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Conserved domains on  [gi|446358913|ref|WP_000436768|]
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MULTISPECIES: proline dehydrogenase family protein [Bacillus]

Protein Classification

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; proline dehydrogenase family protein; proline dehydrogenase family protein( domain architecture ID 11423475)

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase catalyzes the two-step oxidation of proline to glutamate; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase catalyzes the two-step oxidation of proline to glutamate; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PutA super family cl33919
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 27-277 8.22e-97

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


The actual alignment was detected with superfamily member COG0506:

Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 306.20  E-value: 8.22e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  27 LRFGAGRFVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGKEGLD-SQLSLKMTSMGLD 105
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 106 ISD-------EIVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDMED 173
Cdd:COG0506  189 YSPaqrervvEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDR 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 174 LNA------YNPNLRLVKGAYKEPEEV----------AFPDKKDVDDNYKKIIKMHLLNGN--YTAIASHDEAIIEYTKK 235
Cdd:COG0506  269 LAAlarrggRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446358913 236 LAEEHNIPRDQFEFQMLYGIRNERQLELVKE-GYKMRVYVPYG 277
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVV 391
 
Name Accession Description Interval E-value
PutA COG0506
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 27-277 8.22e-97

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 306.20  E-value: 8.22e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  27 LRFGAGRFVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGKEGLD-SQLSLKMTSMGLD 105
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 106 ISD-------EIVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDMED 173
Cdd:COG0506  189 YSPaqrervvEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDR 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 174 LNA------YNPNLRLVKGAYKEPEEV----------AFPDKKDVDDNYKKIIKMHLLNGN--YTAIASHDEAIIEYTKK 235
Cdd:COG0506  269 LAAlarrggRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446358913 236 LAEEHNIPRDQFEFQMLYGIRNERQLELVKE-GYKMRVYVPYG 277
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVV 391
Pro_dh pfam01619
Proline dehydrogenase;
43-298 4.24e-55

Proline dehydrogenase;


Pssm-ID: 426348 [Multi-domain]  Cd Length: 296  Bit Score: 180.77  E-value: 4.24e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   43 ATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGKE------GLDSQLSLKMTSMG--LDISD-----E 109
Cdd:pfam01619   1 ALKTIEKLRKQGYRFSLDMLGEAALTEADADRYLDAYLRAIDALGKAagpwplGPRPGISVKLSALHprYEPLErervmA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  110 IVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDMEDLNA------YN 178
Cdd:pfam01619  81 ELLERLRPLCRLAKELGVRLNIDAEEADRLDLTLDLFERLLAEpelrgWNGVGITLQAYLKDALAVLDWLLElarrrgRP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  179 PNLRLVKGAY--KEPEEVA--------FPDKKDVDDNYKKIIKMhLLNGN---YTAIASHDEAIIEYTKKLAEEHNIPRD 245
Cdd:pfam01619 161 LGVRLVKGAYwdSEIKRAQqggwpypvFTRKEATDANYEACARF-LLENHdriYPQFATHNARSVAAALALAEELGIPPR 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446358913  246 QFEFQMLYGIRNERQLELVKEGYKMRVYVPYG--NDWYGYFMRRLAERPANVAFV 298
Cdd:pfam01619 240 RFEFQQLYGMGDNLSFALVAAGYRVRKYAPVGphEELLAYLVRRLLENTANSSFV 294
PRK11905 PRK11905
bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed
 13-298 3.15e-15

bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed


Pssm-ID: 237018 [Multi-domain]  Cd Length: 1208  Bit Score: 76.06  E-value: 3.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   13 SKNKALTKLAKKYG---LRFGAGR--------FVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIE 81
Cdd:PRK11905  147 GLSAALTRLIARLGepvIRKAVDMamrmmgeqFVTGETIEEALKRARELEARGYRYSYDMLGEAARTAADAERYYRDYER 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   82 AIRAIGKegldsqlslkmTSMGLDISD--------------------EIVMNNM----RRILEAAKENGVFVTIDMEDYT 137
Cdd:PRK11905  227 AIHAIGK-----------AATGRGVYDgpgisvklsalhpryeraqrERVMAELlprlKALALLAKAYDIGLNIDAEEAD 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  138 RCGKTIDIFKQLKSE-----YDNIGTVIQAY----------LY----RTEKDMedlnaynpNLRLVKGAY-----KEPEE 193
Cdd:PRK11905  296 RLELSLDLLEALCSDpdlagWNGIGFVVQAYqkrcpfvidyLIdlarRSGRRL--------MVRLVKGAYwdaeiKRAQV 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  194 VAFPD------KKDVDDNY----KKIIKMHllNGNYTAIASHD----EAIIEytkkLAEehniPRDQFEFQMLYGIrNER 259
Cdd:PRK11905  368 DGLEGfpvftrKVHTDVSYiacaRKLLAAR--DVIYPQFATHNaqtlAAIYE----LAG----GKGDFEFQCLHGM-GEP 436

