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MULTISPECIES: xanthine dehydrogenase molybdenum-binding subunit XdhA [Enterobacteriaceae]
Protein Classification
xanthine dehydrogenase molybdenum-binding subunit XdhA ( domain architecture ID 11484539 )
xanthine dehydrogenase molybdenum-binding subunit XdhA participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism)
List of domain hits
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
7-765
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1443.73
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 7 T A T G E S C MRVDAIAKVTGRA R YTDDYVMAGM C YAKYVRSPIAHG YAV SI ND E Q ARSLPGV L A I FTWEDVPDIPF A TAGH A 86
Cdd:PRK09970 1 M A I G K S I MRVDAIAKVTGRA K YTDDYVMAGM L YAKYVRSPIAHG KVK SI DT E E ARSLPGV E A V FTWEDVPDIPF P TAGH P 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 87 W T LD E N K RD T ADRALLTRHVRHHGDAVA I VVARDELTAEKA AQ L VSI E WQ ELPVIT T PEAALAE D A A PIHNG - GNLLKQS 165
Cdd:PRK09970 81 W S LD P N H RD I ADRALLTRHVRHHGDAVA A VVARDELTAEKA LK L IKV E YE ELPVIT D PEAALAE G A P PIHNG r GNLLKQS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 166 TMSTGNVQQTI D AADYQVQGHY Q TP VI QHCHME S VTS L A W MEDD S RITIVSSTQIPHIVRRVVGQAL D IPW SC VRVIKP F 245
Cdd:PRK09970 161 TMSTGNVQQTI K AADYQVQGHY E TP IV QHCHME N VTS Y A Y MEDD G RITIVSSTQIPHIVRRVVGQAL G IPW GK VRVIKP Y 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 246 VGGGFGNKQDVLEEP M AAFLTSK L GG I PVKVSLSREECFLATRTRHAFTID GQ MGVNRDGTLKGYSLDVLSNTGAYASHG 325
Cdd:PRK09970 241 VGGGFGNKQDVLEEP L AAFLTSK V GG R PVKVSLSREECFLATRTRHAFTID IK MGVNRDGTLKGYSLDVLSNTGAYASHG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 326 HSIASAGGNKVAYLYPRCAY A YSSKT C YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE I RLRNAAREGDANP 405
Cdd:PRK09970 321 HSIASAGGNKVAYLYPRCAY K YSSKT V YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE F RLRNAAREGDANP 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 406 L T GKRIYSAGLPECLEKGRKIFEW E KRRAEC Q NQQGNLRRGVGVACFSYTS N TWPVG V EIAGARLLMNQDGT IN VQSGAT 485
Cdd:PRK09970 401 L S GKRIYSAGLPECLEKGRKIFEW D KRRAEC K NQQGNLRRGVGVACFSYTS G TWPVG L EIAGARLLMNQDGT VQ VQSGAT 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 486 EIGQG A DTVFSQMVAETVG V PVSDVRVISTQDTDVTPFDPGA F ASRQSYVA A PA L R S AAL L LKEKI I AHAAVMLHQSAMN 565
Cdd:PRK09970 481 EIGQG S DTVFSQMVAETVG I PVSDVRVISTQDTDVTPFDPGA Y ASRQSYVA G PA I R K AAL E LKEKI L AHAAVMLHQSAMN 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 566 L TL I K GHIV l V E RP E EPLMSL KD LAMDA F YHPERGGQ LS AESSIKTTTNPPAFGCTFVD LT VDIALCKVTINRILNVHDS 645
Cdd:PRK09970 561 L DI I D GHIV - V K RP G EPLMSL EE LAMDA Y YHPERGGQ IT AESSIKTTTNPPAFGCTFVD VE VDIALCKVTINRILNVHDS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 646 GHILNPLLAEGQVHGGMGMGIGWALFEEMIID A K S GVVRNPNLLDYK M PTM P DLPQLESAFVEI N EPQSAYGHKSLGEPP 725
Cdd:PRK09970 640 GHILNPLLAEGQVHGGMGMGIGWALFEEMIID E K T GVVRNPNLLDYK L PTM M DLPQLESAFVEI Y EPQSAYGHKSLGEPP 719
730 740 750 760
....*....|....*....|....*....|....*....|
gi 446310295 726 II PV A A AIRNAV K MATGVAINTLP L TP K RL Y EEF HL AGLI 765
Cdd:PRK09970 720 II SP A P AIRNAV L MATGVAINTLP M TP Q RL F EEF KE AGLI 759
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
7-765
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1443.73
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 7 T A T G E S C MRVDAIAKVTGRA R YTDDYVMAGM C YAKYVRSPIAHG YAV SI ND E Q ARSLPGV L A I FTWEDVPDIPF A TAGH A 86
Cdd:PRK09970 1 M A I G K S I MRVDAIAKVTGRA K YTDDYVMAGM L YAKYVRSPIAHG KVK SI DT E E ARSLPGV E A V FTWEDVPDIPF P TAGH P 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 87 W T LD E N K RD T ADRALLTRHVRHHGDAVA I VVARDELTAEKA AQ L VSI E WQ ELPVIT T PEAALAE D A A PIHNG - GNLLKQS 165
Cdd:PRK09970 81 W S LD P N H RD I ADRALLTRHVRHHGDAVA A VVARDELTAEKA LK L IKV E YE ELPVIT D PEAALAE G A P PIHNG r GNLLKQS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 166 TMSTGNVQQTI D AADYQVQGHY Q TP VI QHCHME S VTS L A W MEDD S RITIVSSTQIPHIVRRVVGQAL D IPW SC VRVIKP F 245
Cdd:PRK09970 161 TMSTGNVQQTI K AADYQVQGHY E TP IV QHCHME N VTS Y A Y MEDD G RITIVSSTQIPHIVRRVVGQAL G IPW GK VRVIKP Y 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 246 VGGGFGNKQDVLEEP M AAFLTSK L GG I PVKVSLSREECFLATRTRHAFTID GQ MGVNRDGTLKGYSLDVLSNTGAYASHG 325
Cdd:PRK09970 241 VGGGFGNKQDVLEEP L AAFLTSK V GG R PVKVSLSREECFLATRTRHAFTID IK MGVNRDGTLKGYSLDVLSNTGAYASHG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 326 HSIASAGGNKVAYLYPRCAY A YSSKT C YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE I RLRNAAREGDANP 405
Cdd:PRK09970 321 HSIASAGGNKVAYLYPRCAY K YSSKT V YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE F RLRNAAREGDANP 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 406 L T GKRIYSAGLPECLEKGRKIFEW E KRRAEC Q NQQGNLRRGVGVACFSYTS N TWPVG V EIAGARLLMNQDGT IN VQSGAT 485
