NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|446286710|ref|WP_000364565|]
View 

MULTISPECIES: DNA polymerase III subunit delta' [Streptococcus]

Protein Classification

DNA polymerase III subunit delta'( domain architecture ID 11482674)

DNA polymerase III subunit delta' interacts with the delta and gamma subunits and is part of the clamp-loading complex, which assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 1-286 1.41e-177

DNA polymerase III subunit delta'; Validated


:

Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 491.07  E-value: 1.41e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   1 MDLKRTQPKLLEKFNTILQSDRMSHAYLFSGNFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQ 80
Cdd:PRK07276   1 MDLKQKQPKVFQRFQTILEQDRLNHAYLFSGDFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  81 GQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF 160
Cdd:PRK07276  81 GQVIKTDTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 161 PKQLDMLVHQAEQAGLLKSQASLLAQVADDPKHLEILLTNKKLLDYLNLSQQFVTTLAKDRQTAYLEVSRLTSQVVDKND 240
Cdd:PRK07276 161 PKNEAYLIQLLEQKGLLKTQAELLAKLAQSTSEAEKLAQNKKFLELIDQAERFVTILLKDKDEAYLQVARLVQLADEKEE 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 446286710 241 QAFVFQWLTIMLAKE----GQLYDLENTYRAQQMWKSNVSFQNSLEYMVL 286
Cdd:PRK07276 241 QDQVLTLLTLLLAQErmqvNVRTQLEAVYQARKMWQSNVSFQNALEYMVL 290
 
Name Accession Description Interval E-value
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 1-286 1.41e-177

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 491.07  E-value: 1.41e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   1 MDLKRTQPKLLEKFNTILQSDRMSHAYLFSGNFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQ 80
Cdd:PRK07276   1 MDLKQKQPKVFQRFQTILEQDRLNHAYLFSGDFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  81 GQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF 160
Cdd:PRK07276  81 GQVIKTDTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 161 PKQLDMLVHQAEQAGLLKSQASLLAQVADDPKHLEILLTNKKLLDYLNLSQQFVTTLAKDRQTAYLEVSRLTSQVVDKND 240
Cdd:PRK07276 161 PKNEAYLIQLLEQKGLLKTQAELLAKLAQSTSEAEKLAQNKKFLELIDQAERFVTILLKDKDEAYLQVARLVQLADEKEE 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 446286710 241 QAFVFQWLTIMLAKE----GQLYDLENTYRAQQMWKSNVSFQNSLEYMVL 286
Cdd:PRK07276 241 QDQVLTLLTLLLAQErmqvNVRTQLEAVYQARKMWQSNVSFQNALEYMVL 290
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 7-162 1.17e-79

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 237.88  E-value: 1.17e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710    7 QPKLLEKFNTILQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLI 84
Cdd:pfam13177   2 QPEAIQLLQNSLENGRLSHAYLFSGpeGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQSI 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446286710   85 KTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:pfam13177  82 KIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 11-188 5.62e-63

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 196.69  E-value: 5.62e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   11 LEKFNTILQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLIKTET 88
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVgkELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSIKVDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   89 IKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF-PKQLDML 167
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFpPLSEEAL 160

                         170       180
                  ....*....|....*....|.
gi 446286710  168 VHQAEQAGLLKSQASLLAQVA 188
Cdd:TIGR00678 161 LQWLIRQGISEEAAELLLALA 181
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
18-189 9.48e-50

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 167.29  E-value: 9.48e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLIKTETIKELTKD 95
Cdd:COG2812   26 LASGRLAHAYLFTGPRGVgkTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAEASNIGVDDIRELIEK 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  96 FSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF----PKQL-DMLVHQ 170
Cdd:COG2812  106 VSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFrrlpPEEIaEHLAKI 185

                        170       180
                 ....*....|....*....|.
gi 446286710 171 AEQAGLL--KSQASLLAQVAD 189
Cdd:COG2812  186 AEREGIEiePEALALIARAAD 206
 
Name Accession Description Interval E-value
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 1-286 1.41e-177

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 491.07  E-value: 1.41e-177
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   1 MDLKRTQPKLLEKFNTILQSDRMSHAYLFSGNFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQ 80
Cdd:PRK07276   1 MDLKQKQPKVFQRFQTILEQDRLNHAYLFSGDFASFEMALFLAQSLFCEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  81 GQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF 160
Cdd:PRK07276  81 GQVIKTDTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 161 PKQLDMLVHQAEQAGLLKSQASLLAQVADDPKHLEILLTNKKLLDYLNLSQQFVTTLAKDRQTAYLEVSRLTSQVVDKND 240
Cdd:PRK07276 161 PKNEAYLIQLLEQKGLLKTQAELLAKLAQSTSEAEKLAQNKKFLELIDQAERFVTILLKDKDEAYLQVARLVQLADEKEE 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 446286710 241 QAFVFQWLTIMLAKE----GQLYDLENTYRAQQMWKSNVSFQNSLEYMVL 286
Cdd:PRK07276 241 QDQVLTLLTLLLAQErmqvNVRTQLEAVYQARKMWQSNVSFQNALEYMVL 290
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 7-162 1.17e-79

