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Conserved domains on  [gi|446302408|ref|WP_000380263|]
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MULTISPECIES: PTS sugar transporter subunit IIC [Enterobacteriaceae]

Protein Classification

PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC( domain architecture ID 10007905)

PTS mannose/fructose/sorbose/N-acetylgalactosamine-specific transporter subunit IIC is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active transport system that catalyzes the phosphorylation of incoming sugar substrates (such as mannose, fructose, sorbose, and N-acetylgalactosamine) concomitantly with their translocation across the cell membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 3-249 2.71e-79

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


:

Pssm-ID: 442929  Cd Length: 259  Bit Score: 239.25  E-value: 2.71e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408   3 TLLFASLMGLYYWFARLRlGYTFSAMLLQPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTsTPGGNVPSDPALAACIA 82
Cdd:COG3715    4 SLIQAILIGLVAFLAGID-GLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVV-NIGGAVPPDPALAGIIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408  83 IPIAVKANMDPNLAIALAIPFGVIGVFLDQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLvLRFPVVFAANY 162
Cdd:COG3715   82 TALAILSGQDPETAIALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFL-LRAIPVFLALY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408 163 FGQNVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAVLYLKVDIMAMAIFGTCVAFLIKGL 242
Cdd:COG3715  161 FGADAVQALLNAIPAWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLKLPLLAIAIIGVAIALIYYQL 240


                 ....*..
gi 446302408 243 AKNEGAA 249
Cdd:COG3715  241 KKKKNAA 247
 
Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 3-249 2.71e-79

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 442929  Cd Length: 259  Bit Score: 239.25  E-value: 2.71e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408   3 TLLFASLMGLYYWFARLRlGYTFSAMLLQPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTsTPGGNVPSDPALAACIA 82
Cdd:COG3715    4 SLIQAILIGLVAFLAGID-GLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVV-NIGGAVPPDPALAGIIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408  83 IPIAVKANMDPNLAIALAIPFGVIGVFLDQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLvLRFPVVFAANY 162
Cdd:COG3715   82 TALAILSGQDPETAIALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFL-LRAIPVFLALY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408 163 FGQNVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAVLYLKVDIMAMAIFGTCVAFLIKGL 242
Cdd:COG3715  161 FGADAVQALLNAIPAWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLKLPLLAIAIIGVAIALIYYQL 240


                 ....*..
gi 446302408 243 AKNEGAA 249
Cdd:COG3715  241 KKKKNAA 247
EII-Sor pfam03609
PTS system sorbose-specific iic component;
4-238 1.76e-77

PTS system sorbose-specific iic component;


Pssm-ID: 460987  Cd Length: 233  Bit Score: 233.46  E-value: 1.76e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408    4 LLFASLMGLYYWFARLRlGYTFSAMLLQPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTsTPGGNVPSDPALAACIAI 83
Cdd:pfam03609   1 LIQAILIGLVAFLAGLD-GLLGQFTLHRPLVAGTLVGLILGDVQTGLIIGATLQLMYLGVV-TIGGAVPPDAALAGIIGT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408   84 PIAVKANMDPNLAIALAIPFGVIGVFLDQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLVLRFPVVFAANYF 163
Cdd:pfam03609  79 ALAILSGIGPEAAIALAVPVALLGQQLDNLVRTINSFFVHKADKYAEEGNYKGIERIHLLGPQLLGLLIRFIPVFLALYF 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446302408  164 GQNVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAVLYLKVDIMAMAIFGTCVAFL 238
Cdd:pfam03609 159 GADAVQALLNAIPEWLTNGLTVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLKLPLIAIAIIGVAIALI 233
PRK15065 PRK15065
mannose/fructose/sorbose family PTS transporter subunit IIC;
31-249 8.99e-30

mannose/fructose/sorbose family PTS transporter subunit IIC;


Pssm-ID: 237895  Cd Length: 262  Bit Score: 111.86  E-value: 8.99e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408  31 QPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTSTpGGNVPSDPALAACIAIPIAVKANMDPNLAIALAIPFGVIGVFL 110
Cdd:PRK15065  31 RPLVACTLIGLVLGDLKTGIILGGTLEMIALGWMNI-GAAVAPDAALASVISAILVIAGHQGIGTGIAIAIPLAAAGQVL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408 111 DQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLVLRFPVVFAANYFGQNVVESFLKLMPHWLTHSFEIMGGIL 190
Cdd:PRK15065 110 TIIVRTITVAFQHAADKAAEEGNFRAIEWLHVSALLLQALRIAIPAALVALAVGTSAVQSMLNAIPEVLTGGLNIGGGMI 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446302408 191 PALGFAITIMVIGKKSLLPWFIGGFFAVLYLKVDIMAMAIFGTCVAFLIKGLAKNEGAA 249
Cdd:PRK15065 190 VVVGYAMVINMMATRELMPFFYLGFVLAAFTNLNLIALGVIGVVLALIYLQLSPKYGRV 248
 
Name Accession Description Interval E-value
ManY COG3715
Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component ...
 3-249 2.71e-79

Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific IIC component [Carbohydrate transport and metabolism];