Cdd:PRK09970 401 L S GKRIYSAGLPECLEKGRKIFEW D KRRAEC K NQQGNLRRGVGVACFSYTS G TWPVG L EIAGARLLMNQDGT VQ VQSGAT 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 486 EIGQG A DTVFSQMVAETVG V PVSDVRVISTQDTDVTPFDPGA F ASRQSYVA A PA L R S AAL L LKEKI I AHAAVMLHQSAMN 565
Cdd:PRK09970 481 EIGQG S DTVFSQMVAETVG I PVSDVRVISTQDTDVTPFDPGA Y ASRQSYVA G PA I R K AAL E LKEKI L AHAAVMLHQSAMN 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 566 L TL I K GHIV l V E RP E EPLMSL KD LAMDA F YHPERGGQ LS AESSIKTTTNPPAFGCTFVD LT VDIALCKVTINRILNVHDS 645
Cdd:PRK09970 561 L DI I D GHIV - V K RP G EPLMSL EE LAMDA Y YHPERGGQ IT AESSIKTTTNPPAFGCTFVD VE VDIALCKVTINRILNVHDS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 646 GHILNPLLAEGQVHGGMGMGIGWALFEEMIID A K S GVVRNPNLLDYK M PTM P DLPQLESAFVEI N EPQSAYGHKSLGEPP 725
Cdd:PRK09970 640 GHILNPLLAEGQVHGGMGMGIGWALFEEMIID E K T GVVRNPNLLDYK L PTM M DLPQLESAFVEI Y EPQSAYGHKSLGEPP 719
730 740 750 760
....*....|....*....|....*....|....*....|
gi 446310295 726 II PV A A AIRNAV K MATGVAINTLP L TP K RL Y EEF HL AGLI 765
Cdd:PRK09970 720 II SP A P AIRNAV L MATGVAINTLP M TP Q RL F EEF KE AGLI 759
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
2-760
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 822.56
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 2 EAREATAT G ESCM RVD AI AKVTGRARYTDD YVMA GM C YA KY VRSP I AH GYAV SI NDEQ A RS LPGV L A IF T W ED V P DIP F A 81
Cdd:COG1529 3 DPADFRII G KPVP RVD GP AKVTGRARYTDD IRLP GM L YA AV VRSP H AH ARIK SI DTSA A LA LPGV V A VL T G ED L P GLK F G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 82 TA G HAWT ldenkrdta DRA L LTRH VR HH G DA VA I VVA RDELT A EK AA Q L VSI E WQE LP VITT PEAALA ED A API H -- NG G 159
Cdd:COG1529 83 LP G PDPD --------- QPP L ADDK VR YV G EP VA A VVA ETREA A RD AA E L IKV E YEP LP AVVD PEAALA PG A PLV H ee LP G 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 160 N LLKQSTMST G N V QQTIDA AD YQ V QGH Y Q TP VIQ H CH ME SVTSL A WMED D S R I T IVS STQ I PH I VRR VVGQ AL DI P WSC V 239
Cdd:COG1529 154 N VAAEWRGER G D V DAAFAE AD VV V EAT Y T TP RLA H AP ME PRAAV A EWDG D G R L T VWA STQ G PH L VRR ALAR AL GL P PEK V 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 240 RVI K P F VGGGFG N K Q DV - L EE PM AA FLTS KLG G i PVK VS L S REE C FLA TRT RHA FTIDGQM G VNR DG TLKGYSL DV LSN T 318
Cdd:COG1529 234 RVI A P D VGGGFG G K L DV y P EE VL AA LAAR KLG R - PVK LV L T REE D FLA DTH RHA TVQRVRL G ADK DG KITALRH DV VAD T 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 319 GAYAS H G HSIASA G GNKVAYL Y PRCAYAYSSKTC YTN L P SA GA M RG Y G A PQ VV FA V ES ML D DA A TA LG I DPVE I RLRN AA 398
Cdd:COG1529 313 GAYAS F G EAVLPL G ATMATGP Y AIPNVRVEARAV YTN T P PT GA Y RG P G R PQ AA FA L ES AM D EL A EE LG M DPVE L RLRN LI 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 399 R E GD AN P l TG KRIY S AG L P ECLEK GRKI F E W EK RRA ECQNQQGNLR RG V GVA CFSYT S N twp V G VEIAG AR LLM N Q DG TI 478
Cdd:COG1529 393 R P GD FP P - TG QPYD S GR L A ECLEK AAEA F G W GE RRA RPAEARAGKL RG I GVA AYIEG S G --- G G GDPES AR VRL N P DG SV 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 479 N V QS GAT E IGQG AD TV FS Q MV AE TV GVP VS DVRV I s TQ DTD V TP FDP G AFA SR QSY V AAP A L R S AA LL L K EK IIAH AA VM 558
Cdd:COG1529 469 T V YT GAT D IGQG HE TV LA Q IA AE EL GVP PE DVRV V - LG DTD L TP YGG G TGG SR STA V GGS A V R K AA EK L R EK LLEL AA HL 547
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 559 L HQSAMN L TLIK G HIVLVE R P eepl M SL KD LA MD A F Y hperg G Q L S A ESSIKTT T N P - PA FG CTFVDLT VD IALCK V TIN 637
Cdd:COG1529 548 L GADPED L EFED G RVRVPG R S ---- V SL AE LA AA A Y Y ----- G G L E A TGTYDPP T Y P t YS FG AHVAEVE VD PETGE V RVL 618
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 638 R ILN VHD S G HIL NPLL A EGQV H GG MGM GIG W AL F EE MII D a KS G VVR N P N LL DY KM P TMP D L P QL E SA FVE INE P QSAY G 717
Cdd:COG1529 619 R VVA VHD C G RVI NPLL V EGQV E GG VVQ GIG Q AL Y EE LVY D - ED G QLL N A N FA DY LV P RAA D V P EI E VI FVE TPD P TNPL G 697
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 446310295 718 H K SL GEP PI I P VA A AI R NAV KM ATGV A I NT LP L TP KRLYEEFH 760
Cdd:COG1529 698 A K GV GEP GT I G VA P AI A NAV YD ATGV R I RD LP I TP EKVLAALR 740
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
422-700
9.29e-93
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 290.98
E-value: 9.29e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 422 K GRKIFEWEK RRAE CQNQ - Q GN LR RG V G V A CFSYT S NTW P VGVEI AGA RLLM N Q DG TIN V QS G A TE I GQG AD T VFS Q MV A 500
