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Conserved domains on  [gi|446358925|ref|WP_000436780|]
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MULTISPECIES: proline dehydrogenase family protein [Bacillus]

Protein Classification

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; proline dehydrogenase family protein; proline dehydrogenase family protein( domain architecture ID 11423475)

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase catalyzes the two-step oxidation of proline to glutamate; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase catalyzes the two-step oxidation of proline to glutamate; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate; proline dehydrogenase family protein similar to Pectobacterium carotovorum carbapenem antibiotics biosynthesis protein CarD; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate; proline dehydrogenase family protein similar to human mitochondrial proline dehydrogenase 1 that converts proline to delta-1-pyrroline-5-carboxylate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PutA super family cl33919
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 27-277 2.54e-96

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


The actual alignment was detected with superfamily member COG0506:

Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 304.66  E-value: 2.54e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  27 LRFGAGRFVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGREGLD-SQLSLKMTSMGLD 105
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 106 ISD-------EIVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDIED 173
Cdd:COG0506  189 YSPaqrervvEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDR 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 174 LNA------YNPNLRLVKGAYKEPEEV----------AFPDKKDVDDNYKKIIKMHLLNGN--YTAIASHDEAIIEYTKK 235
Cdd:COG0506  269 LAAlarrggRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446358925 236 LAEEHNIPRDQFEFQMLYGIRNERQLELVKE-GYKMRVYVPYG 277
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVV 391
 
Name Accession Description Interval E-value
PutA COG0506
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 27-277 2.54e-96

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 304.66  E-value: 2.54e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  27 LRFGAGRFVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGREGLD-SQLSLKMTSMGLD 105
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 106 ISD-------EIVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDIED 173
Cdd:COG0506  189 YSPaqrervvEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDR 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 174 LNA------YNPNLRLVKGAYKEPEEV----------AFPDKKDVDDNYKKIIKMHLLNGN--YTAIASHDEAIIEYTKK 235
Cdd:COG0506  269 LAAlarrggRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446358925 236 LAEEHNIPRDQFEFQMLYGIRNERQLELVKE-GYKMRVYVPYG 277
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVV 391
Pro_dh pfam01619
Proline dehydrogenase;
43-298 1.91e-55

Proline dehydrogenase;


Pssm-ID: 426348 [Multi-domain]  Cd Length: 296  Bit Score: 181.54  E-value: 1.91e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   43 ATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGRE------GLDSQLSLKMTSMG--LDISD-----E 109
Cdd:pfam01619   1 ALKTIEKLRKQGYRFSLDMLGEAALTEADADRYLDAYLRAIDALGKAagpwplGPRPGISVKLSALHprYEPLErervmA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  110 IVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDIEDLNA------YN 178
Cdd:pfam01619  81 ELLERLRPLCRLAKELGVRLNIDAEEADRLDLTLDLFERLLAEpelrgWNGVGITLQAYLKDALAVLDWLLElarrrgRP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  179 PNLRLVKGAY--KEPEEVA--------FPDKKDVDDNYKKIIKMhLLNGN---YTAIASHDEAIIEYTKKLAEEHNIPRD 245
Cdd:pfam01619 161 LGVRLVKGAYwdSEIKRAQqggwpypvFTRKEATDANYEACARF-LLENHdriYPQFATHNARSVAAALALAEELGIPPR 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446358925  246 QFEFQMLYGIRNERQLELVKEGYKMRVYVPYG--NDWYGYFMRRLAERPANVAFV 298
Cdd:pfam01619 240 RFEFQQLYGMGDNLSFALVAAGYRVRKYAPVGphEELLAYLVRRLLENTANSSFV 294
PRK11904 PRK11904
bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;
17-298 1.53e-15

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;


