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Conserved domains on  [gi|446373220|ref|WP_000451075|]
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MULTISPECIES: oligopeptide ABC transporter permease [Bacillus]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 18-301 5.45e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 340.17  E-value: 5.45e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  18 ASSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRI 97
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  98 SLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSewkvpsdYRLYVIMIILSLVGW 177
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG-------PGLLNVILALGLTGW 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 178 PGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGN 257
Cdd:COG1173  154 PGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGT 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446373220 258 MISAANSLIdfQKRPWLWIPPGFAIFITVVSINLLGDALRDALD 301
Cdd:COG1173  234 MLSEGRNYL--LTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 18-301 5.45e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 340.17  E-value: 5.45e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  18 ASSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRI 97
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  98 SLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSewkvpsdYRLYVIMIILSLVGW 177
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG-------PGLLNVILALGLTGW 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 178 PGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGN 257
Cdd:COG1173  154 PGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGT 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446373220 258 MISAANSLIdfQKRPWLWIPPGFAIFITVVSINLLGDALRDALD 301
Cdd:COG1173  234 MLSEGRNYL--LTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 33-301 4.22e-69

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 215.33  E-value: 4.22e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220   33 KMALVGFYALIFMFLFcfiGPFFSPYASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRISLTIGLASMVLSVIL 112
Cdd:TIGR02790   2 VSALLIIAVLFLLAIF---APWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  113 GALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSewkvPSdyrLYVIMIILSLVGWPGLARLVRGQILSLR 192
Cdd:TIGR02790  79 GLLIGGLAGYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILG----PG---LENVIIAIVLVHWAWYARMVRGMVVSLK 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  193 EQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGNMISAANSLIdfQKRP 272
Cdd:TIGR02790 152 QREFVLAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYI--WTQP 229

                         250       260
                  ....*....|....*....|....*....
gi 446373220  273 WLWIPPGFAIFITVVSINLLGDALRDALD 301
Cdd:TIGR02790 230 LLMIYPGLAILISVMAFNLLGDALRDHLG 258
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 20-306 3.00e-64

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 204.58  E-value: 3.00e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  20 SPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPY-ASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRIS 98
Cdd:PRK15082  23 TPWHEFWRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYdAENYFDYDALNAGPSLQHWFGVDSLGRDIFSRILVGARIS 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  99 LTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVPsdyrlyvIMIILSLVGWP 178
Cdd:PRK15082 103 LAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMAN-------VIIAVAIFSIP 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 179 GLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGNM 258
Cdd:PRK15082 176 AFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAM 255

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 446373220 259 ISAANSliDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR 306
Cdd:PRK15082 256 LNEARA--DMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPKIKG 301
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 96-296 3.68e-20

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 86.18  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  96 RISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVPSDYRLYV-IMIILSL 174
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGlPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 175 VGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGvVPPTPS 254
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPG 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446373220 255 WGNMISAANSLidfqkrpwlwipPGFAIFITVVSINLLGDAL 296
Cdd:cd06261  161 TGLLLIFAILF------------PGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 113-306 7.16e-18

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 79.65  E-value: 7.16e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  113 GALLGAIAGFYRG-IVDNIIMRLADILMSMPGLPLLIImgaiLSEWKVPSDYRLYVIM-IILSLVGWPGLARLVRGQILS 190
Cdd:pfam00528   1 GIPLGIIAALRRGrRLDRLLRPLIDLLQALPSFVLAIL----LVVIAILSILGHGILPaIILALLGWAGYARLIRRAALR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  191 LREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYL----GLGVVPPTPSWGNMISaansli 266
Cdd:pfam00528  77 SLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP------ 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 446373220  267 dfqkrpwLWIPPGFAIFITVVSINLLGDALRDALDPKMRR 306
Cdd:pfam00528 151 -------EIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 18-301 5.45e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 340.17  E-value: 5.45e-118
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  18 ASSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRI 97
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAAHWLGTDQLGRDVLSRLLYGARI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  98 SLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSewkvpsdYRLYVIMIILSLVGW 177
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLG-------PGLLNVILALGLTGW 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 178 PGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGN 257
Cdd:COG1173  154 PGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGT 233

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446373220 258 MISAANSLIdfQKRPWLWIPPGFAIFITVVSINLLGDALRDALD 301
Cdd:COG1173  234 MLSEGRNYL--LTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 33-301 4.22e-69

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 215.33  E-value: 4.22e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220   33 KMALVGFYALIFMFLFcfiGPFFSPYASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRISLTIGLASMVLSVIL 112
Cdd:TIGR02790   2 VSALLIIAVLFLLAIF---APWIAPHDPLAQNLPMRLLGPSMEYWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVLTI 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  113 GALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSewkvPSdyrLYVIMIILSLVGWPGLARLVRGQILSLR 192
Cdd:TIGR02790  79 GLLIGGLAGYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILG----PG---LENVIIAIVLVHWAWYARMVRGMVVSLK 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  193 EQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGNMISAANSLIdfQKRP 272
Cdd:TIGR02790 152 QREFVLAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYI--WTQP 229

                         250       260
                  ....*....|....*....|....*....
gi 446373220  273 WLWIPPGFAIFITVVSINLLGDALRDALD 301
Cdd:TIGR02790 230 LLMIYPGLAILISVMAFNLLGDALRDHLG 258
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 20-306 3.00e-64

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 204.58  E-value: 3.00e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  20 SPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPY-ASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRIS 98
Cdd:PRK15082  23 TPWHEFWRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYdAENYFDYDALNAGPSLQHWFGVDSLGRDIFSRILVGARIS 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  99 LTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVPsdyrlyvIMIILSLVGWP 178
Cdd:PRK15082 103 LAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMAN-------VIIAVAIFSIP 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 179 GLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGNM 258
Cdd:PRK15082 176 AFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAM 255

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 446373220 259 ISAANSliDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR 306
Cdd:PRK15082 256 LNEARA--DMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPKIKG 301
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
22-305 1.21e-62

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 200.04  E-value: 1.21e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  22 WRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRISLTI 101
Cdd:PRK09881  20 GAKLVWMLKGSPLTVTGAVIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILA 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 102 GLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSewkvPSdyrLYVIMIILSLVGWPGLA 181
Cdd:PRK09881 100 GLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALG----PS---LFNAMLAIAIVRIPFYV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 182 RLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGNMISA 261
Cdd:PRK09881 173 RLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVAN 252

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 446373220 262 ANSLIDFQKrpWLWIPPGFAIFITVVSINLLGDALRDALDPKMR 305
Cdd:PRK09881 253 GRNYVLDQW--WYCAFPGAAILLTAVGFNLFGDGIRDLLDPKAG 294
nikC PRK10417
nickel transporter permease NikC; Provisional
 36-305 5.86e-61

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 194.89  E-value: 5.86e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  36 LVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHWLGTDQLGRDILTRLMQAGRISLTIGLASMVLSVILGAL 115
Cdd:PRK10417   7 RLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLV 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 116 LGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEwkvpsdyRLYVIMIILSLVGWPGLARLVRGQILSLREQA 195
Cdd:PRK10417  87 IGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGT-------GLTNVIIAIALSHWAWYARMVRSLVISLRQRE 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 196 FMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPPTPSWGNMISAANSLIdfQKRPWLW 275
Cdd:PRK10417 160 FVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYI--WTQPLLM 237

                        250       260       270
                 ....*....|....*....|....*....|
gi 446373220 276 IPPGFAIFITVVSINLLGDALRDALDPKMR 305
Cdd:PRK10417 238 FWPGLALFISVMAFNLLGDALRDHLDPHLV 267
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 2-305 2.44e-59

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 191.97  E-value: 2.44e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220   2 ETVTVITEKKEKKRRnasSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSF--SHWLG 79
Cdd:PRK15406   9 EALENFSEKLEVEGR---SLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPDMesGHYFG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  80 TDQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEwkv 159
Cdd:PRK15406  86 TDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQ--- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 160 psdyRLYVIMIILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGES 239
Cdd:PRK15406 163 ----NILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFES 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446373220 240 ALSYLGLGVVPPTPSWGNMIS-AANSLidfQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMR 305
Cdd:PRK15406 239 FLSFLGLGTQEPLSSWGALLSdGANSM---EVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR 302
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
5-306 2.84e-58

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 189.22  E-value: 2.84e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220   5 TVITEKKEKKRRNASSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPP------SFSHWL 78
Cdd:PRK10913   2 SQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPvwqeggSWAHIL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  79 GTDQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWK 158
Cdd:PRK10913  82 GTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 159 VPSDyrlyvimIILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGE 238
Cdd:PRK10913 162 VNAA-------LALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDM 234

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 239 SALSYLGLGVVPPTPSWGNMISaanSLIDFQKRPWlWIP--PGFAIFITVVSINLLGDALRDALDPKMRR 306
Cdd:PRK10913 235 AALGFLGMGAQPPTPEWGTMLS---DVLQFAQSAW-WVVtfPGLAILLTVLAFNLMGDGLRDALDPKLKQ 300
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
19-304 2.39e-53

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 176.16  E-value: 2.39e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  19 SSPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSF------SHWLGTDQLGRDILTRLM 92
Cdd:COG4171   13 PSPLKQIWQSFRKNPLAMIGLYGFLFLILLALFGPLLAPYSPDQQFIGALLLPPSWddngdvSFFLGTDDLGRDILSRLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  93 QAGRisLTIGLASMV--LSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILsewkvpsDYRLYVIMI 170
Cdd:COG4171   93 YGAR--YTFGSALLVvlAAAIIGGIIGILAGMSRGLKSSILNHLLDTLLSIPSLLLAIIIVALL-------GPGLENAML 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 171 ILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVP 250
Cdd:COG4171  164 AITLALLPQFIHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQL 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446373220 251 PTPSWGNMISAANSLIDFQkrPWLWIPPGFAIFITVVSINLLGDALRDALDPKM 304
Cdd:COG4171  244 PSPEWGAMLGDSLELIYLA--PWTVILPGLAIMFSVLIVNLVGDGLRRALNKGV 295
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 71-304 1.14e-50

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 170.72  E-value: 1.14e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  71 PPSFSHWLGTDQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIM 150
Cdd:COG4239  116 PPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIIL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 151 GAILsewkVPSdyrLYVIMIILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLpilivVSTLG 230
Cdd:COG4239  196 SSIF----QPS---FWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAM-----VATLT 263

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446373220 231 -----VAGSILGESALSYLGLGVVPPTPSWGNMISAANSLIDfqkRPWLWIPPGFAIFITVVSINLLGDALRDALDPKM 304
Cdd:COG4239  264 flpfiLSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQ---APWLGLSAFVVLALMLSLLVFIGEAVRDAFDPRK 339
PRK15111 PRK15111
peptide ABC transporter permease SapC;
20-301 1.34e-37

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 135.21  E-value: 1.34e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  20 SPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPPSFSHW------LGTDQLGRDILTRLMQ 93
Cdd:PRK15111  14 GTLRTAWRKFYSDALAMVGLYGCAGLALLCLFGGWLAPYGIDQQFLGYQLLPPSWSRYgevsffLGTDDLGRDVLSRLLS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  94 AGriSLTIGLASMV--LSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEwkvpsdyRLYVIMII 171
Cdd:PRK15111  94 GA--APTVGGAFVVtlAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGP-------SLSHAMFA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 172 LSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGVVPP 251
Cdd:PRK15111 165 VWLALLPRMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLP 244

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 446373220 252 TPSWGNMISAANSLIdfQKRPWLWIPPGFAIFITVVSINLLGDALRDALD 301
Cdd:PRK15111 245 SPEWGAMLGDSLELI--YVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAII 292
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 71-302 6.83e-34

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 126.64  E-value: 6.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  71 PPSFSHWLGTDQLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIM 150
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 151 GAILSewkvPSDYRLYVIMIILslvGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLG 230
Cdd:PRK15021 196 SSVVQ----PNFWWLLAITVLF---GWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFI 268

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446373220 231 VAGSILGESALSYLGLGVVPPTPSWGN-MISAANSLidfqKRPWLWIPPGFAIFITVVSINLLGDALRDALDP 302
Cdd:PRK15021 269 LCSSITTLTSLDFLGFGLPLGSPSLGElLLQGKNNL----QAPWLGITAFLSVAILLSLLIFIGEAVRDAFDP 337
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 96-296 3.68e-20

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 86.18  E-value: 3.68e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  96 RISLTIGLASMVLSVILGALLGAIAGFYRGIVDNIIMRLADILMSMPGLPLLIIMGAILSEWKVPSDYRLYV-IMIILSL 174
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGlPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 175 VGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYLGLGvVPPTPS 254
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG-EAPGPG 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 446373220 255 WGNMISAANSLidfqkrpwlwipPGFAIFITVVSINLLGDAL 296
Cdd:cd06261  161 TGLLLIFAILF------------PGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 113-306 7.16e-18

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 79.65  E-value: 7.16e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  113 GALLGAIAGFYRG-IVDNIIMRLADILMSMPGLPLLIImgaiLSEWKVPSDYRLYVIM-IILSLVGWPGLARLVRGQILS 190
Cdd:pfam00528   1 GIPLGIIAALRRGrRLDRLLRPLIDLLQALPSFVLAIL----LVVIAILSILGHGILPaIILALLGWAGYARLIRRAALR 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  191 LREQAFMQAADVLGIKDYRKIIYHLIPNVLPILIVVSTLGVAGSILGESALSYL----GLGVVPPTPSWGNMISaansli 266
Cdd:pfam00528  77 SLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYP------ 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 446373220  267 dfqkrpwLWIPPGFAIFITVVSINLLGDALRDALDPKMRR 306
Cdd:pfam00528 151 -------EIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 82-306 1.18e-15

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 75.87  E-value: 1.18e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220  82 QLGRDILTRLMQAGRISLTIGLASMVLSVILGALLGAIAGFYRG-IVDNIIMRLADILMSMP----GLPLLIIMGAIL-- 154
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGsWLDRLITVLALLGISIPsfwlGLLLILLFAVKLgw 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 155 -------SEWKVPSDYRLYVIM--IILSLVGWPGLARLVRGQILSLREQAFMQAADVLGIKDYRKIIYHLIPN-VLPILI 224
Cdd:COG0601  162 lpvsgrvSPWEDFLDALRHLILpaLTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNaLIPVVT 241

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446373220 225 VVS-TLG--VAGSILGESALSYLGLGVVpptpswgnMISAANSLiDFqkrpwlwipP---GFAIFIT--VVSINLLGDAL 296
Cdd:COG0601  242 VLGlQLGglLGGAVVVETVFSWPGLGRL--------LVDAILNR-DY---------PvvqGIVLLIAvlVVLVNLLVDLL 303

                        250
                 ....*....|
gi 446373220 297 RDALDPKMRR 306
Cdd:COG0601  304 YALLDPRIRL 313
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
 20-72 3.08e-12

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 60.50  E-value: 3.08e-12
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 446373220   20 SPWRQAFKKIKKNKMALVGFYALIFMFLFCFIGPFFSPYASGKIQVALINKPP 72
Cdd:pfam12911   1 SPWQDAWRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYDPDQQDLSADLLPP 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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