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 446358913  260 QLELV----KEGYKMRVYVPYGN--DWYGYFMRRLAERPANVAFV 298
Cdd:PRK11905  437 LYDQVvgkeKLGRPCRIYAPVGTheTLLAYLVRRLLENGANSSFV 481
 
Name Accession Description Interval E-value
PutA COG0506
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 27-277 8.22e-97

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 306.20  E-value: 8.22e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  27 LRFGAGRFVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGKEGLD-SQLSLKMTSMGLD 105
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 106 ISD-------EIVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDMED 173
Cdd:COG0506  189 YSPaqrervvEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDR 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 174 LNA------YNPNLRLVKGAYKEPEEV----------AFPDKKDVDDNYKKIIKMHLLNGN--YTAIASHDEAIIEYTKK 235
Cdd:COG0506  269 LAAlarrggRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446358913 236 LAEEHNIPRDQFEFQMLYGIRNERQLELVKE-GYKMRVYVPYG 277
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVV 391
Pro_dh pfam01619
Proline dehydrogenase;
43-298 4.24e-55

Proline dehydrogenase;


Pssm-ID: 426348 [Multi-domain]  Cd Length: 296  Bit Score: 180.77  E-value: 4.24e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   43 ATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGKE------GLDSQLSLKMTSMG--LDISD-----E 109
Cdd:pfam01619   1 ALKTIEKLRKQGYRFSLDMLGEAALTEADADRYLDAYLRAIDALGKAagpwplGPRPGISVKLSALHprYEPLErervmA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  110 IVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDMEDLNA------YN 178
Cdd:pfam01619  81 ELLERLRPLCRLAKELGVRLNIDAEEADRLDLTLDLFERLLAEpelrgWNGVGITLQAYLKDALAVLDWLLElarrrgRP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  179 PNLRLVKGAY--KEPEEVA--------FPDKKDVDDNYKKIIKMhLLNGN---YTAIASHDEAIIEYTKKLAEEHNIPRD 245
Cdd:pfam01619 161 LGVRLVKGAYwdSEIKRAQqggwpypvFTRKEATDANYEACARF-LLENHdriYPQFATHNARSVAAALALAEELGIPPR 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446358913  246 QFEFQMLYGIRNERQLELVKEGYKMRVYVPYG--NDWYGYFMRRLAERPANVAFV 298
Cdd:pfam01619 240 RFEFQQLYGMGDNLSFALVAAGYRVRKYAPVGphEELLAYLVRRLLENTANSSFV 294
PRK11905 PRK11905
bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed
 13-298 3.15e-15

bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed


Pssm-ID: 237018 [Multi-domain]  Cd Length: 1208  Bit Score: 76.06  E-value: 3.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   13 SKNKALTKLAKKYG---LRFGAGR--------FVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIE 81
Cdd:PRK11905  147 GLSAALTRLIARLGepvIRKAVDMamrmmgeqFVTGETIEEALKRARELEARGYRYSYDMLGEAARTAADAERYYRDYER 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   82 AIRAIGKegldsqlslkmTSMGLDISD--------------------EIVMNNM----RRILEAAKENGVFVTIDMEDYT 137
Cdd:PRK11905  227 AIHAIGK-----------AATGRGVYDgpgisvklsalhpryeraqrERVMAELlprlKALALLAKAYDIGLNIDAEEAD 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  138 RCGKTIDIFKQLKSE-----YDNIGTVIQAY----------LY----RTEKDMedlnaynpNLRLVKGAY-----KEPEE 193
Cdd:PRK11905  296 RLELSLDLLEALCSDpdlagWNGIGFVVQAYqkrcpfvidyLIdlarRSGRRL--------MVRLVKGAYwdaeiKRAQV 367

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  194 VAFPD------KKDVDDNY----KKIIKMHllNGNYTAIASHD----EAIIEytkkLAEehniPRDQFEFQMLYGIrNER 259
Cdd:PRK11905  368 DGLEGfpvftrKVHTDVSYiacaRKLLAAR--DVIYPQFATHNaqtlAAIYE----LAG----GKGDFEFQCLHGM-GEP 436

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*
gi 446358913  260 QLELV----KEGYKMRVYVPYGN--DWYGYFMRRLAERPANVAFV 298
Cdd:PRK11905  437 LYDQVvgkeKLGRPCRIYAPVGTheTLLAYLVRRLLENGANSSFV 481
PRK11904 PRK11904
bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;
17-298 7.36e-15

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;


Pssm-ID: 237017 [Multi-domain]  Cd Length: 1038  Bit Score: 74.85  E-value: 7.36e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   17 ALTKLAKKYG---LRFGAGR--------FVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRA 85
Cdd:PRK11904  152 VLKRLVNRLGepvIRKAMRQamkimgkqFVLGRTIEEALKRARSARNKGYRYSFDMLGEAALTAADAERYFKAYARAIEA 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   86 IGKEGLDSQL------SLKMTSmgLD-----ISDEIVMNNM----RRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLK 150
Cdd:PRK11904  232 IGRAAGGADLparpgiSIKLSA--LHpryeaAQRERVLAELvprvLELARLAKEANIGLTIDAEEADRLELSLDLFEALF 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  151 SE-----YDNIGTVIQAY-------------LYRTEKD--MedlnaynpnLRLVKGAY-----KEPEEVAFPD------K 199
Cdd:PRK11904  310 RDpslkgWGGFGLAVQAYqkralpvldwladLARRQGRriP---------VRLVKGAYwdseiKRAQELGLPGypvftrK 380