Pssm-ID: 237017 [Multi-domain]  Cd Length: 1038  Bit Score: 77.16  E-value: 1.53e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   17 ALTKLAKKYG---LRFGAGR--------FVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRA 85
Cdd:PRK11904  152 VLKRLVNRLGepvIRKAMRQamkimgkqFVLGRTIEEALKRARSARNKGYRYSFDMLGEAALTAADAERYFKAYARAIEA 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   86 IGREGLDSQL------SLKMTSmgLD-----ISDEIVMNNM----RRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLK 150
Cdd:PRK11904  232 IGRAAGGADLparpgiSIKLSA--LHpryeaAQRERVLAELvprvLELARLAKEANIGLTIDAEEADRLELSLDLFEALF 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  151 SE-----YDNIGTVIQAYLYRTEKDIEDLNA----YN---PnLRLVKGAY-----KEPEEVAFPD------KKDVDDNY- 206
Cdd:PRK11904  310 RDpslkgWGGFGLAVQAYQKRALPVLDWLADlarrQGrriP-VRLVKGAYwdseiKRAQELGLPGypvftrKAATDVSYl 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  207 ---KKIIKM--HLlngnYTAIASHD----EAIIEytkkLAEEHNiprdqFEFQMLYGIRNErqL-ELVKEGYKM--RVYV 274
Cdd:PRK11904  389 acaRKLLSArgAI----YPQFATHNahtvAAILE----MAGHRG-----FEFQRLHGMGEA--LyDALLDAPGIpcRIYA 453

                         330       340
                  ....*....|....*....|....*.
gi 446358925  275 PYG--NDWYGYFMRRLAERPANVAFV 298
Cdd:PRK11904  454 PVGshKDLLPYLVRRLLENGANSSFV 479
 
Name Accession Description Interval E-value
PutA COG0506
Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of ...
 27-277 2.54e-96

Proline dehydrogenase [Amino acid transport and metabolism]; Proline dehydrogenase is part of the Pathway/BioSystem: Proline degradation


Pssm-ID: 440272 [Multi-domain]  Cd Length: 975  Bit Score: 304.66  E-value: 2.54e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  27 LRFGAGRFVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGREGLD-SQLSLKMTSMGLD 105
Cdd:COG0506  109 MRRMARRFVAGETIEEALKAARKLRAKGYRVSLDLLGEAVLTEAEAERYLDAYLEALEAIGAAGVDrPGVSVKLSALGPR 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 106 ISD-------EIVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDIED 173
Cdd:COG0506  189 YSPaqrervvEELLERLRPLARAAREAGIFVTIDMEEYDRLDLTLDVFERLLADpelagWPGVGIVLQAYLKRAEADLDR 268

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 174 LNA------YNPNLRLVKGAYKEPEEV----------AFPDKKDVDDNYKKIIKMHLLNGN--YTAIASHDEAIIEYTKK 235
Cdd:COG0506  269 LAAlarrggRRIRVRLVKGAYWDPEIVraqvhgwpypVFTRKADTDANYLRCARKLLEAGDaiYPQFATHNARTIAAALA 348

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 446358925 236 LAEEHNIPRDQFEFQMLYGIRNERQLELVKE-GYKMRVYVPYG 277
Cdd:COG0506  349 LAGERGRPPDRFEFQMLYGMGEDLQRALAAVdGGRLLLYCPVV 391
Pro_dh pfam01619
Proline dehydrogenase;
43-298 1.91e-55

Proline dehydrogenase;


Pssm-ID: 426348 [Multi-domain]  Cd Length: 296  Bit Score: 181.54  E-value: 1.91e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   43 ATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGRE------GLDSQLSLKMTSMG--LDISD-----E 109
Cdd:pfam01619   1 ALKTIEKLRKQGYRFSLDMLGEAALTEADADRYLDAYLRAIDALGKAagpwplGPRPGISVKLSALHprYEPLErervmA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  110 IVMNNMRRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDIEDLNA------YN 178
Cdd:pfam01619  81 ELLERLRPLCRLAKELGVRLNIDAEEADRLDLTLDLFERLLAEpelrgWNGVGITLQAYLKDALAVLDWLLElarrrgRP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  179 PNLRLVKGAY--KEPEEVA--------FPDKKDVDDNYKKIIKMhLLNGN---YTAIASHDEAIIEYTKKLAEEHNIPRD 245
Cdd:pfam01619 161 LGVRLVKGAYwdSEIKRAQqggwpypvFTRKEATDANYEACARF-LLENHdriYPQFATHNARSVAAALALAEELGIPPR 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446358925  246 QFEFQMLYGIRNERQLELVKEGYKMRVYVPYG--NDWYGYFMRRLAERPANVAFV 298
Cdd:pfam01619 240 RFEFQQLYGMGDNLSFALVAAGYRVRKYAPVGphEELLAYLVRRLLENTANSSFV 294
PRK11904 PRK11904
bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;
17-298 1.53e-15

bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA;