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 237.88  E-value: 1.17e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710    7 QPKLLEKFNTILQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLI 84
Cdd:pfam13177   2 QPEAIQLLQNSLENGRLSHAYLFSGpeGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEGQSI 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446286710   85 KTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:pfam13177  82 KIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKP 159
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 11-188 5.62e-63

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 196.69  E-value: 5.62e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   11 LEKFNTILQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLIKTET 88
Cdd:TIGR00678   1 YQQLKRALEKGRLAHAYLFTGPEGVgkELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQSIKVDQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   89 IKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF-PKQLDML 167
Cdd:TIGR00678  81 VRELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFpPLSEEAL 160

                         170       180
                  ....*....|....*....|.
gi 446286710  168 VHQAEQAGLLKSQASLLAQVA 188
Cdd:TIGR00678 161 LQWLIRQGISEEAAELLLALA 181
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 1-286 1.19e-61

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 197.84  E-value: 1.19e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   1 MDLKRTQPKLLEKFNTILQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIE 78
Cdd:PRK08058   5 EQLTALQPVVVKMLQNSIAKNRLSHAYLFEGAKGTgkKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVA 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  79 PQGQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIF 158
Cdd:PRK08058  85 PDGQSIKKDQIRYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQVV 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 159 RF-PKQLDMLVHQAEQAGLLKSQASLLAQVADDPKHLEIL-------------------LTNKKLLDYLNLSQQFVTtLA 218
Cdd:PRK08058 165 EFrPLPPESLIQRLQEEGISESLATLLAGLTNSVEEALALseddwfaqaralviklyeaLHEKDLQSFVFVQEKWMP-LF 243

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 219 KDRQtaYLEVS----------RLTSQVVDKNDQAFV-----FQWLTIMLAKEGQLYDLENTYRAQQMWKSNVSFQNSLEY 283
Cdd:PRK08058 244 KEKD--QQQLGldlllliyrdLLYLQLGEEDRLVFReqkemLQQLALSYSQQQIVAALELILEAKRRLNSNVNFQLVMEQ 321


                 ...
gi 446286710 284 MVL 286
Cdd:PRK08058 322 LVL 324
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
18-189 9.48e-50

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 167.29  E-value: 9.48e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLIKTETIKELTKD 95
Cdd:COG2812   26 LASGRLAHAYLFTGPRGVgkTTLARILAKALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAEASNIGVDDIRELIEK 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  96 FSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF----PKQL-DMLVHQ 170
Cdd:COG2812  106 VSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFrrlpPEEIaEHLAKI 185

                        170       180
                 ....*....|....*....|.
gi 446286710 171 AEQAGLL--KSQASLLAQVAD 189
Cdd:COG2812  186 AEREGIEiePEALALIARAAD 206
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
7-286 2.65e-47

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 159.76  E-value: 2.65e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   7 QPKLLEKFNTILQSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRaCRLIANGEFSDVKIIEPQ--GQ 82
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPpgIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELNPEekSD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  83 LIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:COG0470   80 QIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 163 -QLDMLVHQAEQAGLLKSQASLLAQVAD-DPkhleilLTNKKLLDYLNLSQQFVTTLAK----DRQTAYLEvsrltsqVV 236
Cdd:COG0470  160 pSEEEALAWLREEGVDEDALEAILRLAGgDP------RAAINLLQALAGRKELLEDLAAllsrDRALELLD-------AL 226

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446286710 237 DKNDQAFVFQWLT--------IMLAKEGQLYDLENTYRAQQMWKSNVSFQNSLEYMVL 286
Cdd:COG0470  227 LKAEALELLDWLLkwlldnlpLEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLA 284
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
 15-248 1.43e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 111.33  E-value: 1.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  15 NTILQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQ--GQLIKTETIK 90
Cdd:PRK05707  13 QQLAGRGRHPHAYLLHGpaGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLEPEeaDKTIKVDQVR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  91 ELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPkqldmLVHQ 170
Cdd:PRK05707  93 ELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACP-----LPSN 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 171 AEqagllkSQASLLAQVAD-DPKHLEILLT----------NKKLLDYLNLSQQFVTT---LAKDRQTAylevsrltSQVV 236
Cdd:PRK05707 168 EE------SLQWLQQALPEsDERERIELLTlaggsplralQLHEQGVREQRARVLDGvkkLLKQQQSA--------SQLA 233

