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Conserved domains on  [gi|446211458|ref|WP_000289313|]
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MULTISPECIES: ABC transporter permease [Bacillus]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 2-302 8.25e-114

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 331.26  E-value: 8.25e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSSDA-KIFPEEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESVQs 80
Cdd:COG0601    4 YILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLgPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  81 TGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFELL 160
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 161 PVASW--------GTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTF 232
Cdd:COG0601  163 PVSGRvspwedflDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 233 VGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 2-302 8.25e-114

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 331.26  E-value: 8.25e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSSDA-KIFPEEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESVQs 80
Cdd:COG0601    4 YILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLgPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  81 TGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFELL 160
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 161 PVASW--------GTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTF 232
Cdd:COG0601  163 PVSGRvspwedflDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 233 VGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
oppB PRK09471
oligopeptide ABC transporter permease OppB;
2-302 6.62e-81

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 247.29  E-value: 6.62e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSSDaKIFPEEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESVQST 81
Cdd:PRK09471   4 FILRRCLEAIPTLFILITISFFMMRLAPGSPFTGE-RTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  82 GQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFELLP 161
Cdd:PRK09471  83 DYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHWLP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 162 VASW--GTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMAG 239
Cdd:PRK09471 163 GGGWngGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAFVG 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446211458 240 LLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:PRK09471 243 IITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 2-302 8.72e-64

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 203.45  E-value: 8.72e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458    2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDP---FSSDAKIFP-EEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGES 77
Cdd:TIGR02789   4 YILRRLLLLIPVVLAASLLAFILIHLGPSDPaedYLRLSHIPPtDEAIADMRHSLGLDQPLYVQYFHWLWNALHLDFGIS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   78 VqSTGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQF 157
Cdd:TIGR02789  84 Y-ISDRPVLDEIARSLPATLELAGFALVIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGVSIPNFWLAFLLVWGFSVYL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  158 ELLPVASWGTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLM 237
Cdd:TIGR02789 163 NLLPTNGAGTWQHLVLPAVTLALMSVSIYARLLRASMLDNMQERYVTYARVRGIKERWVIRRHILRNAILPMITALGMHI 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446211458  238 AGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:TIGR02789 243 GELLGGTFVIENIFSWPGVGRYAISAIFNRDYPVIQCYTLLMGLLFVFCNLIVDLFQALLDPRIR 307
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 111-302 6.07e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.22  E-value: 6.07e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  111 GIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLfiqvlaiqfeLLPVASWGTFEHTVLPSFALALGPIAVITRFV 190
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAIL----------LVVIAILSILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  191 RSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYP 270
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|..
gi 446211458  271 VIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-285 1.69e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.91  E-value: 1.69e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  93 FGPSAIIGLQALIISLLVGIAAGTFAALYHGKViDYGVSLLAILGISIPSFILAPLFIQVLAIQFEllpvasWGTFEHTV 172
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG------WGILPGLG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 173 LPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMAGLLTGTFVIEKIFS 252
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 446211458 253 ----IPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIV 285
Cdd:cd06261  154 geapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 2-302 8.25e-114

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 331.26  E-value: 8.25e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSSDA-KIFPEEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESVQs 80
Cdd:COG0601    4 YILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLgPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTSFV- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  81 TGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFELL 160
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 161 PVASW--------GTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTF 232
Cdd:COG0601  163 PVSGRvspwedflDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 233 VGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:COG0601  243 LGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
oppB PRK09471
oligopeptide ABC transporter permease OppB;
2-302 6.62e-81

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 247.29  E-value: 6.62e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSSDaKIFPEEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESVQST 81
Cdd:PRK09471   4 FILRRCLEAIPTLFILITISFFMMRLAPGSPFTGE-RTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  82 GQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFELLP 161
Cdd:PRK09471  83 DYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHWLP 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 162 VASW--GTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMAG 239
Cdd:PRK09471 163 GGGWngGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAFVG 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446211458 240 LLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:PRK09471 243 IITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
nickel_nikB TIGR02789
nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of ...
 2-302 8.72e-64

nickel ABC transporter, permease subunit NikB; This family consists of the NikB family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikC. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131836 [Multi-domain]  Cd Length: 314  Bit Score: 203.45  E-value: 8.72e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458    2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDP---FSSDAKIFP-EEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGES 77
Cdd:TIGR02789   4 YILRRLLLLIPVVLAASLLAFILIHLGPSDPaedYLRLSHIPPtDEAIADMRHSLGLDQPLYVQYFHWLWNALHLDFGIS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   78 VqSTGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQF 157
Cdd:TIGR02789  84 Y-ISDRPVLDEIARSLPATLELAGFALVIVVLVSVPLGILAARYRDRLPDHAVRFIIFLGVSIPNFWLAFLLVWGFSVYL 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  158 ELLPVASWGTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLM 237
Cdd:TIGR02789 163 NLLPTNGAGTWQHLVLPAVTLALMSVSIYARLLRASMLDNMQERYVTYARVRGIKERWVIRRHILRNAILPMITALGMHI 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446211458  238 AGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:TIGR02789 243 GELLGGTFVIENIFSWPGVGRYAISAIFNRDYPVIQCYTLLMGLLFVFCNLIVDLFQALLDPRIR 307
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 2-302 3.18e-59

