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Conserved domains on  [gi|446257041|ref|WP_000334896|]
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MULTISPECIES: hydrogenase maturation factor HybG [Gammaproteobacteria]

Protein Classification

HypC/HybG/HupF family hydrogenase formation chaperone( domain architecture ID 10013514)

HypC/HybG/HupF family hydrogenase formation chaperone such as Escherichia coli hydrogenase maturation factor HybG

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10413 PRK10413
hydrogenase maturation factor HybG;
1-82 2.76e-50

hydrogenase maturation factor HybG;


:

Pssm-ID: 182438  Cd Length: 82  Bit Score: 152.59  E-value: 2.76e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446257041  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDIT 80
Cdd:PRK10413  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMEYDIT 80


                ..
gi 446257041 81 SA 82
Cdd:PRK10413 81 SA 82
 
Name Accession Description Interval E-value
PRK10413 PRK10413
hydrogenase maturation factor HybG;
1-82 2.76e-50

hydrogenase maturation factor HybG;


Pssm-ID: 182438  Cd Length: 82  Bit Score: 152.59  E-value: 2.76e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446257041  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDIT 80
Cdd:PRK10413  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMEYDIT 80


                ..
gi 446257041 81 SA 82
Cdd:PRK10413 81 SA 82
HypC COG0298
Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein ...
 1-75 2.23e-28

Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440067  Cd Length: 78  Bit Score: 96.75  E-value: 2.23e-28
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446257041  1 MCIGVPGQVLAVGEDihQLAQVEVCGIKRDVNIALICEgnpaDLLGQWVLVHVGFAMSIIDEDEAKATLDALRQM 75
Cdd:COG0298   1 MCLAIPGKVVEILDG--DTALVDVGGVRREVSLALVPE----VKVGDYVLVHVGFAIEKIDEEEAEETLELLEEL 69
hypC_hupF TIGR00074
hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for ...
 1-82 3.36e-26

hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for a hydrogenase large subunit, holding the precursor form before metallocenter nickel incorporation. [SS 12/31/03] More recently proposed additional function is to shuttle the iron atom that has been liganded at the HypC/HypD complex to the precursor of the large hydrogenase (HycE) subunit. . Added metallochaperone and protein mod GO terms. [Protein fate, Protein folding and stabilization, Protein fate, Protein modification and repair]


Pssm-ID: 129184  Cd Length: 76  Bit Score: 91.28  E-value: 3.36e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446257041   1 MCIGVPGQVLAVGEDIhqlAQVEVCGIKRDVNIALICEgnpaDLLGQWVLVHVGFAMSIIDEDEAKATLDALRQM-DYDI 79
Cdd:TIGR00074  1 MCIAIPGQVVEIDENI---ALVEFCGIKRDVSLDLVGE----VKVGDYVLVHVGFAISVLDEEEARETLDALQELfDAVE 73


                 ...
gi 446257041  80 TSA 82
Cdd:TIGR00074 74 EGD 76
HupF_HypC pfam01455
HupF/HypC family;
2-72 6.83e-24

HupF/HypC family;


Pssm-ID: 460218  Cd Length: 64  Bit Score: 85.11  E-value: 6.83e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446257041   2 CIGVPGQVLAVGEDIhqlAQVEVCGIKRDVNIALICEGNPadllGQWVLVHVGFAMSIIDEDEAKATLDAL 72
Cdd:pfam01455  1 CLAIPGKVVEIDDEM---AVVDFGGVRREVSLALVPEVKV----GDYVLVHAGFAIEKIDEEEAEETLALL 64
 
Name Accession Description Interval E-value
PRK10413 PRK10413
hydrogenase maturation factor HybG;
1-82 2.76e-50

hydrogenase maturation factor HybG;


Pssm-ID: 182438  Cd Length: 82  Bit Score: 152.59  E-value: 2.76e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446257041  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDIT 80
Cdd:PRK10413  1 MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMEYDIT 80


                ..
gi 446257041 81 SA 82
Cdd:PRK10413 81 SA 82
HypC COG0298
Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein ...
 1-75 2.23e-28

Hydrogenase maturation factor HybG, HypC/HupF family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440067  Cd Length: 78  Bit Score: 96.75  E-value: 2.23e-28
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446257041  1 MCIGVPGQVLAVGEDihQLAQVEVCGIKRDVNIALICEgnpaDLLGQWVLVHVGFAMSIIDEDEAKATLDALRQM 75
Cdd:COG0298   1 MCLAIPGKVVEILDG--DTALVDVGGVRREVSLALVPE----VKVGDYVLVHVGFAIEKIDEEEAEETLELLEEL 69
hypC_hupF TIGR00074
hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for ...
 1-82 3.36e-26

hydrogenase assembly chaperone HypC/HupF; This protein is suggested by act as a chaperone for a hydrogenase large subunit, holding the precursor form before metallocenter nickel incorporation. [SS 12/31/03] More recently proposed additional function is to shuttle the iron atom that has been liganded at the HypC/HypD complex to the precursor of the large hydrogenase (HycE) subunit. . Added metallochaperone and protein mod GO terms. [Protein fate, Protein folding and stabilization, Protein fate, Protein modification and repair]


Pssm-ID: 129184  Cd Length: 76  Bit Score: 91.28  E-value: 3.36e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446257041   1 MCIGVPGQVLAVGEDIhqlAQVEVCGIKRDVNIALICEgnpaDLLGQWVLVHVGFAMSIIDEDEAKATLDALRQM-DYDI 79
Cdd:TIGR00074  1 MCIAIPGQVVEIDENI---ALVEFCGIKRDVSLDLVGE----VKVGDYVLVHVGFAISVLDEEEARETLDALQELfDAVE 73


                 ...
gi 446257041  80 TSA 82
Cdd:TIGR00074 74 EGD 76
PRK10409 PRK10409
HypC/HybG/HupF family hydrogenase formation chaperone;
1-75 9.11e-25

HypC/HybG/HupF family hydrogenase formation chaperone;


Pssm-ID: 182435  Cd Length: 90  Bit Score: 88.32  E-value: 9.11e-25
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446257041  1 MCIGVPGQVLAVGEDihqLAQVEVCGIKRDVNIALI--CEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQM 75
Cdd:PRK10409  1 MCIGVPGQIRTIDGN---QAKVDVCGIQRDVDLTLVgsCDENGQPRVGQWVLVHVGFAMSVINEAEARDTLDALQNM 74
HupF_HypC pfam01455
HupF/HypC family;
2-72 6.83e-24

HupF/HypC family;


Pssm-ID: 460218  Cd Length: 64  Bit Score: 85.11  E-value: 6.83e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446257041   2 CIGVPGQVLAVGEDIhqlAQVEVCGIKRDVNIALICEGNPadllGQWVLVHVGFAMSIIDEDEAKATLDAL 72
Cdd:pfam01455  1 CLAIPGKVVEIDDEM---AVVDFGGVRREVSLALVPEVKV----GDYVLVHAGFAIEKIDEEEAEETLALL 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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