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Conserved domains on  [gi|446298360|ref|WP_000376215|]
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MULTISPECIES: Lrp/AsnC family transcriptional regulator [Acinetobacter]

Protein Classification

Lrp/AsnC family transcriptional regulator( domain architecture ID 11445815)

Lrp/AsnC (leucine-responsive regulatory protein/asparagine synthase C) family transcriptional regulator regulates many cellular processes such as amino acid metabolism, pili synthesis, and DNA repair and recombination

CATH:  3.30.70.920|1.10.10.10
Gene Ontology:  GO:0043565
PubMed:  16438681|21608015|27206730

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Lrp COG1522
DNA-binding transcriptional regulator, Lrp family [Transcription];
1-139 3.03e-52

DNA-binding transcriptional regulator, Lrp family [Transcription];


:

Pssm-ID: 441131 [Multi-domain]  Cd Length: 138  Bit Score: 162.26  E-value: 3.03e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360   1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLkegDKQAVE 80
Cdd:COG1522    3 LDEIDRRILRLLQEDGRLSFAELAERVGLSESTVLRRVRRLEEAGVIRGYGAVVDPEKLGLGVTAFVEVKV---PPHRLD 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446298360  81 KFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVM 139
Cdd:COG1522   80 EFAEALAAIPEVLECYLVTGDYDLLLKVVARDMEELERFLLERLAALPGVRRTETSFVL 138
 
Name Accession Description Interval E-value
Lrp COG1522
DNA-binding transcriptional regulator, Lrp family [Transcription];
1-139 3.03e-52

DNA-binding transcriptional regulator, Lrp family [Transcription];


Pssm-ID: 441131 [Multi-domain]  Cd Length: 138  Bit Score: 162.26  E-value: 3.03e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360   1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLkegDKQAVE 80
Cdd:COG1522    3 LDEIDRRILRLLQEDGRLSFAELAERVGLSESTVLRRVRRLEEAGVIRGYGAVVDPEKLGLGVTAFVEVKV---PPHRLD 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446298360  81 KFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVM 139
Cdd:COG1522   80 EFAEALAAIPEVLECYLVTGDYDLLLKVVARDMEELERFLLERLAALPGVRRTETSFVL 138
HTH_ASNC smart00344
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase ...
 1-110 1.12e-39

helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli)


Pssm-ID: 214628 [Multi-domain]  Cd Length: 108  Bit Score: 129.17  E-value: 1.12e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360     1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLKEGDKqaVE 80
Cdd:smart00344   1 LDEIDRKILEELQKDARISLAELAKKVGLSPSTVHNRVKRLEEEGVIKGYTAVLNPKKLGLSVTAFVGVTLENPDK--LE 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 446298360    81 KFENAVIEIPQIIQAQRLFGEPDYLLHVVA 110
Cdd:smart00344  79 EFLEKLEKLPEVEEVYLVTGDYDYLLKVRA 108
PRK11169 PRK11169
leucine-responsive transcriptional regulator Lrp;
1-142 5.81e-32

leucine-responsive transcriptional regulator Lrp;


Pssm-ID: 183009 [Multi-domain]  Cd Length: 164  Bit Score: 111.78  E-value: 5.81e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360   1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLKEGDKQAVE 80
Cdd:PRK11169  12 LDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFE 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446298360  81 KFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVMKDV 142
Cdd:PRK11169  92 QFNAAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEV 153
AsnC_trans_reg pfam01037
Lrp/AsnC ligand binding domain; The l-leucine-responsive regulatory protein (Lrp/AsnC) family ...
 67-140 9.47e-19