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 191.47  E-value: 3.18e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSSDAKifPE---EVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESV 78
Cdd:PRK15081   4 YVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAG--PEadaQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSM 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  79 QSTgQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFE 158
Cdd:PRK15081  82 VSR-RPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 159 LLPVASWGTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMA 238
Cdd:PRK15081 161 WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFG 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446211458 239 GLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:PRK15081 241 FLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 2-302 1.44e-56

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 184.90  E-value: 1.44e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDP---FSSDAKIFP-EEVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGES 77
Cdd:PRK10352   4 YILRRLLLLIPMLLAASVIIFLMLRLGTGDPaldYLRLSNLPPtPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGIS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  78 VqSTGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQF 157
Cdd:PRK10352  84 F-ATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 158 ELLPVASWGTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLM 237
Cdd:PRK10352 163 QWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMHI 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446211458 238 AGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:PRK10352 243 GELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIR 307
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
2-302 9.48e-54

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 178.47  E-value: 9.48e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDP---FSSDAKIFPEEVIQNMrAKYHLDEPLWNQYVAYLDGVVHFDFGESV 78
Cdd:PRK10914   4 FILRRLGLVIPTFIGITLLTFAFVHMIPGDPvmiMAGERGISPERHAQLL-AELGLDKPMWQQYLHYIWGVMHGDLGISL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  79 QSTGQGVSEIITTgFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFE 158
Cdd:PRK10914  83 KSRIPVWDEFVPR-FKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWN 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 159 LLPVAS------------------------WG-------TFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLAR 207
Cdd:PRK10914 162 LTPVSGrvsdmvflddsnpltgfmlidtaiWGedgnfidAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTAR 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 208 AKGIPIKKIIIRHALRNAIVPVLTFVGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCI 287
Cdd:PRK10914 242 AKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVN 321

                        330
                 ....*....|....*
gi 446211458 288 FITDIIHRIVDPRIR 302
Cdd:PRK10914 322 LLVDLLYGVVNPRIR 336
YejB COG4174
ABC-type microcin C transport system, permease component YejB [Secondary metabolites ...
 2-301 3.75e-34

ABC-type microcin C transport system, permease component YejB [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443333 [Multi-domain]  Cd Length: 363  Bit Score: 127.61  E-value: 3.75e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDP------------------FSSD------------------AKIFPEEVI 45
Cdd:COG4174    4 YILRRLLLMIPTLLGIMLINFVIVQFAPGGPveqviaqlqgtgggatgrISGGggdagggaaagggskyrgARGLDPEFI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  46 QNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESVQStGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKV 125
Cdd:COG4174   84 AELEKQYGFDKPAHERFLLMLKNYLRFDFGESYFR-DISVIDLILEKLPVSISLGLWSTLLTYLISIPLGIRKAVRDGSR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 126 IDYGVSLLAILGISIPSFILAPLFIQVLA--IQFELLPV----------ASWGT-----FEHTVLPSFALALGPIAVITR 188
Cdd:COG4174  163 FDVWTSTVIIVGYAIPGFLFAILLIVLFAggSYFDWFPLrgltsdnwdqLSWWGkildyLWHLTLPVTAMVIGGFATLTL 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 189 FVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLT-FVGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNR 267
Cdd:COG4174  243 LTKNSFLDEIRKQYVLTARAKGLSERRVLYGHVFRNAMLIVIAgFPAAFIGAFFTGSLLIETIFSLDGLGLLGFEAVVNR 322

                        330       340       350
                 ....*....|....*....|....*....|....
gi 446211458 268 DYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRI 301
Cdd:COG4174  323 DYPVVFGTLYIFTLIGLVLKLISDLTYVLVDPRI 356
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 2-301 7.62e-32

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 121.39  E-value: 7.62e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   2 YVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSS---------------------------------------DAKIFPE 42
Cdd:PRK15133   4 YLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQaiaaiefgqagglpgaggegvrashaqtgvgnisdsnyrGGRGLDP 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  43 EVIQNMRAKYHLDEPLWNQYVAYLDGVVHFDFGESVqSTGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYH 122
Cdd:PRK15133  84 EVIAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSL-FRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRN 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 123 GKVIDYGVSLLAILGISIPSFILAPLFIQVLA---------------IQFELLPVASWGT--FEHTVLPSFALALGPIAV 185
Cdd:PRK15133 163 GSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAggsyfdlfplrglvsANFDSLPWYQKITdyLWHITLPVLATVIGGFAA 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 186 ITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLT-FVGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSI 264
Cdd:PRK15133 243 LTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAgFPATFISMFFTGSLLIEVMFSLNGLGLLGYEAT 322