                        250
                 ....*....|....*
gi 446286710 237 D---KNDQAFVFQWL 248
Cdd:PRK05707 234 EswlKVPLLLLFDWF 248
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
 21-161 6.96e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 90.31  E-value: 6.96e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  21 DRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSG-LPCQECRACRLIANGEFSDVKIIEPQGQ---------LIKTET 88
Cdd:PRK08699  18 ERRPNAWLFAGkkGIGKTAFARFAAQALLCETPAPGhKPCGECMSCHLFGQGSHPDFYEITPLSDepengrkllQIKIDA 97

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446286710  89 IKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFP 161
Cdd:PRK08699  98 VREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLP 170
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 7-286 1.31e-20

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 91.69  E-value: 1.31e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   7 QPKLLEKFNTILQSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQlI 84
Cdd:PRK08691  21 QEHVVKALQNALDEGRLHHAYLLTGTrgVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAGRYVDLLEIDAASN-T 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  85 KTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF---- 160
Cdd:PRK08691 100 GIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTVLSRCLQFVLrnmt 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 161 PKQL-DMLVHqaeqagLLKSQasllaQVADDPKHLEIL--LTNKKLLDYLNLSQQFVT----TLAKDrqtaylEVSRLTS 233
Cdd:PRK08691 180 AQQVaDHLAH------VLDSE-----KIAYEPPALQLLgrAAAGSMRDALSLLDQAIAlgsgKVAEN------DVRQMIG 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446286710 234 QVvdknDQAFVFQWLTIMLAKEGQLYdlenTYRAQQMWKSNVSFQNSL-EYMVL 286
Cdd:PRK08691 243 AV----DKQYLYELLTGIINQDGAAL----LAKAQEMAACAVGFDNALgELAIL 288
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 18-216 4.20e-19

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 86.79  E-value: 4.20e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQ-SGLPCQECRACRLIANGefSDVKIIE-PQGQLIKTETIKELT 93
Cdd:PRK14950  32 IAEGRVAHAYLFTGprGVGKTSTARILAKAVNCTTNDpKGRPCGTCEMCRAIAEG--SAVDVIEmDAASHTSVDDAREII 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  94 KDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPKQ--LDMLVH-- 169
Cdd:PRK14950 110 ERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSRCQRFDFHRHsvADMAAHlr 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 446286710 170 ---QAEQAGLLKSQASLLAQVAddpkhleilltNKKLLDYLNLSQQFVTT 216
Cdd:PRK14950 190 kiaAAEGINLEPGALEAIARAA-----------TGSMRDAENLLQQLATT 228
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
 18-189 4.95e-19

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 86.43  E-value: 4.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKrQSGLPCQECRACRLIANGEFSDVKIIEPQGQlIKTETIKELTKD 95
Cdd:PRK14963  30 LRQGRLGHAYLFSGprGVGKTTTARLIAMAVNCSG-EDPKPCGECESCLAVRRGAHPDVLEIDAASN-NSVEDVRDLREK 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  96 FSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK--------QLDML 167
Cdd:PRK14963 108 VLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQHFRFRRlteeeiagKLRRL 187

                        170       180
                 ....*....|....*....|....*.
gi 446286710 168 VH----QAEQAGLLksqasLLAQVAD 189
Cdd:PRK14963 188 LEaegrEAEPEALQ-----LVARLAD 208
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
 18-160 6.74e-19

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 85.97  E-value: 6.74e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVkiIEPQGQliKTETIKELTKD 95
Cdd:PRK14962  30 LKKNSISHAYIFAGprGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEGTFMDV--IELDAA--SNRGIDEIRKI 105

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446286710  96 FSRSGF---EGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF 160
Cdd:PRK14962 106 RDAVGYrpmEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRCQVIEF 173
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
 7-160 1.01e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 84.18  E-value: 1.01e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   7 QPKLLEKFNTILQSDRMSHAYLFSG------NFASLdmalylaqsQFCEKRQSGLPCQECRACRLIaNGEFSDVKIIEP- 79
Cdd:PRK07399   9 QPLAIELLTAAIKQNRIAPAYLFAGpegvgrKLAAL---------CFIEGLLSQGSPSKNIRRRLE-EGNHPDLLWVEPt 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  80 ---QGQL------------------IKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPqSSSYVI 138
Cdd:PRK07399  79 yqhQGKLitaseaeeaglkrkappqIRLEQIREIKRFLSRPPLEAPRKVVVIEDAETMNEAAANALLKTLEEP-GNGTLI 157

