|
Name |
Accession |
Description |
Interval |
E-value |
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
7-525 |
5.00e-140 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 414.94 E-value: 5.00e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 7 QAFWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQQEAEE 86
Cdd:COG5841 4 QSFLKGALILTAAGLISKILGAIYRIPLQNIIGDEGFGLYQMAYPIYGLFLTLATAGIPVAISKLVAEYNALGDYKGARR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 87 IICVSFWFLLGIGFVGFFTLFFGAETIAAA-MGDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTI 165
Cdd:COG5841 84 IFRVSLLLLLILGLVFFLLLFFGAPFIARLlLGDPRAYYSLRALAPALLIVPVMSVLRGYFQGLQNMTPTAVSQVIEQIV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 166 RVSIIVFLSLFLIARGfdLYTVGAGAMLGSIAGGLIGIIVLVLYMRHDFRSIFFKSVKRIKGKKR----IIKILFWQGLA 241
Cdd:COG5841 164 RVIFILLLAYLLLPYG--LEYAAAGATFGAVIGALAGLLVLLYYYRKRKKKLKRLLEKSKTKSKEsskdILKELLRIAIP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 242 ICVSNLVLIFIQMADSISFYSLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSFIRE 320
Cdd:COG5841 242 ITLSSLVLPLFQLIDSFTVPRRLQAAGLSASEATSLYGILSgMAQPLVNLPTVLATALATSLVPAISEAFAKKDRKLVRR 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 321 KVKLAMKITFVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCL 400
Cdd:COG5841 322 RINQALRLTLLIGLPAAVGLAVLAEPINTLLFGNPEGGGILAILAPSAIFLSLQQVTTGILQGLGKQKIPVINLLIGLLV 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 401 KLVLNYTLMPYFGVKGAAIATLVALIVISVLNSALLMQAVSESLIDKRNMLGVVISGIGMGFVLIIFIRLMQMsglvIDT 480
Cdd:COG5841 402 KIILNYLLVPLFGIYGAALATVIGYLVAAILNLAALKKYTGFKLDLRRRLLKPLLASLIMGIVVLLLYRLLSL----FLP 477
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 446366295 481 RHRGIATLEALLGVAIGGLTYVFLILKLRVFTKAEIGTVMKKEKK 525
Cdd:COG5841 478 ESRLGALLATLIAVLVGAIVYLLLLLKLGLITKEELRRLPKGGKK 522
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
14-432 |
1.15e-130 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 387.21 E-value: 1.15e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 14 IILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQQEAEEIICVSFW 93
Cdd:cd13124 1 LILTIAGLISKILGAIYRIPLQNIIGDEGMGLYQMAYPIYGIFLTLATAGIPVAISKLVAEYNALGDYKGARRIFRVSLI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 94 FLLGIGFVGFFTLFFGAETIAAA-MGDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVSIIVF 172
Cdd:cd13124 81 LLLILGLVFFLLLFFGAPFLAQLlLGDPRLAPVIRALAPAILIVPLLSVLRGYFQGLQNMTPTAVSQVIEQIVRVIVILV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 173 LSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLVLYM---RHDFRSIFFKSVKRIKGKKRIIKILFWQGLAICVSNLVL 249
Cdd:cd13124 161 LAYLLLPVGGGLYYAAAGATFGAVIGALAGLLVLLYYYrkkRRELKRLLRKSPRSKISTKEILKELLSYAIPITLSSLIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 250 IFIQMADSISFYSLLIGAGEQAESAKVLKGVY-DRSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSFIREKVKLAMKI 328
Cdd:cd13124 241 PLLQLIDSFTVPRRLQAAGLSESEATALYGILtGRAQPLVQLPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 329 TFVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCLKLVLNYTL 408
Cdd:cd13124 321 TLLIGLPAAVGLAVLAEPINTLLFGDSEGGLILQILAPSILFLSLQQVTAAILQGLGKVKIPVINLLIGLLVKIVLNYVL 400
|
410 420
....*....|....*....|....
