|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
115-507 |
2.63e-100 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 306.70 E-value: 2.63e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 115 LGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKeahdlqeaNTNQT 194
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAA--------ALGSE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 195 SIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLRYVaFRHDLK 274
Cdd:COG0471 73 KRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRL-LPPEIK 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 275 YLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLlkkwevtsSVADGTIAIFISILLFIIpakntekhrRI 354
Cdd:COG0471 152 EVPGSKEVIREELAELGPLSRREKIALAIFALTVLLWITGSLH--------GIPIAVVALLGAVLLLLT---------GV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 355 IDW-EVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKS-LNGVSPILIVIVITIFVLFLTEVTSNTATATMILPI 432
Cdd:COG0471 215 LTWkDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPI 294
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446245312 433 LATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPI 507
Cdd:COG0471 295 AISLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLWWPL 369
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
63-505 |
7.01e-74 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 239.02 E-value: 7.01e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 63 LAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIG 142
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 143 ASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQeantnqtsiqkfeKSLVLAIGYAGTIGGLGTLIGT 222
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP-------------SRLLMPLAFAASIGGMLTLIGT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 223 PPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLRYVAFrhdlkylpggqtlikqkldelgkmkyeekvVQT 302
Cdd:cd01115 148 PPNLVASGYLESLGGQGFSFFEFTPIGLPLLIIGLLYLWFIFRLAVL------------------------------IIT 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 303 IFVLASLLWITREFLLkkwevtsSVADGTIAIFISILlfiipakntekhRRIIDWEVAKELPWGVLILFGGGLALAKGIS 382
Cdd:cd01115 198 IVLLAALAAITGLLPV-------SVAIAIGAIVLVFG------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALE 258
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 383 ESGLAKWLGEQLKS-LNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYML 461
Cdd:cd01115 259 SSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFML 338
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 446245312 462 PVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVM 505
Cdd:cd01115 339 PVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
63-500 |
8.07e-68 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 224.92 E-value: 8.07e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 63 LAITLWIATWWITEAIPIAATSLLPI----VLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTII 138
Cdd:TIGR00785 14 LAIFVAAIVGWILEPLPLPVTALLAIpiiaVLLGVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 139 NLIGASTSKI-LLGFMVATGFLSMFVSNTA-AVMIMIPIGLAIIKeAHDLQEANtnqtSIQKFEKSLVLAIGYAGTIGGL 216
Cdd:TIGR00785 94 GKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLP-LLGSKPEK----SPRKIGKYLMLGIAYSASIGSS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 217 GTLIGTPPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLrYVAFRHDLKYLPGGQTLIKQKLDELGKMKYE 296
Cdd:TIGR00785 169 GFLTGSAPNALAAGILSKILGIQISWGDWFLAGLPLGIILLLLVPLLL-YVLFPPELKLKDEVDLWAKEELEEMGPMSFR 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 297 EKVVQTIFVLASLLWITREFLLKKwevtssvaDGTIAIFISILLFIIpakntekhrRIIDWEVAKELP--WGVLILFGGG 374
Cdd:TIGR00785 248 EKALLGIFLLALLLWIFGGSLGIN--------ASVVALLAVVLMLFL---------GIVTWKDIQKNKvaWNTLILFGGL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 375 LALAKGISESGLAKWLGEQLK-SLNGVSP-ILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAA 452
Cdd:TIGR00785 311 IGLAGGLKKSGFIKWFSEKLVgILDGLSPtIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALA 390