                        170       180
                 ....*....|....*....|..
gi 446286710 139 LLTNDENNVLPTIKSRTQIFRF 160
Cdd:PRK07399 158 LIAPSPESLLPTIVSRCQIIPF 179
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
 48-165 1.97e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 82.57  E-value: 1.97e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  48 CEKRQSglPCQECRACRLIANGEFSDVKIIEPQGQLIKTETIKELTKDFSRSGFEGKS-QVFIIKDCEKMHVNAANSLLK 126
Cdd:PRK05818  33 CTKANG--FCKTCESCLKILNGKYNDFYLIFDQKNPIKKEDALSIINKLNRPSVESNGkKIYIIYGIEKLNKQSANSLLK 110

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 446286710 127 FIEEPQSSSYVILLTNDENNVLPTIKSRTQIF-------RFPKQLD 165
Cdd:PRK05818 111 LIEEPPKNTYGIFTTRNENNILNTILSRCVQYvvlskekKVPFKVE 156
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
 21-188 2.37e-18

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 84.49  E-value: 2.37e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  21 DRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSD-VKIIEPQGQLIktETIKELTKDFS 97
Cdd:PRK14953  35 QRVSHAYIFAGprGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSFPDlIEIDAASNRGI--DDIRALRDAVS 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  98 RSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK--------------- 162
Cdd:PRK14953 113 YTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRFIFSKptkeqikeylkricn 192

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 446286710 163 ---------QLDMLVHQAEqaGLLKSQASLLAQVA 188
Cdd:PRK14953 193 eekieyeekALDLLAQASE--GGMRDAASLLDQAS 225
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
 14-159 2.05e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 80.46  E-value: 2.05e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  14 FNTILQSDRMSHAYLFSGNFA---SLdMALYLAqSQFCEKRQsglpcqecracrliaNGEFSDV---KIIEPQGqlIKTE 87
Cdd:PRK05564  16 IKNSIIKNRFSHAHIIVGEDGigkSL-LAKEIA-LKILGKSQ---------------QREYVDIiefKPINKKS--IGVD 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446286710  88 TIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFR 159
Cdd:PRK05564  77 DIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYK 148
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 19-162 4.61e-17

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 80.88  E-value: 4.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  19 QSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVkiIEPQGQLIK-TETIKELTKD 95
Cdd:PRK14959  33 QENRVAPAYLFSGTrgVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQGMHVDV--VEIDGASNRgIDDAKRLKEA 110

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446286710  96 FSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK14959 111 IGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQHFTFTR 177
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
 23-157 5.81e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 79.96  E-value: 5.81e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  23 MSHAYLFSGNFAS--LDMALYLAQSQFCEKRQSGlPCQECRACRLIANGEFSDVKIIEPQGQLIKTETIKELTKDFSRSG 100
Cdd:PRK07940  35 MTHAWLFTGPPGSgrSVAARAFAAALQCTDPDEP-GCGECRACRTVLAGTHPDVRVVAPEGLSIGVDEVRELVTIAARRP 113

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446286710 101 FEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQI 157
Cdd:PRK07940 114 STGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRH 170
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
 16-250 6.41e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 79.00  E-value: 6.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  16 TILQSDRMSHAYLFSGNF-ASLDMALYLAQSQFCEKRQSGLPCQEcracrLIANGEFSDVKiiepQGQLIKTETIKELtK 94
Cdd:PRK07132  10 NSATQNKISHSFLLKSNYnEDIDEKILYFLNKFNNLQITNLNEQE-----LPANIILFDIF----DKDLSKSEFLSAI-N 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  95 DFSRSGFE-GKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF--PKQLDMLVHQA 171
Cdd:PRK07132  80 KLYFSSFVqSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVkePDQQKILAKLL 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446286710 172 EQaGLLKSQASLLAQVADDPKHLEILLTNkkllDYLNLSQQFVTTLAKDRQTAYLEVSRLTSqVVDKNDQAFVFQWLTI 250
Cdd:PRK07132 160 SK-NKEKEYNWFYAYIFSNFEQAEKYINK----ESENLLKKFEEALNKSLKEKYELILFLNK-KLTKENALFLLKLLKF 232
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
 42-156 8.41e-17

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 79.01  E-value: 8.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  42 LAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEP-QGQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNA 120
Cdd:PRK06871  44 LAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILEPiDNKDIGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAA 123

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446286710 121 ANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQ 156
Cdd:PRK06871 124 ANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
 21-191 1.80e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 78.26  E-value: 1.80e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  21 DRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQS-GLPCQECRACRLIANGEFSDVKIIEPQ----------------- 80
Cdd:PRK06964  18 ARLPHALLLHGQagIGKLDFAQHLAQGLLCETPQPdGEPCGTCAACNWFAQGNHPDYRIVRPEalaaeapgaadeakead 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  81 -----------GQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLP 149
Cdd:PRK06964  98 adeggkktkapSKEIKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLP 177

