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Conserved domains on  [gi|446303644|ref|WP_000381499|]
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MULTISPECIES: sigma factor regulator N-terminal domain-containing protein [Bacillus]

Protein Classification

Sigma_reg_N and Sigma_reg_C domain-containing protein( domain architecture ID 10619128)

Sigma_reg_N and Sigma_reg_C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Sigma_reg_N pfam13800
Sigma factor regulator N-terminal; This domain is found near the N-terminus of a sigma factor ...
8-95 4.03e-21

Sigma factor regulator N-terminal; This domain is found near the N-terminus of a sigma factor regulator. The N-terminus is responsible for interaction with the sigma factor.


:

Pssm-ID: 463986  Cd Length: 89  Bit Score: 85.38  E-value: 4.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446303644    8 ALKKAQRKQLLKIIITSILVVIILIPIIYKVGNYFAAKGSMRLHEQLFLYNSIAEPNVQIDSQVTSSSSMFGGNITSNRS 87
Cdd:pfam13800   2 ILKKGKRKSRLRIVLISLIVFLLIFVISIITALYYAPKRGNELREVIELTVEITSPNVYVDSGVTSQSGFFGGEITYDLS 81

                  ....*...
gi 446303644   88 KNINGYVV 95
Cdd:pfam13800  82 KRVGGKEV 89
Sigma_reg_C super family cl16401
Sigma factor regulator C-terminal; This family is the C-terminal domain of a sigma factor ...
166-292 3.00e-17

Sigma factor regulator C-terminal; This family is the C-terminal domain of a sigma factor regulator, this may represent a sensory domain.


The actual alignment was detected with superfamily member pfam13791:

Pssm-ID: 433482  Cd Length: 157  Bit Score: 77.38  E-value: 3.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446303644  166 ENYVAEVAISFDQPYTLKEIQTKI-PDNLNIVWLYM---VSPIRDESGGPAGMPVYGF------------EPGTPLEESY 229
Cdd:pfam13791   6 EGTVAEVYVSFDKAYSYAEVYKMLkPEDLDLLWYAVdtgDEEKLEGDSFISETPPIGFpgnpsssiddfkPKYPDELQNS 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446303644  230 KGFFDSLKQYNDGYDKDIQKFLKSNENKPFDQ---------VKILGVMLTGKTENFKALENQNFIRGASVGV 292
Cdd:pfam13791  86 EEHFIKLLKYLSDQEDIAKMLNADLLDGKLDErykyvkkngVKIYGVVVTGPTKELLKLEKEPEVKAAYVGE 157
 
Name Accession Description Interval E-value
Sigma_reg_N pfam13800
Sigma factor regulator N-terminal; This domain is found near the N-terminus of a sigma factor ...
8-95 4.03e-21

Sigma factor regulator N-terminal; This domain is found near the N-terminus of a sigma factor regulator. The N-terminus is responsible for interaction with the sigma factor.


Pssm-ID: 463986  Cd Length: 89  Bit Score: 85.38  E-value: 4.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446303644    8 ALKKAQRKQLLKIIITSILVVIILIPIIYKVGNYFAAKGSMRLHEQLFLYNSIAEPNVQIDSQVTSSSSMFGGNITSNRS 87
Cdd:pfam13800   2 ILKKGKRKSRLRIVLISLIVFLLIFVISIITALYYAPKRGNELREVIELTVEITSPNVYVDSGVTSQSGFFGGEITYDLS 81

                  ....*...
gi 446303644   88 KNINGYVV 95
Cdd:pfam13800  82 KRVGGKEV 89
Sigma_reg_C pfam13791
Sigma factor regulator C-terminal; This family is the C-terminal domain of a sigma factor ...
166-292 3.00e-17

Sigma factor regulator C-terminal; This family is the C-terminal domain of a sigma factor regulator, this may represent a sensory domain.


Pssm-ID: 433482  Cd Length: 157  Bit Score: 77.38  E-value: 3.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446303644  166 ENYVAEVAISFDQPYTLKEIQTKI-PDNLNIVWLYM---VSPIRDESGGPAGMPVYGF------------EPGTPLEESY 229
Cdd:pfam13791   6 EGTVAEVYVSFDKAYSYAEVYKMLkPEDLDLLWYAVdtgDEEKLEGDSFISETPPIGFpgnpsssiddfkPKYPDELQNS 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446303644  230 KGFFDSLKQYNDGYDKDIQKFLKSNENKPFDQ---------VKILGVMLTGKTENFKALENQNFIRGASVGV 292
Cdd:pfam13791  86 EEHFIKLLKYLSDQEDIAKMLNADLLDGKLDErykyvkkngVKIYGVVVTGPTKELLKLEKEPEVKAAYVGE 157
 
Name Accession Description Interval E-value
Sigma_reg_N pfam13800
Sigma factor regulator N-terminal; This domain is found near the N-terminus of a sigma factor ...
8-95 4.03e-21

Sigma factor regulator N-terminal; This domain is found near the N-terminus of a sigma factor regulator. The N-terminus is responsible for interaction with the sigma factor.


Pssm-ID: 463986  Cd Length: 89  Bit Score: 85.38  E-value: 4.03e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446303644    8 ALKKAQRKQLLKIIITSILVVIILIPIIYKVGNYFAAKGSMRLHEQLFLYNSIAEPNVQIDSQVTSSSSMFGGNITSNRS 87
Cdd:pfam13800   2 ILKKGKRKSRLRIVLISLIVFLLIFVISIITALYYAPKRGNELREVIELTVEITSPNVYVDSGVTSQSGFFGGEITYDLS 81

                  ....*...
gi 446303644   88 KNINGYVV 95
Cdd:pfam13800  82 KRVGGKEV 89
Sigma_reg_C pfam13791
Sigma factor regulator C-terminal; This family is the C-terminal domain of a sigma factor ...
166-292 3.00e-17

Sigma factor regulator C-terminal; This family is the C-terminal domain of a sigma factor regulator, this may represent a sensory domain.


Pssm-ID: 433482  Cd Length: 157  Bit Score: 77.38  E-value: 3.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446303644  166 ENYVAEVAISFDQPYTLKEIQTKI-PDNLNIVWLYM---VSPIRDESGGPAGMPVYGF------------EPGTPLEESY 229
Cdd:pfam13791   6 EGTVAEVYVSFDKAYSYAEVYKMLkPEDLDLLWYAVdtgDEEKLEGDSFISETPPIGFpgnpsssiddfkPKYPDELQNS 85
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446303644  230 KGFFDSLKQYNDGYDKDIQKFLKSNENKPFDQ---------VKILGVMLTGKTENFKALENQNFIRGASVGV 292
Cdd:pfam13791  86 EEHFIKLLKYLSDQEDIAKMLNADLLDGKLDErykyvkkngVKIYGVVVTGPTKELLKLEKEPEVKAAYVGE 157
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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