Lrp/AsnC ligand binding domain; The l-leucine-responsive regulatory protein (Lrp/AsnC) family is a family of similar bacterial transcription regulatory proteins. The family is named after two E. coli proteins involved in regulating amino acid metabolism. This entry corresponds to the usually C-terminal regulatory ligand binding domain. Structurally this domain has a dimeric alpha/beta barrel fold. This domain binds almost exclusively amino acids but also 4-hydroxyphenylpyruvate and kynurenine (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 426007  Cd Length: 73  Bit Score: 74.87  E-value: 9.47e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446298360   67 VFITLKegDKQAVEKFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVMK 140
Cdd:pfam01037   1 VEVKLE--PGHALEEFAEALAAIPEVVECYRVTGDYDYLLKVVARDLEALERFLREKLRSLPGVARTETSIVLS 72
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 2-52 1.11e-07

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 46.52  E-value: 1.11e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446298360   2 DRTDKKILAELqLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRA 52
Cdd:cd00090    6 DPTRLRILRLL-LEGPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRRE 55
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
 2-48 4.63e-03

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 35.79  E-value: 4.63e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 446298360    2 DRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIK 48
Cdd:TIGR01884 142 SREELKILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVE 188
 
Name Accession Description Interval E-value
Lrp COG1522
DNA-binding transcriptional regulator, Lrp family [Transcription];
1-139 3.03e-52

DNA-binding transcriptional regulator, Lrp family [Transcription];


Pssm-ID: 441131 [Multi-domain]  Cd Length: 138  Bit Score: 162.26  E-value: 3.03e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360   1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLkegDKQAVE 80
Cdd:COG1522    3 LDEIDRRILRLLQEDGRLSFAELAERVGLSESTVLRRVRRLEEAGVIRGYGAVVDPEKLGLGVTAFVEVKV---PPHRLD 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446298360  81 KFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVM 139
Cdd:COG1522   80 EFAEALAAIPEVLECYLVTGDYDLLLKVVARDMEELERFLLERLAALPGVRRTETSFVL 138
HTH_ASNC smart00344
helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase ...
 1-110 1.12e-39

helix_turn_helix ASNC type; AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli)


Pssm-ID: 214628 [Multi-domain]  Cd Length: 108  Bit Score: 129.17  E-value: 1.12e-39
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360     1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLKEGDKqaVE 80
Cdd:smart00344   1 LDEIDRKILEELQKDARISLAELAKKVGLSPSTVHNRVKRLEEEGVIKGYTAVLNPKKLGLSVTAFVGVTLENPDK--LE 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 446298360    81 KFENAVIEIPQIIQAQRLFGEPDYLLHVVA 110
Cdd:smart00344  79 EFLEKLEKLPEVEEVYLVTGDYDYLLKVRA 108
PRK11169 PRK11169
leucine-responsive transcriptional regulator Lrp;
1-142 5.81e-32

leucine-responsive transcriptional regulator Lrp;


Pssm-ID: 183009 [Multi-domain]  Cd Length: 164  Bit Score: 111.78  E-value: 5.81e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360   1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLKEGDKQAVE 80
Cdd:PRK11169  12 LDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFE 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446298360  81 KFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVMKDV 142
Cdd:PRK11169  92 QFNAAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEV 153
AsnC_trans_reg pfam01037
Lrp/AsnC ligand binding domain; The l-leucine-responsive regulatory protein (Lrp/AsnC) family ...
 67-140 9.47e-19

Lrp/AsnC ligand binding domain; The l-leucine-responsive regulatory protein (Lrp/AsnC) family is a family of similar bacterial transcription regulatory proteins. The family is named after two E. coli proteins involved in regulating amino acid metabolism. This entry corresponds to the usually C-terminal regulatory ligand binding domain. Structurally this domain has a dimeric alpha/beta barrel fold. This domain binds almost exclusively amino acids but also 4-hydroxyphenylpyruvate and kynurenine (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 426007  Cd Length: 73  Bit Score: 74.87  E-value: 9.47e-19
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446298360   67 VFITLKegDKQAVEKFENAVIEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQRLISTIVMK 140
Cdd:pfam01037   1 VEVKLE--PGHALEEFAEALAAIPEVVECYRVTGDYDYLLKVVARDLEALERFLREKLRSLPGVARTETSIVLS 72
HTH_AsnC-type pfam13404
AsnC-type helix-turn-helix domain;
2-42 2.98e-16

