|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 708.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFE-NNQVTIDASKE 79
Cdd:PRK09369 1 MDKLVIEGGKPLSGEVTISGAKNAALPILAASLLA-EEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDgNGTVTIDASNI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 80 LNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIY 159
Cdd:PRK09369 80 NNTEAPYELVKKMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDLHLKGLEALGAEIEIEHGYVEAKADGRLKGAHIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 160 LDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGT 239
Cdd:PRK09369 160 LDFPSVGATENILMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKISGAGTDTITIEGVERLHGAEHTVIPDRIEAGT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 240 FMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQAD 319
Cdd:PRK09369 240 FLVAAAITGGDVTIRGARPEHLEAVLAKLREAGAEIEEGEDGIRVDMPGRLKAVDIKTAPYPGFPTDMQAQFMALLTQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 320 GTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRG 399
Cdd:PRK09369 320 GTSVITETIFENRFMHVPELIRMGADIEVDGHTAVVRGVEKLSGAPVMATDLRASASLVLAGLVAEGTTIVDRIYHLDRG 399
|
410
....*....|....*...
gi 446333413 400 YVDFHKKLAALGATIERV 417
Cdd:PRK09369 400 YERIEEKLRALGADIERV 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 700.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVF-ENNQVTIDASKE 79
Cdd:COG0766 1 MDKLIIEGGKPLSGEVRISGAKNAALPILAAALLT-DGPVTLRNVPDLSDVRTMLELLESLGVKVERdDGGTLTIDASNI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 80 LNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGeLKGAKIY 159
Cdd:COG0766 80 NSTEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHGYIEARAGR-LKGARIY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 160 LDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGT 239
Cdd:COG0766 159 LDFPSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 240 FMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQAD 319
Cdd:COG0766 239 FLVAAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 320 GTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDlraaaalilaglVSEGYTRVTELKHLDRG 399
Cdd:COG0766 319 GTSVITETVFENRFMHVDELNRMGADIKLDGHTAIVRGVTKLSGAPVMATDlragaalvlaglAAEGETVIDNIYHIDRG 398
|
410
....*....|....*...
gi 446333413 400 YVDFHKKLAALGATIERV 417
Cdd:COG0766 399 YENLEEKLRALGADIERV 416
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
12-410 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 627.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 12 LNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFEN-NQVTIDASKELNIEAPFEYVR 90
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLT-DEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGeNTLVIDASNINSTEAPYELVR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 91 KMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATEN 170
Cdd:cd01555 80 KMRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKAAGRLKGARIYLDFPSVGATEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 171 IMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGTFMVAAAITGGD 250
Cdd:cd01555 160 IMMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 251 ILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDK-LKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVF 329
Cdd:cd01555 240 ITVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVDGDGGrLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 330 ENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAA 409
Cdd:cd01555 320 ENRFMHVDELNRMGADIKVEGNTAIIRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRA 399
|
.
gi 446333413 410 L 410
Cdd:cd01555 400 L 400
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
1-416 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 612.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL 80
Cdd:TIGR01072 1 MDKLVVEGGKPLSGEVTISGAKNAALPIIAATLLT-DEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNIN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 81 NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL 160
Cdd:TIGR01072 80 STEAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIVIEDGYVYASAKGRLVGAHIVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 161 DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGTF 240
Cdd:TIGR01072 160 DKVSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 241 MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIG-PDKLKAVDIKTMPHPGFPTDMQSQMMALLLQAD 319
Cdd:TIGR01072 240 LVAAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDMrQKRLKAVDIETLPYPGFPTDLQAQFMALLSQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 320 GTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRG 399
Cdd:TIGR01072 320 GTSVITETVFENRFMHVDELIRMGANIKLEGNTAVIHGVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRG 399
|
410
....*....|....*..