gi 446366295 409 MPYFGVKGAAIATLVALIVISVLN 432
Cdd:cd13124 401 IPIFGIYGAAIATVIGFLVAALLN 424
|
|
| spore_V_B |
TIGR02900 |
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial ... |
9-504 |
1.29e-39 |
|
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial endopore formation program in Bacillus subtilis and various other Firmcutes. It is nearly universal among endospore-formers. Paralogs with rather high sequence similarity to SpoVB exist, including YkvU in B. subtilis and a number of proteins in the genus Clostridium. [Cellular processes, Sporulation and germination]
Pssm-ID: 274343 [Multi-domain] Cd Length: 488 Bit Score: 150.52 E-value: 1.29e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 9 FWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQQEAEEII 88
Cdd:TIGR02900 1 FLKGTFILTIANLITRILGFIFRIVLSRILGAEGVGLYGMAMPIYFLFITLTTGGLPVAISKFVAEASAKNDRKNIKKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 89 CVSFWFLLGIGFVGFFTLFFGAETIAAAM-GDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:TIGR02900 81 KVSLIFTLIWSLIVTAIVFLLSPFIASTLlKDERSLYSLLVICPAMPFIALSSVLKGYFQGISNMKPPAYIQVIEQIVRI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 168 SI-IVFLSLFLIARgfdLYTVGAGAMLGSIAGGLIGIIVLV-LYMRHDFRSIFFKSVKRIKGKKRIIKILFWQGLAICVS 245
Cdd:TIGR02900 161 SVvALLISAFLPYG---LEYAVAGAYLSLVLGELVSLLYLYfFFKRKKSFSIRFPFFDYKSEGKALLFDLFSVSLPLTLS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 246 NLVLIFIQMADSISFYSLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSFIREKVKL 324
Cdd:TIGR02900 238 RFIGSLLYFLETLLVPQRLVIAGVTYREATSLYGKLSgMAMPLLTFPAVITSSLSTALVPDISEAMAKKNYSSIEKRINQ 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 325 AMKITFVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCLKLVL 404
Cdd:TIGR02900 318 AIKISLLLGLITTVILLVIPDELGALFYGRPDAGNFIRVLAPSFPFLYFSAPLQSILQGLGKQKVALRNSLIGAIVKIIL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 405 NYTL--MPYFGVKGAAIATLVALIVISVLNSALLMQAVSESlIDKRNMLGVVISGIGMGFVLIIFIRLMQMSGLVIDTrh 482
Cdd:TIGR02900 398 LFVLtsIPSINIYGYAITFIITSVLVTILNLAEIKKNIRIT-IDLSDFLIFALLGILVYLGLSLLKYIIFNPNILINL-- 474
|
490 500
....*....|....*....|..
gi 446366295 483 rgiatleaLLGVAIGGLTYVFL 504
Cdd:TIGR02900 475 --------LLIIILGFSLYILL 488
|
|
| Polysacc_synt |
pfam01943 |
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. ... |
9-307 |
6.83e-20 |
|
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis, which is involved in spore cortex biosynthesis.
Pssm-ID: 426523 [Multi-domain] Cd Length: 274 Bit Score: 89.67 E-value: 6.83e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 9 FWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAErlERGKQQEAEeii 88
Cdd:pfam01943 1 LLKNVIVLLLSQLITYLLAFVTLPYLARILGPEGFGLYAFALAFVGLLTIFTDFGFNAALVREIAK--YREKYELVS--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 89 cvSFWFLLGIGFVGFFTLFFGAETIAAAMGDIHLDKLLRVISFSFILMPF-LSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:pfam01943 76 --LYWLNALLVKLVLVLLFLLLPLIAAFLGLPELAVLYRILALMFLLLPGvVQFRRGLFQGLERMKYALISQIVESLSRV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 168 SiivfLSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLVLYMRHDFRSIFFKSVkrikgkkriiKILFWQGLAICVSNL 247
Cdd:pfam01943 154 I----LVFIAVFLPGDIVAALLYQVLAALVGGIIALAVLRKIFRPRFVFPSLKLV----------RKLLSFGAPLFISSL 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446366295 248 VLIFIQMADSIsFYSLLIGAGEqaesakvlKGVYDRSIPLMQLGT-VVTTSFSLSLIPIIT 307
Cdd:pfam01943 220 AISLYTYIDSI-LLGLLLGAGA--------VGIYNAAYQLLVAIQgLLNPIVTAVLFPVFS 271
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoVB |
COG5841 |
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle ... |
7-525 |
5.00e-140 |
|
Stage V sporulation protein SpoVB/SpoIIIF, required for spore cortex synthesis [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444543 [Multi-domain] Cd Length: 532 Bit Score: 414.94 E-value: 5.00e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 7 QAFWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQQEAEE 86
Cdd:COG5841 4 QSFLKGALILTAAGLISKILGAIYRIPLQNIIGDEGFGLYQMAYPIYGLFLTLATAGIPVAISKLVAEYNALGDYKGARR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 87 IICVSFWFLLGIGFVGFFTLFFGAETIAAA-MGDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTI 165
Cdd:COG5841 84 IFRVSLLLLLILGLVFFLLLFFGAPFIARLlLGDPRAYYSLRALAPALLIVPVMSVLRGYFQGLQNMTPTAVSQVIEQIV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 166 RVSIIVFLSLFLIARGfdLYTVGAGAMLGSIAGGLIGIIVLVLYMRHDFRSIFFKSVKRIKGKKR----IIKILFWQGLA 241
Cdd:COG5841 164 RVIFILLLAYLLLPYG--LEYAAAGATFGAVIGALAGLLVLLYYYRKRKKKLKRLLEKSKTKSKEsskdILKELLRIAIP 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 242 ICVSNLVLIFIQMADSISFYSLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSFIRE 320