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 446286710 150 TIKSRTqifrfpKQLDMLVHQAEQA-GLLKSQ-----ASLLAQVADDP 191
Cdd:PRK06964 178 TILSRC------RQFPMTVPAPEAAaAWLAAQgvadaDALLAEAGGAP 219
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
 42-239 2.64e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 77.54  E-value: 2.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  42 LAQSQFCEKRQSGlPCQECRACRLIANGEFSDVKIIEPQ--GQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVN 119
Cdd:PRK06090  45 FSRALLCQNYQSE-ACGFCHSCELMQSGNHPDLHVIKPEkeGKSITVEQIRQCNRLAQESSQLNGYRLFVIEPADAMNES 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 120 AANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF-PKQLDMLVHQAEQAGlLKSQASLLAQVADDPKHLEILL 198
Cdd:PRK06090 124 ASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVtPPSTAQAMQWLKGQG-ITVPAYALKLNMGSPLKTLAMM 202

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 446286710 199 TNKKLLDYLNLSQQFVTTLAKDrQTAYLEVSRLTSQVVDKN 239
Cdd:PRK06090 203 KEGGLEKYHKLERQLVDALSGP-VSDQLKCASLIAADPLTH 242
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 18-188 1.28e-15

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 76.70  E-value: 1.28e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQlIKTETIKELTKD 95
Cdd:PRK14965  32 IDTGRVAHAFLFTGarGVGKTSTARILAKALNCEQGLTAEPCNVCPPCVEITEGRSVDVFEIDGASN-TGVDDIRELREN 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  96 F----SRSGFegksQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF-----PKQLDM 166
Cdd:PRK14965 111 VkylpSRSRY----KIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPITILSRCQRFDFrriplQKIVDR 186

                        170       180
                 ....*....|....*....|..
gi 446286710 167 LVHQAEQAGLLKSQASlLAQVA 188
Cdd:PRK14965 187 LRYIADQEGISISDAA-LALVA 207
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
 18-160 3.43e-15

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 75.19  E-value: 3.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGefSDVKIIEPQG---------QLIKT 86
Cdd:PRK06647  32 IESNKIANAYIFSGprGVGKTSSARAFARCLNCVNGPTPMPCGECSSCKSIDND--NSLDVIEIDGasntsvqdvRQIKE 109

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446286710  87 ETIkeltkdFSRSGfeGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF 160
Cdd:PRK06647 110 EIM------FPPAS--SRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQHFNF 175
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
 18-162 1.08e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 73.83  E-value: 1.08e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLiKTETIKELTKD 95
Cdd:PRK14956  34 LKSGKIGHAYIFFGprGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKGISSDVLEIDAASNR-GIENIRELRDN 112

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446286710  96 FSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK14956 113 VKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQDFIFKK 179
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
 7-180 2.48e-14

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 72.84  E-value: 2.48e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   7 QPKLLEKFNTILQSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQlI 84
Cdd:PRK14958  21 QAPVVRALSNALDQQYLHHAYLFTGTrgVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEGRFPDLFEVDAASR-T 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  85 KTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFpKQL 164
Cdd:PRK14958 100 KVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRCLQFHL-AQL 178

                        170
                 ....*....|....*.
gi 446286710 165 DMLVHQAEQAGLLKSQ 180
Cdd:PRK14958 179 PPLQIAAHCQHLLKEE 194
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
18-169 1.06e-13

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 70.76  E-value: 1.06e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG-----NFASldmALYLAQSQFC--EKRQSGLPCQECRACRLIANGEFSDVkiIEpqgqlIKT---- 86
Cdd:PRK14948  32 LISNRIAPAYLFTGprgtgKTSS---ARILAKSLNClnSDKPTPEPCGKCELCRAIAAGNALDV--IE-----IDAasnt 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  87 --ETIKELTKdfsRSGF---EGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFP 161
Cdd:PRK14948 102 gvDNIRELIE---RAQFapvQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTDPQRVLPTIISRCQRFDFR 178


                 ....*....
gi 446286710 162 K-QLDMLVH 169
Cdd:PRK14948 179 RiPLEAMVQ 187
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
 18-184 2.15e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 69.80  E-value: 2.15e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCEKR-QSGLPCQECRACRLIANGEFSDVkiIEPQGQLIK-TETIKELT 93
Cdd:PRK06305  33 LRFNRAAHAYLFSGIRGTgkTTLARIFAKALNCQNPtEDQEPCNQCASCKEISSGTSLDV--LEIDGASHRgIEDIRQIN 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  94 KDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIF---RFPKQ--LDMLV 168
Cdd:PRK06305 111 ETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILSRCQKMhlkRIPEEtiIDKLA 190

                        170
                 ....*....|....*.
gi 446286710 169 HQAEQAGLLKSQASLL 184
Cdd:PRK06305 191 LIAKQEGIETSREALL 206
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
 18-162 3.88e-13