gi 446333413 400 YVDFHKKLAALGATIER 416
Cdd:TIGR01072 400 YEDLEEKLRALGAKIER 416
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
7-407 |
8.72e-132 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 385.88 E-value: 8.72e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 7 RGGKRLNGTVRVEG-AKNAVLPIIAAALLAsdGKNVLSEVPVLSDVYTINEVLRHLNAEVVFE--NNQVTIDASKELNIE 83
Cdd:pfam00275 1 TGGSRLSGEVKIPGsKSNSHRALILAALAA--GESTITNLLDSDDTLTMLEALRALGAEIIKLddEKSVVIVEGLGGSFE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 84 APFEYVRKMRASVQVMGPLLARNGRAR--IALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVE---GELKGAKI 158
Cdd:pfam00275 79 APEDLVLDMGNSGTALRPLTGRLALQSgeVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAPLKvrgLRLGGIHI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 159 YLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGT-IRIEGVDKLYGGNHSIIPDRIEA 237
Cdd:pfam00275 159 DGDVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTELsITVKGGEKLPGQEYRVEGDRSSA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 238 GTFMVAAAITGGDILIENAVPEHLR---SITAKMEEMGVKIIEENEGVRVIGPDKL--KAVDIKTMPHPGFPTDMQSQMM 312
Cdd:pfam00275 239 AYFLVAAAITGGTVTVENVGINSLQgdeALLEILEKMGAEITQEEDADIVVGPPGLrgKAVDIRTAPDPAPTTAVLAAFA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 313 ALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGP-NSLQGAEVGAT-DLRAAAALILAGLVSEGYTRV 390
Cdd:pfam00275 319 EGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAvKELKGAEVDSYgDHRIAMALALAGLVAEGETII 398
|
410
....*....|....*..
gi 446333413 391 TELKHLDRGYVDFHKKL 407
Cdd:pfam00275 399 DDIECTDRSFPDFEEKL 415
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 708.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFE-NNQVTIDASKE 79
Cdd:PRK09369 1 MDKLVIEGGKPLSGEVTISGAKNAALPILAASLLA-EEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDgNGTVTIDASNI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 80 LNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIY 159
Cdd:PRK09369 80 NNTEAPYELVKKMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDLHLKGLEALGAEIEIEHGYVEAKADGRLKGAHIV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 160 LDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGT 239
Cdd:PRK09369 160 LDFPSVGATENILMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKISGAGTDTITIEGVERLHGAEHTVIPDRIEAGT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 240 FMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQAD 319
Cdd:PRK09369 240 FLVAAAITGGDVTIRGARPEHLEAVLAKLREAGAEIEEGEDGIRVDMPGRLKAVDIKTAPYPGFPTDMQAQFMALLTQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 320 GTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRG 399
Cdd:PRK09369 320 GTSVITETIFENRFMHVPELIRMGADIEVDGHTAVVRGVEKLSGAPVMATDLRASASLVLAGLVAEGTTIVDRIYHLDRG 399
|
410
....*....|....*...
gi 446333413 400 YVDFHKKLAALGATIERV 417
Cdd:PRK09369 400 YERIEEKLRALGADIERV 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 700.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVF-ENNQVTIDASKE 79
Cdd:COG0766 1 MDKLIIEGGKPLSGEVRISGAKNAALPILAAALLT-DGPVTLRNVPDLSDVRTMLELLESLGVKVERdDGGTLTIDASNI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 80 LNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGeLKGAKIY 159
Cdd:COG0766 80 NSTEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHGYIEARAGR-LKGARIY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 160 LDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGT 239
Cdd:COG0766 159 LDFPSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGT 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 240 FMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQAD 319
Cdd:COG0766 239 FLVAAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 320 GTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDlraaaalilaglVSEGYTRVTELKHLDRG 399
Cdd:COG0766 319 GTSVITETVFENRFMHVDELNRMGADIKLDGHTAIVRGVTKLSGAPVMATDlragaalvlaglAAEGETVIDNIYHIDRG 398
|
410
....*....|....*...