Cdd:COG5841 242 ITLSSLVLPLFQLIDSFTVPRRLQAAGLSASEATSLYGILSgMAQPLVNLPTVLATALATSLVPAISEAFAKKDRKLVRR 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 321 KVKLAMKITFVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCL 400
Cdd:COG5841 322 RINQALRLTLLIGLPAAVGLAVLAEPINTLLFGNPEGGGILAILAPSAIFLSLQQVTTGILQGLGKQKIPVINLLIGLLV 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 401 KLVLNYTLMPYFGVKGAAIATLVALIVISVLNSALLMQAVSESLIDKRNMLGVVISGIGMGFVLIIFIRLMQMsglvIDT 480
Cdd:COG5841 402 KIILNYLLVPLFGIYGAALATVIGYLVAAILNLAALKKYTGFKLDLRRRLLKPLLASLIMGIVVLLLYRLLSL----FLP 477
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 446366295 481 RHRGIATLEALLGVAIGGLTYVFLILKLRVFTKAEIGTVMKKEKK 525
Cdd:COG5841 478 ESRLGALLATLIAVLVGAIVYLLLLLKLGLITKEELRRLPKGGKK 522
|
|
| MATE_SpoVB_like |
cd13124 |
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related ... |
14-432 |
1.15e-130 |
|
Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240529 [Multi-domain] Cd Length: 434 Bit Score: 387.21 E-value: 1.15e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 14 IILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQQEAEEIICVSFW 93
Cdd:cd13124 1 LILTIAGLISKILGAIYRIPLQNIIGDEGMGLYQMAYPIYGIFLTLATAGIPVAISKLVAEYNALGDYKGARRIFRVSLI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 94 FLLGIGFVGFFTLFFGAETIAAA-MGDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVSIIVF 172
Cdd:cd13124 81 LLLILGLVFFLLLFFGAPFLAQLlLGDPRLAPVIRALAPAILIVPLLSVLRGYFQGLQNMTPTAVSQVIEQIVRVIVILV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 173 LSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLVLYM---RHDFRSIFFKSVKRIKGKKRIIKILFWQGLAICVSNLVL 249
Cdd:cd13124 161 LAYLLLPVGGGLYYAAAGATFGAVIGALAGLLVLLYYYrkkRRELKRLLRKSPRSKISTKEILKELLSYAIPITLSSLIL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 250 IFIQMADSISFYSLLIGAGEQAESAKVLKGVY-DRSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSFIREKVKLAMKI 328
Cdd:cd13124 241 PLLQLIDSFTVPRRLQAAGLSESEATALYGILtGRAQPLVQLPTVIATALSTSLVPAISEAYAKGDKKELRRRINQALRL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 329 TFVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCLKLVLNYTL 408
Cdd:cd13124 321 TLLIGLPAAVGLAVLAEPINTLLFGDSEGGLILQILAPSILFLSLQQVTAAILQGLGKVKIPVINLLIGLLVKIVLNYVL 400
|
410 420
....*....|....*....|....
gi 446366295 409 MPYFGVKGAAIATLVALIVISVLN 432
Cdd:cd13124 401 IPIFGIYGAAIATVIGFLVAALLN 424
|
|
| spore_V_B |
TIGR02900 |
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial ... |
9-504 |
1.29e-39 |
|
stage V sporulation protein B; SpoVB is the stage V sporulation protein B of the bacterial endopore formation program in Bacillus subtilis and various other Firmcutes. It is nearly universal among endospore-formers. Paralogs with rather high sequence similarity to SpoVB exist, including YkvU in B. subtilis and a number of proteins in the genus Clostridium. [Cellular processes, Sporulation and germination]
Pssm-ID: 274343 [Multi-domain] Cd Length: 488 Bit Score: 150.52 E-value: 1.29e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 9 FWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERGKQQEAEEII 88
Cdd:TIGR02900 1 FLKGTFILTIANLITRILGFIFRIVLSRILGAEGVGLYGMAMPIYFLFITLTTGGLPVAISKFVAEASAKNDRKNIKKIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 89 CVSFWFLLGIGFVGFFTLFFGAETIAAAM-GDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:TIGR02900 81 KVSLIFTLIWSLIVTAIVFLLSPFIASTLlKDERSLYSLLVICPAMPFIALSSVLKGYFQGISNMKPPAYIQVIEQIVRI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 168 SI-IVFLSLFLIARgfdLYTVGAGAMLGSIAGGLIGIIVLV-LYMRHDFRSIFFKSVKRIKGKKRIIKILFWQGLAICVS 245
Cdd:TIGR02900 161 SVvALLISAFLPYG---LEYAVAGAYLSLVLGELVSLLYLYfFFKRKKSFSIRFPFFDYKSEGKALLFDLFSVSLPLTLS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 246 NLVLIFIQMADSISFYSLLIGAGEQAESAKVLKGVYD-RSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSFIREKVKL 324
Cdd:TIGR02900 238 RFIGSLLYFLETLLVPQRLVIAGVTYREATSLYGKLSgMAMPLLTFPAVITSSLSTALVPDISEAMAKKNYSSIEKRINQ 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 325 AMKITFVIGFAAAIGLTCIIQPTNIMLFENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCLKLVL 404
Cdd:TIGR02900 318 AIKISLLLGLITTVILLVIPDELGALFYGRPDAGNFIRVLAPSFPFLYFSAPLQSILQGLGKQKVALRNSLIGAIVKIIL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 405 NYTL--MPYFGVKGAAIATLVALIVISVLNSALLMQAVSESlIDKRNMLGVVISGIGMGFVLIIFIRLMQMSGLVIDTrh 482
Cdd:TIGR02900 398 LFVLtsIPSINIYGYAITFIITSVLVTILNLAEIKKNIRIT-IDLSDFLIFALLGILVYLGLSLLKYIIFNPNILINL-- 474
|
490 500
....*....|....*....|..