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 446245312 453 MAANCA-YMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILV 500
Cdd:TIGR00785 391 LSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLV 439
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
51-500 |
3.60e-63 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 213.39 E-value: 3.60e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 51 HPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTP----EQVSSEYGNDIIFLFLGGFILAIAMER 126
Cdd:pfam00939 22 APDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLakalSWALSGFSSTTTWLVFGAFFISAAFEK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 127 WNLHTRVALTIINLIGASTskILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLA 206
Cdd:pfam00939 102 TGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAFGSDPEKGSERRIGAYLMWT 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 207 IGYAGTIGGLGTLIGTPPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLrYVAFRHDLKYLPGGQTLIKQK 286
Cdd:pfam00939 180 VYQSTSITSAMFLTAMAPNLLLLGLMNSILGVTITWASWFLAAIPPGVILLLLAPLLL-YVLYPPEIKSVPDAKAIAKTE 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 287 LDELGKMKYEEKVVQTIFVLASLLWITREFLlkkwevtsSVADGTIAIFISILLFIIpakntekhrRIIDWE--VAKELP 364
Cdd:pfam00939 259 LKELGPMTFREKALLGLFVLLLLLWIFGGSL--------NIDATTVAIIGLALMLLL---------RILDWKdiVKNKGA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 365 WGVLILFGGGLALAKGISESGLAKWLGEQLK-SLNGVSPILIVIVI-TIFVLFLTEVTSNTATATMILPILATLSVAVGV 442
Cdd:pfam00939 322 WNTLIWLGGLIMLANGLERSGFIEWLGNTLStSLSGFSPAMAFIIIlSLFYLSHYLFASATAHTAAMLPIFAAVAQAIPG 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 443 HPLLLMAPAAMAANC--AYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILV 500
Cdd:pfam00939 402 APPLLAALLLGFAISlgGFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLL 461
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
115-507 |
2.63e-100 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 306.70 E-value: 2.63e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 115 LGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKeahdlqeaNTNQT 194
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAA--------ALGSE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 195 SIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLRYVaFRHDLK 274
Cdd:COG0471 73 KRSKFGSALLLPIAFAASIGGMGTLIGTPPNLIAAGLLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRL-LPPEIK 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 275 YLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLlkkwevtsSVADGTIAIFISILLFIIpakntekhrRI 354
Cdd:COG0471 152 EVPGSKEVIREELAELGPLSRREKIALAIFALTVLLWITGSLH--------GIPIAVVALLGAVLLLLT---------GV 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 355 IDW-EVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKS-LNGVSPILIVIVITIFVLFLTEVTSNTATATMILPI 432
Cdd:COG0471 215 LTWkDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALLPlLGGLSPLLLLLLLALLTLLLTEFASNTATAALLLPI 294
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446245312 433 LATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPI 507
Cdd:COG0471 295 AISLAQALGVNPLPLALAVAFAASCAFLLPVGTPPNAIVYGSGYYKFKDFLKVGLPLNLIGLVVLLLLGPLWWPL 369
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
63-505 |
7.01e-74 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 239.02 E-value: 7.01e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 63 LAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIG 142
Cdd:cd01115 1 LAILVFAAVLFVTEALPLDVTALLVPVLLVLLGVVPPKEAFSGFSDPAVILFLAGFILGAALTRTGLAKRIATKLLKRAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 143 ASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQeantnqtsiqkfeKSLVLAIGYAGTIGGLGTLIGT 222
Cdd:cd01115 81 KGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISP-------------SRLLMPLAFAASIGGMLTLIGT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 223 PPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLRYVAFrhdlkylpggqtlikqkldelgkmkyeekvVQT 302
Cdd:cd01115 148 PPNLVASGYLESLGGQGFSFFEFTPIGLPLLIIGLLYLWFIFRLAVL------------------------------IIT 197