gi 446333413 400 YVDFHKKLAALGATIERV 417
Cdd:COG0766 399 YENLEEKLRALGADIERV 416
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
12-410 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 627.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 12 LNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFEN-NQVTIDASKELNIEAPFEYVR 90
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLT-DEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGeNTLVIDASNINSTEAPYELVR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 91 KMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATEN 170
Cdd:cd01555 80 KMRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKAAGRLKGARIYLDFPSVGATEN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 171 IMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGTFMVAAAITGGD 250
Cdd:cd01555 160 IMMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 251 ILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDK-LKAVDIKTMPHPGFPTDMQSQMMALLLQADGTSMITETVF 329
Cdd:cd01555 240 ITVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVDGDGGrLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIF 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 330 ENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAA 409
Cdd:cd01555 320 ENRFMHVDELNRMGADIKVEGNTAIIRGVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRA 399
|
.
gi 446333413 410 L 410
Cdd:cd01555 400 L 400
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
1-416 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 612.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL 80
Cdd:TIGR01072 1 MDKLVVEGGKPLSGEVTISGAKNAALPIIAATLLT-DEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNIN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 81 NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL 160
Cdd:TIGR01072 80 STEAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIVIEDGYVYASAKGRLVGAHIVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 161 DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGTF 240
Cdd:TIGR01072 160 DKVSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 241 MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIG-PDKLKAVDIKTMPHPGFPTDMQSQMMALLLQAD 319
Cdd:TIGR01072 240 LVAAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDMrQKRLKAVDIETLPYPGFPTDLQAQFMALLSQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 320 GTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRG 399
Cdd:TIGR01072 320 GTSVITETVFENRFMHVDELIRMGANIKLEGNTAVIHGVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRG 399
|
410
....*....|....*..
gi 446333413 400 YVDFHKKLAALGATIER 416
Cdd:TIGR01072 400 YEDLEEKLRALGAKIER 416
|
|
| PRK12830 |
PRK12830 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed |
1-417 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed
Pssm-ID: 183779 Cd Length: 417 Bit Score: 551.77 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL 80
Cdd:PRK12830 1 MEKIVINGGKPLSGEVTISGAKNSAVALIPAAILA-DGPVTLDGVPDISDVHSLVDILEELGGKVKRDGDTLEIDPTGIQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 81 NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEgELKGAKIYL 160
Cdd:PRK12830 80 SMPLPNGKVKSLRASYYFMGALLGRFKKAVVGLPGGCDLGPRPIDQHIKGFEALGAEVTNEGGAIYLKAD-ELKGAHIYL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 161 DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGTF 240
Cdd:PRK12830 159 DVVSVGATINIMLAAVKAKGRTVIENAAKEPEIIDVATLLNNMGANIKGAGTDVIRIEGVDELHGCRHTVIPDRIEAGTY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 241 MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG 320
Cdd:PRK12830 239 MILAAACGGGVTINNVIPEHLESFIAKLEEMGVRVEVNEDSIFVEKQGNLKAVDIKTLPYPGFATDLQQPLTPLLLKANG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 321 TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGY 400
Cdd:PRK12830 319 RSVVTDTIYEKRFKHVDELKRMGANIKVEGRSAIITGPSKLTGAKVKATDLRAGAALVIAGLMAEGVTEITNIEHIDRGY 398
|
410
....*....|....*..