gi 446366295 483 rgiatleaLLGVAIGGLTYVFL 504
Cdd:TIGR02900 475 --------LLIIILGFSLYILL 488
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
11-436 |
1.62e-26 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 111.48 E-value: 1.62e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 11 RGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERgkqqEAEEIICV 90
Cdd:cd13128 3 KNSGWLFVGNIISKLLGFLVRVYLARYLGPEGFGILSLALAFVGLFSIFADLGLPTALVREIARYRKE----KIREIIST 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 91 SFWFLLGIGFVGFFTLFFGAETIAAAMGDIHLdkLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVSII 170
Cdd:cd13128 79 SLVLKLILGILALLLLFLFAFLIAFYDPELVL--LLYILALSLPFSALNSLFRGIFQGFEKMKYIVIARIIESVLSLILA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 171 VFLSLFliarGFDLYtvgaGAMLGSIAGGLIGIIVLVLYMRHDFRSIFFKSVKRIKGKKriikiLFWQGLAICVSNLVLI 250
Cdd:cd13128 157 LILVLL----GGGLI----GFALAYLIASVLSAILLLYIYRKKILLPKFFSFDLKLAKE-----LLRFSIPLALSGIFSL 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 251 FIQMADSIsFYSLLIGAGEQaesakvlkGVYDRSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSfIREKVKLAMKITF 330
Cdd:cd13128 224 IYTRIDTI-MLGYFLGDAAV--------GIYNAAYRIAELLLFIPSAISTALFPRISELYKNDKDE-LKKLLKKSFKYLF 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 331 VIGFAAAIGLTCIIQPTNIMLF--ENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCLKLVLNYTL 408
Cdd:cd13128 294 LISLPIAIGLFLFAEPIITLLFgeEYLPAALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLIGALLNVILNLLL 373
|
410 420
....*....|....*....|....*...
gi 446366295 409 MPYFGVKGAAIATLVALIVISVLNSALL 436
Cdd:cd13128 374 IPKYGIIGAAIATLISEFIIFILLLYLL 401
|
|
| Polysacc_synt |
pfam01943 |
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. ... |
9-307 |
6.83e-20 |
|
Polysaccharide biosynthesis protein; Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon. The family includes SpoVB from Bacillus subtilis, which is involved in spore cortex biosynthesis.
Pssm-ID: 426523 [Multi-domain] Cd Length: 274 Bit Score: 89.67 E-value: 6.83e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 9 FWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAErlERGKQQEAEeii 88
Cdd:pfam01943 1 LLKNVIVLLLSQLITYLLAFVTLPYLARILGPEGFGLYAFALAFVGLLTIFTDFGFNAALVREIAK--YREKYELVS--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 89 cvSFWFLLGIGFVGFFTLFFGAETIAAAMGDIHLDKLLRVISFSFILMPF-LSVARGYFQGFNNMMPTAVSQVIEQTIRV 167
Cdd:pfam01943 76 --LYWLNALLVKLVLVLLFLLLPLIAAFLGLPELAVLYRILALMFLLLPGvVQFRRGLFQGLERMKYALISQIVESLSRV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 168 SiivfLSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLVLYMRHDFRSIFFKSVkrikgkkriiKILFWQGLAICVSNL 247
Cdd:pfam01943 154 I----LVFIAVFLPGDIVAALLYQVLAALVGGIIALAVLRKIFRPRFVFPSLKLV----------RKLLSFGAPLFISSL 219
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446366295 248 VLIFIQMADSIsFYSLLIGAGEqaesakvlKGVYDRSIPLMQLGT-VVTTSFSLSLIPIIT 307
Cdd:pfam01943 220 AISLYTYIDSI-LLGLLLGAGA--------VGIYNAAYQLLVAIQgLLNPIVTAVLFPVFS 271
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
9-431 |
2.71e-19 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 89.62 E-value: 2.71e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 9 FWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAERLERgkqqEAEEII 88
Cdd:COG2244 4 LLKNTLWLLLGQLLGALLGFLLLPLLARLLGPEEYGLFALALSIVALLSVLADLGLSTALVRFIAEYREE----ELRRLL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 89 CVSFWFLLGIGFVGFFTLFFGAETIAAAMGDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRVs 168
Cdd:COG2244 80 STALLLRLLLSLLLALLLLLLAPFIAALLGEPELALLLLLLALALLLSALSAVLLALLRGLERFKLLALINILSSLLSL- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 169 iivFLSLFLIARGFDLYTVgagamlgsiaggligiivlvlymrhdfrsiffksvkrikgkkriikiLFWQGLAICVSNLV 248
Cdd:COG2244 159 ---LLALLLALLGLGLWGL-----------------------------------------------VLKYSLPLLLSGLL 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 249 LIFIQMADSIsFYSLLIGAGEQaesakvlkGVYDRSIPLMQLGTVVTTSFSLSLIPIITAAKERGDLSFIREKVKLAMKI 328
Cdd:COG2244 189 GLLLTNLDRL-LLGALLGPAAV--------GIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRL 259
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 329 TFVIGFAAAIGLTCIIQPTNIMLF--ENSDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIFVIFGGCLKLVLNY 406
Cdd:COG2244 260 LLLLGLPLALGLALLAPPLLSLLFgpEYAEAAPVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLNLVLNL 339
|
410 420
....*....|....*....|....*
gi 446366295 407 TLMPYFGVKGAAIATLVALIVISVL 431
Cdd:COG2244 340 LLIPRYGLVGAAIATLLSYLVLLLL 364
|
|
| Polysacc_synt_C |
pfam14667 |
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral ... |
376-510 |
2.30e-13 |
|
Polysaccharide biosynthesis C-terminal domain; This family represents the C-terminal integral membrane region of polysaccharide biosynthesis proteins.
