deacylase (PagL); PagL is an outer membrane protein with lipid A 3-O-deacylase activity. It forms an 8 stranded beta barrel structure.


Pssm-ID: 462791  Cd Length: 129  Bit Score: 59.80  E-value: 8.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204022   97 YNQGVLGISKDVALVHFAGIYTGIGLGAYIKSKSR-DDMRVNSAFTFGEKAFLGWNFG--AFSTEAYIRHFSNGSLTDKN 173
Cdd:pfam09411  37 LGLGVTPVFRFFFWSGKRGPYLEAGIGVAYLSRTNfGDNDLGTRFQFRDQAGLGYRFGegNLSLGLRFQHYSNAGIKDPN 116

                          90
                  ....*....|...
gi 446204022  174 SGHNFVGASISYN 186
Cdd:pfam09411 117 PGLNSLGLNLGYR 129
 
Name Accession Description Interval E-value
PagL pfam09411
Lipid A 3-O-deacylase (PagL); PagL is an outer membrane protein with lipid A 3-O-deacylase ...
 97-186 8.21e-12

Lipid A 3-O-deacylase (PagL); PagL is an outer membrane protein with lipid A 3-O-deacylase activity. It forms an 8 stranded beta barrel structure.


Pssm-ID: 462791  Cd Length: 129  Bit Score: 59.80  E-value: 8.21e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204022   97 YNQGVLGISKDVALVHFAGIYTGIGLGAYIKSKSR-DDMRVNSAFTFGEKAFLGWNFG--AFSTEAYIRHFSNGSLTDKN 173
Cdd:pfam09411  37 LGLGVTPVFRFFFWSGKRGPYLEAGIGVAYLSRTNfGDNDLGTRFQFRDQAGLGYRFGegNLSLGLRFQHYSNAGIKDPN 116

                          90
                  ....*....|...
gi 446204022  174 SGHNFVGASISYN 186
Cdd:pfam09411 117 PGLNSLGLNLGYR 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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