gi 446333413 401 VDFHKKLAALGATIERV 417
Cdd:PRK12830 399 SNIIEKLKALGADIWRE 415
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
7-407 |
8.72e-132 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 385.88 E-value: 8.72e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 7 RGGKRLNGTVRVEG-AKNAVLPIIAAALLAsdGKNVLSEVPVLSDVYTINEVLRHLNAEVVFE--NNQVTIDASKELNIE 83
Cdd:pfam00275 1 TGGSRLSGEVKIPGsKSNSHRALILAALAA--GESTITNLLDSDDTLTMLEALRALGAEIIKLddEKSVVIVEGLGGSFE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 84 APFEYVRKMRASVQVMGPLLARNGRAR--IALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVE---GELKGAKI 158
Cdd:pfam00275 79 APEDLVLDMGNSGTALRPLTGRLALQSgeVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREGYNYAPLKvrgLRLGGIHI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 159 YLDFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGT-IRIEGVDKLYGGNHSIIPDRIEA 237
Cdd:pfam00275 159 DGDVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTELsITVKGGEKLPGQEYRVEGDRSSA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 238 GTFMVAAAITGGDILIENAVPEHLR---SITAKMEEMGVKIIEENEGVRVIGPDKL--KAVDIKTMPHPGFPTDMQSQMM 312
Cdd:pfam00275 239 AYFLVAAAITGGTVTVENVGINSLQgdeALLEILEKMGAEITQEEDADIVVGPPGLrgKAVDIRTAPDPAPTTAVLAAFA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 313 ALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGP-NSLQGAEVGAT-DLRAAAALILAGLVSEGYTRV 390
Cdd:pfam00275 319 EGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAvKELKGAEVDSYgDHRIAMALALAGLVAEGETII 398
|
410
....*....|....*..
gi 446333413 391 TELKHLDRGYVDFHKKL 407
Cdd:pfam00275 399 DDIECTDRSFPDFEEKL 415
|
|
| EPT-like |
cd01554 |
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine ... |
12-410 |
2.11e-86 |
|
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.
Pssm-ID: 238795 Cd Length: 408 Bit Score: 269.47 E-value: 2.11e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 12 LNGTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKELNIEAP---FEY 88
Cdd:cd01554 1 LHGIIRVPGDKSISHRSLIFASLA-EGETKVYNILRGEDVLSTMQVLRDLGVEIEDKDGVITIQGVGMAGLKAPqnaLNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 89 VRKMRASVQVMGPLLARNGRarIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEA--YVEGELKGAKIYLD-FPSV 165
Cdd:cd01554 80 GNSGTAIRLISGVLAGADFE--VELFGDDSLSKRPMDRVTLPLKKMGASISGQEERDLPplLKGGKNLGPIHYEDpIASA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 166 GATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGTFMVAAA 245
Cdd:cd01554 158 QVKSALMFAALLAKGETVIIEAAKEPTINHTENMLQTFGGHISVQGTKKIVVQGPQKLTGQKYVVPGDISSAAFFLVAAA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 246 ITGGDILIENAVP-EHLRSITAKMEEMGVKiIEENEGVRVIGPDKLKAVDIKTMPHPgFPTDMQSQMMALLLQADGTSMI 324
Cdd:cd01554 238 IAPGRLVLQNVGInETRTGIIDVLRAMGAK-IEIGEDTISVESSDLKATEICGALIP-RLIDELPIIALLALQAQGTTVI 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 325 TETVF------ENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGAT-DLRAAAALILAGLVSEGYTRVTELKHLD 397
Cdd:cd01554 316 KDAEElkvketDRIFVVADELNSMGADIEPTADGMIIKGKEKLHGARVNTFgDHRIGMMTALAALVADGEVELDRAEAIN 395
|
410
....*....|...