Cdd:pfam20256 1 K ALELSDYDE RRAE QAEF n R GN RK RG I G I A PYVEG S GLG P GALNQ AGA LVRL N P DG SVT V YT G G TE M GQG LE T KLA Q IA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 501 E TV G V P VS DVRV IST q DTD VT P FDP G AF ASR QSY V AAP A LRS AA LL L K E KIIAH AA VM L HQ S AMN L TLIK G HIVLVER P E 580
Cdd:pfam20256 81 E AL G I P PE DVRV VEG - DTD TV P NGG G TG ASR STD V GGN A VLL AA EK L R E RLLKI AA HL L EA S PED L EFED G KVYVKGD P R 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 581 E pl MSLKD LA MD A F yhp ER G GQ LSA ESS ----- IK T TTN PP ---- AF G CTFVDLT VD IALCK V TIN R ILN VHD S G HIL NP 651
Cdd:pfam20256 160 S -- VTFAE LA AA A Y --- GE G VG LSA TGF ytppd DE T GQG PP fayy PY G AHAAEVE VD PETGE V RVL R YVA VHD C G RVI NP 234
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 446310295 652 LLA EGQ VH GG MGM GIG W AL F EE MII D a KS G VVRNPN L L DYK M PT MP D L P 700
Cdd:pfam20256 235 AIV EGQ IE GG FVQ GIG L AL M EE LVY D - ED G QLLTAS L M DYK I PT AA D I P 282
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
10-755
3.90e-56
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 209.10
E-value: 3.90e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 10 G ESC M RVDAIAKV TG R A R Y T DD YVMAGM - CYAKY V R S PI AH GYA VSI NDEQ A R SLPGV LA I F T W E DVP D I pf A T A G hawt 88
Cdd:TIGR02969 577 G HPI M HLSGVKHA TG E A I Y C DD MPAVDQ e LFLTF V T S SR AH AKI VSI DLSE A L SLPGV VD I I T A E HLQ D A -- N T F G ---- 650
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 89 ldenkrdt ADRA L L T RH V RHH G DA V AI V V A RD E LT A EK AA QL V S I EWQE L - P V I T T P E A A laedaap I HNGGNLLKQSTM 167
Cdd:TIGR02969 651 -------- TEKL L A T DK V HCV G QL V CA V I A DS E VQ A KQ AA KH V K I VYRD L e P L I L T I E E A ------- I QHKSFFEPERKL 715
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 168 ST GNV QQTIDAA D YQVQ G HYQTPVIQ H CH ME SVTS L AWME - D D SRITIVS STQ I P HIVRRV V GQA L DI P WSC V RVIKPF V 246
Cdd:TIGR02969 716 EY GNV DEAFKVV D QILE G EIHMGGQE H FY ME TQSM L VVPK g E D QEMDVYV STQ F P KYIQDI V AAT L KL P VNK V MCHVRR V 795
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 247 GG G FG N K -- QDVLEEPMA AF LTS K l G G IP V KVS L S R E E CF L A T RT RH AFTIDGQM G VNR DG TLKGYSLDVL SN T G AYASH 324
Cdd:TIGR02969 796 GG A FG G K vg KTSIMAAIT AF AAN K - H G RA V RCT L E R G E DM L I T GG RH PYLGKYKA G FMN DG RIVALDVEHY SN G G SSLDE 874
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 325 GHSIASA G GN K V -- AY LY P -- RC ayay SSKT C Y TNLPS AG A M RG Y G A PQ VVFAV E SMLDDA A TAL G ID P VEI R LR N AAR E 400
Cdd:TIGR02969 875 SLWVIEM G LL K M dn AY KF P nl RC ---- RGWA C R TNLPS NT A F RG F G F PQ AGLIT E ACITEV A AKC G LS P EKV R TI N MYK E 950
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 401 G D AN P LT g KR I YSAG L PE C LEKGRKIFEWEK R RAECQ -- N QQGNLR - RG VG V ACFSYTSNTWP V GVEI A G A RLLMNQ DG T 477
Cdd:TIGR02969 951 I D QT P YK - QE I NAKN L FQ C WRECMAKSSYSE R KVAVE kf N AENYWK k RG LA V IPLKFPVGLGS V AMGQ A A A LVHIYL DG S 1029
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 478 IN V QS G AT E I GQG AD T VFS Q M V AETVGV P V S D V RVIS T QDTD V tpfd P GAF AS RQ S Y VA --- AP A LRS A A - L LLK -- E K I 551
Cdd:TIGR02969 1030 VL V TH G GI E M GQG VH T KMI Q V V SRELKM P M S N V HLRG T STET V ---- P NTN AS GG S V VA dln GL A VKD A C q T LLK rl E P I 1105
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 552 I A haavmlhqsamnltlikghivlverp EE P LMSL KD L A MD AF yhp ERGGQ LSA ------- ES S I --- K TTTN P PAF --- 618
Cdd:TIGR02969 1106 I S -------------------------- KN P QGTW KD W A QT AF --- DQSIS LSA vgyfrgy ES N I nwe K GEGH P FEY fvy 1156
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 619 -- G C TF V D --- LT V D IALCKVT I nriln V H D S GH IL NP L L AE GQV H G GMGM G I G WALF EE MIIDAK s G VV -- R N PN ll D Y 691
Cdd:TIGR02969 1157 ga A C SE V E idc LT G D HKNIRTD I ----- V M D V GH SI NP A L DI GQV E G AFIQ G M G LYTI EE LSYSPQ - G IL ys R G PN -- Q Y 1228
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446310295 692 K M P TMP D L P - Q L ESA F VEIN E - PQSA Y GH K S LGE PPII --- P V AA AI RN AV KM A ------ T G VAIN T L PLTP KRL 755
Cdd:TIGR02969 1229 K I P AIC D I P t E L HIS F LPPS E h SNTL Y SS K G LGE SGVF lgc S V FF AI HD AV RA A rqergl S G PWKL T S PLTP EKI 1303
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
23-139
2.77e-37
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 134.95
E-value: 2.77e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 23 TG R ARY T DD YVMA GM CY A KY VRSP I AH GYAV SI NDEQ AR SL PGV L A IF T WE DVP DIPFATAGH awtldenkrd TADRA L L 102
Cdd:smart01008 1 TG E ARY G DD IRLP GM LH A AV VRSP V AH ARIK SI DTSA AR AM PGV V A VL T AK DVP GLNDFGPLG ---------- PDEPV L A 70
90 100 110
....*....|....*....|....*....|....*..