Pssm-ID: 434111 [Multi-domain] Cd Length: 141 Bit Score: 67.21 E-value: 2.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 376 TTASILQGLGQTLKPAIFVIFGGCLKLVLNYTLMPYFGVKGAAIATLVALIVISVLNSALLMQAVSESLIdKRNMLGVVI 455
Cdd:pfam14667 17 VLTSILQGLGRTKLALIALLIGALVKLILNLLLIPLFGIVGAAIATVISLLVVALLNLYYLRRYLGLRLL-LRRLLKPLL 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 446366295 456 SGIGMGFVLIIFIRLMQMSGLVidtrhrgiaTLEALLGVAIGGLTYVFLILKLRV 510
Cdd:pfam14667 96 AALVMGIVVYLLLLLLGLLLGL---------ALALLLAVLVGALVYLLLLLLLKL 141
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
57-427 |
3.74e-11 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 65.04 E-value: 3.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 57 LILATYGFPIIISKMVAERLERGKQQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAMGDIHLD-----KLLRVISF 131
Cdd:cd12082 43 LIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVLAILLGLLLAALLLFFSPLILSLLGAEEEVielaaTYLTILIL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 132 SFILMPFLSVARGYFQGFNNMMPTAVSQVIEQTIRvsiiVFLSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLVLYMR 211
Cdd:cd12082 123 GLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLN----ILLDPLLIFGLGPPELGIAGAALATVISYVIGALLLLIYLR 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 212 HDfRSIFFKSVKRIKGKKRIIKILFWQGLAICVSNLVLIFIQMADsISFYSLLIGAGEQAesakvlkgVYDRSIPLMQLG 291
Cdd:cd12082 199 KG-KKILKFKLSLLKPDLELLRRLLRIGLPSAIQNSLLSLGLLII-VAIVAAFGGAAALA--------AYTVAFRIASLA 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 292 TVVTTSFSLSLIPIITAAKERGDLSFIREKVKLAMKITFVIGfaAAIGLTCIIQPTNIM-LFENSD-----GSDVLSILS 365
Cdd:cd12082 269 FMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIG--AVLGLLILLFPEPILsLFTNDPeflelAVSYLRILA 346
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446366295 366 LSILFSSLSITTASILQGLGQTLKPAIFVIF-GGCLKLVLNYTLMPY-FGVKGAAIATLVALIV 427
Cdd:cd12082 347 IYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLsYWVVRLPLAYVLAYLgLGLYGIWLALVISLIL 410
|
|
| MATE_tuaB_like |
cd13127 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This ... |
80-446 |
9.17e-09 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240532 [Multi-domain] Cd Length: 406 Bit Score: 57.49 E-value: 9.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 80 KQQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAMGDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAVSQ 159
Cdd:cd13127 63 RKDLTEEDLSTVFWLNLLLGLLLYLLLFLLAPLIAAFYNEPELIPLLRVLSLSFLLSGLGSVPRALLQRELRFKKLAIIE 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 160 VIEQTIRVSIIVFLSLFliargfdlytvGAGAM---LGSIAGGLIGIIVLVLYMRHDFRSIFFKSVkrikgkkriIKILF 236
Cdd:cd13127 143 LISTLVSGVVAIVLALL-----------GFGVWalvAQQLVGALVSTVLLWILSRWRPRLSFSLAS---------LKELL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 237 WQGLAICVSNLVLIFIQMADSIsfyslLIGAgeqAESAKVLkGVYDRSIPLMQLG-TVVTTSFSLSLIPIItaAKERGDL 315
Cdd:cd13127 203 SFGSKLLGSNLLNYFSRNLDNL-----IIGK---FLGAAAL-GYYSRAYRLALLPvQNITGPITRVLFPAL--SRLQDDP 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 316 SFIREKVKLAMKITFVIGFAAAIGLTCIIQP-TNIMLFEN-SDGSDVLSILSLSILFSSLSITTASILQGLGQTLKPAIF 393
Cdd:cd13127 272 ERLRRAYLKALRLLALITFPLMVGLALLAEPlVLLLLGEKwLPAVPILQILALAGLFQPLSSLNGSLLLALGRTDLLLKL 351