gi 446333413 398 RGYVDFHKKLAAL 410
Cdd:cd01554 396 TSYPSFFDDLESL 408
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
1-366 |
7.78e-22 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 97.08 E-value: 7.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAK---NAVLpiIAAALlaSDGKNVLSEVPVLSDV-YTINeVLRHLNAEV-VFENNQVTID 75
Cdd:COG0128 1 MSSLTIAPPSPLKGTVRVPGSKsisHRAL--LLAAL--AEGESTIRNLLESDDTlATLE-ALRALGAEIeELDGGTLRVT 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 76 aSKELNIEAPFEYVR------KMRasvqVMGPLLA-RNGRARIAlpGGCAIGSRPIDQHLKGFEAMGAKVQ-VGNGFVEA 147
Cdd:COG0128 76 -GVGGGLKEPDAVLDcgnsgtTMR----LLTGLLAlQPGEVVLT--GDESLRKRPMGRLLDPLRQLGARIEsRGGGYLPL 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 148 YVEG-ELKGAKIYLDfpsvgatENI---------MSAATLAKGTTILENAAKEPEI-VDLA-NFLNAMGAKVRGAGTGTI 215
Cdd:COG0128 149 TIRGgPLKGGEYEIP-------GSAssqfksallLAGPLAEGGLEITVTGELESKPyRDHTeRMLRAFGVEVEVEGYRRF 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 216 RIEGVDKLYGGNHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITA---KMEEMGVKIIEENEGVRVIGpDKLKA 292
Cdd:COG0128 222 TVPGGQRYRPGDYTVPGDISSAAFFLAAAAITGSEVTVEGVGLNSTQGDTGildILKEMGADIEIENDGITVRG-SPLKG 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 293 VDIktmphPG------FPTdmqsqMMALLLQADGTSMIT--------ETvfeNRF--MhVEEFRRMNADIKIEGRSVIMN 356
Cdd:COG0128 301 IDI-----DLsdipdeAPT-----LAVLAAFAEGTTRIRgaaelrvkES---DRIaaM-ATELRKLGADVEETEDGLIIE 366
|
410
....*....|
gi 446333413 357 GPNSLQGAEV 366
Cdd:COG0128 367 GGPKLKGAEV 376
|
|
| EPT_RTPC-like |
cd01553 |
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate ... |
232-410 |
2.25e-18 |
|
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats with a 4th slightly different domain inserted between the 2nd and 3rd repeat. They evidently share the same active site location, although the catalytic residues differ.
Pssm-ID: 238794 Cd Length: 211 Bit Score: 83.10 E-value: 2.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 232 PDRIEAGTFMVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIG-----------PDKLKAVDIKTMPH 300
Cdd:cd01553 8 GGGQILRSFLVLAAISGGPITVTGIRPDRAKPGLLRQHLTFLKALEKICGATVEGgelgsdrisfrPGTVRGGDVRFAIG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 301 P-GFPTDMQSQMMALLLQADGTSMITETVF----------ENRFMHVEEFRRMNADIKIE------------GRSVIMNG 357
Cdd:cd01553 88 SaGSCTDVLQTILPLLLFAKGPTRLTVTGGtdnpsappadFIRFVLEPELAKIGAHQEETllrhgfypagggVVATEVSP 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446333413 358 PNSLQGAEVGATdlraaaaliLAGLVSEGYTRVTELKHLDRGYVDFHKKLAAL 410
Cdd:cd01553 168 VEKLNTAQLRQL---------VLPMLLASGAVEFTVAHPSCHLLTNFAVLEAL 211
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
14-412 |
4.54e-18 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 85.79 E-value: 4.54e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 14 GTVRVEGAKNAVLPIIAAALLAsDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKELNIEAPFeyvrKMR 93
Cdd:TIGR01356 1 GEIRAPGSKSITHRALILAALA-EGETRVRNLLRSEDTLATLDALRALGAKIEDGGEVAVIEGVGGKEPQAEL----DLG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 94 ASVQVMGPLLARNGRAR--IALPGGCAIGSRPIDQHLKGFEAMGAKV--QVGNGFVEAYVEGELKGAKIYLDfPSVGA-- 167
Cdd:TIGR01356 76 NSGTTARLLTGVLALADgeVVLTGDESLRKRPMGRLVDALRQLGAEIssLEGGGSLPLTISGPLPGGIVYIS-GSASSqy 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 168 -TENIMSAATL-AKGTTIL-ENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRIEAGTFMVAA 244
Cdd:TIGR01356 155 kSALLLAAPALqAVGITIVgEPLKSRPYIEITLDLLGSFGVEVERSDGRKIVVPGGQKYGPQGYDVPGDYSSAAFFLAAA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 245 AITGGDILIENAVPEHLR---SITAKMEEMGVKIIEENEGVRVIGPDKLKAV--DIKTMPHPgFPTdmqsqMMALLLQAD 319
Cdd:TIGR01356 235 AITGGRVTLENLGINPTQgdkAIIIVLEEMGADIEVEEDDLIVEGASGLKGIkiDMDDMIDE-LPT-----LAVLAAFAE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 320 GTSMIT--------ETvfeNRFMHV-EEFRRMNADIKIEGRSVIMNGPNSLQGAEVGA-TDLRAAAALILAGLVSEGYTR 389
Cdd:TIGR01356 309 GVTRITgaeelrvkES---DRIAAIaEELRKLGVDVEEFEDGLYIRGKKELKGAVVDTfGDHRIAMAFAVAGLVAEGEVL 385
|
410 420
....*....|....*....|...