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 303 IFVLASLLWITREFLLkkwevtsSVADGTIAIFISILlfiipakntekhRRIIDWEVAKELPWGVLILFGGGLALAKGIS 382
Cdd:cd01115 198 IVLLAALAAITGLLPV-------SVAIAIGAIVLVFG------------GVLLTKEDYKSIDWGIIFLFAGGIPLGKALE 258
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 383 ESGLAKWLGEQLKS-LNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYML 461
Cdd:cd01115 259 SSGAAALIAEALISlLGGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASCAFML 338
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 446245312 462 PVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVM 505
Cdd:cd01115 339 PVGTPPNAIVLGPGGYKFSDFAKVGLPLSILSLVVSVTMIPLIW 382
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
63-500 |
8.07e-68 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 224.92 E-value: 8.07e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 63 LAITLWIATWWITEAIPIAATSLLPI----VLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTII 138
Cdd:TIGR00785 14 LAIFVAAIVGWILEPLPLPVTALLAIpiiaVLLGVLSAFKFKNALSGFADPTIWLFFGAFILATALVKTGLGKRIAYKLV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 139 NLIGASTSKI-LLGFMVATGFLSMFVSNTA-AVMIMIPIGLAIIKeAHDLQEANtnqtSIQKFEKSLVLAIGYAGTIGGL 216
Cdd:TIGR00785 94 GKMGGTTLGLgYFLVFLETLLAPMWPSNTArAGGILLPIIKSLLP-LLGSKPEK----SPRKIGKYLMLGIAYSASIGSS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 217 GTLIGTPPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLrYVAFRHDLKYLPGGQTLIKQKLDELGKMKYE 296
Cdd:TIGR00785 169 GFLTGSAPNALAAGILSKILGIQISWGDWFLAGLPLGIILLLLVPLLL-YVLFPPELKLKDEVDLWAKEELEEMGPMSFR 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 297 EKVVQTIFVLASLLWITREFLLKKwevtssvaDGTIAIFISILLFIIpakntekhrRIIDWEVAKELP--WGVLILFGGG 374
Cdd:TIGR00785 248 EKALLGIFLLALLLWIFGGSLGIN--------ASVVALLAVVLMLFL---------GIVTWKDIQKNKvaWNTLILFGGL 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 375 LALAKGISESGLAKWLGEQLK-SLNGVSP-ILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAA 452
Cdd:TIGR00785 311 IGLAGGLKKSGFIKWFSEKLVgILDGLSPtIAVLVLVVLFYIILYFFASNTAHTAALVPIFFSVASAQGIPLELLALALA 390
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 446245312 453 MAANCA-YMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILV 500
Cdd:TIGR00785 391 LSASLMgFLTPYATPPNAIAYGSGYVKIKDMWRVGAIIGIVGLIVLLLV 439
|
|
| Na_sulph_symp |
pfam00939 |
Sodium:sulfate symporter transmembrane region; There are also some members in this family that ... |
51-500 |
3.60e-63 |
|
Sodium:sulfate symporter transmembrane region; There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.
Pssm-ID: 279307 [Multi-domain] Cd Length: 472 Bit Score: 213.39 E-value: 3.60e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 51 HPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTP----EQVSSEYGNDIIFLFLGGFILAIAMER 126
Cdd:pfam00939 22 APDGLPSKAWHLFAIFIATIVGWILEPLPMAVIALFAISLSAILIGTLLakalSWALSGFSSTTTWLVFGAFFISAAFEK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 127 WNLHTRVALTIINLIGASTskILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLA 206
Cdd:pfam00939 102 TGLGRRIALVLVKKMGKRT--LGLGYGLVFSDLLLAPATPSNTARAGGIVFPIIMSLPPAFGSDPEKGSERRIGAYLMWT 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 207 IGYAGTIGGLGTLIGTPPLIILKGQYMQHFGYEISFAKWMIVGIPTVIVLLGITWLYLrYVAFRHDLKYLPGGQTLIKQK 286
Cdd:pfam00939 180 VYQSTSITSAMFLTAMAPNLLLLGLMNSILGVTITWASWFLAAIPPGVILLLLAPLLL-YVLYPPEIKSVPDAKAIAKTE 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 287 LDELGKMKYEEKVVQTIFVLASLLWITREFLlkkwevtsSVADGTIAIFISILLFIIpakntekhrRIIDWE--VAKELP 364
Cdd:pfam00939 259 LKELGPMTFREKALLGLFVLLLLLWIFGGSL--------NIDATTVAIIGLALMLLL---------RILDWKdiVKNKGA 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 365 WGVLILFGGGLALAKGISESGLAKWLGEQLK-SLNGVSPILIVIVI-TIFVLFLTEVTSNTATATMILPILATLSVAVGV 442
Cdd:pfam00939 322 WNTLIWLGGLIMLANGLERSGFIEWLGNTLStSLSGFSPAMAFIIIlSLFYLSHYLFASATAHTAAMLPIFAAVAQAIPG 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 443 HPLLLMAPAAMAANC--AYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILV 500