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 446366295 394 VIFGGCLKLVLnYTLMPYFGVKGAAIATLVALIVISVLNSALLMQAVSESLID 446
Cdd:cd13127 352 GLIKAVLTVLA-LLIGIPYGIIGVAIAYVIASLLSFPLNLYLAGRLIGISLLE 403
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
71-431 |
1.09e-08 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 57.46 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 71 MVAERLERGKQQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAMG---DIHLDKL--LRVISFSFILMPFLSVARGY 145
Cdd:COG0534 70 LVAQALGAGDREEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGadpEVLALARdyLRIILLGLPFLLLFNVLNGI 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 146 FQGFNNMMPTAVSQVIeqtirVSII-VFLSLFLIArGFDLYTVGAGamLGSIAGGLIGIIVLVLYMRHDFRSIFFkSVKR 224
Cdd:COG0534 150 LRGLGDTKTPMIIMLI-----GNVLnIVLDPLLIF-GGGLGVAGAA--LATVISQAVSALLLLYYLFRKRSLLRL-RLRD 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 225 IKGKKRIIKILFWQGLAICVSNLVLIFIQMAdsisFYSLLIGAGEQAESAKVLkgvydrSIPLMQLGTVVTTSFSLSLIP 304
Cdd:COG0534 221 LRPDRKILKRILRIGLPAGLQQLAESLGFLV----LNALVARLGTAAVAAYGI------ALRIESLAFMPALGLGQAAQP 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 305 IITAAKERGDLSFIREKVKLAMKITFVIGFAAAIgLTCIIQPTNIMLFENSD-----GSDVLSILSLSILFSSLSITTAS 379
Cdd:COG0534 291 LVGQNLGAGDYDRARRAARLALLLALGIGLLLAL-LLFLFPEPIIGLFTDDPevialAATYLRIAALFQPFDGLQFVLSG 369
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 446366295 380 ILQGLGQTLKPAIFVIFGGCLKLVLNYTLMPY--FGVKGAAIATLVALIVISVL 431
Cdd:COG0534 370 ALRGAGDTRFPMIISLLRLWLVRLPLAYLLAFlgLGLTGVWLALPIGEVLRALL 423
|
|
| MurJ |
COG0728 |
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
71-510 |
1.50e-06 |
|
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 50.92 E-value: 1.50e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 71 MVAERLERGKQQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAM-GDIHLDKLLRVISFSFILMPFL------SVAR 143
Cdd:COG0728 64 VLAEALEKEGEEEARRFASRVLTLLLLVLLVLTLLGILFAPLLVKLLaPGFDPEKFALAVALTRIMFPYIlfiglsALLG 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 144 GYFQGFNNMMPTAVSQVIeqtIRVSIIVFLSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLV-----LYMRHDFRSIF 218
Cdd:COG0728 144 GVLNARGRFAAPALAPVL---LNLVIIAGLLLLAPLFGPGIYALAWGVLLGGVLQLLIQLPALRrlglrLRPRFDLRDPG 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 219 FKSVkrikgkkriikilFWQGLAICVSNLVLIFIQMADSIsfysLLIGAGEQAESAkvlkgvYDRSIPLMQLGT-VVTTS 297
Cdd:COG0728 221 VRRV-------------LKLMLPALLGVSVSQINLLVDTI----LASFLPEGSVSA------LYYADRLYQLPLgLFGVA 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 298 FSLSLIPIITAAKERGDLSFIREKVKLAMKITFVIGFAAAIGLTCIIQPTNIMLFE--NSDGSDVLSilslsilfsslsi 375
Cdd:COG0728 278 IGTALLPRLSRAAAAGDLEEFRRTLSRGLRLVLLLTLPAAVGLIVLAEPIVRLLFErgAFTAEDTAL------------- 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 376 tTASILQG--------------------LGQTLKPAIFVIFGGCLKLVLNYTLMPYFGVKGAAIATLVAliviSVLNSAL 435
Cdd:COG0728 345 -TALALAAyalglpafalvkvlarafyaRQDTRTPVRIAVIAVVVNIVLNLLLVPPLGHAGLALATSLS----ALVNALL 419
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 436 LMQAVSESLIDK------RNMLGVVISGIGMGFVLIIFIRLmqMSGLVIDTRHRGIATLeaLLGVAIGGLTYVFLILKLR 509
Cdd:COG0728 420 LLVLLRRRLGGLplrgilRTLLKLLLASLVMGAVLWLLLRL--LGDWLGGGLLGRLLAL--ALLILVGAAVYFALLLLLG 495
|
.