gi 446333413 390 VTELKHLDRGYVDFHKKLAALGA 412
Cdd:TIGR01356 386 IDDPECVAKSFPSFFDVLERLGA 408
|
|
| EPSP_synthase |
cd01556 |
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase ... |
12-410 |
5.71e-15 |
|
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.
Pssm-ID: 238797 Cd Length: 409 Bit Score: 76.06 E-value: 5.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 12 LNGTVRVEGAKN----AvlpIIAAALlaSDGKNVLsEVPVLSD--VYTINeVLRHLNAEVVFENNQVTIDASKELNieAP 85
Cdd:cd01556 1 LSGEITVPGSKSishrA---LLLAAL--AEGESRI-ENLLDSDdtLATLE-ALRALGAKIEEEGGTVEIVGGGGLG--LP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 86 FEYVRKMRASVQVMGPL--LARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKV--QVGNGFVEAYVEGELKGAKIYLD 161
Cdd:cd01556 72 PEAVLDCGNSGTTMRLLtgLLALQGGDSVLTGDESLRKRPMGRLVDALRQLGAEIegREGGGYPPLIGGGGLKGGEVEIP 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 162 FPS----VGAtenIMSAATLAKGTTILENAAKEPEI-VDL-ANFLNAMGAKVRGAGTGTIRIEGVDKLYGGNHSIIPDRI 235
Cdd:cd01556 152 GAVssqfKSA---LLLAAPLAEGPTTIIIGELESKPyIDHtERMLRAFGAEVEVDGYRTITVKGGQKYKGPEYTVEGDAS 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 236 EAGTFMVAAAITGGDILIENaVPEHL--RSITAKMEEMGVKIIEENEG-VRVIGPDKLKAVDIKTMPHPG-FPTdmqsqm 311
Cdd:cd01556 229 SAAFFLAAAAITGSEIVIKN-VGLNSgdTGIIDVLKEMGADIEIGNEDtVVVESGGKLKGIDIDGNDIPDeAPT------ 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 312 MALL-LQADGTSMIT--------ETvfeNRF--MhVEEFRRMNADIKIEGRSVIMNGPNS-LQGAEV-GATDLRAAAALI 378
Cdd:cd01556 302 LAVLaAFAEGPTRIRnaaelrvkES---DRIaaM-ATELRKLGADVEETEDGLIIEGGPLkGAGVEVyTYGDHRIAMSFA 377
|
410 420 430
....*....|....*....|....*....|..