Cdd:pfam00939 402 APPLLAALLLGFAISlgGFLTPYGTGPGPIYFGSGYLKVKDWWRIGAILTIIGLLILLLL 461
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
72-443 |
5.90e-50 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 174.81 E-value: 5.90e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 72 WWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLG 151
Cdd:pfam03600 3 LIITEKLPRDVVALLGAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 152 FMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLqeantnqtsiqkfEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQ 231
Cdd:pfam03600 83 LMLATALLSAFLSNDGTVLIMIPIVLALARRLGLP-------------PSPLLIALAFAANIGGTATPIGDPPNIIIASA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 232 YMQHFGyEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKylpggqtliKQKLDELGKMKYEEKVVQTIFVLASLLW 311
Cdd:pfam03600 150 LGLSFG-DFGFFMFPPVGVALLLVGLLPLLLIFRKLLPVRKEE---------EAELEELRKRAIKDKLLLAISALVLALV 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 312 ITREFLLKKWEVTSSVADGTIaifisillfiipakntekhRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLG 391
Cdd:pfam03600 220 ILGFLLLSVLALAGALLLLLT-------------------GVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALA 280
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 446245312 392 EQLKSLNGvsPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVH 443
Cdd:pfam03600 281 DALGGLSG--LLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLG 330
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
72-501 |
3.10e-45 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 163.57 E-value: 3.10e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 72 WWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINlIGASTSKILLG 151
Cdd:cd00625 3 LIRPEKLPRAVVALLGAVLLVLLGVVSPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLAR-ASKGSRRLLLL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 152 FMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDlqeantnqtsiqKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGq 231
Cdd:cd00625 82 LMLLTAALSAFFSNDATAVLLTPIVLALLRKLGL------------SPPVPLLLALAFAANIGGAATPIGNPPNLIIAS- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 232 ymqhfGYEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKyeEKVVQTIFVLASLLW 311
Cdd:cd00625 149 -----LSGLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKLTVLAEPLPARPLLK--KFLLLALLLLLLFVL 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 312 ITreFLLKKWEVTSSVADGTIAIFISillfiipakntekhRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLG 391
Cdd:cd00625 222 LF--FFLIPLGLIALLGALLLLLLLV--------------RGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWLA 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 392 EQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLS-----VAVGVHPLLLMAPAAMAANCAYMLPVGTP 466
Cdd:cd00625 286 ELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAppepaWLALALGSTLGGNLTLIGSLANLIPLGAA 365
|
410 420 430
....*....|....*....|....*....|....*
gi 446245312 467 PNAIIfgsgKISIKQMASVGFWVNLISAIIIILVV 501
Cdd:cd00625 366 ENAGV----GISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
78-502 |
1.05e-20 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 94.42 E-value: 1.05e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 78 IPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATG 157
Cdd:COG1055 23 LNRAVAALLGAALLLLLGVVSLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 158 FLSMFVSNTAAVMIMIPIGLAIIKEAhdlqeantnqtsiqKFE-KSLVLAIGYAGTIGGLGTLIGTPPLIILkGQYMQhf 236
Cdd:COG1055 103 LLSAFLDNDTTALLLTPVVLAIARRL--------------GLNpVPFLIAIVFAANIGGAATPIGNPTNIMI-ASAGG-- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 237 gyeISFAKWMIVGIPTVIVLLGITWLYLrYVAFRHDLKylpggqTLIKQKLDELGKMKYEEKVVQTIFVLASLL--WITR 314
Cdd:COG1055 166 ---LSFLDFLANLFPPSLVSLLVTLLVL-YLLFRKELP------AAPDLEDDPKEAIKDRRLLRISLLVLALLLvgFVLH 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 315 EFLlkkwEVTSSVADGTIAIFISILlfiipakntekhRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQL 394