gi 446310295 103 TRH VR HH G DA VA I VVA RD E LT A EK AA QL V SI E WQ ELP 139
Cdd:smart01008 71 DDK VR YV G QP VA A VVA ET E EA A RD AA EA V KV E YE ELP 107
Name
Accession
Description
Interval
E-value
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
7-765
0e+00
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 1443.73
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 7 T A T G E S C MRVDAIAKVTGRA R YTDDYVMAGM C YAKYVRSPIAHG YAV SI ND E Q ARSLPGV L A I FTWEDVPDIPF A TAGH A 86
Cdd:PRK09970 1 M A I G K S I MRVDAIAKVTGRA K YTDDYVMAGM L YAKYVRSPIAHG KVK SI DT E E ARSLPGV E A V FTWEDVPDIPF P TAGH P 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 87 W T LD E N K RD T ADRALLTRHVRHHGDAVA I VVARDELTAEKA AQ L VSI E WQ ELPVIT T PEAALAE D A A PIHNG - GNLLKQS 165
Cdd:PRK09970 81 W S LD P N H RD I ADRALLTRHVRHHGDAVA A VVARDELTAEKA LK L IKV E YE ELPVIT D PEAALAE G A P PIHNG r GNLLKQS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 166 TMSTGNVQQTI D AADYQVQGHY Q TP VI QHCHME S VTS L A W MEDD S RITIVSSTQIPHIVRRVVGQAL D IPW SC VRVIKP F 245
Cdd:PRK09970 161 TMSTGNVQQTI K AADYQVQGHY E TP IV QHCHME N VTS Y A Y MEDD G RITIVSSTQIPHIVRRVVGQAL G IPW GK VRVIKP Y 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 246 VGGGFGNKQDVLEEP M AAFLTSK L GG I PVKVSLSREECFLATRTRHAFTID GQ MGVNRDGTLKGYSLDVLSNTGAYASHG 325
Cdd:PRK09970 241 VGGGFGNKQDVLEEP L AAFLTSK V GG R PVKVSLSREECFLATRTRHAFTID IK MGVNRDGTLKGYSLDVLSNTGAYASHG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 326 HSIASAGGNKVAYLYPRCAY A YSSKT C YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE I RLRNAAREGDANP 405
Cdd:PRK09970 321 HSIASAGGNKVAYLYPRCAY K YSSKT V YTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVE F RLRNAAREGDANP 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 406 L T GKRIYSAGLPECLEKGRKIFEW E KRRAEC Q NQQGNLRRGVGVACFSYTS N TWPVG V EIAGARLLMNQDGT IN VQSGAT 485
Cdd:PRK09970 401 L S GKRIYSAGLPECLEKGRKIFEW D KRRAEC K NQQGNLRRGVGVACFSYTS G TWPVG L EIAGARLLMNQDGT VQ VQSGAT 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 486 EIGQG A DTVFSQMVAETVG V PVSDVRVISTQDTDVTPFDPGA F ASRQSYVA A PA L R S AAL L LKEKI I AHAAVMLHQSAMN 565
Cdd:PRK09970 481 EIGQG S DTVFSQMVAETVG I PVSDVRVISTQDTDVTPFDPGA Y ASRQSYVA G PA I R K AAL E LKEKI L AHAAVMLHQSAMN 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 566 L TL I K GHIV l V E RP E EPLMSL KD LAMDA F YHPERGGQ LS AESSIKTTTNPPAFGCTFVD LT VDIALCKVTINRILNVHDS 645
Cdd:PRK09970 561 L DI I D GHIV - V K RP G EPLMSL EE LAMDA Y YHPERGGQ IT AESSIKTTTNPPAFGCTFVD VE VDIALCKVTINRILNVHDS 639
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 646 GHILNPLLAEGQVHGGMGMGIGWALFEEMIID A K S GVVRNPNLLDYK M PTM P DLPQLESAFVEI N EPQSAYGHKSLGEPP 725
Cdd:PRK09970 640 GHILNPLLAEGQVHGGMGMGIGWALFEEMIID E K T GVVRNPNLLDYK L PTM M DLPQLESAFVEI Y EPQSAYGHKSLGEPP 719
730 740 750 760
....*....|....*....|....*....|....*....|
gi 446310295 726 II PV A A AIRNAV K MATGVAINTLP L TP K RL Y EEF HL AGLI 765
Cdd:PRK09970 720 II SP A P AIRNAV L MATGVAINTLP M TP Q RL F EEF KE AGLI 759
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
2-760
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 822.56
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 2 EAREATAT G ESCM RVD AI AKVTGRARYTDD YVMA GM C YA KY VRSP I AH GYAV SI NDEQ A RS LPGV L A IF T W ED V P DIP F A 81
Cdd:COG1529 3 DPADFRII G KPVP RVD GP AKVTGRARYTDD IRLP GM L YA AV VRSP H AH ARIK SI DTSA A LA LPGV V A VL T G ED L P GLK F G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 82 TA G HAWT ldenkrdta DRA L LTRH VR HH G DA VA I VVA RDELT A EK AA Q L VSI E WQE LP VITT PEAALA ED A API H -- NG G 159
Cdd:COG1529 83 LP G PDPD --------- QPP L ADDK VR YV G EP VA A VVA ETREA A RD AA E L IKV E YEP LP AVVD PEAALA PG A PLV H ee LP G 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 160 N LLKQSTMST G N V QQTIDA AD YQ V QGH Y Q TP VIQ H CH ME SVTSL A WMED D S R I T IVS STQ I PH I VRR VVGQ AL DI P WSC V 239
Cdd:COG1529 154 N VAAEWRGER G D V DAAFAE AD VV V EAT Y T TP RLA H AP ME PRAAV A EWDG D G R L T VWA STQ G PH L VRR ALAR AL GL P PEK V 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 240 RVI K P F VGGGFG N K Q DV - L EE PM AA FLTS KLG G i PVK VS L S REE C FLA TRT RHA FTIDGQM G VNR DG TLKGYSL DV LSN T 318
Cdd:COG1529 234 RVI A P D VGGGFG G K L DV y P EE VL AA LAAR KLG R - PVK LV L T REE D FLA DTH RHA TVQRVRL G ADK DG KITALRH DV VAD T 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 319 GAYAS H G HSIASA G GNKVAYL Y PRCAYAYSSKTC YTN L P SA GA M RG Y G A PQ VV FA V ES ML D DA A TA LG I DPVE I RLRN AA 398