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 69.29  E-value: 3.88e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDvkIIEPQG-QLIKTETIKELTK 94
Cdd:PRK08451  30 LDNNRLAHAYLFSGLRGSgkTSSARIFARALVCEQGPSSTPCDTCIQCQSALENRHID--IIEMDAaSNRGIDDIRELIE 107

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  95 DFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPqsSSYV--ILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK08451 108 QTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEP--PSYVkfILATTDPLKLPATILSRTQHFRFKQ 175
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
18-154 1.17e-12

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 67.77  E-value: 1.17e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQlIKTETIKELTKD 95
Cdd:PRK14960  31 LERGRLHHAYLFTGTrgVGKTTIARILAKCLNCETGVTSTPCEVCATCKAVNEGRFIDLIEIDAASR-TKVEDTRELLDN 109

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446286710  96 FSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSR 154
Cdd:PRK14960 110 VPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISR 168
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
7-160 1.46e-12

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 67.60  E-value: 1.46e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   7 QPKLLEKFNTILQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIE----PQ 80
Cdd:PRK14952  18 QEHVTEPLSSALDAGRINHAYLFSGprGCGKTSSARILARSLNCAQGPTATPCGVCESCVALAPNGPGSIDVVEldaaSH 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  81 GQLIKTETIKEltkdfsRSGF---EGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQI 157
Cdd:PRK14952  98 GGVDDTRELRD------RAFYapaQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTHH 171


                 ...
gi 446286710 158 FRF 160
Cdd:PRK14952 172 YPF 174
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 19-154 1.08e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 64.32  E-value: 1.08e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  19 QSDRMSHAYLFSGNFASLDMALYLAQSQF--CEKRQSGLPCQECRACRLIANGEFSDVKIIEPQG--QLIKTETIKELTK 94
Cdd:PRK07993  19 QAGRGHHALLIQALPGMGDDALIYALSRWlmCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLTPEKgkSSLGVDAVREVTE 98

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  95 DFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSR 154
Cdd:PRK07993  99 KLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSR 158
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
 84-273 2.40e-11

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 63.13  E-value: 2.40e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  84 IKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFpKQ 163
Cdd:PRK09112 121 ITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCQPISL-KP 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 164 LDmlvhqaeQAGLLKSQASLLAQVADDPKHLEILLTNKK--------LLDY--LNLSQQFVTTLAKDRQTAYlEVSRLtS 233
Cdd:PRK09112 200 LD-------DDELKKALSHLGSSQGSDGEITEALLQRSKgsvrkallLLNYggLEIIATIDQLLAGSGPDAR-KAHKL-A 270

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446286710 234 QVVDKNDQAFVFQW-----------LTIMLAKEGQLYDLEntyRAQQMWKS 273
Cdd:PRK09112 271 DALSGRESEVQFDFfrdhlldrimaEARRAAEAGDLALAE---RLARLWSE 318
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
 22-159 2.66e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 63.29  E-value: 2.66e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  22 RMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQlIKTETIKELTKDFSRS 99
Cdd:PRK14961  36 RIHHAWLLSGtrGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEKGLCLDLIEIDAASR-TKVEEMREILDNIYYS 114

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 100 GFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFR 159
Cdd:PRK14961 115 PSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRCLQFK 174
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
 18-154 3.02e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 63.61  E-value: 3.02e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDvkIIEPQGQL-IKTETIKELTK 94
Cdd:PRK14969  32 LEQQRLHHAYLFTGTrgVGKTTLARILAKSLNCETGVTATPCGVCSACLEIDSGRFVD--LIEVDAASnTQVDAMRELLD 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  95 DFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSR 154
Cdd:PRK14969 110 NAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSR 169
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
 15-160 4.21e-11

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 62.97  E-value: 4.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  15 NTILQsDRMSHAYLFSGN-----------FASldmALYlaqsqfCEKRQSGLPCQECRACRLIANGEFSDVkiIEpqgql 83
Cdd:PRK05563  30 NAIKQ-GKISHAYLFSGPrgtgktsaakiFAK---AVN------CLNPPDGEPCNECEICKAITNGSLMDV--IE----- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  84 I------KTETIKELTKD--FSRSgfEGKSQVFIIkDCEKMHVNAA-NSLLKFIEEPqsSSYV--ILLTNDENNVLPTIK 152
Cdd:PRK05563  93 IdaasnnGVDEIRDIRDKvkYAPS--EAKYKVYII-DEVHMLSTGAfNALLKTLEEP--PAHVifILATTEPHKIPATIL 167


                 ....*...
gi 446286710 153 SRTQIFRF 160
Cdd:PRK05563 168 SRCQRFDF 175
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
 18-154 8.35e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 62.02  E-value: 8.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQLIKTETiKELTKD 95
Cdd:PRK14957  32 LETQKVHHAYLFTGTrgVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINNNSFIDLIEIDAASRTGVEET-KEILDN 110