Cdd:COG1055 236 SFL----GLPPALIALLGAAVLLLL------------ARVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELL 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 395 KSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLmapaamaancAYMLPVGTPPNAIIFGS 474
Cdd:COG1055 300 ASLTGGNLLLAALLILWLSAILSAVVDNVPLVAALLPLIPDLGATGNPEPLWL----------ALALGATLGGNLTPIGS 369
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 446245312 475 --------------GKISIKQMASVGFWVNLISAIIIILVVY 502
Cdd:COG1055 370 aanvivlgiaekkgIKISFGEFLKVGLPLTLLTLLIALLYLL 411
|
|
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
59-443 |
3.70e-13 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 71.13 E-value: 3.70e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 59 GVYVLaitlwIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTII 138
Cdd:cd01116 3 ITYAL-----IIFEKVHRTVAALAGALWLVILGLATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 139 NLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEahdlqeantnqtsIQKFEKSLVLAIGYAGTIGGLGT 218
Cdd:cd01116 78 KISKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEV-------------LGLNPVPVLISEVIAANIGGAAT 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 219 LIGTPPLIILkgqymqHFGYEISFAKWMIVGIPTVIVLLGITWLYLRYVaFRHDLKYLPGGQtlikQKLDELGKMKYEEK 298
Cdd:cd01116 145 LIGDPPNIMI------GSAAGLTFNDFLLHMLPSVVLALVVTFILLYFL-YRNILKAREEDV----LALAELEPKYPIKD 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 299 VV-----QTIFVLASLLWITREFLlkkwevtsSVADGTIAIFISILLFIIPAKNTEKHrriidweVAKELPWGVLILFGG 373
Cdd:cd01116 214 KVlllksLTILTLVIIGFVLHSPL--------GVSLGWIALLGALLLLLLADKLDFED-------VLSRVEWDTLLFFAG 278
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 374 GLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVH 443
Cdd:cd01116 279 LFVLVGGLEELGIIEWIAELLVGVILGRIAVAVILILWISALLSAFIDNIPVTATMIPIVKDLASQLGIP 348
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
52-264 |
9.55e-13 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 69.97 E-value: 9.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 52 PQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHT 131
Cdd:cd00625 203 PLLKKFLLLALLLLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLE 282
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 132 RVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLqeantnqtsiqkfeksLVLAIGYag 211
Cdd:cd00625 283 WLAELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAPPEPAW----------------LALALGS-- 344
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446245312 212 TIGGLGTLIGTPPLIILKGQYMQHfGYEISFAKWMIVGIPTVIVLLGITWLYL 264
Cdd:cd00625 345 TLGGNLTLIGSLANLIPLGAAENA-GVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
59-262 |
3.73e-11 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 64.79 E-value: 3.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 59 GVYVLAITLWIATWWIteAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTII 138
Cdd:COG0471 179 AIFALTVLLWITGSLH--GIPIAVVALLGAVLLLLTGVLTWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 139 NLI-GASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIikeahdLQEANTNQTsiqkfekSLVLAIGYAGTIGGLg 217
Cdd:COG0471 257 PLLgGLSPLLLLLLLALLTLLLTEFASNTATAALLLPIAISL------AQALGVNPL-------PLALAVAFAASCAFL- 322
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446245312 218 TLIGTPPLIILKGqymqhFGYeISFAKWMIVGIPTVIVLLGITWL 262
Cdd:COG0471 323 LPVGTPPNAIVYG-----SGY-YKFKDFLKVGLPLNLIGLVVLLL 361
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
78-267 |
4.13e-11 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 64.76 E-value: 4.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 78 IPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATG 157
Cdd:COG1055 240 LPPALIALLGAAVLLLLARVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSA 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 158 FLSMFVSNTAAVMIMIPIglaiIKEAHDLQEANTnqtsiqkfeksLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHfG 237
Cdd:COG1055 320 ILSAVVDNVPLVAALLPL----IPDLGATGNPEP-----------LWLALALGATLGGNLTPIGSAANVIVLGIAEKK-G 383
|
170 180 190
....*....|....*....|....*....|..