Cdd:COG1529 313 GAYAS F G EAVLPL G ATMATGP Y AIPNVRVEARAV YTN T P PT GA Y RG P G R PQ AA FA L ES AM D EL A EE LG M DPVE L RLRN LI 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 399 R E GD AN P l TG KRIY S AG L P ECLEK GRKI F E W EK RRA ECQNQQGNLR RG V GVA CFSYT S N twp V G VEIAG AR LLM N Q DG TI 478
Cdd:COG1529 393 R P GD FP P - TG QPYD S GR L A ECLEK AAEA F G W GE RRA RPAEARAGKL RG I GVA AYIEG S G --- G G GDPES AR VRL N P DG SV 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 479 N V QS GAT E IGQG AD TV FS Q MV AE TV GVP VS DVRV I s TQ DTD V TP FDP G AFA SR QSY V AAP A L R S AA LL L K EK IIAH AA VM 558
Cdd:COG1529 469 T V YT GAT D IGQG HE TV LA Q IA AE EL GVP PE DVRV V - LG DTD L TP YGG G TGG SR STA V GGS A V R K AA EK L R EK LLEL AA HL 547
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 559 L HQSAMN L TLIK G HIVLVE R P eepl M SL KD LA MD A F Y hperg G Q L S A ESSIKTT T N P - PA FG CTFVDLT VD IALCK V TIN 637
Cdd:COG1529 548 L GADPED L EFED G RVRVPG R S ---- V SL AE LA AA A Y Y ----- G G L E A TGTYDPP T Y P t YS FG AHVAEVE VD PETGE V RVL 618
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 638 R ILN VHD S G HIL NPLL A EGQV H GG MGM GIG W AL F EE MII D a KS G VVR N P N LL DY KM P TMP D L P QL E SA FVE INE P QSAY G 717
Cdd:COG1529 619 R VVA VHD C G RVI NPLL V EGQV E GG VVQ GIG Q AL Y EE LVY D - ED G QLL N A N FA DY LV P RAA D V P EI E VI FVE TPD P TNPL G 697
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 446310295 718 H K SL GEP PI I P VA A AI R NAV KM ATGV A I NT LP L TP KRLYEEFH 760
Cdd:COG1529 698 A K GV GEP GT I G VA P AI A NAV YD ATGV R I RD LP I TP EKVLAALR 740
PRK09800
PRK09800 putative hypoxanthine oxidase; Provisional
10-755
9.04e-130
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain]
Cd Length: 956
Bit Score: 409.61
E-value: 9.04e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 10 G ESCMRV DA IAK V TGRAR Y TD D Y V M A GM C YA K YV RSP I AH GYAVSINDEQ A RS LPGV LAIF T WEDV PDI PFATA G HAWT l 89
Cdd:PRK09800 173 G KHYPKT DA AKM V QAKPC Y VE D R V T A DA C VI K ML RSP H AH ALITHLDVSK A EA LPGV VHVI T HLNC PDI YYTPG G QSAP - 251
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 90 den KRDTA DR ALLTRHV RH H GD A VA I VVA RD E LT A EK A AQ L VSI E WQE L PVITTPEA A L AEDA API H NG ----------- 158
Cdd:PRK09800 252 --- EPSPL DR RMFGKKM RH V GD R VA A VVA ES E EI A LE A LK L IDV E YEV L KPVMSIDE A M AEDA PVV H DE pvvyvagapdt 328
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 159 -------------------------- G N LLKQSTMST G NVQQTIDA AD YQVQGH Y QTPVI Q H C HM E SVTSLAW M e D DS R I 212
Cdd:PRK09800 329 leddnshaaqrgehmiinfpigsrpr K N IAASIHGHI G DMDKGFAD AD VIIERT Y NSTQA Q Q C PT E THICFTR M - D GD R L 407
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 213 T I VS STQ I P HIV RR V V GQALDIPWSC V R VIK PF VGGGFG N KQD V L E E PMA A FL T s KLG G I PV KVSLS REE C F L A TRT RH A 292
Cdd:PRK09800 408 V I HA STQ V P WHL RR Q V ARLVGMKQHK V H VIK ER VGGGFG S KQD I L L E EVC A WA T - CVT G R PV LFRYT REE E F I A NTS RH V 486
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 293 FTIDGQM G VNR DG T L KGYSL D VLS NTG A Y AS H GHSIASA G GNKVAY LYP RCAYAYSSK T C Y T N LPSA GA MR GYGAP QVV F 372
Cdd:PRK09800 487 AKVTVKL G AKK DG R L TAVKM D FRA NTG P Y GN H SLTVPCN G PALSLP LYP CDNVDFQVT T Y Y S N ICPN GA YQ GYGAP KGN F 566
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 373 A VESM L DDA A TA L G ID PV EI RL RN AAR EG D ----------- AN P LTGKRIY S AG L P E C L EK GR KIFE W EKRRA ecqn Q Q G 441
Cdd:PRK09800 567 A ITMA L AEL A EQ L Q ID QL EI IE RN RVH EG Q elkilgaigeg KA P TSVPSAA S CA L E E I L RQ GR EMIQ W SSPKP ---- Q N G 642
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 442 NLRR G V GVA CFSYT S NT w P v GVEI A GARLLMNQ DGT IN V Q SG ATE IG Q G A DTV FSQMV AE TVGV P VS DV R VIS T q DTD VT 521
Cdd:PRK09800 643 DWHI G R GVA IIMQK S GI - P - DIDQ A NCMIKLES DGT FI V H SG GAD IG T G L DTV VTKLA AE VLHC P PQ DV H VIS G - DTD HA 719
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 522 P FD P GA F AS RQSYVAAP A L R S AA LL L K EKI IA H A A V ML HQSAMNLT L IKGHI V LVERP E epl M S LK D L A MDA fyhp E R G - 600
Cdd:PRK09800 720 L FD K GA Y AS SGTCFSGN A A R L AA EN L R EKI LF H G A Q ML GEPVADVQ L ATPGV V RGKKG E --- V S FG D I A HKG ---- E T G t 792
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 601 -- G Q L SAES S IK T TTNPPAF G CT F VDLT V DIALCKVTINRILNVH D S G HIL NP L LA E GQ VH G GMGMG IG WALF EE M I I DA 678
Cdd:PRK09800 793 gf G S L VGTG S YI T PDFAFPY G AN F AEVA V NTRTGEIRLDKFYALL D C G TPV NP E LA L GQ IY G ATLRA IG HSMS EE I I Y DA 872
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446310295 679 K s G VVRNPN L LD Y KM P TMP D L P QLES A F - V EINEPQSAY G H KS LG E PPIIPV A A AI RN A VKM A T G VAINTLPL TP KRL 755