gi 446366295 510 V 510
Cdd:COG0728 496 V 496
|
|
| MATE_epsE_like |
cd13129 |
Multidrug and toxic compound extrusion family and similar proteins; This model represents a ... |
9-215 |
1.77e-05 |
|
Multidrug and toxic compound extrusion family and similar proteins; This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins, including Ralstonia solanaceraum GMI1000 epsE, which may be involved in exporting exopolysaccharide EPS I, a virulence factor. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240534 [Multi-domain] Cd Length: 411 Bit Score: 47.10 E-value: 1.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 9 FWRGAIILTIASFVTKVLSAFYRIPYQNIAGDIGFYIYQQIYPFYGFCLILATYGFPIIISKMVAErLERGKQQEAEEII 88
Cdd:cd13129 2 FASGSFWSLGGLVASRGAVFLTNIMVARSLGKHVFGEFGVIQVTIGLLGTFAGFGLGLAATKVIAE-TKDVDPERAGRII 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 89 CVSFWFLLGIGFVGFFTLFFGAETIA-AAMGDIHLDKLLRVISFSFILMPFLSVARGYFQGFNNMMPTAvsqvieqtiRV 167
Cdd:cd13129 81 GLSILLAVVTGALAATVLFLSATWIAiATLNAPHLAELLRIAAIILILTAFTGAQTGFLSGFEAFRAIA---------RV 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446366295 168 SIIVFLSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLVLYMRHDFR 215
Cdd:cd13129 152 NIWAGLLLLPLMWIGVYIRGLVGAVVILLASAAGNVASNSLILRRECQ 199
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
54-212 |
9.59e-05 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 44.76 E-value: 9.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 54 GFCLILATyGFPIIISKMVAERLERGKQQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAMGD----IHL-DKLLRV 128
Cdd:cd13138 271 SFAFLPPS-AIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLIIILLVFFFAPQLLGLFTSdpevIEIgAEYLRI 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 129 ISFSFILMPFLSVARGYFQGFNNMMPTAVSQVIEQ-TIRVSIIVFLSLFLiarGFDLYTVGAGAMLGSIAGGLIGIIVLV 207
Cdd:cd13138 350 YSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLwLVRIPLAYLLSRLT---GLGLFGIWLAMPISNILSAIICIIYYR 426
|
....*
gi 446366295 208 LYMRH 212
Cdd:cd13138 427 KGRWK 431
|
|
| Polysacc_synt_3 |
pfam13440 |
Polysaccharide biosynthesis protein; |
92-340 |
1.83e-04 |
|
Polysaccharide biosynthesis protein;
Pssm-ID: 404342 [Multi-domain] Cd Length: 293 Bit Score: 43.35 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 92 FWFLLGIGFVGFFTLFFGAETIAAAMGDIHLDKLLRVISFSFILMPFLSVARGYFQgfnnmmpTAVSQVIEQTIRVSIIV 171
Cdd:pfam13440 51 FTFNLIFGALIYLILFALAPLIASFYNQPELVPVLRVLALVLILNGLSSVQTALLR-------RDLRFKKLFKITLTSSV 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 172 FLSLFLIARGFDLYTVGAGAmLGSIAGGLigIIVLVLYMRHDFRSIFFKSVkrikgkkRIIKILFWQGLAICVSNLVLIF 251
Cdd:pfam13440 124 IGGIVGIVLAYLGFGVWALV-IGTLAQQL--LSLVLLWLASDWRPRLTFSL-------KVIKELFSFGSWLLLSNLLNYL 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 252 IQMADsisfySLLIGageQAESAKVLkGVYDRSIPLMQL-GTVVTTSFSLSLIPIITAAKErgDLSFIREKVKLAMKITF 330
Cdd:pfam13440 194 ARNLD-----NLIIG---KVLGTAAL-GLYSVAYRLALLpTANITSVITKVLFPALSRIQD--DKAKLRELYLRVLRLIA 262
|
250
....*....|
gi 446366295 331 VIGFAAAIGL 340
Cdd:pfam13440 263 FIVFPIMAGL 272
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
378-431 |
4.11e-04 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 42.83 E-value: 4.11e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 446366295 378 ASILQGLGQTLKPAIFVIFGGCLKLVLNYTLMPYF--GVKGAAIATLVALIVISVL 431
Cdd:cd13138 143 SAILRGLGDSKTPLYFVIIACVLNIILDLLFIAVFhmGVAGAALATVIAQAISVLL 198
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|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
376-437 |
1.57e-03 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 40.96 E-value: 1.57e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446366295 376 TTASILQGLGQTLKPAIFVIFGGCLKLVLNYTLM------PYFGVKGAAIATLVALIVISVLNSALLM 437