Pssm-ID: 442929  Cd Length: 259  Bit Score: 239.25  E-value: 2.71e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408   3 TLLFASLMGLYYWFARLRlGYTFSAMLLQPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTsTPGGNVPSDPALAACIA 82
Cdd:COG3715    4 SLIQAILIGLVAFLAGID-GLLGQFQLHRPLVAGLLVGLILGDVKTGLIIGATLQLIYLGVV-NIGGAVPPDPALAGIIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408  83 IPIAVKANMDPNLAIALAIPFGVIGVFLDQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLvLRFPVVFAANY 162
Cdd:COG3715   82 TALAILSGQDPETAIALAVPVGLLGQVLDILVRTINSFFVHKADKYAEEGNFKGIERLHLLGPLLQFL-LRAIPVFLALY 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408 163 FGQNVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAVLYLKVDIMAMAIFGTCVAFLIKGL 242
Cdd:COG3715  161 FGADAVQALLNAIPAWLTHGLSVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLKLPLLAIAIIGVAIALIYYQL 240


                 ....*..
gi 446302408 243 AKNEGAA 249
Cdd:COG3715  241 KKKKNAA 247
EII-Sor pfam03609
PTS system sorbose-specific iic component;
4-238 1.76e-77

PTS system sorbose-specific iic component;


Pssm-ID: 460987  Cd Length: 233  Bit Score: 233.46  E-value: 1.76e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408    4 LLFASLMGLYYWFARLRlGYTFSAMLLQPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTsTPGGNVPSDPALAACIAI 83
Cdd:pfam03609   1 LIQAILIGLVAFLAGLD-GLLGQFTLHRPLVAGTLVGLILGDVQTGLIIGATLQLMYLGVV-TIGGAVPPDAALAGIIGT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408   84 PIAVKANMDPNLAIALAIPFGVIGVFLDQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLVLRFPVVFAANYF 163
Cdd:pfam03609  79 ALAILSGIGPEAAIALAVPVALLGQQLDNLVRTINSFFVHKADKYAEEGNYKGIERIHLLGPQLLGLLIRFIPVFLALYF 158

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446302408  164 GQNVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAVLYLKVDIMAMAIFGTCVAFL 238
Cdd:pfam03609 159 GADAVQALLNAIPEWLTNGLTVAGGMLPAVGFAMLLKMMGKKKLWPFFFLGFVLAAYLKLPLIAIAIIGVAIALI 233
PRK15065 PRK15065
mannose/fructose/sorbose family PTS transporter subunit IIC;
31-249 8.99e-30

mannose/fructose/sorbose family PTS transporter subunit IIC;


Pssm-ID: 237895  Cd Length: 262  Bit Score: 111.86  E-value: 8.99e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408  31 QPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTSTpGGNVPSDPALAACIAIPIAVKANMDPNLAIALAIPFGVIGVFL 110
Cdd:PRK15065  31 RPLVACTLIGLVLGDLKTGIILGGTLEMIALGWMNI-GAAVAPDAALASVISAILVIAGHQGIGTGIAIAIPLAAAGQVL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408 111 DQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLVLRFPVVFAANYFGQNVVESFLKLMPHWLTHSFEIMGGIL 190
Cdd:PRK15065 110 TIIVRTITVAFQHAADKAAEEGNFRAIEWLHVSALLLQALRIAIPAALVALAVGTSAVQSMLNAIPEVLTGGLNIGGGMI 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446302408 191 PALGFAITIMVIGKKSLLPWFIGGFFAVLYLKVDIMAMAIFGTCVAFLIKGLAKNEGAA 249
Cdd:PRK15065 190 VVVGYAMVINMMATRELMPFFYLGFVLAAFTNLNLIALGVIGVVLALIYLQLSPKYGRV 248
PRK09757 PRK09757
PTS N-acetylgalactosamine transporter subunit IIC;
29-236 4.74e-25

PTS N-acetylgalactosamine transporter subunit IIC;


Pssm-ID: 236621  Cd Length: 267  Bit Score: 99.53  E-value: 4.74e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408  29 LLQPVVVAVFVGLLLGNMPAAMIIGAGMQLVYLGVTSTpGGNVPSDPALAACIAIPIAVKANMDPNLAIALAIPFGVIGV 108
Cdd:PRK09757  30 LFRPIIVCTLTGAILGDIQTGLITGGLTELAFAGLTPA-GGVQPPNPIMAGLMTTVIAWSTGVDAKTAIGLGLPFSLLMQ 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446302408 109 FLDQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLVLRFpVVFAANYFGQNVVESFLKLMPHWLTHSFEIMGG 188
Cdd:PRK09757 109 YVILFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAV-IAFLCTYLAQGAMQALVKAMPAWLTHGFEVAGG 187

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446302408 189 ILPALGFAITIMVIGKKSLLPWFIGGFFAVLYLKV-DIMAMAIFGTCVA 236
Cdd:PRK09757 188 ILPAVGFGLLLRVMFKAQYIPYLIAGFLFVCYIQVsNLLPVAVLGAGFA 236
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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