Cdd:PRK09800 873 E - G HPLTRD L RS Y GA P KIG D I P RDFR A V l V PSDDKVGPF G A KS IS E IGVNGA A P AI AT A IHD A C G IWLREWHF TP EKI 949
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
422-700
9.29e-93
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 290.98
E-value: 9.29e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 422 K GRKIFEWEK RRAE CQNQ - Q GN LR RG V G V A CFSYT S NTW P VGVEI AGA RLLM N Q DG TIN V QS G A TE I GQG AD T VFS Q MV A 500
Cdd:pfam20256 1 K ALELSDYDE RRAE QAEF n R GN RK RG I G I A PYVEG S GLG P GALNQ AGA LVRL N P DG SVT V YT G G TE M GQG LE T KLA Q IA A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 501 E TV G V P VS DVRV IST q DTD VT P FDP G AF ASR QSY V AAP A LRS AA LL L K E KIIAH AA VM L HQ S AMN L TLIK G HIVLVER P E 580
Cdd:pfam20256 81 E AL G I P PE DVRV VEG - DTD TV P NGG G TG ASR STD V GGN A VLL AA EK L R E RLLKI AA HL L EA S PED L EFED G KVYVKGD P R 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 581 E pl MSLKD LA MD A F yhp ER G GQ LSA ESS ----- IK T TTN PP ---- AF G CTFVDLT VD IALCK V TIN R ILN VHD S G HIL NP 651
Cdd:pfam20256 160 S -- VTFAE LA AA A Y --- GE G VG LSA TGF ytppd DE T GQG PP fayy PY G AHAAEVE VD PETGE V RVL R YVA VHD C G RVI NP 234
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 446310295 652 LLA EGQ VH GG MGM GIG W AL F EE MII D a KS G VVRNPN L L DYK M PT MP D L P 700
Cdd:pfam20256 235 AIV EGQ IE GG FVQ GIG L AL M EE LVY D - ED G QLLTAS L M DYK I PT AA D I P 282
MoCoBD_1
pfam02738 Molybdopterin cofactor-binding domain;
170-397
1.54e-88
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain]
Cd Length: 244
Bit Score: 278.57
E-value: 1.54e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 170 G N V QQTIDA AD YQ V Q G H Y Q T PVIQ H CH ME SVTS LA - WMED D S R I T IV SSTQ I PH I VRR V V GQA L D IP WSC VRVI K P F VGG 248
Cdd:pfam02738 16 G D V EAAFAE AD HV V E G E Y R T GRQE H FY ME TRAA LA v PDDE D G R L T VY SSTQ G PH L VRR L V ARV L G IP ENK VRVI V P R VGG 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 249 GFG N K - Q DVL EE PM AA FLTS K L G G i PVK VS L S REE CF LAT RT RH A F T I DGQM G VNR DG TLKGYSL D VLSNT GAYA SHGHS 327
Cdd:pfam02738 96 GFG G K t Q SYP EE AL AA LAAR K T G R - PVK WV L D REE DM LAT GH RH P F L I KYKV G ADK DG KILALDV D LYADG GAYA DLSPA 174
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 328 IASAGGNKVAYL Y PRCAYAYSSKTC YTN L P SA GA M RG Y G A PQ VV FA V E SML D DA A TA LG I DP V E I R L RN A 397
Cdd:pfam02738 175 VPERALSHLDGP Y KIPNVRVDGRAV YTN T P PN GA F RG F G R PQ GM FA L E RLM D EL A EE LG M DP L E L R R RN L 244
PLN02906
PLN02906 xanthine dehydrogenase
2-755
2.26e-71
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain]
Cd Length: 1319
Bit Score: 254.62
E-value: 2.26e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 2 EAREA TA T G ESCMRVD A IAK VTG R A R Y T DD YV M - AGMCY A KY V R S PIA H GYAV SI N D EQ A R S L PG VLA IF TWE DVP --- D 77
Cdd:PLN02906 558 TVKQG TA V G QPEVHLS A ELQ VTG E A E Y A DD IP M p PNTLH A AL V L S TKP H ARIL SI D D SE A K S S PG FAG IF LAK DVP gdn M 637
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 78 I pfata G HAW t L DE nkrdtad RALL T RH V RHH G DAVAI VVA RDELT A EK AA QL V SI E WQ ELP V I TTP E A A L ae D A API H N 157
Cdd:PLN02906 638 I ----- G PVV - H DE ------- ELFA T DV V TCV G QVIGV VVA DTQEN A KA AA RK V KV E YE ELP A I LSI E E A I -- E A GSF H P 702
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 158 G gnll KQSTMST G N V QQTID -- AA D YQVQ G HY Q TPVIQ H CHM E SVT SL A W - MEDDSRITIV SSTQ I P HIVRRV V GQA L DI 234
Cdd:PLN02906 703 N ---- TERRLEK G D V ELCFA sg QC D RIIE G EV Q MGGQE H FYL E PNS SL V W t SDSGNEVHMI SSTQ A P QKHQKY V AHV L GL 778
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 235 P W S C V RVIKPFV GGGFG N K qdvle E PMA AF LT ------ SK L GGI PVK VS L S R EECFLA T RT RHAF TIDGQM G VNRD G TLK 308
Cdd:PLN02906 779 P M S K V VCKTKRI GGGFG G K ----- E TRS AF IA aaaavp AY L LNR PVK LT L D R DVDMMI T GQ RHAF LGKYKV G FTNE G KIL 853
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 309 GYS L DVLS N T G AYASHGHSIA saggn KV A YLYPRCA Y AYSS ----- KT C Y TN L PS AG A M RG Y G A PQ VVFAV E SMLDDA A T 383
Cdd:PLN02906 854 ALD L EIYN N G G NSLDLSGAVL ----- ER A MFHSDNV Y EIPN vrivg NV C F TN F PS NT A F RG F G G PQ GMLIT E NWIQRI A V 928
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 384 A L GID P V EIR LR N AAR EG DANPL t G KRIYSAG LP ECLEKGRKIFEWE KRR A E C --- QNQQGNLR RGV GVA cfsytsntw P 460
Cdd:PLN02906 929 E L NKS P E EIR EM N FQG EG SVTHY - G QVLQHCT LP QLWDELKVSCDFL KRR E E V def NAKNRWKK RGV AMV --------- P 998
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 461 VGVE I AGARLL MNQ --------- DGT IN V QS G AT E I GQG AD T VFS Q MV A ETVGV P V S D V r V IS TQD TD VT P -- FDPG A F A 529