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446286710  96 FSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSR 154
Cdd:PRK14957 111 IQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSR 169
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
 18-170 1.28e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 61.13  E-value: 1.28e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCekrQSGLPCQECRACRLIANGEFSDVKIIE----PQGQLIKTE---- 87
Cdd:PRK08769  20 LDAGRLGHGLLICGpeGLGKRAVALALAEHVLA---SGPDPAAAQRTRQLIAAGTHPDLQLVSfipnRTGDKLRTEivie 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  88 TIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQI--FRFP---K 162
Cdd:PRK08769  97 QVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRleFKLPpahE 176


                 ....*...
gi 446286710 163 QLDMLVHQ 170
Cdd:PRK08769 177 ALAWLLAQ 184
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
 7-172 4.93e-10

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 59.83  E-value: 4.93e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710   7 QPKLLEKFNTILQSDRMSHAYLFSGNFAS--LDMALYLAQSQFCE-KRQSGLPCQECracrlIANGEFSdVKIIEPQGQL 83
Cdd:PRK07133  23 QDHIVQTLKNIIKSNKISHAYLFSGPRGTgkTSVAKIFANALNCShKTDLLEPCQEC-----IENVNNS-LDIIEMDAAS 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  84 -IKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK07133  97 nNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIPLTILSRVQRFNFRR 176

                        170
                 ....*....|.
gi 446286710 163 -QLDMLVHQAE 172
Cdd:PRK07133 177 iSEDEIVSRLE 187
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
 84-175 1.05e-09

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 58.50  E-value: 1.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  84 IKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRF-PK 162
Cdd:PRK07471 121 ITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIRSRCRKLRLrPL 200

                         90
                 ....*....|...
gi 446286710 163 QLDMLVHQAEQAG 175
Cdd:PRK07471 201 APEDVIDALAAAG 213
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 18-231 1.19e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 58.80  E-value: 1.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEK--------RQSGLPCQECRACRLIANGEFSDVKIIEPQGQlIKTE 87
Cdd:PRK14954  32 LRMDRVGHGYIFSGlrGVGKTTAARVFAKAVNCQRmiddpvylQEVTEPCGECESCRDFDAGTSLNISEFDAASN-NSVD 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  88 TIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK----- 162
Cdd:PRK14954 111 DIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFKRiplde 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710 163 ---QLDM---------------LVHQAEQAGLLKSQaSLLAQV---ADDPKHLEILLTNK--KLLDYLNLSQQFVTT--L 217
Cdd:PRK14954 191 iqsQLQMicraegiqidadalqLIARKAQGSMRDAQ-SILDQViafSVGSEAEKVIAYQGvaELLNYIDDEQFFDVTdaI 269

                        250
                 ....*....|....
gi 446286710 218 AKDRQTAYLEVSRL 231
Cdd:PRK14954 270 AENDAVKMLEVARF 283
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
15-160 1.88e-09

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 58.25  E-value: 1.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  15 NTIlQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQS-GLPCQECRACR------------LIA--NGEFSDVKii 77
Cdd:PRK14971  31 NAI-ATNKLAHAYLFCGprGVGKTTCARIFAKTINCQNLTAdGEACNECESCVafneqrsyniheLDAasNNSVDDIR-- 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  78 epqgQLIKTETIKELTkdfsrsgfeGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQI 157
Cdd:PRK14971 108 ----NLIEQVRIPPQI---------GKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTILSRCQI 174


                 ...
gi 446286710 158 FRF 160
Cdd:PRK14971 175 FDF 177
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
 18-162 8.06e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 56.05  E-value: 8.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSG--NFASLDMALYLAQSQFCEK--------RQSGLPCQECRACRLIANGEFSDVKIIEPQGQlIKTE 87
Cdd:PRK14955  32 LRMGRVGHGYIFSGlrGVGKTTAARVFAKAVNCQRmiddadylQEVTEPCGECESCRDFDAGTSLNISEFDAASN-NSVD 110

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446286710  88 TIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK14955 111 DIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQRFNFKR 185
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
 21-162 1.40e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 55.62  E-value: 1.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  21 DRMSHAYLFSG--NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGefSDVKIIEPQGQLIK-TETIKELTKDFS 97
Cdd:PRK05896  35 NKLTHAYIFSGprGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESINTN--QSVDIVELDAASNNgVDEIRNIIDNIN 112

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446286710  98 RSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK05896 113 YLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTIISRCQRYNFKK 177
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
18-164 3.80e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 54.11  E-value: 3.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGN--FASLDMALYLAQSQFC--EKRQSGL---PCQECRACRLIANGEFSDVkiIEPQGQliKTETIK 90
Cdd:PRK12323  32 LEQQRLHHAYLFTGTrgVGKTTLSRILAKSLNCtgADGEGGItaqPCGQCRACTEIDAGRFVDY--IEMDAA--SNRGVD 107