gi 446333413 379 LAGLVSEGYTRVTELKHLDRGYVDFHKKLAAL 410
Cdd:cd01556 378 IAGLVAEGGVTIEDPECVAKSFPNFFEDLESL 409
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
1-351 |
2.47e-11 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 65.16 E-value: 2.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAKN----AvlpIIAAALlaSDGKNVLSEVPVLSDV-YTINeVLRHLNAEVvfENNQVTID 75
Cdd:PRK02427 2 MMMLLIIPPSPLSGTVRVPGSKSishrA---LLLAAL--AEGETTITNLLRSEDTlATLN-ALRALGVEI--EDDEVVVE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 76 ASKELNIEAPFEYV---------RKMrasvqvMGPLLARNGRARIAlpGGCAIGSRPIDQHLKGFEAMGAKVQVG-NGFV 145
Cdd:PRK02427 74 GVGGGGLKEPEDVLdcgnsgttmRLL------TGLLALQPGEVVLT--GDESLRKRPMGRLLDPLRQMGAKIEGRdEGYL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 146 EAYVEGELKGAKIYLDFPS----V-GAtenIMSAATLAKG---TTILENAAKEPEIVDLANFLNAMGAKVR---GAGTGT 214
Cdd:PRK02427 146 PLTIRGGKKGGPIEYDGPVssqfVkSL---LLLAPLFAEGdteTTVIEPLPSRPHTEITLRMLRAFGVEVEnveGWGYRR 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 215 IRIEGVDKLYGGNHSIIPDRIEAGTFMVAAAITGG-DILIENaVPE-------HLRSItakMEEMGVKIIEENEGVR--- 283
Cdd:PRK02427 223 IVIKGGQRLRGQDITVPGDPSSAAFFLAAAAITGGsEVTITN-VGLnstqggkAIIDV---LEKMGADIEIENEREGgep 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 284 ----VIGPDKLKAVDIkTMPHPG--FPTdmqsqMMALLLQADGTSMIT--------ETvfeNRF--MhVEEFRRMNADIK 347
Cdd:PRK02427 299 vgdiRVRSSELKGIDI-DIPDIIdeAPT-----LAVLAAFAEGTTVIRnaeelrvkET---DRIaaM-ATELRKLGAEVE 368
|
410
....*....|.
gi 446333413 348 -------IEGR 351
Cdd:PRK02427 369 etedgliITGG 379
|
|
| PLN02338 |
PLN02338 |
3-phosphoshikimate 1-carboxyvinyltransferase |
1-344 |
5.16e-07 |
|
3-phosphoshikimate 1-carboxyvinyltransferase
Pssm-ID: 177972 [Multi-domain] Cd Length: 443 Bit Score: 51.67 E-value: 5.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 1 MEKIIVRGGKRLNGTVRVEGAK---NAVLpiIAAALlaSDGKNVLSEVPVLSDVYTINEVLRHLNAEVV--FENNQVTID 75
Cdd:PLN02338 1 AEEITLQPIKEISGTVKLPGSKslsNRIL--LLAAL--SEGTTVVDNLLDSDDIRYMLGALKTLGLNVEedSENNRAVVE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 76 ASKelnieAPFEYVRKMRASVQV--------MGPLLA----RNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNG 143
Cdd:PLN02338 77 GCG-----GKFPVSGDSKEDVELflgnagtaMRPLTAavtaAGGNASYVLDGVPRMRERPIGDLVDGLKQLGADVECTLG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 144 F----VEAYVEGELKGAKIYLD--FPSVGATENIMsAATLAKGT---TILENAAKEPEIVDLANFLNAMGAKV-RGAGTG 213
Cdd:PLN02338 152 TncppVRVNAAGGLPGGKVKLSgsISSQYLTALLM-AAPLALGDveiEIVDKLISVPYVEMTLKLMERFGVSVeHSDSWD 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 214 TIRIEGVDKLYG-GNHSIIPDRIEAGTFMVAAAITGGDILIENAVPEHLRSITA---KMEEMGVKIIEENEGVRVIGPD- 288
Cdd:PLN02338 231 RFFIKGGQKYKSpGNAYVEGDASSASYFLAGAAITGGTVTVEGCGTTSLQGDVKfaeVLEKMGAKVEWTENSVTVTGPPr 310
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446333413 289 ------KLKAVDI--KTMPhpgfptDMQSQMMALLLQADGTSMITEtVFENRfmhVEEFRRMNA 344
Cdd:PLN02338 311 dafggkHLKAIDVnmNKMP------DVAMTLAVVALFADGPTAIRD-VASWR---VKETERMIA 364
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
171-366 |
2.00e-06 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 49.76 E-value: 2.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 171 IMSAAtLAKGTTILENAAKEPEIVDLANFLNAMGAKVRgagTGTIRIEGVdklyGGNHSIIPDRI----EAGT----FMV 242
Cdd:PRK02427 30 LLLAA-LAEGETTITNLLRSEDTLATLNALRALGVEIE---DDEVVVEGV----GGGGLKEPEDVldcgNSGTtmrlLTG 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 243 AAAITGGDILIENavPEHLRS-----ITAKMEEMGVKIIEENEG---VRVIGPDKLKAVDIKtmphpgfpTDMQSQ---- 310
Cdd:PRK02427 102 LLALQPGEVVLTG--DESLRKrpmgrLLDPLRQMGAKIEGRDEGylpLTIRGGKKGGPIEYD--------GPVSSQfvks 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446333413 311 -MMALLLQADG--TSMITETV-----FEnrfMHVEEFRRMNADIKIEG----RSVIMNGPNSLQGAEV 366
Cdd:PRK02427 172 lLLLAPLFAEGdtETTVIEPLpsrphTE---ITLRMLRAFGVEVENVEgwgyRRIVIKGGQRLRGQDI 236
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
132-269 |
2.26e-06 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 49.76 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 132 EAMGAKVQVGNGFVEAYVEG-------ELKGakIYLDFPSVG-ATENIMSAATLAKGTTILENAA----KEPE-IVDLAN 198
Cdd:PRK02427 281 EKMGADIEIENEREGGEPVGdirvrssELKG--IDIDIPDIIdEAPTLAVLAAFAEGTTVIRNAEelrvKETDrIAAMAT 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 199 FLNAMGAKVRgAGTGTIRIEGVDKLYG----GNHsiipdRIeAGTFMVAAAITGGDILIENA--V-------PEHLRSIT 265
Cdd:PRK02427 359 ELRKLGAEVE-ETEDGLIITGGPLAGVvdsyGDH-----RI-AMAFAIAGLAAEGPVTIDDPecVaksfpdfFEDLASLG 431
|
....
gi 446333413 266 AKME 269
Cdd:PRK02427 432 ANIE 435
|
|
| PRK14806 |
PRK14806 |
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; ... |
88-295 |
4.47e-04 |
|
bifunctional cyclohexadienyl dehydrogenase/ 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 237820 [Multi-domain] Cd Length: 735 Bit Score: 42.67 E-value: 4.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 88 YVRKMRASVQVMGPLLArnGRA-RIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGN-GFVEAYVEGELKGAKIYLDFPSv 165
Cdd:PRK14806 390 YMGNSGTSMRLLSGLLA--AQSfDSVLTGDASLSKRPMERVAKPLREMGAVIETGEeGRPPLSIRGGQRLKGIHYDLPM- 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446333413 166 gATENIMSAATLA----KGTTilenAAKEPEIV--DLANFLNAMGAKVRGAGTgTIRIEGVDKLYGGNHSIIPDRIEAGT 239
Cdd:PRK14806 467 -ASAQVKSCLLLAglyaEGET----SVTEPAPTrdHTERMLRGFGYPVKVEGN-TISVEGGGKLTATDIEVPADISSAAF 540
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446333413 240 FMVAAAITGG-DILIEN--------AVPEHLRSitakmeeMGVKIIEENEGVR--------VIGPDKLKAVDI 295
Cdd:PRK14806 541 FLVAASIAEGsELTLEHvginptrtGVIDILKL-------MGADITLENEREVggepvadiRVRGARLKGIDI 606
|
|
| |