Cdd:PLN02906 999 TKFG I SFTTKF MNQ agalvhvyt DGT VL V TH G GV E M GQG LH T KVA Q VA A SAFNI P L S S V - F IS ETS TD KV P na SPTA A S A 1077
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 530 S RQS Y V A apalrs A A L LLK E K I I A HAAVM lhqsamnltlikghivlve RPEEPLM S LKD L AMDAFY hp E R g GQ LSA ---- 605
Cdd:PLN02906 1078 S SDM Y G A ------ A V L DAC E Q I K A RMEPV ------------------- ASKLNFS S FAE L VTACYF -- Q R - ID LSA hgfy 1129
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 606 ----- ESSI KT TTNP P ---- AF G CT F VD ----- LT V D IALCK V T I nriln V H D S G HIL NP LLAE GQ VH G GMGM G I GW ALF 671
Cdd:PLN02906 1130 itpdi GFDW KT GKGN P fnyf TY G AA F AE veidt LT G D FHTRR V D I ----- V M D L G YSI NP AIDI GQ IE G AFVQ G L GW VAL 1204
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 672 EE MII - DA KSGVV R NPN L L ----- D YK M P TMP D L P Q ------ L ES A fvei NE P QSAYGH K SL GEPP IIPV A A --- AI RN A 736
Cdd:PLN02906 1205 EE LKW g DA AHKWI R PGS L F tcgpg T YK I P SVN D I P F kfnvsl L KG A ---- PN P KAIHSS K AV GEPP FFLA A S vff AI KD A 1280
810 820
....*....|....*....|....*
gi 446310295 737 V K M A - TG V AINT ----- L P L TP K R L 755
Cdd:PLN02906 1281 I K A A r AE V GLHG wfpld T P A TP E R I 1305
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
10-755
3.90e-56
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 209.10
E-value: 3.90e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 10 G ESC M RVDAIAKV TG R A R Y T DD YVMAGM - CYAKY V R S PI AH GYA VSI NDEQ A R SLPGV LA I F T W E DVP D I pf A T A G hawt 88
Cdd:TIGR02969 577 G HPI M HLSGVKHA TG E A I Y C DD MPAVDQ e LFLTF V T S SR AH AKI VSI DLSE A L SLPGV VD I I T A E HLQ D A -- N T F G ---- 650
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 89 ldenkrdt ADRA L L T RH V RHH G DA V AI V V A RD E LT A EK AA QL V S I EWQE L - P V I T T P E A A laedaap I HNGGNLLKQSTM 167
Cdd:TIGR02969 651 -------- TEKL L A T DK V HCV G QL V CA V I A DS E VQ A KQ AA KH V K I VYRD L e P L I L T I E E A ------- I QHKSFFEPERKL 715
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 168 ST GNV QQTIDAA D YQVQ G HYQTPVIQ H CH ME SVTS L AWME - D D SRITIVS STQ I P HIVRRV V GQA L DI P WSC V RVIKPF V 246
Cdd:TIGR02969 716 EY GNV DEAFKVV D QILE G EIHMGGQE H FY ME TQSM L VVPK g E D QEMDVYV STQ F P KYIQDI V AAT L KL P VNK V MCHVRR V 795
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 247 GG G FG N K -- QDVLEEPMA AF LTS K l G G IP V KVS L S R E E CF L A T RT RH AFTIDGQM G VNR DG TLKGYSLDVL SN T G AYASH 324
Cdd:TIGR02969 796 GG A FG G K vg KTSIMAAIT AF AAN K - H G RA V RCT L E R G E DM L I T GG RH PYLGKYKA G FMN DG RIVALDVEHY SN G G SSLDE 874
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 325 GHSIASA G GN K V -- AY LY P -- RC ayay SSKT C Y TNLPS AG A M RG Y G A PQ VVFAV E SMLDDA A TAL G ID P VEI R LR N AAR E 400
Cdd:TIGR02969 875 SLWVIEM G LL K M dn AY KF P nl RC ---- RGWA C R TNLPS NT A F RG F G F PQ AGLIT E ACITEV A AKC G LS P EKV R TI N MYK E 950
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 401 G D AN P LT g KR I YSAG L PE C LEKGRKIFEWEK R RAECQ -- N QQGNLR - RG VG V ACFSYTSNTWP V GVEI A G A RLLMNQ DG T 477
Cdd:TIGR02969 951 I D QT P YK - QE I NAKN L FQ C WRECMAKSSYSE R KVAVE kf N AENYWK k RG LA V IPLKFPVGLGS V AMGQ A A A LVHIYL DG S 1029
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 478 IN V QS G AT E I GQG AD T VFS Q M V AETVGV P V S D V RVIS T QDTD V tpfd P GAF AS RQ S Y VA --- AP A LRS A A - L LLK -- E K I 551
Cdd:TIGR02969 1030 VL V TH G GI E M GQG VH T KMI Q V V SRELKM P M S N V HLRG T STET V ---- P NTN AS GG S V VA dln GL A VKD A C q T LLK rl E P I 1105
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 552 I A haavmlhqsamnltlikghivlverp EE P LMSL KD L A MD AF yhp ERGGQ LSA ------- ES S I --- K TTTN P PAF --- 618
Cdd:TIGR02969 1106 I S -------------------------- KN P QGTW KD W A QT AF --- DQSIS LSA vgyfrgy ES N I nwe K GEGH P FEY fvy 1156
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 619 -- G C TF V D --- LT V D IALCKVT I nriln V H D S GH IL NP L L AE GQV H G GMGM G I G WALF EE MIIDAK s G VV -- R N PN ll D Y 691
Cdd:TIGR02969 1157 ga A C SE V E idc LT G D HKNIRTD I ----- V M D V GH SI NP A L DI GQV E G AFIQ G M G LYTI EE LSYSPQ - G IL ys R G PN -- Q Y 1228
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446310295 692 K M P TMP D L P - Q L ESA F VEIN E - PQSA Y GH K S LGE PPII --- P V AA AI RN AV KM A ------ T G VAIN T L PLTP KRL 755
Cdd:TIGR02969 1229 K I P AIC D I P t E L HIS F LPPS E h SNTL Y SS K G LGE SGVF lgc S V FF AI HD AV RA A rqergl S G PWKL T S PLTP EKI 1303
PLN00192
PLN00192 aldehyde oxidase
2-740
1.07e-41
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain]
Cd Length: 1344
Bit Score: 164.50
E-value: 1.07e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 2 E AR E ATAT GE SCMR V D A IAKVT G R A R Y T DD YVMAGM C - Y AKYVR S PIAHGYAVS I NDEQARSLP GVLA IF T WE D V P dipf 80
Cdd:PLN00192 572 E NN E YHPV GE PIKK V G A ALQAS G E A V Y V DD IPSPKN C l Y GAFIY S TKPLARVKG I KFKSNLVPQ GVLA VI T FK D I P ---- 647
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 81 a TA G hawtld E N --- K RDTADRA L LTRH V RHH - G DAV A I VVA RDELT A EK AA Q L VSI E WQ ---- E L P VI T TPE A alaeda 152
Cdd:PLN00192 648 - KG G ------ Q N igs K TIFGPEP L FADE V TRC a G QRI A L VVA DTQKH A DM AA N L AVV E YD tenl E P P IL T VED A ------ 714
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 153 apihnggnl L K Q S TM ---------- ST G NVQQTIDA AD YQVQGHYQTPVI Q - HCH ME SV T S LA WMED D SR I TIV SSTQ I P 221
Cdd:PLN00192 715 --------- V K R S SL fevppflypk PV G DISKGMAE AD HKILSAEIKLGS Q y YFY ME TQ T A LA LPDE D NC I VVY SSTQ C P 785
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 222 HI V RR V VGQA L D IP WSC VRVI KPF VGGGFG N K Q d V LEE P M A --- A FLTS KL GG i PV KVS L S R EECFLATRT RH AFT I DGQ 298
Cdd:PLN00192 786 EY V HS V IARC L G IP EHN VRVI TRR VGGGFG G K A - V KSM P V A tac A LAAF KL QR - PV RMY L N R KTDMIMAGG RH PMK I TYS 863
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 299 M G VNR DG TLKGYS LD V L S N T G AYASHGHSIAS agg N KVAY L -- Y PRC A YAYSS K T C Y TNL P S AG AMR GY G AP Q VVFAV E S 376
Cdd:PLN00192 864 V G FKS DG KITALH LD I L I N A G ISPDISPIMPR --- N IIGA L kk Y DWG A LSFDI K V C K TNL S S RS AMR AP G EV Q GSYIA E A 940
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 377 MLDDA A TA L GI D PVEI R LR N AA reg DANP L tg K RI Y SAGLP E CL E KGRKIF e W E K -------- R R A E CQNQ -- QG N LRRG 446
Cdd:PLN00192 941 IIEHV A ST L SM D VDSV R KI N LH --- TYES L -- K LF Y GDSAG E PS E YTLPSI - W D K lasssefk Q R T E MVKE fn RS N KWKK 1014
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 447 V G VAC ---- FSYTSNTW P VG V E I agarll MN q DG T I N V QS G AT EIGQG AD T VFS QM V A -------- ETVGVPVSDV RVI S 514
Cdd:PLN00192 1015 R G ISR vpiv HEVMLRPT P GK V S I ------ LS - DG S I A V EV G GI EIGQG LW T KVK QM A A fglgmikc DGGEDLLDKI RVI Q 1087
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 515 tqd T D VTPFDP G A F -- A S RQ S YVAAP A L R SAALL L K E K iiahaavm L HQSAMN L TLIK G HIVLVERPEEPL M SLKD L AMD 592
Cdd:PLN00192 1088 --- S D TLSMIQ G G F ta G S TT S ESSCE A V R LCCVI L V E R -------- L KPIKER L QEQM G SVTWDMLISQAY M QSVN L SAS 1156
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 593 AF Y H P E rggqlsaessi KTTTNPPAF G CTFVDLT VD IALCKV TI N R ILNVH D S G HI LNP LLAE GQ VH G GMGM GIG WALF E 672
Cdd:PLN00192 1157 SY Y T P D ----------- PSSMEYLNY G AAVSEVE VD LLTGET TI L R SDIIY D C G QS LNP AVDL GQ IE G AFVQ GIG FFML E 1225
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446310295 673 E MIIDAK s G V V RNPNLLD YK M PT MPDL P Q les A F - VEI N ep Q S AYGH ------ K SL GEPP II --- P V AA A I R N A VKM A 740
Cdd:PLN00192 1226 E YTTNSD - G L V VTDGTWT YK I PT VDTI P K --- Q F n VEI L -- N S GHHK krvlss K AS GEPP LL laa S V HC A T R A A IRE A 1297
Ald_Xan_dh_C
pfam01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
23-139
5.82e-39
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain]
Cd Length: 107
Bit Score: 139.68
E-value: 5.82e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 23 TG R A R Y T DD YVMA G MC Y AKY VRS P IAH GYA VSI NDEQ A RS LPGV L A IF T WE D V P DIPFATAGHA wtldenkrdt A D RALL 102
Cdd:pfam01315 1 TG E A V Y V DD IPAP G NL Y GAF VRS T IAH AKI VSI DTSA A LA LPGV V A VI T AK D L P GGNYNIGPIP ---------- L D PLFA 70
90 100 110
....*....|....*....|....*....|....*..
gi 446310295 103 T RH VRH H G DAV A I VVA R DE L TA EK AA Q LV SI E WQ ELP 139
Cdd:pfam01315 71 T DK VRH V G QPI A A VVA D DE E TA RR AA K LV KV E YE ELP 107
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
23-139
2.77e-37
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 134.95
E-value: 2.77e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446310295 23 TG R ARY T DD YVMA GM CY A KY VRSP I AH GYAV SI NDEQ AR SL PGV L A IF T WE DVP DIPFATAGH awtldenkrd TADRA L L 102
Cdd:smart01008 1 TG E ARY G DD IRLP GM LH A AV VRSP V AH ARIK SI DTSA AR AM PGV V A VL T AK DVP GLNDFGPLG ---------- PDEPV L A 70
90 100 110
....*....|....*....|....*....|....*..
gi 446310295 103 TRH VR HH G DA VA I VVA RD E LT A EK AA QL V SI E WQ ELP 139
Cdd:smart01008 71 DDK VR YV G QP VA A VVA ET E EA A RD AA EA V KV E YE ELP 107
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