Pssm-ID: 237017 [Multi-domain]  Cd Length: 1038  Bit Score: 77.16  E-value: 1.53e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   17 ALTKLAKKYG---LRFGAGR--------FVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRA 85
Cdd:PRK11904  152 VLKRLVNRLGepvIRKAMRQamkimgkqFVLGRTIEEALKRARSARNKGYRYSFDMLGEAALTAADAERYFKAYARAIEA 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   86 IGREGLDSQL------SLKMTSmgLD-----ISDEIVMNNM----RRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQLK 150
Cdd:PRK11904  232 IGRAAGGADLparpgiSIKLSA--LHpryeaAQRERVLAELvprvLELARLAKEANIGLTIDAEEADRLELSLDLFEALF 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  151 SE-----YDNIGTVIQAYLYRTEKDIEDLNA----YN---PnLRLVKGAY-----KEPEEVAFPD------KKDVDDNY- 206
Cdd:PRK11904  310 RDpslkgWGGFGLAVQAYQKRALPVLDWLADlarrQGrriP-VRLVKGAYwdseiKRAQELGLPGypvftrKAATDVSYl 388

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  207 ---KKIIKM--HLlngnYTAIASHD----EAIIEytkkLAEEHNiprdqFEFQMLYGIRNErqL-ELVKEGYKM--RVYV 274
Cdd:PRK11904  389 acaRKLLSArgAI----YPQFATHNahtvAAILE----MAGHRG-----FEFQRLHGMGEA--LyDALLDAPGIpcRIYA 453

                         330       340
                  ....*....|....*....|....*.
gi 446358925  275 PYG--NDWYGYFMRRLAERPANVAFV 298
Cdd:PRK11904  454 PVGshKDLLPYLVRRLLENGANSSFV 479
PRK11905 PRK11905
bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed
 13-298 1.81e-14

bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed


Pssm-ID: 237018 [Multi-domain]  Cd Length: 1208  Bit Score: 73.75  E-value: 1.81e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   13 SKNKALTKLAKKYG---LRFGAGR--------FVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIE 81
Cdd:PRK11905  147 GLSAALTRLIARLGepvIRKAVDMamrmmgeqFVTGETIEEALKRARELEARGYRYSYDMLGEAARTAADAERYYRDYER 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   82 AIRAIGRegldsqlslkmTSMGLDISD--------------------EIVMNNM----RRILEAAKENGVFVTIDMEDYT 137
Cdd:PRK11905  227 AIHAIGK-----------AATGRGVYDgpgisvklsalhpryeraqrERVMAELlprlKALALLAKAYDIGLNIDAEEAD 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  138 RCGKTIDIFKQLKSE-----YDNIGTVIQAYLYRTEKDIE---DL-NAYNPNL--RLVKGAY-----KEPEEVAFPD--- 198
Cdd:PRK11905  296 RLELSLDLLEALCSDpdlagWNGIGFVVQAYQKRCPFVIDyliDLaRRSGRRLmvRLVKGAYwdaeiKRAQVDGLEGfpv 375

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  199 ---KKDVDDNY----KKIIKMHllNGNYTAIASHD----EAIIEytkkLAEehniPRDQFEFQMLYGIrNERQLELV--- 264
Cdd:PRK11905  376 ftrKVHTDVSYiacaRKLLAAR--DVIYPQFATHNaqtlAAIYE----LAG----GKGDFEFQCLHGM-GEPLYDQVvgk 444