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  200 KDVDDNY----KKIIKM--HLlngnYTAIASHD----EAIIEytkkLAEEHNiprdqFEFQMLYGIRNErqL-ELVKEGY 268
Cdd:PRK11904  381 AATDVSYlacaRKLLSArgAI----YPQFATHNahtvAAILE----MAGHRG-----FEFQRLHGMGEA--LyDALLDAP 445

                         330       340       350
                  ....*....|....*....|....*....|....
gi 446358913  269 KM--RVYVPYG--NDWYGYFMRRLAERPANVAFV 298
Cdd:PRK11904  446 GIpcRIYAPVGshKDLLPYLVRRLLENGANSSFV 479
putA PRK11809
trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate ...
 16-298 1.95e-08

trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed


Pssm-ID: 236989 [Multi-domain]  Cd Length: 1318  Bit Score: 55.36  E-value: 1.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   16 KALTKLAKKYG---LRFG---AGR-----FVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEAnEMANQSIE-AI 83
Cdd:PRK11809  230 SSLNRIIGKSGeplIRKGvdmAMRlmgeqFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTEADA-QAYLASYEqAI 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913   84 RAIGK--------EGldSQLSLKMTSMGLDISD---EIVMNNM----RRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQ 148
Cdd:PRK11809  309 HAIGKasngrgiyEG--PGISIKLSALHPRYSRaqyDRVMEELyprlKSLTLLARQYDIGINIDAEEADRLEISLDLLEK 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  149 LKSE-----YDNIGTVIQAYLYRTEK------DMEDLNAYNPNLRLVKGAYKEPE----EV-------AFPDKKDVDDNY 206
Cdd:PRK11809  387 LCFEpelagWNGIGFVIQAYQKRCPFvidyliDLARRSRRRLMIRLVKGAYWDSEikraQVdglegypVYTRKVYTDVSY 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  207 ----KKiikmhLL---NGNYTAIASHDEAIIEYTKKLAEEHNIPrDQFEFQMLYGIrNERQLELV-------KEGYKMRV 272
Cdd:PRK11809  467 lacaRK-----LLavpNLIYPQFATHNAHTLAAIYHLAGQNYYP-GQYEFQCLHGM-GEPLYEQVvgkvadgKLNRPCRI 539

                         330       340
                  ....*....|....*....|....*...
gi 446358913  273 YVPYGN--DWYGYFMRRLAERPANVAFV 298
Cdd:PRK11809  540 YAPVGTheTLLAYLVRRLLENGANTSFV 567
PLN02681 PLN02681
proline dehydrogenase
 34-291 4.24e-08

proline dehydrogenase


Pssm-ID: 215366 [Multi-domain]  Cd Length: 455  Bit Score: 53.94  E-value: 4.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913  34 FVAGETIELATAAIKQLNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIR-AIGKEGLDSQLSLKMTSMG--------- 103
Cdd:PLN02681  88 FCAGEDAEEAARTVRRLWELGLGGILDYAAEDAGDNAACDRNLEKFLAAIRaAATLPPSSSSAAVKITALCppsllervs 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 104 ---------------------------------------LDISDEIVMNNM----RRILEAAKENGVFVTIDMEdYTRCG 140
Cdd:PLN02681 168 dllrwqdrdpngklpwkqwsfplfadssplyhatsepepLTAEEERLLELAherlQKLCERAAQLGVPLLIDAE-YTSLQ 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 141 KTID-IFKQLKSEYDN------IGTVIQAYLyrteKDM-----EDLNA-----YNPNLRLVKGAYKEPE-EVA------- 195
Cdd:PLN02681 247 PAIDyITYDLAREFNKgkdrpiVYGTYQAYL----KDArerlrLDLERseregVPLGAKLVRGAYLSLErRLAaslgvps 322

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358913 196 --FPDKKDVDDNYKK---IIKMHLLNGNYTAI-ASHDEAIIEYTKKLAEEHNIPR--DQFEFQMLYGIRNERQLELVKEG 267
Cdd:PLN02681 323 pvHDTIQDTHACYNRcaeFLLEKASNGDGEVMlATHNVESGELAAAKMNELGLHKgdPRVQFAQLLGMSDNLSFGLGNAG 402

                        330       340
                 ....*....|....*....|....*.
gi 446358913 268 YKMRVYVPYG--NDWYGYFMRRLAER 291
Cdd:PLN02681 403 FRVSKYLPYGpvEEVIPYLLRRAEEN 428
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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