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 446211458 265 FNRDYPVIMGTTIFYSALLIVCIFITDIIHRIVDPRI 301
Cdd:PRK15133 323 VSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
PRK15110 PRK15110
peptide ABC transporter permease SapB;
1-299 1.19e-31

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 120.18  E-value: 1.19e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458   1 MYVIKKLSVMVFTLWVITTVTFLIMHIIPGDPFSSDAkifpeeviqnmrakyhldepLWNQYVAYLDGVVHFDFGESvQS 80
Cdd:PRK15110   3 IFTLRRLLLLIVTLFLLTLVGFSLSYFTPHAPLQGAS--------------------LWDAWVFWFNGLLHWDFGVS-SI 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  81 TGQGVSEIITTGFGPSAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAIQFELL 160
Cdd:PRK15110  62 NGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 161 PVA-------------------SW------------GTFEHTVLPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAK 209
Cdd:PRK15110 142 PVSgrfdllyevkpvtgfalidAWlsdspwrdemimSAIRHMILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATR 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 210 GIPIKKIIIRHALRNAIVPVLTFVGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIVCIFI 289
Cdd:PRK15110 222 GLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVL 301

                        330
                 ....*....|
gi 446211458 290 TDIIHRIVDP 299
Cdd:PRK15110 302 SDILGAMANP 311
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 111-302 6.07e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.22  E-value: 6.07e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  111 GIAAGTFAALYHGKVIDYGVSLLAILGISIPSFILAPLfiqvlaiqfeLLPVASWGTFEHTVLPSFALALGPIAVITRFV 190
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAIL----------LVVIAILSILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  191 RSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMAGLLTGTFVIEKIFSIPGLGKYFVDSIFNRDYP 270
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|..
gi 446211458  271 VIMGTTIFYSALLIVCIFITDIIHRIVDPRIR 302
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVR 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-285 1.69e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 61.91  E-value: 1.69e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  93 FGPSAIIGLQALIISLLVGIAAGTFAALYHGKViDYGVSLLAILGISIPSFILAPLFIQVLAIQFEllpvasWGTFEHTV 172
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKL-DRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG------WGILPGLG 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 173 LPSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMAGLLTGTFVIEKIFS 252
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 446211458 253 ----IPGLGKYFVDSIFNRDYPVIMGTTIFYSALLIV 285
Cdd:cd06261  154 geapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 96-299 5.72e-08

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 53.45  E-value: 5.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  96 SAIIGLQALIISLLVGIAAGTFAALYHGKVIDYGVSLLAILGiSIPSFILAPLFIQVLAIQFellpvasWGTFEHTVLPS 175
Cdd:PRK15021 143 SVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWS-GMPTLFLIILLSSVVQPNF-------WWLLAITVLFG 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458 176 FaLALGPIavitrfVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVLTFVGPLMAGLLTGTFVIEKI----- 250
Cdd:PRK15021 215 W-MSLVGV------VRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLgfglp 287

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446211458 251 FSIPGLGKYFVDSIFNRDYPvIMGTTIFYSA--LLIVCIFITDIIHRIVDP 299
Cdd:PRK15021 288 LGSPSLGELLLQGKNNLQAP-WLGITAFLSVaiLLSLLIFIGEAVRDAFDP 337
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 92-230 1.99e-07

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 51.27  E-value: 1.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  92 GFGPSAIIGLQALIISLLVGIAAGTFAAlYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLAiqfellpvASWGTFeht 171
Cdd:COG1173   77 GARISLLVGLLAVLIALVIGVLLGLLAG-YFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG--------PGLLNV--- 144

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446211458 172 vlpSFALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVL 230
Cdd:COG1173  145 ---ILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLI 200
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 10-71 3.50e-05

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 42.21  E-value: 3.50e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446211458   10 MVFTLWVITTVTFLIMHIIPGDP-FSSDAKIFPEEVIQNMRAKYHLDEPLWNQYVAYLDGVVH 71
Cdd:pfam19300  12 AVVILLIISAVTFFLFYAIPRDPaRLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGIFA 74
nikC PRK10417
nickel transporter permease NikC; Provisional
 96-230 5.49e-03

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 37.73  E-value: 5.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446211458  96 SAIIGLqALIISLLVGIAAGtfaalYHGKVIDYGVSLLAILGISIPSFILAPLFIQVLaiqfellpvaswGTFEHTVLps 175
Cdd:PRK10417  74 MACLLL-VLALGLVIGGSAG-----LLGGRVDQATMRVADMFMTFPTSILAFFMVGVL------------GTGLTNVI-- 133

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446211458 176 FALALGPIAVITRFVRSNMIEVLQSDYIKLARAKGIPIKKIIIRHALRNAIVPVL 230
Cdd:PRK10417 134 IAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLL 188
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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