gi 446245312 238 YEISFAKWMIVGIPTVIV--LLGITWLYLRYV 267
Cdd:COG1055 384 IKISFGEFLKVGLPLTLLtlLIALLYLLLLYF 415
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
60-267 |
5.06e-10 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 61.45 E-value: 5.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 60 VYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIIN 139
Cdd:cd01115 193 VLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSIDWGIIFLFAGGIPLGKALESSGAAALIAEALIS 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 140 LI-GASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQEAntnqtsiqkfeksLVLAIGyAGTIGGLGT 218
Cdd:cd01115 273 LLgGLPPFAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEA-------------LLLAVA-IGASCAFML 338
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446245312 219 LIGTPP--LIILKGQYmqhfgyeiSFAKWMIVGIPTVIVLLGITWLYLRYV 267
Cdd:cd01115 339 PVGTPPnaIVLGPGGY--------KFSDFAKVGLPLSILSLVVSVTMIPLI 381
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
68-438 |
7.28e-10 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 60.75 E-value: 7.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 68 WIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGAStsK 147
Cdd:cd01117 1 LALGRVPGLRLDRWAIALLGAALMLLFGVISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILVKAGSP--R 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 148 ILLGFMV-ATGFLSMFVSNTAAVMIMIPIGLAIIKeahdlqeantnqtSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLI 226
Cdd:cd01117 79 RLLFLLVlLSGILSALLTNDTACLVFTPIVLELAR-------------VAGLPPIPLLLALATAANIGSAATPIGNPQNL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 227 ILKGQymqhfgYEISFAKWMIVGIPTVIVLLGITWLYLrYVAFRHDLkylpggqtlikqKLDELGKMKYEEKVVQTIFVL 306
Cdd:cd01117 146 LIASE------SGISFPFFLAAMAPLALLGLLLLLILL-LVLFPGEL------------KGLPLDKATKEEGVGARKLAV 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 307 ASLLWITREFLLKKwevtssVADGTIAIFISILLFIIPAKNTEKHRRiidwEVAKELPWGVLILFGGGLALAKGISESGL 386
Cdd:cd01117 207 KLLVLILLLLVAFL------ALLGVIPLWTAALVAAVLLLLTRLKPR----RVLKKVDWGLLLFFAGLFILVGGFAQGLP 276
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 446245312 387 AKWLGEQLKSLNGVSPILIVIvitifvLFLTEVTSNTATATMILPILATLSV 438
Cdd:cd01117 277 LEGLSRLLPLLDSVLSLFLVS------IGLSQLISNVPAVLLLLPFLPSADE 322
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
365-517 |
3.47e-09 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 58.80 E-value: 3.47e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 365 WGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHP 444
Cdd:cd00625 39 WETILLLFGMMILSAALEETGLFDRLAAKLARASKGSRRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPP 118
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446245312 445 LLLMAPAAMAANCAYML-PVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPL 517
Cdd:cd00625 119 VPLLLALAFAANIGGAAtPIGNPPNLIIASLSGLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDKL 192
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
365-505 |
1.13e-08 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 56.94 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 365 WGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHP 444
Cdd:pfam03600 39 SPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPP 118
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446245312 445 LLLMAPAAMAANCAYML-PVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVM 505
Cdd:pfam03600 119 SPLLIALAFAANIGGTAtPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLPLLLI 180
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
373-513 |
1.30e-08 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 56.70 E-value: 1.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 373 GGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAA 452
Cdd:COG0471 2 GGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKRSKFGSAL 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446245312 453 MAANC------AYMLPVGTPPNAIIfgSGKISIKQMASVGF----WVNLISAIIIILVVYYVMPIVLGIDI 513
Cdd:COG0471 82 LLPIAfaasigGMGTLIGTPPNLIA--AGLLEEATGIPISFfewmLVGLPVALVGLLLLWLVLYRLLPPEI 150
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
62-179 |
2.57e-07 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 52.70 E-value: 2.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 62 VLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERwnlhTRVALTIINLI 141
Cdd:pfam03600 208 LLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEK----TGLADALADAL 283
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 446245312 142 GASTSK--ILLGFMVATGFLSMFVSNTAAVMIMIPIGLAI 179
Cdd:pfam03600 284 GGLSGLlvALALILWLSALLSAFISNVPTAALMAPIIVGM 323
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
367-511 |
1.48e-06 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 50.28 E-value: 1.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 367 VLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLL 446
Cdd:cd01115 48 AVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLMLVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSR 127
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446245312 447 LMAPAAMAANCAYML-PVGTPPNAIIFGSGKISIKQMASVGFW--VNLISAIIIILVVYYVMPIVLGI 511
Cdd:cd01115 128 LLMPLAFAASIGGMLtLIGTPPNLVASGYLESLGGQGFSFFEFtpIGLPLLIIGLLYLWFIFRLAVLI 195
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
354-506 |
6.14e-05 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 45.50 E-value: 6.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446245312 354 IIDWE-VAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPI 432
Cdd:COG1055 41 VVSLEdALEAIDWNTILFLLGMMIIVAILDESGFFEWLAIKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPV 120
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446245312 433 LATLSVAVGVHPLLLMAPAAMAANCA-YMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMP 506
Cdd:COG1055 121 VLAIARRLGLNPVPFLIAIVFAANIGgAATPIGNPTNIMIASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFR 195
|
|
| |