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446286710  91 ELTKDFSRSGF---EGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFpKQL 164
Cdd:PRK12323 108 EMAQLLDKAVYaptAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNL-KQM 183
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
18-164 4.52e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 54.09  E-value: 4.52e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGN--FASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVkiIEPQGQliKTETIKELTKD 95
Cdd:PRK07003  32 LDGGRLHHAYLFTGTrgVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVDY--VEMDAA--SNRGVDEMAAL 107

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446286710  96 FSRSGF---EGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFpKQL 164
Cdd:PRK07003 108 LERAVYapvDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNL-KQM 178
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
 104-165 1.20e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 51.19  E-value: 1.20e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446286710 104 KSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPKQLD 165
Cdd:PRK08485  54 SEEKIIVIAAPSYGIEAQNALLKILEEPPKNICFIIVAKSKNLLLPTIRSRLIIEKRKQKKP 115
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
 87-162 7.67e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 49.87  E-value: 7.67e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446286710  87 ETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK14970  91 DDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKR 166
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
 78-178 1.16e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 49.02  E-value: 1.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  78 EPQGQLIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQI 157
Cdd:PRK05917  69 QGKGRLHSIETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRSLS 148

                         90       100
                 ....*....|....*....|.
gi 446286710 158 FRFPKQLDMLVHQAEQAGLLK 178
Cdd:PRK05917 149 IHIPMEEKTLVSKEDIAYLIG 169
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
 56-162 1.62e-06

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 49.01  E-value: 1.62e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  56 PCQECRACRLIANGEFSDVKIIEPQGQlIKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSS 135
Cdd:PRK14964  69 PCGTCHNCISIKNSNHPDVIEIDAASN-TSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHV 147

                         90       100
                 ....*....|....*....|....*..
gi 446286710 136 YVILLTNDENNVLPTIKSRTQIFRFPK 162
Cdd:PRK14964 148 KFILATTEVKKIPVTIISRCQRFDLQK 174
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
 84-154 3.01e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 47.53  E-value: 3.01e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446286710  84 IKTETIKELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSR 154
Cdd:PRK06581  69 ISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSR 139
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
 16-158 3.57e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 47.93  E-value: 3.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  16 TILqSDRMSHAYLFSG------NFASLDMALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDVKIIEPQGQlIKTETI 89
Cdd:PRK06645  36 TIL-NDRLAGGYLLTGirgvgkTTSARIIAKAVNCSALITENTTIKTCEQCTNCISFNNHNHPDIIEIDAASK-TSVDDI 113

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446286710  90 KELTKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSRTQIF 158
Cdd:PRK06645 114 RRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIPATIISRCQRY 182
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 18-78 1.73e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 46.01  E-value: 1.73e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446286710  18 LQSDRMSHAYLFSG-------NFASLdmalyLAQSQFCEKRQSGLPCQECRACRLIANGEFSDvkIIE 78
Cdd:PRK07994  32 LDLGRLHHAYLFSGtrgvgktTIARL-----LAKGLNCETGITATPCGECDNCREIEQGRFVD--LIE 92
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 18-154 1.05e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 43.56  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  18 LQSDRMSHAYLFSGNFA----SLdmALYLAQSQFCEKRQSGLPCQECRACRLIANGEFSDvkIIE-PQGQLIKTETIKEL 92
Cdd:PRK14949  32 LTQQRLHHAYLFTGTRGvgktSL--ARLFAKGLNCEQGVTATPCGVCSSCVEIAQGRFVD--LIEvDAASRTKVDDTREL 107

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446286710  93 TKDFSRSGFEGKSQVFIIKDCEKMHVNAANSLLKFIEEPQSSSYVILLTNDENNVLPTIKSR 154
Cdd:PRK14949 108 LDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPVTVLSR 169
44 PHA02544
clamp loader, small subunit; Provisional
 57-167 7.92e-04

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 40.36  E-value: 7.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446286710  57 CQECRACRLIANGefSDVKIiepqgqliktETIKELTKDFSRS-GFEGKSQVFIIKDCEKMHVNAANSLLK-FIEEPQSS 134
Cdd:PHA02544  64 CNEVGAEVLFVNG--SDCRI----------DFVRNRLTRFASTvSLTGGGKVIIIDEFDRLGLADAQRHLRsFMEAYSKN 131

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 446286710 135 SYVILLTNDENNVLPTIKSRTQIFRF--PKQLDML 167
Cdd:PHA02544 132 CSFIITANNKNGIIEPLRSRCRVIDFgvPTKEEQI 166
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH