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Conserved domains on  [gi|446369300|ref|WP_000447155|]
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MULTISPECIES: sigma-70 family RNA polymerase sigma factor [Bacillus]

Protein Classification

sigma-70 family RNA polymerase sigma factor( domain architecture ID 11484432)

sigma-70 family RNA polymerase sigma factor is an initiation factor that promotes the attachment of RNA polymerase to specific initiation sites and is then released; similar to Mycobacterium tuberculosis extracytoplasmic function (ECF) RNA polymerase sigma factor SigJ

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
1-289 1.45e-163

RNA polymerase sigma factor SigJ; Provisional


:

Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 455.92  E-value: 1.45e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   1 METEQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQsIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGM 80
Cdd:PRK09636   4 ADAAAEFEPLRPHLLSVAYRMLGSVADAEDIVQEAWLRWNNADRAQ-IRDPRAWLTRVVTRLCLDRLRSARHRRETYVGP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  81 WLPEPLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:PRK09636  83 WLPEPVVEELDDPLEAVVAAEDLSLALMLALERLSPLERAAFLLHDVFGVPFDEIASTLGRSPAACRQLASRARKHVRAA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300 161 PKQSKLSTEKMAAYVEKFVSSLQCGDAEGMLEVLKTDAILKADGGGKVTTAIHPIYSADRIIRLFFGIAQRLTE--EYTV 238
Cdd:PRK09636 163 RPRFPVSDEEGAELVEAFFAALASGDLDALVALLAPDVVLHADGGGKVPTALRPIYGADKVARFFLGLARRYGPggSTLV 242
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446369300 239 DFKMVNGIPGVIVTINNKVTYVLSFAFEDEKISNIYMMVNPEKLMHLNVKI 289
Cdd:PRK09636 243 RLALVNGLPGFVTAEADGEPQTTALEVEDGKIVAIYDVRNPDKLTHLPLKI 293
 
Name Accession Description Interval E-value
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
1-289 1.45e-163

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 455.92  E-value: 1.45e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   1 METEQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQsIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGM 80
Cdd:PRK09636   4 ADAAAEFEPLRPHLLSVAYRMLGSVADAEDIVQEAWLRWNNADRAQ-IRDPRAWLTRVVTRLCLDRLRSARHRRETYVGP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  81 WLPEPLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:PRK09636  83 WLPEPVVEELDDPLEAVVAAEDLSLALMLALERLSPLERAAFLLHDVFGVPFDEIASTLGRSPAACRQLASRARKHVRAA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300 161 PKQSKLSTEKMAAYVEKFVSSLQCGDAEGMLEVLKTDAILKADGGGKVTTAIHPIYSADRIIRLFFGIAQRLTE--EYTV 238
Cdd:PRK09636 163 RPRFPVSDEEGAELVEAFFAALASGDLDALVALLAPDVVLHADGGGKVPTALRPIYGADKVARFFLGLARRYGPggSTLV 242
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446369300 239 DFKMVNGIPGVIVTINNKVTYVLSFAFEDEKISNIYMMVNPEKLMHLNVKI 289
Cdd:PRK09636 243 RLALVNGLPGFVTAEADGEPQTTALEVEDGKIVAIYDVRNPDKLTHLPLKI 293
SigX4 TIGR02957
RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of ...
5-286 2.75e-160

RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.


Pssm-ID: 132002 [Multi-domain]  Cd Length: 281  Bit Score: 447.19  E-value: 2.75e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300    5 QLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIEnIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMWLPE 84
Cdd:TIGR02957   1 EEFEALRPLLFSLAYRMLGSVADAEDIVQETFLRWQEAD-RAQIENPKAYLTKVVTRRCIDVLRSARARREVYVGPWLPE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   85 PLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEKPKQS 164
Cdd:TIGR02957  80 PLLTTSADPAESVELAESLSMAYLLLLERLSPLERAVFVLREVFDYPYEEIASIVGKSEANCRQLVSRARRHLDARRPRF 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  165 KLSTEKMAAYVEKFVSSLQCGDAEGMLEVLKTDAILKADGGGKVTTAIHPIYSADRIIRLFFGIAQRLTEEYTVDFKMVN 244
Cdd:TIGR02957 160 EVSREESRQLLERFVEAAQTGDLDGLLELLAEDVVLYGDGGGKVRAALRPIYGADRVARFFFGLVRRLGPGGRVDPVDVN 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 446369300  245 GIPGVIVTINNKVTYVLSFAFEDEKISNIYMMVNPEKLMHLN 286
Cdd:TIGR02957 240 GQPAVLVRIDGKLAYVVTFAIEGGGIQNIYIVRNPEKLAHIG 281
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
4-160 2.25e-38

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 133.20  E-value: 2.25e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGmwL 82
Cdd:COG1595   20 EELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLwRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRRELLDE--L 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300  83 PEPLVEESDEPSESFVMKEsLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:COG1595   98 AEELPDEAADPEEALEAEE-LLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLSRARKKLREA 174
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
6-71 6.47e-15

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 68.00  E-value: 6.47e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446369300    6 LYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMK--AYLCKMATNRSIDKLRSAA 71
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLwRAIERFDPERGVSfsTWLYTIIRNAIIDYLRKQR 69
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
111-157 9.44e-03

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 33.62  E-value: 9.44e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 446369300 111 LQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSI 157
Cdd:cd06171    8 LDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKL 54
 
Name Accession Description Interval E-value
PRK09636 PRK09636
RNA polymerase sigma factor SigJ; Provisional
1-289 1.45e-163

RNA polymerase sigma factor SigJ; Provisional


Pssm-ID: 236600 [Multi-domain]  Cd Length: 293  Bit Score: 455.92  E-value: 1.45e-163
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   1 METEQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQsIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGM 80
Cdd:PRK09636   4 ADAAAEFEPLRPHLLSVAYRMLGSVADAEDIVQEAWLRWNNADRAQ-IRDPRAWLTRVVTRLCLDRLRSARHRRETYVGP 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  81 WLPEPLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:PRK09636  83 WLPEPVVEELDDPLEAVVAAEDLSLALMLALERLSPLERAAFLLHDVFGVPFDEIASTLGRSPAACRQLASRARKHVRAA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300 161 PKQSKLSTEKMAAYVEKFVSSLQCGDAEGMLEVLKTDAILKADGGGKVTTAIHPIYSADRIIRLFFGIAQRLTE--EYTV 238
Cdd:PRK09636 163 RPRFPVSDEEGAELVEAFFAALASGDLDALVALLAPDVVLHADGGGKVPTALRPIYGADKVARFFLGLARRYGPggSTLV 242
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446369300 239 DFKMVNGIPGVIVTINNKVTYVLSFAFEDEKISNIYMMVNPEKLMHLNVKI 289
Cdd:PRK09636 243 RLALVNGLPGFVTAEADGEPQTTALEVEDGKIVAIYDVRNPDKLTHLPLKI 293
SigX4 TIGR02957
RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of ...
5-286 2.75e-160

RNA polymerase sigma-70 factor, TIGR02957 family; This group of sigma factors are members of the sigma-70 family (TIGR02937). They and appear by homology, tree building and bidirectional best hits, to represent a conserved family. This family is found in a limited number of bacterial lineages. This family includes apparent paralogous expansion in Streptomyces coelicolor A3(2), and multiple copies in Mycobacterium smegmatis MC2, Streptomyces avermitilis MA-4680 and Nocardia farcinica IFM10152.


Pssm-ID: 132002 [Multi-domain]  Cd Length: 281  Bit Score: 447.19  E-value: 2.75e-160
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300    5 QLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIEnIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMWLPE 84
Cdd:TIGR02957   1 EEFEALRPLLFSLAYRMLGSVADAEDIVQETFLRWQEAD-RAQIENPKAYLTKVVTRRCIDVLRSARARREVYVGPWLPE 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   85 PLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEKPKQS 164
Cdd:TIGR02957  80 PLLTTSADPAESVELAESLSMAYLLLLERLSPLERAVFVLREVFDYPYEEIASIVGKSEANCRQLVSRARRHLDARRPRF 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  165 KLSTEKMAAYVEKFVSSLQCGDAEGMLEVLKTDAILKADGGGKVTTAIHPIYSADRIIRLFFGIAQRLTEEYTVDFKMVN 244
Cdd:TIGR02957 160 EVSREESRQLLERFVEAAQTGDLDGLLELLAEDVVLYGDGGGKVRAALRPIYGADRVARFFFGLVRRLGPGGRVDPVDVN 239
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 446369300  245 GIPGVIVTINNKVTYVLSFAFEDEKISNIYMMVNPEKLMHLN 286
Cdd:TIGR02957 240 GQPAVLVRIDGKLAYVVTFAIEGGGIQNIYIVRNPEKLAHIG 281
RpoE COG1595
DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; ...
4-160 2.25e-38

DNA-directed RNA polymerase specialized sigma subunit, sigma24 family [Transcription]; DNA-directed RNA polymerase specialized sigma subunit, sigma24 family is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 441203 [Multi-domain]  Cd Length: 181  Bit Score: 133.20  E-value: 2.25e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGmwL 82
Cdd:COG1595   20 EELYERYRPRLYRYARRLLGDRADAEDLVQETFLRLwRKLDSFRGRGSFRAWLYRIARNLAIDHLRKRRRRRELLDE--L 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300  83 PEPLVEESDEPSESFVMKEsLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:COG1595   98 AEELPDEAADPEEALEAEE-LLEALLAALERLPPRQREVLVLRYLEGLSYAEIAEILGISEGTVKSRLSRARKKLREA 174
sigI PRK09635
RNA polymerase sigma factor SigI; Provisional
7-282 4.04e-33

RNA polymerase sigma factor SigI; Provisional


Pssm-ID: 182008 [Multi-domain]  Cd Length: 290  Bit Score: 122.77  E-value: 4.04e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   7 YEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIEnIQSIENMKAYLCKMATNRSIDKLRSAA--HKRNVYVGMWLPE 84
Cdd:PRK09635  11 WRAHRAYLVDLAFRMVGDIGVAEDMVQEAFSRLLRAP-VGDIDDERGWLIVVTSRLCLDHIKSAStrRERPQDIAAWHDG 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  85 PLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEKPKQS 164
Cdd:PRK09635  90 DASVSSVDPADRVTLDDEVRLALLIMLERLGPAERVVFVLHEIFGLPYQQIATTIGSQASTCRQLAHRARRKINESRIAA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300 165 KLSTEKMAAYVEKFVSSLQCGDAEGMLEVLKTdAILKADGGGKVTTAIHPIYSADRIIRLFFGIAQRLTEEytvdfkMVN 244
Cdd:PRK09635 170 SVEPAQHRVVTRAFIEACSNGDLDTLLEVLDP-GVAGEIDARKGVVVVGADRVGPTILRHWSHPATVLVAQ------PVC 242
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 446369300 245 GIPGVIVTINNKVTYVLSFAFEDEKISNIYMMVNPEKL 282
Cdd:PRK09635 243 GQPAVLAFVNRALAGVLALSIEAGKITKIHVLVQPSTL 280
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
4-160 8.17e-28

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 105.12  E-value: 8.17e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300    4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRsaaHKRNVYVGMWL 82
Cdd:TIGR02937   4 EELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLlEALDRFDPEGSFKAWLFRIARNLILDYLR---RKRRLRRELDL 80
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300   83 PEPLVEESDEPSESFVMKESLSTAYlLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:TIGR02937  81 LEELLDSDPSPEEELEQEEEREALR-EALEKLPEREREVLVLRYLEGLSYKEIAEILGISVGTVKRRLKRARKKLREL 157
PRK08241 PRK08241
RNA polymerase subunit sigma-70;
2-200 1.28e-22

RNA polymerase subunit sigma-70;


Pssm-ID: 236196 [Multi-domain]  Cd Length: 339  Bit Score: 95.39  E-value: 1.28e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   2 ETEQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFI----SLNNIENIQSienMKAYLCKMATNRSIDKLRSAAhKRNVY 77
Cdd:PRK08241  20 AFAALVEPHRRELLAHCYRMLGSVHDAEDAVQETLLrawrGYDRFEGRSS---LRTWLYRIATNVCLDALEGRA-RRPLP 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  78 VGM------------------WLpEP-----LVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEE 134
Cdd:PRK08241  96 TDLgapaadpvdelverpevpWL-EPypdalLDPAAADPAARVVARESVRLAFVAALQHLPPRQRAVLILRDVLGWSAAE 174
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446369300 135 IASIVDKS--SVNcrKIFQRARKSILEK-----PKQSKLSTEKMAAYVEKFVSSLQCGDAEGMLEVLKTDAIL 200
Cdd:PRK08241 175 VAELLDTSvaAVN--SALQRARATLAERgpsaaDTLREPDDPEERALLARYVAAFEAYDVDALVALLTEDATW 245
Sig70_bacteroi1 TIGR02985
RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors ...
4-137 8.68e-20

RNA polymerase sigma-70 factor, Bacteroides expansion family 1; This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found primarily in the genus Bacteroides. This family appears to have resulted from a lineage-specific expansion as B. thetaiotaomicron VPI-5482, Bacteroides forsythus ATCC 43037, Bacteroides fragilis YCH46 and Bacteroides fragilis NCTC 9343 contain 25, 12, 24 and 23 members, respectively. There are currentlyonly two known members of this family outside of the Bacteroides, in Rhodopseudomonas and Bradyrhizobium.


Pssm-ID: 274376 [Multi-domain]  Cd Length: 161  Bit Score: 83.77  E-value: 8.68e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300    4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMWL 82
Cdd:TIGR02985   4 EQLYRRYYPKLCAFARRYVKDEEDAEDIVQDVFLKLwENRETLEISESIKAYLFTIVKNRCLNYLRHKQVEEKYQEELAE 83
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 446369300   83 PEPLVEESDEPSESFVMKEsLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIAS 137
Cdd:TIGR02985  84 IEERELSEADPEEELEAKE-LEEIIEEAIEKLPEQCREIFILSRFEGLSNKEIAE 137
PRK12542 PRK12542
RNA polymerase sigma factor; Provisional
4-157 3.52e-18

RNA polymerase sigma factor; Provisional


Pssm-ID: 183581 [Multi-domain]  Cd Length: 185  Bit Score: 80.48  E-value: 3.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQS--IENMKAYLCKMATNRSIDKLRSaaHKRNVYVGM 80
Cdd:PRK12542  12 EELYELYEQKVYYVAYSILNNIQQAEDAVQETFITLyKNLEKLHSlnTQELKRYILRVAKNKAIDSYRK--NKRHETFLE 89
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446369300  81 WLPEPLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSI 157
Cdd:PRK12542  90 EYERESIEAVDENIEEWEKRKMSEVQIDTLLKELNESNRQVFKYKVFYNLTYQEISSVMGITEANVRKQFERARKRV 166
PRK11924 PRK11924
RNA polymerase sigma factor; Provisional
4-159 1.61e-17

RNA polymerase sigma factor; Provisional


Pssm-ID: 183384 [Multi-domain]  Cd Length: 179  Bit Score: 78.09  E-value: 1.61e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFIS-LNNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMWL 82
Cdd:PRK11924  16 SELFRPHAPDLLRYARRQLGDRALAEDAVQEAFLRaWRKADLFNGKGSARTWLLTIARNVCYDLLRRRRREKAVLSDDAL 95
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446369300  83 PEPLVEESDEPSESFVMKESLStAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILE 159
Cdd:PRK11924  96 EPEFAETAETPEAALLAKDDLA-RIDRCLDALPVKQREVFLLRYVEGLSYREIAEILGVPVGTVKSRLRRARQLLRE 171
PRK09639 PRK09639
RNA polymerase sigma factor SigX; Provisional
4-155 1.62e-16

RNA polymerase sigma factor SigX; Provisional


Pssm-ID: 236602 [Multi-domain]  Cd Length: 166  Bit Score: 75.37  E-value: 1.62e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNiENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNvyvgMWLP 83
Cdd:PRK09639   6 EDLFEQYYPDVVQQIFYIVKDRTQAEDLAQEVFLRLYR-SDFKGIENEKGWLIKSARNVAYNYLRSEKRRRA----RILG 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446369300  84 EPLVEESDE---PSESFVMKESLSTAYlLLLQQLSEVERIVFILREVfSYEYEEIASI--VDKSSVncRKIFQRARK 155
Cdd:PRK09639  81 EFQWQEVDNepsPEEIWIRKEEITKVQ-EVLAKMTERDRTVLLLRFS-GYSYKEIAEAlgIKESSV--GTTLARAKK 153
PRK09652 PRK09652
RNA polymerase sigma factor RpoE; Provisional
4-160 1.56e-15

RNA polymerase sigma factor RpoE; Provisional


Pssm-ID: 236608 [Multi-domain]  Cd Length: 182  Bit Score: 72.92  E-value: 1.56e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRsaAHKRNVYVGM-- 80
Cdd:PRK09652  13 ALLVRRYQPRVKRLLSRLTRDPADAEDLVQETFIKAyRALHSFRGGAAFYTWLYRIARNTAINYLR--KQGRRPPASDvd 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  81 ------WLPEPLVEESDEPSESFV---MKESLSTAylllLQQLSEVERIVFILREV--FSyeYEEIASIVD------KSs 143
Cdd:PRK09652  91 aeeaedFDLADALRDISTPENELLsaeLEQRVRAA----IESLPEELRTAITLREIegLS--YEEIAEIMGcpigtvRS- 163
                        170
                 ....*....|....*..
gi 446369300 144 vncrKIFqRARKSILEK 160
Cdd:PRK09652 164 ----RIF-RAREALRAK 175
PRK09640 PRK09640
RNA polymerase sigma factor SigX; Reviewed
4-160 1.67e-15

RNA polymerase sigma factor SigX; Reviewed


Pssm-ID: 236603 [Multi-domain]  Cd Length: 188  Bit Score: 73.05  E-value: 1.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFIS-LNNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMWL 82
Cdd:PRK09640  29 EELMRRYQRTLFNVCARYLGNDRDADDVCQEVMLKvLYGLKNFEGKSKFKTWLYSITYNECITQYRKERRKRRLMDALSL 108
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300  83 pEPLVEESDEPSEsfvmKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:PRK09640 109 -DPLEEASEEKAP----KPEERGGLDRWLVHVNPIDREILVLRFVAELEFQEIADIMHMGLSATKMRYKRALDKLREK 181
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
6-71 6.47e-15

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 68.00  E-value: 6.47e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446369300    6 LYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMK--AYLCKMATNRSIDKLRSAA 71
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLwRAIERFDPERGVSfsTWLYTIIRNAIIDYLRKQR 69
PRK12519 PRK12519
RNA polymerase sigma factor; Provisional
6-137 1.19e-10

RNA polymerase sigma factor; Provisional


Pssm-ID: 237125 [Multi-domain]  Cd Length: 194  Bit Score: 59.69  E-value: 1.19e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   6 LYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQSIE-NMKAYLCKMATNRSIDKLRSAAhKRNVYVGMWLPE 84
Cdd:PRK12519  34 LYDRHAGLVYGLALKILGNSQEAEDLTQEIFLSLWRKSSYDPKRgSLSSYLLTLTRSRAIDRLRSRR-SRQRLLERWQQE 112
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446369300  85 PLVEES-DEPSESFVMKEsLSTAYLLLLQQLSEVERIVFilrEVFSYE---YEEIAS 137
Cdd:PRK12519 113 LLGEASeDTPLEQASLAE-RSQRVQTALAQLPESQRQVL---ELAYYEglsQSEIAK 165
PRK09641 PRK09641
RNA polymerase sigma factor SigW; Provisional
5-140 2.50e-10

RNA polymerase sigma factor SigW; Provisional


Pssm-ID: 182012 [Multi-domain]  Cd Length: 187  Bit Score: 58.55  E-value: 2.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   5 QLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFI-SLNNIENIQSIENMKAYLCKMATNRSIDKLRSaaHKRNVYV----- 78
Cdd:PRK09641  22 ELVDLYKDKIYQLCYRMLGNRHEAEDAAQEAFIrAYVNIDSYDINRKFSTWLYRIATNLTIDRLRK--RKPDYYLdaeva 99
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446369300  79 ---GMWLPEPLVEESDEPSESFVMKESLSTAYLLLLqQLSEVERIVFILREVFSYEYEEIASIVD 140
Cdd:PRK09641 100 gteGLTMYSQLAADDALPEEQVVSLELQETIQEAIL-QLPEKYRTVIVLKYIEDLSLKEISEILD 163
PRK09651 PRK09651
RNA polymerase sigma factor FecI; Provisional
4-153 7.68e-10

RNA polymerase sigma factor FecI; Provisional


Pssm-ID: 182018 [Multi-domain]  Cd Length: 172  Bit Score: 56.74  E-value: 7.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRnVYVGMW-- 81
Cdd:PRK09651  13 ESLYGTHHGWLKSWLTRKLQSAFDADDIAQDTFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEK-AYLEMLal 91
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446369300  82 LPEPLVeESDEPSESfvmkeSLSTAYLL--LLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRA 153
Cdd:PRK09651  92 MPEGGA-PSPEERES-----QLETLQLLdsMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSVSSVKKYVAKA 159
PRK09638 PRK09638
RNA polymerase sigma factor SigY; Reviewed
6-140 3.31e-09

RNA polymerase sigma factor SigY; Reviewed


Pssm-ID: 182010 [Multi-domain]  Cd Length: 176  Bit Score: 55.03  E-value: 3.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   6 LYEAYQPLLFSLAYRILGSVMDAEDIVQDVFisLNNIENIQSIEN---MKAYLCKMATNRSIDKLRSaaHKRNVYvgmWL 82
Cdd:PRK09638  23 LFQQHYSFLYKYLLKLTLDPDLAEDLVQETM--LKAIENLSSFQGrskFSTWLISIASRLYKDHLRK--QKREKL---RL 95
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300  83 PEPLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVD 140
Cdd:PRK09638  96 QRAKEETLRKEKWEAAIKGAEWSEMLDALSKLDPEFRAPVILKHYYGYTYEEIAKMLN 153
PRK09644 PRK09644
RNA polymerase sigma factor SigM; Provisional
1-170 3.32e-09

RNA polymerase sigma factor SigM; Provisional


Pssm-ID: 170033 [Multi-domain]  Cd Length: 165  Bit Score: 54.88  E-value: 3.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   1 METEQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQSIENMKAYLCKMATNRSIDKLRSaaHKRNVYVGM 80
Cdd:PRK09644   1 MEIEEIYKMYINDVYRYLFSLTKSHHAAEDLLQETFYRAYIYLEDYDNQKVKPWLFKVAYHTFIDFVRK--EKKVSFVGT 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  81 WLPEPLVEESdepSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEK 160
Cdd:PRK09644  79 DEIEAIQAES---TEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEAASVLDLKLNTYKSHLFRGRKRLKAL 155
                        170
                 ....*....|
gi 446369300 161 PKQSKLSTEK 170
Cdd:PRK09644 156 LKEEKSQNDK 165
SigM_subfam TIGR02950
RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a ...
7-155 6.61e-09

RNA polymerase sigma factor, SigM family; This family of RNA polymerase sigma factors is a member of the Sigma-70 subfamily (TIGR02937) and is restricted to certain lineages of the order Bacillales. This family encompasses at least two distinct sigma factors as two proteins are found in each of B. anthracis, B. subtilis subsp. subtilis str. 168, and B. lichiniformis (although these are not apparently the same two in each). One of these is designated as SigM in B. subtilis (Swiss_Prot:


Pssm-ID: 274361 [Multi-domain]  Cd Length: 154  Bit Score: 53.61  E-value: 6.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300    7 YEAYQPLLFSLAYRILGSVMDAEDIVQDVFI-SLNNIENIQSiENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMwLPEP 85
Cdd:TIGR02950   1 YREYMHDVFRYLYRLTKDKHLAEDLLQETFLkAYIHLHSFKD-SSIKPWLFRIARNAFIDWYRKDKKIQTIDDDA-IGDL 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   86 LVEESDEPSESFVMKESLSTAYLLLlQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARK 155
Cdd:TIGR02950  79 EQHPVESPEHHLLIKIEQEEITHHL-SRLPENYRTVLILREFKEFSYKEIAELLNLSLAKVKSNLFRARK 147
Sigma70_r4_2 pfam08281
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
106-157 2.99e-08

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif.


Pssm-ID: 400535 [Multi-domain]  Cd Length: 54  Bit Score: 49.38  E-value: 2.99e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 446369300  106 AYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSI 157
Cdd:pfam08281   3 ALLRALEELPPRQREVFLLRYLEGLSYAEIAELLGISEGTVKSRLSRARKKL 54
PRK06811 PRK06811
RNA polymerase factor sigma-70; Validated
4-157 7.59e-08

RNA polymerase factor sigma-70; Validated


Pssm-ID: 180707 [Multi-domain]  Cd Length: 189  Bit Score: 51.48  E-value: 7.59e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDI---VQDVFISL-NNIENIQS-IENMKAYLCKMATNRSIDKLRSAAHKRNVYv 78
Cdd:PRK06811  21 EFIVDTYGNLVKKIVHKVLGTVNYSQLIeecVNDIFLSIwNNIDKFDEeKGSFKKWIAAISKYKAIDYKRKLTKNNEID- 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  79 gmwLPEPLVEESDEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASI--VDKSSVNCRkiFQRARKS 156
Cdd:PRK06811 100 ---SIDEFILISEESIENEIILKENKEEILKLINDLEKLDREIFIRRYLLGEKIEEIAKKlgLTRSAIDNR--LSRGRKK 174

                 .
gi 446369300 157 I 157
Cdd:PRK06811 175 L 175
PRK12532 PRK12532
RNA polymerase sigma factor; Provisional
28-159 1.98e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 171564 [Multi-domain]  Cd Length: 195  Bit Score: 50.31  E-value: 1.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  28 AEDIVQDVFIS-LNNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYV------------------GMWLPEPLVE 88
Cdd:PRK12532  33 AEDLVQETLLSaYSAGDSFQGRALVNSWLFAILKNKIIDALRQIGRQRKVFTllddelldeafeshfsqnGHWTPEGQPQ 112
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446369300  89 ESDEPSESFVMKEsLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILE 159
Cdd:PRK12532 113 HWNTPEKSLNNNE-FQKILQSCLYNLPENTARVFTLKEILGFSSDEIQQMCGISTSNYHTIMHRARESLRQ 182
PRK07037 PRK07037
extracytoplasmic-function sigma-70 factor; Validated
5-71 3.18e-07

extracytoplasmic-function sigma-70 factor; Validated


Pssm-ID: 180803 [Multi-domain]  Cd Length: 163  Bit Score: 49.30  E-value: 3.18e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446369300   5 QLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQSIENMKAYLCKMATNRSIDKLRSAA 71
Cdd:PRK07037   2 DVFVDNRSMLVKIAARIVGCRSRAEDVVQDAFVKLVEAPNQDAVKQPVAYLFRIVRNLAIDHYRRQA 68
PRK12538 PRK12538
RNA polymerase sigma factor; Provisional
15-159 6.47e-07

RNA polymerase sigma factor; Provisional


Pssm-ID: 139048 [Multi-domain]  Cd Length: 233  Bit Score: 49.47  E-value: 6.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  15 FSLAYRILGSVMDAEDIVQDVFISL--NNIENIQSIENMKAYLCKMATNRSIDkLRSAAHKRNVYVgmwLPEPlveESDE 92
Cdd:PRK12538  77 YAIALRIVGNRADAEDVVQDTMLKVwtHRGRWQHGRAKFSTWLYRVVSNRCID-LRRKPRTENVDA---VPEV---ADGK 149
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446369300  93 PSESFVMKESLSTAYL-LLLQQLSEVERIVFILrevfSYEYE----EIASIVDKSSVNCRKIFQRARKSILE 159
Cdd:PRK12538 150 PDAVSVIERNELSDLLeAAMQRLPEQQRIAVIL----SYHENmsngEIAEVMDTTVAAVESLLKRGRQQLRD 217
PRK09415 PRK09415
RNA polymerase factor sigma C; Reviewed
4-155 6.59e-07

RNA polymerase factor sigma C; Reviewed


Pssm-ID: 181835 [Multi-domain]  Cd Length: 179  Bit Score: 48.59  E-value: 6.59e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFI-SLNNIENIQSIENMKAYLCKMATNRSIDKLRSaAHKRNVYVGMWL 82
Cdd:PRK09415  19 DEIMNEYGQEVLQLVYSYVKNKEVAEDLTQEIFVkCYKSLHTYKGKSSLKTWLYRIAINHCKDYLKS-WHNKKVIVTEDI 97
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300  83 PEPLVEESDEPSESFVMK---ESLSTAYLLLLQQLSEVerivfilreVFSYEYEE--IASIVDKSSVNCRKIFQRARK 155
Cdd:PRK09415  98 FTYMESQKESVEEEVIQNaedERLASAVMSLPIKYREV---------IYLFYYEElsIKEIAEVTGVNENTVKTRLKK 166
PRK09637 PRK09637
RNA polymerase sigma factor SigZ; Provisional
1-136 8.41e-07

RNA polymerase sigma factor SigZ; Provisional


Pssm-ID: 236601 [Multi-domain]  Cd Length: 181  Bit Score: 48.06  E-value: 8.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   1 METEQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRSaaHKRNVYvg 79
Cdd:PRK09637   1 MKLESIWSEYKAQLKAFLHSRVSNEADVDDLLQEVLIKThSNLHSLKDGSSIKSWLYQIANNTIIDFYRK--KNRSEE-- 76
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446369300  80 mwLPEPLVEESDEPSESFvmKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIA 136
Cdd:PRK09637  77 --LPDDLLFEDEEREENA--KKELAPCLRPFIDALPEKYAEALRLTELEGLSQKEIA 129
PRK12513 PRK12513
RNA polymerase sigma factor; Provisional
4-139 1.23e-06

RNA polymerase sigma factor; Provisional


Pssm-ID: 183566 [Multi-domain]  Cd Length: 194  Bit Score: 48.15  E-value: 1.23e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLnnienIQSIENMK------AYLCKMATNRSIDKLRSAAHKRnvy 77
Cdd:PRK12513  29 EALYARHRTGLYRFLLRLARDRALAEDIFQETWLRV-----IRARAQYQprarfrTWLYQIARNLLIDHWRRHGARQ--- 100
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446369300  78 vgmwLPEPLVEES------DEPS-----ESFVMKESLSTAylllLQQLSEVERIVFILREVFSYEYEEIASIV 139
Cdd:PRK12513 101 ----APSLDADEQlhaladDGAApeqqlSLFRDRRRLQAA----LETLPDEQREVFLLREHGDLELEEIAELT 165
PRK12527 PRK12527
RNA polymerase sigma factor; Reviewed
10-147 2.12e-06

RNA polymerase sigma factor; Reviewed


Pssm-ID: 171560 [Multi-domain]  Cd Length: 159  Bit Score: 46.69  E-value: 2.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  10 YQPLLFSLAYRiLGSVMDAEDIVQDVFISLNNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRnvyvgmwlPEPL-VE 88
Cdd:PRK12527   5 YRELVRFLSAR-LGNRQAAEDVAHDAYLRVLERSSSAQIEHPRAFLYRTALNLVVDRHRRHRVRQ--------AEPLeVL 75
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446369300  89 ESDE----PSESFVMKESLSTAYL-LLLQQLSEVERIVFILREVFSYEYEEIA-------SIVDKSSVN----CR 147
Cdd:PRK12527  76 DEEErlhsPSPQTRLDLGQRLALLqRALAELPPACRDSFLLRKLEGLSHQQIAehlgisrSLVEKHIVNamkhCR 150
PRK12514 PRK12514
RNA polymerase sigma factor; Provisional
6-69 1.41e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 105710 [Multi-domain]  Cd Length: 179  Bit Score: 44.81  E-value: 1.41e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446369300   6 LYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQSIENMK--AYLCKMATNRSIDKLRS 69
Cdd:PRK12514  24 LYDATSAKLFGICLRVLKDRSEAEEALQDVYVKIWTKADRFAVSGLSpmTWLITIARNHAIDRLRA 89
PRK12522 PRK12522
RNA polymerase sigma factor; Provisional
1-160 1.81e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 183571 [Multi-domain]  Cd Length: 173  Bit Score: 44.09  E-value: 1.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   1 METEQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVyVG 79
Cdd:PRK12522   3 EKVEELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVfSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKDR-IL 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  80 MWLPEPLVEESDEPSESFVMKESLSTAYLLLLQQ----LSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARK 155
Cdd:PRK12522  82 DLFHKEDGGEIEFADDVNISEEFIQKVEAEMIREviqlLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKK 161

                 ....*
gi 446369300 156 SILEK 160
Cdd:PRK12522 162 QMREH 166
PRK12523 PRK12523
RNA polymerase sigma factor; Reviewed
6-136 2.88e-05

RNA polymerase sigma factor; Reviewed


Pssm-ID: 183572 [Multi-domain]  Cd Length: 172  Bit Score: 43.69  E-value: 2.88e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   6 LYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRnVYVG--MWLP 83
Cdd:PRK12523  15 LYRDHRGWLLAWLRRNVACRQRAEDLSQDTFVRLLGRPELPTPREPRAFLAAVAKGLMFDHFRRAALEQ-AYLAelALVP 93
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446369300  84 EplvEESDEPSESFVMKESLStAYLLLLQQLSEVERIVFILREVFSYEYEEIA 136
Cdd:PRK12523  94 E---AEQPSPEEQHLILEDLK-AIDRLLGKLSSKARAAFLYNRLDGMGHAEIA 142
PRK09645 PRK09645
ECF RNA polymerase sigma factor SigL;
5-128 3.10e-05

ECF RNA polymerase sigma factor SigL;


Pssm-ID: 236605 [Multi-domain]  Cd Length: 173  Bit Score: 43.53  E-value: 3.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   5 QLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFI-SLNNIENI-QSIENMKAYLCKMATNRSIDKLRSaAHKRNVYVGmwl 82
Cdd:PRK09645  13 ALYDEHAAPLWRYALRLTGDRARAEDVVQETLLrAWQHPEVLaDTGRSARAWLFTVARNLVIDERRS-ARARPVEGG--- 88
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 446369300  83 PEPL-VEESDEPSESFVMKESL--STAylllLQQLSEVERIVfiLREVF 128
Cdd:PRK09645  89 DDVLgVPEQSAPDEVDRALDRLlvADA----LAQLSPEHRAV--LVRSY 131
PRK12524 PRK12524
RNA polymerase sigma factor; Provisional
6-140 3.61e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 183573 [Multi-domain]  Cd Length: 196  Bit Score: 43.73  E-value: 3.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   6 LYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNI--ENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMwlP 83
Cdd:PRK12524  31 LTLRLAPRALAVATRVLGDRAEAEDVTQEAMLRLWRIapDWRQGEARVSTWLYRVVCNLCTDRLRRRRRASVDLDDA--P 108
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300  84 EPlveESDEPSESFVMKESLSTAYL-LLLQQLSEVERIVFILREVFSYEYEEIASIVD 140
Cdd:PRK12524 109 EP---ADAAPGAEEALIEGDRMRALdAALAALPERQRQAVVLRHIEGLSNPEIAEVME 163
PRK12541 PRK12541
RNA polymerase sigma factor; Provisional
4-155 4.38e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 183580 [Multi-domain]  Cd Length: 161  Bit Score: 43.00  E-value: 4.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFI-SLNNIENIQSiENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMW- 81
Cdd:PRK12541   8 EEIYSEHMQDLFRYLLSLTGDSHFAEDLMQETFYrMLVHIDYYKG-EEIRPWLFTIAYNAFIDWYRKEKKYKTTTIEEFh 86
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446369300  82 -LPEPLVEEsdepsESFVMKESLStaYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARK 155
Cdd:PRK12541  87 lPNVPSTEH-----EYFIKHEIAS--WLDSLSSLPLERRNVLLLRDYYGFSYKEIAEMTGLSLAKVKIELHRGRK 154
PRK12530 PRK12530
RNA polymerase sigma factor; Provisional
28-154 8.56e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 237128 [Multi-domain]  Cd Length: 189  Bit Score: 42.45  E-value: 8.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  28 AEDIVQDVFIS-LNNIENIQSIENMKAYLCKMATNRSIDKLRSaaHKRNVYV----------------GMWLPEPLVEES 90
Cdd:PRK12530  34 AEDVVQEALVSaYKNADSFKGQSALKTWIFAILKNKIIDLIRY--RKRFVNEselieedspnsffdekGHWKPEYYEPSE 111
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446369300  91 DEPSESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRAR 154
Cdd:PRK12530 112 WQEVENTVYKEEFWLIFEACLNHLPAQQARVFMMREYLELSSEQICQECDISTSNLHVLLYRAR 175
PRK12518 PRK12518
RNA polymerase sigma factor; Provisional
5-138 1.03e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 237124 [Multi-domain]  Cd Length: 175  Bit Score: 42.01  E-value: 1.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   5 QLYEAYQPLLFSLAYRILGSVMdAEDIVQDVFISL-NNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMWLP 83
Cdd:PRK12518  15 QLYRRYQQKVRSTLYQLCGREL-LDDLVQEVFLRVwKGLPKLRNPAYFSTWLYRITWNVATDARRQFAQRPSRIQDDSLN 93
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446369300  84 EPLVEESDEPSESFVMKESLSTAYLlllQQLSEVERIVFILREVFSYEYEEIASI 138
Cdd:PRK12518  94 DQPSRPSDTPDLMQLHYQDLVQQGL---QTLSLEHRAVLVLHDLEDLPQKEIAEI 145
PRK12534 PRK12534
RNA polymerase sigma factor; Provisional
4-76 1.34e-04

RNA polymerase sigma factor; Provisional


Pssm-ID: 183576 [Multi-domain]  Cd Length: 187  Bit Score: 41.96  E-value: 1.34e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLnnIENIQSIENMKA----YLCKMATNRSIDKLRS-AAHKRNV 76
Cdd:PRK12534  28 EALYRQTSPKLFGVCLRMIPQRAEAEEVLQDVFTLI--WHKAGQFDPSRArgltWLAMIARNKAIDHLRAnAPQRRNV 103
PRK09647 PRK09647
RNA polymerase sigma factor SigE; Reviewed
4-138 2.38e-04

RNA polymerase sigma factor SigE; Reviewed


Pssm-ID: 236606 [Multi-domain]  Cd Length: 203  Bit Score: 41.31  E-value: 2.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   4 EQLYEAYQPLLFSLAYRILGSVMDAEDIVQDVFISLnnienIQSIEN-----MKAYLCKMATNRSIDKLRSAAHKRnvyv 78
Cdd:PRK09647  31 EELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRV-----FRSLQNyqpgtFEGWLHRITTNLFLDMVRRRARIR---- 101
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446369300  79 gMwlpEPLVEE-----SDEPSESFVMKES-LSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASI 138
Cdd:PRK09647 102 -M---EALPEDydrvpGDEPNPEQIYHDArLDPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIAAT 163
PRK09648 PRK09648
RNA polymerase sigma factor ShbA;
23-142 5.75e-04

RNA polymerase sigma factor ShbA;


Pssm-ID: 236607 [Multi-domain]  Cd Length: 189  Bit Score: 39.95  E-value: 5.75e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  23 GSVMDAEDIVQDVFISLnnienIQSIENMK-------AYLCKMATNRSIDKLRSAAhkRNVYVGMW-LPEplvEESDEPS 94
Cdd:PRK09648  50 RPGLSADDVAQEVCLAV-----ITALPRYRdqgrpflAFVYGIAAHKVADAHRAAG--RDKAVPTEeVPE---RPSDDAG 119
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 446369300  95 -ESFVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKS 142
Cdd:PRK09648 120 pEERALRSESSNRMRELLDTLPEKQREILILRVVVGLSAEETAEAVGST 168
PRK05602 PRK05602
RNA polymerase sigma factor; Reviewed
12-138 1.75e-03

RNA polymerase sigma factor; Reviewed


Pssm-ID: 235530 [Multi-domain]  Cd Length: 186  Bit Score: 38.48  E-value: 1.75e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  12 PLLFSLAYRILGSVMDAEDIVQDVFISL-NNIENIQS-IENMKAYLCKMATNRSIDKLRsaahKRNVYVGMWLPEPlVEE 89
Cdd:PRK05602  31 PRLLALATRMLGDPAEAEDVAQETFLRIwKQAPSWRPgEARFDTWLHRVVLNLCYDRLR----RRREVPVEDAPDV-PDP 105
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 446369300  90 SDEPSESFVMKES---LSTAylllLQQLSEVERIVFILrevfsYEYEEIASI 138
Cdd:PRK05602 106 APGPDAGLEARQRarrVEQA----LAALPERQREAIVL-----QYYQGLSNI 148
PRK06930 PRK06930
positive control sigma-like factor; Validated
62-164 2.10e-03

positive control sigma-like factor; Validated


Pssm-ID: 180757 [Multi-domain]  Cd Length: 170  Bit Score: 38.17  E-value: 2.10e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  62 RSIDklRSAAHKRNVYVGMWLPEPLVEESD------EPSESFV-------MKESLSTayllllqqLSEVERIVFILREVF 128
Cdd:PRK06930  60 RGID--RRAAYQREVICDPLLIQRYFRSMEdlewdiEEPESVIsewdkirIEDALSV--------LTEREKEVYLMHRGY 129
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446369300 129 SYEYEEIASIVDKSSVNCRKIFQRARKSILEKPKQS 164
Cdd:PRK06930 130 GLSYSEIADYLNIKKSTVQSMIERAEKKIARQINES 165
PRK12544 PRK12544
RNA polymerase factor sigma-70;
22-154 4.01e-03

RNA polymerase factor sigma-70;


Pssm-ID: 183583 [Multi-domain]  Cd Length: 206  Bit Score: 37.86  E-value: 4.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  22 LGSVMDAEDIVQDVFIS-LNNIENIQSIENMKAYLCKMATNRSIDKLRSaaHKRNVYVGMWLPEPLVEES---------- 90
Cdd:PRK12544  39 LSDLHLAEDAVQEALIGaLKNADSFAGRAAFKTWVFAILKNKIIDLLRQ--KKRHVSASSLLRDEEEEEDfeelfdesgh 116
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446369300  91 ----------DEPSESfVMKESLSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRAR 154
Cdd:PRK12544 117 wqkderpqawGNPEES-LEQEQFWRIFEACLDGLPAKYARVFMMREFIELETNEICHAVDLSVSNLNVLLYRAR 189
PRK09642 PRK09642
RNA polymerase sigma factor;
8-166 4.65e-03

RNA polymerase sigma factor;


Pssm-ID: 170031 [Multi-domain]  Cd Length: 160  Bit Score: 37.00  E-value: 4.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300   8 EAYQPLLFSLAYRILGSVMDAEDIVQDVFISLNNIENIQSIENMKAYLCKMATNRSIDKLRSAAHKRNVYVGMWLPEPLV 87
Cdd:PRK09642   2 QTYRHYIFQVIFSILRHEEDAKDVTQEVFVKIHASLPNYQFRGLKTWMARIATNHAIDYKRKKARENEELSLCKETEENI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446369300  88 EESDEPSESFVMKESlstaYLLLLQQLSEVE---RIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSILEKPKQS 164
Cdd:PRK09642  82 KSSHNIEDLLLTKEQ----KLLIAQKLRELPenyRDVVLAHYLEEKSYQEIALQEKIEVKTVEMKLYRARKWIKKHWKEE 157

                 ..
gi 446369300 165 KL 166
Cdd:PRK09642 158 EF 159
PRK12543 PRK12543
RNA polymerase sigma factor; Provisional
88-140 6.85e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 183582 [Multi-domain]  Cd Length: 179  Bit Score: 36.64  E-value: 6.85e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446369300  88 EESDEPSESFVMKESlSTAYLLLLQQLSEVERIVFILREVFSYEYEEIASIVD 140
Cdd:PRK12543  93 PVSIDFSEDVLSKES-NQELIELIHKLPYKLRQVIILRYLHDYSQEEIAQLLQ 144
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
111-157 9.44e-03

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 33.62  E-value: 9.44e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 446369300 111 LQQLSEVERIVFILREVFSYEYEEIASIVDKSSVNCRKIFQRARKSI 157
Cdd:cd06171    8 LDKLPEREREVILLRFGEGLSYEEIAEILGISRSTVRQRLHRALKKL 54
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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