Cdd:cd13137 138 VGNAALRGAGDTKTPMYIMIIVNVLNIVLDYVLIfglwgfPGLGVAGAALATVISRVVGALLLLFLLL 205
|
|
| MATE_MurJ_like |
cd13123 |
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
73-436 |
2.28e-03 |
|
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240528 [Multi-domain] Cd Length: 420 Bit Score: 40.51 E-value: 2.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 73 AERLERGKQQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAM-GDIHLDKLLRVISFSFILMPFL------SVARGY 145
Cdd:cd13123 59 SEYLEKEGEEEARRFASRVLTLLLLVLLLLTLLGILFAPLLVKLLaPGFSGDKFELAVALTRIMFPYLlfislsALLGGI 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 146 FQGFNNMMPTAVSQVIeqtIRVSIIVFLSLFLIARGFDLYTVGAGAMLGSIAGGLIGIIVLVLYMRHDFRSIFFKSVKRI 225
Cdd:cd13123 139 LNAHGRFFAPALAPVL---LNLVIIAGLLLLAPLFDLGIYALAWGVLLGGVLQLLVQLPALRRLGFRFRPRLDFRDPGVR 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 226 KGKKRIIKILFwqGLAICVSNLVLifiqmadSISFYSLLIGAGeqaesakvlKGVYDRSIPLMQLGT-VVTTSFSLSLIP 304
Cdd:cd13123 216 RVLKLMLPALL--GVSVSQINLLV-------DTILASFLPEGS---------ISALYYADRLYQLPLgIFGVAIATALLP 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 305 IITAAKERGDLSFIREKVKLAMKITFVIGFAAAIGLTCIIQPTNIMLFE--NSDGSDVLSilslsilfsslsitTASILQ 382
Cdd:cd13123 278 RLSRLAAAGDLDEFRRTLSRGLRLVLFLLLPAAVGLIVLAEPIVRLLFErgAFTAEDTLM--------------TASALA 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446366295 383 G--------------------LGQTLKPAIFVIFGGCLKLVLNYTLMPYFGVKGAAIATLVALIVISVLNSALL 436
Cdd:cd13123 344 AyalglpafalvkllsrafyaLKDTKTPVKIAVIAVAVNILLNLLLIKPLGHVGLALATSLSAWVNALLLLVLL 417
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|
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
72-437 |
3.07e-03 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 40.19 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 72 VAERLERGKQQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAMG-DIHLDKL----LRVISFSFILMPFLSVARGYF 146
Cdd:cd13143 68 ISRRLGAGDREKANRIFSTALLLSLILGLLLTILGLLFLDPLLRLLGaSGELLPYavdyLRIILLGAPFTILSSVLNNLL 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 147 QGFNN----MMPTAVSQVIEqtirvsiIVFLSLFLIARGFDLytvgAGAMLGSIAGGLIGIIVLVLYMRHdFRSIFFKSV 222
Cdd:cd13143 148 RAEGKpklaMLGMLIGAVLN-------IILDPLFIFVLGLGI----AGAALATVIAQLISLLLLLLYFFR-GKSLLKLSL 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 223 KRIKGKKRIIKILFWQGLAICVSNLVLIFIQMadsISFYSLLIGAGEQAESAkvlkgvYDRSIPLMQLGTVVTTSFSLSL 302
Cdd:cd13143 216 LRFKLSLKIIKEILALGFPSFLMQLSSSVVTI---VLNLTLLGYGGDIGVAA------FGIVTRILTFLFLPLIGLSQGL 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 303 IPIITAAKERGDLSFIREKVKLAMKITFVIGFAAAIglTCIIQPTNIMLFENSD------GSDVLSILSLSILFSSLSIT 376
Cdd:cd13143 287 QPIIGYNYGAGNYDRVKQALKLALIVALIYGLVLFL--ILLLFPEQIVSLFTDDpelialAARILRIFLLAFPLAGINIV 364
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446366295 377 TASILQGLGQTLKPAIFVIF-GGCLKLVLNYTLMPYFGVKGAAIATLVALIVISVLNSALLM 437
Cdd:cd13143 365 LSGYFQAIGKAKRAALLSLLrQGLFLIPLLLILPRLFGLDGIWLAFPLAEILTLLLALILLK 426
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
56-211 |
3.35e-03 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 39.97 E-value: 3.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 56 CLILATYGFPIIISKMVAERLErgkqQEAEEIICVSFWFLLGIGFVGFFTLFFGAETIAAAMGD-----IHLDKLLRVIS 130
Cdd:cd13135 52 FLGSISIGFTILGSQSVGAKDI----KRINDYAISSIVYNSIIGVILFLLWLFGARIIFVLFGVdgqilGYSINYVRIFS 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446366295 131 FSFILMPFLSVARGYFQGFNNMMPTavsqVIEQTIRVSIIVFLSLFLIARGFDLYTVG-AGAMLGSIAGGLIGIIVLVLY 209
Cdd:cd13135 128 IYLLLLGILFTFSSILQGIGETKPI----MYGGIIKNLLNVILDYVLIFGNFGFPRLGiIGAAIATTIANVLNLIILVYL 203
|
..
gi 446366295 210 MR 211
Cdd:cd13135 204 CR 205
|
|
| |