AsnC-type helix-turn-helix domain;


Pssm-ID: 433180 [Multi-domain]  Cd Length: 41  Bit Score: 67.78  E-value: 2.98e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 446298360    2 DRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALE 42
Cdd:pfam13404   1 DEIDRKILRLLQEDARISFAELAERVGLSESTVLRRIRRLE 41
HTH_24 pfam13412
Winged helix-turn-helix DNA-binding;
3-47 6.04e-16

Winged helix-turn-helix DNA-binding;


Pssm-ID: 404317 [Multi-domain]  Cd Length: 45  Bit Score: 67.07  E-value: 6.04e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 446298360    3 RTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAI 47
Cdd:pfam13412   1 ETDRKILNLLQENPRISQRELAERLGLSPSTVNRRLKRLEEEGVI 45
PRK11179 PRK11179
DNA-binding transcriptional regulator AsnC; Provisional
 1-144 2.84e-13

DNA-binding transcriptional regulator AsnC; Provisional


Pssm-ID: 183019 [Multi-domain]  Cd Length: 153  Bit Score: 63.19  E-value: 2.84e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360   1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLKE-GDKQ-A 78
Cdd:PRK11179   7 IDNLDRGILEALMENARTPYAELAKQFGVSPGTIHVRVEKMKQAGIITGTRVDVNPKQLGYDVCCFIGIILKSaKDYPsA 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446298360  79 VEKFEnaviEIPQIIQAQRLFGEPDYLLHVVARDLPAFQRLYDEKLSAIPSVQR---LIS--TIVMKDVVP 144
Cdd:PRK11179  87 LAKLE----SLDEVVEAYYTTGHYSIFIKVMCRSIDALQHVLINKIQTIDEIQStetLISlqNPIMRTIKP 153
HTH_ARSR cd00090
Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric ...
 2-52 1.11e-07

Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.


Pssm-ID: 238042 [Multi-domain]  Cd Length: 78  Bit Score: 46.52  E-value: 1.11e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446298360   2 DRTDKKILAELqLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRA 52
Cdd:cd00090    6 DPTRLRILRLL-LEGPLTVSELAERLGLSQSTVSRHLKKLEEAGLVESRRE 55
COG1777 COG1777
Predicted transcriptional regulator, ArsR family [Transcription];
2-51 4.24e-04

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 441383  Cd Length: 113  Bit Score: 37.71  E-value: 4.24e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 446298360   2 DRTDKKILAELQlNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYR 51
Cdd:COG1777   16 NPTRRRILALLS-EEPAYVSELARELGVSRQAVYKHLRKLEEAGLVESYR 64
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
 1-55 9.00e-04

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 35.64  E-value: 9.00e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446298360    1 MDRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYRAELD 55
Cdd:pfam12802   3 LTPAQFRVLLALARNPGLTVAELARRLGISKQTVSRLVKRLEAKGLVEREPSPAD 57
HTH_20 pfam12840
Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in ...
 2-51 1.28e-03

Helix-turn-helix domain; This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins.


Pssm-ID: 432824 [Multi-domain]  Cd Length: 61  Bit Score: 35.21  E-value: 1.28e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 446298360    2 DRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYR 51
Cdd:pfam12840   9 DPTRLRILRALVGDEPLTASELARRLDISRNTLSYHLRKLEEAGLVEVVR 58
HTH_ICLR smart00346
helix_turn_helix isocitrate lyase regulation;
7-47 1.51e-03

helix_turn_helix isocitrate lyase regulation;


Pssm-ID: 214629 [Multi-domain]  Cd Length: 91  Bit Score: 35.64  E-value: 1.51e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 446298360     7 KILAELQ-LNGRLSITELAEKVGLSISPCHRRVKALEESGAI 47
Cdd:smart00346   9 AVLRALAeEPGGLTLAELAERLGLSKSTAHRLLNTLQELGYV 50
COG4189 COG4189
Predicted transcriptional regulator, ArsR family [Transcription];
7-48 2.46e-03

Predicted transcriptional regulator, ArsR family [Transcription];


Pssm-ID: 443343 [Multi-domain]  Cd Length: 97  Bit Score: 35.32  E-value: 2.46e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 446298360   7 KILAELQLNGrLSITELAEKVGLSISPCHRRVKALEESGAIK 48
Cdd:COG4189   23 RILRLLAEEP-LNVNELAEALGLPKSTVSYHIRKLEEAGLIR 63
COG2512 COG2512
Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain ...
 1-51 3.37e-03

Predicted transcriptional regulator, contains CW (cell wall-binding) repeats and an HTH domain [General function prediction only];


Pssm-ID: 442002 [Multi-domain]  Cd Length: 80  Bit Score: 34.50  E-value: 3.37e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446298360   1 MDRTDKKILAELQLN-GRLSITELAEKVGLSISPCHRRVKALEESGAIKGYR 51
Cdd:COG2512   13 LLEDERRVLELLRENgGRMTQSEIVKETGWSKSKVSRLLSRLEERGLIEKER 64
PriA COG1198
Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, ...
 6-109 4.27e-03

Primosomal protein N' (replication factor Y) - superfamily II helicase [Replication, recombination and repair];


Pssm-ID: 440811 [Multi-domain]  Cd Length: 728  Bit Score: 36.25  E-value: 4.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446298360   6 KKILAELQLNGR-LSITELAEKVGLSISPchrrVKALEESGAIKGYRAELDPNLVGFEFSAIVFITLKEGDKQAVEkfen 84
Cdd:COG1198  134 RRVLEALREHGGpLTLSELAKEAGVSRSV----LKALVKKGLLEIEEREVDRDPFAPDVPAEPPPTLNEEQQAAVE---- 205

                         90       100
                 ....*....|....*....|....*
gi 446298360  85 avieipQIIQAQRLFGEpdYLLHVV 109
Cdd:COG1198  206 ------AIRAAAGGFSV--FLLHGV 222
cas_HTH TIGR01884
CRISPR locus-related DNA-binding protein; Most but not all examples of this family are ...
 2-48 4.63e-03

CRISPR locus-related DNA-binding protein; Most but not all examples of this family are associated with CRISPR loci, a combination of DNA repeats and characteristic proteins encoded near the repeat cluster. The C-terminal region of this protein is homologous to DNA-binding helix-turn-helix domains with predicted transcriptional regulatory activity. [Regulatory functions, DNA interactions, , ]


Pssm-ID: 273852 [Multi-domain]  Cd Length: 203  Bit Score: 35.79  E-value: 4.63e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 446298360    2 DRTDKKILAELQLNGRLSITELAEKVGLSISPCHRRVKALEESGAIK 48
Cdd:TIGR01884 142 SREELKILEVLKATGEKSVKNIAKKLGKSLSTISRHLAELEKKGLVE 188
GlpR COG1349
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ...
 6-48 5.63e-03

DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];


Pssm-ID: 440960 [Multi-domain]  Cd Length: 254  Bit Score: 35.50  E-value: 5.63e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 446298360   6 KKILAELQLNGRLSITELAEKVGLS---IspchRR-VKALEESGAIK 48
Cdd:COG1349    8 QKILELLRERGRVSVEELAERLGVSeetI----RRdLAELEEQGLLR 50
HTH_ARSR smart00418
helix_turn_helix, Arsenical Resistance Operon Repressor;
7-51 6.57e-03

helix_turn_helix, Arsenical Resistance Operon Repressor;


Pssm-ID: 197713 [Multi-domain]  Cd Length: 66  Bit Score: 33.34  E-value: 6.57e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 446298360     7 KILAELqLNGRLSITELAEKVGLSISPCHRRVKALEESGAIKGYR 51
Cdd:smart00418   1 KILKLL-AEGELCVCELAEILGLSQSTVSHHLKKLREAGLVESRR 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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