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 446358925  265 -KEGYKMRVYVPYGN--DWYGYFMRRLAERPANVAFV 298
Cdd:PRK11905  445 eKLGRPCRIYAPVGTheTLLAYLVRRLLENGANSSFV 481
PLN02681 PLN02681
proline dehydrogenase
 34-291 9.20e-09

proline dehydrogenase


Pssm-ID: 215366 [Multi-domain]  Cd Length: 455  Bit Score: 55.86  E-value: 9.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  34 FVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEANEMANQSIEAIRAIGR-EGLDSQLSLKMTSMG--------- 103
Cdd:PLN02681  88 FCAGEDAEEAARTVRRLWELGLGGILDYAAEDAGDNAACDRNLEKFLAAIRAAATlPPSSSSAAVKITALCppsllervs 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 104 ---------------------------------------LDISDEIVMNNM----RRILEAAKENGVFVTIDMEdYTRCG 140
Cdd:PLN02681 168 dllrwqdrdpngklpwkqwsfplfadssplyhatsepepLTAEEERLLELAherlQKLCERAAQLGVPLLIDAE-YTSLQ 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 141 KTID-IFKQLKSEYDN------IGTVIQAYLY----RTEKDIEDLNAYNPNL--RLVKGAYKEPE-EVA---------FP 197
Cdd:PLN02681 247 PAIDyITYDLAREFNKgkdrpiVYGTYQAYLKdareRLRLDLERSEREGVPLgaKLVRGAYLSLErRLAaslgvpspvHD 326

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925 198 DKKDVDDNYKK---IIKMHLLNGNYTAI-ASHDEAIIEYTKKLAEEHNIPR--DQFEFQMLYGIRNERQLELVKEGYKMR 271
Cdd:PLN02681 327 TIQDTHACYNRcaeFLLEKASNGDGEVMlATHNVESGELAAAKMNELGLHKgdPRVQFAQLLGMSDNLSFGLGNAGFRVS 406

                        330       340
                 ....*....|....*....|..
gi 446358925 272 VYVPYG--NDWYGYFMRRLAER 291
Cdd:PLN02681 407 KYLPYGpvEEVIPYLLRRAEEN 428
putA PRK11809
trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate ...
 16-298 2.94e-08

trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed


Pssm-ID: 236989 [Multi-domain]  Cd Length: 1318  Bit Score: 54.98  E-value: 2.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   16 KALTKLAKKYG---LRFG---AGR-----FVAGETIELATAAIQALNKQGLCVTIDYLGEFVDNEAEAnEMANQSIE-AI 83
Cdd:PRK11809  230 SSLNRIIGKSGeplIRKGvdmAMRlmgeqFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTEADA-QAYLASYEqAI 308

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925   84 RAIGR--------EGldSQLSLKMTSMGLDISD---EIVMNNM----RRILEAAKENGVFVTIDMEDYTRCGKTIDIFKQ 148
Cdd:PRK11809  309 HAIGKasngrgiyEG--PGISIKLSALHPRYSRaqyDRVMEELyprlKSLTLLARQYDIGINIDAEEADRLEISLDLLEK 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  149 LKSE-----YDNIGTVIQAYLYRTEKDIE---DLNAYNPN---LRLVKGAYKEPE----EV-------AFPDKKDVDDNY 206
Cdd:PRK11809  387 LCFEpelagWNGIGFVIQAYQKRCPFVIDyliDLARRSRRrlmIRLVKGAYWDSEikraQVdglegypVYTRKVYTDVSY 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446358925  207 ----KKiikmhLL---NGNYTAIASHDEAIIEYTKKLAEEHNIPrDQFEFQMLYGIrNERQLELV-------KEGYKMRV 272
Cdd:PRK11809  467 lacaRK-----LLavpNLIYPQFATHNAHTLAAIYHLAGQNYYP-GQYEFQCLHGM-GEPLYEQVvgkvadgKLNRPCRI 539

                         330       340
                  ....*....|....*....|....*...
gi 446358925  273 YVPYGN--DWYGYFMRRLAERPANVAFV 298
Cdd:PRK11809  540 YAPVGTheTLLAYLVRRLLENGANTSFV 567
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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